Publication date: Available online 26 January 2019
Source: Journal of Oral and Maxillofacial Surgery
Author(s): Ideh Talimkhani, Mohammad Reza Jamalpour, Hamed Babaei, Javad Faradmal
Abstract
Introduction
Surgical removal of impacted third molar teeth is one of the most common surgical procedures performed in oral and maxillofacial surgery. Postoperative pain is a common and predictable occurrence following maxillofacial surgery.
Materials and methods
This is a randomized double-blind clinical trial that was conducted with a crossover design in which each patient served as his or her own control. Forty-six patients with similar bilateral impacted lower third molars were selected. In each patient, the intervention and control sides of the mandible were randomly determined at the end of the surgery. If the removed tooth was in the intervention side, the patient would receive bupivacaine and placebo of mefenamic acid. If the impacted tooth was in the control side, the patient would receive mefenamic acid capsule and a placebo of bupivacaine. Pain severity was assessed using a Visual Analogue Scale (VAS). Data were analyzed using Paired sample t-test and P <0.05 was considered statistically significant.
Results
Of 46 participants originally recruited, 43 were included in the current study. The mean of post-operative pain score in the patients who received bupivacaine was increased to a maximum 4 hours, with significant improvements after this time. The mean intensity of pain following administration of bupivacaine was lower than mefenamic acid capsules in the different time points. Statistical analysis showed that there was a significant difference in pain intensity between two studied groups.
Conclusion
The results of the current study showed that local administration of bupivacaine improves the postoperative pain following surgical removal of impacted third molar teeth.
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