Acute vascular reaction due to lipo-prostaglandin E1

Abstract

Lipo-prostaglandin E1 (Lipo-PGE1) is a PGE1 product in lipid microspheres and acts as a vasodilator. Injection of Lipo-PGE1 is used clinically for chronic skin ulcers caused by collagen diseases, diabetes mellitus and impaired blood circulation. Erythema, vascular pain, and phlebitis of the injected sites are recognized as cutaneous manifestations of the side effects of PGE1. Here we present the first case of acute vascular reaction along veins injected with Lipo-PGE1.

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