Proximal-type epithelioid sarcoma of the oral cavity: a case report and literature review

Publication date: Available online 21 June 2018
Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
Author(s): Yutong Liu, Bincan Sun, Yaocheng Yang, Liang Zhong, Xifan He, Mengxue Wang, Kai Wang, Lin Chen
Proximal-type epithelioid sarcoma (PES) is an exceedingly rare malignant tumor of soft tissue; PES within the oral cavity is even rarer. Pathological examination is the primary diagnostic modality and surgical treatment is recommended as the preferred method for the treatment of PES. Currently, there is a paucity of literature that systematically reports on PES in the oral cavity. Here, we describe a 42-year-old man with PES in the oral cavity, which showed positivity for vimentin, cytokeratin, CD31, S-100, but did not express BCL-2, HMB-45, or desmin. We performed a wide excision and neck dissection, then used the free anterolateral thigh flap to reconstruct the defect in the soft tissue. Furthermore, we review the current literature with regard to diagnosis and treatment of PES.



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