Anti-BP180-type mucous membrane pemphigoid (MMP)
Anti-BP180-type mucous membrane pemphigoid: report of two cases: AbstractWe describe two patients with anti-BP180-type mucous membrane pemphigoid (MMP), who were correctly diagnosed and treated in early stages through the cooperation of dentists and dermatologists. Patient 1 was a 74-year-old woman who visited our dental department due to blisters over the oral mucosa and eruptions on the skin. She had also experienced bleeding of the gingiva and palate mucosa. Biopsy specimens from the oral mucosa revealed detachment of epithelial basement membrane and subepithelial lamina propria... περισσότερα »
PLGA-coated beta-tricalcium phosphate on the healing of calvarial bone defects
Effect of poly (lactide-co-glycolide) (PLGA)-coated beta-tricalcium phosphate on the healing of rat calvarial bone defects: a comparative study with pure-phase beta-tricalcium phosphate: Abstract Objectives To investigate the effect of poly (lactide-co-glycolide) (PLGA)-coated β-tricalcium phosphate (TCP) as a scaffold on bone regeneration in rat calvaria. Material and Methods Bilateral critical-sized defects were created in the calvaria of 20 Sprague Dawley rats. Defects of each rat were filled with pure-phase β-TCP or PLGA/β-TCP, or left as unfilled control. The healing was evalua... περισσότερα »
Bacterial influence on consolidation of bone grafts in maxillary sinus elevation
Bacterial influence on consolidation of bone grafts in maxillary sinus elevation: [image: cover.gif?v=1&s=2eb91ab0c0aac4a9489c87d3] Abstract Objectives The aim of this study was to identify microorganisms present on the maxillary sinus floor at the moment of sinus elevation surgery and, using tomography, to investigate the repercussions these might have for regenerated bone 9 months after the procedure. Materials and methods 174 patients (90 women and 84 men) with a mean age of 55.92 years underwent 227 sinus elevations (120 left sinus, 107 right sinus). As the membrane was lift... περισσότερα »
Vowel identification and vowel formant discrimination
English vowel identification and vowel formant discrimination by native Mandarin Chinese- and native English-speaking listeners: the effect of vowel duration dependence via Hearing Research Publication date: Available online 6 January 2016 *Source:*Hearing Research Author(s): Lin Mi, Sha Tao, Wenjing Wang, Qi Dong, Jingjing Guan, Chang Liu The purpose of this study was to examine the relationship between English vowel identification and English vowel formant discrimination for native Mandarin Chinese- and native English-speaking listeners. The identification of 12 English vowels was me...περισσότερα »
Local dynamic stability in walking while texting and performing an arithmetical problem
The reliability of via Gait & Posture Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Dennis Hamacher, Daniel Hamacher, Alexander Törpel, Martin Krowicki, Fabian Herold, Lutz Schega In the recent years, local dynamic stability of walking was frequently used to quantify motor control. Particularly, dual-task paradigms are used to assess a shift in gait control strategy to test walking in real life situations. Texting short messages while walking is a common motor-cognitive dual task of daily living. To able to monitor possible intervention effects on moto... περισσότερα »
Age-related decline of gait variability in children with attention-deficit/hyperactivity disorder
: Support for the maturational delay hypothesis in gait via Gait & Posture Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Olivia Manicolo, Alexander Grob, Sakari Lemola, Priska Hagmann-von Arx BackgroundPrevious findings showed a tendency toward higher gait variability in children with attention-deficit/hyperactivity disorder (ADHD) compared to controls. This study examined whether gait variability in children with ADHD eventually approaches normality with increasing age (delay hypothesis) or whether these gait alterations represent a persistent deviatio... περισσότερα »
The Journal of the Acoustical Society of America
Impulse source localization in an urban environment: Time reversal versus time matching source Sub-harmonic broadband humps and tip noise in low-speed ring fans harmonics In-plane and out-of-plane motions of the human tympanic membrane holographic techniques Acoustic impedance of micro perforated membranes: Velocity continuity condition at the perforation boundary model Characterizing large river sounds: Providing context for understanding the environmental effects of noise produced by hydrokinetic turbines Underwater Sequential inversion of modal data for sound attenuation in sediment a...περισσότερα »
In-plane and out-of-plane motions of the human tympanic membrane
In-plane and out-of-plane motions of the human tympanic membrane by Morteza Khaleghi, Jeffrey Tao Cheng, Cosme Furlong and John J. Rosowski via The Journal of the Acoustical Society of America: Most Recent Articles Computer-controlled digital holographic techniques are developed and used to measure shape and four-dimensional nano-scale displacements of the surface of the tympanic membrane (TM) in cadaveric human ears in response to tonal sounds. The combination of these measurements (shape and sound-induced motions) allows the calculation of the out-of-plane (perpendicular to the surf... περισσότερα »
Sub-harmonic broadband humps and tip noise
Sub-harmonic broadband humps and tip noise in low-speed ring fans by Stéphane Moreau and Marlène Sanjose via The Journal of the Acoustical Society of America: Most Recent Articles A joint experimental and numerical study has been achieved on a low-speed axial ring fan in clean inflow. Experimental evidence shows large periodic broadband humps at lower frequencies than the blade passing frequencies and harmonics even at design conditions. These sub-harmonic humps are also found to be sensitive to the fan process and consequently to its tip geometry. Softer fans yield more intense humps... περισσότερα »
Impulse source localization in an urban environment
: Time reversal versus time matching by Sylvain Cheinet, Loïc Ehrhardt and Thierry Broglin via The Journal of the Acoustical Society of America: Most Recent Articles This study investigates two approaches for localizing an impulse sound source with distributed sensorsin an urban environment under controlled processing time. In both approaches, the numerical modelused for calculating the sound propagation is a finite-difference time-domain(FDTD)model. The simulations are drastically accelerated by restricting to the lower frequencies of the impulse signals and are evaluated against in...περισσότερα »
The hippocampus may be more susceptible to environmental noise
The hippocampus may be more susceptible to environmental noise than the auditory cortex via Hearing Research Publication date: Available online 7 January 2016 *Source:*Hearing Research Author(s): Liang Cheng, Shao-Hui Wang, Yun huang, Xiao-Mei Liao Noise exposure can cause structural and functional problem in the auditory cortex (AC) and hippocampus, the two brain regions in the auditory and non-auditory systems respectively. The aim of the present study was to explore which one of these two brain regions may be more susceptible to environmental noise. The AC and hippocampus of mice we... περισσότερα »
BRCA1/2 Mutations Associated with Progression-Free Survival in Ovarian Cancer Patients in the AGO-OVAR 16 Study.
*BRCA1/2 Mutations Associated with Progression-Free Survival in Ovarian Cancer Patients in the AGO-OVAR 16 Study.* Gynecol Oncol. 2015 Dec 28; Authors: Harter P, Johnson T, Berton-Rigaud D, Park SY, Friedlander M, Del Campo JM, Shimada M, Forget F, Mirza MR, Colombo N, Zamagni C, Chan JK, Imhof M, Herzog TJ, O'Donnell D, Heitz F, King K, Stinnett S, Barrett C, Jobanputra M, Xu CF, du Bois A Abstract OBJECTIVE: AGO-OVAR 16 demonstrated that pazopanib maintenance therapy significantly increased progression-free survival (PFS) in patients with ovarian cancer whose disease had not p... περισσότερα »
Breed Distribution and Clinical Characteristics of B Cell Chronic Lymphocytic Leukemia in Dogs.
*Breed Distribution and Clinical Characteristics of B Cell Chronic Lymphocytic Leukemia in Dogs.* J Vet Intern Med. 2016 Jan 6; Authors: Bromberek JL, Rout ED, Agnew MR, Yoshimoto J, Morley PS, Avery AC Abstract BACKGROUND: B-cell chronic lymphocytic leukemia (B-CLL) is the most common hematopoietic malignancy in humans in the developed world and the primary risk factor is genetic. Dogs also develop B-CLL, but there is no systematic description of the disease in dogs. Understanding the epidemiology of B-CLL in dogs may help practitioners recognize the disease and position the dog... περισσότερα »
Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.
*Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.* J Immunol. 2016 Jan 6; Authors: Younis RH, Han KL, Webb TJ Abstract One of the mechanisms by which malignancies can induce immune suppression is through the production of cytokines that affect the maturation and differentiation of inflammatory cells in the tumor microenvironment. Semaphorin 4D (Sema4D) is a proangiogenic cytokine produced by several malignancies, which has been described in the regulation of the immune system. In the present study, we exa... περισσότερα »
Quality of Life in Survivors of Pediatric Cancer and Their Siblings: The Consensus Between Parent-Proxy and Self-Reports.
*Quality of Life in Survivors of Pediatric Cancer and Their Siblings: The Consensus Between Parent-Proxy and Self-Reports.* Pediatr Blood Cancer. 2016 Jan 6; Authors: Schulte F, Wurz A, Reynolds K, Strother D, Dewey D Abstract OBJECTIVES: To examine the discrepancy between survivor-parent and sibling-parent reports of health-related quality of life (HRQL) and the level of agreement (i.e., correlation) between child reports (i.e., survivor and sibling) and parent-proxy reports of HRQL. METHODS: Fifty-one families participated. Pediatric cancer survivors (49% male; 6-18 years of ag... περισσότερα »
A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer.
*A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer.* Sci Transl Med. 2016 Jan 6;8(320):320ra4 Authors: Whitley MJ, Cardona DM, Lazarides AL, Spasojevic I, Ferrer JM, Cahill J, Lee CL, Snuderl M, Blazer DG, Hwang ES, Greenup RA, Mosca PJ, Mito JK, Cuneo KC, Larrier NA, O'Reilly EK, Riedel RF, Eward WC, Strasfeld DB, Fukumura D, Jain RK, Lee WD, Griffith LG, Bawendi MG, Kirsch DG, Brigman BE Abstract Local recurrence is a common cause of treatment failure for patients with solid tumors. Intraoperative detection of microscopic resi... περισσότερα »
Cryopreservation of microencapsulated murine mesenchymal stem cells genetically engineered to secrete erythropoietin.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Cryopreservation of microencapsulated murine mesenchymal stem cells genetically engineered to secrete erythropoietin.* Int J Pharm. 2015 May 15;485(1-2):15-24 Authors: Gurruchaga H, Ciriza J, Saenz Del Burgo L, Rodriguez-Madoz JR, Santos E, Prosper F, Hernández RM, Orive G, Pedraz JL Abstract The ability to cryopreserve and store for long term the structure and function of therapeutic cells and tissues plays a pivotal role in clinical medicine. In fact, it is an essential pre-requisite for the commercial and clin...περισσότερα »
The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics.
*The Challenge of Cancer Genomics in Rare Nervous System Neoplasms: Malignant Peripheral Nerve Sheath Tumors as a Paradigm for Cross-Species Comparative Oncogenomics.* Am J Pathol. 2015 Dec 28; Authors: Carroll SL Abstract Comprehensive genomic analyses of common nervous system cancers provide new insights into their pathogenesis, diagnosis, and treatment. Although analogous studies of rare nervous system tumors are needed, there are major barriers to performing such studies. Cross-species comparative oncogenomics, identifying driver mutations in mouse cancer models and validat... περισσότερα »
Primary genitourinary melanoma: Epidemiology and disease-specific survival in a large population-based cohort.
*Primary genitourinary melanoma: Epidemiology and disease-specific survival in a large population-based cohort.* Urol Oncol. 2015 Dec 28; Authors: Sanchez A, Rodríguez D, Allard CB, Bechis SK, Sullivan RJ, Boeke CE, Kuppermann D, Cheng JS, Barrisford GW, Preston MA, Feldman AS Abstract BACKGROUND: Primary genitourinary (GU) melanoma is a rare disease, which is poorly characterized. OBJECTIVE: To examine clinical characteristics and survival outcomes of primary GU melanoma among men and women. DESIGN, SETTING, AND PARTICIPANTS: Retrospective study using the Surveillance, Epidemiol... περισσότερα »
Increased risk of tumor in DM1 is not related to exposure to common lifestyle risk factors.
*Increased risk of tumor in DM1 is not related to exposure to common lifestyle risk factors.* J Neurol. 2016 Jan 6; Authors: Bianchi ML, Leoncini E, Masciullo M, Modoni A, Gadalla SM, Massa R, Rastelli E, Terracciano C, Antonini G, Bucci E, Petrucci A, Costanzi S, Santoro M, Boccia S, Silvestri G Abstract Recent studies documented an increased risk of neoplasm in patients with myotonic dystrophies (DM). Yet, none of these studies evaluated the contribution of common cancer risk factors in such observation. In this study, we included a cohort of patients (n = 255) with an establi...περισσότερα »
Alternative Methods for Nasotracheal Intubation and Extubation in a Patient With Apert Syndrome.
[image: http:--allenpress.com-system-files-image] Related Articles *Alternative Methods for Nasotracheal Intubation and Extubation in a Patient With Apert Syndrome.* Anesth Prog. 2015;62(3):122-4 Authors: Tsukamoto M, Yokoyama T Abstract Apert syndrome is a rare autosomal dominant disorder characterized by craniofacial abnormalities, craniosynostosis and syndactyly. Nasotracheal intubation for a patient with Apert syndrome can be a challenge because of abnormal facial anatomy. We experienced the anesthetic management of a patient with Apert syndrome who underwent partial resectio... περισσότερα »
Spontaneous hyphaema secondary to bleeding from an iris vascular tuft in a patient with a supratherapeutic International normalised ratio: case report.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Spontaneous hyphaema secondary to bleeding from an iris vascular tuft in a patient with a supratherapeutic International normalised ratio: case report.* BMC Ophthalmol. 2015;15:60 Authors: Ooi KG, Gupta R, Wang SB, Dance S, Borovik A, Francis IC Abstract BACKGROUND: Iris vascular tufts are rare iris stromal vascular hamartomas. Patients with iris vascular tufts generally remain asymptomatic until presenting with a spontaneous hyphaema or with mild intraoperative pupil margin haemorrhage... περισσότερα »
Leiomyomatosis peritonealis disseminata positive for progesterone receptor.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Leiomyomatosis peritonealis disseminata positive for progesterone receptor.* Am J Case Rep. 2015;16:300-4 Authors: Yuri T, Kinoshita Y, Yuki M, Yoshizawa K, Emoto Y, Tsubura A Abstract BACKGROUND: Leiomyomatosis peritonealis disseminata (LPD) is a rare condition that occurs in reproductive-age women. The pathogenesis of LPD is considered to be related to female sex hormones. CASE REPORT: A 30-year-old woman who had undergone an ovariectomy due to calcified thecoma at 24 years of age and had delivered a baby boy at 29 years o... περισσότερα »
Endometrial metastasis of lung adenocarcinoma: a report of two cases.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Endometrial metastasis of lung adenocarcinoma: a report of two cases.* Am J Case Rep. 2015;16:296-9 Authors: Ahmad Z, Raza A, Patel MR Abstract BACKGROUND: The female genital tract is an uncommon site of involvement for extragenital malignancies. Ovarian, vaginal, and cervical metastasis has been described in the literature. Uterine corpus and, particularly, endometrial involvement are exceedingly rare. As the incidence of lung cancer is rising in the female population, metastatic uterine involvement by lung cancer is also b... περισσότερα »
Pulmonary metastasis in a patient with simultaneous bladder cancer and relapsing granulomatosis with polyangiitis.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Pulmonary metastasis in a patient with simultaneous bladder cancer and relapsing granulomatosis with polyangiitis.* Am J Case Rep. 2015;16:287-91 Authors: Danckers M, Zhou F, Nimeh D, Belmont HM, Steiger DJ Abstract BACKGROUND: Granulomatosis with polyangiitis (GPA) relapse can complicate the differential diagnosis of pulmonary lesions. CASE REPORT: A 70-year-old male smoker with GPA and emphysema presented with dyspnea, dry cough, and a right upper lobe pulmonary ground-glass opacity that persisted despite antibiotics. A tra... περισσότερα »
A case of radiation-induced generalized morphea with prominent mucin deposition and tenderness.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *A case of radiation-induced generalized morphea with prominent mucin deposition and tenderness.* Am J Case Rep. 2015;16:279-82 Authors: Yanaba K, Umezawa Y, Nakagawa H Abstract BACKGROUND: Radiation-induced morphea is a rare complication of radiation therapy. The affected areas are generally restricted to the radiation field or to the nearby surrounding area. CASE REPORT: A 67-year-old Japanese woman with a history of right breast cancer followed by adjuvant radiotherapy was referred our hospital because of 7-year history of...περισσότερα »
Late postoperative myelomalacic myelopathy.
[image: http:--http://ift.tt/1feGv2I] Related Articles *Late postoperative myelomalacic myelopathy.* Spinal Cord. 2015 Mar;53 Suppl 1:S27-9 Authors: de Carvalho B, Barros P, Pereira P, Vaz R Abstract STUDY DESIGN: This is a case report. OBJECTIVES: Spinal cord atrophy presenting with late progressive myelopathy after many years of clinical stability is a rare and unexplained phenomenon after cervical spine surgery. The authors report and discuss the etiologies and outcomes of late postoperative myelomalacic myelopathy. SETTING: This study was conducted in the Department of Neurosur...περισσότερα »
Jugulotympanic paraganglioma: a rare cause of vertigo.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Jugulotympanic paraganglioma: a rare cause of vertigo.* Am J Case Rep. 2015;16:228-31 Authors: Jehangir A, Pathak R, Shaikh B, Salman A, Fareedy SB, Qureshi A, Jehangir Q, Alweis R Abstract BACKGROUND: Jugulotympanic paraganglioma generally presents in the 5th or 6th decades of life with tinnitus and hearing loss. In this manuscript, we present a rare case of jugulotympanic paraganglioma presenting in the 9th decade with vertigo as the most bothersome symptom. CASE REPORT: An 83-year-old woman presented with worsening episode...περισσότερα »
A 3D-printed functioning anatomical human middle ear model
A 3D-printed functioning anatomical human middle ear model via Hearing Research Publication date: Available online 7 January 2016 *Source:*Hearing Research Author(s): Ismail Kuru, Hannes Maier, Mathias Müller, Thomas Lenarz, Tim C. Lueth The middle ear is a sophisticated and complex structure with a variety of functions, yet a delicate organ prone to injuries due to various reasons. Both, understanding and reconstructing its functions has always been an important topic for researchers from medical and technical background. Currently, human temporal bones are generally used as model for...περισσότερα »
Gait & Posture
Usual walking speed and all-cause mortality risk in older people: A systematic review and meta-analysis Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Bing Liu, Xinhua Hu, Qiang Zhang, Yichuan Fan, Jun Li, Rui Zou, Ming Zhang, Xiuqi Wang, Junpeng Wang The purpose of this study was to investigate the relationship between slow usual walking speed and all-cause mortality risk in older people by conducting a meta-analysis. We searched through the Pubmed, Embase and Cochrane Library database up to March 2015. Only prospective observational studies that ...περισσότερα »
Surgical repair of nasal septal perforations
Surgical repair of nasal septal perforations: an update.: Purpose of review: Nasal septal perforations can have a substantial impact on patient's nasal breathing and subsequent quality of life. Various surgical techniques have previously been described for the repair of these perforations. In this review, we examine the most recent literature evaluating surgical techniques for the repair of nasal septal perforations. Recent findings: Twenty-seven studies evaluating 646 patients were included. None of these studies compared different surgical techniques. Four major categories of surgi... περισσότερα »
Die Verteilung und Streuung von APHAB-Antworten vor und nach einer Hörgeräteversorgung
Die Verteilung und Streuung von APHAB-Antworten vor und nach einer Hörgeräteversorgung: Laryngo-Rhino-Otol DOI: 10.1055/s-0041-107561 Einleitung: Inventare sind Bestandteil in der audiologischen Diagnostik. Der APHAB wird regelmäßig im Rahmen einer Hörgeräteversorgung in Deutschland angewendet. Diese Studie untersucht, ob es bestimmte APHAB-Fragen gibt, die gegenüber anderen seltener beantwortet werden und ob die inverse Formulierung mancher Fragen einen Einfluss darauf hat. Methoden: Zwischen April 2013 und August 2015 wurden bei 23 557 APHAB-Fragebögen aus 10 Kassenärztlichen Ve... περισσότερα »
Das stimmliche Selbstbild (FESS) bei Studierenden der Medizin
Das stimmliche Selbstbild (FESS) bei Studierenden der Medizin: Laryngo-Rhino-Otol DOI: 10.1055/s-0041-109406 Einführung: Der 2015 publizierte Fragebogen zur Erfassung des Stimmlichen Selbstbilds FEES? von Nusseck et al. erfasst mit 17 Items die 3 Skalen „Beziehung zur eigenen Stimme“, „Bewusstheit im Umgang mit der eigenen Stimme“ und „Stimme und Emotion“. Die vorliegende Arbeit soll ein Bild von der normalen Verteilung dieser Skalenwerte an jungen Erwachsenen erfassen. Material und Methoden: 96 FESS-Fragebögen wurden von Studierenden der Medizin ausgefüllt, zusätzlich um ein weite... περισσότερα »
Unilateralen Cochlea-Implantatversorgung
Kostenanalyse der unilateralen Cochlea-Implantatversorgung bei Erwachsenen: Laryngo-Rhino-Otol DOI: 10.1055/s-0035-1555936 Hintergrund: Die Zahl der Cochlea-Implantationen (CI) ist in den letzten Jahren stetig gestiegen. Die Ursachen hierfür liegen in einer Erweiterung der Indikationskriterien, dem demografischen Wandel, gestiegenen Lebensqualitätsansprüchen der Patienten und der gestiegenen Akzeptanz der Methode, dies vor allem durch eine verbesserte Hörleistung aufgrund technologischen Fortschritts. Die Konsequenz sind steigende Ausgaben der gesetzlichen Krankenversicherung (GKV)... περισσότερα »
Customized Prosthesis for Irregularly Formed Tracheostoma After Laryngectomy
Evaluation of Customized Prosthesis for Irregularly Formed Tracheostoma After Laryngectomy: Background: After laryngectomy, the tracheostoma forms the functional center for breathing and phonation. An occasionally occurring but typical problem can arise from an oversized and/or irregularly formed tracheostoma, hampering the temporary occlusion necessary for sufficient speech production. As an alternative to a surgical correction of the tracheostoma, an individually adjusted stoma silicone prosthesis may be used. Materials and Methods: Twenty-one patients suffering from irregularly ...περισσότερα »
Bilateral Cochlear Implantation in a Child With X-Linked Deafness
Positive Outcomes and Surgical Strategies for Bilateral Cochlear Implantation in a Child With X-Linked Deafness: Objectives: To recognize that bilateral cochlear implantation (CI) in X-linked deafness is safe, describe techniques to maximize successful electrode placement and minimize surgical risks, and recognize that normalization of hearing as well as language acquisition is achievable. Methods: A 6-month-old male patient presented with bilateral profound sensorineural hearing loss and was confirmed to have X-linked deafness secondary to *POU3F4* gene mutation. Due to lack of be...περισσότερα »
Small Intestinal Submucosa Implantation for the Possible Treatment of Vocal Fold Scar, Sulcus, and Superficial Lamina Propria Atrophy
Small Intestinal Submucosa Implantation for the Possible Treatment of Vocal Fold Scar, Sulcus, and Superficial Lamina Propria Atrophy: Objectives: Evaluate the histologic effects of grafting porcine-derived small intestinal submucosa (SIS) into the vocal fold superficial lamina propria (SLP) layer for the potential treatment of vocal fold scar, sulcus and superficial lamina propria atrophy. Methods: Small intestinal submucosa was implanted into the right vocal fold SLP of 6 mongrel dogs. The left vocal fold served as a sham surgical control. At 2, 4, and 6 weeks postoperative, bila... περισσότερα »
The endotracheal sheathed bronchoscope is a safe and efficacious technique for challenging airway foreign bodies complicated by a patient’s limited pulmonary reserve
Positive Pressure Bronchoscopy Technique: Case Report: Objective: Foreign body aspiration into the tracheobronchial tree continues to be a challenging problem for otolaryngologists. This is especially true in patients with poor pulmonary reserve. Methods: We describe a novel technique in which an endotracheal sheathed bronchoscope is used as a means to provide positive pressure ventilation simultaneously during foreign body extraction. Results: This new technique afforded the bronchoscopist more time during retrieval of the foreign body where previous attempts were limited by rapi... περισσότερα »
Functional Electrical Stimulation of the Feline Larynx With a Flexible Ribbon Electrode Array
Functional Electrical Stimulation of the Feline Larynx With a Flexible Ribbon Electrode Array: Objectives: Success of laryngeal reanimation through neurorrhaphy has been limited by synkinesis and preoperative muscle atrophy. The objective of this study was to investigate the use of epimysial electrode arrays as a means of delivering electrical stimulation to the posterior cricoarytenoid muscles in order to control laryngeal abduction. Methods: Ribbon electrode arrays with 4 or 8 electrode contacts were used. Four cats underwent implantation of electrode arrays along the surface of ... περισσότερα »
Quality of Life Questionnaire for Patients With Head and Neck Cancer
Cross-cultural and Moroccan Validation of the University of Washington Quality of Life Questionnaire for Patients With Head and Neck Cancer: Objectives: To translate the original English version of the University of Washington Quality of Life (UW-QOL) questionnaire into Moroccan Arabic version and investigate its psychometric validity and reliability for Moroccan-speaking patients with head and neck cancer. Methods: The UW-QOL was conducted in 104 patients treated for head and neck cancer in the department of head and neck surgery, Ibn Rochd university hospital, Casablanca. A cont... περισσότερα »
Robot-Assisted Neck Dissection Through a Modified Facelift Incision
Robot-Assisted Neck Dissection Through a Modified Facelift Incision: Objectives: The aim of this study is to describe the feasibility as well as oncologic outcomes of robot-assisted neck dissection (RAND) through a modified facelift incision in an American population. Study Design: Retrospective case series. Setting: University tertiary care hospital. Methods: All patients who underwent RAND between November 2012 and December 2014 were included. Medical records were reviewed for demographics, medical histories, staging, operative information, postoperative hospital course and c... περισσότερα »
Collagen Sponge Scaffolds on Tracheal Epithelium Regeneration
Effect of Structural Differences in Collagen Sponge Scaffolds on Tracheal Epithelium Regeneration: Objective: We developed an in situ regeneration-inducible artificial trachea composed of a porcine collagen sponge and polypropylene framework and used it for tracheal reconstruction. In the present study, collagen sponges with different structures were prepared from various concentrations of collagen solutions, and their effect on the regeneration of tracheal epithelium was examined. Methods: Collagen sponges were prepared from type I and III collagen solutions. The structures of th... περισσότερα »
Wire Brush Bristle Ingestion
Management of Wire Brush Bristle Ingestion: Review of Literature and Presentation of an Algorithm: Objectives: To increase awareness of wire brush bristle ingestion, review the literature relating to wire brush bristle ingestion, and describe an algorithm for management of wire brush bristle foreign bodies as well as a technique for bedside removal. Methods: The authors present a case of an accidental wire bristle ingestion that was successfully treated with bedside removal and describe a successful bedside technique for removal. For the literature review, the PubMed journal datab... περισσότερα »
How staging of thin melanoma is changed after the introduction of TNM 7th edition: a population-based analysis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Abstract Introduction In 2009, the American Joint Committee on Cancer (AJCC) incorporated the tumor mitotic rate in the melanoma pathological TNM staging system. To investigate the effect of this change on the pT1 substaging of primary cutaneous melanomas, we reclassified the cases collected by a cancer registry according to the 6th and the 7th editions […]
A systematic literature review of the key challenges for developing the structure of public health economic models
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Abstract Objectives To identify the key methodological challenges for public health economic modelling and set an agenda for future research. Methods An iterative literature search identified papers describing methodological challenges for developing the structure of public health economic models. Additional multidisciplinary literature searches helped expand upon important ideas raised within the review. Results Fifteen articles […]
Alzheimer’s treatment clue found in brain inflammation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
A study of mice suggests blocking a protein important for controlling immune cells in the brain could halt or limit memory loss and other damage seen in Alzheimer’s disease. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1K20D0R via IFTTT
Risk factors for outcome in refractory acute myeloid leukemia patients treated with a combination of fludarabine, cytarabine, and amsacrine followed by a reduced-intensity conditioning and allogeneic stem cell transplantation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Abstract Introduction Hematopoietic stem cell transplantation (HCT) is considered a standard treatment for high-risk acute myeloid leukemia (AML) in first or second complete remission (CR). Unfortunately, not all patients achieve complete remission prior to HCT. We sought to establish predictive factors for survival after HCT for refractory AML after FLAMSA-RIC. Patients and methods We analyzed […]
Odds are good that risky gambling choices are influenced by a single brain connection
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
One person’s risky bet is another’s exciting opportunity.The difference between those outlooks comes down to more than just disposition: It turns out that people with a stronger connection… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1K236IF via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1n7HIN5 via IFTTT
Odds are good that risky gambling choices are influenced by a single brain connection
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
One person’s risky bet is another’s exciting opportunity.The difference between those outlooks comes down to more than just disposition: It turns out that people with a stronger connection… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1K236IF via IFTTT
Drastic morphological and molecular differences between lymph node micrometastatic tumors and macrometastatic tumors of lung adenocarcinoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Abstract Purpose The expansion of micrometastatic tumors to macrometastatic ones is thought to be tightly regulated by several microenvironmental factors. The aim of this study was to elucidate the morphological and phenotypical differences between micrometastatic and macrometastatic tumors. Method We first examined the morphological characteristics of 66 lymph node (LN) micrometastatic tumors (less than 2 […]
Extensive Metoidioplasty as a Technique Capable of Creating a Compatible Analogue to a Natural Penis in Female Transsexuals
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Abstract Objective To introduce the operative technique of “extensive metoidioplasty” (EM) in female transsexual surgery, for achieving an effective reconstruction of a male-appearing, normally functioning, fully sensate and erectile external genitalia. Patients and Methods Ten female transsexuals (46 xx karyotype) between the ages of 20 and 40 years underwent EM as their sex reassignment surgical […]
Octreotide and Lanreotide in Gastroenteropancreatic Neuroendocrine Tumors
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Abstract Neuroendocrine tumors are heterogeneous, rare malignancies that arise most commonly in the gastrointestinal tract and pancreas. They often secrete vasoactive substances resulting in carcinoid syndrome and the tumor cells exclusively express somatostatin receptors. Octreotide and lanreotide are the two synthetic somatostatin analogs used for the control of carcinoid symptoms and tumor progression in advanced […]
Evaluation of individually body weight adapted contrast media injection in coronary CT-angiography
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Publication date: Available online 7 January 2016 Source:European Journal of Radiology Author(s): Casper Mihl, Madeleine Kok, Sibel Altintas, Bas L.J.H. Kietselaer, Jakub Turek, Joachim E. Wildberger, Marco Das ObjectivesContrast media (CM) injection protocols should be customized to the individual patient. Aim of this study was to determine if software tailored CM injections result in diagnostic […]
Sustained-Exposure Ciprofloxacin for Intratympanic Injection During Tympanostomy Tube Surgery
Randomized Clinical Trial of a Sustained-Exposure Ciprofloxacin for Intratympanic Injection During Tympanostomy Tube Surgery: Objective: This exploratory clinical trial evaluated the safety and clinical activity of a novel, sustained-exposure formulation of ciprofloxacin microparticulates in poloxamer (OTO-201) administered during tympanostomy tube placement in children. Methods: Double-blind, randomized, prospective, placebo- and sham-controlled, multicenter Phase 1b trial in children (6 months to 12 years) with bilateral middle ear effusion requiring tympanostomy tube placement. ... περισσότερα »
Subglottic Basal Cell Adenocarcinoma
Subglottic Basal Cell Adenocarcinoma: Objectives: To discuss the presentation and management of a rare neoplasm in a previously unreported laryngeal subsite. Methods: Case report and literature review. Results: An 89-year-old woman presented with a subglottic mass, biopsy of which was consistent with basal cell adenocarcinoma. She was successfully treated with surgical intervention and remains disease free 29 months postoperatively. Conclusions: Basal cell adenocarcinoma is a rare salivary gland tumor, the laryngeal variant of which is even scarcer. Herein we describe the presen... περισσότερα »
Tracheal and Crico-Tracheal Resection and Anastomosis for Malignancies Involving the Thyroid Gland and the Airway
Tracheal and Crico-Tracheal Resection and Anastomosis for Malignancies Involving the Thyroid Gland and the Airway: Objectives: To evaluate outcomes in different malignancies involving the thyroid and infiltrating the airway submitted to tracheal (TRA) or crico-tracheal resection and anastomosis (CTRA). Methods: Retrospective charts review of 27 patients affected by thyroid malignancies involving the airway treated by TRA/CTRA in a single academic institution. Kaplan-Meier curves were used to evaluate the overall (OS) and disease-specific (DSS) survivals and local (LC) and loco-regi...περισσότερα »
Early Diagnosis and Surgery is Crucial to Survival Outcome in Rhinocerebral Mucormycosis
Managing acute invasive fungal sinusitis KM Dwyhalo, C Donald, A Mendez… - Journal of the American …, 2016 - journals.lww.com *...* PA fellowship in the Department of Otolaryngology/Head & Neck *Surgery*, and Joseph *...* Although acute invasive fungal sinusitis is rare, *early* *detection* can significantly reduce morbidity and *...* tissue may be negative and histopathologic examination is essential for *early* *diagnosis*. *...* Παράθεση Αποθήκευση [PDF] από researchgate.net *Early diagnosis *of cutaneous *mucormycosis *due to Lichtheimia corymbifera after a traffic accident T Tyll... περισσότερα »
Biomechanical and biochemical outcomes of temporomandibular joint disc deformation
Biomechanical and biochemical outcomes of porcine temporomandibular joint disc deformation via Oral Biology Publication date: Available online 7 January 2016 *Source:*Archives of Oral Biology Author(s): Andrea M. Matuska, Stephen Muller, M.Franklin Dolwick, Peter S. McFetridge ObjectiveThe structure-function relationship in the healthy temporomandibular joint (TMJ) disc has been well established, however the changes in dysfunctional joints has yet to be systematically evaluated. Due to the poor understanding of the etiology of temporomandibular disorders (TMDs) this study evaluated na...περισσότερα »
Virologists, start your poliovirus destruction!
I have worked on poliovirus for over thirty-six years, first as a posdoctoral fellow with David Baltimore in 1979, and then in my laboratory at Columbia University. The end of that research commences this year with the destruction of my stocks of polioviruses. from Infection via ola Kala on Inoreader http://ift.tt/1S87YDR via IFTTT
Primarily Assistance Provided by Knowledgeable Packers Movers in Bangalore
Specialized packers along with movers present wide range associated with shifting facilities inside Bangalore. They offer their own conveniences with inexpensive charge and as well having maintaining the standard of solutions. They will assist customers within varieties of shifting similar to ho... from Infection via ola Kala on Inoreader http://ift.tt/1UBHwAm via IFTTT
Salivary gland dysfunction in Non-Insulin Dependent Diabetes Mellitus (NIDDM) and Obese-Insulin Resistance
Is Salivary Gland Function Altered in Noninsulin-Dependent Diabetes Mellitus and Obese-Insulin Resistance? via Oral Biology Publication date: Available online 7 January 2016 *Source:*Archives of Oral Biology Author(s): Jitjiroj Ittichaicharoen, Nipon Chattipakorn, Siriporn C. Chattipakorn Salivary gland dysfunction in several systemic diseases has been shown to decrease the quality of life in patients. In Non-Insulin Dependent Diabetes Mellitus (NIDDM), inadequate salivary gland function has been evidenced to closely associate with this abnormal glycemic control condition. Although se... περισσότερα »
Device Life of Two Generations of Provox Voice Prostheses
Device Life of Two Generations of Provox Voice Prostheses: Background: Tracheoesophageal voice prostheses are invaluable for speech rehabilitation in patients who have received total laryngectomy, but device failure impedes communication and creates psychosocial and financial burdens. This study compares the Provox 2 and Provox Vega voice prostheses on the parameter of device life. Methods: This was a retrospective observational study of 21 patients with 181 device replacements at an academic tertiary care medical center. Disparity in device life and factors that may influence devi... περισσότερα »
Cell adhesion and polarity in squamous cell carcinoma of the lung
Abstract Lung cancer is a deadly disease that can roughly be classified into three histopathological groups: lung adenocarcinomas, lung squamous cell carcinomas (LSCCs), and small cell carcinomas. These types of lung cancer are molecularly, phenotypically and regionally diverse neoplasms, reflecting differences in their cells of origin. LSCCs commonly arise in the airway epithelium of a main or lobar bronchus, which is an important line of defence against the external environment. Furthermore, most LSCCs are characterized histopathologically by the presence of keratinization and/o...περισσότερα »
Otitis Media and Rhinosinusitis With Pathological Features of Immunoglobulin G4-Related Disease
Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Positive Otitis Media and Rhinosinusitis With Pathological Features of Immunoglobulin G4-Related Disease: A Case Report: Background: Immunoglobulin G4-related disease (IgG4-RD) and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) have different clinical and pathological features. However, differentiation between these 2 disorders is sometimes difficult. Objective: To report a case involving a patient with characteristics of both IgG4-RD and AAV. Methods: Case report with literature review. Results: We rep... περισσότερα »
Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Positive Otitis Media and Rhinosinusitis
Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Positive Otitis Media and Rhinosinusitis With Pathological Features of Immunoglobulin G4-Related Disease: A Case Report: Background: Immunoglobulin G4-related disease (IgG4-RD) and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) have different clinical and pathological features. However, differentiation between these 2 disorders is sometimes difficult. Objective: To report a case involving a patient with characteristics of both IgG4-RD and AAV. Methods: Case report with literature review. Results: We rep... περισσότερα »
Higher serum level of myoglobin could predict the more severity and poor outcome for patients with sepsis
Publication date: Available online 8 January 2016 Source:The American Journal of Emergency Medicine Author(s): Liqiong Yao, Zhiwu Liu, Jinhong Zhu, Bin Li, Chen Chai, Yunlin Tian BackgroundThere have been sporadic case reports published focusing on myoglobin and sepsis. However, there are no systematic studies evaluating the correlation between myoglobin level and sepsis. This study investigated… Continue reading Higher serum level of myoglobin could predict the more severity and poor outcome for patients with sepsis
Letter to editor: The effectiveness of bedside point-of-care ultrasonography in the diagnosis and management of metacarpal fractures
Publication date: Available online 8 January 2016 Source:The American Journal of Emergency Medicine Author(s): Harun Yasin Tuzun, Selim Turkkan, Arsen Arsenishvili from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S8cbYg via IFTTT
Efficient gradient calibration based on diffusion MRI
Purpose To propose a method for calibrating gradient systems and correcting gradient nonlinearities based on diffusion MRI measurements. Methods The gradient scaling in x, y, and z were first offset by up to 5% from precalibrated values to simulate a poorly calibrated system. Diffusion MRI data were acquired in a phantom filled with cyclooctane, and… Continue reading Efficient gradient calibration based on diffusion MRI
Scapular Morphology and Forelimb Use during Foraging in Four Sympatric Cercopithecids
Most investigations of primate scapular morphology use differences in locomotion to explain variation; less is known about how scapular geometry covaries with nonlocomotor behavior. We examined forelimb use during foraging in 4 cercopithecids ranging throughout the Ivory Coast’s Tai Forest. During 5-min feeding bouts, we recorded the frequency individuals of Piliocolobus badius, Colobus polykomos, Cercocebus… Continue reading Scapular Morphology and Forelimb Use during Foraging in Four Sympatric Cercopithecids
How staging of thin melanoma is changed after the introduction of TNM 7th edition: a population-based analysis
Abstract Introduction In 2009, the American Joint Committee on Cancer (AJCC) incorporated the tumor mitotic rate in the melanoma pathological TNM staging system. To investigate the effect of this change on the pT1 substaging of primary cutaneous melanomas, we reclassified the cases collected by a cancer registry according to the 6th and the 7th editions… Continue reading How staging of thin melanoma is changed after the introduction of TNM 7th edition: a population-based analysis
Comparison of nine prognostic scores in patients with brain metastases of breast cancer receiving radiotherapy of the brain
Abstract Purpose Several prognostic indices (PI) have been developed to stratify patients with brain metastases in groups with good or bad prognosis. The aim of our study was to compare nine prognostic scores for patients with brain metastases (BM) of breast cancer receiving radiotherapy. Methods The clinical data of 139 breast cancer patients with BM… Continue reading Comparison of nine prognostic scores in patients with brain metastases of breast cancer receiving radiotherapy of the brain
Risk factors for outcome in refractory acute myeloid leukemia patients treated with a combination of fludarabine, cytarabine, and amsacrine followed by a reduced-intensity conditioning and allogeneic stem cell transplantation
Abstract Introduction Hematopoietic stem cell transplantation (HCT) is considered a standard treatment for high-risk acute myeloid leukemia (AML) in first or second complete remission (CR). Unfortunately, not all patients achieve complete remission prior to HCT. We sought to establish predictive factors for survival after HCT for refractory AML after FLAMSA-RIC. Patients and methods We analyzed… Continue reading Risk factors for outcome in refractory acute myeloid leukemia patients treated with a combination of fludarabine, cytarabine, and amsacrine followed by a reduced-intensity c... περισσότερα »
Drastic morphological and molecular differences between lymph node micrometastatic tumors and macrometastatic tumors of lung adenocarcinoma
Abstract Purpose The expansion of micrometastatic tumors to macrometastatic ones is thought to be tightly regulated by several microenvironmental factors. The aim of this study was to elucidate the morphological and phenotypical differences between micrometastatic and macrometastatic tumors. Method We first examined the morphological characteristics of 66 lymph node (LN) micrometastatic tumors (less than 2… Continue reading Drastic morphological and molecular differences between lymph node micrometastatic tumors and macrometastatic tumors of lung adenocarcinoma
Impact of functional germline variants and a deletion polymorphism in APOBEC3A and APOBEC3B on breast cancer risk and survival in a Swedish study population
Abstract Purpose The C → T mutation signature caused by APOBEC family members contributes to the development of breast cancer (BC). Also overexpression of APOBEC3B and a ~29.5-kb deletion polymorphism between APOBEC3A and APOBEC3B have been associated with increased BC risk. Methods We investigated in a population-based study, with 782 Swedish BC cases and 1559… Continue reading Impact of functional germline variants and a deletion polymorphism in APOBEC3A and APOBEC3B on breast cancer risk and survival in a Swedish study population
Long-term follow-up of the AML97 study for patients aged 60 years and above with acute myeloid leukaemia: a study of the East German Haematology and Oncology Study Group (OSHO)
Abstract Introduction Treatment of patients (pts) with acute myelogenous leukaemia (AML) above 60 years remains a challenge. We report long-term follow-up of the AML97 study, where pts were registered at diagnosis and received treatment dependent on their comorbidities: dose-intense cytarabine (AraC) and anthracycline in the curative arm, and low-dose chemotherapy in the palliative arm or… Continue reading Long-term follow-up of the AML97 study for patients aged 60 years and above with acute myeloid leukaemia: a study of the East German Haematology and Oncology Study Group (OSHO)
Virologists, start your poliovirus destruction!
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 27 δευτερόλεπτα
I have worked on poliovirus for over thirty-six years, first as a posdoctoral fellow with David Baltimore in 1979, and then in my laboratory at Columbia University. The end of that research commences this year with the destruction of my stocks of polioviruses. from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1S87YDR via IFTTT Medicine by […]
Primarily Assistance Provided by Knowledgeable Packers Movers in Bangalore
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 27 δευτερόλεπτα
Specialized packers along with movers present wide range associated with shifting facilities inside Bangalore. They offer their own conveniences with inexpensive charge and as well having maintaining the standard of solutions. They will assist customers within varieties of shifting similar to ho… from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1UBHwAm via IFTTT Medicine by Alexandros […]
Clinical outcomes of melanoma brain metastases treated with stereotactic radiation and anti-PD-1 therapy
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 27 δευτερόλεπτα
Anti-PD-1 therapy has demonstrated significant activity in metastatic melanoma. We report good local control and minimal neurotoxicity with the combination of nivolumab and stereotactic radiation in the management of melanoma brain metastases. Overall survival and distant brain metastases control appear improved. from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1S881zA via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos […]
Changes in Tumor Expression of HER2 and Hormone Receptors Status after Neoadjuvant Chemotherapy in 21,755 Patients from the Japanese Breast Cancer Registry
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 27 δευτερόλεπτα
We confirmed that loss of HER2-positive status can occur after neoadjuvant treatment in patients with primary HER2-positive breast cancer. Our data strongly support the need for retest ER, PgR, HER2 of surgical sample after neoadjuvant therapy in order to accurately determine appropriate use of targeted therapy. from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1K22lzo via […]
Impact of Robotic Platforms on Surgical Approach and Costs in the Management of Morbidly Obese Patients with Newly Diagnosed Uterine Cancer
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 27 δευτερόλεπτα
Abstract Background Minimally invasive surgery (MIS) is associated with decreased complication rates, length of hospital stay, and cost compared with laparotomy. Robotic-assisted surgery—a method of laparoscopy—addresses many of the limitations of standard laparoscopic instrumentation, thus leading to increased rates of MIS. We sought to assess the impact of robotics on the rates and costs of […]
Oncologic Risk Stratification Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Appendiceal Carcinomatosis
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 28 δευτερόλεπτα
Abstract Introduction Patients with peritoneal carcinomatosis (PC) of appendiceal origin demonstrate variable oncologic outcomes, despite aggressive cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS–HIPEC). We sought to devise a prognostic risk stratification system for oncologic outcomes following CRS–HIPEC. Methods A total of 197 patients undergoing CRS–HIPEC for the treatment of appendiceal PC were reviewed from a […]
Melanoma Patient-Reported Quality of Life Outcomes Following Sentinel Lymph Node Biopsy, Completion Lymphadenectomy, and Adjuvant Interferon: Results from the Sunbelt Melanoma Trial
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 28 δευτερόλεπτα
Abstract Background Quality of life (QOL) and physical condition (PC) outcomes after sentinel lymph node biopsy (SLNB), completion lymph node dissection (CLND), and adjuvant therapy with interferon alfa-2b (IFN) were evaluated in this study. Methods Self-reported QOL and PC scores were evaluated in patients enrolled in a prospective, multicenter, randomized, clinical trial evaluating adjuvant IFN. […]
Molecular aging of the mammalian vestibular system.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 28 δευτερόλεπτα
Molecular aging of the mammalian vestibular system. Ageing Res Rev. 2015 Dec 28; Authors: Brosel S, Laub C, Averdam A, Bender A, Elstner M Abstract Dizziness and imbalance frequently affect the elderly and contribute to falls and frailty. In many geriatric patients, clinical testing uncovers a dysfunction of the vestibular system, but no specific etiology […]
Molecular aging of the mammalian vestibular system.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 28 δευτερόλεπτα
Molecular aging of the mammalian vestibular system. Ageing Res Rev. 2015 Dec 28; Authors: Brosel S, Laub C, Averdam A, Bender A, Elstner M Abstract Dizziness and imbalance frequently affect the elderly and contribute to falls and frailty. In many geriatric patients, clinical testing uncovers a dysfunction of the vestibular system, but no specific etiology […]
Return to Sports and Physical Activity After Total and Unicondylar Knee Arthroplasty: A Systematic Review and Meta-Analysis
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 28 δευτερόλεπτα
Abstract Background People today are living longer and want to remain active. While obesity is becoming an epidemic, the number of patients suffering from osteoarthritis (OA) is expected to grow exponentially in the coming decades. Patients with OA of the knee are progressively being restricted in their activities. Since a knee arthroplasty (KA) is a […]
Data supporting the structural and functional characterization of Thrombin-Activatable Fibrinolysis Inhibitor in breast cancer.
*Data supporting the structural and functional characterization of Thrombin-Activatable Fibrinolysis Inhibitor in breast cancer.* Data Brief. 2015 Dec;5:981-9 Authors: Fawzy MS, Toraih EA Abstract The data in this paper is related to the research article entitled "Thrombin-activatable fibrinolysis inhibitor Thr325Ile polymorphism and plasma level in breast cancer: A pilot study" (Fawzy et al., 2015) [1]. Many emerging studies have begun to unravel the pathophysiologic role of the fibrinolytic system in breast cancer (BC) progression (Zorio et al., 2008) [2]. Activation of the fi... περισσότερα »
Author reply.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Author reply.* Can J Ophthalmol. 2015 Oct;50(5):396 Authors: Iordanous Y, Sheidow TG PMID: 26455980 [PubMed - indexed for MEDLINE] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/22PoOev via IFTTT
Intravitreal ranibizumab for treatment of fibrovascular pigment epithelial detachment in age-related macular degeneration.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Intravitreal ranibizumab for treatment of fibrovascular pigment epithelial detachment in age-related macular degeneration.* Can J Ophthalmol. 2015 Oct;50(5):395 Authors: Yolcu U, Tas A, Altun S PMID: 26455979 [PubMed - indexed for MEDLINE] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/22PoOer via IFTTT
Final overall survival and safety analysis of OCEANS, a phase 3 trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent ovarian cancer.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Final overall survival and safety analysis of OCEANS, a phase 3 trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent ovarian cancer.* Gynecol Oncol. 2015 Oct;139(1):10-6 Authors: Aghajanian C, Goff B, Nycum LR, Wang YV, Husain A, Blank SV Abstract OBJECTIVE: OCEANS is a randomized, placebo (PL)-controlled, phase 3 trial evaluating the efficacy and safety of bevacizumab combined with gemcitabine+carboplatin (GC) for patients with platinum-sensitive recurrent ovarian cance...περισσότερα »
Ascites predicts treatment benefit of bevacizumab in front-line therapy of advanced epithelial ovarian, fallopian tube and peritoneal cancers: an NRG Oncology/GOG study.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Ascites predicts treatment benefit of bevacizumab in front-line therapy of advanced epithelial ovarian, fallopian tube and peritoneal cancers: an NRG Oncology/GOG study.* Gynecol Oncol. 2015 Oct;139(1):17-22 Authors: Ferriss JS, Java JJ, Bookman MA, Fleming GF, Monk BJ, Walker JL, Homesley HD, Fowler J, Greer BE, Boente MP, Burger RA Abstract OBJECTIVES: Predictive factors for efficacy of bevacizumab in advanced ovarian cancer have remained elusive. We investigated ascites both as a prognostic factor and as a pre... περισσότερα »
Fine-Needle Diathermy Guided by Angiography.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Fine-Needle Diathermy Guided by Angiography.* Cornea. 2015 Sep;34(9):e29-30 Authors: Romano V, Steger B, Kaye SB PMID: 26203758 [PubMed - indexed for MEDLINE] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/22PoLiS via IFTTT
Comparing the effectiveness and costs of Bevacizumab to Ranibizumab in patients with Diabetic Macular Edema: a randomized clinical trial (the BRDME study).
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Comparing the effectiveness and costs of Bevacizumab to Ranibizumab in patients with Diabetic Macular Edema: a randomized clinical trial (the BRDME study).* BMC Ophthalmol. 2015;15:71 Authors: Schauwvlieghe AM, Dijkman G, Hooymans JM, Verbraak FD, Hoyng CB, Dijkgraaf MG, Van Leeuwen R, Vingerling JR, Moll AC, Schlingemann RO Abstract BACKGROUND: The effectiveness of ranibizumab in the treatment of diabetic macular edema has been proven with large clinical trials. For bevacizumab only tw... περισσότερα »
1-year results of combined half-dose photodynamic therapy and ranibizumab for polypoidal choroidal vasculopathy.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *1-year results of combined half-dose photodynamic therapy and ranibizumab for polypoidal choroidal vasculopathy.* BMC Ophthalmol. 2015;15:66 Authors: Wong IY, Shi X, Gangwani R, Zhao P, Iu LP, Li Q, Ng A, Li X Abstract BACKGROUND: To evaluate the efficacy and safety of half-dose photodynamic therapy (PDT combined with ranibizumab for polypoidal choroidal vasculopathy (PCV). PCV is commonly treated with a combination of anti-vascular endothelial growth factor and standard-dose photodynami...περισσότερα »
Pharmacologic evaluation of ammonium tetrathiomolybdate after intravenous and oral administration to healthy dogs.
Related Articles *Pharmacologic evaluation of ammonium tetrathiomolybdate after intravenous and oral administration to healthy dogs.* Am J Vet Res. 2015 May;76(5):445-53 Authors: Chan CM, Langlois DK, Buchweitz JP, Lehner AF, Olivier NB, Herdt TH, Bailie MB, Schall WD Abstract OBJECTIVE: To evaluate pharmacokinetics of ammonium tetrathiomolybdate (TTM) after IV and oral administration to dogs and effects of TTM administration on trace mineral concentrations. ANIMALS: 8 adult Beagles and Beagle crossbreds (4 sexually intact males and 4 sexually intact females). PROCEDURES: Dogs re...περισσότερα »
Actinometric and Φ-order photodegradation properties of anti-cancer Sunitinib.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Actinometric and Φ-order photodegradation properties of anti-cancer Sunitinib.* J Pharm Biomed Anal. 2015 Jun 10;110:34-41 Authors: Maafi M, Lee LY Abstract The photodegradation reaction of Sunitinib (SUT), occurring via Z-E photoisomerisation, has been evaluated in this study using the recently developed Φ-order kinetics. In ethanol, the forward (Z → E) photoreaction of SUT was invariant with irradiation (its quantum yield, Φ(E-->Z)(λ)(irr) ≈ 0.019) in contrast to the E → Z isomerisation whose Φ(E-->Z)(λ)(irr) ...περισσότερα »
Kidney cancer in 2014: Key advances promise progress for kidney cancer patients.
[image: http:--http://ift.tt/1OfhJKq] Related Articles *Kidney cancer in 2014: Key advances promise progress for kidney cancer patients.* Nat Rev Urol. 2015 Feb;12(2):69-70 Authors: Ito T, Kutikov A PMID: 25600094 [PubMed - indexed for MEDLINE] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1OfhJKu via IFTTT
Utility of 18F-FDG PET/CT in the assessment of lymphoepithelioma-like carcinoma.
*Utility of 18F-FDG PET/CT in the assessment of lymphoepithelioma-like carcinoma.* Nucl Med Commun. 2016 Jan 6; Authors: Chan HY, Tsoi A, Wong MP, Ho JC, Lee EY Abstract Lymphoepithelioma-like carcinoma (LELC) is a rare Epstein-Barr virus (EBV)-related disease, which commonly originates from the lung and is associated with more favourable treatment outcomes compared with other non-LELC thoracic carcinomas. Radiological assessment utilizing fluorine-18 fluorodeoxyglucose PET combined with computed tomography (F-FDG PET/CT) is important for initial disease staging to tailor the tr... περισσότερα »
The role of fluorine-18 fluorodeoxyglucose PET in prognosis evaluation for stem cell transplantation of lymphoma: a systematic review and meta-analysis.
*The role of fluorine-18 fluorodeoxyglucose PET in prognosis evaluation for stem cell transplantation of lymphoma: a systematic review and meta-analysis.* Nucl Med Commun. 2016 Jan 6; Authors: Wang C, Li P, Wu S, Lu J, Liu Q, Luo H, Song S Abstract The role of fluorine-18 fluorodeoxyglucose PET (F-FDG PET) in prognostic evaluation of pre-stem cell transplantation (SCT) and post-SCT is still uncertain. A systematic review and meta-analysis were carried out to detect the prognostic power of F-FDG PET. 'PubMed', EMBASE, and Springer were searched for relevant articles. Subgroup ana...περισσότερα »
Occurrence of typical perfusion defects attributed to jailed or occluded side branch after ramus descendens anterior stenting in a patient cohort referred for 13NH3 myocardial PET/CT.
*Occurrence of typical perfusion defects attributed to jailed or occluded side branch after ramus descendens anterior stenting in a patient cohort referred for 13NH3 myocardial PET/CT.* Nucl Med Commun. 2016 Jan 6; Authors: Kan H, Knol RJ, Lazarenko SV, Wondergem M, Van der Zant FM Abstract AIM: Coronary stenting is frequently accompanied by occlusion or jailing of side branches. This can cause small reversible or persistent perfusion defects on myocardial perfusion single photon emission computed tomography studies, but data from NH3 myocardial perfusion PET/computed tomography ... περισσότερα »
Profiling the Behavior of Distinct Populations of Head and Neck Cancer Stem Cells.
*Profiling the Behavior of Distinct Populations of Head and Neck Cancer Stem Cells.* Cancers (Basel). 2016;8(1) Authors: Almeida LO, Guimarães DM, Squarize CH, Castilho RM Abstract Cancer stem cells (CSCs) are a subpopulation of tumor cells endowed with self-renewal properties and the capacity to dynamically adapt to physiological changes that occur in the tumor microenvironment. CSCs play a central role in resistance to therapy and long-term disease recurrence. Better characterization and understanding of the available in vitro tools to study the biology of CSCs will improve ou... περισσότερα »
Commentary on "The View from Outside".
*Commentary on "The View from Outside".* South Med J. 2016 Jan;109(1):23 Authors: Holt GR PMID: 26741868 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1ORlDPl via IFTTT
Isolation and Localization of Mesenchymal Stem Cells in Human Palatine Tonsil by W5C5 (SUSD2).
*Isolation and Localization of Mesenchymal Stem Cells in Human Palatine Tonsil by W5C5 (SUSD2).* Cell Physiol Biochem. 2016 Jan 8;38(1):83-93 Authors: Lee BJ, Kang DW, Park HY, Song JS, Kim JM, Jang JY, Lee JC, Wang SG, Jung JS, Shin SC Abstract BACKGROUND/AIMS: Although tonsil-mesenchymal stem cells (T-MSCs) have been studied as a new autologous or homologous source of MSCs, research on specific markers of MSCs and localization for purified T-MSC isolation has not yet been reported. This study investigates the expression of W5C5 (SUSD2) in tonsil stromal cells and the colony-fo... περισσότερα »
Association Between HbA1c Level and Hearing Impairment in a Nondiabetic Adult Population.
*Association Between HbA1c Level and Hearing Impairment in a Nondiabetic Adult Population.* Metab Syndr Relat Disord. 2016 Jan 7; Authors: Kang SH, Jung DJ, Cho KH, Park JW, Lee KY, Do JY Abstract BACKGROUND: The aim of this study was to investigate whether glycosylated hemoglobin (HbA1c) level in nondiabetic patients is associated with hearing impairment in the general Korean population. PATIENTS AND METHODS: Data from the Korean National Health and Nutrition Examination Survey 2011-2013 were used in the analyses. Participants were excluded from this study for the following reas... περισσότερα »
POGZ truncating alleles cause syndromic intellectual disability.
*POGZ truncating alleles cause syndromic intellectual disability.* Genome Med. 2016;8(1):3 Authors: White J, Beck CR, Harel T, Posey JE, Jhangiani SN, Tang S, Farwell KD, Powis Z, Mendelsohn NJ, Baker JA, Pollack L, Mason KJ, Wierenga KJ, Arrington DK, Hall M, Psychogios A, Fairbrother L, Walkiewicz M, Person RE, Niu Z, Zhang J, Rosenfeld JA, Muzny DM, Eng C, Beaudet AL, Lupski JR, Boerwinkle E, Gibbs RA, Yang Y, Xia F, Sutton VR Abstract BACKGROUND: Large-scale cohort-based whole exome sequencing of individuals with neurodevelopmental disorders (NDDs) has identified numerous nov... περισσότερα »
Odds are good that risky gambling choices are influenced by a single brain connection
One person's risky bet is another's exciting opportunity.The difference between those outlooks comes down to more than just disposition: It turns out that people with a stronger connection… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1K236IF via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TJlb3w via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RoeDKe via IFTTT
Virologists, start your poliovirus destruction!
I have worked on poliovirus for over thirty-six years, first as a posdoctoral fellow with David Baltimore in 1979, and then in my laboratory at Columbia University. The end of that research commences this year with the destruction of my stocks of polioviruses. from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1S87YDR via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OEhZpZ via IF...περισσότερα »
Extensive Metoidioplasty as a Technique Capable of Creating a Compatible Analogue to a Natural Penis in Female Transsexuals
Abstract Objective To introduce the operative technique of "extensive metoidioplasty" (EM) in female transsexual surgery, for achieving an effective reconstruction of a male-appearing, normally functioning, fully sensate and erectile external genitalia. Patients and Methods Ten female transsexuals (46 xx karyotype) between the ages of 20 and 40 years underwent EM as their sex reassignment surgical procedure with the mean operative time of 171 min (45–211, SD 19.55 min) between 2007 and 2014 in a general hospital in Tehran, Iran. Subjects were closely followed for the mean time of... περισσότερα »
Primarily Assistance Provided by Knowledgeable Packers Movers in Bangalore
Specialized packers along with movers present wide range associated with shifting facilities inside Bangalore. They offer their own conveniences with inexpensive charge and as well having maintaining the standard of solutions. They will assist customers within varieties of shifting similar to ho… from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1UBHwAm via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on ... περισσότερα »
Molecular aging of the mammalian vestibular system.
*Molecular aging of the mammalian vestibular system.* Ageing Res Rev. 2015 Dec 28; Authors: Brosel S, Laub C, Averdam A, Bender A, Elstner M Abstract Dizziness and imbalance frequently affect the elderly and contribute to falls and frailty. In many geriatric patients, clinical testing uncovers a dysfunction of the vestibular system, but no specific etiology can be identified. Neuropathological studies have demonstrated age-related degeneration of peripheral and central vestibular neurons, but the molecular mechanisms are poorly understood. In contrast, recent studies into age-re... περισσότερα »
Molecular aging of the mammalian vestibular system.
*Molecular aging of the mammalian vestibular system.* Ageing Res Rev. 2015 Dec 28; Authors: Brosel S, Laub C, Averdam A, Bender A, Elstner M Abstract Dizziness and imbalance frequently affect the elderly and contribute to falls and frailty. In many geriatric patients, clinical testing uncovers a dysfunction of the vestibular system, but no specific etiology can be identified. Neuropathological studies have demonstrated age-related degeneration of peripheral and central vestibular neurons, but the molecular mechanisms are poorly understood. In contrast, recent studies into age-re... περισσότερα »
A marker placement laser device for improving repeatability in 3D-foot motion analysis
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Eva Kalkum, Stefan van Drongelen, Johannes Mussler, Sebastian I. Wolf, Benita Kuni BackgroundIn 3D gait analysis, the repeated positioning of markers is associated with a high error rate, particularly when using a complex foot model with many markers. Therefore, a marker placement laser device was developed that ensures a reliable repositioning of markers. We report the development and reliability of this device for the foot at different tape conditions.MethodsIn 38 subjects, markers were placed at the foo...περισσότερα »
A marker placement laser device for improving repeatability in 3D-foot motion analysis
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Eva Kalkum, Stefan van Drongelen, Johannes Mussler, Sebastian I. Wolf, Benita Kuni BackgroundIn 3D gait analysis, the repeated positioning of markers is associated with a high error rate, particularly when using a complex foot model with many markers. Therefore, a marker placement laser device was developed that ensures a reliable repositioning of markers. We report the development and reliability of this device for the foot at different tape conditions.MethodsIn 38 subjects, markers were placed at the foo...περισσότερα »
A marker placement laser device for improving repeatability in 3D-foot motion analysis
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Eva Kalkum, Stefan van Drongelen, Johannes Mussler, Sebastian I. Wolf, Benita Kuni BackgroundIn 3D gait analysis, the repeated positioning of markers is associated with a high error rate, particularly when using a complex foot model with many markers. Therefore, a marker placement laser device was developed that ensures a reliable repositioning of markers. We report the development and reliability of this device for the foot at different tape conditions.MethodsIn 38 subjects, markers were placed at the foo...περισσότερα »
POGZ truncating alleles cause syndromic intellectual disability.
*POGZ truncating alleles cause syndromic intellectual disability.* Genome Med. 2016;8(1):3 Authors: White J, Beck CR, Harel T, Posey JE, Jhangiani SN, Tang S, Farwell KD, Powis Z, Mendelsohn NJ, Baker JA, Pollack L, Mason KJ, Wierenga KJ, Arrington DK, Hall M, Psychogios A, Fairbrother L, Walkiewicz M, Person RE, Niu Z, Zhang J, Rosenfeld JA, Muzny DM, Eng C, Beaudet AL, Lupski JR, Boerwinkle E, Gibbs RA, Yang Y, Xia F, Sutton VR Abstract BACKGROUND: Large-scale cohort-based whole exome sequencing of individuals with neurodevelopmental disorders (NDDs) has identified numerous nov... περισσότερα »
Odds are good that risky gambling choices are influenced by a single brain connection
One person's risky bet is another's exciting opportunity.The difference between those outlooks comes down to more than just disposition: It turns out that people with a stronger connection… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1K236IF via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TJlb3w via IFTTT
Virologists, start your poliovirus destruction!
I have worked on poliovirus for over thirty-six years, first as a posdoctoral fellow with David Baltimore in 1979, and then in my laboratory at Columbia University. The end of that research commences this year with the destruction of my stocks of polioviruses. from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1S87YDR via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OEhZpZ via IFTTT
Extensive Metoidioplasty as a Technique Capable of Creating a Compatible Analogue to a Natural Penis in Female Transsexuals
Abstract Objective To introduce the operative technique of "extensive metoidioplasty" (EM) in female transsexual surgery, for achieving an effective reconstruction of a male-appearing, normally functioning, fully sensate and erectile external genitalia. Patients and Methods Ten female transsexuals (46 xx karyotype) between the ages of 20 and 40 years underwent EM as their sex reassignment surgical procedure with the mean operative time of 171 min (45–211, SD 19.55 min) between 2007 and 2014 in a general hospital in Tehran, Iran. Subjects were closely followed for the mean time of... περισσότερα »
Primarily Assistance Provided by Knowledgeable Packers Movers in Bangalore
Specialized packers along with movers present wide range associated with shifting facilities inside Bangalore. They offer their own conveniences with inexpensive charge and as well having maintaining the standard of solutions. They will assist customers within varieties of shifting similar to ho… from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1UBHwAm via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on ... περισσότερα »
Evaluation of individually body weight adapted contrast media injection in coronary CT-angiography
Publication date: Available online 7 January 2016 *Source:*European Journal of Radiology Author(s): Casper Mihl, Madeleine Kok, Sibel Altintas, Bas L.J.H. Kietselaer, Jakub Turek, Joachim E. Wildberger, Marco Das ObjectivesContrast media (CM) injection protocols should be customized to the individual patient. Aim of this study was to determine if software tailored CM injections result in diagnostic enhancement of the coronary arteries in computed tomography angiography (CTA) and if attenuation values were comparable between different weight categories.Materials and Methods265 consec...περισσότερα »
Activity-dependent regulation of calcium and ribosomes in the chick cochlear nucleus
[image: alertIcon.gif] Publication date: 1 March 2016 *Source:*Neuroscience, Volume 316 Author(s): C.L. Call, R.L. Hyson Cochlea removal results in the death of 20–30% of neurons in the chick cochlear nucleus, nucleus magnocellularis (NM). Two potentially cytotoxic events, a dramatic rise in intracellular calcium concentration ([Ca2+]i) and a decline in the integrity of ribosomes are observed within 1h of deafferentation. Glutamatergic input from the auditory nerve has been shown to preserve NM neuron health by activating metabotropic glutamate receptors (mGluRs), maintaining both ... περισσότερα »
Clinical outcomes of melanoma brain metastases treated with stereotactic radiation and anti-PD-1 therapy
Anti-PD-1 therapy has demonstrated significant activity in metastatic melanoma. We report good local control and minimal neurotoxicity with the combination of nivolumab and stereotactic radiation in the management of melanoma brain metastases. Overall survival and distant brain metastases control appear improved. from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1S881zA via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G... περισσότερα »
The impact of residual angulation on patient reported functional outcome scores after non-operative treatment for humeral shaft fractures
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgxE7 via IFTTT
Influenza in the emergency department: vaccination, diagnosis, and treatment: clinical practice paper approved by American Academy of Emergency Medicine Clinical Guidelines Committee
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgvMg via IFTTT
Cost-effectiveness analysis of follow-up strategies for thunderclap headache patients with negative non-contrast CT
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgvvM via IFTTT
The long-term outcome after treatment for patients with tibial fracture treated with intramedullary nailing is not influenced by time of day of surgery and surgeon experience
European Journal of Trauma and Emergency Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TJjuDc via IFTTT
Children with arachnoid cysts who sustain blunt head trauma: injury mechanisms and outcomes
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgxnn via IFTTT
A prospective evaluation of shared-decision making regarding analgesics selection for older emergency department patients with acute musculoskeletal pain
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TJjwep via IFTTT
Paediatric trauma systems and their impact on the health outcomes of severely injured children: an integrative review
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgx6W via IFTTT
Pulse oximeter plethysmograph estimate of pulsus paradoxus as a measure of acute asthma exacerbation severity and response to treatment
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TJju6f via IFTTT
Priorities of care among older adults in the emergency department: a cross-sectional study
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgwQy via IFTTT
Prospective, randomized, double blind controlled trial comparing vapocoolant spray versus placebo spray in adults undergoing venipuncture
The American Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TJjt2n via IFTTT
Analysis of emergency vascular surgery consults within a tertiary health care system
Journal of Vascular Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TJjtPG via IFTTT
Chest abdominal-focused assessment sonography for trauma during the primary survey in the emergency department: the CA-FAST protocol
European Journal of Trauma and Emergency Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgwQp via IFTTT
Effectiveness of educational interventions to increase primary care follow-up for adults seen in the emergency department for acute asthma: a systematic review and meta-analysis
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TJjtzl via IFTTT
Longitudinal Trends in U.S. Drug Shortages for Medications Used in Emergency Departments (2001–2014)
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgwA6 via IFTTT
Safe zone for the superficial femoral artery demonstrated on computed tomography angiography
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgurP via IFTTT
The posterior intrafocal pin improves sagittal alignment in Gartland type III paediatric supracondylar humeral fractures
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TJjqDF via IFTTT
Prevention and management of obinutuzumab-associated toxicities: Australian experience
International Journal of Nursing Practice from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgwzV via IFTTT
Quantification of diabetes consultations by the main primary health care nurse groups in Auckland, New Zealand
Brief Report Barbara Daly, Bruce Arroll, Nicolette Sheridan, Timothy Kenealy, Robert Scragg Primary Health Care Research Development, FirstView Article(s), 6 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Zadcy4 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OEi1Oy via IFTTT
Synthetic Bax-Anti Bcl 2 combination module actuated by super artificial hTERT promoter selectively inhibits malignant phenotypes of bladder cancer
Abstract Background The synthetic biology technology which enhances the specificity and efficacy of treatment is a novel try in biomedical therapy during recent years. A high frequency of somatic mutations was shown in the human telomerase reverse transcriptase (hTERT) promoter in bladder cancer, indicating that a mutational hTERT promoter might be a tumor-specific element for bladder cancer therapy. In our study, we aimed to construct a synthetic combination module driven by a super artificial hTERT promoter and to investigate its influence on the malignant phenotypes of bladder ... περισσότερα »
Changes in Tumor Expression of HER2 and Hormone Receptors Status after Neoadjuvant Chemotherapy in 21,755 Patients from the Japanese Breast Cancer Registry
We confirmed that loss of HER2-positive status can occur after neoadjuvant treatment in patients with primary HER2-positive breast cancer. Our data strongly support the need for retest ER, PgR, HER2 of surgical sample after neoadjuvant therapy in order to accurately determine appropriate use of targeted therapy. from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1K22lzo via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.... περισσότερα »
Impact of Robotic Platforms on Surgical Approach and Costs in the Management of Morbidly Obese Patients with Newly Diagnosed Uterine Cancer
Abstract Background Minimally invasive surgery (MIS) is associated with decreased complication rates, length of hospital stay, and cost compared with laparotomy. Robotic-assisted surgery—a method of laparoscopy—addresses many of the limitations of standard laparoscopic instrumentation, thus leading to increased rates of MIS. We sought to assess the impact of robotics on the rates and costs of surgical approaches in morbidly obese patients with uterine cancer. Methods Patients who underwent primary surgery at our institution for uterine cancer from 1993 to 2012 with a BMI ≥40 mg/m...περισσότερα »
Imaging of tarsal navicular stress injury with a focus on MRI: A pictorial essay
Summary Predominantly diagnosed in athletes, stress fracture of the tarsal navicular is becoming increasingly recognised by clinicians as a cause of midfoot pain. Delayed diagnosis can increase the significant morbidity associated with this condition. Consequently the role of MRI is increasing, given the potential to identify a stress reaction in the navicular prior to the development of a discrete stress fracture. It is necessary for radiologists to be familiar with the typical and atypical appearances of this important condition. from #Medicine-SfakianakisAlexandros via o.lakala... περισσότερα »
Screen-detected breast carcinoma with macroscopic dystrophic calcification: A pictorial essay with radiolological pathological correlation
Summary Breast calcifications are among the most common abnormal radiographic findings detected at screening mammography. This essay illustrates the clinico-pathological features of nine screen-detected breast carcinomas, which had benign-appearing macrocalcifications, as a radiographically dominant presenting feature. We aimed to demonstrate that benign-appearing calcifications within a breast lesion are not diagnostic of a benign process if the other imaging characteristics of the lesion are suspicious of malignancy. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoread... περισσότερα »
Melanoma Patient-Reported Quality of Life Outcomes Following Sentinel Lymph Node Biopsy, Completion Lymphadenectomy, and Adjuvant Interferon: Results from the Sunbelt Melanoma Trial
Abstract Background Quality of life (QOL) and physical condition (PC) outcomes after sentinel lymph node biopsy (SLNB), completion lymph node dissection (CLND), and adjuvant therapy with interferon alfa-2b (IFN) were evaluated in this study. Methods Self-reported QOL and PC scores were evaluated in patients enrolled in a prospective, multicenter, randomized, clinical trial evaluating adjuvant IFN. After SLN biopsy, patients with a positive SLN underwent CLND then were randomized to adjuvant IFN or observation. QOL and PC scores were compared between patients who underwent SLNB alo...περισσότερα »
Data supporting the structural and functional characterization of Thrombin-Activatable Fibrinolysis Inhibitor in breast cancer.
*Data supporting the structural and functional characterization of Thrombin-Activatable Fibrinolysis Inhibitor in breast cancer.* Data Brief. 2015 Dec;5:981-9 Authors: Fawzy MS, Toraih EA Abstract The data in this paper is related to the research article entitled "Thrombin-activatable fibrinolysis inhibitor Thr325Ile polymorphism and plasma level in breast cancer: A pilot study" (Fawzy et al., 2015) [1]. Many emerging studies have begun to unravel the pathophysiologic role of the fibrinolytic system in breast cancer (BC) progression (Zorio et al., 2008) [2]. Activation of the fi... περισσότερα »
Author reply.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Author reply.* Can J Ophthalmol. 2015 Oct;50(5):396 Authors: Iordanous Y, Sheidow TG PMID: 26455980 [PubMed - indexed for MEDLINE] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/22PoOev via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PNwTJA via IFTTT
Intravitreal ranibizumab for treatment of fibrovascular pigment epithelial detachment in age-related macular degeneration.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Intravitreal ranibizumab for treatment of fibrovascular pigment epithelial detachment in age-related macular degeneration.* Can J Ophthalmol. 2015 Oct;50(5):395 Authors: Yolcu U, Tas A, Altun S PMID: 26455979 [PubMed - indexed for MEDLINE] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/22PoOer via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ORuyAl via IFTTT
Final overall survival and safety analysis of OCEANS, a phase 3 trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent ovarian cancer.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Final overall survival and safety analysis of OCEANS, a phase 3 trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent ovarian cancer.* Gynecol Oncol. 2015 Oct;139(1):10-6 Authors: Aghajanian C, Goff B, Nycum LR, Wang YV, Husain A, Blank SV Abstract OBJECTIVE: OCEANS is a randomized, placebo (PL)-controlled, phase 3 trial evaluating the efficacy and safety of bevacizumab combined with gemcitabine+carboplatin (GC) for patients with platinum-sensitive recurrent ovarian cance...περισσότερα »
Ascites predicts treatment benefit of bevacizumab in front-line therapy of advanced epithelial ovarian, fallopian tube and peritoneal cancers: an NRG Oncology/GOG study.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Ascites predicts treatment benefit of bevacizumab in front-line therapy of advanced epithelial ovarian, fallopian tube and peritoneal cancers: an NRG Oncology/GOG study.* Gynecol Oncol. 2015 Oct;139(1):17-22 Authors: Ferriss JS, Java JJ, Bookman MA, Fleming GF, Monk BJ, Walker JL, Homesley HD, Fowler J, Greer BE, Boente MP, Burger RA Abstract OBJECTIVES: Predictive factors for efficacy of bevacizumab in advanced ovarian cancer have remained elusive. We investigated ascites both as a prognostic factor and as a pre... περισσότερα »
Fine-Needle Diathermy Guided by Angiography.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Fine-Needle Diathermy Guided by Angiography.* Cornea. 2015 Sep;34(9):e29-30 Authors: Romano V, Steger B, Kaye SB PMID: 26203758 [PubMed - indexed for MEDLINE] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/22PoLiS via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ORuyAh via IFTTT
Comparing the effectiveness and costs of Bevacizumab to Ranibizumab in patients with Diabetic Macular Edema: a randomized clinical trial (the BRDME study).
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Comparing the effectiveness and costs of Bevacizumab to Ranibizumab in patients with Diabetic Macular Edema: a randomized clinical trial (the BRDME study).* BMC Ophthalmol. 2015;15:71 Authors: Schauwvlieghe AM, Dijkman G, Hooymans JM, Verbraak FD, Hoyng CB, Dijkgraaf MG, Van Leeuwen R, Vingerling JR, Moll AC, Schlingemann RO Abstract BACKGROUND: The effectiveness of ranibizumab in the treatment of diabetic macular edema has been proven with large clinical trials. For bevacizumab only tw... περισσότερα »
1-year results of combined half-dose photodynamic therapy and ranibizumab for polypoidal choroidal vasculopathy.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *1-year results of combined half-dose photodynamic therapy and ranibizumab for polypoidal choroidal vasculopathy.* BMC Ophthalmol. 2015;15:66 Authors: Wong IY, Shi X, Gangwani R, Zhao P, Iu LP, Li Q, Ng A, Li X Abstract BACKGROUND: To evaluate the efficacy and safety of half-dose photodynamic therapy (PDT combined with ranibizumab for polypoidal choroidal vasculopathy (PCV). PCV is commonly treated with a combination of anti-vascular endothelial growth factor and standard-dose photodynami...περισσότερα »
Pharmacologic evaluation of ammonium tetrathiomolybdate after intravenous and oral administration to healthy dogs.
Related Articles *Pharmacologic evaluation of ammonium tetrathiomolybdate after intravenous and oral administration to healthy dogs.* Am J Vet Res. 2015 May;76(5):445-53 Authors: Chan CM, Langlois DK, Buchweitz JP, Lehner AF, Olivier NB, Herdt TH, Bailie MB, Schall WD Abstract OBJECTIVE: To evaluate pharmacokinetics of ammonium tetrathiomolybdate (TTM) after IV and oral administration to dogs and effects of TTM administration on trace mineral concentrations. ANIMALS: 8 adult Beagles and Beagle crossbreds (4 sexually intact males and 4 sexually intact females). PROCEDURES: Dogs re...περισσότερα »
Actinometric and Φ-order photodegradation properties of anti-cancer Sunitinib.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Actinometric and Φ-order photodegradation properties of anti-cancer Sunitinib.* J Pharm Biomed Anal. 2015 Jun 10;110:34-41 Authors: Maafi M, Lee LY Abstract The photodegradation reaction of Sunitinib (SUT), occurring via Z-E photoisomerisation, has been evaluated in this study using the recently developed Φ-order kinetics. In ethanol, the forward (Z → E) photoreaction of SUT was invariant with irradiation (its quantum yield, Φ(E-->Z)(λ)(irr) ≈ 0.019) in contrast to the E → Z isomerisation whose Φ(E-->Z)(λ)(irr) ...περισσότερα »
Kidney cancer in 2014: Key advances promise progress for kidney cancer patients.
[image: http:--http://ift.tt/1OfhJKq] Related Articles *Kidney cancer in 2014: Key advances promise progress for kidney cancer patients.* Nat Rev Urol. 2015 Feb;12(2):69-70 Authors: Ito T, Kutikov A PMID: 25600094 [PubMed - indexed for MEDLINE] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1OfhJKu via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ORuws4 via IFTTT
Utility of 18F-FDG PET/CT in the assessment of lymphoepithelioma-like carcinoma.
*Utility of 18F-FDG PET/CT in the assessment of lymphoepithelioma-like carcinoma.* Nucl Med Commun. 2016 Jan 6; Authors: Chan HY, Tsoi A, Wong MP, Ho JC, Lee EY Abstract Lymphoepithelioma-like carcinoma (LELC) is a rare Epstein-Barr virus (EBV)-related disease, which commonly originates from the lung and is associated with more favourable treatment outcomes compared with other non-LELC thoracic carcinomas. Radiological assessment utilizing fluorine-18 fluorodeoxyglucose PET combined with computed tomography (F-FDG PET/CT) is important for initial disease staging to tailor the tr... περισσότερα »
The role of fluorine-18 fluorodeoxyglucose PET in prognosis evaluation for stem cell transplantation of lymphoma: a systematic review and meta-analysis.
*The role of fluorine-18 fluorodeoxyglucose PET in prognosis evaluation for stem cell transplantation of lymphoma: a systematic review and meta-analysis.* Nucl Med Commun. 2016 Jan 6; Authors: Wang C, Li P, Wu S, Lu J, Liu Q, Luo H, Song S Abstract The role of fluorine-18 fluorodeoxyglucose PET (F-FDG PET) in prognostic evaluation of pre-stem cell transplantation (SCT) and post-SCT is still uncertain. A systematic review and meta-analysis were carried out to detect the prognostic power of F-FDG PET. 'PubMed', EMBASE, and Springer were searched for relevant articles. Subgroup ana...περισσότερα »
Occurrence of typical perfusion defects attributed to jailed or occluded side branch after ramus descendens anterior stenting in a patient cohort referred for 13NH3 myocardial PET/CT.
*Occurrence of typical perfusion defects attributed to jailed or occluded side branch after ramus descendens anterior stenting in a patient cohort referred for 13NH3 myocardial PET/CT.* Nucl Med Commun. 2016 Jan 6; Authors: Kan H, Knol RJ, Lazarenko SV, Wondergem M, Van der Zant FM Abstract AIM: Coronary stenting is frequently accompanied by occlusion or jailing of side branches. This can cause small reversible or persistent perfusion defects on myocardial perfusion single photon emission computed tomography studies, but data from NH3 myocardial perfusion PET/computed tomography ... περισσότερα »
Imaging of tarsal navicular stress injury with a focus on MRI: A pictorial essay
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 56 δευτερόλεπτα
Summary Predominantly diagnosed in athletes, stress fracture of the tarsal navicular is becoming increasingly recognised by clinicians as a cause of midfoot pain. Delayed diagnosis can increase the significant morbidity associated with this condition. Consequently the role of MRI is increasing, given the potential to identify a stress reaction in the navicular prior to the […]
Screen-detected breast carcinoma with macroscopic dystrophic calcification: A pictorial essay with radiolological pathological correlation
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 56 δευτερόλεπτα
Summary Breast calcifications are among the most common abnormal radiographic findings detected at screening mammography. This essay illustrates the clinico-pathological features of nine screen-detected breast carcinomas, which had benign-appearing macrocalcifications, as a radiographically dominant presenting feature. We aimed to demonstrate that benign-appearing calcifications within a breast lesion are not diagnostic of a benign process if […]
BDNF Serum Levels with Respect to Multidimensional Assessment in Amyotrophic Lateral Sclerosis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 56 δευτερόλεπτα
Background: The clinical presentation of amyotrophic lateral sclerosis (ALS) is characterized by high heterogeneity, the greatest part of which still remains unexplained. Objective: To assess serum levels of brain-derived neurotrophic factor (BDNF) in ALS patients, implementing a multidimensional characterization focused on four a priori chosen elements of phenotypic variability: ALS bulbar/spinal subtype, cognitive impairment, mood […]
Bacterial influence on consolidation of bone grafts in maxillary sinus elevation
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 56 δευτερόλεπτα
Abstract Objectives The aim of this study was to identify microorganisms present on the maxillary sinus floor at the moment of sinus elevation surgery and, using tomography, to investigate the repercussions these might have for regenerated bone 9 months after the procedure. Materials and methods 174 patients (90 women and 84 men) with a mean […]
Serum S100A8 and S100A9 Enhance Innate Immune Responses in the Pathogenesis of Baker’s Asthma
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 56 δευτερόλεπτα
Background: S100A8 and S100A9 can be produced by lipopolysaccharide-stimulated granulocytes and provoke an innate immune-mediated airway inflammation. Involvement of S100A8 and S100A9 has been implicated in asthma. To further understand the role of S100A8 and S100A9 during innate immune responses in baker’s asthma, we investigated the associations of serum S100A8 and S100A9 with exposure to […]
Return to Sports and Physical Activity After Total and Unicondylar Knee Arthroplasty: A Systematic Review and Meta-Analysis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 56 δευτερόλεπτα
Abstract Background People today are living longer and want to remain active. While obesity is becoming an epidemic, the number of patients suffering from osteoarthritis (OA) is expected to grow exponentially in the coming decades. Patients with OA of the knee are progressively being restricted in their activities. Since a knee arthroplasty (KA) is a […]
Massage and Performance Recovery: A Meta-Analytical Review
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 56 δευτερόλεπτα
Abstract Background Post-exercise massage is one of the most frequently applied interventions to enhance recovery of athletes. However, evidence to support the efficacy of massage for performance recovery is scarce. Moreover, it has not yet been concluded under which conditions massage is effective. Objective The objective of this study was to perform a systematic review […]
Development of an experimental model of neurocysticercosis-induced hydrocephalus. Pilot study
ABSTRACT PURPOSE: To develop an experimental model of neurocysticercosis-induced hydrocephalus METHODS: There were used 17 rats. Ten animals were inoculated with Taenia crassiceps cysts into the subarachnoid. Five animals were injected with 0.1ml of 25% kaolin (a standard solution for the development of experimental hydrocephalus) and two animals were injected with saline. Magnetic resonance imaging (MRI) was used to evaluate enlargement of the ventricles after one or three months of inoculation. Volumetric study was used to quantify the ventricle enlargement. RESULTS: Seven of th...περισσότερα »
Experimental models of renal dysfunction in female rats. Functional and histological aspects after unilateral nephrectomy or ligation of right renal vein with kidney preservation
ABSTRACT PURPOSE: To compare renal dysfunction after right nephrectomy and ligation of the right renal vein with preservation of kidney. METHODS: Animals' weight, pH, density, protein in urine and histological samples of the kidneys were evaluated. Fifteen female rats (Wistar) were divided into three groups. In the control group, right renal vein dissections were performed. In the second group, the right nephrectomy was performed. In the third group, the right renal vein was ligated and the kidney was preserved. Urine samples were taken before, three and seven days after the proced...περισσότερα »
Acupuncture and pharmacopuncture are as effective as morphine or carprofen for postoperative analgesia in bitches undergoing ovariohysterectomy
ABSTRACT PURPOSE : To investigate the analgesic effect of acupuncture (AP) or micro-dose pharmacopuncture (PA), using carprofen or morphine, in bitches undergoing ovariohysterectomy (OHE). METHODS: Thirty five dogs were randomly assigned to five groups after sedation with acepromazine IM: AP, 0.5 mg.kg-1 of morphine subcutaneously (SC), 4 mg.kg-1 of carprofen SC, and PA with 0.05 mg.kg-1 of morphine or 0.4 mg.kg-1 of carprofen. Anaesthesia was induced with propofol and maintained with isoflurane. Pain was assessed after OHE by a blind observer for 24h, by dynamic visual analogue sc...περισσότερα »
Enhanced cyclooxygenase-2 activity leads to intestinal dysmotility following hemorrhagic shock
ABSTRACT PURPOSE: To test whether hemorrhagic shock (HS) increases the Cyclooxygenase-2 (COX-2) expression in the intestine and whether this enhanced COX-2 expression mediates the intestinal dysmotility after HS. METHODS: Male Wistar rats were randomly divided into HS sham group and HS group. At 180 min following HS establishment, the duodenum samples were harvested to assess the motility function, protein expression of COX-2 and the downstream products of COX-2, prostaglandins. RESULTS: Examination of motility function ex vivo showed that the contractile response to acetylcholine... περισσότερα »
Repair of large incisional hernias. To drain or not to drain. Randomized clinical trial
ABSTRACT PURPOSE: To evaluate the occurrence of seroma and surgical wound infection after surgery. METHODS: A total of 42 individuals with large incisional hernias were subjected toonlay mesh repair. Following the mesh placement, the participants were randomly allocated to two groups. In group 1, closed-suction drains were placed in the subcutaneous tissue, while progressive tension sutures were performed in group 2. The participants were subjected to clinical and ultrasound assessment to detect seroma and surgical wound infection at three time-points after surgery. RESULTS: The o...περισσότερα »
Effects of the Low-Level Laser Therapy (LLLT) in the process of healing diabetic foot ulcers
ABSTRACT PURPOSE: To evaluate the effects of the low-level laser therapy applying Laser on the tissue repair in ulcer carriers due to diabetes. METHODS: Sixteen type II diabetic patients, ulcer carriers in the lower limbs, participated in the research from which eight were in the control group and eight were submitted to the low-level laser therapy with a pulsed wave form, visible ray, wave length of 632.8 nm, 30 mW peak power, (Laser - HTM). The application time was of 80 (4J/cm2) seconds. The application was punctual without contact (approximately 1mm of distance), the pen being ... περισσότερα »
Errata
ABSTRACT PURPOSE: To evaluate the effects of the low-level laser therapy applying Laser on the tissue repair in ulcer carriers due to diabetes. METHODS: Sixteen type II diabetic patients, ulcer carriers in the lower limbs, participated in the research from which eight were in the control group and eight were submitted to the low-level laser therapy with a pulsed wave form, visible ray, wave length of 632.8 nm, 30 mW peak power, (Laser - HTM). The application time was of 80 (4J/cm2) seconds. The application was punctual without contact (approximately 1mm of distance), the pen being ... περισσότερα »
Proton detection and breathing regulation by the retrotrapezoid nucleus
Abstract We discuss recent evidence which suggests that the principal central respiratory chemoreceptors are located within the retrotrapezoid nucleus (RTN) and that RTN neurons are directly sensitive to [H+]. RTN neurons are glutamatergic. *In vitro*, their activation by [H+] requires expression of a proton-activated GPCR (GPR4) and a proton-modulated potassium channel (TASK-2) whose transcripts are undetectable in astrocytes and the rest of the lower brainstem respiratory network. The pH response of RTN neurons is modulated by surrounding astrocytes but genetic deletion of RTN n... περισσότερα »
Nouveautés dans la prise en charge des calculs biliaires à l’UEGW 2015
from #Medicine via ola Kala on Inoreader http://ift.tt/1kQplKY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Has provoking microbiota aggression driven the obesity epidemic?
Alterations in the gut microbiome have increasingly been implicated in driving obesity and its associated diseases, but underlying mechanisms remain poorly defined. Herein, in addition to reviewing the field, we hypothesize that a highly significant causative factor of such inflammatory disease-associated microbiome alterations is a more aggressive microbiota that encroaches upon its host, with components having high potential to activate host pro-inflammatory gene expression in a manner that drives metabolic disease. We further hypothesize that a range of societal changes, inclu... περισσότερα »
Single neuron transcriptome analysis can reveal more than cell type classification
A recent single cell mRNA sequencing study by Dueck et al. compares neuronal transcriptomes to the transcriptomes of adipocytes and cardiomyocytes. Single cell 'omic approaches such as those used by the authors are at the leading edge of molecular and biophysical measurement. Many groups are currently employing single cell sequencing approaches to understand cellular heterogeneity in cancer and during normal development. These single cell approaches also are beginning to address long-standing questions regarding nervous system diversity. Beyond an innate interest in cataloging ce...περισσότερα »
Early gut colonization with Lactobacilli and Staphylococcus in infants: The hygiene hypothesis extended
Journal of Pediatric Gastroenterology and Nutrition from #Medicine via ola Kala on Inoreader http://ift.tt/1OfbrdP Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Clinical care pathways for patients with hepatitis C: Reducing critical barriers to effective treatment
Open Forum Infectious Diseases from #Medicine via ola Kala on Inoreader http://ift.tt/1OfbqXe Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Endoscopic resection for undifferentiated-type early gastric cancer: Immediate endoscopic outcomes and long-term survivals
Digestive Diseases and Sciences from #Medicine via ola Kala on Inoreader http://ift.tt/1PStPh2 Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Profiling the Behavior of Distinct Populations of Head and Neck Cancer Stem Cells.
*Profiling the Behavior of Distinct Populations of Head and Neck Cancer Stem Cells.* Cancers (Basel). 2016;8(1) Authors: Almeida LO, Guimarães DM, Squarize CH, Castilho RM Abstract Cancer stem cells (CSCs) are a subpopulation of tumor cells endowed with self-renewal properties and the capacity to dynamically adapt to physiological changes that occur in the tumor microenvironment. CSCs play a central role in resistance to therapy and long-term disease recurrence. Better characterization and understanding of the available in vitro tools to study the biology of CSCs will improve ou... περισσότερα »
Commentary on "The View from Outside".
*Commentary on "The View from Outside".* South Med J. 2016 Jan;109(1):23 Authors: Holt GR PMID: 26741868 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1ORlDPl via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Ofii79 via IFTTT
Isolation and Localization of Mesenchymal Stem Cells in Human Palatine Tonsil by W5C5 (SUSD2).
*Isolation and Localization of Mesenchymal Stem Cells in Human Palatine Tonsil by W5C5 (SUSD2).* Cell Physiol Biochem. 2016 Jan 8;38(1):83-93 Authors: Lee BJ, Kang DW, Park HY, Song JS, Kim JM, Jang JY, Lee JC, Wang SG, Jung JS, Shin SC Abstract BACKGROUND/AIMS: Although tonsil-mesenchymal stem cells (T-MSCs) have been studied as a new autologous or homologous source of MSCs, research on specific markers of MSCs and localization for purified T-MSC isolation has not yet been reported. This study investigates the expression of W5C5 (SUSD2) in tonsil stromal cells and the colony-fo... περισσότερα »
Association Between HbA1c Level and Hearing Impairment in a Nondiabetic Adult Population.
*Association Between HbA1c Level and Hearing Impairment in a Nondiabetic Adult Population.* Metab Syndr Relat Disord. 2016 Jan 7; Authors: Kang SH, Jung DJ, Cho KH, Park JW, Lee KY, Do JY Abstract BACKGROUND: The aim of this study was to investigate whether glycosylated hemoglobin (HbA1c) level in nondiabetic patients is associated with hearing impairment in the general Korean population. PATIENTS AND METHODS: Data from the Korean National Health and Nutrition Examination Survey 2011-2013 were used in the analyses. Participants were excluded from this study for the following reas... περισσότερα »
The Influence of Nebulized Drugs on Nasal Ciliary Activity.
*The Influence of Nebulized Drugs on Nasal Ciliary Activity.* J Aerosol Med Pulm Drug Deliv. 2016 Jan 7; Authors: Boon M, Jorissen M, Jaspers M, Augustijns P, Vermeulen FL, Proesmans M, De Boeck K Abstract INTRODUCTION: Nebulized drugs are used in the treatment of cystic fibrosis (CF) lung disease, asthma, and COPD, and increasingly also in other chronic lung diseases. Their use in CF is reasonably evidence based, but this is not so for use in other orphan diseases. Potential side effects often have not been studied. Therefore, we evaluated the influence of nebulized drugs on ci...περισσότερα »
An extremely rare case of thyroid malignancy from the non-Alpine region: Angiosarcoma.
*An extremely rare case of thyroid malignancy from the non-Alpine region: Angiosarcoma.* Int J Surg Case Rep. 2015 Dec 23;19:92-96 Authors: Bayır Ö, Yılmazer D, Ersoy R, Akca Y, Saylam G, Han Ü, Özdek A, Çakır B, Korkmaz MH Abstract INTRODUCTION: Thyroid angiosarcoma is a rather rare malignancy featuring a poor prognosis, and which may interfere with other aggressive thyroid tumors; it is usually seen in the Alpine region. CASE PRESENTATION: A 74-year-old male was referred to our center with complaints of progressive neck swelling and dyspnea. He had multiple nodules featuring c...περισσότερα »
The Influence of Nebulized Drugs on Nasal Ciliary Activity.
*The Influence of Nebulized Drugs on Nasal Ciliary Activity.* J Aerosol Med Pulm Drug Deliv. 2016 Jan 7; Authors: Boon M, Jorissen M, Jaspers M, Augustijns P, Vermeulen FL, Proesmans M, De Boeck K Abstract INTRODUCTION: Nebulized drugs are used in the treatment of cystic fibrosis (CF) lung disease, asthma, and COPD, and increasingly also in other chronic lung diseases. Their use in CF is reasonably evidence based, but this is not so for use in other orphan diseases. Potential side effects often have not been studied. Therefore, we evaluated the influence of nebulized drugs on ci...περισσότερα »
An extremely rare case of thyroid malignancy from the non-Alpine region: Angiosarcoma.
*An extremely rare case of thyroid malignancy from the non-Alpine region: Angiosarcoma.* Int J Surg Case Rep. 2015 Dec 23;19:92-96 Authors: Bayır Ö, Yılmazer D, Ersoy R, Akca Y, Saylam G, Han Ü, Özdek A, Çakır B, Korkmaz MH Abstract INTRODUCTION: Thyroid angiosarcoma is a rather rare malignancy featuring a poor prognosis, and which may interfere with other aggressive thyroid tumors; it is usually seen in the Alpine region. CASE PRESENTATION: A 74-year-old male was referred to our center with complaints of progressive neck swelling and dyspnea. He had multiple nodules featuring c...περισσότερα »
[MTA1-specific shRNA inhibits the growth and metastasis of mouse xenograft of laryngeal squamous cell carcinoma].
Related Articles *[MTA1-specific shRNA inhibits the growth and metastasis of mouse xenograft of laryngeal squamous cell carcinoma].* Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2015 Sep;31(9):1194-9 Authors: Liu Z, Zhou J, Wang Z, Bai L Abstract OBJECTIVE: To observe the effect of metastasis-associated gene 1 (MTA1) on the growth and metastasis of laryngeal squamous cell carcinoma in nude mice using RNA interference technology (RNAi). METHODS: Lentiviral vector of short hairpin RNA (shRNA) targeting MTA1 was constructed and packaged to transfect Hep-2 cells. Hep-2 cells transfected with...περισσότερα »
Analysis of the position of the branches of the ulnar nerve in Guyon's canal using high-resolution MRI in positions adopted by cyclists.
*Analysis of the position of the branches of the ulnar nerve in Guyon's canal using high-resolution MRI in positions adopted by cyclists.* Surg Radiol Anat. 2016 Jan 6; Authors: Rauch A, Teixeira PA, Gillet R, Perez M, Clerc-Urmes I, Lombard C, Blum A Abstract PURPOSE: To study variations in the anatomical relationships of the branches of the ulnar nerve in Guyon's canal relative to the hamulus of hamate (HH) in a grip encountered among cyclists. MATERIALS AND METHODS: Forty-seven wrist examinations were performed on a 3-T MRI (soft antenna, 16 channels) in propeller sequence in ...περισσότερα »
A unilateral septal flap based on the anterior ethmoidal artery (Castelnuovo's flap): CT cadaver study.
*A unilateral septal flap based on the anterior ethmoidal artery (Castelnuovo's flap): CT cadaver study.* Surg Radiol Anat. 2016 Jan 6; Authors: Gras-Cabrerizo JR, García-Garrigós E, Ademá-Alcover JM, Sarandeses-Garcia A, Martel-Martin M, Montserrat-Gili JR, Gras-Albert JR, Massegur-Solench H Abstract OBJECTIVE: We describe our experience for repair septal perforation with a septal flap and we analyse the route of the septal branch of the anterior ethmoidal artery (AEA) in the septum area with a radiological anatomy study in order to perform this flap. STUDY DESIGN: We carry out...περισσότερα »
Diplopia: a diagnostic challenge with common and rare etiologies.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Diplopia: a diagnostic challenge with common and rare etiologies.* Am J Case Rep. 2015;16:220-3 Authors: Alves M, Miranda A, Narciso MR, Mieiro L, Fonseca T Abstract BACKGROUND: Diplopia is a symptom with very different etiologies. It may be caused by pathology in the eye, orbit, extraocular muscles, neuromuscular junction, or in the central nervous system. CASE REPORT: Three clinical cases of hospitalization due to isolated diplopia are presented here, illustrating different etiologies. CONCLUSIONS: The present article aims t...περισσότερα »
Cytology findings in pancreatic heterotopia, a potential pitfall for malignancy: a case report and literature review.
[image: http:--http://ift.tt/1RoaGoZ] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Cytology findings in pancreatic heterotopia, a potential pitfall for malignancy: a case report and literature review.* Saudi J Gastroenterol. 2015 Mar-Apr;21(2):116-8 Authors: Raddaoui E, Al-Sharabi A, Almadi MA Abstract Pancreatic heterotopia is a rare congenital disorder occurring at a variety of sites in the gastrointestinal tract. It is rarely symptomatic. Despite advances in diagnostic techniques, it still remains a challenge to the clinician to differentiate it from a neoplasm. Cyt... περισσότερα »
Massive spontaneous intraperitoneal hemorrhage in a young female with chronic immune thrombocytopenic purpura masquerading as ruptured ovarian cyst: successful nonsurgical management of this rare catastrophic event.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Massive spontaneous intraperitoneal hemorrhage in a young female with chronic immune thrombocytopenic purpura masquerading as ruptured ovarian cyst: successful nonsurgical management of this rare catastrophic event.* Pediatr Emerg Care. 2015 Apr;31(4):284-5 Authors: Singh N, Tripathi R, Mala YM, Tyagi S, Jain N Abstract Chronic immune thrombocytopenic purpura has mild bleeding manifestations and severe bleeding requiring hospitalization is rare. We are reporting a case of a 19-year-old girl with chronic immune thr...περισσότερα »
The impact of tree stand falls on a Level 1 trauma center in West Michigan
The American Journal of Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgubj via IFTTT
Comparison of clinical outcomes of posterior C1-C2 temporary fixation without fusion and C1-C2 fusion for fresh odontoid fractures
Neurosurgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1OEgubd via IFTTT
Standardized asthma admission criteria reduce length of stay in a pediatric emergency department
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1K1YKBm via IFTTT
Return to Sports and Physical Activity After Total and Unicondylar Knee Arthroplasty: A Systematic Review and Meta-Analysis
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Abstract Background People today are living longer and want to remain active. While obesity is becoming an epidemic, the number of patients suffering from osteoarthritis (OA) is expected to grow exponentially in the coming decades. Patients with OA of the knee are progressively being restricted in their activities. Since a knee arthroplasty (KA) is a well accepted, cost-effective intervention to relieve pain, restore function and improve health-related quality of life, indications are expanding to younger and more active patients. However, evidence concerning return to sports (RTS)... περισσότερα »
Massage and Performance Recovery: A Meta-Analytical Review
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Abstract Background Post-exercise massage is one of the most frequently applied interventions to enhance recovery of athletes. However, evidence to support the efficacy of massage for performance recovery is scarce. Moreover, it has not yet been concluded under which conditions massage is effective. Objective The objective of this study was to perform a systematic review and meta-analysis of the available literature on massage for performance recovery. Methods We conducted a structured literature search and located 22 randomized controlled trials. These were analysed with respec...περισσότερα »
Muscle Weakness Thresholds for Prediction of Diabetes in Adults
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Abstract Background Despite the known links between weakness and early mortality, what remains to be fully understood is the extent to which strength preservation is associated with protection from cardiometabolic diseases, such as diabetes. Purpose The purposes of this study were to determine the association between muscle strength and diabetes among adults, and to identify age- and sex-specific thresholds of low strength for detection of risk. Methods A population-representative sample of 4066 individuals, aged 20–85 years, was included from the combined 2011–2012 National Heal...περισσότερα »
Effect of temporomandibular disorder therapy on otologic signs and symptoms: a systematic review
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Summary The most common temporomandibular disorders (TMD) signs and symptoms are related to muscle sensitivity through palpation, restricted mouth opening, asymmetric mandibular movements, joint sounds, pain and otologic signs and symptoms. To date, counselling, occlusal splints, exercises, biofeedback and acupuncture are examples of conservative modalities proposed for TMD therapy. The aim of this systematic review was to investigate the effect of these conservative therapies for TMD on otologic signs and symptoms. The authors searched the following electronic databases published ...περισσότερα »
Bacterial influence on consolidation of bone grafts in maxillary sinus elevation
[image: cover.gif?v=1&s=2eb91ab0c0aac4a9489c87d3] Abstract Objectives The aim of this study was to identify microorganisms present on the maxillary sinus floor at the moment of sinus elevation surgery and, using tomography, to investigate the repercussions these might have for regenerated bone 9 months after the procedure. Materials and methods 174 patients (90 women and 84 men) with a mean age of 55.92 years underwent 227 sinus elevations (120 left sinus, 107 right sinus). As the membrane was lifted, a sample of the maxillary sinus floor was collected with a cotton swab, and p...περισσότερα »
Serum S100A8 and S100A9 Enhance Innate Immune Responses in the Pathogenesis of Baker’s Asthma
Background: S100A8 and S100A9 can be produced by lipopolysaccharide-stimulated granulocytes and provoke an innate immune-mediated airway inflammation. Involvement of S100A8 and S100A9 has been implicated in asthma. To further understand the role of S100A8 and S100A9 during innate immune responses in baker’s asthma, we investigated the associations of serum S100A8 and S100A9 with exposure to… Continue reading Serum S100A8 and S100A9 Enhance Innate Immune Responses in the Pathogenesis of Baker’s Asthma
Return to Sports and Physical Activity After Total and Unicondylar Knee Arthroplasty: A Systematic Review and Meta-Analysis
Abstract Background People today are living longer and want to remain active. While obesity is becoming an epidemic, the number of patients suffering from osteoarthritis (OA) is expected to grow exponentially in the coming decades. Patients with OA of the knee are progressively being restricted in their activities. Since a knee arthroplasty (KA) is a… Continue reading Return to Sports and Physical Activity After Total and Unicondylar Knee Arthroplasty: A Systematic Review and Meta-Analysis
Massage and Performance Recovery: A Meta-Analytical Review
Abstract Background Post-exercise massage is one of the most frequently applied interventions to enhance recovery of athletes. However, evidence to support the efficacy of massage for performance recovery is scarce. Moreover, it has not yet been concluded under which conditions massage is effective. Objective The objective of this study was to perform a systematic review… Continue reading Massage and Performance Recovery: A Meta-Analytical Review
Muscle Weakness Thresholds for Prediction of Diabetes in Adults
Abstract Background Despite the known links between weakness and early mortality, what remains to be fully understood is the extent to which strength preservation is associated with protection from cardiometabolic diseases, such as diabetes. Purpose The purposes of this study were to determine the association between muscle strength and diabetes among adults, and to identify… Continue reading Muscle Weakness Thresholds for Prediction of Diabetes in Adults
Resource allocation in an annual herb: Effects of light, mycorrhizal fungi, and defoliation
Publication date: February 2016 Source:Acta Oecologica, Volume 71 Author(s): Ana Aguilar-Chama, Roger Guevara Concurrent interactions and the availability of resources (e.g., light) affect the cost/benefit balance during mutualistic and antagonistic interactions, as well as plant resource allocation patterns. Mycorrhizal interactions and herbivory concur in most plants, where mycorrhizae can enhance the uptake of soil nutrients… Continue reading Resource allocation in an annual herb: Effects of light, mycorrhizal fungi, and defoliation
Ecological Innovation: Biomimicry as a New Way of Thinking and Acting Ecologically
Abstract In this article, we critically reflect on the concept of biomimicry. On the basis of an analysis of the concept of biomimicry in the literature and its philosophical origin, we distinguish between a strong and a weaker concept of biomimicry. The strength of the strong concept of biomimicry is that nature is seen as… Continue reading Ecological Innovation: Biomimicry as a New Way of Thinking and Acting Ecologically
Effect of p38 MAPK inhibitor on temporomandibular joint synovitis induced by occlusal alteration
Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Linhong Jiang, Xuefen Lin, Ping Ji PurposeTo investigate the alteration in rats temporomandibular joint (TMJ) synovial membrane induced by increased occlusal vertical dimension (iOVD) and to find whether p38 mitogen activated protein kinase (MAPK) signaling cascade was involved.MethodsThirty-six rats were randomly divided into three groups: the control+ NS group (served as controls), the iOVD+ NS group and the iOVD+ SB203580 (a potent p38 MAPK inhibitor) group. Morphologic...περισσότερα »
Editorial Board Page
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1MWW1J9 via IFTTT
Modified Mandibular Inferior Border Sagittal Split Osteotomy Reduces Postoperative Risk for Developing Inferior Border Defects
Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Jimoh Olubanwo Agbaje, Bert Gemels, Ahmed S. Salem, Dickson Anumendem, Luc Vrielinck, Constantinus Politis PurposeThe purpose of this study was to evaluate the impact of a modified SSO surgical technique on the incidence of persisting inferior border defects. The secondary aim was to identify risk factors associated with the development of this complication.MethodsThe patient charts and radiographs of 276 consecutive patients, who underwent bilateral SSO performed by a sin... περισσότερα »
Table of Contents
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1n7vcNM via IFTTT
AAOMS Author Disclosure forms
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1MWW1sR via IFTTT
Analysis of Risk Factors for Pneumonia in 482 Patients Undergoing Oral Cancer Surgery With Tracheotomy
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Li Li, Weijun Yuan, Shilei Zhang, Kewei Wang, Hong Ruan PurposeElective tracheostomy is a common procedure used in patients with oral cancer. However, secondary tracheotomy-associated pneumonia (TAP) is an important complication after surgery. This study investigated the risk factors related to postoperative TAP complications in patients with oral cancer.Materials and MethodsA retrospective study was performed from January 2012 to October 2013. Data on patients who had or... περισσότερα »
The AAOMS Informational Campaign – Is it Succeeding?
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): James R. Hupp from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1n7vbJx via IFTTT
Sedation protocol using dexmedetomidine for third molar extraction
Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Dae-Seung Ryu, Deok-Won Lee, Sung Chul Choi, In-Hwan Oh PurposeThe aim of this study is to establish a proper sedative protocol of dexmedetomidine for outpatients.Materials and MethodsThe study is designed to compare patients' pain, satisfaction, adverse events, and sedation depth during the extraction of third molars with sedative protocol of intravenous (IV)(1.0 μg/kg) or intranasal (IN)(1.5 μg/kg) administration of dexmedetomidine. A total of 240 patients were randomized... περισσότερα »
Masthead
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1n7vbJv via IFTTT
Effects of Le Fort I Osteotomy on the Nasopharyngeal Airway—6-Month Follow-Up
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Mohammed Almuzian, Anas Almukhtar, Xiangyang Ju, Ali Al-Hiyali, Philip Benington, Ashraf Ayoub PurposeThe literature discussing the impact of a single Le Fort I osteotomy on nasopharyngeal airways is limited. This study assessed the volumetric changes in the nasopharyngeal airway after a single Le Fort I osteotomy and explored the correlation between these changes and 3-dimensional surgical movements of the upper jaw.Materials and MethodsThis retrospective study was cond... περισσότερα »
Role of Negative-Pressure Wound Therapy in the Management of Submandibular Fistula After Reconstruction for Osteoradionecrosis
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Da-ming Zhang, Zhao-hui Yang, Pei-lin Zhuang, You-yuan Wang, Wei-liang Chen, Bin Zhang PurposeAlthough negative-pressure wound therapy (NPWT) for complicated wounds has been extensively studied, it is rarely used in cases involving a submandibular fistula due to radiation-induced osteoradionecrosis of the mandible. This study aimed to investigate the efficacy of NPWT for submandibular fistulas after reconstruction for osteoradionecrosis.Patients and MethodsNine patients ... περισσότερα »
Facial Trauma Update
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Edward Ellis from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1MWVZ4f via IFTTT
The use of computer-assisted navigation in retrieval of accidentally displaced third molar
Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Yi Guo, Dong-Dong Xu, Kun Lv, Qi-Long Wan, Zu-Bing Li, Zhi Li PurposeThe purpose of this study was to describe the application of computer-assisted navigation for the retrieval of accidentally displaced mandibular third molars.Patients and MethodsAll patients identified as having an accidentally displaced mandibular third molar or root fragment presented to the authors' department from April 2013 through June 2015 were included in this prospective study. The retrieval of th... περισσότερα »
Static and Dynamic Navigation for Dental Implant Placement
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Michael S. Block from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1MWW1sB via IFTTT
Sialendoscopy of salivary glands affected by Sjögren’s syndrome. A randomized controlled pilot study
Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Derk Jan Jager, K. Hakki Karagozoglu, Floor Maarse, Henk S. Brand, Tim Forouzanfar PurposeSialendoscopy of the major salivary glands could possibly alleviate the oral symptoms of Sjogren's syndrome and restore salivary function. The aim of this pilot study was therefore to evaluate the effect of sialendoscopy of the major salivary glands on salivary flow, saliva composition and mouthfeel in Sjögren's syndrome patients and to collect data for sample-size analysis for a larg... περισσότερα »
A marker placement laser device for improving repeatability in 3D-foot motion analysis
Publication date: February 2016 *Source:*Gait & Posture, Volume 44 Author(s): Eva Kalkum, Stefan van Drongelen, Johannes Mussler, Sebastian I. Wolf, Benita Kuni BackgroundIn 3D gait analysis, the repeated positioning of markers is associated with a high error rate, particularly when using a complex foot model with many markers. Therefore, a marker placement laser device was developed that ensures a reliable repositioning of markers. We report the development and reliability of this device for the foot at different tape conditions.MethodsIn 38 subjects, markers were placed at the foo...περισσότερα »
POGZ truncating alleles cause syndromic intellectual disability.
*POGZ truncating alleles cause syndromic intellectual disability.* Genome Med. 2016;8(1):3 Authors: White J, Beck CR, Harel T, Posey JE, Jhangiani SN, Tang S, Farwell KD, Powis Z, Mendelsohn NJ, Baker JA, Pollack L, Mason KJ, Wierenga KJ, Arrington DK, Hall M, Psychogios A, Fairbrother L, Walkiewicz M, Person RE, Niu Z, Zhang J, Rosenfeld JA, Muzny DM, Eng C, Beaudet AL, Lupski JR, Boerwinkle E, Gibbs RA, Yang Y, Xia F, Sutton VR Abstract BACKGROUND: Large-scale cohort-based whole exome sequencing of individuals with neurodevelopmental disorders (NDDs) has identified numerous nov... περισσότερα »
Reduced evoked motor and sensory potential amplitudes in obstructive sleep apnoea patients
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Summary It is unknown to what extent chronic intermittent hypoxaemia in obstructive sleep apnoea causes damage to the motor and sensory peripheral nerves. It was hypothesized that patients with obstructive sleep apnoea would have bilaterally significantly impaired amplitudes of both motor and sensory peripheral nerve-evoked potentials of both lower and upper limbs. An observational study […]
Muscle Weakness Thresholds for Prediction of Diabetes in Adults
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Background Despite the known links between weakness and early mortality, what remains to be fully understood is the extent to which strength preservation is associated with protection from cardiometabolic diseases, such as diabetes. Purpose The purposes of this study were to determine the association between muscle strength and diabetes among adults, and to identify […]
Is endoscopic ear surgery an alternative to the modified Bondy technique for limited epitympanic cholesteatoma?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract The objective of this study is to evaluate the outcomes of the modified Bondy’s technique performed at our center and for limited epitympanic cholesteatomas and to debate the purported benefits of endoscopic surgery for the same indication. This is a retrospective study. 269 ears of 258 patients with a minimum of 5-year follow-up that […]
Resource allocation in an annual herb: Effects of light, mycorrhizal fungi, and defoliation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: February 2016 Source:Acta Oecologica, Volume 71 Author(s): Ana Aguilar-Chama, Roger Guevara Concurrent interactions and the availability of resources (e.g., light) affect the cost/benefit balance during mutualistic and antagonistic interactions, as well as plant resource allocation patterns. Mycorrhizal interactions and herbivory concur in most plants, where mycorrhizae can enhance the uptake of soil nutrients […]
The effective stimulating pulse for restoration of blink function in unilateral facial nerve paralysis rabbits, verified by a simple FES system
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract The trains of 200 ms biphasic square pulses with the width of 9 ms delivered at 50 Hz were found to be the most suitable and effective mean as stimulation in FES system of restoring the blink function in unilateral facial nerve paralysis rabbit model. FES system is a reliable tool for these patients. […]
Ecological Innovation: Biomimicry as a New Way of Thinking and Acting Ecologically
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract In this article, we critically reflect on the concept of biomimicry. On the basis of an analysis of the concept of biomimicry in the literature and its philosophical origin, we distinguish between a strong and a weaker concept of biomimicry. The strength of the strong concept of biomimicry is that nature is seen as […]
Photocoagulation therapy for laryngeal dysplasia using angiolytic lasers
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract In the management of laryngeal pre-cancerous lesions such as dysplasia or carcinoma in situ (CIS), it is important that lesion regression occur without any complications. As a minimally invasive treatment option, photocoagulation therapy using angiolytic lasers has been attracting attention. Therapeutic effects have been reported for this type of treatment, however, vocal function after […]
Inhibition of miR-15b decreases cell migration and metastasis in colorectal cancer
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Colorectal cancer (CRC) has a high prevalence and mortality rate. Biomarkers for predicting the recurrence of CRC are not clinically available. This study investigated the role of circulating miR-15b in the prediction of CRC recurrence and the associated mechanism. miR-15b levels in plasma and tissues were measured by real-time PCR. Metastasis suppressor-1 (MTSS1) and […]
Short-term effect of caffeine on olfactory function in hyposmic patients
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract The purpose of this study was to investigate the potential effects of caffeine in patients with olfactory loss. The suggested mechanisms of action consist in the non-selective blocking of adenosine receptors as well as inhibition of the phospodiesterase. Olfactory function was tested twice in 76 hyposmic patients either because of URTI or because of […]
Correlations of fascin-1 and cadherin-17 protein expression with clinicopathologic features and prognosis of patients with gastric cancer
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract We aim to explore the associations of fascin-1 and cadherin-17 in gastric cancer (GC) to the clinicopathologic features and prognosis of GC. Case group included 204 GC tissues while control group comprised 204 paired adjacent cancer tissues. Expressions of fascin-1 and cadherin-17 were measured with immunohistochemistry and western blot and then analyzed statistically in […]
Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.
*Human Head and Neck Squamous Cell Carcinoma-Associated Semaphorin 4D Induces Expansion of Myeloid-Derived Suppressor Cells.* J Immunol. 2016 Jan 6; Authors: Younis RH, Han KL, Webb TJ Abstract One of the mechanisms by which malignancies can induce immune suppression is through the production of cytokines that affect the maturation and differentiation of inflammatory cells in the tumor microenvironment. Semaphorin 4D (Sema4D) is a proangiogenic cytokine produced by several malignancies, which has been described in the regulation of the immune system. In the present study, we exa... περισσότερα »
A family with pheochromocytoma-paraganglioma inherited tumour syndrome. Serial 18F-DOPA PET/CT investigations.
*A family with pheochromocytoma-paraganglioma inherited tumour syndrome. Serial 18F-DOPA PET/CT investigations.* Nuklearmedizin. 2016 Jan 7;55(1) Authors: Knie B, Plotkin M, Zschieschang P, Prasad V, Moskopp D Abstract AIM: Hereditary pheochromocytoma-paraganglioma syndromes are characterized by multiple pheochromocytomas (PCC) and paragangliomas (PGLs), inherited in an autosomal dominant manner. Early detection and removal of tumours may prevent or minimize complications related to mass effects and malignant transformation. Having confirmed the diagnosis, it is important to loca... περισσότερα »
A unilateral septal flap based on the anterior ethmoidal artery (Castelnuovo's flap): CT cadaver study.
*A unilateral septal flap based on the anterior ethmoidal artery (Castelnuovo's flap): CT cadaver study.* Surg Radiol Anat. 2016 Jan 6; Authors: Gras-Cabrerizo JR, García-Garrigós E, Ademá-Alcover JM, Sarandeses-Garcia A, Martel-Martin M, Montserrat-Gili JR, Gras-Albert JR, Massegur-Solench H Abstract OBJECTIVE: We describe our experience for repair septal perforation with a septal flap and we analyse the route of the septal branch of the anterior ethmoidal artery (AEA) in the septum area with a radiological anatomy study in order to perform this flap. STUDY DESIGN: We carry out...περισσότερα »
Cardiac lymphangioma presenting as intrapericardial cystic mass.
*Cardiac lymphangioma presenting as intrapericardial cystic mass.* Saudi Med J. 2016 Jan;37(1):90-2 Authors: Lone NA, Naikoo BA, Khan NA Abstract Cystic lymphangioma usually confined to head and neck is a well-recognized tumor that occurs during childhood. However, a cardiac lymphangioma is exceptionally uncommon and a particularly rare form of disease. We report a case of cystic lymphangioma arising from the right ventricular wall, and presenting as pericardial mass in a young female, who presented with a history of exercise intolerance in the form of breathlessness on exertion ...περισσότερα »
Prognostic impact of salvage treatment on hearing recovery in patients with sudden sensorineural hearing loss refractory to systemic corticosteroids: A retrospective observational study.
*Prognostic impact of salvage treatment on hearing recovery in patients with sudden sensorineural hearing loss refractory to systemic corticosteroids: A retrospective observational study.* Auris Nasus Larynx. 2015 Dec 28; Authors: Nakagawa T, Yamamoto M, Kumakawa K, Usami SI, Hato N, Tabuchi K, Takahashi M, Fujiwara K, Sasaki A, Komune S, Yamamoto N, Hiraumi H, Sakamoto T, Shimizu A, Ito J Abstract OBJECTIVE: To determine the prognostic factors for hearing recovery in patients with sudden sensorineural hearing loss (SSHL) refractory to systemic corticosteroids following salvage ...περισσότερα »
Topical application of timolol decreases the severity and frequency of epistaxis in patients who have previously undergone nasal dermoplasty for hereditary hemorrhagic telangiectasia.
*Topical application of timolol decreases the severity and frequency of epistaxis in patients who have previously undergone nasal dermoplasty for hereditary hemorrhagic telangiectasia.* Auris Nasus Larynx. 2015 Dec 28; Authors: Ichimura K, Kikuchi H, Imayoshi S, Dias MS Abstract OBJECTIVE: Hereditary hemorrhagic telangiectasia (HHT) is widely known to cause bleeding that is difficult to control because of the associated vascular wall fragility. Although nasal dermoplasty results in decreased severity and frequency of nasal bleeding in patients with HHT, it does not eradicate epi... περισσότερα »
Oral and Maxillofacial Surgery Foundation Research and Fellowship Awards: A 26-Year Review at Massachusetts General Hospital and Harvard School of Dental Medicine
Publication date: February 2016 *Source:*Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Gino Inverso, Sung-Kiang Chuang, Leonard B. Kaban PurposeThe purpose of this study was to review outcomes of the Oral and Maxillofacial Surgery (OMS) Foundation's funding awards to members of the OMS department at Massachusetts General Hospital (MGH) in terms of projects completed, abstracts presented, peer-reviewed publications, and career trajectories of recipients.Materials and MethodsData were collected from MGH and OMS Foundation records and interviews with award rec... περισσότερα »
POGZ truncating alleles cause syndromic intellectual disability.
*POGZ truncating alleles cause syndromic intellectual disability.* Genome Med. 2016;8(1):3 Authors: White J, Beck CR, Harel T, Posey JE, Jhangiani SN, Tang S, Farwell KD, Powis Z, Mendelsohn NJ, Baker JA, Pollack L, Mason KJ, Wierenga KJ, Arrington DK, Hall M, Psychogios A, Fairbrother L, Walkiewicz M, Person RE, Niu Z, Zhang J, Rosenfeld JA, Muzny DM, Eng C, Beaudet AL, Lupski JR, Boerwinkle E, Gibbs RA, Yang Y, Xia F, Sutton VR Abstract BACKGROUND: Large-scale cohort-based whole exome sequencing of individuals with neurodevelopmental disorders (NDDs) has identified numerous nove... περισσότερα »
Masthead
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: February 2016 Source:Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1n7vbJv via IFTTT
Effects of Le Fort I Osteotomy on the Nasopharyngeal Airway—6-Month Follow-Up
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: February 2016 Source:Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Mohammed Almuzian, Anas Almukhtar, Xiangyang Ju, Ali Al-Hiyali, Philip Benington, Ashraf Ayoub PurposeThe literature discussing the impact of a single Le Fort I osteotomy on nasopharyngeal airways is limited. This study assessed the volumetric changes in the nasopharyngeal airway after […]
Role of Negative-Pressure Wound Therapy in the Management of Submandibular Fistula After Reconstruction for Osteoradionecrosis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: February 2016 Source:Journal of Oral and Maxillofacial Surgery, Volume 74, Issue 2 Author(s): Da-ming Zhang, Zhao-hui Yang, Pei-lin Zhuang, You-yuan Wang, Wei-liang Chen, Bin Zhang PurposeAlthough negative-pressure wound therapy (NPWT) for complicated wounds has been extensively studied, it is rarely used in cases involving a submandibular fistula due to radiation-induced osteoradionecrosis of the […]
Selective versus comprehensive neck dissection in T1/2 oral squamous cell carcinoma patients with cN0pN+ neck
Publication date: Available online 7 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Li-zhong Liang, Xiang-qi Liu, Qian-ying Kong, Gui-qing Liao PurposeThere is still no consensus on the oncologic safety of selective neck dissection (SND) in the management of pathologically positive neck in oral cavity squamous cell carcinoma patients. This study aimed to compare the clinical outcome between the selective and comprehensive neck dissection (CND) for T1 and T2 oral cancer patients with clinically negative but pathologically positive neck.Materials and Method... περισσότερα »
The role of diet in the overlap between gastroesophageal reflux disease and functional dyspepsia
The Turkish Journal of Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1OfbshP Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Comparison of percutaneous radiofrequency ablation and CyberKnife for initial solitary hepatocellular carcinoma: A pilot study
World Journal of Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1PStP0y Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Diversity in endocrinology practice: the case of Ramadan.
Related Articles *Diversity in endocrinology practice: the case of Ramadan.* Hormones (Athens). 2016 Jan 6; Authors: Ilias I, Tayeh LS, Pachoundakis I PMID: 26732169 [PubMed - as supplied by publisher] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1UAFzEc via IFTTT
Βones, stones and androgen deprivation therapy.
Related Articles *Βones, stones and androgen deprivation therapy.* Hormones (Athens). 2016 Jan 6; Authors: Arrabal-Polo MÁ, Cano-García MD, Arrabal-Martín M PMID: 26732168 [PubMed - as supplied by publisher] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/22Oc8Vl via IFTTT
Does ambient light at night reduce total melatonin production?
Related Articles *Does ambient light at night reduce total melatonin production?* Hormones (Athens). 2016 Jan 6; Authors: Kyba CC, Kantermann T PMID: 26732167 [PubMed - as supplied by publisher] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1UAFznz via IFTTT
Landmarks in the history of adrenal surgery.
Related Articles *Landmarks in the history of adrenal surgery.* Hormones (Athens). 2016 Jan 6; Authors: Papadakis M, Manios A, Schoretsanitis G, Trompoukis C PMID: 26732166 [PubMed - as supplied by publisher] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1UAFAbi via IFTTT
TSH-secreting pituitary adenomas treated by gamma knife radiosurgery: our case experience and a review of the literature.
Related Articles *TSH-secreting pituitary adenomas treated by gamma knife radiosurgery: our case experience and a review of the literature.* Hormones (Athens). 2016 Jan 6; Authors: Mouslech Z, Somali M, Sakali AK, Savopoulos C, Mastorakos G, Hatzitolios AI Abstract A 43-year-old woman, previously misdiagnosed as having primary hyperthyroidism and treated with antithyroid drugs, presented to us with overt hyperthyroidism, high levels of thyroid hormones and elevated thyroid-stimulating hormone (TSH). Μagnetic resonance imaging (MRI) revealed a pituitary microadenoma extending sup...περισσότερα »
Pasireotide for malignant insulinoma.
Related Articles *Pasireotide for malignant insulinoma.* Hormones (Athens). 2016 Jan 6; Authors: Tirosh A, Stemmer SM, Solomonov E, Elnekave E, Saeger W, Ravkin Y, Nir K, Talmor Y, Shimon I Abstract Malignant insulinoma usually has a poor prognosis, as no efficient medical treatment is available. The somatostatin analogs octreotide and lanreotide have limited ability to control the hypoglycemic events. Pasireotide is a multi-receptor targeted somatostatin-analog with improved affinity for SSTR5. There is to date no reported treatment experience with this drug in such tumors. CAS... περισσότερα »
Multiple endocrine neoplasia type 1 associated with a new germline Men1 mutation in a family with atypical tumor phenotype.
Related Articles *Multiple endocrine neoplasia type 1 associated with a new germline Men1 mutation in a family with atypical tumor phenotype.* Hormones (Athens). 2016 Jan 6; Authors: Perakakis N, Flohr F, Kayser G, Thomusch O, Parsons L, Billmann F, von Dobschuetz E, Rondot S, Seufert J, Laubner K Abstract BACKGROUND: Multiple endocrine neoplasia type 1 (MEN1) is an autosomal-dominant hereditary disorder associated with the development of endocrine tumors due to reduced expression of the tumor suppressor protein menin. Recent studies indicate a general role of menin in carcinogen... περισσότερα »
The growth endocrine axis and inflammatory responses after laparoscopic cholecystectomy.
Related Articles *The growth endocrine axis and inflammatory responses after laparoscopic cholecystectomy.* Hormones (Athens). 2016 Jan 6; Authors: Floros T, Philippou A, Bardakostas D, Mantas D, Koutsilieris M Abstract OBJECTIVE: It is well known that conventional surgery leads to detrimental immune and catabolic responses, thus there is growing interest in the effect of minimally invasive techniques on postoperative endocrine and immune function. The aim of this prospective study was to evaluate the growth hormone (GH)/insulin-like growth factor-1 (IGF-1)/IGF binding protein-3... περισσότερα »
Long-term follow-up results of growth hormone therapy for patients with adult growth hormone deficiency.
Related Articles *Long-term follow-up results of growth hormone therapy for patients with adult growth hormone deficiency.* Hormones (Athens). 2016 Jan 6; Authors: Ikeda H, Kudo M Abstract OBJECTIVE: We evaluated the long-term effects of growth hormone (GH) on markers of quality of life, glucose metabolism, and lipid metabolism to validate the adequacy of long-term GH replacement therapy for adult GH deficiency (AGHD). DESIGN: Eighty-three of 100 sequentially followed patients who received GH therapy were selected for this study. Forty-nine were men aged 26 to 78 years (mean, 52...περισσότερα »
PProgesterone pretreatment increases the stress response to social isolation in ewes.
Related Articles *PProgesterone pretreatment increases the stress response to social isolation in ewes.* Hormones (Athens). 2016 Jan 6; Authors: Freitas-de-Melo A, Damián JP, Hötzel MJ, Banchero G, Ungerfeld R Abstract OBJECTIVE: In rodents, progesterone (P4) pretreatment increases anxiety and response to stressors. Social isolation is a stressor that generates physiological and behavioural stress responses in sheep. The aim of the study was to compare the stress response of anoestrous ewes previously treated or not with P4 to the social isolation test. DESIGN: Ten ewes received ...περισσότερα »
Sheehan's syndrome in Xinjiang: Clinical characteristics and laboratory evaluation of 97 patients.
Related Articles *Sheehan's syndrome in Xinjiang: Clinical characteristics and laboratory evaluation of 97 patients.* Hormones (Athens). 2016 Jan 6; Authors: Du GL, Liu ZH, Chen M, Ma R, Jiang S, Shayiti M, Zhu J, Yusufu A Abstract OBJECTIVE: To evaluate the clinical and hormonal characteristics of patients with Sheehan's syndrome in Xinjiang, China. METHODS: 97 cases diagnosed as Sheehan's syndrome in our hospital from 1999 to 2013 were retrospectively reviewed. The medical history, physical examination findings and hormonal profiles were documented and analyzed. RESULTS: The mea... περισσότερα »
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