Subcutaneous allergen immunotherapy may be a suitable treatment for exacerbator allergic asthma

Asthma is a heterogeneous disease which is mainly linked with allergy. Allergen immunotherapy (AIT) is the only specific treatment for allergic diseases with evidence of a disease-modifying effect. Nevertheless, the safety of subcutaneous AIT (SCIT) in asthma has been of some concern since the 1980s, especially in uncontrolled asthma. In this context, our objectives were to assess the safety and efficacy of a Dermatophagoides pteronyssinus (D. pteronyssinus) cluster SCIT protocol in children with moderate to severe allergic asthma.

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