MRI assessment and histopathological evaluation of subchondral bone remodeling in temporomandibular joint osteoarthritis: A retrospective study

Publication date: Available online 12 June 2018
Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Author(s): Lingzhi Li, Huimin Shi, Han Xie, Lizhen Wang
ObjectiveThe aim was to characterize subchondral bone remodeling using magnetic resonance imaging (MRI) and histopathological assessment of temporomandibular joint osteoarthritis (TMJOA), and to analyze their correlations.Study DesignThe retrospective study was based on 153 joints of 100 patients. These patients had undergone MRI and had been diagnosed with temporomandibular joint internal derangement (TMJID) Wilkes stage IV-V followed by the failure of conservative or arthroscopic/anchorage treatment. We evaluated and compared 136 joints based on MRI and histopathological observation. According to the modified Osteoarthritis Research Society International (OARSI) system and Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) system, the scores of histopathology and MRI were compared using kappa categorical agreement analysis.ResultsMRI showed subchondral bone changes in 153 joints, 136 of which underwent surgical treatment and histopathological assessment. Statistical tests revealed substantial agreement between MRI and histopathology (kappa value: 0.779).ConclusionMRI is an effective technique to evaluate the pathological changes of TMJOA. Our histopathological grading criteria contributed to the clarification of the occurrence and developmental process of TMJOA. Therefore, the evidence of MRI should be seen as a reference standard for the choice of non-surgical or surgical therapy in the management of TMJOA.



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