CD40LG duplication-associated autoimmune disease is silenced by non-random X-chromosome inactivation

Publication date: Available online 2 March 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Carole Le Coz, Melissa Trofa, Camille M. Syrett, Anna Martin, Harumi Jyonouchi, Soma Jyonouchi, Montserrat C. Anguera, Neil Romberg

Teaser

An inherited syndrome of autoimmunity associated with CD40LG duplication is silenced by non-random X-chromosome inactivation and is treatable with CD40L directed therapy.


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