Patient movement and motion artefacts in cone beam computed tomography
of the dentomaxillofacial region: a systematic literature review via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 19 December 2015 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Rubens Spin-Neto, Ann Wenzel ObjectivesTo undertake a systematic review on the current knowledge regarding patient movement detection and patient motion artefacts related to CBCT imaging of the dentomaxillofacial region.MethodsThe MEDLINE (PubMed) bibliographic database was searched until June 2015 for studies evaluating pa... περισσότερα »
Low-level laser therapy vs. 5% Amlexanox for minor aphthous ulcers
Low-level laser therapy vs. 5% Amlexanox: A comparison of treatment effects in a cohort of minor aphthous ulcers patients via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 19 December 2015 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): M.J. Jijin, Mangala Rakaraddi, Jagadish Pai, H.P. Jaishankar, R. Krupashankar, A.P. Kavitha, R. Anjana, R. Shobha ObjectiveThe aim of the study was to compare the treatment effects of 5% Amlexanox and low-level laser therapy (LLLT) in a cohort of patients who experienc...περισσότερα »
Keratins 6, 7, 8, 14, 16, 18, 19 and MNF-116 pancytokeratin in primary and metastatic melanoma of the head and neck
Immunohistochemical expression of via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 19 December 2015 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Rima A. Safadi, Dima H. Bader, Niveen I. Abdullah, Maher A. Sughayer ObjectiveTo investigate the immunohistochemical expressions (IHCE) of selected keratins in primary cutaneous and mucosal melanoma (pM), and metastatic melanoma (metsM) of the head and neck and to compare their expressions in a group of undifferentiated/poorly differentiated tumors of t... περισσότερα »
Salivary parameters of children with juvenile idiopathic arthritis
Compromised via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 19 December 2015 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Bruna de Oliveira Perestrelo, Alice Rodrigues Feres de Melo, Giselle Rodrigues de Sant’Anna, Mariana Ferreira Leite ObjectiveTo evaluate the salivary parameters of individuals with juvenile idiopathic arthritis (JIA) and determine if a correlation existed with the simplified oral hygiene index (OHI-S).Study DesignStimulated whole saliva was collected from children aged 6-12 y...περισσότερα »
Tufted angioma of the maxilla
: a rare case with unique clinical presentation via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 19 December 2015 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Nikolaos Katsoulas, Nikolaos Nikitakis, Nadia Theologie-Lygidakis, Violetta Lianou, Konstantinos Tsiklakis, Ioannis Iatrou, Alexandra Sklavounou-Andrikopoulou Tufted angioma is an uncommon benign vascular tumor usually presenting in early childhood and affecting mainly the skin. It has been associated with Kasabach-Merritt syndrome, a severe... περισσότερα »
Distant metastasis in patients with squamous cell carcinoma of the oral cavity
Risk factors of via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 19 December 2015 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Yuki Sakamoto, Yuki Matsushita, Shin-ichi Yamada, Souich Yanamoto, Takeshi Shiraishi, Izumi Asahina, Masahiro Umeda ObjectiveAlthough the locoregional control rate of oral cancer has improved recently, the number of patients developing distant metastasis (DM) has increased. The aim of this study is to investigate the clinicopathological factors related to DM in patients w...περισσότερα »
The role of elective superficial parotidectomy in the treatment of temporal region squamous cell carcinoma
The role of elective superficial parotidectomy in the treatment of temporal region squamous cell carcinoma: Abstract ObjectiveIn order to determine rates of metastasis and efficacy of elective superficial parotidectomy, we examine parotid specimens in patients with temporal region cutaneous squamous cell carcinoma treated with local excision and ipsilateral parotidectomy. Study designThis paper is a retrospective review. SettingThis study was conducted at a private tertiary referral practice in Fort Worth, Texas, from 1998 to 2013. Subjects and methodsNinety-three patien... περισσότερα »
Dermoscopic clues to differentiate facial lentigo maligna from pigmented actinic keratosis
Dermoscopic clues to differentiate facial lentigo maligna from pigmented actinic keratosis: Summary Background The limitations of dermoscopy to accurately differentiate between pigmented lentigo maligna (LM) and pigmented actinic keratosis (PAK) might be related to the fact that most studies have focused on pigmented criteria only, without considering additional recognizable features. Objective To investigate the diagnostic accuracy of established dermoscopic criteria for pigmented LM and PAK, but including in the evaluation features previously associated with non-pigmented facial A...περισσότερα »
Neoadjuvant preoperative paclitaxel/cisplatin/radiotherapy (RT) or irinotecan/cisplatin/RT in esophageal adenocarcinoma
Eastern Cooperative Oncology Group (E1201) randomized phase II trial of neoadjuvant preoperative paclitaxel/cisplatin/radiotherapy (RT) or irinotecan/cisplatin/RT in esophageal adenocarcinoma: long term outcome and implications for trial design via International Journal of Radiation Oncology*Biology*Physics Publication date: Available online 18 December 2015 *Source:*International Journal of Radiation Oncology*Biology*Physics Author(s): Lawrence R. Kleinberg, Paul Catalano, Arlene A. Forastiere, Steven M. Keller, Edith P. Mitchel., Pramila Rani Anne, Al B. Benson BackgroundToxicity, pa... περισσότερα »
Talks in the city of light generate more heat
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
Rather than relying on far-off negative-emissions technologies, Paris needed to deliver a low-carbon road map for today, argues Kevin Anderson. Nature 528 437 doi: 10.1038/528437a from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1TciuYf via IFTTT
“Gazing into the synaptic chasm”: the Brain in Beckett’s Writing
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
Abstract This paper argues that Samuel Beckett’s interest in functions of the brain is not only evidenced in his notebooks, taken from a number of psychology and psycho-physiognomy texts in the early 1930s, but is also explored and expanded in his fiction and drama. This paper investigates Beckett’s fascination with the limits of “cerebral consciousness” […]
Rethinking the Poverty-disease Nexus: the Case of HIV/AIDS in South Africa
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
Abstract While it is well-established that poverty and disease are intimately connected, the nature of this connection and the role of poverty in disease causation remains contested in scientific and social studies of disease. Using the case of HIV/AIDS in South Africa and drawing on a theoretically grounded analysis, this paper reconceptualises disease and poverty […]
Eine EK-Transfusion verdoppelt Myokardinfarktrisiko
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
Eine Konserve ist keine Konserve? Eine individuell abgestimmte Verabreichung von Erythrozytenkonzentraten ist in bestimmten Situationen, wie z. B. bei akutem massivem Blutverlust oder bei Patienten mit hämatopoetischen Störungen absolut lebensrettend. Die Gabe von EK birgt allerdings Risiken, die u. U. krankheitsfördernd und lebensbedrohlich sein können. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1IjOby4 via IFTTT
Kein Beleg für Post-Lyme-Syndrom bei behandelten Patienten
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
Nach Erythema migrans Noch zehn oder mehr Jahre nach Auftreten eines Borreliose-bedingten Erythema migrans klagen manche Patienten trotz initialer Behandlung über unspezifische Beschwerden. Infektiologen aus den USA haben untersucht, was davon zu halten ist. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Zl347G via IFTTT
Eine EK-Transfusion verdoppelt Myokardinfarktrisiko
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
Eine Konserve ist keine Konserve? Eine individuell abgestimmte Verabreichung von Erythrozytenkonzentraten ist in bestimmten Situationen, wie z. B. bei akutem massivem Blutverlust oder bei Patienten mit hämatopoetischen Störungen absolut lebensrettend. Die Gabe von EK birgt allerdings Risiken, die u. U. krankheitsfördernd und lebensbedrohlich sein können. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1IjOby4 via IFTTT
Kein Beleg für Post-Lyme-Syndrom bei behandelten Patienten
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
Nach Erythema migrans Noch zehn oder mehr Jahre nach Auftreten eines Borreliose-bedingten Erythema migrans klagen manche Patienten trotz initialer Behandlung über unspezifische Beschwerden. Infektiologen aus den USA haben untersucht, was davon zu halten ist. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Zl347G via IFTTT
Genes, Vol. 6, Pages 1347-1360: Disruption of the Gut Microbiome: Clostridium difficile Infection and the Threat of Antibiotic Resistance
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
Clostridium difficile is well recognized as the leading cause of antibiotic-associated diarrhea, having a significant impact in both health-care and community settings. Central to predisposition to C. difficile infection is disruption of the gut microbiome by antibiotics. Being a Gram-positive anaerobe, C. difficile is intrinsically resistant to a number of antibiotics. Mobile elements encoding antibiotic […]
Genes, Vol. 6, Pages 1330-1346: Transcriptomic Analysis of the Porcine Endometrium during Embryo Implantation
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
In pigs, successful embryo implantation is an important guarantee for producing litter size, and early embryonic loss occurring on day 12–30 of gestation critically affects the potential litter size. The implantation process is regulated by the expression of numerous genes, so comprehensive analysis of the endometrium is necessary. In this study, RNA sequencing (RNA-Seq) technology […]
Genes, Vol. 6, Pages 1315-1329: Molecular Modeling of Myrosinase from Brassica oleracea: A Structural Investigation of Sinigrin Interaction
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
Myrosinase, which is present in cruciferous plant species, plays an important role in the hydrolysis of glycosides such as glucosinolates and is involved in plant defense. Brassicaceae myrosinases are diverse although they share common ancestry, and structural knowledge about myrosinases from cabbage (Brassica oleracea) was needed. To address this, we constructed a three-dimensional model structure […]
The role of Card9 overexpression in peripheral blood mononuclear cells from patients with aseptic acute pancreatitis
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Abstract Activated mononuclear cells are an early event in the course of severe acute pancreatitis (SAP). To date, the molecular mechanism triggering peripheral blood mononuclear cells (PBMCs) is poorly understood. The aim of this paper was to determine the potential role of Card9 in SAP. We collected data from 72 subjects between January 2013 and June 2014. Subsequently, PBMCs were isolated on day 1, 3 and 5 of pancreatitis. Immunofluorescence staining, quantitative real-time PCR, Western blotting, immunoprecipitation and ELISA were used to determine the role of Card9 in SAP. Mic...περισσότερα »
A systematic evaluation of field-based screening methods for the assessment of anterior cruciate ligament (ACL) injury risk
Sports Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1J1Nxph via IFTTT
Lesson from the New York City out-of-hospital uncontrolled donation after circulatory determination of death program
Annals of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1J1Nw4r via IFTTT
Virtual chromoendoscopy improves the diagnostic yield of small bowel capsule endoscopy in obscure gastrointestinal bleeding
Digestive and Liver Diseases from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TZzPng via IFTTT
Susceptibility vessel sign on MRI predicts favorable clinical outcome in patients with anterior circulation acute stroke treated with mechanical thrombectomy
American Journal of Neuroradiology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TZzPDC via IFTTT
Intelligent emergency department: Validation of sociometers to study workload
Journal of Medical Systems from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1J1Nw4x via IFTTT
Medical complications during pregnancy and childbirth in women with SCI in Switzerland
Spinal Cord from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TZzPnc via IFTTT
Creating a geriatric-focused model of care in trauma with geriatric education
Journal of Trauma Nursing from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TZzP6I via IFTTT
Effect of collaterals on clinical presentation, baseline imaging, complications, and outcome in acute stroke
American Journal of Neuroradiology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1J1Nx8D via IFTTT
Outcomes and mortality in renal transplant recipients admitted to the intensive care unit
Transplantation Proceedings from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TZzOj9 via IFTTT
Characteristics of neuropathic pain and its relationship with quality of life in 72 patients with spinal cord injury
Spinal Cord from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1J1NvO6 via IFTTT
Epidemiological trends in search and rescue incidents documented by the Alpine Club of Canada from 1970 to 2005
Wilderness & Environmental Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1J1Nx8s via IFTTT
Outcomes of less intensive glycemic target for a subcutaneous insulin protocol in hospitalized patients
The American Journal of the Medical Sciences from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TZzNvJ via IFTTT
Doctors: Epilepsy deaths should be public health priority
American Academy of Neurology News from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1J1NwSe via IFTTT
Molecules, Vol. 20, Pages 22900-22907: Guignardones P–S, New Meroterpenoids from the Endophytic Fungus Guignardia mangiferae A348 Derived from the Medicinal Plant Smilax glabra
Four new meroterpenoids, guignardones P–S (1–4), and three known analogues (5–7) were isolated from the endophytic fungal strain Guignardia mangiferae A348. Their structures were elucidated on the basis of spectroscopic analysis and single crystal X-ray diffraction. All the isolated compounds were evaluated for their inhibitory effects on SF-268, MCF-7, and NCI-H460 human cancer cell lines. Compounds 2 and 4 exhibited weak inhibitions of cell proliferation against MCF-7 cell line. from #Medicine via ola Kala on Inoreader http://ift.tt/1UW0YIG via IFTTT
Highly-sensitive organophosphorus pesticide biosensors based on CdTe quantum dots and bi-enzyme immobilized eggshell membranes
[image: GA?id=C5AN02163D] *Analyst*, 2016, Advance Article *DOI*: 10.1039/C5AN02163D, Paper Gao Xue, Zhao Yue, Zhang Bing, Tang Yiwei, Liu Xiuying, Li Jianrong An optical biosensing method using CdTe quantum dots (QDs) and bi-enzyme-immobilized eggshell membranes for the determination of organophosphorus pesticides (OPs) has been developed. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/1Pg2D9Z via IFTTT
Differential cellular localization of Epstein–Barr virus and human cytomegalovirus in the colonic mucosa of patients with active or quiescent inflammatory bowel disease
Immunologic Research from #Medicine via ola Kala on Inoreader http://ift.tt/1S4uX1G via IFTTT
Effect of sanitation and water treatment on intestinal protozoa infection: A systematic review and meta-analysis
The Lancet Infectious Diseases from #Medicine via ola Kala on Inoreader http://ift.tt/1TcePth via IFTTT
C-reactive protein level is an indicator of the aggressiveness of advanced pancreatic cancer
Pancreas from #Medicine via ola Kala on Inoreader http://ift.tt/1S4uUmw via IFTTT
Methotrexate for the management of Crohn's disease in children
Annals of Pharmacotherapy from #Medicine via ola Kala on Inoreader http://ift.tt/1S4uX1w via IFTTT
Diaphragmatic breathing for rumination syndrome: efficacy and mechanisms of action
Neurogastroenterology & Motility from #Medicine via ola Kala on Inoreader http://ift.tt/1TcePcP via IFTTT
Efficacy and safety of alternating norfloxacin and rifaximin as primary prophylaxis for spontaneous bacterial peritonitis in cirrhotic ascites: a prospective randomized open-label comparative multicenter study
Hepatology International from #Medicine via ola Kala on Inoreader http://ift.tt/1S4uWL6 via IFTTT
Hepatitis C virus NS4B can suppress sting accumulation to evade innate immune responses
Journal of Virology from #Medicine via ola Kala on Inoreader http://ift.tt/1TcePcG via IFTTT
Nonalcoholic fatty liver disease is associated with an almost two-fold increased risk of incident type 2 diabetes and metabolic syndrome. Evidence from a systematic review and meta-analysis
Journal of Gastroenterology and Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1S4uWuG via IFTTT
Virtual chromoendoscopy improves the diagnostic yield of small bowel capsule endoscopy in obscure gastrointestinal bleeding
Digestive and Liver Diseases from #Medicine via ola Kala on Inoreader http://ift.tt/1TceO8D via IFTTT
Assessment of energy requirements in patients with short bowel syndrome by using the doubly labeled water method
American Journal of Clinical Nutrition from #Medicine via ola Kala on Inoreader http://ift.tt/1S4uTPz via IFTTT
Holiday Dinner, With False Memories for Dessert
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Proceed with extreme caution when your family starts to share recollections about you that you yourself don’t remember
Kan ebola smitte seksuelt?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Ebola-RNA kan påvises i sæd i flere måneder etter gjennomgått ebolasykdom. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Mr6tby via IFTTT
Genes, Vol. 6, Pages 1347-1360: Disruption of the Gut Microbiome: Clostridium difficile Infection and the Threat of Antibiotic Resistance
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Clostridium difficile is well recognized as the leading cause of antibiotic-associated diarrhea, having a significant impact in both health-care and community settings. Central to predisposition to C. difficile infection is disruption of the gut microbiome by antibiotics. Being a Gram-positive anaerobe, C. difficile is intrinsically resistant to a number of antibiotics. Mobile elements encoding antibiotic […]
Genes, Vol. 6, Pages 1330-1346: Transcriptomic Analysis of the Porcine Endometrium during Embryo Implantation
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
In pigs, successful embryo implantation is an important guarantee for producing litter size, and early embryonic loss occurring on day 12–30 of gestation critically affects the potential litter size. The implantation process is regulated by the expression of numerous genes, so comprehensive analysis of the endometrium is necessary. In this study, RNA sequencing (RNA-Seq) technology […]
Genes, Vol. 6, Pages 1315-1329: Molecular Modeling of Myrosinase from Brassica oleracea: A Structural Investigation of Sinigrin Interaction
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Myrosinase, which is present in cruciferous plant species, plays an important role in the hydrolysis of glycosides such as glucosinolates and is involved in plant defense. Brassicaceae myrosinases are diverse although they share common ancestry, and structural knowledge about myrosinases from cabbage (Brassica oleracea) was needed. To address this, we constructed a three-dimensional model structure […]
Association between HMGB1 and COPD: A Systematic Review
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
HMGB1 is an alarmin, a protein that warns and activates inflammation. Chronic obstructive pulmonary disease (COPD) is characterised by a progressive airflow obstruction and airway inflammation. Current anti-inflammatory therapies are poorly effective in maintaining lung function and symptoms of COPD. This underlines the need for finding new molecular targets involved in disease pathogenesis in order […]
Improving Stem and Progenitor Cell Therapeutics
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RA2cdU via IFTTT
Allergy to Prolene Sutures in a Dural Graft for Chiari Decompression
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Allergy to Prolene suture is exceedingly rare with only 5 cases reported in the literature. There have been no such cases associated with neurosurgical procedures. Diagnosis is nearly always delayed in spite of persistent symptomatology. A 27-year-old girl with suspected Ehlers-Danlos, connective tissue disorder, underwent posterior fossa decompression for Chiari Type 1 malformation. One year […]
Laparoscopic Excision of Large Intra-Abdominal Cysts in Children: Needle Hitch Technique
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Laparoscopic surgery has both diagnostic and therapeutic advantages in the management of intra-abdominal cysts in children. Large cysts in small children pose technical challenges during laparoscopic surgery, requiring multiple incisions and advanced laparoscopic skills. This paper describes a novel laparoscopic technique using minimal manipulation for both aspiration and excision of the cyst. This simple, safe, […]
Thyroid Autoantibodies in the Cerebrospinal Fluid of Subjects with and without Thyroid Disease: Implications for Hashimoto’s Encephalopathy
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Introduction. Plasma antithyroid peroxidase (anti-TPO) and anti-thyroglobulin antibodies (anti-Tg) are widely used in the diagnosis of autoimmune thyroiditis. No research has compared anti-TPO and anti-Tg both in plasma and cerebrospinal fluid (CSF) of healthy individuals vis-à-vis patients with thyroid disease. Methods. We measured anti-TPO and anti-Tg antibodies in plasma and CSF in nine subjects (mean […]
Risk factors for neuroendocrine neoplasms
Risk factors for neuroendocrine neoplasms: a systematic review and meta-analysis: Background Neuroendocrine neoplasms (NENs) are rare cancers mainly of lung and digestive tract. Little is known on risk factors. The aim of this work is to define the risk factors for NEN development by extensive review and meta-analysis of published data. Methods The search was conducted on Medline, Scopus, and Web of Science following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The Newcastle–Ottawa scale was used for study quality. Meta-analyses were conducted by primary...περισσότερα »
Comprehensive serum cytokine analysis identifies IL-1RA and soluble IL-2R{alpha} as predictors of event-free survival in T-cell lymphoma
Comprehensive serum cytokine analysis identifies IL-1RA and soluble IL-2R{alpha} as predictors of event-free survival in T-cell lymphoma: Background T-cell malignancies are heterogeneous in their clinical presentation and pathology, and have a poor prognosis. New biomarkers are needed to predict prognosis and to provide insights into signal pathways used by these cells. The goal of this study was to evaluate pretreatment serum cytokines in patients with newly diagnosed T-cell neoplasms and correlate with clinical outcome. Patients and methods We evaluated 30 cytokines in pretreatm...περισσότερα »
Single-dose fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting
Single-dose fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting associated with moderately emetogenic chemotherapy: results of a randomized, double-blind phase III trial: Background To establish the role of antiemetic therapy with neurokinin-1 (NK1) receptor antagonists (RAs) in nonanthracycline and cyclophosphamide (AC)-based moderately emetogenic chemotherapy (MEC) regimens, this study evaluated single-dose intravenous (i.v.) fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting (CINV) associated with non-AC MEC. Patients and method... περισσότερα »
EGFR mutation-positive adenocarcinoma that transformed into squamous cell carcinoma
Two cases of EGFR mutation-positive lung adenocarcinoma that transformed into squamous cell carcinoma: successful treatment of one case with rociletinib: 1. K. Haratani1, 2. H. Hayashi1,*, 3. S. Watanabe1, 4. H. Kaneda1,2, 5. T. Yoshida1, 6. M. Takeda1, 7. T. Shimizu1 and 8. K. Nakagawa1 -Author Affiliations 1. 1Department of Medical Oncology, Kinki University Faculty of Medicine , Osaka-Sayama 2. 2Department of Medical Oncology, Kishiwada City Hospital, Kishiwada, Japan 1. ↵*(E-mail: hayashi_h@dotd.med.kindai.ac.jp) Epidermal grow... περισσότερα »
Enzalutamide and sleep apnea: an emerging central nervous system side-effect?
Enzalutamide and sleep apnea: an emerging central nervous system side-effect? 1. F. Labrize1, 2. L. Cany2, 3. C. Massard3, 4. Y. Loriot3, 5. P. Sargos4, 6. M. Gross-Goupil1 and 7. G. Roubaud1,* -Author Affiliations 1. 1Department of Medical Oncology, Institut Bergonié, Bordeaux 2. 2Department of Medical Oncology, Clinique Francheville, Périgueux 3. 3Department of Cancer Medicine, Institut Gustave Roussy, University of Paris Sud,Villejuif 4. 4Department of Radiotherapy, Institut Bergonié, Bordeaux, France 1. ↵*(E-mail: g.roubaud@bordeau... περισσότερα »
FP-1039 (GSK3052230), a Novel FGF Ligand Trap, in Patients with Advanced Solid Tumors
A Phase 1, First in Human Study of FP-1039 (GSK3052230), a Novel FGF Ligand Trap, in Patients with Advanced Solid Tumors: FP-1039 is a first-in-class ligand trap designed to enable complete pathway inhibition in FGF pathway-driven cancers. FP-1039 binds to and inhibits FGFs that normally bind FGFR1, but unlike TKIs, it does not block the hormonal FGFs. The preliminary clinical evidence we reported here supports that FP-1039 is well tolerated in patients without evidence of the toxicities seen with other approaches. 1. A. W. Tolcher1, 2. K. P. Papadopoulos1, 3. A. Pa... περισσότερα »
FP-1039 (GSK3052230), a Novel FGF Ligand Trap, in Patients with Advanced Solid Tumors
A Phase 1, First in Human Study of FP-1039 (GSK3052230), a Novel FGF Ligand Trap, in Patients with Advanced Solid Tumors: FP-1039 is a first-in-class ligand trap designed to enable complete pathway inhibition in FGF pathway-driven cancers. FP-1039 binds to and inhibits FGFs that normally bind FGFR1, but unlike TKIs, it does not block the hormonal FGFs. The preliminary clinical evidence we reported here supports that FP-1039 is well tolerated in patients without evidence of the toxicities seen with other approaches. 1. A. W. Tolcher1, 2. K. P. Papadopoulos1, 3. A. Pa... περισσότερα »
Prognostic markers and tumour growth kinetics in melanoma patients progressing on vemurafenib.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Prognostic markers and tumour growth kinetics in melanoma patients progressing on vemurafenib.: The BRAF inhibitor vemurafenib is an effective drug in patients with BRAF mutant metastatic melanoma, but resistance occurs after a median of 6 months. The anti-CTLA4-antibody, ipilimumab, is a standard first-line and second-line treatment option in Europe, with a median time to response […]
HIV identified as leading risk factor for stroke in young African adults
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
HIV infection is the leading risk factor for stroke in young African adults, a new study by the University of Liverpool’s Institute of Infection and Global Health has found. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Ny0kyz via IFTTT
MAP Kinase pathway gene copy alterations in NRAS/BRAF wild-type advanced melanoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
MAP Kinase pathway gene copy alterations in NRAS/BRAF wild-type advanced melanoma: Abstract Recent therapeutic advances have improved melanoma patientś clinical outcome. Novel therapeutics targeting BRAF, NRAS and cKit mutant melanomas are widely used in clinical practice. However therapeutic options in NRASwild-type/BRAFwild-type/cKitwild-type melanoma patients are limited. Our study shows that gene copy numbers of members of […]
Drexel’s brain imaging technology offers new approach for studying Parkinsonian syndromes
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Using a portable device developed at Drexel University, researchers at Albert Einstein College of Medicine have identified differences in brain activation patterns associated with postural… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QF23Ww via IFTTT
PARKIN Inactivation Links Parkinsons Disease to Melanoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
PARKIN Inactivation Links Parkinsons Disease to Melanoma: Background: Melanoma incidence is higher in patients affected by Parkinson’s disease (PD) and vice versa, but the genetic link shared by both diseases is unknown. As PARK2 is both a tumor suppressor gene and frequently mutated in young onset PD, we evaluated the role of PARK2 in melanoma […]
Cytoplasmic expression of maspin predicts unfavourable prognosis in patients with squamous cell carcinoma of the lung
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Abstract Aims Maspin is known to be a tumour suppressor protein and its prognostic significance in patients with several types of cancer including lung squamous cell carcinoma (SCC) has been reported. However, its prognostic impact on lung SCC has been controversial. We explored the prognostic value of maspin expression with particular reference to its subcellular […]
Stereotactic radiosurgery alone for limited brain metastases
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Stereotactic radiosurgery alone for limited brain metastases: are we ready for prime time?: CNS Oncology Ahead of Print. from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1UVWBxq via IFTTT
Keratinocyte cancers and melanoma : Measured body size and height and risk
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
A prospective study of measured body size and height and risk of keratinocyte cancers and melanoma via ScienceDirect Publication: Cancer Epidemiology (open access) Publication date: February 2016 Source:Cancer Epidemiology, Volume 40 Author(s): Petra H. Lahmann, Maria Celia B. Hughes, Gail M. Williams, Adèle C. Green BackgroundThe potential influence of measured body weight and height on […]
Acute toxicity grade 3 and 4 after irradiation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
in children and adolescents: results from the IPPARCA collaboration via International Journal of Radiation Oncology*Biology*Physics Publication date: Available online 19 December 2015 Source:International Journal of Radiation Oncology*Biology*Physics Author(s): Caroline Pixberg, Raphael Koch, Hans-Theodor Eich, Ulla Martinsson, Ingrid Kristensen, Christiane Matuschek, Rolf-Dieter Kortmann, Fabian Pohl, Khaled Elsayad, Hans Christiansen, Normann Willich, Jack Lindh, Diana Steinmann Background […]
Effective local control of advanced soft tissue sarcoma with neoadjuvant chemoradiotherapy and surgery
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
: A single institutional experience via Cancer/Radiothérapie Publication date: Available online 11 December 2015 Source:Cancer/Radiothérapie Author(s): F. Stubbe, A. Agaimy, O. Ott, S. Lettmaier, N. Vassos, R. Croner, W. Hohenberger, R. Fietkau, S. Semrau PurposeThere is a sound theoretical basis but little clinical evidence substantiating the benefits of concurrent chemoradiotherapy with two-drug chemotherapy for locally […]
TP53 mutational status is predictive of pazopanib response in advanced sarcomas
TP53 mutational status is predictive of pazopanib response in advanced sarcomas: The p53-VEGF pathway is critical for the growth and metastases of soft tissue sarcomas. Inhibition of VEGFR is one way to disrupt this pathway and mutations in TP53 may predict response to VEGFR inhibition in metastatic STSs. 1. K. Koehler1, 2. D. Liebner1,2 and 3. J.L. Chen2,1 -Author Affiliations 1. 1Division of Medical Oncology, Department of Internal Medicine, The Ohio State University, Columbus, US 2. 2Division of Bioinformatics, Department of Biomedical Informatics, ... περισσότερα »
Epstein-Barr virus reactivation in extranodal natural killer/T-cell lymphoma
Epstein-Barr virus reactivation in extranodal natural killer/T-cell lymphoma patients: a previously unrecognized serious adverse event in a pilot study with romidepsin: Romidepsin may cause Epstein–Barr virus reactivation in extranodal natural killer/T-cell lymphoma patients. 1. S. J. Kim1, 2. J.H. Kim2, 3. C.S. Ki3, 4. Y.H. Ko4, 5. J.S. Kim5 and 6. W.S. Kim6 -Author Affiliations 1. 1Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, and Department of Health Sciences and ... περισσότερα »
Prognostic value of Tumor-infiltrating lymphocytes in Epstein-Barr virus-associated gastric cancer
Prognostic value of Tumor-infiltrating lymphocytes in Epstein-Barr virus-associated gastric cancer: While several studies have noted the strong prognostic and predictive significance of tumor-infiltrating lymphocytes (TILs) for various human malignancies, their clinical significance and exact cellular characteristics remain unclear in Epstein-Barr virus (EBV)-associated gastric cancer (EBVaGC). The Cancer Genome Atlas Research Network recently provided a comprehensive molecular characterization of 295 gastric cancers using various platforms, and proposed four distinct subtypes, as ...περισσότερα »
The genomic and transcriptomic landscape of anaplastic thyroid cancer: implications for therapy
The genomic and transcriptomic landscape of anaplastic thyroid cancer: implications for therapy: Abstract BackgroundAnaplastic thyroid carcinoma is the most undifferentiated form of thyroid cancer and one of the deadliest of all adult solid malignancies. Here we report the first genomic and transcriptomic profile of anaplastic thyroid cancer including those of several unique cell lines and outline novel potential drivers of malignancy and targets of therapy. MethodsWe describe whole genomic and transcriptomic profiles of 1 primary anaplastic thyroid tumor and 3 authenticated ce...περισσότερα »
Infective endocarditis and cancer in the elderly
Infective endocarditis and cancer in the elderly: AbstractLittle is known about the magnitude of the association between infective endocarditis and cancer, and about the natural history of cancer patients with concomitant diagnosis of infective endocarditis. We used the SEER-Medicare linked database to identify individuals aged 65 years or more diagnosed with colorectal, lung, breast, or prostate cancer, and without any cancer diagnosis (5 % random Medicare sample from SEER areas) between 1992 and 2009. We identified infective endocarditis from the ICD-9 diagnosis of each admission...περισσότερα »
Rapid thyroid nodule growth is not a marker for well-differentiated thyroid cancer
Rapid thyroid nodule growth is not a marker for well-differentiated thyroid cancer: Abstract BackgroundRapid growth of thyroid nodules is described as being associated with thyroid cancer. The objective of the study was to determine how the growth rate of thyroid nodules during follow-up is associated with the risk of thyroid cancer. MethodsRetrospective analysis of patients undergoing thyroid surgery for nodular disease and a repetitive preoperative ultrasound work-up of at least 6 months was done. Nodule growth was considered relevant when a volume increase >49 % was detecte... περισσότερα »
Identification of a small molecule that downregulates MITF expression and mediates antimelanoma activity in vitro.
Identification of a small molecule that downregulates MITF expression and mediates antimelanoma activity in vitro.: Melanoma is a type of cancer arising from the melanocytes, which are the cells that make up the pigment melanin and are derived from the neural crest. There is no particularly effective therapy once the disease is metastatic, highlighting the need for discovery of novel potent agents. In this investigation, we adopted a zebrafish embryonic pigmentation model to identify antimelanoma agents by screening an in-house small molecule library. With this assay, we found that ... περισσότερα »
Prognostic markers and tumour growth kinetics in melanoma patients progressing on vemurafenib.
Prognostic markers and tumour growth kinetics in melanoma patients progressing on vemurafenib.: The BRAF inhibitor vemurafenib is an effective drug in patients with BRAF mutant metastatic melanoma, but resistance occurs after a median of 6 months. The anti-CTLA4-antibody, ipilimumab, is a standard first-line and second-line treatment option in Europe, with a median time to response of 2-3 months, but some patients show rapid clinical deterioration before that. The aim of this analysis was to identify prognostic markers for survival after failure of vemurafenib treatment to identify ... περισσότερα »
Rituximab and risk of second primary malignancies in patients with non-Hodgkin lymphoma: a systematic review and meta-analysis
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Rituximab and risk of second primary malignancies in patients with non-Hodgkin lymphoma: a systematic review and meta-analysis: Rituximab (R) has drastically improved outcome in B-cell non-Hodgkin lymphoma increasing the number of long-term survivors. We performed a meta-analysis including 4621 patients from randomized trials to evaluate the impact of R on second primary malignancies (SPM) risk. At a median follow-up of 73 months, no increased risk of SPM was observed (OR= 0.88; 95%CI: 0.66-1.19). No subgroup based on clinical characteristics or R administration demonstrated a high...περισσότερα »
Primary Invasive Squamous Cell Carcinoma of the Nipple
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Squamous cell carcinoma is one of the most common cutaneous cancers; however, primary squamous cell carcinoma of the nipple is extremely rare. Among the few reported cases, the majority have occurred in older women with rare cases seen in younger women and male patients. Our patient presented with an exophytic mass of the right nipple while pregnant. A superficial biopsy was reviewed at an outside institution and then at our institution and diagnosed as squamous papilloma and then as hyperkeratosis of the nipple, respectively. The subsequent excisional biopsy revealed multiple nes...περισσότερα »
MAP Kinase pathway gene copy alterations in NRAS/BRAF wild-type advanced melanoma
MAP Kinase pathway gene copy alterations in NRAS/BRAF wild-type advanced melanoma: Abstract Recent therapeutic advances have improved melanoma patientś clinical outcome. Novel therapeutics targeting *BRAF, NRAS* and *cKit* mutant melanomas are widely used in clinical practice. However therapeutic options in *NRAS*wild-type/*BRAF*wild-type/*cKit*wild-type melanoma patients are limited. Our study shows that gene copy numbers of members of the MAPK signaling pathway vary in different melanoma subgroups. *NRAS*wild-type/ *BRAF*wild-type melanoma metastases are characterized by significa... περισσότερα »
PARKIN Inactivation Links Parkinsons Disease to Melanoma
PARKIN Inactivation Links Parkinsons Disease to Melanoma: Background: Melanoma incidence is higher in patients affected by Parkinson’s disease (PD) and vice versa, but the genetic link shared by both diseases is unknown. As *PARK2* is both a tumor suppressor gene and frequently mutated in young onset PD, we evaluated the role of *PARK2* in melanoma predisposition and progression. Methods: An in-depth *PARK2* gene dosage analysis and sequencing was performed on 512 French case patients and 562 healthy control patients, as well as sporadic tumors and melanoma cell lines. The frequenc... περισσότερα »
Stereotactic radiosurgery alone for limited brain metastases
Stereotactic radiosurgery alone for limited brain metastases: are we ready for prime time?: CNS Oncology Ahead of Print. [image: Free first page]
Keratinocyte cancers and melanoma : Measured body size and height and risk
A prospective study of measured body size and height and risk of keratinocyte cancers and melanoma via ScienceDirect Publication: Cancer Epidemiology (open access) Publication date: February 2016 *Source:*Cancer Epidemiology, Volume 40 Author(s): Petra H. Lahmann, Maria Celia B. Hughes, Gail M. Williams, Adèle C. Green BackgroundThe potential influence of measured body weight and height on keratinocyte skin cancer risk has scarcely been studied. Some evidence indicates melanoma risk increases as self-reported height increases, but an association with body mass index (BMI) is less certa... περισσότερα »
Acute toxicity grade 3 and 4 after irradiation
in children and adolescents: results from the IPPARCA collaboration via International Journal of Radiation Oncology*Biology*Physics Publication date: Available online 19 December 2015 *Source:*International Journal of Radiation Oncology*Biology*Physics Author(s): Caroline Pixberg, Raphael Koch, Hans-Theodor Eich, Ulla Martinsson, Ingrid Kristensen, Christiane Matuschek, Rolf-Dieter Kortmann, Fabian Pohl, Khaled Elsayad, Hans Christiansen, Normann Willich, Jack Lindh, Diana Steinmann Background and PurposeIn the context of oncologic therapy for children, radiotherapy is frequently indi... περισσότερα »
Effective local control of advanced soft tissue sarcoma with neoadjuvant chemoradiotherapy and surgery
: A single institutional experience via Cancer/Radiothérapie Publication date: Available online 11 December 2015 *Source:*Cancer/Radiothérapie Author(s): F. Stubbe, A. Agaimy, O. Ott, S. Lettmaier, N. Vassos, R. Croner, W. Hohenberger, R. Fietkau, S. Semrau PurposeThere is a sound theoretical basis but little clinical evidence substantiating the benefits of concurrent chemoradiotherapy with two-drug chemotherapy for locally advanced soft tissue sarcomas. Our five-year data on the feasibility and effectiveness of neoadjuvant chemoradiotherapy with systemically effective doses of adriamy... περισσότερα »
Transcriptomics based hypoxia signatures in head- and neck squamous cell carcinoma
Comparative analysis of transcriptomics based hypoxia signatures in head- and neck squamous cell carcinoma: [image: gr1.sml] Hypoxia renders tumors resistant to radiotherapy. However, the paucity of sensitive and reliable methods for detection of tumor hypoxia limits the translation of novel therapy strategies targeting this well-known resistance factor. We sought to investigate the ability of three previously discovered transcriptomics based hypoxia signatures to identify hypoxic tumors and consequently discriminate between patients with poor- vs. good prognosis.
EGFR monoclonal antibodies in locally advanced head and neck squamous cell carcinoma
: What is their current role? via Critical Reviews in Oncology/Hematology (open access) Publication date: Available online 19 December 2015 *Source:*Critical Reviews in Oncology/Hematology Author(s): Mohamed Alorabi, Nicole A Shonka, Apar Kishor Ganti Treatment options for locally advanced squamous cell carcinoma of the head and neck (SCCHN) include either surgical resection followed by radiation or chemoradiation, or definitive chemoradiation for which single-agent cisplatin is the best studied and established. The increasing understanding of the molecular biology of SCCHN has led to a... περισσότερα »
Antibiotic drug tigecycline reduces neuroblastoma cells proliferation
Antibiotic drug tigecycline reduces neuroblastoma cells proliferation by inhibiting Akt activation in vitro and in vivo: AbstractAs the first member of glycylcycline bacteriostatic agents, tigecycline is approved as a novel expanded-spectrum antibiotic, which is clinically available. However, accumulating evidence indicated that tigecycline was provided with the potential application in cancer therapy. In this paper, tigecycline was shown to exert an anti-proliferative effect on neuroblastoma cell lines. Furthermore, it was found that tigecycline induced G1-phase cell cycle arrest ... περισσότερα »
MicroRNA-663 suppresses cell invasion and migration by targeting transforming growth factor beta 1 in papillary thyroid carcinoma
MicroRNA-663 suppresses cell invasion and migration by targeting transforming growth factor beta 1 in papillary thyroid carcinoma: AbstractMicroRNA-663 (miR-663) has been detected in a large variety of tumor types; however, it still holds both tumor suppressive and oncogenic roles in different tumor types. The miRNA-CHIP microarray assay revealed downregulation of miR-663 in papillary thyroid carcinoma (PTC); however, the effect of miR-663 on PTC cell invasion and migration remains unknown. Accordingly, this study aimed to investigate the potential involvement of miR-663 in PTC. In... περισσότερα »
PTEN and p16 genes as epigenetic biomarkers in oral squamous cell carcinoma (OSCC): a study on south Indian population
PTEN and p16 genes as epigenetic biomarkers in oral squamous cell carcinoma (OSCC): a study on south Indian population: AbstractPhosphatase and tensin homolog (PTEN) and p16INK4a (p16) genes are tumor suppressor genes, associated with epigenetic alterations. PTEN and p16 promoter hypermethylation is a major epigenetic silencing mechanism leading to cancer. The cooperation between PTEN and p16 in pathogenesis of cancers suggest that their combination might be considered as potential molecular marker for specific subgroups of patients. Hence, the present study aimed to investigate wh... περισσότερα »
ANG1/2-Tie2 inhibitor trebaninib (AMG386) and temsirolimus in advanced solid tumors (PJC008/NCI♯9041)
A phase I trial of ANG1/2-Tie2 inhibitor trebaninib (AMG386) and temsirolimus in advanced solid tumors (PJC008/NCI♯9041): Summary*Background* There is crosstalk between the ANG-Tie2 and the PI3K/Akt/mTOR pathways. Combined ANG1/2 and mTOR blockade may have additive anti-cancer activity. The combination of trebananib, an inhibitor of ANG1/2-Tie2 interaction, with temsirolimus was evaluated in patients with advanced solid tumors to determine tolerability, maximum tolerated dose (MTD), and preliminary antitumor activity. *Methods* Patients were enrolled using 3 + 3 design, and were gi...περισσότερα »
Communication and US-Somali Immigrant Human Papillomavirus (HPV) Vaccine Decision-Making
Communication and US-Somali Immigrant Human Papillomavirus (HPV) Vaccine Decision-Making: AbstractThe current study uses a multiple goal theoretical perspective to explore how Somali immigrant families living in Ohio, USA, make decisions regarding whether to vaccinate their children against human papillomavirus (HPV)—a leading cause of cervical cancer. A focus was placed on the communication goals of parents in HPV vaccine discussions with their child and health care provider. Semi-structured interviews were audiotaped, transcribed, and analyzed using a grounded theory approach. Ke... περισσότερα »
Endonasal Microdebrider Assisted Excision of Congenital Intranasal Nasolacrimal Duct Cyst or Inferior Mucocoele
Endonasal Microdebrider Assisted Excision of Congenital Intranasal Nasolacrimal Duct Cyst or Inferior Mucocoele: Abstract ObjectiveCongenital intranasal nasolacrimal duct (NLD) cyst is a rare clinical entity in the newborn whilst inferior mucocoeles are more common. We reviewed our case series of the management of patients presenting with congenital intranasal NLD cysts and inferior mucocoeles treated using powered instrumentation under endoscopic guidance. MethodsA retrospective review identified three patients, between 2010 and 2013, who have had microdebrider assisted endosc...περισσότερα »
Crystal storing histiocytosis clinically mimicking metastatic carcinoma
Crystal storing histiocytosis clinically mimicking metastatic carcinoma: Report of a case and reviews of literature: Abstract Background Crystal storing histiocytosis (CSH) is a rare disorder characterized by accumulation of histiocytes containing crystalline material inclusions. This entity can be misdiagnosed as infection or tumor. We present a case of idiopathic CSH mimicking metastatic squamous cell carcinoma in a cervical lymph node and review of literature regarding this rare entity. Methods and Results The patient was a 70-year-old man with a medical history of squamous cell ... περισσότερα »
Improving the rate of negative margins after surgery for oral cavity squamous cell carcinoma: A prospective randomized controlled study
Improving the rate of negative margins after surgery for oral cavity squamous cell carcinoma: A prospective randomized controlled study: Abstract Background A positive margin is among the most significant factors that affects the outcome in head and neck squamous cell carcinoma (SCC). The purpose of this study was to compare the negative margin rates between 2 methods of intraoperative margin assessment in patients with oral cavity SCC. Methods A prospective, randomized controlled trial comparing 2 methods of intraoperative margin assessment: specimen-driven margins and patient-driv... περισσότερα »
Parathyroid carcinoma with contralateral subcutaneous and breast recurrences: A rare presentation
Parathyroid carcinoma with contralateral subcutaneous and breast recurrences: A rare presentation: Abstract Background Parathyroid carcinoma is extremely rare. Correct preoperative and even histopathological diagnosis may be difficult owing to the deceptively bland cytoarchitectural features, especially when presenting with localized disease. Recurrence/metastases developing years later then make the malignant nature obvious. Methods and Results We present here an unusual case of a 32-year-old patient with carcinoma of the left upper parathyroid gland, initially diagnosed as parathy... περισσότερα »
Relationship between Clinical and Immunological Features of Thyroid Autoimmunity and Ophthalmopathy during Pregnancy
Relationship between Clinical and Immunological Features of Thyroid Autoimmunity and Ophthalmopathy during Pregnancy: Problem. Clinical features of Graves’ hyperthyroidism (GH) generally improve during pregnancy and rebound in the postpartum period. It is unclear whether the ophthalmopathy that is associated with GH and, less often, Hashimoto’s thyroiditis (HT) changes in parallel with the thyroid associated antibody reactions and clinical features or runs a different course. Method of Study. We retrospectively studied 19 patients with autoimmune thyroid disease over 22 pregnancies:...περισσότερα »
Iterated intracochlear reflection shapes the envelopes of basilar-membrane click responses
Iterated intracochlear reflection shapes the envelopes of basilar-membrane click responses: Multiple internal reflection of cochlear traveling waves has been argued to provide a plausible explanation for the waxing and waning and other temporal structures often exhibited by the envelopes of basilar-membrane (BM) and auditory-nerve responses to acoustic clicks. However, a recent theoretical analysis of a BM click response measured in chinchilla concludes that the waveform cannot have arisen via any equal, repetitive process, such as iterated intracochlear reflection [Wit and Bell (2... περισσότερα »
Chirp-Evoked Auditory Brainstem Response in Children
Chirp-Evoked Auditory Brainstem Response in Children: A Review: Purpose The aim of this study was to assess the use of the chirp stimulus to record auditory brainstem responses in the pediatric population via a traditional review. Method An electronic search of the literature and a hand search of the literature were conducted. Studies that utilized chirp stimuli within the pediatric population that met all of the inclusion criteria were included in this review. Qualitative synthesis and interpretation of the data were completed. Results Seven studies that met the inclusion crite... περισσότερα »
Salivary Cortisol Profiles of Children with Hearing Loss.
Salivary Cortisol Profiles of Children with Hearing Loss.: Objectives: It has long been speculated that effortful listening places children with hearing loss at risk for fatigue. School-age children with hearing loss experiencing cumulative stress and listening fatigue on a daily basis might undergo dysregulation of hypothalamic-pituitary-adrenal (HPA) axis activity resulting in elevated or flattened cortisol profiles. The purpose of this study was to examine whether school-age children with hearing loss show different diurnal salivary cortisol patterns than children with normal hea... περισσότερα »
Wideband reflectance tympanometry
Longitudinal development of wideband reflectance tympanometry in normal and at-risk infants via Hearing Research Publication date: Available online 19 December 2015 *Source:*Hearing Research Author(s): Lisa L. Hunter, Douglas H. Keefe, M. Patrick Feeney, Denis F. Fitzpatrick, Li Lin PurposeThe goals of this study were to measure normal characteristics of ambient and tympanometric wideband acoustic reflectance, which was parameterized by absorbance and group delay, in newborns cared for in well-baby and Neonatal Intensive Care Unit (NICU) nurseries, and to characterize the normal devel... περισσότερα »
Functional-structural reorganisation of the neuronal network for auditory perception
in subjects with unilateral hearing loss: Review of neuroimaging studies via Hearing Research Publication date: Available online 19 December 2015 *Source:*Hearing Research Author(s): Peder O.Laugen Heggdal, Jonas Brännström, Hans Jørgen Aarstad, Flemming S. Vassbotn, Karsten Specht ObjectiveThis paper aims to provide a review of studies using neuroimaging to measure functional-structural reorganisation of the neuronal network for auditory perception after unilateral hearing loss.DesignA literature search was performed in PubMed. Search criterions were peer reviewed original research p...περισσότερα »
Preliteracy Speech Sound Production Skill and Linguistic Characteristics of Grade 3 Spellings: A Study Using the Templin Archive
Preliteracy Speech Sound Production Skill and Linguistic Characteristics of Grade 3 Spellings: A Study Using the Templin Archive: Purpose This archival investigation examined the relationship between preliteracy speech sound production skill (SSPS) and spelling in Grade 3 using a dataset in which children's receptive vocabulary was generally within normal limits, [speech therapy was not provided until Grade 2, and phonological awareness instruction was discouraged at the time data were collected. Method Participants (N = 250), selected from the Templin Archive (Templin, 2004), va... περισσότερα »
The Influence of Phonotactic Probability on Nonword Repetition and Fast Mapping in 3-Year-Olds With a History of Expressive Language Delay
The Influence of Phonotactic Probability on Nonword Repetition and Fast Mapping in 3-Year-Olds With a History of Expressive Language Delay: Purpose The purpose of this study was to examine the influence of phonotactic probability on sublexical (phonological) and lexical representations in 3-year-olds who had a history of being late talkers in comparison with their peers with typical language development. Method Ten 3-year-olds who were late talkers and 10 age-matched typically developing controls completed nonword repetition and fast mapping tasks; stimuli for both experimental pr...περισσότερα »
Do tissue spears used to clear ear canal pus improve hearing? A case series study of hearing in remote Australian Aboriginal children with chronic suppurative otitis media before and after dry mopping with tissue spears
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 34 δευτερόλεπτα
Research Articles K Sparrow, L Sanchez, D Turner, P MacFarlane, A S Carney The Journal of Laryngology Otology, FirstView Article(s), 5 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1NGYAAI via IFTTT
Short-term weight gain after adenotonsillectomy in children with obstructive sleep apnoea: systematic review
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 34 δευτερόλεπτα
Review Articles M Van, I Khan, S S M Hussain The Journal of Laryngology Otology, FirstView Article(s), 5 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mvX6Tm via IFTTT
Risk factors for post-thyroidectomy haematoma
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 34 δευτερόλεπτα
Research Articles M Perera, L Anabell, D Page, T Harding, N Gnaneswaran, S Chan The Journal of Laryngology Otology, FirstView Article(s), 6 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1NGYA3O via IFTTT
Inside Front Cover (Editorial Board)
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 34 δευτερόλεπτα
Publication date: 15 February 2016 Source:Agricultural and Forest Meteorology, Volume 217 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22kb8Ib via IFTTT
New model for vascular and tumor research
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 34 δευτερόλεπτα
VOGIM cell culture technique allows tumor growth to be observed. Two characteristic features of malignant tumours are that they form massive blood vessels and bypass the immune system. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Mr1M1x via IFTTT
HIV identified as leading risk factor for stroke in young African adults
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 34 δευτερόλεπτα
HIV infection is the leading risk factor for stroke in young African adults, a new study by the University of Liverpool’s Institute of Infection and Global Health has found. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Ny0kyz via IFTTT
Drexel’s brain imaging technology offers new approach for studying Parkinsonian syndromes
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 34 δευτερόλεπτα
Using a portable device developed at Drexel University, researchers at Albert Einstein College of Medicine have identified differences in brain activation patterns associated with postural… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QF23Ww via IFTTT
Inside Front Cover (Editorial Board)
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 34 δευτερόλεπτα
Publication date: 15 February 2016 Source:Agricultural and Forest Meteorology, Volume 217 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22kb8Ib via IFTTT
New model for vascular and tumor research
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 34 δευτερόλεπτα
VOGIM cell culture technique allows tumor growth to be observed. Two characteristic features of malignant tumours are that they form massive blood vessels and bypass the immune system. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Mr1M1x via IFTTT
HIV identified as leading risk factor for stroke in young African adults
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 34 δευτερόλεπτα
HIV infection is the leading risk factor for stroke in young African adults, a new study by the University of Liverpool’s Institute of Infection and Global Health has found. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Ny0kyz via IFTTT
Reduction in High-Frequency Hearing Aid Gain Can Improve Performance in Patients With Contralateral Cochlear Implant: A Pilot Study
Reduction in High-Frequency Hearing Aid Gain Can Improve Performance in Patients With Contralateral Cochlear Implant: A Pilot Study: Purpose The purpose of this study was to determine whether an alternate fitting strategy, specifically adjustment to gains in a hearing aid (HA), would improve performance in patients who experienced poorer performance in the bimodal condition when the HA was fit to traditional targets. Method This study was a retrospective chart review from a local clinic population seen during a 6-month period. Participants included 6 users of bimodal stimulation. ... περισσότερα »
Family Member Involvement in Hearing Rehabilitation
This Is a Partnership Between All of Us”: Audiologists' Perceptions of Family Member Involvement in Hearing Rehabilitation: Purpose The purpose of the study was to explore the perceptions of audiologists about the role of family members in hearing rehabilitation for older adults with hearing impairment (HI), the influence of family member involvement on outcomes, and factors affecting family members' involvement. Method A qualitative descriptive research study was undertaken. Using a purposeful sampling strategy, 9 audiologists were recruited. Audiologists participated in individu... περισσότερα »
Study finds that more than one-third of patients with metastatic cancer continue to work: https://t.co/VFyCiCuVl0
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 39 δευτερόλεπτα
Study finds that more than one-third of patients with metastatic cancer continue to work: https://t.co/VFyCiCuVl0 from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/678900389496889344 via IFTTT
Do tissue spears used to clear ear canal pus improve hearing? A case series study of hearing in remote Australian Aboriginal children with chronic suppurative otitis media before and after dry mopping with tissue spears
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 39 δευτερόλεπτα
Research Articles K Sparrow, L Sanchez, D Turner, P MacFarlane, A S Carney The Journal of Laryngology Otology, FirstView Article(s), 5 pages Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1NGYAAI via IFTTT
Short-term weight gain after adenotonsillectomy in children with obstructive sleep apnoea: systematic review
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 39 δευτερόλεπτα
Review Articles M Van, I Khan, S S M Hussain The Journal of Laryngology Otology, FirstView Article(s), 5 pages Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1mvX6Tm via IFTTT
Risk factors for post-thyroidectomy haematoma
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 39 δευτερόλεπτα
Research Articles M Perera, L Anabell, D Page, T Harding, N Gnaneswaran, S Chan The Journal of Laryngology Otology, FirstView Article(s), 6 pages Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1NGYA3O via IFTTT
Making sense of ripples in generalized epilepsy
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 39 δευτερόλεπτα
Publication date: Available online 21 December 2015 Source:Clinical Neurophysiology Author(s): N.E.C. van Klink, P.R. Bauer, M. Zijlmans from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1ZkMKni via IFTTT
Cytoplasmic expression of maspin predicts unfavourable prognosis in patients with squamous cell carcinoma of the lung
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 39 δευτερόλεπτα
Abstract Aims Maspin is known to be a tumour suppressor protein and its prognostic significance in patients with several types of cancer including lung squamous cell carcinoma (SCC) has been reported. However, its prognostic impact on lung SCC has been controversial. We explored the prognostic value of maspin expression with particular reference to its subcellular […]
Infezioni croniche da Hpv: accordo fra Janssen e Bavarian Nordic – www.aboutpharma.com
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 39 δευτερόλεπτα
Infezioni croniche da Hpv: accordo fra Janssen e Bavarian Nordic http://www.aboutpharma.com L’infezione da HPV è la principale responsabile del cancro della cervice uterina e di alcuni tumori della testa e del collo, oltre che di diverse malattie oncologiche rare. Con oltre 300 milioni di nuovi casi riscontrati ogni anno, sia in soggetti di … from […]
More patients with lung cancer could benefit from immunotherapy, study shows
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 39 δευτερόλεπτα
More patients with advanced non-small-cell lung cancer (NSCLC) could benefit from pembrolizumab, says Professor Roy Herbst, Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven, presenting promising results from the… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1ZkIKDr via IFTTT
Afatinib a better choice for EGFR-mutated lung cancer in first-line
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 39 δευτερόλεπτα
Patients with EGFR-activating mutations in advanced lung cancer seem to benefit more from afatinib than gefitinib as first-line treatment, researchers report at the first ESMO Asia 2015 Congress in Singapore. In the global, randomised, open-label Phase… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1IjHLyZ via IFTTT
Addition of tumour-treating fields to temozolomide improves progression free survival in glioblastoma
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 39 δευτερόλεπτα
by ecancer reporter Clare Sansom Glioblastoma, which is also known as grade IV astrosarcoma, is the most common and the most deadly form of brain tumour. About 20% of all tumours that form inside the skull are glioblastomas, and the median survival with… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1ZkIEeM via IFTTT
HBV-specific and global T-cell dysfunction in chronic hepatitis B
Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1TceNSf via IFTTT
Sorafenib suppresses the epithelial-mesenchymal transition of hepatocellular carcinoma cells after insufficient radiofrequency ablation
BMC Cancer from #Medicine via ola Kala on Inoreader http://ift.tt/1S4uTPj via IFTTT
Systematic review with meta-analysis: the diagnostic accuracy of transient elastography for the staging of liver fibrosis in patients with chronic hepatitis B
Alimentary Pharmacology and Therapeutics from #Medicine via ola Kala on Inoreader http://ift.tt/1TceNBM via IFTTT
Potential coeliac disease markers and autoimmunity in olmesartan induced enteropathy: A population-based study
Digestive and Liver Diseases from #Medicine via ola Kala on Inoreader http://ift.tt/1S4uTil via IFTTT
A 12-week treatment with boceprevir, peginterferon and ribavirin for acute hepatitis C in HIV infected patients
Journal of Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1TceM0u via IFTTT
The Comparison of WHOQOL-BREF with Disease Specific Heath Related Quality of Life Questionnaire in Irritable Bowel Syndrome
Acta Medica Iranica from #Medicine via ola Kala on Inoreader http://ift.tt/1TceLKb via IFTTT
Systemic and intestinal levels of factor XIII-A: the impact of inflammation on expression in macrophage subtypes
Journal of Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1S4uSLw via IFTTT
Facial flushing response to alcohol and the risk of esophageal squamous cell carcinoma: A comprehensive systematic review and meta-analysis
Cancer Epidemiology from #Medicine via ola Kala on Inoreader http://ift.tt/1TceLK1 via IFTTT
Quantitative detection and genotyping of Helicobacter pylori from stool using droplet digital PCR reveals variation in bacterial loads that correlates with cagA virulence gene carriage
Helicobacter from #Medicine via ola Kala on Inoreader http://ift.tt/1TceLtJ via IFTTT
Percutaneous real-time sonoelastography as a non-invasive tool for the characterization of solid focal liver lesions: A prospective study
Digestive and Liver Diseases from #Medicine via ola Kala on Inoreader http://ift.tt/1TceN4L via IFTTT
Cytoplasmic expression of maspin predicts unfavourable prognosis in patients with squamous cell carcinoma of the lung
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 48 δευτερόλεπτα
Abstract Aims Maspin is known to be a tumour suppressor protein and its prognostic significance in patients with several types of cancer including lung squamous cell carcinoma (SCC) has been reported. However, its prognostic impact on lung SCC has been controversial. We explored the prognostic value of maspin expression with particular reference to its subcellular […]
Rehabilitation Procedures in the Management of Parkinson’s Disease
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TZuQD7 via IFTTT
Primary Invasive Squamous Cell Carcinoma of the Nipple
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
Squamous cell carcinoma is one of the most common cutaneous cancers; however, primary squamous cell carcinoma of the nipple is extremely rare. Among the few reported cases, the majority have occurred in older women with rare cases seen in younger women and male patients. Our patient presented with an exophytic mass of the right nipple […]
How to Control Component Ratio of Conducting Polymer Blend for Organic Photovoltaic Devices by Annealing
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
There are various conducting polymer blends which are used as hole transporting layers (HTL) in organic photovoltaic devices (OPV). The electrical performance of these conducting polymer blends depends crucially on its surface compositions and morphology. In this paper, we studied poly(3,4-ethylenedioxythiophene)-poly(styrenesulfonate) or PEDOT:PSS as an example of the HTL conducting polymer blends used in OPV. […]
Translocation (6;15)(q12;q15): A Novel Mutation in a Patient with Therapy-Related Myelodysplastic Syndrome
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
Most myelodysplastic syndromes (MDS) present with loss or gain of chromosomal material and less commonly show translocations as a sole abnormality. In addition, certain translocations are more commonly seen in MDS than others, but to our knowledge, the presence of t(6;15) has not been reported in MDS, specifically therapy-related MDS (t-MDS) cases. Patients with t-MDS, […]
Innovative Pharmacological/Therapeutic Approaches against Hepatic Ischemia/Reperfusion Injury
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1O3in13 via IFTTT
Infezioni croniche da Hpv: accordo fra Janssen e Bavarian Nordic – www.aboutpharma.com
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
Infezioni croniche da Hpv: accordo fra Janssen e Bavarian Nordic http://www.aboutpharma.com L’infezione da HPV è la principale responsabile del cancro della cervice uterina e di alcuni tumori della testa e del collo, oltre che di diverse malattie oncologiche rare. Con oltre 300 milioni di nuovi casi riscontrati ogni anno, sia in soggetti di … from […]
More patients with lung cancer could benefit from immunotherapy, study shows
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
More patients with advanced non-small-cell lung cancer (NSCLC) could benefit from pembrolizumab, says Professor Roy Herbst, Chief of Medical Oncology, Yale Cancer Center and Smilow Cancer Hospital at Yale-New Haven, presenting promising results from the… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZkIKDr via IFTTT
Afatinib a better choice for EGFR-mutated lung cancer in first-line
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
Patients with EGFR-activating mutations in advanced lung cancer seem to benefit more from afatinib than gefitinib as first-line treatment, researchers report at the first ESMO Asia 2015 Congress in Singapore. In the global, randomised, open-label Phase… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1IjHLyZ via IFTTT
Addition of tumour-treating fields to temozolomide improves progression free survival in glioblastoma
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
by ecancer reporter Clare Sansom Glioblastoma, which is also known as grade IV astrosarcoma, is the most common and the most deadly form of brain tumour. About 20% of all tumours that form inside the skull are glioblastomas, and the median survival with… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZkIEeM via IFTTT
Dermoscopic clues to differentiate facial lentigo maligna from pigmented actinic keratosis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
Summary Background The limitations of dermoscopy to accurately differentiate between pigmented lentigo maligna (LM) and pigmented actinic keratosis (PAK) might be related to the fact that most studies have focused on pigmented criteria only, without considering additional recognizable features. Objective To investigate the diagnostic accuracy of established dermoscopic criteria for pigmented LM and PAK, but […]
Response to comment of Taher Rajaee and Salar Khani on “Artificial neural network modelling of biological oxygen demand in rivers at the national level with input selection based on Monte Carlo simulations” [Šiljić et al., Environ Sci Pollut Res (2015) 22: 4230-4241]
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1UUoGFj via IFTTT
Mercury, lead, and cadmium in tissues of the Caspian Pond Turtle ( Mauremys caspica ) from the southern basin of Caspian Sea
Abstract Concentrations of cadmium, lead, and mercury were measured in different tissues (liver, muscle, and shell) of 60 Caspian Pond Turtles collected from Tajan and Shiroud Rivers, southern basin of the Caspian Sea. Based on the results, different tissues showed different capacities for accumulating trace elements. The general trend of metals accumulation was: liver > shell > muscle. Results also showed that accumulation of these elements was not significantly different between sex and river in turtles (*p* > 0.05). Based on the results, Hg and Pb concentrations recorded in the ...περισσότερα »
Unexpected effects of sublethal doses of insecticide on the peripheral olfactory response and sexual behavior in a pest insect
Abstract Pesticides have long been used as the main solution to limit agricultural pests, but their widespread use resulted in chronic or diffuse environmental pollutions, development of insect resistances, and biodiversity reduction. The effects of low residual doses of these chemical products on organisms that affect both targeted species (crop pests) but also beneficial insects became a major concern, particularly because low doses of pesticides can induce unexpected positive—also called hormetic—effects on insects, leading to surges in pest population growth at greater rate th... περισσότερα »
An overview of groundwater chemistry studies in Malaysia
Abstract In this paper, numerous studies on groundwater in Malaysia were reviewed with the aim of evaluating past trends and the current status for discerning the sustainability of the water resources in the country. It was found that most of the previous groundwater studies (44 %) focused on the islands and mostly concentrated on qualitative assessment with more emphasis being placed on seawater intrusion studies. This was then followed by inland-based studies, with Selangor state leading the studies which reflected the current water challenges facing the state. From a methodolog... περισσότερα »
Assessing toxic effects of [Omim]Cl and [Omim]BF 4 in zebrafish adults using a biomarker approach
Abstract In the present study, the toxic effects of 1-octyl-3-methylimidazolium chloride ([Omim]Cl) and 1-octyl-3-methylimidazolium tetrafluoroborate ([Omim]BF4) on the zebrafish livers were studied at 0, 5, 10, 20, and 40 mg L−1 on the 7th and 14th days. In addition, the concentrations of [Omim]Cl and [Omim]BF4 in the test water, the acute toxicity of the two ionic liquids (ILs), and the influence of anions on the toxicity of the ILs were evaluated. The acute toxicity test results showed 50 % lethal concentration (LC50) values of 152.3 ± 12.1 mg L−1 for [Omim]Cl and 144.0 ± 11.4 ... περισσότερα »
Allergy to Prolene Sutures in a Dural Graft for Chiari Decompression
Allergy to Prolene suture is exceedingly rare with only 5 cases reported in the literature. There have been no such cases associated with neurosurgical procedures. Diagnosis is nearly always delayed in spite of persistent symptomatology. A 27-year-old girl with suspected Ehlers-Danlos, connective tissue disorder, underwent posterior fossa decompression for Chiari Type 1 malformation. One year later, the patient presented with urticarial rash from the neck to chest. Cerebrospinal fluid and blood testing, magnetic resonance imaging, and intraoperative exploration did not suggest alle... περισσότερα »
Laparoscopic Excision of Large Intra-Abdominal Cysts in Children: Needle Hitch Technique
Laparoscopic surgery has both diagnostic and therapeutic advantages in the management of intra-abdominal cysts in children. Large cysts in small children pose technical challenges during laparoscopic surgery, requiring multiple incisions and advanced laparoscopic skills. This paper describes a novel laparoscopic technique using minimal manipulation for both aspiration and excision of the cyst. This simple, safe, and effective approach was used to achieve traction and facilitate excision of a large intra-abdominal cyst in a neonate and a young child. from Cases via ola Kala on Inor... περισσότερα »
Palliative care conundrums in an Ebola treatment centre
*By Kristian Dye* Dhillon et al. present a case discussing the care of a patient with Ebola, which demonstrates in a micro[image: medical-563427_1280]cosm some of the biggest issues facing healthcare providers in patients with palliative or terminal care needs – albeit in a particular extreme care environment. In the case, the patient is declared palliative and restarted on active management, before being considered palliative once again and passing away. These are issues which perplex physicians in all care settings. 1. When do we consider a patient for palliative care only... περισσότερα »
Synchronous ipsilateral adrenocortical carcinoma and renal cell carcinoma: a rare clinical entity
Synchronous ipsilateral adrenocortical carcinoma (ACC) and renal cell carcinoma (RCC) are rare. Radiological imaging may not in all cases differentiate between the two tumours due to their proximity to each other. We encountered a case where preoperative diagnosis of renal cell carcinoma was made based on the radiological imaging but, following radical nephrectomy, this was found to be synchronous ACC and RCC after histopathological examination. The patient is doing well at 12 months of follow-up, with no clinical or radiological recurrence. from Cases via ola Kala on Inoreader h... περισσότερα »
Floating iris cyst mimicking intravitreal cysticercosis
Description A 12-year-old girl presented with a history of repeated headaches (with no ocular symptoms) for 3 years. There was no history of ocular trauma or surgery. On ocular examination elsewhere, she was diagnosed as having intravitreal cysticercosis after observing a cyst in the left eye and was referred for vitrectomy to a tertiary eye care centre. Her vision was 20/20 in both eyes, with no signs of ocular inflammation. Biomicroscopic examination of the left eye showed a mobile, pigmented, circular cyst in the anterior vitreous, but it was not blocking the pupillary axis (... περισσότερα »
Rare cause of paraparesis: bilateral obturator neuropathy after hysterosalpingectomy
Bilateral obturator nerve injury during pelvic surgery is an infrequent cause of lower limb paraparesis. We report the case of a 45-year-old woman with a large uterine leiomyoma who underwent simple total hysterectomy and bilateral salpingectomy. At 24 h after the surgery, the patient noticed loss of muscle strength when adducting both legs. She had no problem with other movements and no sensory or sphincter abnormalities. Neurological examination confirmed that there was loss of strength only in the adductor muscles, with preserved sensory function and reflexes, suggesting bilater... περισσότερα »
CAEP Residents’ Section: A Unified Voice for Canadian Emergency Medicine Trainees
Editorial Tudor Botnaru, Christina Bova, Jennifer D. Artz, Martin Kuuskne Canadian Journal of Emergency Medicine, FirstView Article(s), 3 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from C via ola Kala on Inoreader http://ift.tt/1m3G1Ae via IFTTT
Cytoplasmic expression of maspin predicts unfavourable prognosis in patients with squamous cell carcinoma of the lung
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Aims Maspin is known to be a tumour suppressor protein and its prognostic significance in patients with several types of cancer including lung squamous cell carcinoma (SCC) has been reported. However, its prognostic impact on lung SCC has been controversial. We explored the prognostic value of maspin expression with particular reference to its subcellular […]
Palliative care conundrums in an Ebola treatment centre
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
By Kristian Dye Dhillon et al. present a case discussing the care of a patient with Ebola, which demonstrates in a microcosm some of the biggest issues facing healthcare providers in patients with palliative or terminal care needs – albeit in a particular extreme care environment. In the case, the patient is declared palliative and […]
Rare cause of paraparesis: bilateral obturator neuropathy after hysterosalpingectomy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Bilateral obturator nerve injury during pelvic surgery is an infrequent cause of lower limb paraparesis. We report the case of a 45-year-old woman with a large uterine leiomyoma who underwent simple total hysterectomy and bilateral salpingectomy. At 24 h after the surgery, the patient noticed loss of muscle strength when adducting both legs. She had […]
Thymoma complicated by deep vein thrombosis of the arm
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Description Our patient was referred urgently with an anterior neck lump. The patient was otherwise well with no history of smoking or radiation exposure. Initial investigation with ultrasound-guided aspiration cytology was suspicious and atypical for thyroid carcinoma. A CT scan demonstrated the neck lump was part of a 64x56x54 mm retrosternal mass infiltrating the superior […]
Two cases of small bowel obstruction secondary to a swallowed potato
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Bowel obstruction due to bezoars (compaction of ingested material within the gastrointestinal tract) is a rare, but well documented occurrence. In this paper, we present two cases of potato-induced small bowel obstruction. Both patients were approximately 50 years old and had cerebral palsy and learning disabilities, respectively. They presented with abdominal pain and bilious vomiting, […]
Combined pulmonary fibrosis and emphysema in hypersensitivity pneumonitis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Combined pulmonary fibrosis and emphysema is a distinct syndrome reported in patients who smoke. A 72-year-old, never-smoking female dairy farmer was referred for progressive dyspnoea on exertion, basal crackles on auscultation, normal spirometry and normal lung volumes but decreased diffusing capacity of the lung for carbon monoxide, centrilobular emphysema in the upper zones of the […]
New research from Harvard, MGH, and Stanford maps brain connections that regulate homeostasis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
New visualization evidence from a magnetic resonance imaging (MRI) study of the human brain demonstrated previously unidentified structural connections between the brainstem and the forebrain. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Tc6KVD via IFTTT
Study: Childhood concussions impair brain function
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
A new study finds that pre-adolescent children who have sustained sports-related concussions have impaired brain function two years following injury. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1kcaZ7j via IFTTT
Cytoplasmic expression of maspin predicts unfavourable prognosis in patients with squamous cell carcinoma of the lung
[image: cover.gif?v=1&s=7528e0ad9d03be2b78c21000] Abstract Aims Maspin is known to be a tumour suppressor protein and its prognostic significance in patients with several types of cancer including lung squamous cell carcinoma (SCC) has been reported. However, its prognostic impact on lung SCC has been controversial. We explored the prognostic value of maspin expression with particular reference to its subcellular localization in patients with lung SCC. Methods and results Paraffin-embedded tissue samples from 101 curatively resected patients with lung SCC were immunohistochemic...περισσότερα »
Osteonecrosis of the Jaw in Patients treated with Denosumab for Metastatic Tumors to the Bone: A Series of Thirteen Patients
Publication date: Available online 20 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Adepitan A. Owosho, Ariel Blanchard, Lauren Levi, Arvin Kadempour, Haley Rosenberg, SaeHee K. Yom, Azeez Farooki, Monica Fornier, Joseph M. Huryn, Cherry L. Estilo This case series describes the course of osteonecrosis of the jaw (ONJ) in thirteen patients with metastatic bone tumors treated solely with denosumab. Patients on denosumab may be more prone to developing ONJ even without a risk/precipitating factor and they may develop ONJ early in their denosumab therapy. The... περισσότερα »
Cytoplasmic expression of maspin predicts unfavourable prognosis in patients with squamous cell carcinoma of the lung
[image: cover.gif?v=1&s=7528e0ad9d03be2b78c21000] Abstract Aims Maspin is known to be a tumour suppressor protein and its prognostic significance in patients with several types of cancer including lung squamous cell carcinoma (SCC) has been reported. However, its prognostic impact on lung SCC has been controversial. We explored the prognostic value of maspin expression with particular reference to its subcellular localization in patients with lung SCC. Methods and results Paraffin-embedded tissue samples from 101 curatively resected patients with lung SCC were immunohistochemic...περισσότερα »
Dermoscopic clues to differentiate facial lentigo maligna from pigmented actinic keratosis
Summary Background The limitations of dermoscopy to accurately differentiate between pigmented lentigo maligna (LM) and pigmented actinic keratosis (PAK) might be related to the fact that most studies have focused on pigmented criteria only, without considering additional recognizable features. Objective To investigate the diagnostic accuracy of established dermoscopic criteria for pigmented LM and PAK, but including in the evaluation features previously associated with non-pigmented facial AK. Methods Retrospectively enrolled cases of histopathologically diagnosed LM, PAK and ...περισσότερα »
The Monte Carlo validation framework for the discriminant partial least squares model extended with variable selection methods applied to authenticity studies of Viagra[registered sign] based on chromatographic impurity profiles
[image: CrossMark.jpg] *Analyst*, 2015, Accepted Manuscript *DOI*: 10.1039/C5AN01656H, Paper B. Krakowska, D. Custers, Eric Deconinck, Michal Daszykowski, The aim of this work was to develop a general framework for the validation of discriminant models based on the Monte Carlo approach that is used in the context of... The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/1UVJkVq via IFTTT
Use of Raman optical tweezers for cell cycle analysis
[image: CrossMark.jpg] *Analyst*, 2015, Accepted Manuscript *DOI*: 10.1039/C5AN00971E, Paper Sunita Ahlawat, Aniket Chowdhury, Abha Uppal, Nitin Kumar, Pradeep Kumar Gupta We report the results of our investigations on the use of Raman optical tweezers for label free analysis of cells in different phases of their cell cycle. The studies performed... The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/1UVJj42 via IFTTT
Protective Effects of Streblus asper Leaf Extract on H2O2-Induced ROS in SK-N-SH Cells and MPTP-Induced Parkinson’s Disease-Like Symptoms in C57BL/6 Mouse
This study investigated the effects of Streblus asper leaf extract (SA) on reactive oxygen species (ROS) in SK-N-SH cell culture and on motor functions and behaviors in MPTP-treated C57BL/6 mice. SK-N-SH cell viability after incubation with SA for 24 h was measured by MTT assay. Intracellular ROS levels of SK-N-SH cells were quantified after pretreatment with SA (0, 200, 600, and 1000 µg/mL) in the presence of H2O2 (300 µM). Male C57BL/6 mice were force-fed with water or 200 mg/kg/day SA for 32 days. Intraperitoneal injection of MPTP was used to induce Parkinson's disease-like sym...περισσότερα »
Interferon gamma effect on immune mediator production in human nerve cells infected by two strains of Toxoplasma gondii
Authors: Nour Mammari, Philippe Vignoles, Mohamad Adnan Halabi, Marie-Laure Dardé and Bertrand Courtioux.<br>Parasite Vol. 22 , page 39<br>Published online: 21/12/2015<br> Keywords: Toxoplasma gondii ; Human nerve cells ; IFN-γ ; Immunity.<img src="http://ift.tt/1IjGgkp" height="1" width="1" alt=""> from #Medicine via ola Kala on Inoreader http://ift.tt/1NGUxV3 via IFTTT
Larval trematode infections in Lymnaea glabra populations living in the Brenne Regional Natural Park, central France
Authors: Daniel Rondelaud, Philippe Vignoles and Gilles Dreyfuss.<br>Parasite Vol. 22 , page 38<br>Published online: 21/12/2015<br> Keywords: Brenne Regional Natural Park ; Cercaria ; Digenean ; Lymnaea glabra ; Lymnaeidae ; Snail.<img src="http://ift.tt/1IjGg44" height="1" width="1" alt=""> from #Medicine via ola Kala on Inoreader http://ift.tt/1NGUxED via IFTTT
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Publication date: January 2016 Source:Cytotherapy, Volume 18, Issue 1 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22k9oyA via IFTTT
Circular dichroism based refractive index sensing using chiral metamaterials
Chem. Commun., 2016, Advance Article DOI: 10.1039/C5CC07742G, Communication Yizhuo He, Keelan Lawrence, Whitney Ingram, Yiping Zhao A new strategy to improve the sensitivity of localized surface plasmon resonance sensors by employing chiral metamaterials is provided. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this …
Global Self-Propelled Sprayer Market 2015 Industry Trends, Growth, Analysis, Demand and Forecast
Global Self-Propelled Sprayer Industry 2015 The Global Self-Propelled Sprayer Industry report gives a comprehensive account of the Global Self-Propelled Sprayer market. Details such as the size, key players, segmentation, SWOT analysis, most influential trends, and business environment of the… from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1UVg9lp via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via …
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Publication date: January 2016 Source:Cytotherapy, Volume 18, Issue 1 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UVwyGw via IFTTT
A rare case of benign cystic peritoneal mesothelioma becoming something worse – read the case report here: https://t.co/mnm1m1ejCO
A rare case of benign cystic peritoneal mesothelioma becoming something worse – read the case report here: https://t.co/mnm1m1ejCO from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/678866657599750146 via IFTTT
Transcriptome profiling of the Pacific oyster Crassostrea gigas by Illumina RNA-seq
Abstract In this study, the whole transcriptome of the Pacific oyster Crassostrea gigas was sequenced using Illumina RNA-seq. De novo assembly was performed with 33,750,764 raw reads using Trinity, which assembled 87,887 contigs. Transdecoder found 41,542 candidate coding contigs which showed homology to other species by BLAST analysis. Functional gene annotation was performed by Gene …
Neuroprotective effects of human umbilical cord–derived mesenchymal stromal cells combined with nimodipine against radiation-induced brain injury through inhibition of apoptosis
Publication date: January 2016 Source:Cytotherapy, Volume 18, Issue 1 Author(s): Gui-Hua Wang, Yang Liu, Xiao-Bing Wu, Ying Lu, Jin Liu, Ya-Ru Qin, Tong Li, Hai-Feng Duan Background aims. Mesenchymal stromal cells (MSCs) possess the ability to repair brain injuries. Additionally, nimodipine is a neuroprotective agent that increases cerebral blood flow and may help with the homing …
Transplantation of tendon-derived stem cells pre-treated with connective tissue growth factor and ascorbic acid in vitro promoted better tendon repair in a patellar tendon window injury rat model
Publication date: January 2016 Source:Cytotherapy, Volume 18, Issue 1 Author(s): Pauline Po Yee Lui, On Tik Wong, Yuk Wa Lee Background aims. Treatment of tendon-derived stem cells (TDSCs) with connective tissue growth factor (CTGF) and ascorbic acid promoted their tenogenic differentiation. We investigated the effects of TDSCs pre-treated with CTGF and ascorbic acid on tendon repair …
Influence of polymorphisms of UDP-glycosyltransferases (UGT) 2B family genes UGT2B15, UGT2B17 and UGT2B28 on the development of prostate cancer in Korean men
Abstract Prostate cancer is known as the fifth most common cancer in Korean male. The etiology of the prostate cancer remains unknown, but age, race, drug, family history, dietary habit and steroid hormone levels have been suggested as causative factors. Among these factors, variations in androgen hormone levels have been suggested as one of risk …
Rare cause of paraparesis: bilateral obturator neuropathy after hysterosalpingectomy
Bilateral obturator nerve injury during pelvic surgery is an infrequent cause of lower limb paraparesis. We report the case of a 45-year-old woman with a large uterine leiomyoma who underwent simple total hysterectomy and bilateral salpingectomy. At 24 h after the surgery, the patient noticed loss of muscle strength when adducting both legs. She had …
Norwood Procedure Performed on a Patient With Trisomy 13.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
We report the case of a neonate weighing 2324 g who was born with severe congenital heart defects. Transthoracic echocardiography revealed the diagnoses of asplenia, single ventricle, aortic stenosis, coarctation of the aorta, hypoplastic aortic arch, and total anomalous pulmonary venous return. She was hemodynamically unstable. Palliative Norwood procedure with right ventricle-pulmonary artery conduit (RV-PA […]
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fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: January 2016 Source:Cytotherapy, Volume 18, Issue 1 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22k9qGB via IFTTT
Table of Contents
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: January 2016 Source:Cytotherapy, Volume 18, Issue 1 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UVwBSR via IFTTT
Sensors, Vol. 15, Pages 32123-32137: Focusing Bistatic FMCW SAR Signal by Range Migration Algorithm Based on Fresnel Approximation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Frequency modulated continuous wave (FMCW) technique has recently been employed by synthetic aperture radar (SAR) to decrease the radar cost and volume. However, the operation range is limited by the direct energy leakage from the transmitting channel to receiving channel due to the operation principle of FMCW technique. Bistatic configuration is an efficient way to […]
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fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: January 2016 Source:Cytotherapy, Volume 18, Issue 1 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22k9oyA via IFTTT
Sensors, Vol. 15, Pages 32152-32167: A TSR Visual Servoing System Based on a Novel Dynamic Template Matching Method
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The so-called Tethered Space Robot (TSR) is a novel active space debris removal system. To solve its problem of non-cooperative target recognition during short-distance rendezvous events, this paper presents a framework for a real-time visual servoing system using non-calibrated monocular-CMOS (Complementary Metal Oxide Semiconductor). When a small template is used for matching with a large […]
Masthead
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: January 2016 Source:Cytotherapy, Volume 18, Issue 1 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UVwyGw via IFTTT
Protective Effects of Streblus asper Leaf Extract on H2O2-Induced ROS in SK-N-SH Cells and MPTP-Induced Parkinson’s Disease-Like Symptoms in C57BL/6 Mouse
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
This study investigated the effects of Streblus asper leaf extract (SA) on reactive oxygen species (ROS) in SK-N-SH cell culture and on motor functions and behaviors in MPTP-treated C57BL/6 mice. SK-N-SH cell viability after incubation with SA for 24 h was measured by MTT assay. Intracellular ROS levels of SK-N-SH cells were quantified after pretreatment with […]
Neuroprotective effects of human umbilical cord–derived mesenchymal stromal cells combined with nimodipine against radiation-induced brain injury through inhibition of apoptosis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: January 2016 Source:Cytotherapy, Volume 18, Issue 1 Author(s): Gui-Hua Wang, Yang Liu, Xiao-Bing Wu, Ying Lu, Jin Liu, Ya-Ru Qin, Tong Li, Hai-Feng Duan Background aims. Mesenchymal stromal cells (MSCs) possess the ability to repair brain injuries. Additionally, nimodipine is a neuroprotective agent that increases cerebral blood flow and may help with the homing […]
Interferon gamma effect on immune mediator production in human nerve cells infected by two strains of Toxoplasma gondii
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Authors: Nour Mammari, Philippe Vignoles, Mohamad Adnan Halabi, Marie-Laure Dardé and Bertrand Courtioux.<br>Parasite Vol. 22 , page 39<br>Published online: 21/12/2015<br> Keywords: Toxoplasma gondii ; Human nerve cells ; IFN-γ ; Immunity.<img src="javascript:void(0);" height="»1″" width="»1″" alt="»»/"> from #Medicine via ola Kala on Inoreader http://ift.tt/1NGUxV3 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via […]
Osteonecrosis of the Jaw in Patients treated with Denosumab for Metastatic Tumors to the Bone: A Series of Thirteen Patients
Publication date: Available online 20 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Adepitan A. Owosho, Ariel Blanchard, Lauren Levi, Arvin Kadempour, Haley Rosenberg, SaeHee K. Yom, Azeez Farooki, Monica Fornier, Joseph M. Huryn, Cherry L. Estilo This case series describes the course of osteonecrosis of the jaw (ONJ) in thirteen patients with metastatic bone tumors treated solely with denosumab. Patients on denosumab may be more prone to developing ONJ even without a risk/precipitating factor and they may develop ONJ early in their denosumab therapy. The... περισσότερα »
The role of elective superficial parotidectomy in the treatment of temporal region squamous cell carcinoma
Abstract Objective In order to determine rates of metastasis and efficacy of elective superficial parotidectomy, we examine parotid specimens in patients with temporal region cutaneous squamous cell carcinoma treated with local excision and ipsilateral parotidectomy. Study design This paper is a retrospective review. Setting This study was conducted at a private tertiary referral practice in Fort Worth, Texas, from 1998 to 2013. Subjects and methods Ninety-three patients between ages 27 and 98 with primary squamous cell carcinoma of the temporal region greater than or equal to ... περισσότερα »
Synchronous ipsilateral adrenocortical carcinoma and renal cell carcinoma: a rare clinical entity
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Synchronous ipsilateral adrenocortical carcinoma (ACC) and renal cell carcinoma (RCC) are rare. Radiological imaging may not in all cases differentiate between the two tumours due to their proximity to each other. We encountered a case where preoperative diagnosis of renal cell carcinoma was made based on the radiological imaging but, following radical nephrectomy, this was […]
Floating iris cyst mimicking intravitreal cysticercosis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Description A 12-year-old girl presented with a history of repeated headaches (with no ocular symptoms) for 3 years. There was no history of ocular trauma or surgery. On ocular examination elsewhere, she was diagnosed as having intravitreal cysticercosis after observing a cyst in the left eye and was referred for vitrectomy to a tertiary eye […]
Rare cause of paraparesis: bilateral obturator neuropathy after hysterosalpingectomy
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Bilateral obturator nerve injury during pelvic surgery is an infrequent cause of lower limb paraparesis. We report the case of a 45-year-old woman with a large uterine leiomyoma who underwent simple total hysterectomy and bilateral salpingectomy. At 24 h after the surgery, the patient noticed loss of muscle strength when adducting both legs. She had […]
Thymoma complicated by deep vein thrombosis of the arm
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Description Our patient was referred urgently with an anterior neck lump. The patient was otherwise well with no history of smoking or radiation exposure. Initial investigation with ultrasound-guided aspiration cytology was suspicious and atypical for thyroid carcinoma. A CT scan demonstrated the neck lump was part of a 64x56x54 mm retrosternal mass infiltrating the superior […]
Two cases of small bowel obstruction secondary to a swallowed potato
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Bowel obstruction due to bezoars (compaction of ingested material within the gastrointestinal tract) is a rare, but well documented occurrence. In this paper, we present two cases of potato-induced small bowel obstruction. Both patients were approximately 50 years old and had cerebral palsy and learning disabilities, respectively. They presented with abdominal pain and bilious vomiting, […]
Combined pulmonary fibrosis and emphysema in hypersensitivity pneumonitis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Combined pulmonary fibrosis and emphysema is a distinct syndrome reported in patients who smoke. A 72-year-old, never-smoking female dairy farmer was referred for progressive dyspnoea on exertion, basal crackles on auscultation, normal spirometry and normal lung volumes but decreased diffusing capacity of the lung for carbon monoxide, centrilobular emphysema in the upper zones of the […]
t-BHQ Provides Protection against Lead Neurotoxicity via Nrf2/HO-1 Pathway
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The neurotoxicity of lead has been well established, and oxidative stress is strongly associated with lead-induced neurotoxicity. Nrf2 is important for protection against oxidative stress in many disease models. We applied t-BHQ, which is an Nrf2 activator, to investigate the possible role of Nrf2 in the protection against lead neurotoxicity. t-BHQ significantly attenuated the oxidative […]
A Novel Statistical Approach for Brain MR Images Segmentation Based on Relaxation Times
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Brain tissue segmentation in Magnetic Resonance Imaging is useful for a wide range of applications. Classical approaches exploit the gray levels image and implement criteria for differentiating regions. Within this paper a novel approach for brain tissue joint segmentation and classification is presented. Starting from the estimation of proton density and relaxation times, we propose […]
Mesenchymal Stem/Stromal Cells in Stromal Evolution and Cancer Progression
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The study of cancer biology has mainly focused on malignant epithelial cancer cells, although tumors also contain a stromal compartment, which is composed of stem cells, tumor-associated fibroblasts (TAFs), endothelial cells, immune cells, adipocytes, cytokines, and various types of macromolecules comprising the extracellular matrix (ECM). The tumor stroma develops gradually in response to the needs […]
Global Self-Propelled Sprayer Market 2015 Industry Trends, Growth, Analysis, Demand and Forecast
Global Self-Propelled Sprayer Industry 2015 The Global Self-Propelled Sprayer Industry report gives a comprehensive account of the Global Self-Propelled Sprayer market. Details such as the size, key players, segmentation, SWOT analysis, most influential trends, and business environment of the... from Infection via ola Kala on Inoreader http://ift.tt/1UVg9lp via IFTTT
A Novel Statistical Approach for Brain MR Images Segmentation Based on Relaxation Times
Brain tissue segmentation in Magnetic Resonance Imaging is useful for a wide range of applications. Classical approaches exploit the gray levels image and implement criteria for differentiating regions. Within this paper a novel approach for brain tissue joint segmentation and classification is presented. Starting from the estimation of proton density and relaxation times, we propose a novel method for identifying the optimal decision regions. The approach exploits the statistical distribution of the involved signals in the complex domain. The technique, compared to classical thre... περισσότερα »
The Effect of Perioperative Ischemia and Reperfusion on Multiorgan Dysfunction following Abdominal Aortic Aneurysm Repair
Abdominal aortic aneurysms (AAAs) are relatively common and are potentially life-threatening medical problems. The aim of this review is to provide an overview of the effect of I/R injury on multiorgan failure following AAA repair. The PubMed, CINAHL, EMBASE, Medline, Cochrane Review, and Scopus databases were comprehensively searched for articles concerning the pathophysiology of I/R and its systemic effects. Cross-referencing was performed using the bibliographies from the articles obtained. Articles retrieved were restricted to those published in English. One of the most promin...περισσότερα »
A fluorescent and colorimetric probe containing oxime-ether for Pd2+ in pure water and living cells
[image: GA?id=C5AN02225H] *Analyst*, 2016, Advance Article *DOI*: 10.1039/C5AN02225H, Communication Mian Wang, Yanglei Yuan, Hongmei Wang, Zhaohai Qin A coumarin based probe that contains oxime-ether (*1*) shows high selectivity and high sensitivity for Pd2+ in pure water and can ratiometrically image Pd2+ in living cells. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/1mvT1hP via IFTTT
Oxidative stress and oocyte quality: ethiopathogenic mechanisms of minimal/mild endometriosis-related infertility
Abstract Endometriosis, a highly prevalent gynecological disease, is often associated with infertility, even in its milder forms (minimal and mild endometriosis). However, no consensus has been established with regard to this relationship and the possible mechanisms involved have not been completely elucidated. The oocyte is believed to have an important role in the infertility presented by these patients. Hence, oxidative stress events associated with alterations in the peritoneal, serum and/or follicular microenvironments might result in poor oocyte quality and compromise the re... περισσότερα »
Preimplantation embryo-secreted factors modulate maternal gene expression in rat uterus
Abstract In mammalian reproduction, embryo implantation into the uterus is spatiotemporally regulated by a complex process triggered by a number of factors. Although previous studies have suggested that uterine receptivity is mediated by blastocyst-derived factors, specific functions of embryos remain to be defined during preimplantation. Therefore, the present study was conducted to identify the maternal genes regulated by embryo-secreted factors in the rat uterus. RNA-sequencing (RNA-seq) data revealed that 10 genes are up-regulated in the delayed implantation uterus compared wit...περισσότερα »
Spermiophages on testicular fine needle aspiration cytology: A rare finding
Macrophages usually reside in the testicular interstitial tissues and are normally not found within the seminiferous tubules. However, in certain cases of male infertility, the macrophages are activated and can then be found within the tubules where they can ingest spermatozoa and are labeled as "spermiophages." FNAC was performed in a 36 year male with history of primary infertility. On microscopy, smears made from right testis were indicative of hypospermatogenesis. On the contrary, smears made from the left testis were very cellular showing Sertoli cells and the entire spectru... περισσότερα »
Thymoma complicated by deep vein thrombosis of the arm
Description Our patient was referred urgently with an anterior neck lump. The patient was otherwise well with no history of smoking or radiation exposure. Initial investigation with ultrasound-guided aspiration cytology was suspicious and atypical for thyroid carcinoma. A CT scan demonstrated the neck lump was part of a 64x56x54 mm retrosternal mass infiltrating the superior vena cava and atrium (figure 1). Figure 1 CT scan demonstrating deep extension of retrosternal lesion into the anterior mediastinum, where a more focal 64x56x54 mm mass is seen. The mass is partly cystic, c... περισσότερα »
Two cases of small bowel obstruction secondary to a swallowed potato
Bowel obstruction due to bezoars (compaction of ingested material within the gastrointestinal tract) is a rare, but well documented occurrence. In this paper, we present two cases of potato-induced small bowel obstruction. Both patients were approximately 50 years old and had cerebral palsy and learning disabilities, respectively. They presented with abdominal pain and bilious vomiting, with no medical or surgical history. Diagnosis of small bowel obstruction was confirmed by CT prior to taking the patients to the operating theatre, where whole potatoes were found to be obstructing... περισσότερα »
Combined pulmonary fibrosis and emphysema in hypersensitivity pneumonitis
Combined pulmonary fibrosis and emphysema is a distinct syndrome reported in patients who smoke. A 72-year-old, never-smoking female dairy farmer was referred for progressive dyspnoea on exertion, basal crackles on auscultation, normal spirometry and normal lung volumes but decreased diffusing capacity of the lung for carbon monoxide, centrilobular emphysema in the upper zones of the lungs and diffuse infiltrative lung disease in the lower zones on high-resolution CT scan. Bronchoalveolar lavage differential cell count showed 35% lymphocytosis, and precipitating antibodies for *Wa...περισσότερα »
Biochemical clues may predict who develops Alzheimer’s disease — and who doesn’t
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Investigators have wondered why the brains of some cognitively-intact elderly individuals have abundant pathology on autopsy or significant amyloid deposition on neuroimaging that are… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QBkWK5 via IFTTT
A 120-year record of the spatial and temporal distribution of gravestone decay and acid deposition
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: February 2016 Source:Atmospheric Environment, Volume 127 Author(s): Howard D. Mooers, Avery R. Cota-Guertin, Ronald R. Regal, Anthony R. Sames, Amanda J. Dekan, Linnea M. Henkels This investigation examines the spatial and temporal variability of marble gravestone decay throughout West Midlands County and adjacent portions of Warwickshire, Staffordshire, and Worcestershire. Gravestone decay has been […]
Understanding how roadside concentrations of NOx are influenced by the background levels, traffic density, and meteorological conditions using Boosted Regression Trees
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: February 2016 Source:Atmospheric Environment, Volume 127 Author(s): Arwa Sayegh, James E. Tate, Karl Ropkins Oxides of Nitrogen (NOx) is a major component of photochemical smog and its constituents are considered principal traffic-related pollutants affecting human health. This study investigates the influence of background concentrations of NOx, traffic density, and prevailing meteorological conditions on […]
Synchronous ipsilateral adrenocortical carcinoma and renal cell carcinoma: a rare clinical entity
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Synchronous ipsilateral adrenocortical carcinoma (ACC) and renal cell carcinoma (RCC) are rare. Radiological imaging may not in all cases differentiate between the two tumours due to their proximity to each other. We encountered a case where preoperative diagnosis of renal cell carcinoma was made based on the radiological imaging but, following radical nephrectomy, this was […]
Floating iris cyst mimicking intravitreal cysticercosis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Description A 12-year-old girl presented with a history of repeated headaches (with no ocular symptoms) for 3 years. There was no history of ocular trauma or surgery. On ocular examination elsewhere, she was diagnosed as having intravitreal cysticercosis after observing a cyst in the left eye and was referred for vitrectomy to a tertiary eye […]
Rare cause of paraparesis: bilateral obturator neuropathy after hysterosalpingectomy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Bilateral obturator nerve injury during pelvic surgery is an infrequent cause of lower limb paraparesis. We report the case of a 45-year-old woman with a large uterine leiomyoma who underwent simple total hysterectomy and bilateral salpingectomy. At 24 h after the surgery, the patient noticed loss of muscle strength when adducting both legs. She had […]
Thymoma complicated by deep vein thrombosis of the arm
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Description Our patient was referred urgently with an anterior neck lump. The patient was otherwise well with no history of smoking or radiation exposure. Initial investigation with ultrasound-guided aspiration cytology was suspicious and atypical for thyroid carcinoma. A CT scan demonstrated the neck lump was part of a 64x56x54 mm retrosternal mass infiltrating the superior […]
Two cases of small bowel obstruction secondary to a swallowed potato
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Bowel obstruction due to bezoars (compaction of ingested material within the gastrointestinal tract) is a rare, but well documented occurrence. In this paper, we present two cases of potato-induced small bowel obstruction. Both patients were approximately 50 years old and had cerebral palsy and learning disabilities, respectively. They presented with abdominal pain and bilious vomiting, […]
Combined pulmonary fibrosis and emphysema in hypersensitivity pneumonitis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Combined pulmonary fibrosis and emphysema is a distinct syndrome reported in patients who smoke. A 72-year-old, never-smoking female dairy farmer was referred for progressive dyspnoea on exertion, basal crackles on auscultation, normal spirometry and normal lung volumes but decreased diffusing capacity of the lung for carbon monoxide, centrilobular emphysema in the upper zones of the […]
Editorial Board
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: January 2016 Source:Cytotherapy, Volume 18, Issue 1 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22k9qGB via IFTTT
PulmCrit- Neurocritical care of the comatose meningitis patient
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: cropped.jpg?resize=750%2C272] Early in my training I had a few comatose meningitis patients. They were admitted, given antibiotics, and supported on a ventilator. They died. For a while, I believed that this condition was fairly hopeless. Then I encountered a comatose young man with meningitis due to adjacent mastoiditis. His lumbar puncture opening pressure was ~50cm. Following mastoidectomy and temporary placement of a lumbar drain, he recovered. Since then, I have been increasingly aggressive about managing this. Some patients have responded surprisingly well. EMCrit b...περισσότερα »
Osteonecrosis of the Jaw in Patients treated with Denosumab for Metastatic Tumors to the Bone: A Series of Thirteen Patients
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Publication date: Available online 20 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Adepitan A. Owosho, Ariel Blanchard, Lauren Levi, Arvin Kadempour, Haley Rosenberg, SaeHee K. Yom, Azeez Farooki, Monica Fornier, Joseph M. Huryn, Cherry L. Estilo This case series describes the course of osteonecrosis of the jaw (ONJ) in thirteen patients with metastatic bone tumors […]
Screening auf Frühgeburtlichkeit und Präeklampsie
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Quo vadis? Trotz intensiver Bemühungen konnte die Prävalenz von Frühgeburtlichkeit und Präeklampsie nicht gesenkt werden – und somit auch nicht die damit verbundene maternale wie fetale Morbidität und Mortalität. Wird sich das in Zukunft ändern? from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1MqTnLx via IFTTT
Screening auf Frühgeburtlichkeit und Präeklampsie
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Quo vadis? Trotz intensiver Bemühungen konnte die Prävalenz von Frühgeburtlichkeit und Präeklampsie nicht gesenkt werden – und somit auch nicht die damit verbundene maternale wie fetale Morbidität und Mortalität. Wird sich das in Zukunft ändern? from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1MqTnLx via IFTTT
An objective measurement to identify individuals at risk of developing depression?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
New study suggests a potential biomarker in the brain.A network of interacting brain regions known as the default mode network (DMN) was found to have stronger connections in adults and children… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1JnT3x8 via IFTTT
Stroke recovery in mice improved by Ambien, Stanford study shows
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Mice that had strokes rebounded significantly faster if they received low doses of a popular sleeping aid, according to researchers at the Stanford University School of Medicine. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OFPh3O via IFTTT
Grid cells: Reading the neural code for space
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
One year ago, the Nobel Prize in Physiology or Medicine went to the discoverers of the mammalian «GPS system» for spatial navigation. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QELJoJ via IFTTT
An objective measurement to identify individuals at risk of developing depression?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
New study suggests a potential biomarker in the brain.A network of interacting brain regions known as the default mode network (DMN) was found to have stronger connections in adults and children… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1JnT3x8 via IFTTT
Stroke recovery in mice improved by Ambien, Stanford study shows
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Mice that had strokes rebounded significantly faster if they received low doses of a popular sleeping aid, according to researchers at the Stanford University School of Medicine. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OFPh3O via IFTTT
Grid cells: Reading the neural code for space
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
One year ago, the Nobel Prize in Physiology or Medicine went to the discoverers of the mammalian «GPS system» for spatial navigation. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QELJoJ via IFTTT
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