Management update of potentially premalignant oral epithelial lesions

Publication date: Available online 23 March 2018
Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Author(s): Michael Awadallah, Matthew Idle, Ketan Patel, Deepak Kademani
The term oral potentially malignant disorders (OPMD) previously defined at the World Health Organisation (W.H.O) workshop in 2005 has now been redefined as potentially premalignant oral epithelial lesions (PPOELs). It is important to differentiate PPOEL's which are a broad term to define a wide variety of clinical lesions from oral epithelial dysplasia which should be reserved specifically for lesions with biopsy proven foci of dysplasia. Unfortunately, the nomenclature is not consistent and many times both terms PPOEL and dysplasia are used interchangeably which adds to confusion in the literature. PPOEL's encompass lesions that include leukoplakia, erythroplakia, erythroleukoplakia, lichen planus, and submucosal fibrosis. The World Health Organization (W.H.O). definition of a histologically proven oral premalignant lesion that is associated with a significantly increased risk of malignant transformation. The primary goal of management of dysplasia includes the prevention, early detection and treatment prior to malignant transformation. The aim of this paper is to inform the clinician about management of PPOELs.



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