In vivo imaging reveals increased eosinophil uptake in the lungs of obese asthmatics

Publication date: Available online 30 July 2018

Source: Journal of Allergy and Clinical Immunology

Author(s): Neda Farahi, Chrystalla Loutsios, Nicola Tregay, Adam K.A. Wright, Rachid Berair, Laurence S.C. Lok, Daniel Gillett, Ian Cullum, Rosalind P. Simmonds, Charlotte Summers, Anna Wong, Chandra K. Solanki, John Buscombe, Pee Hwee Pang, Arthikkaa Thavakumar, A.Michael Peters, Christopher E. Brightling, Alison M. Condliffe, Edwin R. Chilvers

Capsule Summary

Using radiolabeled eosinophils coupled with SPECT/CT the authors quantify eosinophilic inflammation in the lungs of patients with asthma and focal pulmonary eosinophilic inflammation, revealing important differences in eosinophil kinetics between obese and non-obese asthmatics.

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