Nrf2 pathway modulates Substance P-induced human mast cell activation and degranulation in the hair follicle

Publication date: Available online 31 May 2018
Source:Journal of Allergy and Clinical Immunology
Author(s): Laura Jadkauskaite, Rajia Bahri, Nilofer Farjo, Bessam Farjo, Gail Jenkins, Ranjit Bhogal, Iain Haslam, Silvia Bulfone-Paus, Ralf Paus

Teaser

Activation of Nrf2 in primary human mast cells exposed to oxidative stress induced by substance P suppresses pro-inflammatory gene transcription, activation and degranulation.


https://ift.tt/2JoZ1bg