Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Παρασκευή 7 Δεκεμβρίου 2018

Rebound effect associated with JAK inhibitor use in the treatment of alopecia areata

Abstract

Alopecia areata (AA) is a common autoimmune disease driven by Th1 cytokines characterized by non‐scarring hair loss.1,2 Mouse models have demonstrated that IFN‐γ‐producing NKG2D+ CD8+ cytotoxic T lymphocytes (CTLs) are essential for disease pathogenesis, along with JAK‐STAT dependent cytokines IFN‐γ and IL‐15, which induce autoreactive T cell activation.1,3

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