Relationship between sjögren's syndrome and periodontal status- a systematic review

Publication date: Available online 11 December 2017
Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Author(s): Luana de Goés Soares, Ricardo Lopes Rocha, Elizabete Bagordakis, Endi Lanza Galvão, Dhelfeson Willya Douglas-de-Oliveira, Saulo Gabriel Moreira Falci
ObjectiveThis study aimed to evaluate if Sjögren's syndrome is related to periodontal status.Study DesignA systematic review was performed based on PRISMA (PROSPERO: CRD42017055202). The search was performed in the PubMed/MEDLINE, LILACS, Web of Science and Science Direct databases. Hand searches and gray literature were also performed. Three researchers independently selected studies, extracted data and assessed methodological quality. Studies that correlated primary and/or secondary SS, with plaque index, gingival index, probing depth and bleeding on probing were included. The risk of bias was estimated based on the Newcastle-Ottawa scale.ResultsSeventeen studies were included, and nine included in the meta-analysis, with a total of 518 and 544 patients, with and without Sjögren's Syndrome, respectively. The mean difference of plaque index (0.29; CI95% 0.17-0.41), gingival index (0.52; CI95% 0.14-0.89) and bleeding on probing (9.92; CI95%4.37-15.47) were larger in SS patients than controls. In primary SS (0.47; CI95% 0.10-0.83) and secondary SS (0.74 CI95% 0.10-1.38), only gingival index mean was larger than in control group. The majority of the included studies were judged as high risk of bias.ConclusionThe present review does not provide strong evidence to ensure that the periodontal status is affected by Sjögren's syndrome.



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