Avocado: An Emerging Culprit in Food Protein-Induced Enterocolitis Syndrome?

Food protein-induced enterocolitis syndrome (FPIES) is a poorly understood, immunologically mediated, gastrointestinal food-associated hypersensitivity often presenting in infants and toddlers.1 Incidence data are limited; estimates vary from 1.5 to 30 per 10,000.2,3 Despite being more prevalent than previously thought, diagnostic delay is common4 and clinician awareness of FPIES appears to be low.5 Reactions are typified by profuse vomiting, often accompanied by diarrhea, lethargy, and pallor; and may be progress to severe dehydration, acidosis, and shock.

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