The effect of different dosage regimens of tranexamic acid on blood loss in bimaxillary osteotomy: a randomized, double-blind, placebo-controlled study

I thank the author of the Letter to the Editor for his interest in our article "The effect of different dosage regimens of tranexamic acid on blood loss in bimaxillary osteotomy: a randomized, double-blind, placebo-controlled study" published in this journal1. I agree that tranexamic acid is not necessary in routine orthognathic surgeries. This drug is also not used routinely at our institution. Since our institution is a training centre, the amount of blood loss reported varies widely2. It is used only in selected cases where high blood loss is predicted, or in patients for whom the allowable blood loss is low, such as those with a low body weight or low haemoglobin level that cannot be corrected.

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