Sentinel lymph node biopsy in malignant melanoma of the head and neck

Publication date: Available online 12 April 2018
Source:Journal of Cranio-Maxillofacial Surgery
Author(s): Roman Kia Rahimi-Nedjat, Bilal Al-Nawas, Andrea Tuettenberg, Keyvan Sagheb, Stephan Grabbe, Christian Walter
BackgroundThe aim of this retrospective study was to investigate sentinel lymph node biopsy in patients with head and neck melanoma.Materials and MethodsPatients who underwent SLNB between 2010 and 2016 were comprised. Epidemiological, radiological, and surgical data were collected and compared to histological findings. Patients who underwent primary complete lymph node dissection were excluded.Results74 patients underwent SLNB during this period. The most common tumor localizations were the cheek (20.4%) and ears (20.4%). Overall, 256 sentinel lymph nodes (SLN) were detected and removed, most frequently in Robbins-levels IIA and IIB as well as in the surrounding of the parotid gland. 12.3% of the SLN showed a microscopic or macroscopic metastasis. In preoperative imaging all lymph nodes with macroscopic metastasis were described as suspect but only 4 of 11 lymph nodes with microscopic metastases were described as such.ConclusionsSLNB is an especially good procedure for the diagnosis of microscopically metastases as disease status is an important diagnostic and prognostic factor in early-stage melanoma patients. However, due to the complex lymphatic system in head and neck melanoma, a short follow-up interval is necessary in order to prevent delayed diagnosis of a nodal recurrence due to a false-negative SLN.



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