Allophony of /x029D;/ in Peninsular Spanish.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 5 δευτερόλεπτα
We report on an acoustic investigation of this consonant in Peninsular Spanish. Both preceding context and stress appear to be relevant factors. We also find an effect of style, with more constriction in more formal styles. The presence of a word boundary also affects the degree of constriction, although to a lesser extent. Although we […]
The protective effects of nebkhas on an oasis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 5 δευτερόλεπτα
Publication date: March 2016 Source:Aeolian Research, Volume 20 Author(s): Xueyong Zou, Jifeng Li, Bo Liu, Chunlai Zhang, Hong Cheng, Xiaoxu Wu, Liqiang Kang, Ruxing Wang Oases are of great importance to the sustainable development of economies and societies in desert regions. Thus, it is important to understand how many oases have survived for hundreds and […]
Endothelial protein kinase MAP4K4 promotes vascular inflammation and atherosclerosis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 5 δευτερόλεπτα
Article Atherosclerosis is an inflammatory disease with limited therapeutic options. Here, the authors show that protein kinase MAP4K4 regulates vascular inflammation underlying atherosclerotic plaque development and that its inhibition prevents the disease and promotes lesion regression in mice, proposing a new atherosclerosis treatment. Nature Communications doi: 10.1038/ncomms9995 Authors: Rachel J. Roth Flach, Athanasia Skoura, Anouch […]
Exclusive photorelease of signalling lipids at the plasma membrane
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 5 δευτερόλεπτα
Article Caged signalling intermediates are powerful cell biological tools, however it can be challenging to precisely control where activation occurs. Nadler et al . develop a caging group that specifically targets the plasma membrane, and demonstrate spatially controlled activation of arachidonic acid signalling. Nature Communications doi: 10.1038/ncomms10056 Authors: André Nadler, Dmytro A. Yushchenko, Rainer Müller, […]
A genome-wide association study identifies four novel susceptibility loci underlying inguinal hernia
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 5 δευτερόλεπτα
Article Inguinal hernia has high lifetime prevalence, especially in men. This genome-wide association study identifies 4 loci to be associated with inguinal hernia, and shows expression of nearby genes in mouse connective tissues. Nature Communications doi: 10.1038/ncomms10130 Authors: Eric Jorgenson, Nadja Makki, Ling Shen, David C. Chen, Chao Tian, Walter L. Eckalbar, David Hinds, Nadav […]
Defining the impact of the use of granulocyte colony stimulating factors on the incidence of chemotherapy-induced neutropenia in patients with gynecologic malignancies
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 5 δευτερόλεπτα
Purpose The objectives of this study were to characterize the incidence of chemotherapy-induced neutropenia (CIN) and febrile neutropenia (FN) with specific chemotherapy agents commonly used in the treatment of gynecologic malignancies, as well as defining the impact of granulocyte colony stimulating factors (G-CSF) on the prevention of CIN and FN in this patient population. Methods […]
Why adjuvant chemotherapy for stage III colon cancer was not given: Reasons for non-recommendation by clinicians or patient refusal
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 5 δευτερόλεπτα
Aim The aim of our study was to evaluate stage III colon cancer patients discussed at a multidisciplinary team meeting to identify reasons for clinicians not recommending adjuvant chemotherapy and reasons for patients declining recommended chemotherapy. Methods A retrospective, single institution Australian study was conducted on all surgically managed stage III colon cancer patients diagnosed […]
MM-398 (nanoliposomal irinotecan): emergence of a novel therapy for the treatment of advanced pancreatic cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 5 δευτερόλεπτα
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YxKdDU via IFTTT
Corrigendum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 5 δευτερόλεπτα
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YxKffc via IFTTT
Corrigendum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 5 δευτερόλεπτα
Future Oncology January 2016, Vol. 12, No. 2, Pages 272-272. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22mjGyh via IFTTT
Fibrosarcomatous dermatofibrosarcoma metastasizing to ..
Fibrosarcomatous dermatofibrosarcoma metastasizing to retroperitoneum four years after resection of primary lesion - A case report with review of literature: AbstractDermatofibrosarcoma protuberans (DFSP) is a rare soft tissue neoplasm arising from mesenchymal cells, making up about 6% of all soft tissue tumours1. The most commonly involved sites are the trunk (42–72%) and proximal extremities (16–30%)2. It generally has intermediate- to low-grade malignancy potential with the exception of the fibrosarcomatous variant (high-grade). This variant is more likely to metastasise (in les... περισσότερα »
Primary mantle cell lymphoma of the tonsil
Primary mantle cell lymphoma of the tonsil: An uncommon case: AbstractNon-Hodgkin lymphoma of the Waldeyer’s ring is a relatively rare entity and the palatine tonsil is the most frequently involved site. Although the exact aetiology remains unclear, a number of predisposing factors have been identified including human immunodeficiency virus and Epstein-Barr infection. An 82-year-old male patient presented with a sensation of fullness of the throat. Physical examination revealed a smooth non-tender mass in the right palatine tonsil measuring approximately 3.5 x 3cm. Serology was neg... περισσότερα »
A metallic pin
Appendicular perforation caused by metallic pin–An unusual presentation: AbstractAppendicitis caused by a foreign body is quite rare. Such a case becomes even more peculiar when ingestion of foreign body cannot be recalled or there has been no symptom prior to presentation as appendicular perforation. We report the case of a 20-year-old female, who presented with symptoms of appendicitis of one day duration in whom a metallic pin was discovered during surgery.
Silver-impregnated dressing with povidone iodine based-dressing
Comparison of results of silver-impregnated dressing with povidone iodine based-dressing in patients with diabetic foot: Abstract Aim-BackgroundThe use of silver in the management of burn wounds is well known. This prospective study was undertaken to evaluate the efficacy of silver-impregnated dressing in patients with diabetic foot. Materials and methodsThis study was conducted in the Department of Surgery at a tertiary care hospital in North India. It was a randomized case control study to compare the effectiveness of silver-impregnated dressings with conventional povidone io... περισσότερα »
Glycoproteomic studies of IgE from a novel hyper IgE syndrome linked to PGM3 mutation
Glycoproteomic studies of IgE from a novel hyper IgE syndrome linked to PGM3 mutation: AbstractGlycans serve as important regulators of antibody activities and half-lives. IgE is the most heavily glycosylated antibody, but in comparison to other antibodies little is known about its glycan structure function relationships. We therefore describe the site specific IgE glycosylation from a patient with a novel hyper IgE syndrome linked to mutations in PGM3, which is an enzyme involved in synthesizing UDP-GlcNAc, a sugar donor widely required for glycosylation. A two-step method was de... περισσότερα »
Variations on a Theme: Mild Hearing Loss and Word Recognition Scores
Variations on a Theme: Mild Hearing Loss and Word Recognition Scores Timmer et al (2015) report that the prevalence rate of mild hearing impairment varies greatly with the definition. They report that the weak correlations between audiologic assessments and patient-based self-reported difficulties indicate further assessment of individuals with mild hearing impairment is warranted. In their Table 2 (page 788) they offer a “summary of descriptive classifications of mild hearing impairment” which includes similar, although different, common definitions of mild hearing loss. Organ... περισσότερα »
Single-Sided Deafness, Cochlear Implants, and Speech Understanding
Single-Sided Deafness, Cochlear Implants, and Speech Understanding: Zeitler et al (2015) reported on nine people (ages 12 to 63 years) with single-sided deafness (SSD) and normal hearing in the other ear, all of whom underwent cochlear implantation in the SSD ear. With regard to post-op speech understanding in noise, the authors report “one of our aims was to assess the value of a CI for SSD patients when the listening environment simulated a ‘real world’ situation, that is, listening in a restaurant where the talker was on the side of the CI. Single-Sided Deafness, Cochlear Impl... περισσότερα »
Zinc Modulates Nanosilver-Induced Toxicity in Primary Neuronal Cultures
Zinc Modulates Nanosilver-Induced Toxicity in Primary Neuronal Cultures: AbstractSilver nanoparticles (NAg) have recently become one of the most commonly used nanomaterials. Since the ability of nanosilver to enter the brain has been confirmed, there has been a need to investigate mechanisms of its neurotoxicity. We previously showed that primary neuronal cultures treated with nanosilver undergo destabilization of calcium homeostasis via a mechanism involving glutamatergic NMDA receptors. Considering the fact that zinc interacts with these receptors, the aim of the present study was... περισσότερα »
Methylglyoxal Causes Cell Death in Neural Progenitor Cells and Impairs Adult Hippocampal Neurogenesis
Methylglyoxal Causes Cell Death in Neural Progenitor Cells and Impairs Adult Hippocampal Neurogenesis: AbstractMethylglyoxal (MG) is formed during normal metabolism by processes like glycolysis, lipid peroxidation, and threonine catabolism, and its accumulation is associated with various degenerative diseases, such as diabetes and arterial atherogenesis. Furthermore, MG has also been reported to have toxic effects on hippocampal neurons. However, these effects have not been studied in the context of neurogenesis. Here, we report that MG adversely affects hippocampal neurogenesis an... περισσότερα »
Simultaneous cochlear implantation and labyrinthectomy for advanced Ménière's disease
Clinical RecordSimultaneous cochlear implantation and labyrinthectomy for advanced Ménière's diseaseR L Heywooda1a2 c1 and M D Atlasa1a2 a1 Sir Charles Gairdner Hospital, Perth, Australia a2 Ear Science Institute Australia, Perth, Australia Abstract Background: Patients with Ménière's disease can develop unaidable sensorineural hearing loss. Cochlear implantation has recently been utilised in this group with favourable results. A more challenging group are those with intractable vertigo, and they have traditionally posed a significant management dilemma. Case report: Two female patient...περισσότερα »
Alterations of mucosa of the larynx and hypopharynx in patients with mucopolysaccharidoses
Main ArticleAlterations of mucosa of the larynx and hypopharynx in patients with mucopolysaccharidosesA Keilmanna1 c1, F Bendela2, S Nospesa2, C Lampea3 and A K Läßiga2 a1 Voice Care Center, Bad Rappenau, Germany a2 Division of Communication Disorders, Department of ORL, University Medical Center, Mainz, Germany a3 Center for Rare Diseases, Department of Child and Adolescent Medicine, Horst Schmidt Klinik, Wiesbaden, Germany Abstract Objective: This study aimed to: assess the mucosal alterations of the larynx and hypopharynx typical for mucopolysaccharidoses, in a standardised manner;... περισσότερα »
Children with symptoms of sleep-disordered breathing
Main ArticleHealthcare provider contact for children with symptoms of sleep-disordered breathing: a population surveyG Gudnadottira1, A Ehnhagea2 a3, M Bendea4, M Anderssona5, A Cervina7, L O Cardella6and J Hellgrena1 c1 a1 Department of Otorhinolaryngology, Institution for Clinical Sciences, Sahlgrenska Academy at Gothenburg University, Sahlgrenska University Hospital, Gothenburg, Sweden a2 Department of Clinical Sciences, Intervention and Technology, Division Otorhinolaryngology, Karolinska Institutet, Sweden a3 Nacka Närsjukhus Proxima, Stockholm, Sweden a4 Department of Otorhinolary... περισσότερα »
The management of chronic otitis media
Main ArticleDemographic factors associated with loss to follow up in the management of chronic otitis media: case–control studyR Nasha1 c1, R Foxa1, R Srinivasana1, A Majithiaa1 and A Singha1 a1 Department of Otolaryngology, Head and Neck Surgery, Northwick Park Hospital, Harrow, UK Abstract Objective: The likelihood of a patient attending regular follow up can affect decision making when planning and performing tympanomastoid surgery. This study investigated whether demographic factors were associated with loss to follow up. Methods: A database of patients who had been investigated a...περισσότερα »
Microbial causes of complicated acute bacterial rhinosinusitis
Main ArticleMicrobial causes of complicated acute bacterial rhinosinusitis and implications for empirical antimicrobial therapyM S Miaha1, P Nixa1 c1, A Koukkoullisa1 and J Sandoea2 a1 Department of Otorhinolaryngology – Head and Neck Surgery, Leeds General Infirmary, UK a2 Department of Microbiology, Leeds General Infirmary, UK Abstract Objectives: Very little up-to-date information is available on the microbiology of complicated acute bacterial rhinosinusitis. Reliable microbiology testing is necessary to inform current empirical antimicrobial treatments. This study was conducted in...περισσότερα »
Post-thyroidectomy haematoma
Main ArticleRisk factors for post-thyroidectomy haematomaM Pereraa1 c1, L Anabella1, D Pagea1, T Hardinga1, N Gnaneswarana1 and S Chana1a2 a1 Department of Surgery, Western Health, Footscray, Australia a2 Academic Surgery, University of Melbourne, Victoria, Australia Abstract Background: There has been increasing emphasis on performing ‘same-day’ or ‘out-patient’ thyroidectomy to reduce associated costs. However, acceptance has been limited by the risk of potentially life-threatening post-operative bleeding. This study aimed to review current rates of post-operative bleeding in a metro... περισσότερα »
Children with chronic suppurative otitis media before and after dry mopping with tissue spears
Main ArticleDo tissue spears used to clear ear canal pus improve hearing? A case series study of hearing in remote Australian Aboriginal children with chronic suppurative otitis media before and after dry mopping with tissue spearsK Sparrowa1 c1, L Sancheza1, D Turnera2, P MacFarlanea3a4 and A S Carneya3a4 a1 Speech Pathology and Audiology, School of Health Sciences, Flinders University, Adelaide, Australia a2 Haematology and Genetic Pathology, School of Medicine, Flinders University, Adelaide, Australia a3 Department of Surgery, School of Medicine, Flinders University, Adelaide, Aus... περισσότερα »
Air pollutants aggravates atopic dermatitis (AD)
Airborne formaldehyde causes skin barrier dysfunction in atopic dermatitis: Summary Background It remains to be elucidated whether exposure to air pollutants aggravates atopic dermatitis (AD). Objective This study aimed to evaluate the effect of exposure to formaldehyde for 1 hour and 2 hours on skin barrier function in both the control and the AD groups. Methods In 41 patients with AD and 34 healthy children, a provocation test was performed in which two different areas of normal-appearing skin on the forearm were stimulated with airborne formaldehyde at 500 μg/m3 or placebo for 2 ...περισσότερα »
Molluscum Contagiosum Viral Infection Treated With a Dilute Povidone-Iodine/Dimethylsulfoxide Preparation
Molluscum Contagiosum Viral Infection Treated With a Dilute Povidone-Iodine/Dimethylsulfoxide Preparation: Abstract IntroductionMolluscum contagiosum is a viral infection of the skin that is spread from direct contact, either via person to person by touching affected lesions or innocuously via fomites. The condition is often socially stigmatizing, motivating patients to seek treatment. There are many anecdotal remedies, but none have been overwhelmingly effective in controlled clinical trials. Case ReportA 16-year-old girl presented with approximately 75 lesions on her inner t... περισσότερα »
Increased risk of trigeminal neuralgia in patients with migraine
Increased risk of trigeminal neuralgia in patients with migraine: A nationwide population-based study: Objectives The objectives of this article are to evaluate the association between migraine and trigeminal neuralgia and to investigate the effects of age, sex, migraine subtype, and comorbid risk factors on trigeminal neuralgia development. Methods This population-based cohort study was conducted using data from Taiwan’s National Health Insurance Research Database. Individuals aged ≥ 20 years with neurologist-diagnosed migraine between 2005 and 2009 were included. A non-headache ...περισσότερα »
Breach of the thyroid capsule and lymph node capsule in node-positive papillary and medullary thyroid cancer
European Journal of Surgical Oncology (EJSO) Volume 41, Issue 6, June 2015, Pages 766–772 Breach of the thyroid capsule and lymph node capsule in node-positive papillary and medullary thyroid cancer: Different biology - A. Machens, , - H. Dralle - Department of General, Visceral and Vascular Surgery, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, Halle (Saale) D-06097, Germany Abstract Aims The higher incidence of extranodal growth (breach of a lymph node capsule) in the presence of extrathyroidal extension (breach of the thyroid capsule) ... περισσότερα »
Curative Surgical Resection for Esophageal Squamous Cell Cancer Associated with Multiple Primary Cancers
Safety and Benefit of via European Journal of Surgical Oncology (EJSO) Publication date: Available online 10 December 2015 *Source:*European Journal of Surgical Oncology (EJSO) Author(s): Y. Otowa, T. Nakamura, G. Takiguchi, M. Yamamoto, S. Kanaji, T. Imanishi, T. Oshikiri, S. Suzuki, K. Tanaka, Y. Kakeji BackgroundRecent enhancements in surgical techniques have led to improved outcomes for esophageal cancer. Recent findings have showed that esophageal cancer is frequently associated with multiple primary cancers, and surgical resection is usually complicated in such cases. The aim of ... περισσότερα »
Posterior decompression and spine stabilization for metastatic spinal cord compression in the cervical spine
. A matched pair analysis via European Journal of Surgical Oncology (EJSO) Publication date: December 2015 *Source:*European Journal of Surgical Oncology (EJSO), Volume 41, Issue 12 Author(s): M. Lei, Y. Liu, L. Yan, C. Tang, S. Liu, S. Zhou PurposeThis study aims to compare clinical outcome of cervical spine metastasis with those of thoracic and lumbar spine metastasis after surgery for metastatic spinal cord compression (MSCC).Patients and methodsData from nineteen patients with cervical spine metastasis were matched to thirty-eight patients with thoracic spine metastasis and thirty-e... περισσότερα »
Tumour Angiogenesis
Tumour Angiogenesis: AbstractIt has been over 40 years since Judah Folkman published his classic article in the New England Journal of Medicine, entitled “Tumor angiogenesis: therapeutic implications” (N Engl J Med 285:1182–1186, 1971). At the time Folkman proposed three bold postulates: (i) angiogenesis is essential for tumour growth beyond minimal size; (ii) tumours secrete a “tumor angiogenesis factor” that is responsible for inducing angiogenesis; and (iii) anti-angiogenesis is a potential cancer therapeutic strategy. After many years of controversy and scientific research prog... περισσότερα »
Risk of thyroid cancer among patients with familial adenomatous polyposis
Risk of thyroid cancer among Caribbean Hispanic patients with familial adenomatous polyposis: AbstractFamilial adenomatous polyposis (FAP) is an inherited form of colorectal cancer characterized by hundreds of adenomatous polyps in the colon and rectum. FAP is also associated with thyroid cancer (TC), but the lifetime risk is still unclear. This study reports the standardized incidence ratio (SIR) of TC in Hispanic FAP patients. TC incidence rates in patients with FAP between the periods of January 1, 2006 to December 31, 2013 were compared with the general population through direc...περισσότερα »
OnabotulinumtoxinA versus oral migraine prophylactic medications on headache-related resource utilization in the management of chronic migraine
Comparative effectiveness of onabotulinumtoxinA versus oral migraine prophylactic medications on headache-related resource utilization in the management of chronic migraine: Retrospective analysis of a US-based insurance claims database: Background Migraine, especially chronic migraine (CM), causes substantial disability; however, health care utilization has not been well characterized among patients receiving different migraine prophylactic treatments. Methods Using a large, US-based, health care claims database, headache-related health care utilization was evaluated among adults ... περισσότερα »
Sodium azide ingestion and secondary contamination risk in healthcare workers
This study reports the follow-up of healthcare staff directly involved in managing a fatal sodium azide ingestion. Clinical staff directly involved with the case were contacted by telephone or in person. Data collected were age, sex, time in contact with the patient, time off work following the incident and whether or not this was because of physical complications of exposure. Ten individuals had close contact with the case. Of these, five were men, median age was 39 years (range 22–52); four described being in close contact for greater than 60 min, three for 15–60 min and three for ... περισσότερα »
Bedside lung ultrasound for monitoring the effectiveness of prehospital treatment with continuous positive airway pressure in acute decompensated heart failure
[image: image]Objective: The aim of this pilot study was to determine the usefulness of prehospital lung ultrasound in monitoring the effectiveness of treatment with continuous positive airway pressure (CPAP) versus standard therapy in patients with acute decompensated heart failure (ADHF). Materials and methods: Twenty patients with ADHF were enrolled in this prospective, observational study. They were allocated randomly to a CPAP group (CPAP and standard therapy) or a control group (standard therapy only). Lung ultrasound was performed in each group and B-lines were counted and co...περισσότερα »
Renal colic: current protocols for emergency presentations
Flank pain caused by renal colic is a common presentation to emergency departments. This paper reviews the acute clinical assessment of these patients, outlines appropriate diagnostic strategies with labwork and imaging and updates the reader on conservative treatments, suitable choices for analgesia and indications for surgical intervention. Prompt diagnosis and appropriate treatment instituted in the Emergency Department can rapidly and effectively manage this excruciatingly painful condition. from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OHtoRR via IFTTT
Clinical interventions by helicopter emergency medical service teams: Time for key performance indicators?
No abstract available from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QDhxdM via IFTTT
Sharps and high-pressure injection injuries in veterinary and animal workers
[image: image]Needlestick and 'sharps' injuries among those working with animals are a significant, under-reported and often ill-understood problem. Many patients present initially to Emergency Departments, where their potential to cause local and systemic infections and injury, zoonoses, allergic or anaphylactic reactions and death may be unrecognized. Increased awareness of the possibility of adverse effects and the consequences of these specific injuries is essential. from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OHtoRM via IFTTT
The diagnostic accuracy of the HITSNS prehospital triage rule for identifying patients with significant traumatic brain injury: a cohort study
[image: image]Diversion of suspected traumatic brain injury (TBI) patients to trauma centres may improve outcomes by expediting access to specialist neurosurgical care. This study aimed to determine the accuracy of the Head Injury Straight to Neurosurgery (HITSNS) triage rule for identifying patients with significant TBI. A diagnostic cohort study was performed using data from the HITSNS trial, the Trauma Audit and Research Network registry and the North East Ambulance service database. Sensitivity and specificity of the HITSNS triage rule were calculated against a reference standar... περισσότερα »
Fascia iliaca compartment block for hip fractures: experience of integrating a new protocol across two hospital sites
[image: image]Objective: Fascia iliaca compartment block (FICB) administered through the loss of resistance technique effectively reduces pain and opiate requirement in elderly patients with hip fractures. FICB is a simple technique and is easily taught. This paper plots the implementation of FICB in two hospitals. Methods: A continuous audit process of two separate sites recorded the uptake of the FICB on an organizational level. An additional control group (CG) of 100 patients were analysed to compare pain scores (using the Numerical Rating Scale) and opiate requirements between g...περισσότερα »
Traumatic cardiac arrest: central venous cannulation under direct vision following rescue thoracotomy
No abstract available from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OHtlW1 via IFTTT
Urgent carotid duplex and head computed tomography versus ABCD2 score for risk stratification of patients with transient ischemic attack
[image: image]Objectives: The aim of the study was to prospectively compare the prognostic value of ABCD2 score, urgent carotid ultrasound (CUS), and unenhanced head computed tomography (UHCT) in patients presenting to the emergency department with transient ischemic attack (TIA). Patients and methods: We carried out a prospective observational study including consecutive adult patients with TIA. Each patient underwent ABCD2 score assessment, urgent CUS, and UHCT within 24 h from presentation. The primary outcome was the occurrence of ischemic stroke within 30 days. Results: We incl... περισσότερα »
Emergency medicine: this is what we do
No abstract available from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QDhvT9 via IFTTT
Agreement between ambulance and hospital records for information promoting urgent stroke treatment decisions
[image: image]Objective: Rapid decision-making during acute stroke care can improve outcomes. We wished to assess whether crucial information to facilitate decisions is routinely collected by emergency practitioners before hospital admission. Materials and methods: We examined whether ambulance records contained information relevant to a thrombolysis treatment decision for consecutive stroke admissions to three emergency departments in England between 14 May 2012 and 10 June 2013. Results: In all, 424 of 544 (78%) records included a paramedic diagnosis of stroke. Twice as many hospi... περισσότερα »
Theoretical knowledge and skill retention 4 months after a European Paediatric Life Support course
[image: image]Objective: The European Paediatric Life Support (EPLS) provider course aims at training doctors and nurses in the efficient and prompt management of cardiopulmonary arrest in children. EPLS is a 2-day European Resuscitation Council course, involving the teaching of theoretical knowledge and practical skills. The aim of the study was to evaluate the retention of theoretical knowledge and certain skills of EPLS providers 4 months after the course. Materials and methods: In total, 80 doctors and nurses who attended three EPLS provider courses, from May 2012 to December 20... περισσότερα »
Analysis of a data-fusion system for continuous vital sign monitoring in an emergency department
[image: image]Objective: The aim of the study was to evaluate the ability of a data-fusion patient status index (PSI) to detect patient deterioration in the emergency department (ED) in comparison with track-and-trigger (T&T). Materials and methods: A single-centre observational cohort study was conducted in a medium-sized teaching hospital ED. Vital sign data and any documented T&T scores (paper T&T) were collected from adults attending the resuscitation room, majors or observation ward. For each set of vital signs, we retrospectively calculated T&T (eT&T). PSI was calculated retro... περισσότερα »
A second opinion?
Is there evidence for a better health care for cancer patients after a second opinion? A systematic review: Abstract BackgroundWith growing complexity of diagnostics and therapy, as well as increasing involvement of patients in the decision-making process, there is more and more demand for second opinions in oncology. This literature review aims at analyzing the benefits and risks involved, as well as the tools needed to establish a structured program for second opinion within a modern healthcare system. MethodsA systematic literature search was performed using MEDLINE and Emb...περισσότερα »
Targeting STAT3/miR-21 axis inhibits epithelial-mesenchymal transition via regulating CDK5 in head and neck squamous cell carcinoma
Targeting STAT3/miR-21 axis inhibits epithelial-mesenchymal transition via regulating CDK5 in head and neck squamous cell carcinoma: Abstract BackgroundAbnormal activation of STAT3 and miR-21 plays a vital role in progression and invasion of solid tumors. The cyclin-dependent kinase 5 (CDK5) is reported to contribute to cancer metastasis by regulating epithelial-mesenchymal transition (EMT). However, the role of STAT3/miR-21 axis and CDK5 in head and neck squamous cell carcinoma remains unclear. MethodsWe measured the expression of miR-21, CDK5 and EMT markers in 60 HNSCC tumor... περισσότερα »
The internal acoustic canal - another review area in paediatric sensorineural hearing loss
The internal acoustic canal - another review area in paediatric sensorineural hearing loss: AbstractMorphological abnormalities of the internal acoustic canal (IAC), albeit rare, are sometimes associated with hearing loss in children. We present an illustration of the spectrum of IAC abnormalities together with a brief review of the embryology and anatomy of the IAC and the techniques used when imaging the petrous temporal bone. This review focuses on morphological abnormalities of the IAC together with their clinical implications and impact on clinical management.
Preoperative radiotherapy for extremity soft tissue sarcoma
Preoperative radiotherapy for extremity soft tissue sarcoma; past, present and future perspectives on dose fractionation regimens and combined modality strategies: [image: gr1.sml] Introduction: This critical review aims to summarize published data on limb sparing surgery for extremity soft tissue sarcoma in combination with pre-operative radiotherapy (RT). Methods: This review is based on peer-reviewed publications using a PubMed search on the MeSH headings “soft tissue sarcoma” AND “preoperative radiotherapy”. Titles and abstracts screened for data including “fraction size AN... περισσότερα »
Skin Cancer: the Role of Gender and Linguistic Acculturation
A Qualitative Exploration of Latinos’ Perceptions About Skin Cancer: the Role of Gender and Linguistic Acculturation: AbstractLatinos have the highest rate of skin cancers among U.S. minorities. Despite a rising incidence of melanoma—the deadliest form of skin cancer—and greater disease burden, Latinos tend to have poor awareness of skin cancer risk factors which may inhibit preventive action. We expanded on prior work by qualitatively examining potential moderators (i.e., gender, acculturation) of skin cancer perceptions among Latinos from El Barrio in Harlem, New York City. Four ... περισσότερα »
Consensus on management of advanced medullary thyroid carcinoma
Consensus on management of advanced medullary thyroid carcinoma on behalf of the Working Group of Thyroid Cancer of the Spanish Society of Endocrinology (SEEN) and the Spanish Task Force Group for Orphan and Infrequent Tumors (GETHI): Abstract BackgroundOf all thyroid cancers, <5 % are medullary (MTC). It is a well-characterized neuroendocrine tumor arising from calcitonin-secreting C cells, and *RET* gene plays a central role on its pathogeny. MethodsThe electronic search was conducted using MEDLINE (PubMed), EMBASE and Cochrane Central Register of Controlled Trials. Quality a... περισσότερα »
Chronic rhinosinusitis and the incidence of asthma
A population-based study investigating chronic rhinosinusitis and the incidence of asthma: Objectives/Hypothesis Chronic rhinosinusitis (CRS) is an inflammatory disease of the paranasal sinuses, associated with reduced health-related quality of life and increased utilization of healthcare services. Chronic upper and lower respiratory diseases often coexist, although the extent to which CRS is associated with developing asthma remains unclear. To investigate the effect of CRS on receiving a subsequent diagnosis of asthma, we used data from a previously conducted national, longitudin... περισσότερα »
Static endoscopic evaluation of swallowing: Transoral endoscopy during clinical swallow evaluations
Static endoscopic evaluation of swallowing: Transoral endoscopy during clinical swallow evaluations: Objectives/Hypothesis To determine the sensitivity and specificity for assessing pharyngeal residue, laryngeal penetration, and tracheal aspiration when comparing findings from the Static Endoscopic Evaluation of Swallowing (SEES) with findings from the Videofluoroscopic Swallow Study (VFSS). Methods Retrospective study at a tertiary academic medical center. Records were reviewed consecutive outpatients who underwent both SEES and VFSS evaluations. Video segments from SEES and VFSS e... περισσότερα »
Correlation between remnant inferior turbinate volume and symptom severity of empty nose syndrome
Correlation between remnant inferior turbinate volume and symptom severity of empty nose syndrome: Objectives/Hypothesis Empty nose syndrome (ENS) is an iatrogenic disorder caused by turbinate reduction procedures, which results in considerable nasal dysfunction and severely impaired quality of life. However, there is a lack of data that explains the relationship between the degree of turbinate reduction and subjective symptoms. The aim of this study was to evaluate the effects of remnant inferior turbinate volume on symptom severity. Study Design We retrospectively analyzed data fr... περισσότερα »
Upper neck papillary thyroid cancer.Thyroglossal duct cyst-associated papillary thyroid cancer, pyramidal lobe papillary thyroid cancer, and Delphian node papillary thyroid cancer metastasis
Upper neck papillary thyroid cancer: A new proposed term for the composite of Thyroglossal duct cyst-associated papillary thyroid cancer, pyramidal lobe papillary thyroid cancer, and Delphian node papillary thyroid cancer metastasis: Objectives/Hypothesis Thyroglossal duct cyst (TGDC) is a common congenital anomaly, but TGDC carcinoma is rare. Thyroglossal duct cyst carcinoma management is controversial, especially that of the orthotopic thyroid gland. We aim to provide an insight into the pathologic basis of this management controversy through the review of 28 TGDC cancer cases, t... περισσότερα »
Dysphagia and malignancy
Dysphagia and malignancy: A three-year follow-up and survey of National Cancer Registry data: Objectives/Hypothesis Dysphagia may cause concern about malignancy. Symptoms are often unspecific; thus, it is essential to identify those requiring further investigations. Study Design Retrospective study combined with patient survey. Methods Case records of the 303 dysphagia patients referred in 2009 to Helsinki University Hospital, Department of Otorhinolaryngology–Head and Neck Surgery were surveyed. Based on clinical data, the main cause of symptoms divided patients into five groups. A...περισσότερα »
Voice problems and depression among adults
Voice problems and depression among adults in the United States: Objectives/Hypothesis Prior studies have observed a high prevalence of psychosocial distress, including depression, in patients with voice problems. However, these studies have largely been performed in care-seeking patients identified in tertiary care voice clinics. The objective of this study was to examine the association between depression and voice problems in the U.S. population. Study Design Cross-sectional analysis of National Health Interview Survey (NHIS) data. Methods We identified adult cases reporting a voic... περισσότερα »
Transnasal endoscopic medial maxillary sinus wall transposition with preservation of structures
Transnasal endoscopic medial maxillary sinus wall transposition with preservation of structures: Objectives/Hypothesis To evaluate the increase in access to the maxillary sinus (MS) with transnasal endoscopic medial maxillary sinus wall transposition (TEMMT), while preserving major structures of the nasal cavity. Study Design The study was divided into three parts: anatomical, radiographic, and case series. Methods Three cadaveric dissections (total of six sides) confirmed the feasibility of the TEMMT approach. Radiographic measurements using maxillofacial computed tomography scans ...περισσότερα »
Dynamics of phonatory posturing at phonation onset
Dynamics of phonatory posturing at phonation onset: Introduction In speech and singing, the intrinsic laryngeal muscles set the prephonatory posture prior to the onset of phonation. The timing and shape of the prephonatory glottal posture can directly affect the resulting phonation type. We investigated the dynamics of human laryngeal phonatory posturing. Methods Onset of vocal fold adduction to phonation was observed in 27 normal subjects using high-speed video recording. Subjects were asked to utter a variety of phonation types (modal, breathy, pressed, /i/ following sniff). Digit... περισσότερα »
Effects of peritumoral nanoconjugated cisplatin on laryngeal cancer stem cells
Effects of peritumoral nanoconjugated cisplatin on laryngeal cancer stem cells: Objectives/Hypothesis To evaluate the efficacy of peritumoral hyaluronic acid (HA)-cisplatin therapy in a murine model of laryngeal squamous cell carcinoma and to evaluate its effect on cancer stem cells (CSCs). Study Design An orthotopic murine study utilizing University of Michigan squamous cell carcinoma-12 (UMSCC-12) laryngeal cancer cells was conducted in randomized controlled fashion with three treatment arms: saline, systemic cisplatin, and peritumoral HA-cisplatin. Methods UMSCC-12 laryngeal canc...περισσότερα »
Endostar for Locally Recurrent Nasopharyngeal Carcinoma
Endostar for Locally Recurrent Nasopharyngeal Carcinoma: *Condition*: Nasopharyngeal Carcinoma *Interventions*: Drug: Endostatins; Radiation: IMRT *Sponsors*: Sun Yat-sen University; JiangXi Province Tumor Hospital; The First Affiliated Hospital of Clinical Medicine of G.D.P.U.; Second Affiliated Hospital of Nanchang University; First People's Hospital of Foshan; Cancer Center of Guangzhou Medical University; The Affiliated GanZhou Hospital of NanChang University; The First Hospital of Gannan Medical University ArmsAssigned InterventionsActive Comparator: I... περισσότερα »
Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy
Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy: *Conditions*: Adult Solid Neoplasm; Bladder Carcinoma; Colon Carcinoma; Estrogen Receptor Negative; Head and Neck Squamous Cell Carcinoma; Hepatocellular Carcinoma; HER2/Neu Negative; Melanoma; Non-Small Cell Lung Carcinoma; Pancreatic Carcinoma; Progesterone Receptor Negative; Rectal Carcinoma; Renal Cell Carcinoma; Soft Tissue Sarcoma; Triple-Negative Breast Carcinoma *Interventions*: Other: Laboratory Biomarker Analysis; Biological: Modified ... περισσότερα »
Enadenotucirev and Pembrolizumab in Subjects With Metastatic or Advanced Epithelial Tumors
Study of Enadenotucirev and Pembrolizumab in Subjects With Metastatic or Advanced Epithelial Tumors: *Conditions*: Colorectal Cancer; Bladder Carcinoma; Squamous Cell Carcinoma of the Head and Neck; Salivary Gland Cancer *Interventions*: Biological: enadenotucirev; Biological: pembrolizumab *Sponsors*: PsiOxus Therapeutics Ltd; INC Research This is a Phase I multicenter, open label, nonrandomized study of enadenotucirev administered in combination with pembrolizumab in subjects with metastatic or advanced epithelial tumors (with focus on CRC, UCC, SCCHN and saliva...περισσότερα »
Operations for Lacrimal Duct Obstruction
Comparative Study of Two Operations for Lacrimal Duct Obstruction: *Condition*: Lacrimal Duct Obstruction *Interventions*: Procedure: Silicone Nasolacrimal Intubation; Procedure: Dacryocystorhinostomy *Sponsor*: Third Affiliated Hospital, Sun Yat-Sen University ArmsAssigned InterventionsExperimental: Silicone Nasolacrimal Intubation The silicone nasolacrimal intubation under nasal endoscopy is perferable, which is more simple and efficient. With endoscopy, the investigators can see anatomical structures clearly and then can perform the operation much more perfectly.Compare... περισσότερα »
Thyroid Autoantibodies in the Cerebrospinal Fluid of Subjects with and without Thyroid Disease: Implications for Hashimoto’s Encephalopathy
Thyroid Autoantibodies in the Cerebrospinal Fluid of Subjects with and without Thyroid Disease: Implications for Hashimoto’s Encephalopathy: Introduction. Plasma antithyroid peroxidase (anti-TPO) and anti-thyroglobulin antibodies (anti-Tg) are widely used in the diagnosis of autoimmune thyroiditis. No research has compared anti-TPO and anti-Tg both in plasma and cerebrospinal fluid (CSF) of healthy individuals vis-à-vis patients with thyroid disease. Methods. We measured anti-TPO and anti-Tg antibodies in plasma and CSF in nine subjects (mean age ± SD: 73 ± 6 years) with hypothyroid...περισσότερα »
What Would You Do? Baby who turned blue is now fine
What Would You Do? Baby who turned blue is now fine: In this episode, our experts discuss the condition known as an apparent life-threatening event (or an ALTE) and offer advice how to best handle an ALTE, even if the baby is no longer presenting symptoms that caused the 911 call. Dr. Tan describes the patient presenting symptoms and why it is important to transport an infant that has experienced an ALTE. Learn more about ALTEs in this scenario and solution ...
Hearing and tinnitus in head and neck cancer patients after chemoradiotherapy
Hearing and tinnitus in head and neck cancer patients after chemoradiotherapy: AbstractHead and neck cancer patients treated with high-dose cisplatin and radiotherapy will suffer from hearing deficits. The current low-dose regimen seldom causes hearing threshold decrease. Tinnitus in this patient population has not been investigated earlier. We aimed to evaluate the possible ototoxicity of low-dose (40 mg/m2) weekly administered cisplatin with concomitant radiotherapy. Twenty-two patients with locally advanced head and neck cancer were prospectively recruited to participate the stu...περισσότερα »
Laryngopharyngeal reflux disease in the general population, prevalence and risk factors
Laryngopharyngeal reflux disease in the Greek general population, prevalence and risk factors: Abstract BackgroundTo assess the prevalence of laryngopharyngeal reflux (LPR) in the Greek general population and its risk factors. MethodsQuestionnaire based epidemiological, adult participants’ survey. The Reflux Symptom Index (RSI) was used for the assessment of LPR prevalence. The RSI questionnaire was completed by 340 (183 male and 157 female) randomly selected subjects. Subjects with RSI score ≥13 were considered as LPR patients and those with RSI score <13 were considered as no... περισσότερα »
Injuries due to Foreign Body Aspirations
Injuries due to Foreign Body Aspirations in Georgia: A Prevention perspective: Suffocation due to foreign bodies (FB) is a leading cause of death in children aged 0–3. No data from the former U.S.S.R are available in the international scientific literature. AbstractBackground Suffocation due to foreign bodies (FB) is a leading cause of death in children aged 0–3. No data from the former U.S.S.R are available in the international scientific literature. Methods Consecutive patients admitted at the Iashvili Central Children Hospital in Tbilisi, Georgia from 1989 to 2011 were analyzed... περισσότερα »
Mannose Binding Lectin codon 54 polymorphism and susceptibility to recurrent respiratory tract infections in children: a meta-analysis
Mannose Binding Lectin codon 54 polymorphism and susceptibility to recurrent respiratory tract infections in children: a meta-analysis: There have been studies focused on mannose binding lectin (MBL) polymorphism and susceptibility to recurrent respiratory tract infections (RRTI) with inconclusive results. This present study is a meta-analysis of possible MBL and RRTI association in children. AbstractBackground There have been studies focused on mannose binding lectin (MBL) polymorphism and susceptibility to recurrent respiratory tract infections (RRTI) with inconclusive results.... περισσότερα »
Changes in body composition and growth pattern after adenotonsillectomy in prepubertal children
Changes in body composition and growth pattern after adenotonsillectomy in prepubertal children: Adenotonsillar hypertrophy and chronic tonsillitis are associated with growth interruption during childhood, while adenotonsillectomy has been associated with growth improvement and increased body mass index (BMI). However, no reported study has investigated the effect of adenotonsillectomy on the proportion of body muscle and fat mass. The aim of this prospective study was to evaluate the effect of adenoidectomy and adenotonsillectomy on body muscle and fat composition in prepubertal ch... περισσότερα »
Solitary Extramedullary Plasmacytoma of the Sphenoid Sinus: A Case Report
Solitary Extramedullary Plasmacytoma of the Sphenoid Sinus: A Case Report: AbstractSolitary extramedullary plasmacytomas are rare, discrete mass of neoplastic monoclonal plasma cells in the soft tissue with no evidence of multiple myeloma. They constitute 3 % of all plasma cell tumors and less than 1 % of head and neck malignancies. A 43 year old lady presented to our clinic with complains of diplopia and headache for 4 weeks. Computed Tomography scan showed a mass lesion in the sphenoid sinus eroding the sinus floor, right wall, basisphenoid and parasellar area. A biopsy of the ma...περισσότερα »
MM-398 (nanoliposomal irinotecan): emergence of a novel therapy for the treatment of advanced pancreatic cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 52 δευτερόλεπτα
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YxKdDU via IFTTT
Corrigendum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 52 δευτερόλεπτα
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YxKffc via IFTTT
Corrigendum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 52 δευτερόλεπτα
Future Oncology January 2016, Vol. 12, No. 2, Pages 272-272. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22mjGyh via IFTTT
Corrigendum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 52 δευτερόλεπτα
Future Oncology January 2016, Vol. 12, No. 1, Pages 138-138. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22mjGhC via IFTTT
Efficacy of intrathecal morphine for postoperative pain management following open nephrectomy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 52 δευτερόλεπτα
Objective To evaluate the efficacy and safety of intrathecal morphine (ITM) for postoperative pain control in patients with renal cell carcinoma undergoing open nephrectomy. Methods Forty-five patients scheduled for open nephrectomy were randomised to receive 300 µg ITM and intravenous patient-controlled analgesia (IV-PCA) (n = 22) or IV-PCA alone (n = 23) for postoperative analgesia. […]
Case Report on the Effects of Cognitive Processing Therapy on Psychological, Neuropsychological, and Speech Symptoms in Comorbid PTSD and TBI
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 53 δευτερόλεπτα
Publication date: Available online 21 December 2015 Source:Cognitive and Behavioral Practice Author(s): Briana Boyd, Carie Rodgers, Robin Aupperle, Amy Jak Both posttraumatic stress disorder (PTSD) and history of traumatic brain injury (TBI) are prevalent conditions in military veterans, frequently co-occur in this population, and have substantial symptom overlap. Cognitive processing therapy (CPT) is an empirically […]
Exposure to maternal smoking during pregnancy and risk of childhood cancer: a study using the Danish national registers
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 53 δευτερόλεπτα
Abstract Purpose The relation between maternal smoking during pregnancy and childhood cancer in the offspring remains uncertain. This paper uses Danish national registers, which have collected data prospectively on smoking and cancer, to investigate the association. Methods Smoking during pregnancy was ascertained from maternal self-reported data in the Danish National Patient Register. Index children were […]
Efficacy of intrathecal morphine for postoperative pain management following open nephrectomy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 53 δευτερόλεπτα
Objective To evaluate the efficacy and safety of intrathecal morphine (ITM) for postoperative pain control in patients with renal cell carcinoma undergoing open nephrectomy. Methods Forty-five patients scheduled for open nephrectomy were randomised to receive 300 µg ITM and intravenous patient-controlled analgesia (IV-PCA) (n = 22) or IV-PCA alone (n = 23) for postoperative analgesia. […]
Case Report on the Effects of Cognitive Processing Therapy on Psychological, Neuropsychological, and Speech Symptoms in Comorbid PTSD and TBI
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 53 δευτερόλεπτα
Publication date: Available online 21 December 2015 Source:Cognitive and Behavioral Practice Author(s): Briana Boyd, Carie Rodgers, Robin Aupperle, Amy Jak Both posttraumatic stress disorder (PTSD) and history of traumatic brain injury (TBI) are prevalent conditions in military veterans, frequently co-occur in this population, and have substantial symptom overlap. Cognitive processing therapy (CPT) is an empirically […]
Exposure to maternal smoking during pregnancy and risk of childhood cancer: a study using the Danish national registers
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 53 δευτερόλεπτα
Abstract Purpose The relation between maternal smoking during pregnancy and childhood cancer in the offspring remains uncertain. This paper uses Danish national registers, which have collected data prospectively on smoking and cancer, to investigate the association. Methods Smoking during pregnancy was ascertained from maternal self-reported data in the Danish National Patient Register. Index children were […]
Weaker compressions after night shift? The WeCAN manikin study
[image: image]To assess whether the quality of chest compressions (CC) differs before and after a night shift. We carried out a cluster randomized study in three Emergency Departments and three ICUs in Paris, France. Physicians were assessed on a control day and immediately following after a night shift. The primary endpoint was the proportion of CC with a depth greater than 50 mm. We analyzed 67 participants. The proportion of CC with a depth greater than 50 mm was similar on a control day and after a night shift [52% in both groups, mean difference of 0 (95% confidence interval: −...περισσότερα »
The predictive validity of RETTS-HEV as an acuity triage tool in the emergency department of a Danish Regional Hospital
[image: image]Introduction: The Rapid Emergency Triage and Treatment System – Hospital Unit West (RETTS-HEV) is a triage system used in the emergency department (ED) in Herning, Denmark, since 2010. It categorizes patients according to priority and defines a time limit on how long patients can wait before being seen by a doctor depending on the severity of their condition. The purpose of this study was to determine the predictive validity of RETTS-HEV by measuring the association between triage scores and outcomes such as the admission rate, the length of stay (LOS), and mortality. ...περισσότερα »
Evaluation of nasogastric tubes to enable differentiation between upper and lower gastrointestinal bleeding in unselected patients with melena
[image: image]Gastrointestinal (GI) bleeding is a common surgical problem. The aim of this study was to evaluate how insertion of the nasogastric tube may enable differentiation between upper and lower GI bleeding in patients with melena. A retrospective study involving patients admitted to our surgery division with a melena was carried out between the years 2010 and 2012. A total of 386 patients were included in the study. Of these, 279 (72.2%) patients had negative nasogastric aspirate. The sensitivity of examination of nasogastric aspirate to establish the upper GI as the source ... περισσότερα »
Blood cultures in emergency medical admissions: a key patient cohort
[image: image]Objectives: Blood cultures are performed in the emergency room when sepsis is suspected, and a cohort of patients is thereby identified. The present study investigated the outcomes (mortality and length of hospital stay) in this group following an emergency medical admission. Methods: Prospective assessment of all emergency medical admissions presenting to the emergency department at St James's Hospital, Dublin, over an 11-year period (2002–2012) was carried out. Outcomes including 30-day in-hospital mortality and length of stay were explored in the context of an admis...περισσότερα »
Barriers to focused echocardiography education
[image: image]No abstract available from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1ZmsSAd via IFTTT
Prediction of bacteremia in the emergency department: an external validation of a clinical decision rule
[image: image]Objective: The objective of this study was to validate a previously published clinical decision rule for predicting a positive blood culture in emergency department (ED) patients with suspected infection on the basis of major and minor criteria and a total score (Shapiro et al., J Emerg Med, 2008; 35:255–264). Methods: This is a retrospective matched cohort study of adult ED patients with blood cultures obtained from 1 January 2011 through to 31 December 2011. ED patients with blood culture-confirmed bacteremia were matched 1 : 3 with patients with negative cultures. T... περισσότερα »
Protocol for a single-centre randomised controlled trial of multimodal periarticular anaesthetic infiltration versus single-agent femoral nerve blockade as analgesia for total knee arthroplasty: Perioperative Analgesia for Knee Arthroplasty (PAKA)
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Introduction Total knee arthroplasty (TKA) surgery causes postoperative pain. The use of perioperative injections around the knee containing local anaesthetic, opiates and non-steroidal anti-inflammatory drugs has increased in popularity to manage pain. Theoretical advantages include reduced requirements for analgesia and earlier mobilisation. We propose a single-centre randomised controlled trial of multimodal periarticular anaesthetic infiltration versus […]
Collaborative care for comorbid depression and coronary heart disease: a systematic review and meta-analysis of randomised controlled trials
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives To systematically review the efficacy of collaborative care (CC) for depression in adults with coronary heart disease (CHD) and depression. Design Systematic review and meta-analysis. Data sources Electronic databases (Cochrane Central Register of Controlled Trials MEDLINE, EMBASE, PsycINFO and CINAHL) were searched until April 2014. Inclusion criteria Population, depression comorbid with CHD; intervention, randomised […]
The spectrum of unhealthy drug use and quality of care for hypertension and diabetes: a longitudinal cohort study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives Although it is well known that addiction is associated with adverse medical consequences, the effects of the spectrum of unhealthy drug use (illicit drug or prescription misuse) on chronic conditions such as hypertension and diabetes are understudied. This study evaluated the associations between measures of drug use (ie, frequency, severity and type) and standard […]
Relationship of anthropometric measurements to thyroid nodules in a Chinese population
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective Previous studies have found that overweight and obesity are related to numerous diseases, including thyroid cancer and thyroid volume. This study evaluates the relationship between body size and the presence of thyroid nodules in a Chinese population. Methods A total of 6793 adults and 2410 children who underwent thyroid ultrasonography were recruited in this […]
Symptom burden, Metabolic profile, Ultrasound findings, Rhythm, neurohormonal activation, haemodynamics and health-related quality of life in patients with atrial Fibrillation (SMURF): a protocol for an observational study with a randomised interventional component
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Introduction Atrial fibrillation (AF) is the most common cardiac arrhythmia, with an estimated prevalence of 1.5–2%. It is an independent risk factor for ischaemic stroke and is estimated to cause about 20–25% of all stroke cases. AF has a great impact on health-related quality of life (HRQoL); however, one unresolved issue related to AF is […]
Barriers to early presentation of self-discovered breast cancer in Singapore and Malaysia: a qualitative multicentre study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective To explore and compare barriers to early presentation of self-discovered breast cancer in Singapore and Malaysia. Design A qualitative interview study with thematic analysis of transcripts. Participants 67 patients with self-discovered breast symptoms were included in the analysis. Of these, 36% were of Malay ethnicity, 39% were Chinese and 25% Indian, with an average […]
Dementia risk estimates associated with measures of depression: a systematic review and meta-analysis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives To perform a systematic review of reported HRs of all cause dementia, Alzheimer’s disease (AD) and vascular dementia (VaD) for late-life depression and depressive symptomatology on specific screening instruments at specific thresholds. Design Meta-analysis with meta-regression. Setting and participants PubMed, PsycInfo, and Cochrane databases were searched through 28 February 2014. Articles reporting HRs for […]
Environmental Health and Preventive Medicine
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Te7BoP via IFTTT
Immunotherapies in Alzheimer’s disease: Too much, too little, too late or off-target?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Years of research have highlighted the importance of the immune system in Alzheimer’s disease (AD), a system that, if manipulated during strategic time windows, could potentially be tackled to treat this disorder. However, to minimize adverse effects, it is essential to first grasp which exact aspect of it may be targeted. Several clues have […]
Ten-year trends of syphilis in sero-surveillance of pregnant women in Rwanda and correlates of syphilis-HIV co-infection
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Syphilis can be transmitted by pregnant women to their children and is a public health problem in Africa. A cross-sectional survey was conducted in 24 antenatal clinics from 2002 to 2003 and increased to 30 sites from 2005 to 2011. Participants were tested for syphilis and HIV. Multi-variate logistic regression was performed to identify risks […]
Solitary Extramedullary Plasmacytoma of the Sphenoid Sinus: A Case Report
Abstract Solitary extramedullary plasmacytomas are rare, discrete mass of neoplastic monoclonal plasma cells in the soft tissue with no evidence of multiple myeloma. They constitute 3 % of all plasma cell tumors and less than 1 % of head and neck malignancies. A 43 year old lady presented to our clinic with complains of diplopia …
Mesothelial Cells Within Vascular Transformation of Mediastinal Lymph Node Sinuses: An Unusual Benign Collision Mimicking Colliding Malignancies
Vascular transformation of lymph node sinuses represents a rare benign entity mimicking malignant counterparts such as nodal Kaposi sarcoma. The presence of mildly atypical benign mesothelial cells within nodal sinuses raises the possibility of metastatic malignancy. Herein, a rare case of vascular transformation of lymph node sinuses with reactive sinusoidal mesothelial cells is outlined as …
Parent verbal contingencies during the Lidcombe Program: Observations and statistical modeling of the treatment process
Publication date: Available online 21 December 2015 Source:Journal of Fluency Disorders Author(s): Michelle C. Swift, Mark Jones, Sue O’Brian, Mark Onslow, Ann Packman, Ross Menzies PurposeThe purpose of this study was to document parent presentation of the Lidcombe Program verbal contingencies and model potential relationships between contingency provision and treatment duration.MethodsForty parent-child pairs undertaking the …
Surgical Value of Elective Minimally Invasive Gallbladder Removal: A Cost Analysis of Traditional 4-Port vs Single-Incision and Robotically-Assisted Cholecystectomy
As the cost of healthcare is subjected to increasingly greater scrutiny, the assessment of new technologies must include the surgical value (SV) of the procedure. SV is defined as outcome divided by cost. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OHuw81 via IFTTT
Ten-year trends of syphilis in sero-surveillance of pregnant women in Rwanda and correlates of syphilis-HIV co-infection
Syphilis can be transmitted by pregnant women to their children and is a public health problem in Africa. A cross-sectional survey was conducted in 24 antenatal clinics from 2002 to 2003 and increased to 30 sites from 2005 to 2011. Participants were tested for syphilis and HIV. Multi-variate logistic regression was performed to identify risks …
Prognostic Molecular Subtypes of Low-Grade Cancer of the Appendix
Appendiceal cancer (AC) patients treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) often demonstrate an unpredictable variability in survival outcomes. Biomarkers predictive of CRS/HIPEC efficacy could better guide treatment decisions. Herein, we hypothesized that variation in the transcriptional programming of AC tumors might distinguish molecular subtypes with differential outcomes after CRS/HIPEC. from #Medicine-SfakianakisAlexandros …
Resurrection of the Comoran fish scale gecko Geckolepis humbloti Vaillant, 1887 reveals a disjunct distribution caused by natural overseas dispersal
Abstract Fish scale geckos (Geckolepis) are taxonomically poorly resolved, mainly because of the difficulty of applying standard morphological characters to diagnose taxa. Three species, Geckolepis maculata, G. polylepis, and G. typica, are currently recognized from Madagascar and the Comoro Islands. Molecular studies suggested a number of operational taxonomical units within the G. maculata complex, but …
Transformation: A New Kind of Academic Health Center and the Pursuit of High Self-Mastery
Above all, this address is about transformation—the process of completely changing one configuration into another. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1IlushI via IFTTT
Mercury, lead, and cadmium in tissues of the Caspian Pond Turtle ( Mauremys caspica ) from the southern basin of Caspian Sea
Abstract Concentrations of cadmium, lead, and mercury were measured in different tissues (liver, muscle, and shell) of 60 Caspian Pond Turtles collected from Tajan and Shiroud Rivers, southern basin of the Caspian Sea. Based on the results, different tissues showed different capacities for accumulating trace elements. The general trend of metals accumulation was: liver > shell > muscle. Results …
Outcomes of Adjuvant Mitotane after Resection of Adrenocortical Carcinoma: A 13-Institution Study by the US Adrenocortical Carcinoma Group
Current treatment guidelines recommend adjuvant mitotane after resection of adrenocortical carcinoma with high-risk features (tumor rupture, positive margins, positive lymph nodes, high grade, elevated mitotic index, and advanced stage). Limited data exist on the outcomes associated with these practice guidelines. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Ilupm6 via IFTTT
The Dilator Naris Muscle as a Reporter of Facial Nerve Regeneration in a Rat Model
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective: Many investigators study facial nerve regeneration using the rat whisker pad model, although widely standardized outcomes measures of facial nerve regeneration in the rodent have not yet been developed. The intrinsic whisker pad “sling” muscles producing whisker protraction, situated at the base of each individual whisker, are extremely small and difficult to study en […]
Book Review
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from Aesthetic via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RBxvFg via IFTTT
Reverse Superior Labial Artery Flap in Reconstruction of Nose and Medial Cheek Large Defects
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from Aesthetic via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RBxykn via IFTTT
Extracorporeal Septoplasty Combined With Valve Surgery in Rhinoplasty Patients
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract: External nasal deviation is caused primarily by severely a deformed septum. The nose functions as a whole composed of the septum, valve systems, and mucosal structures. Patients with severely deviated septums also have deformed nasal valve systems. Extracorporeal septoplasty is advocated for an extremely deviated nasal septum. Nasal valve dysfunctions can be resolved successfully […]
Amputation Stump Revision Using a Free Sural Neurocutaneous Perforator Flap
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background: The development of microsurgery and the concept of the surgical flap have enabled orthopedic surgeons to deal with various soft tissue defects and compositions during limb salvage procedures. However, severely damaged bony structures with accompanying soft tissue deficiencies often result in amputation. When performing amputations, surgeons must preserve the stump length to maximize functional […]
The Outcome of Primary Subglandular Breast Augmentation Using Tumescent Local Anesthesia
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background: Tumescent local anesthesia (TLA) technique to obtain regional anesthesia and vasoconstriction of the skin and subcutaneous tissues is routinely adopted for several plastic surgery procedures. Here, we describe the use of TLA in primary subglandular breast augmentation. This series evaluates advantages and disadvantages of TLA in elective augmentation breast surgery as well as patients’ […]
Correcting Glanular Dislocation in Hypospadias With Up-to-Tip Technique and Double Wing Flaps
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background: The surgical treatment of hypospadias contains urethral reconstruction and correction of penile curvature. In some severe type of hypospadias, it also needs correction of penoscrotal transposition and cleft of scrotum. However, there are few literatures that refer to the correcting of deformity of glanular dislocation. Objective: This study aimed to correct the deformity of […]
Management of a Common Breast Augmentation Complication: Treatment of the Double-Bubble Deformity With Fat Grafting
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract: The double-bubble deformity is one of the most common problems in breast augmentation, with or without mastopexy. Classically, open techniques have been used to treat this deformity, including elevation and reconstruction of the inframammary crease or parenchymal scoring. In this study, the author reports experience with a simple, closed technique of serial fat grafting […]
A Standardized Method of Isolating Adipose-Derived Stem Cells for Clinical Applications
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract: White adipose tissue is the most abundant and accessible source of stem cells in the adult human body. In this paper, we present a standardised and safe method of isolating and maximizing the number of adipose-derived stem cells (ASCs) from conventional liposuction for clinical applications, which was carried out through both mechanical (centrifuge) and […]
Profile of language and cognitive functions in children with dyslexia in speakers of Brazilian Portuguese
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
RESUMO Objetivo: Verificar o perfil de linguagem e de habilidades cognitivas de crianças com dislexia, contribuindo para o diagnóstico desse quadro em leitores de uma ortografia regular, como o português brasileiro. Métodos: Participaram do estudo 47 crianças com dislexia (GD), 41 crianças pareadas por idade (GCI) e 31 crianças pareadas por nível de leitura (GCL), […]
Influence of pharyngeal flap surgery on nasality and nasalance scores of nasal sounds production in individuals with cleft lip and palate
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
RESUMO Objetivo: Verificar a influência da cirurgia de retalho faríngeo para a correção da insuficiência velofaríngea sobre a nasalidade e a nasalância da fala na produção de sons nasais de indivíduos com fissura labiopalatina. Métodos Estudo prospectivo realizado com 159 indivíduos com fissura de palato±lábio reparada, de ambos os gêneros, com idades entre 6 e […]
Voice, stress, work and quality of life of soccer coaches and physical trainers
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
RESUMO Objetivos: Avaliar aspectos relacionados a estresse, trabalho e qualidade de vida em voz de técnicos (T) e preparadores físicos de futebol (P), comparando as categorias. Métodos: Estudo qualitativo e quantitativo com 13 T e 13 P de times da primeira fase do Campeonato Paulista de Futebol 2012/série A. Foram realizadas perguntas abertas referentes a […]
Efficiency and cutoff values of the Voice Activity and Participation Profile for nonteachers and teachers
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
RESUMO Objetivos: Identificar características de eficiência e valores de corte das dimensões do protocolo Perfil de Participação e Atividades Vocais – PPAV que discriminam disfônicos de indivíduos vocalmente saudáveis; verificar se a nota de corte permanece a mesma para uma amostra de professores. Métodos: Características de eficiência e valores de corte dos dados do PPAV […]
Myofunctional therapy applied to upper airway resistance syndrome: a case report
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
RESUMO A literatura contempla publicações sobre o tratamento de pacientes com Síndrome da Apneia Obstrutiva do Sono (SAOS) por meio da terapia miofuncional orofacial, porém não há relatos dessa abordagem para pacientes com Síndrome do Aumento da Resistência das Vias Aéreas Superiores (SARVAS). O objetivo deste trabalho foi verificar o efeito da terapia miofuncional orofacial […]
Tools for the assessment of childhood apraxia of speech
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
RESUMO Objetivo: Revisar sistematicamente na literatura os principais instrumentos utilizados para avaliação da apraxia de fala infantil. Estratégia de pesquisa: Realizou-se busca nas bases Scopus, PubMed e Embase Critérios de seleção: Foram selecionados estudos empíricos que utilizaram instrumentos de avaliação da apraxia de fala infantil. Análise dos dados: A seleção dos artigos foi realizada por […]
Training of Community Health Agents in health hearing children: current perspectives
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
RESUMO Objetivo: Caracterizar a capacitação dos Agentes Comunitários de Saúde (ACS) na área da saúde auditiva infantil. Estratégia de pesquisa Foi realizada uma revisão sistemática da literatura no Portal de Pesquisa da Biblioteca Virtual em Saúde (BVS) e na Biblioteca Digital de Teses e Dissertações da USP. Critérios de seleção: A estratégia de busca foi […]
Comparative effectiveness of onabotulinumtoxinA versus oral migraine prophylactic medications on headache-related resource utilization in the management of chronic migraine: Retrospective analysis of a US-based insurance claims database
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background Migraine, especially chronic migraine (CM), causes substantial disability; however, health care utilization has not been well characterized among patients receiving different migraine prophylactic treatments. Methods Using a large, US-based, health care claims database, headache-related health care utilization was evaluated among adults with CM treated with onabotulinumtoxinA or oral migraine prophylactic medications (OMPMs). Headache-related health […]
Management, reconstruction and rehabilitation of a periorbital necrotising fasciitis
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Necrotising fasciitis (NF) is a relatively uncommon but serious condition with a real risk of death. It is characterised by a rapidly progressing necrotising infection of fascial layers. It is commonly associated with a Group A streptococcal infection. Cases affecting the face are less common due to its superior blood supply. Periorbital NF can result […]
Is CT imaging of the facial skeleton in trauma inadequate? How can inadequacies be overcome?
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Introduction: There are 180,000 serious facial injuries annually, many of which form part of polytrauma. Computed tomography (CT) plays an important role in the initial imaging of these patients due to potential C-spine and head injuries. Scanning protocols do not demonstrate the entire facial skeleton in all cases. Further imaging is necessary if injuries cannot […]
Software-based on-site estimation of fractional flow reserve using standard coronary CT angiography data
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Background The significance of a coronary stenosis can be determined by measuring the fractional flow reserve (FFR) during invasive coronary angiography. Recently, methods have been developed which claim to be able to estimate FFR using image data from standard coronary computed tomography angiography (CCTA) exams. Purpose To evaluate the accuracy of non-invasively computed fractional flow […]
Multidetector computed tomographic assessment of the normal diameters for the thoracic aorta and pulmonary arteries in infants and children
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Background Knowledge of the normal size of the thoracic aorta and pulmonary arteries is important regarding the detection of the abnormal and valuable in the treatment of patients with congenital and acquired cardiovascular diseases. Purpose To determine the normal diameters of the thoracic vascular structures of pediatric participants on contrast-enhanced multidetector computer tomography (MDCT) scans. […]
An Unexpected Pulmonary Coin Lesion
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Te0Jrs via IFTTT
Mesothelial Cells Within Vascular Transformation of Mediastinal Lymph Node Sinuses: An Unusual Benign Collision Mimicking Colliding Malignancies
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Vascular transformation of lymph node sinuses represents a rare benign entity mimicking malignant counterparts such as nodal Kaposi sarcoma. The presence of mildly atypical benign mesothelial cells within nodal sinuses raises the possibility of metastatic malignancy. Herein, a rare case of vascular transformation of lymph node sinuses with reactive sinusoidal mesothelial cells is outlined as […]
Surgical Value of Elective Minimally Invasive Gallbladder Removal: A Cost Analysis of Traditional 4-Port vs Single-Incision and Robotically-Assisted Cholecystectomy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
As the cost of healthcare is subjected to increasingly greater scrutiny, the assessment of new technologies must include the surgical value (SV) of the procedure. SV is defined as outcome divided by cost. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OHuw81 via IFTTT
Prognostic Molecular Subtypes of Low-Grade Cancer of the Appendix
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Appendiceal cancer (AC) patients treated with cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) often demonstrate an unpredictable variability in survival outcomes. Biomarkers predictive of CRS/HIPEC efficacy could better guide treatment decisions. Herein, we hypothesized that variation in the transcriptional programming of AC tumors might distinguish molecular subtypes with differential outcomes after CRS/HIPEC. from #Medicine-SfakianakisAlexandros […]
Transformation: A New Kind of Academic Health Center and the Pursuit of High Self-Mastery
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Above all, this address is about transformation—the process of completely changing one configuration into another. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1IlushI via IFTTT
Outcomes of Adjuvant Mitotane after Resection of Adrenocortical Carcinoma: A 13-Institution Study by the US Adrenocortical Carcinoma Group
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Current treatment guidelines recommend adjuvant mitotane after resection of adrenocortical carcinoma with high-risk features (tumor rupture, positive margins, positive lymph nodes, high grade, elevated mitotic index, and advanced stage). Limited data exist on the outcomes associated with these practice guidelines. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Ilupm6 via IFTTT
Elevated Plasma Pancreastatin, But Not Chromogranin A, Predicts Survival in Neuroendocrine Tumors Of The Duodenum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Duodenal neuroendocrine tumors are rare, heterogenous, and often classified as indolent neoplasms. Our study shows that elevated pancreastatin can identify patients with a poor prognosis. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OHutZU via IFTTT
Trends in Follow-up of Patients Presenting to the Emergency Department with Symptomatic Cholelithiasis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Fewer than 25% of Medicare beneficiaries presenting with symptomatic cholelithiasis undergo elective cholecystectomy. To better understand underuse of cholecystectomy, we examined physician follow-up patterns after emergency department (ED) visits for symptomatic gallstones. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OHutcp via IFTTT
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