Comments on “Compositional and functional variations of oral microbiota associated with the mutational changes in oral cancer” by Yang et al.

We read with great interest the article titled "Compositional and functional variations of oral microbiota associated with the mutational changes in oral cancer" by Yang et al. [1]. We greatly appreciate the author's efforts for exploring the association between mutations in oral cancer and microbiome, thus opening up an interesting avenue in oral microbiome research. Host genetics has already been demonstrated to influence the gut microbiome [2] and the authors of this paper have reported an association between mutations seen in oral cancer with the salivary microbiome.

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