Enhancing Adhesion and Alignment of Human Gingival Fibroblasts on Dental Implants

Publication date: Available online 21 February 2019

Source: Journal of Cranio-Maxillofacial Surgery

Author(s): Oral Cenk Aktas, Wolfgang Metzger, Ayman Haidar, Yahya Açil, Aydin Gülses, Jörg Wiltfang, Catharina Marques Sacramento, Frank Philipp Nothdurft

Abstract

Background

Promoting the directional attachment of gingiva to the dental implant leads to the formation of tight connective tissue which acts as a seal against the penetration of oral bacteria. Such a directional growth is mostly governed by the surface texture.

Material and methods

In this study, three different methods, mechanical structuring, chemical etching and laser treatment, have been explored for their applicability in promoting cellular attachment and alignment of human primary gingival fibroblasts (HGFIBs).

Results

The effectiveness of mechanical structuring was shown as a simple and a cost-effective method to create patterns to align HGIFIBs.

Conclusion

Combining mechanical structuring with chemical etching enhnaced both cellular attachment and the cellular alignment.

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