SummaryObjectiveHydrocortisone stress dosing during illness can prevent adrenal crises (AC) in patients with adrenal insufficiency (AI). When patients cannot communicate, medical identification jewellery may facilitate parenteral hydrocortisone provision but patient adoption rates are not known.DesignA cross‐sectional analysis of Australian medical identification jewellery subscription data.PatientsPatients with AI aged 20 years and over with an active subscription to a large medical jewellery...
Tue Apr 09, 2019 12:06
Abstract A phase III study has demonstrated that 6-month pasireotide treatment induced disease control with good safety in 15–26% of patients with Cushing's disease (CD). The aim of the current study was to evaluate the 6-month efficacy and safety of pasireotide treatment according to the real-world evidence. Thirty-two CD patients started pasireotide at the dose of 600 µg twice a day (bid) and with the chance of up-titration to 900 µg bid, or down-titration to 450 or 300 µg bid,...
Tue Apr 09, 2019 03:00
Abstract Several antiresorptive drugs, like bisphosphonates and denosumab, are currently available for the treatment of osteoporosis due to their evidenced efficacy in reducing fracture risk at mid-term. Osteoanabolic therapies, like teriparatide, whose treatment duration is limited to 2 years, have also shown efficacy in the reduction of fracture risk. However, depending on the severity of osteoporosis and the presence of other associated risk factors for fracture, some patients...
Mon Apr 08, 2019 03:00
Abstract Ketogenic diet (KD) compromised the microstructure of cancellous bone and the mechanical property in the appendicular bone of mice, while the effects of KD on the axial bone have not been reported. This study aimed to compare the changes in the microstructure and mechanical properties of the forth lumbar (L4) vertebra in KD and ovariectomized (OVX) mice. Forty eight-week-old female C57BL/6J mice were assigned into four groups: SD (standard diet) + Sham, SD + OVX, KD + Sham,...
Tue Apr 09, 2019 03:00
Abstract Warfarin, a vitamin K antagonist, is the most common anticoagulant used to prevent thromboembolisms associated with atrial fibrillation or following valvular surgery. Although several studies have revealed that long-term warfarin use accelerates aortic valve calcification and the development of aortic stenosis (AS), the detailed mechanism for this phenomenon remains unclear. Therefore, our aim was twofold: to establish the conditions for warfarin-induced calcification...
Mon Apr 08, 2019 03:00
Abstract Background With the use of non-objective measurement, adherence to growth hormone (GH) therapy has been reported suboptimal in a large proportion of patients, and poor adherence has been shown to affect short-term growth response in patients receiving GH treatment. Objective The Easypod™ electronic device allows objective measurement of adherence....
Tue Apr 09, 2019 03:00
Abstract Purpose This is a longitudinal study of retrospective data aimed at verifying whether repeated measurements of serum non-stimulated thyroglobulin (Tg) allow the prediction of persistent disease in patients with differentiated thyroid cancer (DTC) and indeterminate response. Methods We examined 145 DTC patients with indeterminate response to therapy...
Mon Apr 08, 2019 03:00
Abstract Purpose NADPH oxidase 5 (NOX5), the main isoform of NOX in spermatozoa, has been recognized as the main active generators of reactive oxygen species (ROS), including superoxide anion (O 2−.) and hydrogen peroxide (H2O2). ROS have been shown to play important roles in many physiological and pathological conditions in spermatozoa. The present study aims to investigate the alterations of NOX5 protein expression...
Mon Apr 08, 2019 03:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: i-iv
Sat Apr 06, 2019 03:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 311-320
Wed Mar 27, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 321-326
Fri Mar 15, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 327-334
Tue Mar 12, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 335-340
Wed Mar 13, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 341-346
Wed Mar 13, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 347-354
Fri Mar 15, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 355-361
Sat Mar 23, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 369-374
Fri Mar 15, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 383-389
Wed Mar 13, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 391-397
Fri Mar 15, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 399-401
Fri Mar 15, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 415-419
Wed Mar 20, 2019 02:00
Journal Name: Journal of Pediatric Endocrinology and MetabolismVolume: 32Issue: 4Pages: 421-428
Wed Mar 13, 2019 02:00
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