Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Σάββατο 17 Νοεμβρίου 2018

Gamma‐delta T cell large granular lymphocyte leukemia with multiple cutaneous nodules that showed spontaneous regression

Abstract

T cell large granular lymphocyte leukemia (T‐LGLL) is a rare chronic lymphoproliferative disorder of mature post‐thymic large granular lymphocytes (LGL); either cytotoxic T‐lymphocytes or natural killer cells.1 Major phenotype of LGL cells is TCRαβ+CD3+CD4‐CD5+CD8+CD27‐CD28‐CD45‐CD57+.2 Less than 10% of cases express TCRγδ instead of TCRαβ.2 Most cases of T‐LGLL have an indolent course1 and its cutaneous manifestations have been poorly documented.

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