A 2018 Reference Guide to the Banff Classification of Renal Allograft Pathology

The Banff Classification of Allograft Pathology is an international consensus classification for the reporting of biopsies from solid organ transplants. Since its initial conception in 1991 for renal transplants, it has undergone review every 2 years, with attendant updated publications. The rapid expansion of knowledge in the field has led to numerous revisions of the classification. The resultant dispersal of relevant content makes it difficult for novices and experienced pathologists to faithfully apply the classification in routine diagnostic work and in clinical trials. This review shall provide a complete and simple illustrated reference guide of the Banff Classification of Kidney Allograft Pathology based on all publications including the 2017 update. It is intended as a concise desktop reference for pathologists and clinicians, providing definitions, Banff Lesion Scores and Banff Diagnostic Categories. An online website reference guide hosted by the Banff Foundation for Allograft Pathology (www.banfffoundation.org) is being developed, which will be updated with future refinement of the Banff Classification from 2019 onwards. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. Received 19 February 2018. Revision received 7 May 2018. Accepted 23 May 2018. Corresponding author: Jan U. Becker, MD, Institute of Pathology, University Hospital of Cologne, Kerpener Str. 62, 50937, Germany, Phone: +4922147898803, Fax: +492214786360, E-mail: janbecker@gmx.com Authors' contribution All authors contributed the discussion of the content, the collation of images and illustrations and to writing of the manuscript. Disclosure: The authors declare no conflicts of interest. Funding Dr. Roufosse's and Dr. Simmond's contribution to this research is supported by the National Institute for Health Research (NIHR) Biomedical Research Centre based at Imperial College Healthcare NHS Trust and Imperial College London. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. Alexandre Loupy is supported by a research grant ATIP AVENIR from the National French Institute of Research. Jan U. Becker is supported by the European Rare Kidney Disease Network (ERKNet); the content of this manuscript is the sole responsibility of the authors. Copyright © 2018 Wolters Kluwer Health, Inc. All rights reserved.

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