Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Πέμπτη 6 Ιουνίου 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


How plastics are compromising the health of children Wednesday, June 05, 2019 by: Isabelle Z. Tags: badfood, badhealth, badpollution, BPA, chemicals, child...
How plastics are compromising the health of childrenWednesday, June 05, 2019 by: Isabelle Z. Tags: badfood, badhealth, badpollution, BPA, chemicals, child development, child health, disease causes, Endocrine disruptors, environment, microplastics, plastics, PVC, toxic ingredients, toxins370VIEWS(Natural News) Parents have a seemingly endless to-do list, and modern conveniences can save a lot of time and hassle. While it's easy to see the upsides of plastic goods – with their low prices, wide availability,...
Αλέξανδρος Γ. Σφακιανάκης
4m
6ο Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Άνοιας | 14-17 Νοεμβρίου 2019 Ψυχο-γραφήματα by Ρεβέκκα...
6ο Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Άνοιας | 14-17 Νοεμβρίου 2019Ψυχο-γραφήματα by Ρεβέκκα Τσοχαντάρη - 1h ago Preview    AUTO POST  SAVE TO EVERNOTE"Master Classes in Dementia 2019"Ελληνική Εταιρεία Άνοιας14-17 ΝΟΕΜΒΡΙΟΥ 2019Portaria Hotel, Πορταριά ΠηλίουΟργάνωση: ΟΝΕ ΤΟ ΟΝΕ Α.Ε., ΝΙΚΗΣ 16, 10557 ΑΘΗΝΑThe post 6ο Πανελλήνιο Συνέδριο Ελληνικής Εταιρείας Άνοιας | 14-17 Νοεμβρίου 2019 appeared first on Ψυχο-γραφήματα.Read Full Article Visit website
Αλέξανδρος Γ. Σφακιανάκης
19m
Feeding the Me Monster Psychology Today Blogs by Jack Schafer Ph.d. - 1h ago Preview     AUTO POST ...
Feeding the Me MonsterPsychology Today Blogs by Jack Schafer Ph.d. - 1h ago Preview    AUTO POST  SAVE TO EVERNOTESelfies are snacks for the Me MonsterRead Full ArticleVisit websiteAntonio Guillem/123RFSource: Antonio Guillem/123RFThe Me Monster is nibbling at the edge of our social fabric. Society is no longer a collective we, but, rather, a collection of individual me(s). Everybody does what they think is right in their own eyes. Truth as a global principle no longer exists. My truth has replaced...
Αλέξανδρος Γ. Σφακιανάκης
19m
It's time for men to step up and share responsibility for birth control | Moira Donegan Society:...
It's time for men to step up and share responsibility for birth control | Moira DoneganSociety: Health | guardian.co.uk by Moira Donegan - 59m ago Preview    AUTO POST  SAVE TO EVERNOTEWhy does the onus of birth control always fall on women? With access to contraception and abortion under threat, men must do their partA woman who doesn't want to get pregnant can take a pill, or wear a patch or insert a hormone-filled ring into her vagina. She can have hormone-secreting implants inserted into her...
Αλέξανδρος Γ. Σφακιανάκης
21m
Putting the Glam in Mammogram The New York Times » Health by Stephanie Clifford - 49m ago Preview...
Putting the Glam in MammogramThe New York Times » Health by Stephanie Clifford - 49m ago Preview    AUTO POST  SAVE TO EVERNOTEClinics are trying to improve the experience to get women to show up for regular appointments.Read Full Article Visit websiteBy Stephanie CliffordJune 6, 2019When Shawna Peters, a cybersecurity recruiter in St. Paul, Minn., heard about a V.I.P. night including chair massages and goody bags with mints, lip balms and pedicure accessories, she signed right up. Nevermind that...
Αλέξανδρος Γ. Σφακιανάκης
22m
How Employers Can Support Women During Postpartum Depression World of Psychology by Psych Central...
How Employers Can Support Women During Postpartum DepressionWorld of Psychology by Psych Central Guest Author - 40m ago Preview    AUTO POST  SAVE TO EVERNOTEPregnancy and childbirth are often an exciting, happy time in a family's life, but it is also an incredibly stressful time to the whole family. This becomes even more difficult when mom works.Caring for a newborn (especially the first born or a child with special needs) is a significant time commitment. This becomes more challenging as moms...
Αλέξανδρος Γ. Σφακιανάκης
25m
A Predictive Model Assessing Genetic Susceptibility Risk at Workplace International Journal of Environmental...
A Predictive Model Assessing Genetic Susceptibility Risk at WorkplaceInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph16112012Authors: Chiarella Capone Carbonari Sisto(1) Background: The study of susceptibility biomarkers in the immigrant workforce integrated into the social tissue of European host countries is always a challenge, due to high individual heterogeneity and the admixing of different ethnicities in the same workplace. These workers having distinct...
Αλέξανδρος Γ. Σφακιανάκης
2h
Influence of Body Mass Index on Gestation and Delivery in Nulliparous Women: A Cohort Study International...
Influence of Body Mass Index on Gestation and Delivery in Nulliparous Women: A Cohort StudyInternational Journal of Environmental Research and Public Health doi: 10.3390/ijerph16112015Authors: Noemí Rodríguez-Mesa Paula Robles-Benayas Yolanda Rodríguez-López Eva María Pérez-Fernández Ana Isabel Cobo-CuencaAims: To assess the influence of obesity on pregnancy and delivery in pregnant nulliparous women. Methods: A cohort, longitudinal, retrospective study was conducted in Spain with 710 women, of which...
Αλέξανδρος Γ. Σφακιανάκης
2h
The prognosis of functional limb weakness: a 14-year case-control study Brain - Advance Access -...
The prognosis of functional limb weakness: a 14-year case-control studyBrain - Advance Access - 2h ago Preview    AUTO POST  SAVE TO EVERNOTEAbstractReliable data on the prognosis of functional motor disorder are scarce, as existing studies of the prognosis of functional motor disorder are nearly all retrospective, small and uncontrolled. In this study we used a prospectively recruited, controlled cohort design to assess misdiagnosis, mortality and symptomatic and health outcome in patients with...
Αλέξανδρος Γ. Σφακιανάκης
2h
Neuronal migration disorders (NMDs)
SCN2A mutation in an infant with Ohtahara syndrome and neuroimaging findings: expanding the phenotype of neuronal migration disordersAbstractNeuronal migration disorders (NMDs) are a heterogeneous group of conditions caused by the abnormal migration of neuroblasts in the developing brain and nervous system, resulting in severe developmental impairment, intractable epilepsy and intellectual disability (Spalice et al. 2009). To date, many genes have been identified as the leading cause of migration...
Αλέξανδρος Γ. Σφακιανάκης
2h
Genetic variant rs10937405 of TP63 and susceptibility to lung cancer risk in north Indian population...
Genetic variant rs10937405 of TP63 and susceptibility to lung cancer risk in north Indian populationAbstractSeveral studies including genomewide association studies (GWASs) in diverse ethnic populations have reported a significant association of genetic variant rs10937405 of TP63 with nonsmall cell lung cancer (NSCLC). However, no data are available from any Indian population on the association of this variant with NSCLC. Using TaqMan genotyping chemistry, we conducted a case–control study involving...
Αλέξανδρος Γ. Σφακιανάκης
2h
Pure Laparoscopic Anatomical Segment V Resection Using the Extrafascial and Transfissural Glissonean...
Pure Laparoscopic Anatomical Segment V Resection Using the Extrafascial and Transfissural Glissonean ApproachAbstractBackgroundThe Glissonean approach is a widely used, effective technique for anatomical segmentectomy using an open or laparoscopic approach.1–4 In the extrafascial Glissonean approach, the deep tertiary branches of the right anterior portal pedicle may be difficult to dissect from the liver hilum.5,6 We present a pure laparoscopic anatomical segment V resection using the extrafascial...
Αλέξανδρος Γ. Σφακιανάκης
2h
Pure Laparoscopic Anatomical Segment V Resection Using the Extrafascial and Transfissural Glissonean...
Pure Laparoscopic Anatomical Segment V Resection Using the Extrafascial and Transfissural Glissonean ApproachAbstractBackgroundThe Glissonean approach is a widely used, effective technique for anatomical segmentectomy using an open or laparoscopic approach.1–4 In the extrafascial Glissonean approach, the deep tertiary branches of the right anterior portal pedicle may be difficult to dissect from the liver hilum.5,6 We present a pure laparoscopic anatomical segment V resection using the extrafascial...
Αλέξανδρος Γ. Σφακιανάκης
2h
Laparoscopic Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy (L-CRS/HIPEC) for...
Laparoscopic Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy (L-CRS/HIPEC) for Perforated Low-Grade Appendiceal Mucinous Neoplasm (LAMN II)AbstractIntroductionCytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is an established treatment for pseudomyxoma peritonei resulting from a perforated low-grade appendiceal mucinous neoplasm (LAMN II). In patients with localized disease, a laparoscopic procedure (L-CRS/HIPEC) can be undertaken.MethodsThis video...
Αλέξανδρος Γ. Σφακιανάκης
2h
Ozone pollution and asthma emergency
 department visits in Fresno, CA, USA, during the warm season (June–September) of the years 2005 to 2015: a time-stratified case-crossover analysisAbstractFresno, located at the central part of the San Joaquin Valley (SJV), CA, USA, is one of the most air-polluted cities in North America. The present time-stratified case-crossover study investigates whether short-term exposure to ozone (O3) is associated with asthma emergency departments (ED) visits during the high O3 warm seasons (June–September)...
Αλέξανδρος Γ. Σφακιανάκης
2h
Spatial patterns of conditions leading to peak O 3 concentrations revealed by clustering analysis of...
Spatial patterns of conditions leading to peak O 3 concentrations revealed by clustering analysis of modeled dataAbstractAir quality models are currently the best available tool to estimate ozone (O3) concentrations in the Metropolitan Area of Buenos Aires (MABA). While the DAUMOD-GRS has been satisfactorily evaluated against observations in the urban area, a Monte Carlo (MC) analysis showed that it is the region around the MABA, where the lack of observations impedes model testing, that concentrates...
Αλέξανδρος Γ. Σφακιανάκης
2h
Highly size-resolved characterization of water-soluble inorganic ions in submicron atmospheric particles...
Highly size-resolved characterization of water-soluble inorganic ions in submicron atmospheric particlesAbstractUp to date, few attentions have been given to the special characterization of water-soluble inorganic ions (WSIs) in the submicron atmospheric particles. In this study, to implement a highly size-resolved characterization of WSIs in the submicron atmospheric particles, ten sets of size-segregated submicron atmospheric particles were collected in Hangzhou (China) from November to December...
Αλέξανδρος Γ. Σφακιανάκης
2h
Comparison of spatial patterns of ammonia concentration and dry deposition flux between a regional...
Comparison of spatial patterns of ammonia concentration and dry deposition flux between a regional Eulerian chemistry-transport model and a local Gaussian plume modelAbstractAgricultural activities are the principal sources of ammonia (NH3) emitted into the atmosphere. High ammonia deposition flux may impact sensitive ecosystems. Regional models of NH3 dispersion, transport and deposition may under- or overestimate NH3 fluxes. We compared NH3 dry deposition fluxes simulated with local and regional...
Αλέξανδρος Γ. Σφακιανάκης
2h
Household fine particulate matter (PM 2.5 ) concentrations from cooking fuels
: the case in an urban setting, Wolaita Sodo, EthiopiaAbstractHousehold air pollution from biomass fuel is a main cause of health problem in Ethiopia, since 93% of households use solid fuel for cooking. Household air pollution studies are limited in Ethiopia. Therefore, we attempted to determine the level of household fine particulate matter concentrations from cooking fuels in Wolaita Sodo town, Ethiopia. A cross-sectional study design was used to measure particulate matter (PM2.5) in 109 kitchens...
Αλέξανδρος Γ. Σφακιανάκης
2h
Fragranced consumer products and effects on asthmatics: an international population-based study Abstract...
Fragranced consumer products and effects on asthmatics: an international population-based studyAbstractAsthma is an international concern, with risks linked to air pollutants. Fragranced consumer products, such as air fresheners and cleaning supplies, have been associated with health problems such as asthma attacks and breathing difficulties. This study investigates the health and societal effects of fragranced products on asthmatics in four countries: United States, Australia, United Kingdom, and...
Αλέξανδρος Γ. Σφακιανάκης
2h
Minimally invasive treatment of pediatric head and neck dermoids: percutaneous drainage and radiofrequency...
Minimally invasive treatment of pediatric head and neck dermoids: percutaneous drainage and radiofrequency coblationAbstractBackgroundDermoids are common benign head and neck cysts in children containing a variety of different skin elements. Current standard treatment is surgical removal that sometimes requires extensive dissection to ensure complete resection and often leaves unwanted facial scarring. A minimally invasive treatment alternative should offer a similar rate of success with a decrease...
Αλέξανδρος Γ. Σφακιανάκης
2h
Characterisation of computed tomography angiography findings in paediatric patients with heterotaxy...
Characterisation of computed tomography angiography findings in paediatric patients with heterotaxyAbstractBackgroundHeterotaxy refers to the abnormal arrangement of organs across the left–right axis and is typically associated with complex cardiovascular malformations.ObjectiveTo characterise the range of cardiac and extracardiac CT angiography findings in children with heterotaxy using the latest nomenclature consensus and to compare the different types of isomerism.Materials and methodsWe retrospectively...
Αλέξανδρος Γ. Σφακιανάκης
2h
Cancer-associated cerebral infarction during direct oral anticoagulant treatment in cancer patients:...
Cancer-associated cerebral infarction during direct oral anticoagulant treatment in cancer patients: a case seriesAbstractThe effect of direct oral anticoagulants (DOACs) on cancer-associated cerebral infarction (CI) is unclear. We present the clinical course of 20 consecutive patients with cancer-associated CI that developed during treatment with DOACs. The incidence rate of cancer-associated CI during the treatment with DOACs was 3.4%. The median modified Rankin scale (mRS) and Karnofsky performance...
Αλέξανδρος Γ. Σφακιανάκης
2h
Primary tumor of the ureteral stump after a radical nephrectomy for renal cell carcinoma: case report...
Primary tumor of the ureteral stump after a radical nephrectomy for renal cell carcinoma: case report and literature reviewAbstractWe report a case of ureteral stump carcinoma following a radical nephrectomy for renal cell carcinoma. A 76-year-old man was diagnosed as having ascending colon cancer and a right renal carcinoma. He was treated with partial colon resection and radical nephrectomy without lymphadenectomy. The histology was renal cell carcinoma. Three years after that surgery, he complained...
Αλέξανδρος Γ. Σφακιανάκης
2h
Simultaneous chylous ascites and chylothorax during ramucirumab plus docetaxel chemotherapy in a patient...
Simultaneous chylous ascites and chylothorax during ramucirumab plus docetaxel chemotherapy in a patient with non-small lung cell cancerAbstractA 69-year-old woman was diagnosed as having non-small cell lung cancer (adenocarcinoma, T1aN3M1b). She had no history of surgery or abdominal trauma. She was treated with ramucirumab (10 mg/kg) plus docetaxel (60 mg/m2) intravenously (RAM + DTX) every 3 weeks. Although an enhanced CT examination showed a partial tumor response after eight courses of RAM + DTX,...
Αλέξανδρος Γ. Σφακιανάκης
2h
Successful treatment of advanced gastric cancer with liver metastasis by S-1 + CDDP and S-1 therapy...
Successful treatment of advanced gastric cancer with liver metastasis by S-1 + CDDP and S-1 therapy without surgeryAbstractIt is generally reported that prognosis of patients who have unresectable gastric cancer is from 3 to 5 months with best supportive care. Despite the improvement of survival after the appearance of S-1, the outcome of treatment for advanced gastric cancer is still unfavorable. Here we present a valuable case of advanced gastric cancer with synchronous liver metastasis, which...
Αλέξανδρος Γ. Σφακιανάκης
2h
Primary small cell neuroendocrine carcinoma of adrenal gland Abstract Neuroendocrine tumors are an...
Primary small cell neuroendocrine carcinoma of adrenal glandAbstractNeuroendocrine tumors are an extremely rare form of retroperitoneum tumor. A 79-year-old man presented with abdominal pain. Computed tomography and magnetic resonance imaging revealed a 51 × 36 mm mass in the left adrenal gland. Gastrofiberscopy, colonfiberscopy and positron emission tomography were performed and showed no lesions or other malignancies. Endocrine tests were normal. Two months later, the mass had grown to 68 × 52 mm....
Αλέξανδρος Γ. Σφακιανάκης
2h
Small-cell lung carcinoma with ovarian metastasis 4 years after the first-line treatment Abstract Small-cell...
Small-cell lung carcinoma with ovarian metastasis 4 years after the first-line treatmentAbstractSmall-cell lung carcinoma rarely metastasizes to the ovary. Only few cases of this condition have been reported to date. A 42-year-old female nonsmoker was an outpatient after receiving treatment for small-cell lung carcinoma. Approximately 45 months after the first-line treatment, the pro-gastrin-releasing peptide level exhibited a gradual increase. Positron emission tomography-computed tomography revealed...
Αλέξανδρος Γ. Σφακιανάκης
2h
Radiation myelitis after durvalumab administration following chemoradiotherapy for locally advanced...
Radiation myelitis after durvalumab administration following chemoradiotherapy for locally advanced non-small cell lung cancer: an illustrative case report and review of the literatureAbstractA 69-year-old man with stage IIIB lung adenocarcinoma received durvalumab following chemoradiotherapy. The prescribed dose was 50 Gy in 2 Gy fractions, and the maximum spinal cord dose was 40 Gy. After three cycles of durvalumab, he experienced bladder and rectal disturbance, muscle weakness in the lower limbs,...
Αλέξανδρος Γ. Σφακιανάκης
2h
Pazopanib maintenance therapy after tandem high-dose chemotherapy for disseminated Ewing sarcoma Abstract...
Pazopanib maintenance therapy after tandem high-dose chemotherapy for disseminated Ewing sarcomaAbstractThe dismal prognosis of patients with disseminated Ewing sarcoma necessitates the development of novel treatment strategies. Pazopanib is an oral multi-targeted tyrosine kinase inhibitor that is active against advanced soft tissue sarcoma. However, the clinical activity and feasibility of pazopanib for treating Ewing sarcoma remain poorly understood. Moreover, clinical information on the use of...
Αλέξανδρος Γ. Σφακιανάκης
2h
The rapid improvement in visual field defect observed with weekly perimetry during intensity-modulated...
The rapid improvement in visual field defect observed with weekly perimetry during intensity-modulated radiotherapy for optic nerve sheath meningiomaAbstractDuring precision radiotherapy to treat optic nerve sheath meningioma, early improvement in visual function has been seen. This has been difficult to explain biologically. In the present study, we aimed to investigate this rapid improvement in visual function. To this end, we prospectively tested a single patient's visual field (VF) using Humphrey...
Αλέξανδρος Γ. Σφακιανάκης
2h
Hematogenous intestinal metastases from sigmoid colon cancer presenting as iliopsoas abscess and bowel...
Hematogenous intestinal metastases from sigmoid colon cancer presenting as iliopsoas abscess and bowel obstructionAbstractIntestinal metastases from colorectal cancer typically occur by intraperitoneal spread, whereas those occurring via hematogenous route are exceedingly rare. We report a case of intestinal metastases from sigmoid colon cancer that presented as iliopsoas abscess and ileus. A 78-year-old man who had undergone sigmoidectomy for sigmoid colon cancer 5 years ago was referred to our...
Αλέξανδρος Γ. Σφακιανάκης
2h
Molecular carcinogenesis of gastric cancer: Lauren classification, mucin phenotype expression, and...
Molecular carcinogenesis of gastric cancer: Lauren classification, mucin phenotype expression, and cancer stem cellsAbstractGastric cancer (GC), one of the most common human cancers, is a heterogeneous disease with different phenotypes, prognoses, and responses to treatment. Understanding the pathogenesis of GC at the molecular level is important for prognosis prediction and determining treatments. Microsatellite instability (MSI), silencing of MLH1, MGMT, and CDKN2A genes by DNA hypermethylation, KRAS mutation, APC mutation,...
Αλέξανδρος Γ. Σφακιανάκης
2h
Long-term outcomes and prognostic factors of pulmonary metastasectomy for osteosarcoma and soft tissue...
Long-term outcomes and prognostic factors of pulmonary metastasectomy for osteosarcoma and soft tissue sarcomaAbstractBackgroundThe prognostic factors of pulmonary metastasectomy in patients with osteosarcoma and soft tissue sarcoma remain controversial. The purpose of our analysis was to explore the prognostic factors and outcomes of patients with osteosarcoma and soft tissue sarcoma who underwent pulmonary metastasectomy at our institution.MethodsWe reviewed the data of 44 patients who underwent...
Αλέξανδρος Γ. Σφακιανάκης
2h
A prognostic parameter in advanced non-small cell lung cancer: the ratio of hemoglobin-to-red cell...
A prognostic parameter in advanced non-small cell lung cancer: the ratio of hemoglobin-to-red cell distribution widthAbstractBackgroundThis study aims to investigate the prognostic value of the ratio of hemoglobin–RDW (HRR) at diagnosis, in terms of overall survival (OS) and progression-free survival in patients with advanced non-small cell lung cancer (NSCLC).MethodsPatients with metastatic NCCLC who attended two separate medical oncology clinics between April 2013 and December 2017 were retrospectively...
Αλέξανδρος Γ. Σφακιανάκης
2h
Comparative assessment of prognostic outcomes between first-generation antiandrogens and novel androgen-receptor-axis-targeted...
Comparative assessment of prognostic outcomes between first-generation antiandrogens and novel androgen-receptor-axis-targeted agents in patients with non-metastatic castration-resistant prostate cancerAbstractBackgroundTo compare the prognostic outcomes between first-generation antiandrogen (FGA) and novel androgen-receptor-axis-targeted agent (ARATA) as first-line therapy in patients with non-metastatic castration-resistant prostate cancer (nmCRPC).MethodsThis study retrospectively included a total...
Αλέξανδρος Γ. Σφακιανάκης
2h
Discrimination between breast invasive ductal carcinomas and benign lesions by optimizing quantitative...
Discrimination between breast invasive ductal carcinomas and benign lesions by optimizing quantitative parameters derived from dynamic contrast-enhanced MRI using a semi-automatic methodAbstractBackgroundTo propose a semi-automatic method for distinguishing invasive ductal carcinomas from benign lesions on breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI).Methods142 cases were included. In the conventional method, the region of interest for a breast lesion was drawn manually and...
Αλέξανδρος Γ. Σφακιανάκης
2h
Inflammation–nutrition score predicts prognosis of patients with resectable hepatocellular carcinoma...
Inflammation–nutrition score predicts prognosis of patients with resectable hepatocellular carcinomaAbstractBackgroundVarious inflammation-based prognostic scores have been associated with poor survival in patients with hepatocellular carcinoma (HCC).MethodsData were collected retrospectively from 674 HCC patients who underwent curative resection. The correlation between INS (inflammation–nutrition score), BCLC (Barcelona Clinic Liver Cancer) stage and inflammatory indices and overall survival (OS)...
Αλέξανδρος Γ. Σφακιανάκης
2h
Biweekly S-1 plus oxaliplatin (SOX) reintroduction in previously treated metastatic colorectal cancer...
Biweekly S-1 plus oxaliplatin (SOX) reintroduction in previously treated metastatic colorectal cancer patients (ORION 2 study): a phase II study to evaluate the efficacy and safetyAbstractBackgroundThe reintroduction of oxaliplatin as a third-or-later-line regimen has been a promising option for patients with metastatic colorectal cancer (mCRC) who previously received chemotherapy including oxaliplatin. In this single-arm phase II study, we evaluated the efficacy of biweekly SOX, which is the combination...
Αλέξανδρος Γ. Σφακιανάκης
2h
Oncologic and reproductive outcomes of cystectomy as a fertility-sparing treatment for early-stage epithelial...
Oncologic and reproductive outcomes of cystectomy as a fertility-sparing treatment for early-stage epithelial ovarian cancerAbstractBackgroundFertility-sparing surgery (FSS) has mainly been chosen for young women with ovarian-confined/well-differentiated epithelial ovarian cancer (EOC). In general, FSS consists of at least conservation of contralateral ovary and the uterus with a staging surgery. However, information on the clinical outcome in women who underwent cystectomy as a fertility-preserving...
Αλέξανδρος Γ. Σφακιανάκης
2h
Assessment of the skin tissue structure using an ultrasonic diagnostic imaging device in patients undergoing...
Assessment of the skin tissue structure using an ultrasonic diagnostic imaging device in patients undergoing open surgeryFumiya Oohashi  Takashi Suto  Hiroki Matsui  Ken Shirabe  Yoko UchidaFirst published: 29 May 2019 https://doi.org/10.1111/srt.12727AbstractBackgroundPerioperative skin injury is a major issue; therefore, several preventative measures have been developed. However, no previous studies have visualized the effects of stromal edema caused by surgical invasion of skin tissue, and therefore,...
Αλέξανδρος Γ. Σφακιανάκης
2h
Data augmentation in dermatology image recognition using machine learning 1st Lt. Pushkar Aggarwal...
Data augmentation in dermatology image recognition using machine learning1st Lt. Pushkar AggarwalFirst published: 29 May 2019 https://doi.org/10.1111/srt.12726Read the full textePDFPDFTOOLS SHAREAbstractBackgroundEach year in the United States, over 80 million people are affected by acne, atopic dermatitis, rosacea, psoriasis, and impetigo. Artificial intelligence and machine learning could prove to be a good tool for assisting in the diagnosis of dermatological conditions. The objective of this...
Αλέξανδρος Γ. Σφακιανάκης
2h
A preliminary study on ultrasound techniques applied to cicatricial alopecia Zeynep Gizem Kaya İslamoğlu ...
A preliminary study on ultrasound techniques applied to cicatricial alopeciaZeynep Gizem Kaya İslamoğlu  Emine UysalFirst published: 29 May 2019 https://doi.org/10.1111/srt.12725Read the full textePDFPDFTOOLS SHAREAbstractBackgroundCicatricial alopecia (CA) is a group of disorder characterized by permanent destruction of the hair follicle. Shear wave elastography (SWE) and superb microvascular imaging (SMI) are noninvasive ultrasonic techniques which evaluate thickness, stiffness, and vascular index...
Αλέξανδρος Γ. Σφακιανάκης
2h
Color Doppler as a tool for correlating vascularization and pain in hidradenitis suppurativa lesions...
Color Doppler as a tool for correlating vascularization and pain in hidradenitis suppurativa lesionsGianluca Nazzaro  Emanuela Passoni  Paolo Calzari  Mauro Barbareschi  Simona Muratori  Stefano Veraldi  Angelo Valerio MarzanoFirst published: 29 May 2019 https://doi.org/10.1111/srt.12729Read the full textePDFPDFTOOLS SHAREAbstractBackgroundHidradenitis suppurativa (HS) is a debilitating, chronic‐relapsing, inflammatory skin disease of apocrine gland‐bearing skin, presenting with nodules, abscesses,...
Αλέξανδρος Γ. Σφακιανάκης
2h
Oncology
Oncologic and reproductive outcomes of cystectomy as a fertility-sparing treatment for early-stage epithelial ovarian cancerAbstractBackgroundFertility-sparing surgery (FSS) has mainly been chosen for young women with ovarian-confined/well-differentiated epithelial ovarian cancer (EOC). In general, FSS consists of at least conservation of contralateral ovary and the uterus with a staging surgery. However, information on the clinical outcome in women who underwent cystectomy as a fertility-preserving...
Αλέξανδρος Γ. Σφακιανάκης
2h
Cancer
Hematogenous intestinal metastases from sigmoid colon cancer presenting as iliopsoas abscess and bowel obstructionAbstractIntestinal metastases from colorectal cancer typically occur by intraperitoneal spread, whereas those occurring via hematogenous route are exceedingly rare. We report a case of intestinal metastases from sigmoid colon cancer that presented as iliopsoas abscess and ileus. A 78-year-old man who had undergone sigmoidectomy for sigmoid colon cancer 5 years ago was referred to our...
Αλέξανδρος Γ. Σφακιανάκης
2h
Effect of Mechanical Tension on the circRNA Expression Profile of Human Skin Tissue Liu, Zheng, MD*;...
Effect of Mechanical Tension on the circRNA Expression Profile of Human Skin TissueLiu, Zheng, MD*; Liu, Wei, MD†; Fan, Jincai, MD, PhD*; Liu, Liqiang, MD*; Tian, Jia, MD*; Gan, Cheng, MD*; Jiao, Hu, MD*; Yang, Zengjie, MD*Journal of Craniofacial Surgery: June 3, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/SCS.0000000000005592Brief Clinical Studies: PDF OnlyBUYPAPAbstractAuthor InformationArticle MetricsSkin soft tissue dilatation has emerged as one of the most prominent methods...
Αλέξανδρος Γ. Σφακιανάκης
2h
Pediatric Radiology
Characterisation of computed tomography angiography findings in paediatric patients with heterotaxyAbstractBackgroundHeterotaxy refers to the abnormal arrangement of organs across the left–right axis and is typically associated with complex cardiovascular malformations.ObjectiveTo characterise the range of cardiac and extracardiac CT angiography findings in children with heterotaxy using the latest nomenclature consensus and to compare the different types of isomerism.Materials and methodsWe retrospectively...
Αλέξανδρος Γ. Σφακιανάκης
2h
Air Quality, Atmosphere ,Health
Fragranced consumer products and effects on asthmatics: an international population-based studyAbstractAsthma is an international concern, with risks linked to air pollutants. Fragranced consumer products, such as air fresheners and cleaning supplies, have been associated with health problems such as asthma attacks and breathing difficulties. This study investigates the health and societal effects of fragranced products on asthmatics in four countries: United States, Australia, United Kingdom, and...
Αλέξανδρος Γ. Σφακιανάκης
2h
Surgical Oncology
ASO Author Reflections: An Optimal Biological Model for Successful Drug DiscoveryASO Author Reflections: Surgical Treatment for Male Breast Cancer in the Modern EraLaparoscopic Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy (L-CRS/HIPEC) for Perforated Low-Grade Appendiceal Mucinous Neoplasm (LAMN II)AbstractIntroductionCytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) is an established treatment for pseudomyxoma peritonei resulting from a perforated...
Αλέξανδρος Γ. Σφακιανάκης
2h
Removal of rIVCFs before discharge once patients are appropriately anticoagulated is a safe strategy to improve retrieval rates.Severely injured trauma patients are at high risk of developing deep venous thombosis (DVT) and pulmonary emboli (PE), and may have contraindications to prophylactic or therapeutic anticoagulation. Retrievable inferior vena cava filters (rIVCFs) are used to act as a mechanical obstruction to prevent PE in high risk populations and those with DVT who cannot be anticoagulated.
Removal of Retrievable Inferior Vena Cava Filters before dischargeIs it associated with increased incidence of pulmonary embolism?Robbins, Justin M., BS1; Garwe, Tabitha, PhD, MPH2,3; McCarthy, Cullen K., MD2; Sarwar, Zoona, MS2; Gonzalez, Robert A., BS1; Zander, Tyler, BS1; Jalla, Aditi N., MD2; Conner, Keri S., DO4; Stewart, Kenneth, PhD, MPH2; Albrecht, Roxie M., MD2Journal of Trauma and Acute Care Surgery: June 3, 2019 - Volume Publish Ahead of Print - Issue - pdoi: 10.1097/TA.00000000000023952019...
Αλέξανδρος Γ. Σφακιανάκης
2h
Genetics
Translation initiation codon (ATG) or SCoT markers-based polymorphism study within and across various Capsicum accessions: insight from their amplification, cross-transferability and genetic diversityAbstractBeing an economical and nutritional crop, Capsicum appeases people's peppery taste and is found to be widely distributed all over the world having vast diversity. In the present study, genetic polymorphism, cross transferability (CT) and genetic diversity were examined among the 54 different...
Αλέξανδρος Γ. Σφακιανάκης
2h
NEJM Resident E-Bulletin
Adding Azithromycin to Seasonal Malaria Chemoprevention: Does the addition of azithromycin to seasonal malaria chemoprevention reduce overall childhood mortality and morbidity?Prevention of Opioid Overdose: When is coprescription of naloxone indicated for a patient receiving opioids?FEATURED ONLINE HIGHLIGHTCASE CHALLENGEA Woman with Abdominal Pain and FeverA 38-year-old woman with a history of Crohn's disease was admitted to the hospital because of abdominal pain and fever. Despite appropriate medical...
Αλέξανδρος Γ. Σφακιανάκης
2h
Effect of Adding Azithromycin to Seasonal Malaria Chemoprevention Daniel Chandramohan, Ph.D., Alassane...
Effect of Adding Azithromycin to Seasonal Malaria ChemopreventionDaniel Chandramohan, Ph.D., Alassane Dicko, M.D., Issaka Zongo, Ph.D., Issaka Sagara, M.D., Matthew Cairns, Ph.D., Irene Kuepfer, Ph.D., Modibo Diarra, M.D., Amadou Barry, M.D., Amadou Tapily, M.D., Frederic Nikiema, M.D., Serge Yerbanga, Ph.D., Samba Coumare, M.D., et al.ArticleFigures/MediaMetrics19 References1 Citing ArticleComment Comments  open through June 12, 2019AbstractBACKGROUNDMass administration of azithromycin for trachoma...
Αλέξανδρος Γ. Σφακιανάκης
2h
Mandatory Measles Vaccination in New York City — Reflections on a Bold Experiment Julie D. Cantor, M.D.,...
Mandatory Measles Vaccination in New York City — Reflections on a Bold ExperimentJulie D. Cantor, M.D., J.D.ArticleFigures/MediaMetrics5 ReferencesAudio InterviewDigital Object ThumbnailInterview with Dr. Anthony Fauci on troubling increases in measles cases in the United States and globally. (12:11)Download"Experience should teach us to be most on our guard to protect liberty when the government's purposes are beneficent."— Justice Louis D. BrandeisThough a vaccine has been available for more than...
Αλέξανδρος Γ. Σφακιανάκης
2h
Abdominal Pain and Fever
CASE CHALLENGEA 38-Year-Old Woman with Abdominal Pain and FeverCaseThe case description for a Case Records of the Massachusetts General Hospital appears below. What is the diagnosis? What diagnostic test is most likely to be helpful? Cast your vote on the diagnosis and submit a comment about what diagnostic test is indicated. The correct diagnosis, along with the full description of the case and the procedures performed, will be published in the June 20, 2019, issue of the Journal.A 38-year-old woman...
Αλέξανδρος Γ. Σφακιανάκης
2h
A 66-year-old man presented to the emergency department with a 3-day history of cough, congestion, and...
A 66-year-old man presented to the emergency department with a 3-day history of cough, congestion, and pain in his chest and on the left side of his abdomen. What is the abnormality noted incidentally on chest radiograph and computed tomography of the abdomen?Tuberculosis Sinus solitus Lymphoma Situs inversus totalis Sarcoidosis SUBMITSee how others chose
Αλέξανδρος Γ. Σφακιανάκης
2h
Allowing Adolescents to Weigh Benefits and Burdens of High-stakes Therapies Kriti Puri, Janet Malek,...
Allowing Adolescents to Weigh Benefits and Burdens of High-stakes TherapiesKriti Puri, Janet Malek, Caridad Maylin de la Uz, John Lantos, Antonio Gabriel Cabrera, Ernest FrugéPediatricsJune 2019Ethics RoundsAbstractWe present the case of a girl aged 17 years and 10 months who has a strong family history of long QT syndrome and genetic testing confirming the diagnosis of long QT syndrome in the patient also. She was initially medically treated with β-blocker therapy; however, after suffering 1 episode...
Αλέξανδρος Γ. Σφακιανάκης
2h
Infants ≤60 days old with fever by history only, a normal urinalysis result, and an absolute neutrophil count <5185 cells per μL have a low probability of invasive bacterial infection (IBI)
A Prediction Model to Identify Febrile Infants ≤60 Days at Low Risk of Invasive Bacterial InfectionPaul L. Aronson, Veronika Shabanova, Eugene D. Shapiro, Marie E. Wang, Lise E. Nigrovic, Christopher M. Pruitt, Adrienne G. DePorre, Rianna C. Leazer, Sanyukta Desai, Laura F. Sartori, Richard D. Marble, Sahar N. Rooholamini, Russell J. McCulloh, Christopher Woll, Fran Balamuth, Elizabeth R. Alpern, Samir S. Shah, Derek J. Williams, Whitney L. Browning, Nipam Shah, Mark I. Neuman, for the Febrile Young...
Αλέξανδρος Γ. Σφακιανάκης
2h
A Prediction Model to Identify Febrile Infants ≤60 Days at Low Risk of Invasive Bacterial Infection...
A Prediction Model to Identify Febrile Infants ≤60 Days at Low Risk of Invasive Bacterial InfectionPaul L. Aronson, Veronika Shabanova, Eugene D. Shapiro, Marie E. Wang, Lise E. Nigrovic, Christopher M. Pruitt, Adrienne G. DePorre, Rianna C. Leazer, Sanyukta Desai, Laura F. Sartori, Richard D. Marble, Sahar N. Rooholamini, Russell J. McCulloh, Christopher Woll, Fran Balamuth, Elizabeth R. Alpern, Samir S. Shah, Derek J. Williams, Whitney L. Browning, Nipam Shah, Mark I. Neuman, for the Febrile Young...
Αλέξανδρος Γ. Σφακιανάκης
2h
Evaluation of wound fluid biomarkers to determine healing in adults with venous leg ulcers: A prospective...
Evaluation of wound fluid biomarkers to determine healing in adults with venous leg ulcers: A prospective studyMichael C. Stacey DS  Steven A. Phillips MSc  Forough Farrokhyar PhD  Jillian M. Swaine BScFirst published: 25 April 2019 https://doi.org/10.1111/wrr.12723Read the full textePDFPDFTOOLS SHAREAbstractClinical practice guidelines recommend using repeated wound surface area measurements to determine if a chronic ulcer is healing. This results in delays in determining the healing status. This...
Αλέξανδρος Γ. Σφακιανάκης
3h
Hemocompatibility of different burn wound dressings Markus Denzinger MD  Manuel Held MD  Hanna Scheffler ...
Hemocompatibility of different burn wound dressingsMarkus Denzinger MD  Manuel Held MD  Hanna Scheffler  Hanna Haag  Andreas K. Nussler PhD Hans Peter Wendel PhD  Christian Schlensak MD  Adrien Daigeler MD  Stefanie Krajewski PhDFirst published: 30 May 2019 https://doi.org/10.1111/wrr.12739This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this...
Αλέξανδρος Γ. Σφακιανάκης
3h
A systematic review of Calendula officinalis extract for wound healing Or Givol BSc, MD  Rachel Kornhaber...
A systematic review of Calendula officinalis extract for wound healingOr Givol BSc, MD  Rachel Kornhaber RN, PhD  Denis Visentin PhD  Michelle Cleary RN, PhD  Josef Haik MD, MPH  Moti Harats MDFirst published: 30 May 2019 https://doi.org/10.1111/wrr.12737This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record....
Αλέξανδρος Γ. Σφακιανάκης
3h
Effectiveness of Biofilm‐based Wound Care System on Wound Healing in Chronic Wounds Yukie Mori RN ...
Effectiveness of Biofilm‐based Wound Care System on Wound Healing in Chronic WoundsYukie Mori RN  Gojiro Nakagami RN, PhD  Aya Kitamura RN, PhD  Takeo Minematsu PhD  Mikio Kinoshita MD  Hiraku Suga MD, PhD  Masakazu Kurita MD, PhD … See all authorsFirst published: 30 May 2019 https://doi.org/10.1111/wrr.12738This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences...
Αλέξανδρος Γ. Σφακιανάκης
3h
Regulation and function of IL‐22 in peritoneal adhesion formation after abdominal surgery Qingbo Wang ...
Regulation and function of IL‐22 in peritoneal adhesion formation after abdominal surgeryQingbo Wang  Yongming Huang  Rui Zhou  Ke Wu  Wei Li  Liang Shi  Zefeng Xia  Kaixiong Tao  Guobin Wang  Geng WangFirst published: 30 May 2019 https://doi.org/10.1111/wrr.12740This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version...
Αλέξανδρος Γ. Σφακιανάκης
3h
A phytotoxic impact of phenolic compounds in olive oil mill wastewater on fenugreek " Trigonella foenum-graecum...
A phytotoxic impact of phenolic compounds in olive oil mill wastewater on fenugreek " Trigonella foenum-graecum "AbstractThe objective of this study is the determination of the chemical structure of nine phenolic molecules responsible for the phytotoxic action on the germination of the plant species "Trigonella foenum-graecum". The phytotoxic action was evaluated by calculating the germination index of the plant species for a period of 5 days of incubation. The analysis of the physicochemical properties...
Αλέξανδρος Γ. Σφακιανάκης
3h
Investigating the effect of several factors on concentrations of bioaerosols in a well-ventilated hospital...
Investigating the effect of several factors on concentrations of bioaerosols in a well-ventilated hospital environmentAbstractThis study characterized and quantified the bacterial and fungal bioaerosols in nine wards of the Razavi Hospital (Mashhad, Iran) that is equipped with an advanced heating, ventilating, and air conditioning (HVAC) system including HEPA filters for air cleaning. In this study, 432 samples were taken from the indoor air of multiple hospital wards during the morning and afternoon...
Αλέξανδρος Γ. Σφακιανάκης
3h
Optimization and validation of headspace solid-phase microextraction method coupled with gas chromatography–triple...
Optimization and validation of headspace solid-phase microextraction method coupled with gas chromatography–triple quadrupole tandem mass spectrometry for simultaneous determination of volatile and semi-volatile organic compounds in coking wastewater treatment plantAbstractIndustrial wastewater could be an important source for the emission of volatile (VOCs) and semi-volatile organic compounds (SVOCs), but little is known about it. In this study, a method for the identification and quantitation of...
Αλέξανδρος Γ. Σφακιανάκης
3h
Spatial distribution and ecological risk assessment of trace metals in surface sediments of Lake Qaroun,...
Spatial distribution and ecological risk assessment of trace metals in surface sediments of Lake Qaroun, EgyptAbstractA suite of trace metals was determined in twenty surface sediments collected from Lake Qaroun, which is designated as a natural reserve in 1989 to examine their spatial distribution and their potential environmental impact on the lake. Contamination factor (Cf), enrichment factor (EF), geoaccumulation index (Igeo), and pollution load index (PLI) are applied to evaluate the quality...
Αλέξανδρος Γ. Σφακιανάκης
3h
Heavy metal accumulation in surface sediments of the Ganga River (India): speciation, fractionation,...
Heavy metal accumulation in surface sediments of the Ganga River (India): speciation, fractionation, toxicity, and risk assessmentAbstractWe investigated the distribution of different fractions of eight heavy metals (Zn, Cr, Cu, Pb, Cd, Ni, Fe, and Mn) in the bed sediment of the Ganga River. The study was conducted during summer low flow (March to June 2017) considering a 285-km middle stretch of the Ganga River between the Allahabad upstream and the Varanasi downstream. To assess the metal levels...
Αλέξανδρος Γ. Σφακιανάκης
3h
Distribution, toxicity, and origins of polycyclic aromatic hydrocarbons in soils in Ulsan, South Korea...
Distribution, toxicity, and origins of polycyclic aromatic hydrocarbons in soils in Ulsan, South KoreaAbstractThis study was conducted to investigate the concentrations, distributions, toxicities, and sources of polycyclic aromatic hydrocarbons (PAHs) in the soils from different areas in Ulsan, South Korea. Samples were collected from 41 sites, including a waste treatment facilities area (WA), traffic facilities area (TA), child playground area (CA), industrial area (IA), railroad facilities area...
Αλέξανδρος Γ. Σφακιανάκης
3h
Environmental Monitoring and Assessment
Distribution, toxicity, and origins of polycyclic aromatic hydrocarbons in soils in Ulsan, South KoreaAbstractThis study was conducted to investigate the concentrations, distributions, toxicities, and sources of polycyclic aromatic hydrocarbons (PAHs) in the soils from different areas in Ulsan, South Korea. Samples were collected from 41 sites, including a waste treatment facilities area (WA), traffic facilities area (TA), child playground area (CA), industrial area (IA), railroad facilities area...
Αλέξανδρος Γ. Σφακιανάκης
3h
Healthy and Safe Swimming
Español (Spanish)Pools, hot tubs/spas, and water playgrounds are great places to have fun, be active, or just relax. Learn how to stay healthy and safe when in the water this summer!Swimming is one of the most popular sports activities in the United States. Just 2.5 hours of physical activity per week, including water-based activity, has health benefits, no matter our age.As with any form of physical activity, we increase the health benefits when we each do our part to decrease the risks of illness...
Αλέξανδρος Γ. Σφακιανάκης
3h

Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182
6948891480

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