Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Σάββατο 5 Μαΐου 2018

The characteristics and clinical significance of REM<10% in children with sleep-disordered breathing

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Publication date: July 2018
Source:International Journal of Pediatric Otorhinolaryngology, Volume 110
Author(s): Liqiang Yang, Zhenyun Huang, Jianwen Zhong, Shuyao Qiu, Dabo Liu
ObjectiveFractional time in REM sleep <20% ('little REM sleep') is indicative of more severe sleep-disordered breathing (SDB) in adults. We examined if other REM% is predictive of more severe SDB in children.MethodsIn this retrospective study of 616 pediatric SDB patients, age, sex ratio, BMI, sleep efficiency, awakening frequency, sleep latency, apnea-hypopnea index (AHI), obstructive apnea index (OAI), and lowest oxygen pulse saturation (LSpO2) were compared among groups stratified according to REM%: REM≥20%, REM<20%, 15% ≤ REM<20%, 10% ≤ REM<15%, and REM<10%. Correlations with AHI, OAI, LSpO2, sleep efficiency, and awakening frequency were examined in REM<20% and REM<10% groups. Associations of these parameters with REM<10% were examined by single- and multifactor regression.ResultsPediatric SDB patients with little REM sleep demonstrated poorer sleep quality than patients with REM≥20%, while patients with REM<10% also exhibited more severe SDB. Specifically, the REM<20% group exhibited higher number of awakenings and lower sleep efficiency than the REM≥20% group (both P ≤ 0.001), as did each REM%<20% subgroup (lower sleep efficiency: all P < 0.05; higher awakening frequency: all P < 0.001). Moreover, compared to the REM≥20% group, the REM<10% also exhibited higher AHI (P = 0.025) and lower LSpO2 (P = 0.019). In the REM<10% group, individual REM% was negatively correlated with AHI (r = −0.216, P = 0.031) and positively with LSpO2 (r = 0.2, P = 0.046). Multifactor logistic regression correcting for age and BMI identified AHI as an independent predictor of REM<10% (P = 0.012, OR = 1.016, 95% CI [1.004,1.029]).ConclusionREM% <10% is associated with poor sleep quality and SDB severity in children, suggesting that this threshold should define "little REM sleep" in pediatric patients.



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