miRNAs are required for Langerhans cell, skin and lung resident macrophage ontogeny

Publication date: Available online 8 May 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Yi Yao, Carly Martin, Congcong Yin, Chunyuan Guo, Zheng Dong, Li Zhou, Qing-Sheng Mi

Teaser

Capsule summary: Our study demonstrates that miRNAs serve as critical epigenetic regulators in the ontogeny of LCs and TRMs in the skin and lungs, suggesting that miRNAs may be promising targets for LC and TRM-related allergic diseases.


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