Pediatric Drugs

Vancomycin Use in a Paediatric Intensive Care Unit of a Tertiary Care Hospital

Abstract Background Vancomycin is one of the commonly used anti-microbial drugs in intensive care units (ICUs). Guidelines recommend maintaining therapeutic trough levels of vancomycin (10–20 mg/L). The success of achieving the recommended therapeutic concentration of vancomycin is influenced by several factors, and this is even more complex in children, particularly those admitted in the ICU. Hence, we carried out the present study in children...

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Purified Cannabidiol for Treatment of Refractory Epilepsies in Pediatric Patients with Developmental and Epileptic Encephalopathy

Abstract Background A pharmaceutical grade formulation of cannabidiol (CBD) has been approved for the treatment of Dravet syndrome and Lennox-Gastaut syndrome; however, this formulation is not yet available to patients outside the USA. In addition, CBD is thought to have broad anti-seizure properties that may be beneficial for other types of intractable epilepsy. Objective ...

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Safety and Tolerability of Antipsychotic Medication in Individuals with Autism Spectrum Disorder: A Systematic Review and Meta-Analysis

Abstract Background Antipsychotic medication is a commonly prescribed drug class in individuals with autism spectrum disorder (ASD). However, the safety of these agents has not been fully assessed. Objective Our objective was to investigate the safety and tolerability profile of antipsychotics in individuals with ASD. ...

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Comparison of Quality of Life, Depression, Anxiety, Suicide, Social Anxiety and Obsessive–Compulsive Symptoms Between Adolescents with Acne Receiving Isotretinoin and Antibiotics: A Prospective, Non-randomised, Open-Label Study

Abstract Background The effects of isotretinoin on suicide, social anxiety and obsessive–compulsive symptoms in adolescents with acne have not been sufficiently investigated. Objective This study aimed to evaluate the quality of life, depression, anxiety, suicide, social anxiety, and obsessive–compulsive symptoms of adolescents receiving systemic...

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Correction to: Medical Options for the Adjuvant Treatment and Management of Pediatric Melanoma

Study NCT01519323 (A study of vemurafenib in pediatric patients with stage IIIC or stage IV melanoma harbouring BRAFV600 mutations) was included in a table listing ongoing clinical trials of adjuvant therapies for pediatric melanoma (Table 1) in error. The study was in fact closed early due to low enrollment as correctly noted in section 4 of the article.

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Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182

6948891480

alsfakia@gmail.com