Early removal of sequestrum in patients affected by medication-related osteonecrosis of the jaw

We wish to draw attention to a recent letter by Davies et al,1 in which they point out the importance of removing sequestra in patients with medication-related osteonecrosis of the jaw (MRONJ). They state correctly that there is no gold standard for the surgical or conservative management of MRONJ. Although we agree, we think that early removal of sequestra could be a possible solution. In the case of MRONJ, we learned the value of early removal the hard way, with several failures after conservative approaches.

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