The treatment of vocal process granuloma

We reviewed with great interest the paper entitled "Comparison of the effects of esomeprazole plus mosapride citrate and botulinum toxin A on vocal process granuloma" by Lei et al. [1]. This is an excellent study. The authors compared the effects on vocal process granulomas (VPGs) of proton pump inhibitors (PPI) together with prokinetic agents and injections of botulinum toxin A. It was concluded that combined PPI and prokinetic drugs played a significant role in VPG treatment after surgery. However, the study design is unusual and the inclusion criteria vague.

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