! ORL via Alexandros G.Sfakianakis on Inoreader: Multicentre prospective clinical application of the T14 paediatric outcome tool.

! ORL via Alexandros G.Sfakianakis on Inoreader

Multicentre prospective clinical application of the T14 paediatric outcome tool. Aug 12th 2015, 10:43, by Hopkins C, Almeyda R, Alreefy H, Ismail-Koch H, Lim J, Possamai V, Powell S, Sharma R, Hore I Related Articles Multicentre prospective clinical application of the T14 paediatric outcome tool. J Laryngol Otol. 2015 Aug 11;:1-6 Authors: Hopkins C, Almeyda R, Alreefy H, Ismail-Koch H, Lim J, Possamai V, Powell S, Sharma R, Hore I Abstract OBJECTIVE: This study aimed to measure changes in disease-specific quality of life in children following tonsillectomy or adenotonsillectomy. METHODS: A multicentre prospective cohort study was performed involving seven ENT departments in England. A total of 276 children entered the study over a 2-month period: 107 underwent tonsillectomy and 128 adenotonsillectomy. Forty-one children referred with throat problems initially managed by watchful waiting were also recruited. The follow-up period was 12 months. Outcome measures were the T14, parental impressions of their child's quality of life and the number of days absent from school. RESULTS: One-year follow-up data were obtained from 150 patients (52 per cent). The mean baseline T14 score in the non-surgical group was significantly lower (T14 = 23) than in the tonsillectomy group (T14 = 31) or the adenotonsillectomy group (T14 = 35; p < 0.001). There was a significant improvement in the T14 scores of responders in all groups at follow up. The effect size was 1.3 standard deviations (SD) for the non-surgical group, 2.1 SD for the tonsillectomy group and 1.9 SD for the adenotonsillectomy group. Between-group differences did not reach statistical significance. A third of children in the non-surgical group underwent surgery during the follow-up period. CONCLUSION: Children who underwent surgical intervention achieved a significant improvement in disease-specific quality of life. Less severely affected children were managed conservatively and also improved over 12 months, but 1 in 3 crossed over to surgical intervention. PMID: 26259840 [PubMed - as supplied by publisher]

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