Transungual Excision of Glomus Tumors: A Treatment and Quality of Life StudyBACKGROUND Glomus tumors are rare benign painful tumors, frequently found in the subungual region. Complete surgical excision is essential for relief of symptoms. The main postoperative complications are tumor recurrence and nail dystrophy. OBJECTIVE To evaluate the long-term outcome and the impact on quality of life (QoL) of glomus tumors after a transungual approach. MATERIALS AND METHODS A retrospective cohort study was...
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Validation of an Oral Disease Severity Score (ODSS) tool for use in oral mucous membrane pemphigoidM Ormond H McParland P Thakrar A N A Donaldson M Andiappan R J Cook M E Escudier J Higham E Hullah R McMillan J Taylor P J Shirlaw S J Challacombe J F SetterfieldFirst published: 30 September 2019 https://doi.org/10.1111/bjd.18566This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading...
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Combined Tumors in Hematolymphoid Neoplasms: Case Series of Histiocytic and Langerhans Cell Sarcomas Arising From Low-Grade B-Cell LymphomaShow lessStephanie L Skala, Jing C Ye, Jennifer Stumph, William R Macon, Frances R Quinones, Vadim Khachaturov, Rhett P Ketterling, Rajan DewarFirst Published September 29, 2019 Case Reporthttps://doi.org/10.1177/2632010X19878410Article information AbstractWe report an index case of histiocytic sarcoma arising in a 70-year-old patient with long-standing chronic...
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Right Atrium Blood Cyst and Calcified Kernel in an Adult , Behnam Shakerian, Mohammad JebelliFirst Published September 29, 2019 Case Reporthttps://doi.org/10.1177/1179547619870807Article information AbstractAmong benign cardiac tumors, cardiac blood cysts are rare. These congenital lesions may develop in any heart's cavities and they are not often seen in adults. The present article is a report of a right atrium blood cyst and calcified kernel in an adult case.Keywords Blood cyst, cardiac, calcified...
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Hypercholesterolemia Due to Lipoprotein X: Case Report and Thematic ReviewShow lessLaura Kattah, Andrés Gómez, Sebastián Gutiérrez, Kathalina Puerto, Eiman D Moreno-Pallares, Andrés Jaramillo, Carlos O MendivilFirst Published September 29, 2019 Case Reporthttps://doi.org/10.1177/1179551419878687Article information AbstractThe liver is a key organ in lipid and lipoprotein metabolism, hence hepatic diseases often manifest as lipid disturbances. Cholestatic liver diseases are frequently associated...
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British Journal of Dermatology, Early View Online Version of Record before inclusion in an issue ...
British Journal of Dermatology,Early ViewOnline Version of Record before inclusion in an issueEditorialThe pharmacology of itchJ.R. Ingram, A. AhluwaliaVersion of Record online: 03 October 2019CommentaryConsensus definitions of disease activity in hidradenitis suppurativa: crossing the semantic gapK. Navrazhina, J.W. FrewVersion of Record online: 03 October 2019 Open AccessGeneral DermatologyGrading immunohistochemical markers p16INK4a and HPV E4 identifies productive and transforming lesions caused...
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DERMATO MAG , Volume 7, numéro 3, 2019Découvrez le sommaire du numéro 3 - 2019 de votre revue.Très bonne lecture !Si vous avez égaré vos codes d'accès pour consulter les articles en ligne, pensez à la fonction Problèmes de connexion ? SOMMAIRE :ÉDITORIALLes flux de patients en dermatologie !Christian DerancourtArticle offertEN DIRECT> Le mot du président de la FFFCEDVJean-François Seï> Le mot de la secrétaire générale de la FFFCEDVÈve Pépin> ELSA : étude épidémiologique en milieu libéral :...
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Broncho pneumopathie chronique obstructive (BPCO) du sujet âgé :l'éditorial par le Pr Gilles BerrutChez les personnes âgées, la BPCO est la cause la plus fréquente de pathologies chroniques du sujet âgé, et lorsqu'elle est présente, une des causes majeures de décès prématuré. On estime qu'en 2020 la BPCO passerait au 5e rang des pathologies de la personne âgée et au 3e rang des causes de mortalité. À côté du tabagisme, qui concerne plus souvent également les femmes, les maladies professionnelles...
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Mitochondrial dysfunction is associated with Miro1 reduction in lung epithelial cells by cigarette smoke: Publication date: Available online 5 October 2019Source: Toxicology LettersAuthor(s): Isaac K. Sundar, Krishna P. Maremanda, Irfan RahmanAbstractCigarette smoke (CS) is known to cause mitochondrial dysfunction leading to cellular senescence in lung cells. We determined the mechanism of mitochondrial dysfunction by CS in lung epithelial cells. CSE treatment differentially affected mitochondrial...
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Moderate to severe but not mild RLS is associated with greater sleep-related sympathetic autonomic activation than healthy adults without RLSPublication date: Available online 5 October 2019Source: Sleep MedicineAuthor(s): Byungjoo Jin, Allan Wang, Christopher Earley, Richard AllenAbstractIntroductionRestless legs syndrome (RLS) patients have been found to have high rates of transitory increases in the activity of the sympathetic autonomic nervous system with increases in heart rate and blood pressure....
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Impacts of sex and the estrous cycle on associations between post-fear conditioning sleep and fear memory recallPublication date: Available online 5 October 2019Source: Behavioural Brain ResearchAuthor(s): Ihori Kobayashi, Eva PolstonAbstractWomen are at greater risk than men for developing posttraumatic stress disorder (PTSD) after trauma exposure. Sleep, especially rapid-eye-movement sleep (REMS), has been considered a contributing factor to the development of PTSD symptoms through its effects...
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Risk factors associated with myasthenia gravis in thymoma patients: The potential role of thymic germinal centers: Publication date: Available online 5 October 2019Source: Journal of AutoimmunityAuthor(s): Claire MJ. Lefeuvre, Cloé A. Payet, Odessa-Maud Fayet, Solène Maillard, Frédérique Truffault, Vincent Bondet, Darragh Duffy, Vincent de Montpreville, Maria-Rosa Ghigna, Elie Fadel, Audrey Mansuet-Lupo, Marco Alifano, Pierre Validire, Dominique Gossot, Anthony Behin, Bruno Eymard, Sonia Berrih-Aknin,...
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Impact of Reduced Incubation Times on Culture and Susceptibility Testing of Urine Cultures Incubated in the BD Kiestra ReadA Compact IncubatorsPublication date: Available online 5 October 2019Source: Diagnostic Microbiology and Infectious DiseaseAuthor(s): M Desjardins, N Sant, M. Miron-Celis, J Gosal, Marie-France Jémus, E Jémus-GonzalezAbstractWe determined the impact of reducing incubation times for urine cultures incubated in BD Kiestra ReadA Compact incubators. Urine samples (n= 348) were inoculated...
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Me<sub>2</sub>SO- and serum-free cryopreservation of human umbilical cord mesenchymal stem cells using electroporation-assisted delivery of sugars: Publication date: Available online 5 October 2019Source: CryobiologyAuthor(s): Vitalii Mutsenko, Ariana Barlič, Tamara Pezić, Janja Dermol-Černe, Barbara Dovgan, Bulat Sydykov, Willem F. Wolkers, Igor I. Katkov, Birgit Glasmacher, Damijan Miklavčič, Oleksandr GryshkovAbstractCryopreservation is the universal technology used to enable long-term...
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Recyclable and highly efficient photocatalytic fabric of Fe(III)@BiVO<sub>4</sub>/cotton via thiol-ene click reaction with visible-light response in waterPublication date: Available online 5 October 2019Source: Advanced Powder TechnologyAuthor(s): Haisheng Zhang, Dan Yu, Wei Wang, Pin Gao, Lishan Zhang, Shan Zhong, Baojiang LiuAbstractIn this article, we designed a photocatalytic cotton fabric of Fe(III)@BiVO4/cotton via thiol-ene click reaction and achieved an enhanced photocatalytic...
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Stabilization and transformation of selenium during the Fe(II)-induced transformation of Se(IV)-adsorbed ferrihydrite under anaerobic conditions: Publication date: 15 February 2020Source: Journal of Hazardous Materials, Volume 384Author(s): Shaofeng Wang, Lei Lei, Danni Zhang, Guoqing Zhang, Rui Cao, Xin Wang, Jinru Lin, Yongfeng JiaAbstractSelenium (Se) is an essential nutrient for human beings at trace concentrations, but also a hazardous contaminant at high concentrations. As an important geological...
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Behavioural and neural limits in competitive decision making: The roles of outcome, opponency and observation: Publication date: Available online 5 October 2019Source: Biological PsychologyAuthor(s): Benjamin James Dyson, Ben Albert Steward, Tea Meneghetti, Lewis ForderAbstractTo understand the boundaries we set for ourselves in terms of environmental responsibility during competition, we examined a neural index of outcome valence (feedback-related negativity; FRN) in relation to an early index of...
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A real-time-based <em>in vitro</em> assessment of the oxidative antimicrobial mechanisms of the myeloperoxidase-hydrogen peroxide-halide system: Publication date: December 2019Source: Molecular Immunology, Volume 116Author(s): Janne Atosuo, Eetu SuominenAbstractMammals have evolved a special cellular mechanism for killing invading microbes, which is called the phagocytosis. Neutrophils are the first phagocytosing cells that migrate into the site of infection. In these cells, hypochlorite...
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Translational Research , Macrophage Migration Inhibitory Factor Increases Atrial Arrhythmogenesis...
Translational Research , Macrophage Migration Inhibitory Factor Increases Atrial Arrhythmogenesis through CD74 SignalingPublication date: Available online 5 October 2019Source: Translational ResearchAuthor(s): Wan-Li Cheng, Yu-Hsun Kao, Yao-Chang Chen, Yung-Kuo Lin, Shih-Ann Chen, Yi-Jen ChenAbstractMacrophage migration inhibitory factor (MIF), a pleiotropic inflammatory cytokine, is highly expressed in patients with atrial fibrillation (AF). CD74 (major histocompatibility complex, class II invariant...
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Molecules, Vol. 24, Pages 3602: Identification of Cannabis sativa L. (hemp) Retailers by Means of Multivariate Analysis of CannabinoidsMolecules, Vol. 24, Pages 3602: Identification of Cannabis sativa L. (hemp) Retailers by Means of Multivariate Analysis of Cannabinoids Molecules doi: 10.3390/molecules24193602 Authors: Sara Palmieri Marcello Mascini Antonella Ricci Federico Fanti Chiara Ottaviani Claudio Lo Sterzo Manuel Sergi In this work, the concentration of nine cannabinoids, six neutral cannabinoids...
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Interview with Tamer Mohamed of Aspect Biosystems on Advancing Tissue Therapeutics: While attending The University of British Columbia (UBC), Tamer Mohamed, along with fellow graduate student Simon Beyer, began working at the Walus Laboratory on the development of a novel microfluidics-based bioprinting platform that could be used to fabricate human tissue constructs. One of the main reasons for their innovation was to potentially replace animal models in drug testing, which are costly, time-consuming...
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Best sources of Vitamin K:World's Healthiest Foods rich invitamin KFoodCalsDRI/DV Kale361180% Spinach41987% Mustard Greens36922% Collard Greens63858% Beet Greens39774% Swiss Chard35636% Turnip Greens29588% Parsley11554% Broccoli55245% Brussels Sprouts56243%If you've read about vitamins A, B, C, D, and E, you might feel like we've missed a few vitamins as we jump over to vitamin K. But there are no vitamins F through J (at least not yet). Vitamin K is named after the German word for blood clotting...
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Antinociceptive effects of <em>Salvia divinorum</em> and bioactive salvinorins in experimental pain models in micePublication date: Available online 5 October 2019Source: Journal of EthnopharmacologyAuthor(s): Lorenzo Leonel Tlacomulco-Flores, Myrna Déciga-Campos, María Eva González-Trujano ME, Azucena Ibeth Carballo-Villalobos, Francisco PellicerAbstractEthnopharmacological relevanceSalvia divinorum Epling & Játiva is a Mexican plant used not only in rituals but also in traditional...
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The Utility of Stuttering Support Organization Conventions for Young People Who Stutter: Publication date: Available online 5 October 2019Source: Journal of Fluency DisordersAuthor(s): Hope Gerlach, Julia Hollister, Lee Caggiano, Patricia M. ZebrowskiAbstractBackgroundStuttering Support Organizations (SSOs) are places where people who stutter can share their experiences with stuttering and lend support to each other. There is evidence that SSO participation may be helpful in reducing the negative...
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Glacier extent and climate in the Maritime Alps during the Younger Dryas: Publication date: Available online 5 October 2019Source: Palaeogeography, Palaeoclimatology, PalaeoecologyAuthor(s): Matteo Spagnolo, Adriano RiboliniAbstractThis study focuses on an Egesen-stadial moraine located at 1906-1920 m asl in the NE Maritime Alps, Europe. Three moraine boulders are dated, via cosmogenic isotope analyses, to 12,490 ± 1120, 12,260 ± 1220 and 13,840 ± 1240 yr, an age compatible with the Younger Dryas...
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Motivation for information exchange in a virtual community of practice: Evidence from a Facebook group for shrimp farmersPublication date: January 2020Source: World Development, Volume 125Author(s): Guenwoo Lee, Aya SuzukiAbstractWhat is the motivation for sharing useful information among community members? In order to reveal the motivation of information exchanges, we present the case of a Facebook group, which shares common crop practices and the majority of the members are farmers. We construct...
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Tamoxifen promotes white matter recovery and cognitive functions in male mice after chronic hypoperfusion ,Sun Oct 06, 2019 19:11via Neurochemistry InternationalPublication date: Available online 5 October 2019Source: Neurochemistry InternationalAuthor(s): Yuxue Chen, Yeye Tian, Hao Tian, Qibo Huang, Yongkang Fang, Wei Wang, Yue Wan, Dengji Pan, Minjie XieAbstractCerebral white matter lesions (WMLs) induced by chronic cerebral hypoperfusion are one of the major components of stroke pathology and...
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Automated applicator digitization for high-dose-rate cervix brachytherapy using image thresholding and density-based clustering: Publication date: Available online 5 October 2019Source: BrachytherapyAuthor(s): Christopher L. Deufel, Shulan Tian, Benjamin B. Yan, Birjoo D. Vaishnav, Michael G. Haddock, Ivy A. PetersenAbstractPurposeThe purpose of the study was to develop and evaluate an automated digitization algorithm for high-dose-rate cervix brachytherapy, with the goal of reducing the duration...
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Genetic sequencing of vaccine finds entire male human genome from aborted baby: Vaccines are routinely formulated with aborted human fetal cells known as MRC-5 and WI-38. The CDC openly lists some of the vaccines that use these "human diploid" cells, including Twinrix (Hep A / Hep B), ProQuad (MMRV) and Varivax (Varicella / chicken pox). FDA-published vaccine insert sheets such as this one for Varivax also openly admit to the use of aborted human fetal cell lines such as MRC-5:The product also...
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Being happier will help you live longer, so learn how to be happierIf you could wish for just one thing, would it be happiness or a long life? Given what researchers tell us, one is likely to produce the other.CNN.com - HealthSat Oct 05, 2019 21:06Post-surgery Taylor Swift nearly has meltdown over a bananaJimmy Fallon played a video provided by Taylor Swift's mom, Andrea, on the "Tonight Show with Jimmy Fallow" that showed the superstar singer nearly reaching an emotional breaking point over a banana...
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Treating pulmonary embolism: How safe and effective are new devices?A new scientific statement identifies the risks and benefits of novel interventional devices compared to anticoagulation alone in the treatment of patients with pulmonary embolism. Authors conclude there is little data -- particularly, as it pertains to the treatment of patients with 'intermediate-risk PE' -- that suggests these interventional approaches are more safe and effective than the use of anticoagulation alone.Health &...
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JoVE: Journal of Visualized Experiments , A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene ExpressionThe fabrication process of a PDMS-based, multilayer, microfluidic device that allows in vitro transcription and translation (IVTT) reactions to be performed over prolonged periods is described. Furthermore, a comprehensive overview of the hardware and software required to automate and maintain these reactions for prolonged durations is provided.JoVE: Journal of Visualized...
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JoVE: Journal of Visualized Experiments , Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 DimerizationA native Western blot method for analyzing endogenous interferon regulatory factor 5 dimerization in the CAL-1 plasmacytoid dendritic cell line is described. This protocol can be applied to other cell lines as well.JoVE: Journal of Visualized ExperimentsSun Oct 06, 2019 22:53Fabrication and Implementation of a Reference-Free Traction Force Microscopy PlatformThis...
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bioRxiv Subject Collection: Evolutionary Biology , The effect of habitat choice on evolutionary rescue in subdivided populations [NEW RESULTS]Evolutionary rescue is the process by which a declining population successfully adapts genetically to avoid extinction. In a structured environment that deteriorates patch by patch, dispersal can substantially alter the chances of evolutionary rescue of a wild-type population not viable in deteriorated patches. Here, we investigate the effect of different...
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Ο Όμηρος παράκουσε τον χρησμό του μαντείου των Δελφών.: Σύμφωνα με τον περιηγητή Παυσανία, ο Όμηρος επισκέφθηκε το μαντείο των Δελφών για να ρωτήσει την Πυθία ποιοι ήταν οι γονείς του και η καταγωγή του.Η Πυθία απάντησε με τον εξής χρησμό: «Πατρίδα της μητέρας σου είναι η νήσος Ίος, η οποία θα σε δεχθεί όταν πεθάνεις, αλλά φυλάξου από το αίνιγμα των νεαρών παιδιών».Ο ποιητής όμως παράκουσε τον χρησμό και ταξίδεψε μέχρι την Ίο. Εκεί είδε μερικά μικρά παιδιά που ψάρευαν στην ακτή. Τα ρώτησε τι έπιασαν...
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British Journal of Oral and Maxillofacial Surgery , Use of an acrylic jig to aid orbital reconstruction after resection of a sphenoid intraosseous meningioma: a technical noteA 48-year-old woman presented to neurosurgery with proptosis of the left globe and worsening pain and swelling in the left temporal region. Her visual acuity was unaffected. A computed tomogram (CT) of her head showed a large expansile lesion that involved the left frontal, parietal, temporal, and sphenoid bones (Fig. 1 and...
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Annals of Diagnostic Pathology , Pathology in the era of "Personalized Medicine: The need to learn how to integrate multivariate immunohistochemical and "omics" data with clinicopathologic information in a clinically relevant way"Publication date: Available online 5 October 2019Source: Annals of Diagnostic PathologyAuthor(s): Alberto M. Marchevsky, Ann E. Walts, Mark R. WickAbstract"Personalized medicine" has been proposed as a new paradigm for patient care that, based on the integration of genomics...
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Hot Tub Displays at State Fair Eyed as Link to Legionnaires' Disease OutbreakMore than 100 people in North Carolina were sickened with Legionnaires' disease and Pontiac fever last month. One person died.NYT > Health02:21Addicted to Screens? That's Really a You ProblemNir Eyal, who wrote the industry manual for hooking people on tech, now has a recipe to free you — even though it was your fault to begin with.NYT > HealthSun Oct 06, 2019 16:00
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Clinical Infectious Diseases Advance Access , Characteristics of motor dysfunction in longstanding HIVAbstractBackgroundCognitive dysfunction in HIV has decreased, but milder forms of HIV-associated neurocognitive disorders (HAND) persist along with motor dysfunction. The HIV Motor Scale (HMS) is a validated tool which captures motor abnormalities on routine neurologic examination, and which is associated with cognitive impairment in HIV. In this study, we applied a modified HMS (MHMS) to a nationwide...
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British Journal of Cancer - AOP , Identification of a biomarker panel for improvement of prostate...
British Journal of Cancer - AOP , Identification of a biomarker panel for improvement of prostate cancer diagnosis by volatile metabolic profiling of urineBritish Journal of Cancer, Published online: 07 October 2019; doi:10.1038/s41416-019-0585-4Identification of a biomarker panel for improvement of prostate cancer diagnosis by volatile metabolic profiling of urineBritish Journal of Cancer - AOP02:05Tumour cell-derived debris and IgG synergistically promote metastasis of pancreatic cancer by inducing...
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How We Affect Each Other,The principle of emotion contagion holds that emotions of two or more people converge and are passed from person to person in larger groups.Psychology Today - EssentialsSun Oct 06, 2019 16:41The Vagus Nerve May Carry Serotonin Along the Gut-Brain AxisNinety percent of serotonin is produced in the gut. A new study reports that the vagus nerve may be key for transporting mood-boosting serotonin signals from the gut to the brain.Psychology Today - EssentialsSun Oct 06, 2019...
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Exosomal Transfer Of Cisplatin-Induced miR-425-3p Confers Cisplatin Resistance In NSCLC Through Activating AutophagyInternational Journal of Nanomedicine02:30Would Colloidal Gold Nanocarriers Present An Effective Diagnosis Or Treatment For Ischemic Stroke?International Journal of Nanomedicine02:18Nanodelivery and anticancer effect of a limonoid, nimbolide, in breast and pancreatic cancer cellsInternational Journal of Nanomedicine02:03
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Elderly patients with metastatic neuroendocrine tumors are undertreated and have shorter survival: The LyREMeNET study: Introduction: The incidence of neuroendocrine tumors (NETs) is rising, especially in elderly patients. The elderly cancer population present considerable challenges, yet little is known about the characteristics, treatment pattern, and outcomes of metastatic NET patients. Methods: The Lyon Real-life Evidence in Metastatic NeuroEndocrine Tumors study (LyREMeNET, NCT03863106)...
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Scientists Grow 3D Tissue Models of Human Brain TumorsSource: Science Daily - Top HealthResearchers have developed 3-dimensional human tissue culture models of pediatric and adult brain cancers in a brain-mimicking microenvironment, that includes brain-derived extracellular matrix (ECM) -- the complex network of proteins and amino acids with bound sugars that not only provides support for surrounding neural tissue, but also helps to guide cell growth and development. The development represents a...
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Microglia as Dynamic Cellular Mediators of Brain Function: Originally hypothesized to function solely as immunologic responders within the central nervous system (CNS), emerging evidence has revealed that microglia have more complex roles in normal brain development and in the context of disease. In health, microglia influence neural progenitor fate decisions, astrocyte activation, neuronal homeostasis, and synaptogenesis. In the setting of brain disease, including autism, brain tumors, and neurodegenerative...
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A Predictive Score for Determining Risk of Surgical Site Infection After Orthopaedic Trauma Surgery: Objectives: To determine factors predictive of postoperative surgical site infection (SSI) after fracture fixation and create a prediction score for risk of infection at time of initial treatment. Design: Retrospective cohort study. Setting: Level I trauma center. Patients/Participants: Study group, 311 patients with deep SSI; control group, 608 patients. Intervention: We evaluated...
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Association between the -844 G>A, HindIII C>G, and 4G/5G PAI-1 Polymorphisms and Susceptibility to Multiple Sclerosis in Western Mexican Population: Introduction. Multiple sclerosis is an inflammatory disease, where fibrin deposition and the impairment in its degradation have been shown to play an important role in the demyelination process. Tissue plasminogen activator (tPA) is a serine protease that enhances the conversion of plasminogen into its active form plasmin, the principal tPA inhibitor...
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Fulcrum Therapeutics Announced Results of Phase 1 Clinical Trial of Losmapimod in FSHD CAMBRIDGE,...
Fulcrum Therapeutics Announced Results of Phase 1 Clinical Trial of Losmapimod in FSHDCAMBRIDGE, Mass., Oct. 04, 2019 (GLOBE NEWSWIRE) -- Fulcrum Therapeutics, Inc. (Nasdaq: FULC), a clinical-stage biopharmaceutical company focused on improving the lives of patients with genetically defined rare diseases, today announced...Drugs.com - Clinical TrialsFri Oct 04, 2019 07:10Athira Pharma Announces Completion of Phase 1b Clinical Trial of NDX-1017 in Alzheimer's PatientsSEATTLE, Oct. 2, 2019 -- Athira...
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Relationships between Metabolic Comorbidities and Occurrence, Severity, and Outcomes in Patients with Acute Pancreatitis: A Narrative ReviewBackground. The population of patients with acute pancreatitis treated by the staff at our department of gastroenterology includes those with mild and self-limited disease ranging to those with severe and fatal disease. Early diagnosis and accurate prediction of the severity and outcome of this disease, which is commonly seen by our department, is important for...
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Wnt Signaling Protects against Paclitaxel-Induced Spiral Ganglion Neuron Damage in the Mouse Cochlea In Vitro: It has been reported that paclitaxel administration could cause sensorineural hearing loss, and Wnt activation is important for the development and cell protection of mouse cochlea. However, the effect of Wnt signaling in spiral ganglion neurons (SGNs) damage induced by paclitaxel has not yet been elucidated. In this study, we explored the effect of paclitaxel on SGNs in the mouse cochlea...
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Incidence of Central Venous Catheter-Related Bloodstream Infections: Evaluation of Bundle Prevention
Incidence of Central Venous Catheter-Related Bloodstream Infections: Evaluation of Bundle Prevention in Two Intensive Care Units in Central Brazil: Background. Central venous catheter-associated bloodstream infections (CVC-BSIs) have been associated with increased length of hospital stay, mortality, and healthcare costs, especially in intensive care units (ICUs). The aim of this study was to evaluate the incidence density of CVC-BSIs before and after implementation of the bundle in a hospital of...
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PSYCHOLOGYsubmitted by /u/fkebld [link] [comments]Psychology03:38Detect and prevent fraudulent participants from ruining your research by employing these simple, actionable techniques backed up by science.submitted by /u/psychstudio [link] [comments]Psychology03:20Dealing with Death and Overcoming Grief - Harry Dallansubmitted by /u/hrayrdallakyan [link] [comments]PsychologySun Oct 06, 2019 23:04Following bilateral hippocampal lesions, patient have more frequent déja vus and prescience episodessubmitted...
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An Unusual Manifestation of Blastic Plasmacytoid Dendritic Cell Neoplasm as a Testicular Tumor: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a clinically aggressive hematologic malignancy arising from precursors of plasmacytoid dendritic cells that represent less than 1% of hematological malignancies. BPDCN initially presents with cutaneous involvement and a characteristic immunophenotype of CD4, CD56, and CD123 co-expression. Upon disease progression, BPDCN shows a strong predilection...
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Inflammation-Related Patterns in the Clinical Staging and Severity Assessment of Chronic Kidney Disease: Chronic kidney disease (CKD) is an irreversible loss of kidney function, and it represents a major global public health burden due to both its prevalence and its continuously increasing incidence. Mineral bone disorders (MBDs) constitute a hallmark of CKD, and alongside cardiovascular complications, they underlie a poor prognosis for these patients. Thus, our study focused on novel CKD biomarker...
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A Hospital-Based Study of Iodine Nutrition Status of Breastfeeding Mothers in Bangladesh: Adequacy of iodine nutrition status in breastfeeding mothers is vital in preventing iodine deficiency disorder (IDD) in neonates and children. The aim of the study was to assess urinary iodine status in breastfeeding mothers attending Bangabandhu Sheikh Mujib Medical University (BSMMU) hospital in Bangladesh. In this cross-sectional study carried out from January 2014 to January 2015, urinary iodine (UI; μgm/L)...
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PRO/AH/EDR> Undiagnosed disease - Sudan: (RS) human, cattle, RFIUndiagnosed -- SudanA man and more than 20 head of cattle died in Arbaat in Red Sea state on Thursday and Friday [3 & 4 Oct 2019] of an "unknown fever". So far, 3 people and 420 cows have died of the unknown disease that hit the area of Arbaat, north of Port Sudan, over the past weeks, medical doctor Ahmed Dereir told Radio Dabanga on Friday [4 Oct 2019].The symptoms of the disease are high fever among people, and bleeding and...
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Mild-to-Moderate Hearing Loss Leads to Lasting Changes in Central Auditory System Function: Hearing loss in early childhood is known to change how sounds are processed in the brain, but new research shows that even mild to moderate levels of deafness can result in these changes. (eLife. Oct. 1, 2019; http://bit.ly/2o2kaja.) Researchers at the MRC Cognition and Brain Sciences Unit at the University of Cambridge in the United Kingdom conducted a longitudinal study to examine late auditory evoked responses...
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Hoarding MisconceptionsWhat would it take for each of us to upset our wellness balance and become overwhelmed?Psychology Today Blogs08:26Forget Me Not: The Persistent Myth of Repressed MemoriesThe idea that people "block out" traumatic memories has been proven wrong over and over. Why, then, do therapists continue to promote it?Psychology Today Blogs06:21Cheating: the Effects of Anxious and Avoidant AttachmentAttachment theory suggests that dismissing people might cheat because they are running away...
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CXCR5+PD-1+ follicular helper CD8 T cells control B cell tolerance , Nature CommunicationsLatest additions to Europe PMCSun Oct 06, 2019 06:27The CXCL5/CXCR2 axis is sufficient to promote breast cancer colonization during bone metastasisNature CommunicationsLatest additions to Europe PMCSun Oct 06, 2019 06:27Effects of Model, Method of Collection, and Topography on Chemical Elements and Metals in the Aerosol of Tank-Style Electronic CigarettesScientific ReportsLatest additions to Europe PMCSun Oct...
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MedWorm Allergy & Immunology Clinical Trials , Allergy Antibiotics And Microbial ResistanceCondition: Infection Intervention: Procedure: penicillin allergy assessment pathway Sponsors: University of Leeds; University of Oxford Recruiting (Source: ClinicalTrials.gov)MedWorm Allergy & Immunology Clinical TrialsMon Sep 30, 2019 18:00Effects of Low Dose Ozone on Airway Inflammatory Responses in Adults With Asthma - Sedentary Nasal Ozone (Asthma SNOZ)Condition: Asthma, Allergic Interventions:...
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Histopathological Features of MRI‐Invisible Regions of Prostate Cancer LesionsBackground Previous studies have reported tumor volume underestimation with multiparametric (mp)MRI in prostate cancer diagnosis. Purpose To investigate why some parts of lesions are not visible on mpMRI by comparing their histopathology features to those of visible regions. Study Type Retrospective. Population Thirty‐four patients with biopsy‐proven prostate cancer scheduled for prostatectomy (median 68.7 years). Field...
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Coaching vs. Therapy – Referring Coaching Clients with Mental Illness: A recent article in the Wall Street Journal, titled "Executive Coach or Therapist? It's Getting Harder to Tell the Difference" (Bindley, 2019) again renews the debate about the blurred line between where coaching ends and where therapy begins.But why are personal issues coming up when coaches are hired by companies to do executive coaching (performance improvement or development)?Here's a good reason — According to a Hardvard...
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Antioxidants, Vol. 8, Pages 455: A Comprehensive Insight on the Health Benefits and Phytoconstituents of Camellia sinensis and Recent Approaches for Its Quality Control: Antioxidants, Vol. 8, Pages 455: A Comprehensive Insight on the Health Benefits and Phytoconstituents of Camellia sinensis and Recent Approaches for Its Quality ControlAntioxidants doi: 10.3390/antiox8100455Authors: Aboulwafa Youssef Gad Altyar Al-Azizi Ashour Tea, Camellia sinensis, which belongs to the...
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Children, Vol. 6, Pages 110: Gender-Related Challenges in Educational Interventions with Syrian Refugee Parents of Trauma-Affected Children in Turkey: Children, Vol. 6, Pages 110: Gender-Related Challenges in Educational Interventions with Syrian Refugee Parents of Trauma-Affected Children in TurkeyChildren doi: 10.3390/children6100110Authors: Melissa Diamond Charles Oberg Since 2012, more than three million Syrian refugees have fled to Turkey. While these refugees vary in socioeconomic...
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Pharmaceutical Researchers use REGEMAT 3D Technology for Drug Delivery: 3D bioprinting is becoming an interesting alternative for medical professionals and research institutions that choose a more personalized treatment for their patients, this has potential to improve the quality of life and reduce costs to health systems. One of the countries where these new technologies are emerging is Spain. For the last eight years, REGEMAT 3D, one of the pioneering companies in the region, has been looking...
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Sweden: Improving Writing Resolution in Electro-hydrodynamic 3D-Printing: In the recently published, 'Increasing the Writing Resolution for Electro-hydrodynamic 3D-Printing: by Active Steering of e-jet,' author Henrik Dan Bergman explores fabrication techniques in the microscopic realm for his thesis in Microsystems Technology at Sweden's Uppsala University.Electrohydrodynamic 3D-printing is a central focus, and especially due to its ability to print with thermoplastics. Historically, however, there...
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String of recalls implicate unknown volume of beef, veal products: For the second time officials are expanding a recall of beef and veal products, adding more than a dozen products, in a massive undertaking related to a government investigation into E. coli contamination.Initially Metro Ontario Inc. recalled a variety of products including ground beef, steaks and veal. But, the updates name "industry" as the recalling entity."Industry is recalling various raw beef and raw veal products from the marketplace...
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Tip Top Poultry is likely key to the mystery listeria outbreak in 13 states: That listeria-contaminated chicken from Tip Top Poultry is for certain responsible for multiple recalls in the United States and Canada.And while the U.S. Centers for Disease Control and Prevention (CDC) in Atlanta has not yet said so, that listeria-contaminated chicken is the likely source of an outbreak strain of Listeria monocytogenes the CDC has been investigating since before Aug. 23.As of that date, no source had...
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Use of Blood Lipid Indicators as a Screening Tool of Insulin Resistance among Individuals in Low-Income Country Sides of China: A Multiethnic Region Study: Objective. This study is aimed at evaluating the diagnostic value of blood lipid indicators (BLIs) for insulin resistance (IR) among major ethnic groups in Xinjiang, China, to identify the most valuable indicators and appropriate cut-off points for each ethnic group and to lay the foundation for the early detection, diagnosis, and treatment of...
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Mild-to-Moderate Hearing Loss Leads to Lasting Changes in Central Auditory System Function: Hearing loss in early childhood is known to change how sounds are processed in the brain, but new research shows that even mild to moderate levels of deafness can result in these changes. (eLife. Oct. 1, 2019; http://bit.ly/2o2kaja.) Researchers at the MRC Cognition and Brain Sciences Unit at the University of Cambridge in the United Kingdom conducted a longitudinal study to examine late auditory evoked responses...
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The emergence of non‐hypervascular hypointense nodules on enhanced MRI in patients with chronic hepatitis C: SummaryBackgroundIntrahepatic non‐hypervascular hypointense nodules (NHHNs) detected during the hepatobiliary phase of gadolinium‐ethoxybenzyl‐diethylenetriamine pentaacetic acid‐enhanced magnetic resonance imaging (EOB‐MRI) have the potential to transition into typical hypervascular hepatocellular carcinoma (HCC). However, the incidence and risk factors for the emergence of these nodules...
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Effects of myricetin‐3‐O‐α‐rhamnoside (myricitrin) treatment on urinary parameters of Wistar rats: AbstractObjectivesThis study aimed to investigate the diuretic efficacy of myricetin‐3‐O‐α‐rhamnoside (myricitrin), a common naturally occurring plant‐derived flavonoid, obtained from Marlierea eugeniopsoides (D.Legrand & Kausel) D.Legrand leaves in rats.MethodsFor that, female Wistar rats were treated by oral route with the different treatments and kept in metaboloic cages for 8‐h or 24‐h experiment....
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Vegan Hyaluronic Acid: a new skin care supplement hits the market: This week, RenewAlliance launched a beauty vitamin, vegan hyaluronic acid in capsule, form that promises to moisturize and plump skin from the inside out. Original enclosures:
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Dilemmas in the recognition of Sjogren syndrome [Letters]:
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Diffusion basis spectrum imaging for identifying pathologies in MS subtypes: AbstractDiffusion basis spectrum imaging (DBSI) combines discrete anisotropic diffusion tensors and the spectrum of isotropic diffusion tensors to model the underlying multiple sclerosis (MS) pathologies. We used clinical MS subtypes as a surrogate of underlying pathologies to assess DBSI as a biomarker of pathology in 55 individuals with MS. Restricted isotropic fraction (reflecting cellularity) and fiber fraction (representing...
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Cardiovascular disease in the literature: A selection of recent original research papersMyocardial perfusion imaging with regadenoson stress in advanced lung diseaseWhat is this image? 2019: Image 3 resultImpact of left bundle branch block on myocardial perfusion and metabolism: A positron emission tomography studyAbstractBackgroundBetter understanding of pathophysiological changes, induced by left bundle branch block (LBBB), may improve patient selection for cardiac resynchronization therapy (CRT)....
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Epigenetic silencing of microRNA-335 contributes to nasopharyngeal carcinoma metastasisAuthor links open overlay panelJu-hongYangaLie-KunLinaSongZhangbaCentral Laboratory, University of Chinese Academy of Science-Shenzhen Hospital, Song Bai Road 4253#, Shenzhen, Guang Dong TX 518106, PR ChinabDepartment of Otolaryngology, University of Chinese Academy of Science-Shenzhen Hospital, Song Bai Road 4253#, Shenzhen, Guang Dong TX 518106, PR ChinaReceived 25 June 2019, Available online 5 October 2019.Show...
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Complications of Palatal Pillar Implants: An analysis of the MAUDE database and literature reviewAuthor links open overlay panelRomanPovolotskiyMickey E.AbrahamAdam B.LeverantAmishavBreslerBorisPaskhoverDepartment of Otolaryngology – Head and Neck Surgery, Rutgers New Jersey Medical School, Newark, NJ, USAReceived 25 June 2019, Available online 5 October 2019.Show lesshttps://doi.org/10.1016/j.amjoto.2019.102303Get rights and contentAbstractPurposeThe Pillar Palatal Implant System is a minimally...
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Seltene Formen einer Insulinresistenz: Das Köbberling-SyndromLeitlinien für die Praxis 2019GasteditorialLebenslange Nachsorge nach bariatrischer ChirurgieZusammenfassungBaritrische Eingriffe werden in den letzten Jahren vermehrt durchgeführt, damit steigt auch die Anzahl der Patienten, die eine lebenslange, ernährungs-medizinische Nachsorge benötigen. Hierdurch soll präventiv einem Versorgungsmangel vorgebeugt werden. Spezialisierte Einrichtungen stoßen an die Grenzen ihrer Kapazität für eine solche...
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Issues with the Detection of Large Genomic Rearrangements in Molecular Diagnosis of 21-Hydroxylase DeficiencyAbstractMore than 95% of congenital adrenal hyperplasia (CAH) cases are associated with mutations in the 21-hydroxylase gene (CYP21A2) in the human leukocyte antigen (HLA) class III area on the short arm of chromosome 6p21.3. In the diagnosis of 21-hydroxylase deficiency, CYP21A2 genotyping is a valuable complement to biochemical investigations. Genotyping can confirm the diagnosis (or carrier...
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Glomerulonephritis and nephrotic syndrome in a child with DiGeorge syndrome: QuestionsAn infant with hyponatremia, hyperkalemia, and metabolic acidosis associated with urinary tract infection: QuestionsMild hypotonia and recurrent seizures in an 8-month-old boy: AnswersGlomerulonephritis and nephrotic syndrome in a child with DiGeorge syndrome: AnswersMild hypotonia and recurrent seizures in an 8-month-old boy: QuestionsAbstractHypomagnesemia with secondary hypocalcemia is a rare autosomal recessive...
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Naturopathic Oncology Care for Pediatric Cancers: A Practice SurveyAthanasios Psihogios, Jullie K. Ennis, and Dugald SeelySeptember 30, 2019Research ArticleUse of a Wearable EEG Headband as a Meditation Device for Women With Newly Diagnosed Breast Cancer: A Randomized Controlled TrialDenise M. Millstine, Anjali Bhagra, Sarah M. Jenkins, Ivana T. Croghan, Daniela L. Stan, Judy C. Boughey, Minh-Doan T. Nguyen, and Sandhya PruthiSeptember 30, 2019
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Usability of a spot test for isothiazolinones,Laura Tautvydaitė, Ulrik F. Friis, Jacob P. Thyssen, Jeanne D. JohansenVersion of Record online: 01 October 2019
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Contact DermatitisAccepted ArticlesAccepted, unedited articles published online and citable. The final edited and typeset Version of Record will appear in the future.ORIGINAL ARTICLESSkin application of glutathione and iron sulfate can inhibit elicitation of allergic contact dermatitis from hexavalent chromiumTina Lejding, Malin Engfeldt, Magnus Bruze, Marléne Isaksson, Cecilia Svedman, Erik Zimerson, Kaushal Verma, Martin MowitzFirst Published: 04 October 2019CONTACT POINTSIndependent contact allergy...
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Article Bites: To tube or not to tube in cardiac arrest?Investigators studied favorable neurological outcomes in cases where paramedics were randomized to use endotracheal intubation or supraglottic airways
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The "things themselves": challenging heuristics and inciting empathy via Husserlian phenomenologyAbstractI propose that the phenomenology of Edmund Husserl provides a meaningful mode of access to the patient experience. By reflecting on a real-life encounter with grief, my own medical training, and two works of literature, Nausea and Love in the Time of Cholera, I illustrate the application of philosophy and specifically phenomenology to clinical education. Phenomenology allows clinicians to strip...
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Comparison of the Physical Properties and in vivo Bioactivities of Flatwise-Spun Silk Mats and Cocoon-Derived Silk Mats for Guided Bone RegenerationAbstractThe main flaw of silkworm cocoon originated membranes for guided bone regeneration (GBR) techniques is that the maximum size of the membrane is determined by the size of the cocoon. Flatwise-spun silk does not have any limitation to its production size. The objective of this study was to compare flatwise-spun silk mats with cocoon-derived silk...
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29. Jahrestagung der Medizinischen Kontinenzgesellschaft ÖsterreichBeckenbodensenkungZusammenfassungDieser Artikel gibt einen kurzen Überblick über Beckenbodeninsuffizienz und Harninkontinenz, deren Abgrenzungen, Prävalenz und klinische Symptome. In der Folge wird die Diagnostik durch Anamnese und körperliche Untersuchung sowie weitere nichtinvasive und invasive Tests erläutert. Nun folgt die Therapie, hierbei werden verschiedene konservative und operative Therapiemöglichkeiten aufgeführt. Weiterhin...
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News-Screen UrologieEnzalutamid beim metastasierten hormon-sensitiven Prostatakarzinom (mHSPC)Blickdiagnose UrologieProstata: Anatomie und PhysiologieZusammenfassungDie Prostata ist eine besondere Drüse. Sie ist tief versteckt im kleinen Becken, umgeben von Fett, Bindegewebe, Beckenbodenmuskeln, Blutgefässen und Nerven. Sie wächst mit dem Alter, kann verschiedene Formen annehmen, die Harnblasenentleerung erheblich beeinträchtigen, chronisch oder akut entzündet sein oder zu unterschiedlich aggressiven...
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A rare case of pituitary oncocytoma successfully treated with single-fraction stereotactic Gamma Knife surgeryEfficacy of Dabrafenib for three children with brainstem BRAF V600E positive gangliogliomaAbstractPurposeChildren with unresectable brainstem-infiltrated ganglioglioma have poor progression-free survival when treated with conventional chemotherapy and radiation regimens. The BRAFV600E mutation occurs in a large number of gangliogliomas, making them amenable for targeted therapy using mutation-specific...
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The motivation behind the papers "Availability of life-cycle assessment studies in (different countries)"A Swedish comment on 'review: the availability of life-cycle studies in Sweden'Comparison of different tomato puree production phases from an environmental point of viewAbstractPurposeAgro-food systems are involved with considerable environmental impacts. Tomato as an important vegetable crop is processed into some products such as puree, ketchup, and paste. This study aimed to investigate the...
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Medical PrimatologyEarly ViewOnline Version of Record before inclusion in an issueORIGINAL ARTICLESBCL6 BTB‐specific inhibition via FX1 treatment reduces Tfh cells and reverses lymphoid follicle hyperplasia in Indian rhesus macaque (Macaca mulatta)Yanhui Cai, Meagan A. Watkins, Fengtian Xue, Yong Ai, Huiming Cheng, Cecily C. Midkiff, Xiaolei Wang, Xavier Alvarez, Adi Narayana Reddy Poli, Joseph M. Salvino, Ronald S. Veazey, Luis J. MontanerVersion of Record online: 01 October 2019SHORT PAPERSSIVcpz...
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DermatologyEarly ViewOnline Version of Record before inclusion in an issueLetter to the EditorsResearch LetterVitamin D deficiency in patients with acne vulgaris: A systematic review and meta‐analysisPrakash Acharya, Mahesh MathurVersion of Record online: 02 October 2019Brief ReportsRare indolent zygomycosis caused by subcutaneous Saksenaea vasiformis infectionMonton Tanabodee, Junjira Sawasdipong, Poonnawis Sudtikoonaseth, Vesarat WessagowitVersion of Record online: 02 October 2019Letters to the...
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Allergy & RhinologyEarly ViewOnline Version of Record before inclusion in an issueOriginal ArticlesCalmodulin and protein kinases A/G mediate ciliary beat response in the human nasal epitheliumBa Hung Do MD, Thi Nga Nguyen MD, Ryoko Baba PhD, Toyoaki Ohbuchi MD, PhD, Jun‐ichi Ohkubo MD, Takuro Kitamura MD, PhD, Tetsuro Wakasugi MD, Hiroyuki Morimoto DDS, PhD, Hideaki Suzuki MD, PhDVersion of Record online: 01 October 2019Original ArticlesEffects of modifying visual inhaler spacer usage instructions...
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Vector-Borne and Zoonotic Diseases , Table of Contents AlertVolume: 19, Number: 10 (October 2019)View this Issue OnlineOriginal ArticlesThe Dynamics of Ticks and Capybaras in a Residential Park Area in Southeastern Brazil: Implications for the Risk of Rickettsia rickettsii InfectionFernanda B. Passos Nunes, Silvio Carvalho da Silva, Alex Deiws Cieto, and Marcelo B. LabrunaVector-Borne and Zoonotic Diseases, Vol. 19, No. 10, October 2019: 711-716.Abstract | Full Text | PDF (166 KB) | PDF Plus (156...
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Exploring Spatiotemporal Associations of Borrelia burgdorferi (Spirochaetales: Spirochaetaceae), Babesia microti (Piroplasmida: Babesiidae), and Anaplasma phagocytophilum (Rickettsiales: Anaplasmataceae) Infection in Ixodes scapularis (Acari: Ixodidae)Eliza A.H. Little and Goudarz MolaeiVector-Borne and Zoonotic Diseases, Ahead of PrintAbstract | Full Text | PDF (299 KB) | PDF Plus (270 KB)Read More
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