miRNA-155 mediates down-regulation of the high-affinity receptor for IgE via Toll-like receptor signaling

Publication date: Available online 7 September 2017
Source:Journal of Allergy and Clinical Immunology
Author(s): Nicole Leib, Nadine Herrmann, Susanne Koch, Tim J. Stroisch, Sylvia Schnautz, Helene Wilms, Thomas Bieber

Teaser

miRNA-155 contributes to the inflammatory process in AD by regulating the expression of the high-affinity receptor for IgE (FcεRI) via its transcription factor PU.1. miRNA-155 may represent an interesting new target in AD therapy.


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