Safe and effective intradermal influenza vaccine desensitization for delayed influenza vaccine allergy

We report a case of an 18-year-old Japanese male with delayed hypersensitivity to influenza virus vaccine, who completed seven years of successful annual vaccine desensitization using intradermal (ID) trivalent split-virion influenza vaccine (IIV3-ID) (Fluzone®, Intradermal, Sanofi Pasteur, Cambridge MA). Informed consent was obtained this repot. At four years of age, the patient was hospitalized for evaluation of possible compartment syndrome in Japan for his first reaction to the intramuscular influenza vaccine when large circumferential swelling developed over a period of 24-48 hours after vaccination, which was successfully treated with intravenous steroids.

http://ift.tt/2EzKTtw