Purpose: The study proposed to determine the superiority between locking plate and nonlocking miniplate for mandibular fractures (MFs) treatment. Methods: A comprehensive electronic search examining Medline-Ovid, Embase, and PubMed databases language without date was performed in February 2018. Inclusion criteria were studies in humans, including randomized controlled trials, controlled clinical trials, with the aim of comparing the 2 techniques. The quality of studies was assessed, and the relative risk (RR) with its corresponding 95% confidence interval (CI) was assessed to measure the effect size. Results: Thirteen publications were enrolled into the analysis. The results showed that there were significant differences in overall complications (RR, 0.62; 95% CI, 0.351–1.094; P = 0.06), postoperative infection (RR, 0.503, 95% CI, 0.223–1.136) when comparing locking miniplates with nonlocking miniplates in treating mandible fractures. The incidence of malocclusion showed a statistically significant difference in the outcome favoring locking miniplates (fixed: RR, 0.503; 95% CI, 0.125–2.030; P = 0.06). In addition, the use of locking miniplates had a lower postoperative maxillomandibular fixation rate than the use of nonlocking miniplates (RR, 0.414; 95% CI, 0.196–0.872; P = 0.002). Conclusion: The result of meta-analysis revealed that use of locking plate is superior to the nonlocking plate in the reducing of postoperative complication rates in the management of MFs. Address correspondence and reprint requests to Adili Moming, DDS, MD, Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital, Xinjiang Medical University, No 137, South Li Yu-shan Road, New City District 830054 Urumqi, Xinjiang Uyghur Autonomous Region, China; E-mail: adili928@hotmail.com Received 16 April, 2018 Accepted 22 September, 2018 Financial support by the National Natural Science Funding of China. The authors report no conflicts of interest. Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (http://bit.ly/2iuFjMi). © 2019 by Mutaz B. Habal, MD.
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