Prone positioning and positive end-expiratory pressure can improve pulmonary gas exchange and respiratory mechanics
Effects of Prone Position and Positive End-Expiratory Pressure on Noninvasive Estimators of ICP: A Pilot Study.: Background: Prone positioning and positive end-expiratory pressure can improve pulmonary gas exchange and respiratory mechanics. However, they may be associated with the development of intracranial hypertension. Intracranial pressure (ICP) can be noninvasively estimated from the sonographic measurement of the optic nerve sheath diameter (ONSD) and from the transcranial Doppler analysis of the pulsatility (ICPPI) and the diastolic component (ICPFVd) of the velocity wavefor...περισσότερα »
Erythromycin in Trauma Patients with a Full Stomach
Ultrasound Assessment of the Prokinetic Effect of Erythromycin in Trauma Patients with a Full Stomach: A Case Series: In this preliminary prospective noninterventional study, we assessed the prokinetic effect of 3 mg•kg−1 erythromycin in nonfasted emergency trauma patients. Ultrasonographic measurements of the antral area were performed 30 minutes and immediately before the erythromycin infusion and serially at 30, 60, and 90 minutes after the start of the infusion. Gastric emptying rates before and after erythromycin infusion, and at each 30-minute period after erythromycin infusio...περισσότερα »
Head-Elevated Patient Positioning Decreases Complications of Emergent Tracheal Intubation in the Ward and Intensive Care Unit
Head-Elevated Patient Positioning Decreases Complications of Emergent Tracheal Intubation in the Ward and Intensive Care Unit: [image: image] BACKGROUND: Based on the data from elective surgical patients, positioning patients in a back-up head-elevated position for preoxygenation and tracheal intubation can improve patient safety. However, data specific to the emergent setting are lacking. We hypothesized that back-up head-elevated positioning would be associated with a decrease in complications related to tracheal intubation in the emergency room environment. METHODS: This retros... περισσότερα »
The Belmont® Rapid Infuser
An Evaluation of Induced Failure Modes in the Belmont® Rapid Infuser: [image: image] BACKGROUND: Rapid infusers are vital tools during massive hemorrhage and resuscitation. Sporadic reports of overheating and shutdown of the Belmont® Rapid Infuser, a commonly used system, have been attributed to 1-sided clot blockage of the fluid path. We investigated multiple causes of failure of this device. METHODS: Packed red blood cells and thawed fresh frozen plasma with normal saline solution were used as base fluids for serial 10-minute trials using standard disposable sets in 2 Belmont dev...περισσότερα »
The Effect of Intravenous Dexamethasone on Sugammadex Reversal Time in Children Undergoing Adenotonsillectomy
The Effect of Intravenous Dexamethasone on Sugammadex Reversal Time in Children Undergoing Adenotonsillectomy: BACKGROUND: Dexamethasone has been shown to cause inhibition of sugammadex reversal in functionally innervated human muscle cells. In this prospective, double-blind, randomized, controlled study, we evaluated the effect of dexamethasone on the reversal time of sugammadex in children undergoing tonsillectomy and/or adenoidectomy. METHODS: We recruited 60 patients with ASA physical status I to II, between the ages of 3 and 8 years, scheduled for elective tonsillectomy and/or ... περισσότερα »
The Use of Respiratory Acoustic Monitoring in Children Receiving Postoperative Opioid Infusions
An Ethnographic Observational Study to Evaluate and Optimize the Use of Respiratory Acoustic Monitoring in Children Receiving Postoperative Opioid Infusions: [image: image]BACKGROUND: Respiratory depression in children receiving postoperative opioid infusions is a significant risk because of the interindividual variability in analgesic requirement. Detection of respiratory depression (or apnea) in these children may be improved with the introduction of automated acoustic respiratory rate (RR) monitoring. However, early detection of adverse events must be balanced with the risk of...περισσότερα »
Airway obstruction by an unexpected equipment damage
Airway obstruction by an unexpected equipment damage: Intubating introducers are often used to facilitate difficult endotracheal intubation. We report a case in which a Frova catheter was used for insertion of a laser-resistant endotracheal tube and in which a strip of plastic was shaved off from the catheter. The plastic strip formed a convolute mass, causing relevant airway obstruction. Clinicians should be aware of this potentially dangerous complication and should be cautious in using Frova intubating introducers in combination with laser-resistant tubes.
A case of anaphylaxis apparently induced by sugammadex and rocuronium in successive surgeries
A case of anaphylaxis apparently induced by sugammadex and rocuronium in successive surgeries: Rocuronium is the agent most frequently involved in perioperative anaphylaxis, and sugammadex has also been known to induce anaphylactic reactions. We describe a case of successive anaphylactic episodes that seemed to be induced by clinical doses of rocuronium and sugammadex. The patient was a 19-year-old woman who had a medical history of asthma, but no history of surgery. She had been injured in a fall, and several surgeries were scheduled for multiple bone fractures. At the first surger...περισσότερα »
Awake intubating laryngeal mask airway placement in a morbidly obese patient with ankylosing spondylitis and unstable thoracic spine
Awake intubating laryngeal mask airway placement in a morbidly obese patient with ankylosing spondylitis and unstable thoracic spine: Intubating laryngeal mask airways can be used to provide continuous ventilation throughout intubation. This is a case of a morbidly obese (body mass index = 58) 65-year-old woman with T10 and T11 compression fractures. Optimal positioning for airway management was hindered by her unstable spine, minimal neck range of motion, and extreme pain with any movement. An intubating laryngeal mask airway was placed in the awake, topically anesthetized patient,...περισσότερα »
Prediction of obstructive sleep apnea using visual photographic analysis
Prediction of obstructive sleep apnea using visual photographic analysis: [image: gr1.sml] Obstructive sleep apnea (OSA) has been historically underdiagnosed and may be associated with grave perioperative complications. The ASA and American Academy of Sleep Medicine recommend OSA screening prior to surgery; however, only a minority of patients are screened. The objective of this study was to determine the proficiency of anesthesiologists, otolaryngologists, and internists at predicting the presence of OSA by visual photographic analysis without the use of a computer program to ... περισσότερα »
Endotracheal tube displacement during head and neck movements. Observational clinical trial
Endotracheal tube displacement during head and neck movements. Observational clinical trial: [image: gr1.sml] Measure the displacements of endotracheal tube (ETT) tip displacement during head and neck movements. Highlights - •Endotracheal tube displacement was measured during maximal head and neck movements. - •In most cases, tip of the endotracheal tube was withdrawn during neck extension. - •With regard to the carina, a wide disparity of tube positioning was noted. AbstractStudy Objective Measure the displacements of endotracheal tube (ETT) tip displacem... περισσότερα »
Changes in macrophage function modulated by the lipid environment
Changes in macrophage function modulated by the lipid environment: Macrophages (Ms) play a critical role in the defense against pathogens, orchestrating the inflammatory response during injury and maintaining tissue homeostasis. During these processes, macrophages encounter a variety of environmental conditions that are likely to change their gene expression pattern, which modulates their function. In this study, we found that murine Ms displayed two different subpopulations characterized by differences in morphologies, expression of surface markers and phagocytic capacity under no...περισσότερα »
Heat shock proteins and chronic fatigue in primary Sjögrens syndrome
Heat shock proteins and chronic fatigue in primary Sjögrens syndrome: Fatigue occurs frequently in patients with cancer, neurological diseases and chronic inflammatory diseases, but the biological mechanisms that lead to and regulate fatigue are largely unknown. When the innate immune system is activated, heat shock proteins (HSPs) are produced to protect cells. Some extracellular HSPs appear to recognize cellular targets in the brain, and we hypothesize that fatigue may be generated by specific HSPs signalling through neuronal or glial cells in the central nervous system. From a ... περισσότερα »
Pollen Allergens for Molecular Diagnosis
Pollen Allergens for Molecular Diagnosis: AbstractPollen allergens are one of the main causes of type I allergies affecting up to 30 % of the population in industrialized countries. Climatic changes affect the duration and intensity of pollen seasons and may together with pollution contribute to increased incidences of respiratory allergy and asthma. Allergenic grasses, trees, and weeds often present similar habitats and flowering periods compromising clinical anamnesis. Molecule-based approaches enable distinction between genuine sensitization and clinically mostly irrelevant IgE ... περισσότερα »
Baked Egg and Milk Exposure as Immunotherapy in Food Allergy
Baked Egg and Milk Exposure as Immunotherapy in Food Allergy: AbstractBaked milk and egg have the potential to act as a form of oral immunotherapy (OIT). Clinical studies have shown that a majority of milk- and egg-allergic children can tolerate these allergens modified in baked form, and immunologic changes reported in subjects ingesting baked milk and egg mirror those seen in food allergy OIT trials. In addition, several studies have indicated that resolution of milk and egg allergies occur sooner in populations regularly ingesting baked milk and egg. Oral food challenges remain ... περισσότερα »
Eccrine spiradenomas : Multiple swellings on the chest and the nape of the neck
A rare case of eccrine spiradenoma—treatment and management: AbstractA young male patient presented with multiple swellings on his chest and the nape of his neck. Physical examination revealed multiple small papulonodular swellings measuring 0.5 × 0.5 cm to 2 × 2 cm, that were soft without discharge with no surrounding skin changes or induration. Skin biopsy samples were diagnosed as benign adnexal neoplasm consistent with eccrine spiradenoma, trichoepithelioma, and cylindroma, i.e., Brooke–Spiegler syndrome. Having confirmed this to be a case of eccrine spiradenoma, surgical excis...περισσότερα »
Vancomycin-related partial necrosis of congenital hemangioma
Vancomycin-related partial necrosis of congenital hemangioma: AbstractThe term hemangioma refers to the common tumor of infancy that exhibits rapid postnatal growth and slow regression during childhood. Infantile hemangiomas are benign vascular neoplasms that develop from the dermal capillary network. Vancomycin is a bactericidal antibiotic agent commonly used in the treatment of infections caused by Gram-positive organisms. The most common adverse effect of intravenously administered vancomycin is “red man syndrome” (RMS), which is associated with the rapid infusion of large doses...περισσότερα »
Modification of the anterolateral thigh free flap design for reconstruction after laryngo-pharyngoesophagectomy
Modification of the anterolateral thigh free flap design for reconstruction after laryngo-pharyngoesophagectomy: AbstractThe anterolateral thigh free flap (ALTFF) has become the favourable fasciocutaneous flap for reconstruction of laryngo-pharyngoesophagectomy (LPO) defects. Reconstruction of these defects can be challenging. We report our experience with a new flap design based on the traditional ALTFF template for single-stage reconstruction of circumferential LPO defects with anterior neck skin deficits in previously irradiated patients. The design uses the traditional tubed sk... περισσότερα »
A next-generation antimicrobial wound dressing (NGAD; AQUACEL® Ag+ Extra™ dressing)
Clinical safety and effectiveness evaluation of a new antimicrobial wound dressing designed to manage exudate, infection and biofilm: Abstract The objective of this work was to evaluate the safety and effectiveness of a next-generation antimicrobial wound dressing (NGAD; AQUACEL® Ag+ Extra™ dressing) designed to manage exudate, infection and biofilm. Clinicians were requested to evaluate the NGAD within their standard protocol of care for up to 4 weeks, or as long as deemed clinically appropriate, in challenging wounds that were considered to be impeded by suspected biofilm or infe...περισσότερα »
A new antimicrobial wound dressing designed to manage exudate, infection and biofilm
Clinical safety and effectiveness evaluation of a new antimicrobial wound dressing designed to manage exudate, infection and biofilm: Abstract The objective of this work was to evaluate the safety and effectiveness of a next-generation antimicrobial wound dressing (NGAD; AQUACEL® Ag+ Extra™ dressing) designed to manage exudate, infection and biofilm. Clinicians were requested to evaluate the NGAD within their standard protocol of care for up to 4 weeks, or as long as deemed clinically appropriate, in challenging wounds that were considered to be impeded by suspected biofilm or infe...περισσότερα »
Melanoma Extirpation with Immediate Reconstruction
Melanoma Extirpation with Immediate Reconstruction: The Oncologic Safety and Cost Savings of Single Stage Treatment.: Introduction: The timing of reconstruction following melanoma extirpation remains controversial, with some advocating definitive reconstruction only when the results of permanent pathology are available. The authors aim to evaluate oncologic safety and cost benefit of single stage neoplasm extirpation with immediate reconstruction. Methods: The authors reviewed all patients treated with biopsy-proven melanoma followed by immediate reconstruction during a three-year p... περισσότερα »
The Pediatric Temporomandibular Joint Synovitis
Quantifying Synovial Enhancement of the Pediatric Temporomandibular Joint via Oral and Maxillofacial Surgery Publication date: Available online 21 March 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Zachary S. Peacock, Pouya Vakilian, Paul Caruso, Cory M. Resnick, Mark Vangel, Leonard B. Kaban PurposeThe purpose of this study was to assess a novel method for quantifying TMJ synovial enhancement on gadolinium-enhanced MRI and to establish normative values to allow early detection of synovitis.MethodsThis is a retrospective cohort study of pediatric patients (ages 0-...περισσότερα »
The radial forearm free flap versus the ulnar forearm free flap
Perforator anatomy of the radial forearm free flap versus the ulnar forearm free flap for head and neck reconstruction via Oral and Maxillofacial Surgery Publication date: Available online 21 March 2016 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): D.D. Hekner, T.A.P. Roeling, E.M. Van Cann The aim of this study was to investigate the vascular anatomy of the distal forearm in order to optimize the choice between the radial forearm free flap and the ulnar forearm free flap and to select the best site to harvest the flap. The radial and ulnar arteries of seve... περισσότερα »
Cleansing effect of acidic L-arginine on human oral biofilm
Cleansing effect of acidic L-arginine on human oral biofilm: Abstract BackgroundDental plaque formed on tooth surfaces is a complex ecosystem composed of diverse oral bacteria and salivary components. Accumulation of dental plaque is a risk factor for dental caries and periodontal diseases. L-arginine has been reported to decrease the risk for dental caries by elevating plaque pH through the activity of arginine deiminase in oral bacteria. Here we evaluated the potential of L-arginine to remove established oral biofilms. MethodsBiofilms were formed using human saliva mixed with... περισσότερα »
Volatile sulfur compounds (VSCs) including hydrogen sulfide (H2S) and methyl mercaptan (CH3SH)
A randomized, double-blind, crossover, placebo-controlled clinical trial to assess effects of the single ingestion of a tablet containing lactoferrin, lactoperoxidase, and glucose oxidase on oral malodor: Abstract BackgroundThe main components of oral malodor have been identified as volatile sulfur compounds (VSCs) including hydrogen sulfide (H2S) and methyl mercaptan (CH3SH). VSCs also play an important role in the progression of periodontal disease. The aim of the present study was to assess the effects of the single ingestion of a tablet containing 20 mg of lactoferrin, 2.6 mg ... περισσότερα »
The ingestion of a tablet containing lactoferrin, lactoperoxidase, and glucose oxidase has suppressive effects on oral malodor
A randomized, double-blind, crossover, placebo-controlled clinical trial to assess effects of the single ingestion of a tablet containing lactoferrin, lactoperoxidase, and glucose oxidase on oral malodor: Abstract BackgroundThe main components of oral malodor have been identified as volatile sulfur compounds (VSCs) including hydrogen sulfide (H2S) and methyl mercaptan (CH3SH). VSCs also play an important role in the progression of periodontal disease. The aim of the present study was to assess the effects of the single ingestion of a tablet containing 20 mg of lactoferrin, 2.6 mg ... περισσότερα »
Columellar Lengthening
Modified Activation Technique for Nasal Stent of Nasoalveolar Molding Appliance for Columellar Lengthening in Bilateral Cleft Lip/Palate: Abstract Bilateral cleft lip/cleft palate is associated with nasal deformities typified by a short columella. The presurgical nasoalveolar molding (NAM) therapy approach includes reduction of the size of the intraoral alveolar cleft as well as positioning of the surrounding deformed soft tissues and cartilages. In a bilateral cleft patient, NAM, along with columellar elongation, eliminates the need for columellar lengthening surgery. Thus the fre... περισσότερα »
Modified Activation Technique for Nasal Stent of Nasoalveolar Molding Appliance for Columellar Lengthening in Bilateral Cleft Lip/Palate
Modified Activation Technique for Nasal Stent of Nasoalveolar Molding Appliance for Columellar Lengthening in Bilateral Cleft Lip/Palate: Abstract Bilateral cleft lip/cleft palate is associated with nasal deformities typified by a short columella. The presurgical nasoalveolar molding (NAM) therapy approach includes reduction of the size of the intraoral alveolar cleft as well as positioning of the surrounding deformed soft tissues and cartilages. In a bilateral cleft patient, NAM, along with columellar elongation, eliminates the need for columellar lengthening surgery. Thus the fre... περισσότερα »
Delivery of RANKL-Binding Peptide OP3-4 Promotes BMP-2-Induced Maxillary Bone Regeneration
Delivery of RANKL-Binding Peptide OP3-4 Promotes BMP-2-Induced Maxillary Bone Regeneration: Although bone morphogenetic protein 2 (BMP-2) is known to stimulate osteogenesis, there is evidence that high doses of BMP-2 can lead to side effects, including inflammation and carcinogenesis. The supplementation of other bone-augmenting agents is considered helpful in preventing such side effects by reducing the amount of BMP-2 required to obtain a sufficient amount of bone. We recently showed that a receptor activator of nuclear factor B ligand (RANKL)–binding peptide promotes osteoblast ... περισσότερα »
The Dynamic Visual Acuity Test for Vestibular Screening.
Reliability and Normative Data for the Dynamic Visual Acuity Test for Vestibular Screening.: Hypothesis: The purpose of this study was to determine reliability of computerized dynamic visual acuity (DVA) testing and to determine reference values for younger and older adults. Background: A primary function of the vestibular system is to maintain gaze stability during head motion. The DVA test quantifies gaze stabilization with the head moving versus stationary. Commercially available computerized systems allow clinicians to incorporate DVA into their assessment; however, information ... περισσότερα »
Reliability and Normative Data for the Dynamic Visual Acuity Test for Vestibular Screening.
Reliability and Normative Data for the Dynamic Visual Acuity Test for Vestibular Screening.: Hypothesis: The purpose of this study was to determine reliability of computerized dynamic visual acuity (DVA) testing and to determine reference values for younger and older adults. Background: A primary function of the vestibular system is to maintain gaze stability during head motion. The DVA test quantifies gaze stabilization with the head moving versus stationary. Commercially available computerized systems allow clinicians to incorporate DVA into their assessment; however, information ... περισσότερα »
Changes in Body Composition After EPA Supplementation in Head and Neck Patients
Changes in Body Composition After EPA Supplementation in Head and Neck Patients: *Condition*: Squamous Cell Carcinoma of Head and Neck *Interventions*: Dietary Supplement: EPA supplementation; Other: Placebo *Sponsors*: Institut Català d'Oncologia; Ferrer Internacional S.A. This study is designed to evaluate the effect of EPA supplementation on muscle mass in patients with squamous cell carcinoma of the head and neck locally advanced (stage III-IVb) to assess that supplementation with EPA can maintain muscle mass along the oncologic treatment. Other aims are to evaluate ...περισσότερα »
Icotinib With Concurrent Radiotherapy in Elderly Patients With Esophageal Cancer
Phase II Study of Icotinib With Concurrent Radiotherapy in Elderly Patients With Esophageal Cancer: *Condition*: Esophageal Cancer *Interventions*: Drug: Icotinib; Radiation: Thoracic radiotherapy *Sponsor*: First People's Hospital of Hangzhou ArmsAssigned Interventions Experimental: Icotinib & Radiotherapy Icotinib, 125mg, Po, Tid, during the course of radiotherapy; Thoracic radiotherapy, 50-60Gy, conventional fraction, 3D-CRT/IMRT. Drug: Icotinib 125mg, Po, TID during RT Other Name: Conmana Radiation: Thoracic radiotherapy involved-Field irradiaton without elective nodal ir...περισσότερα »
An Outcomes Comparison of Native Arteriovenous Fistulas, Polytetrafluorethylene Grafts, and Cryopreserved Vein Allografts
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 21 δευτερόλεπτα
Cryopreserved vein grafts can provide favorable results for dialysis access with regard to patency, access longevity, and patient survival. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1ZrfsCT via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Contrast Induced Nephropathy and Long-term Renal Decline After Percutaneous Transluminal Angioplasty for Symptomatic Peripheral Arterial Disease
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 21 δευτερόλεπτα
Administration of iodinated contrast media during endovascular procedures for peripheral arterial disease (PAD) may cause contrast induced nephropathy (CIN). The aim of the present study was to establish the incidence of CIN after these procedures and to study its association with long-term loss of kidney function, cardiovascular events, and death. from #Medicine-SfakianakisAlexandros via o.lakala70 on […]
Extracranial Systemic Embolic Events in Patients With Nonvalvular Atrial Fibrillation: Incidence, Risk Factors, and Outcomes
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 21 δευτερόλεπτα
Systemic embolic events (SEEs) in patients with atrial fibrillation (AF) remain poorly studied with the exception of ischemic stroke. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1VDb3wt via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The Effect of Dexmedetomidine on Postoperative Opioid Consumption and Pain After Major Spine Surgery.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 21 δευτερόλεπτα
BACKGROUND: Adult deformity correction spine surgery can be associated with significant perioperative pain because of inflammatory, muscular, neuropathic, and postsurgical pain. [alpha]-2 Agonists have intrinsic antinociceptive and antihyperalgesic properties that can potentially reduce both postoperative opioid consumption and pain. We hypothesized that intraoperative dexmedetomidine would reduce postoperative opioid consumption and improve pain scores in deformity […]
Sevoflurane Inhibits Glutamate-Aspartate Transporter and Glial Fibrillary Acidic Protein Expression in Hippocampal Astrocytes of Neonatal Rats Through the Janus Kinase/Signal Transducer and Activator of Transcription (JAK/STAT) Pathway.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 21 δευτερόλεπτα
BACKGROUND: The mechanisms underlying general anesthesia-induced neurotoxicity are unclear. Astrocytes have been recognized as important contributors to neuronal development. Until now, the response of the astrocytes to neonatal general anesthetic exposure has been unreported. METHODS: Postnatal day 7 rats received 2.5% sevoflurane for 6 hours. Expressions of glial fibrillary acidic protein (GFAP) and glutamate-aspartate transporter […]
A Comparative Study on the In Vitro Effects of the DNA Methyltransferase Inhibitor 5-Azacytidine (5-AzaC) in Breast/Mammary Cancer of Different Mammalian Species
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 21 δευτερόλεπτα
This study examines the effects of the DNA methyltransferase (DNMT) inhibitor 5-Azacytidine (5-AzaC) on normal and tumoral mammary cell lines derived from dogs, cats and humans, as proof of concept that small companion animals are useful models of human breast cancer. Our findings show that treatment with 5-AzaC reduces in vitro tumorigenicity in all three […]
Comments on «Is Double-Blinded Peer Review Necessary? The Effect of Blinding on Review Quality».
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 21 δευτερόλεπτα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Rfsx08 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Response to «reconstruction of large abdominal wall defects using neurotized vascular composite allografts».
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 21 δευτερόλεπτα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XLPkkq via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Implications of Rheumatic Disease and Biological Response-Modifying Agents in Plastic Surgery.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 21 δευτερόλεπτα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RfsxNr via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Response to Commentary on «Reconstruction of Large Abdominal Wall Defects Using Neurotized Vascular Composite Allografts».
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 21 δευτερόλεπτα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XLPk48 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Laser Ablation Versus Radiofrequency Ablation for Thyroid Nodules
Laser Ablation Versus Radiofrequency Ablation for Thyroid Nodules: *Condition*: Thyroid Nodule *Interventions*: Device: Percutaneous Laser Ablation; Device: Percutaneous Radiofrequency Ablation *Sponsor*: Campus Bio-Medico University ArmsAssigned Interventions Active Comparator: LA Arm Percutaneous Laser Ablation Device: Percutaneous Laser Ablation Single session with standardized approach: One or two fibers will be used for treatments including one to three illuminations with a fixed output power of 3 W, using the pullback technique. Energy for each emission will be 1200-... περισσότερα »
Haemodynamic Monitoring in Head and Neck Cancer Patients
Haemodynamic Monitoring in Head and Neck Cancer Patients: *Condition*: Postoperative Complications *Intervention*: *Sponsor*: Technische Universität München The extend of mass transfusions is known to correlate with postoperative complications. However, also crystalloid and colloidal infusions are under suspicion to cause postoperative complications. This study will capture any kind of fluid intervention perioperatively as well as intraoperatively. Intraoperative fluid management will be documented and matched with the operation steps respectively. The extend of fluid ther... περισσότερα »
Proof of Concept - Digital Electro-optical Surgical Platform as Replacement for Operational Microscopes
Proof of Concept - Digital Electro-optical Surgical Platform as Replacement for Operational Microscopes: *Condition*: Retinal Detachment *Intervention*: Device: GlasScope Surgical Microscope *Sponsor*: Elbit Systems LTD ArmsAssigned Interventions Experimental: Silicon oil removal 3D visualization Device: GlasScope Surgical Microscope 3D visualization of the poterior chamber for silicon oil removal
DNA Repair Enzyme Signature in Head and Neck Cancer (CHEMRAD)
DNA Repair Enzyme Signature in Head and Neck Cancer (CHEMRAD): *Conditions*: Head Cancer; Neck Cancer *Intervention*: Other: CHEMRAD assay *Sponsor*: Hospices Civils de Lyon Squamous cell carcinoma (HNSCC) is the most frequent form of head and neck cancer. The therapeutic choice depends on the stage of the disease and the habits of the medical teams. Surgery, radiotherapy and chemotherapy can be used, alone or combined. However, none of the existing strategies has proven its superiority. Chemotherapy and radiotherapy induce DNA damages in the tumor cells. However, cells h... περισσότερα »
Effect of polaprezinc on oral mucositis, irradiation period, and time to discharge in patients with head and neck cancer
Effect of polaprezinc on oral mucositis, irradiation period, and time to discharge in patients with head and neck cancer: [image: cover.gif?v=1&s=70581b04a54536cb9ca48b6d] Abstract Background The purpose of the present study was to determine whether polaprezinc suspension in sodium alginate (P-AG) reduces the irradiation period and time to discharge after completion of radiotherapy in patients with head and neck cancer. Methods The incidence and severity of oral mucositis, the irradiation period, and the time to discharge in patients who received radiotherapy with head and neck ... περισσότερα »
Human papillomavirus integration pattern and demographic, clinical, and survival characteristics of patients with oropharyngeal squamous cell carcinoma
Human papillomavirus integration pattern and demographic, clinical, and survival characteristics of patients with oropharyngeal squamous cell carcinoma: Abstract Background In human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (SCC), reported rates of HPV integration into the host genome vary. Among patients with oropharyngeal SCC, we determined differences in demographic, clinical, and survival characteristics between those with integrated and episomal HPV. Methods The analysis included patients with newly diagnosed oropharyngeal SCC presenting to one inst... περισσότερα »
Impact of p16 expression, nodal status, and smoking on oncologic outcomes of patients with head and neck unknown primary squamous cell carcinoma
Impact of p16 expression, nodal status, and smoking on oncologic outcomes of patients with head and neck unknown primary squamous cell carcinoma: Abstract Background The prognostic significance of human papillomavirus (HPV) in the context of head and neck squamous cell carcinoma (HNSCC) of cancer of unknown primary (CUP) origin is unclear. Methods Patients treated for CUP at the Princess Margaret Cancer Centre between 2001 and 2013 were stratified by p16 status and retrospectively reviewed. Results Of the 73 patients included, those with p16-positive tumors (63%) had less advanced no... περισσότερα »
Solitary Neurofibroma of the Soft Palate
: A Rare Entity: AbstractThe solitary neurofibroma is a benign tumor of neuronal origin uncommonly reported in the oral cavity. The possible association of this neoplasia with systemic pathologies, such as von Recklinghausen’s disease and multiple endocrine neoplasia, makes its diagnosis fundamental. Solitary isolated neurofibroma of the soft palate not associated with von Recklinghausen’s disease is an unusual tumor and probably only four cases have been reported in English literature previously. To the best of our knowledge, our case of soft palate neurofibroma in 17-year-old mal...περισσότερα »
Noninvasive Free Flap Monitoring Using Eulerian Video Magnification
Noninvasive Free Flap Monitoring Using Eulerian Video Magnification: Eulerian Video Magnification (EVM) can enhance subtle changes in videos to reveal what was once invisible to the naked eye. In this proof of concept study, we investigated using EVM as a novel form of free flap monitoring. Free flaps with skin paddles were filmed in the operating room with manipulation of their pedicles. In a representative 77-year-old female who received a latissimus dorsi-serratus-rib composite free flap, EVM was able to detect blockage of arterial or venous supply instantaneously, providing a vi... περισσότερα »
Platelet-rich-Plasma
Platelet-rich-Plasma: Zusammenfassung Hintergrund und ZielPlatelet-rich-Plasma (PRP) scheint als eine autologe und minimalinvasive Behandlungsmethode eine geeignete Alternative zu den bisherigen Behandlungsformen darzustellen, um eine Regeneration im Bereich der unteren Augenpartie erzielen zu können. Erklärt wird die Wirkung von PRP besonders in Bezug auf die Behandlung von Elastizitätsmangel und Volumendefizit im Bereich der Unterlider, für die es derzeit wenig andere Behandlungsalternativen gibt. Das körpereigene Produkt, das aus hoch konzentriertem thrombozytenreichem Plasma b... περισσότερα »
Radiofrequency ablation (RFA) and CO2 laser for early glottic cancer
Outcomes of via American Journal of Otolaryngology Publication date: Available online 22 March 2016 *Source:*American Journal of Otolaryngology Author(s): Yu Shuang, Chao Li, Xuan Zhou, Yongwang Huang, Lun Zhang ObjectiveIn the present study, the voice and functional outcomes of radiofrequency ablation (RFA) and CO2 laser for early glottic cancer were evaluated.MethodsOne hundred and sixty eight patients with early glottic cancer from October 2007 to June 2015 were included. Ninety-seven patients underwent RFA and seventy-one patients underwent CO2 laser. Recorded the operation time a... περισσότερα »
Tonsillectomy for adult obstructive sleep apnea
Tonsillectomy for adult obstructive sleep apnea: A systematic review and meta-analysis: [image: cover.gif?v=1&s=634ce17de2958347d854769c] Objectives/Hypothesis To determine if sleepiness and sleep study variables (e.g., Apnea-Hypopnea Index [AHI] and lowest oxygen saturation) improve following isolated tonsillectomy for adult obstructive sleep apnea (OSA). Study Design Systematic review and meta-analysis. Methods Nine databases (PubMed/MEDLINE included) were searched through November 24, 2015. Results Seventeen studies (n = 216 patients, 34.4 ± 10.0 years and body mass index: 29.... περισσότερα »
Scanning Electron Microscopy of the Presbylarynx
Scanning Electron Microscopy of the Presbylarynx: Objective To describe the findings on the presbylarynx under scanning electron microscopy. Study Design Cadaver study. Setting Universidade Estadual Paulista (Botucatu, São Paulo, Brazil). Subjects and Methods Sixteen vocal folds were removed during necropsies and distributed into 2 age groups: control (n = 8; aged 30-50 years) and elderly (n = 8; aged 75-92 years). The right vocal fold was dissected, fixed in glutaraldehyde 2.5%, and prepared for scanning electron microscopy. The thickness of the epithelium was measured using a ... περισσότερα »
Surgical and Audiologic Outcomes in Endoscopic Stapes Surgery
Surgical and Audiologic Outcomes in Endoscopic Stapes Surgery across 4 Institutions: Objectives To investigate intra- and postoperative outcomes of endoscopic stapes surgery. Study Design Case series with chart review. Setting Four tertiary care otologic centers. Subjects and Methods Sixty-five subjects 18 years and older who underwent endoscopic stapes surgeries were analyzed. Variables analyzed included surgical techniques and intraoperative findings. Outcomes measured included postoperative hearing and complications to date. Results Fifty-one patients met inclusion and excl... περισσότερα »
Evidenz/Transparenz: HNO – Quo vadis?
from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1o4jcwe via IFTTT
Ballondilatation der Tuba auditiva bei Mittelohroperationen
ZusammenfassungHintergrund Die Entstehung von Mittelohrerkrankungen wird u. a. auf eine unzureichende Tubenfunktion zurückgeführt. In klinischen Fallserien wurde über die Ergebnisse der Ballondilatation zur Therapie von Tubendysfunktionen berichtet. Ziel Es soll untersucht werden, ob Patienten mit geplanter Operation aufgrund einer chronischen Mittelohrerkrankung von einer zusätzlichen Ballondilatation der Tuba auditiva profitieren. Methoden In eine randomisierte, kontrollierte, für Patienten und Untersucher verblindete Studie sollen 100 erwachsene Patienten mit geplanter Operation...περισσότερα »
Maligner intraorbitaler Tumor: Primum oder Metastase?
from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1o4jcfF via IFTTT
Ist Radio(chemo)therapie wirklich der zukünftige Standard für die Behandlung von Oropharynxkarzinomen?
Zusammenfassung Die Behandlung von Patienten mit einem Plattenepithelkarzinom des Oropharynx (OPSCC) erfordert eine interdisziplinäre Zusammenarbeit. Therapieziel ist neben der Tumorkontrolle der Funktions- und Organerhalt. Hierzu wird die primäre gleichzeitige Radiochemotherapie (RCT) v. a. bei lokal fortgeschrittenen Kopf-Hals-Tumoren eingesetzt. Alternativ erfolgt die sequenzielle RCT, zunächst als Induktionschemotherapie durchgeführt und dann von einer alleinigen Radiatio oder einer RCT ergänzt. Zu beachten sind bei diesen Therapieansätzen die Funktionseinschränkungen im Bereich... περισσότερα »
Safety of Outpatient Thyroid and Parathyroid Surgery
Safety of Outpatient Thyroid and Parathyroid Surgery: A Propensity Score-Matched Study: Objective To test our hypothesis that general and thyroid surgery–specific complications, mortality, and postdischarge utilization for patients undergoing outpatient and inpatient thyroid and parathyroid surgery would not differ when outpatient status was defined as discharge within 8 hours of surgery completion. Study Design Retrospective observational cohort, 2008 to 2013. Setting Kaiser Permanente Northern California and Kaiser Permanente Southern California. Subjects and Methods We used ...περισσότερα »
Ist Radio(chemo)therapie wirklich der zukünftige Standard für die Behandlung von Oropharynxkarzinomen?
Ist Radio(chemo)therapie wirklich der zukünftige Standard für die Behandlung von Oropharynxkarzinomen?: ZusammenfassungDie Behandlung von Patienten mit einem Plattenepithelkarzinom des Oropharynx (OPSCC) erfordert eine interdisziplinäre Zusammenarbeit. Therapieziel ist neben der Tumorkontrolle der Funktions- und Organerhalt. Hierzu wird die primäre gleichzeitige Radiochemotherapie (RCT) v. a. bei lokal fortgeschrittenen Kopf-Hals-Tumoren eingesetzt. Alternativ erfolgt die sequenzielle RCT, zunächst als Induktionschemotherapie durchgeführt und dann von einer alleinigen Radiatio ode... περισσότερα »
Ballondilatation der Tuba auditiva bei Mittelohroperationen
Ballondilatation der Tuba auditiva bei Mittelohroperationen: Zusammenfassung HintergrundDie Entstehung von Mittelohrerkrankungen wird u. a. auf eine unzureichende Tubenfunktion zurückgeführt. In klinischen Fallserien wurde über die Ergebnisse der Ballondilatation zur Therapie von Tubendysfunktionen berichtet. ZielEs soll untersucht werden, ob Patienten mit geplanter Operation aufgrund einer chronischen Mittelohrerkrankung von einer zusätzlichen Ballondilatation der Tuba auditiva profitieren. MethodenIn eine randomisierte, kontrollierte, für Patienten und Untersucher verblinde... περισσότερα »
Epidemiology of Exertional Heat Illnesses in Youth, High School, and College Football.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Introduction: Data on exertional heat illness in youth football is limited and has not been compared across competition levels. Purpose: This study describes the epidemiology of EHI events in youth, high school (HS), and college football in the 2012-2014 seasons. Methods: One-hundred-and-eighteen youth teams (players aged 5-14 years), 96 HS programs (~14-18 years), and 34 college programs (~18-23 years) participated. During games and practices, athletic trainers recorded EHI events and athlete-exposures (AEs), defined as one athlete participating in one game/practice. We calculated ...περισσότερα »
Lower Integrated Muscle Protein Synthesis in Masters Compared to Younger Athletes.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Purpose: To compare the integrated muscle protein synthesis (MPS) rates of masters and younger triathletes over three consecutive days of intense endurance training. Recovery of cycling performance, following muscle-damaging running, was also compared between groups. Methods: Five masters (age, 53+/-2 y, V[spacing dot above]O2max, 55.7+/-6.9 mL[middle dot]kg-1[middle dot]min-1) and six younger (age, 27+/-2 y, V[spacing dot above]O2max, 62.3+/-1.5 mL[middle dot]kg-1[middle dot]min-1) trained triathletes volunteered for the study. Baseline skeletal muscle and saliva were initially sam...περισσότερα »
Age-Related Differences in OMNI-RPE Scale Validity in Youth: A Longitudinal Analysis.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Rating of perceived exertion (RPE) scales are used in exercise science research to assess perceptions of physical effort. RPE scale validity has been evaluated by assessing correlations between RPE and physiological indicators. Cross-sectional studies indicate that RPE scale validity improves with age; however, this has not been studied longitudinally. PURPOSE: To examine age-related trends in OMNI-RPE scale validity, using a longitudinal study design, and heart rate (HR) and oxygen uptake (VO2) as criterion measures. METHODS: Participants performed 11, five-minute activity trials a...περισσότερα »
A Systematic Review of the Energy Cost and Metabolic Intensity of Yoga.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Purpose: With the increasing popularity of Hatha yoga, it is important to understand the energy cost and metabolic equivalents (METs) of yoga practice within the context of the American College of Sports Medicine (ACSM) and the American Heart Association (AHA) physical activity guidelines. Methods: This systematic review evaluated the energy cost and metabolic intensity of yoga practice including yoga asanas (poses/postures) and pranayamas (breath exercises) measured by indirect calorimetry. The English Speaking Literature was surveyed via Pubmed using the general terms "yoga" and "... περισσότερα »
Mummified Thyroid Syndrome
American Journal of Roentgenology, Volume 206, Issue 4, Page 837-845, April 2016. from thyroid via a.lsfakia on Inoreader http://ift.tt/1Rk3QfB via IFTTT
Safety of Outpatient Thyroid and Parathyroid Surgery: A Propensity Score-Matched Study
Objective To test our hypothesis that general and thyroid surgery–specific complications, mortality, and postdischarge utilization for patients undergoing outpatient and inpatient thyroid and parathyroid surgery would not differ when outpatient status was defined as discharge within 8 hours of surgery completion. Study Design Retrospective observational cohort, 2008 to 2013. Setting Kaiser Permanente Northern California and Kaiser Permanente Southern California. Subjects and Methods We used a robust set of variables and propensity score methods to match 2362 patients undergo... περισσότερα »
Selective IT neurons are selective along many dimensions
Our visual abilities are unsurpassed because of a sophisticated code for objects located in the inferior temporal (IT) cortex. This code has remained a mystery because IT neurons show extremely diverse shape selectivity with no apparent organizing principle. Here, we show that there is an intrinsic component to selectivity in IT neurons. We tested IT neurons on distinct shapes and their parametric variations and asked whether neurons selective along one dimension were also selective along others. Selective neurons responded to fewer shapes and were narrowly tuned to local variatio...περισσότερα »
These new articles for The Journal of Clinical Endocrinology & Metabolism are available online
These new articles for The Journal of Clinical Endocrinology & Metabolism are available online ------------------------------ Early Release The Journal of Clinical Endocrinology & Metabolism ------------------------------ [image: Journal of Clinical Endocrinology & Metabolism masthead] ------------------------------ ------------------------------ The Journal of Clinical Endocrinology & Metabolism Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ Acute female hypogonadism alt... περισσότερα »
These new articles for Molecular Endocrinology are available online
These new articles for Molecular Endocrinology are available online ------------------------------ Early Release Molecular Endocrinology ------------------------------ [image: Molecular Endocrinology masthead] ------------------------------ ------------------------------ Molecular Endocrinology Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ Research Resource: Roles for Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) in Systems Metabolism Kathrina L. Marcelo,... περισσότερα »
Artemisitene activates the Nrf2-dependent antioxidant response and protects against bleomycin-induced lung injury Research
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 46 δευτερόλεπτα
The transcription factor nuclear factor erythroid 2–related factor 2 (Nrf2) is a crucial regulator of the cellular antioxidant response and xenobiotic metabolism. Activation of the Nrf2 signaling pathway has been demonstrated to confer protection against environmental insults and prevent disease or inhibit the progression of diseases related to oxidative stress. In an attempt to identify […]
These new articles for Endocrinology are available online
These new articles for Endocrinology are available online ------------------------------ Early Release Endocrinology ------------------------------ [image: Endocrinology masthead] ------------------------------ ------------------------------ Endocrinology Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ Bisphenol S Induces Adipogenesis in Primary Human Preadipocytes From Female Donors Jonathan G. Boucher, et al. | Endocrinology | Mar 22, 2016 ------------------------------ ... περισσότερα »
Radiation-induced translational control of gene expression
Changes in polysome-bound mRNA (translatome) are correlated closely with changes in the proteome in cells. Therefore, to better understand the processes mediating the response of glioblastoma (GBM) to ionizing radiation (IR), we used polysome profiling to define the IR-induced translatomes of a set of human glioblastoma stem-like cell (GSC) lines. Whereas cell line specificity accounted… Continue reading Radiation-induced translational control of gene expression
Reply: ‘Use of Acellular Dermal Matrix in Postmastectomy Breast Reconstruction: Are All Acellular Dermal Matrices Created Equal?’.
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Rfsx03 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/25lo1Dt via IFTTT
Early molecular events in lung cancer pathogenesis
The majority of cancer-related deaths in the United States and worldwide are attributed to lung cancer. There are more than 90 million smokers in the United States who represent a significant population at elevated risk for lung malignancy. In other epithelial tumors, it has been shown that if neoplastic lesions can be detected and treated… Continue reading Early molecular events in lung cancer pathogenesis
Reply: “Use of Acellular Dermal Matrix in Postmastectomy Breast Reconstruction: Are All Acellular Dermal Matrices Created Equal?”.
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XLPk42 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Rk0Yz7 via IFTTT
Soy effects on estrogen pathways in the pubertal breast
Endogenous estrogens influence mammary gland development during puberty and breast cancer risk during adulthood. Early-life exposure to dietary or environmental estrogens may alter estrogen-mediated processes. Soy foods contain phytoestrogenic isoflavones (IFs), which have mixed estrogen agonist/antagonist properties. Here, we evaluated mammary gland responses over time in pubertal female cynomolgus macaques fed diets containing either casein/lactalbumin… Continue reading Soy effects on estrogen pathways in the pubertal breast
The Effect of Abdominoplasty and Outcome of Rectus Fascia Plication on Health-Related Quality of Life in Post-Bariatric Surgery Patients.
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XLPiZP via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/25lo4it via IFTTT
Soy feeding prevents ethanol-mediated tumorigenesis
In this study, diethylnitrosamine-treated male mice were assigned to 3 groups: a 35% high fat ethanol liquid diet (EtOH) with casein as the protein source, the same EtOH liquid diet with soy protein isolate as the sole protein source (EtOH/SPI) and a chow group. EtOH feeding continued for 16 wks. As expected, EtOH increased the… Continue reading Soy feeding prevents ethanol-mediated tumorigenesis
What Is the Optimum Timing of Postmastectomy Radiotherapy in Two-Stage Prosthetic Reconstruction: Radiation to the Tissue Expander or Permanent Implant? Letter to The Editor.
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Rfsx01 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Rk0YiT via IFTTT
New tools for microglia in mouse and human Neuroscience
The specific function of microglia, the tissue resident macrophages of the brain and spinal cord, has been difficult to ascertain because of a lack of tools to distinguish microglia from other immune cells, thereby limiting specific immunostaining, purification, and manipulation. Because of their unique developmental origins and predicted functions, the… from #ORL-AlexandrosSfakianakis via simeraentaxei on… Continue reading New tools for microglia in mouse and human Neuroscience
Different ADM preparations, difference surgeons, different outcomes: what factors matter?.
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Rfsxx9 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/25lo4in via IFTTT
Reply: ‘Use of Acellular Dermal Matrix in Postmastectomy Breast Reconstruction: Are All Acellular Dermal Matrices Created Equal?’.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Rfsx03 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Reply: «Use of Acellular Dermal Matrix in Postmastectomy Breast Reconstruction: Are All Acellular Dermal Matrices Created Equal?».
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XLPk42 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
What Is the Optimum Timing of Postmastectomy Radiotherapy in Two-Stage Prosthetic Reconstruction: Radiation to the Tissue Expander or Permanent Implant? Letter to The Editor.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Rfsx01 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The Effect of Abdominoplasty and Outcome of Rectus Fascia Plication on Health-Related Quality of Life in Post-Bariatric Surgery Patients.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XLPiZP via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Different ADM preparations, difference surgeons, different outcomes: what factors matter?.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Rfsxx9 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
«Lifetime Costs of Prophylactic Mastectomies and Reconstruction versus Surveillance».
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XLPk3U via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Reply to: What Is the Optimum Timing of Postmastectomy Radiotherapy in Two-Stage Prosthetic Reconstruction: Radiation to the Tissue Expander or Permanent Implant? Letter to the editor, by Prof. Marco Klinger.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RfswZX via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Reply: Different ADM preparations, difference surgeons, different outcomes: what factors matter?.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XLPiJv via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Lifetime costs of prophylactic mastectomies and reconstruction versus surveillance.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Rfsxx5 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Radiation-induced translational control of gene expression
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Changes in polysome-bound mRNA (translatome) are correlated closely with changes in the proteome in cells. Therefore, to better understand the processes mediating the response of glioblastoma (GBM) to ionizing radiation (IR), we used polysome profiling to define the IR-induced translatomes of a set of human glioblastoma stem-like cell (GSC) lines. Whereas cell line specificity accounted […]
Early molecular events in lung cancer pathogenesis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The majority of cancer-related deaths in the United States and worldwide are attributed to lung cancer. There are more than 90 million smokers in the United States who represent a significant population at elevated risk for lung malignancy. In other epithelial tumors, it has been shown that if neoplastic lesions can be detected and treated […]
Soy effects on estrogen pathways in the pubertal breast
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Endogenous estrogens influence mammary gland development during puberty and breast cancer risk during adulthood. Early-life exposure to dietary or environmental estrogens may alter estrogen-mediated processes. Soy foods contain phytoestrogenic isoflavones (IFs), which have mixed estrogen agonist/antagonist properties. Here, we evaluated mammary gland responses over time in pubertal female cynomolgus macaques fed diets containing either casein/lactalbumin […]
Soy feeding prevents ethanol-mediated tumorigenesis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
In this study, diethylnitrosamine-treated male mice were assigned to 3 groups: a 35% high fat ethanol liquid diet (EtOH) with casein as the protein source, the same EtOH liquid diet with soy protein isolate as the sole protein source (EtOH/SPI) and a chow group. EtOH feeding continued for 16 wks. As expected, EtOH increased the […]
New tools for microglia in mouse and human Neuroscience
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The specific function of microglia, the tissue resident macrophages of the brain and spinal cord, has been difficult to ascertain because of a lack of tools to distinguish microglia from other immune cells, thereby limiting specific immunostaining, purification, and manipulation. Because of their unique developmental origins and predicted functions, the… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis […]
Diffusion MRI in detecting neuronal activity Neuroscience
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Functional MRI (fMRI) is widely used to study brain function in the neurosciences. Unfortunately, conventional fMRI only indirectly assesses neuronal activity via hemodynamic coupling. Diffusion fMRI was proposed as a more direct and accurate fMRI method to detect neuronal activity, yet confirmative findings have proven difficult to obtain. Given that… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis […]
Mutant huntingtin in BG disrupts motor sequences Neuroscience
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The basal ganglia (BG) promote complex sequential movements by helping to select elementary motor gestures appropriate to a given behavioral context. Indeed, Huntington’s disease (HD), which causes striatal atrophy in the BG, is characterized by hyperkinesia and chorea. How striatal cell loss alters activity in the BG and downstream motor… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis […]
ppGpp negatively impacts ribosome assembly Microbiology
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The stringent response is a survival mechanism used by bacteria to deal with stress. It is coordinated by the nucleotides guanosine tetraphosphate and pentaphosphate [(p)ppGpp], which interact with target proteins to promote bacterial survival. Although this response has been well characterized in proteobacteria, very little is known about the effectors… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis […]
Correction for Petroff and Libchaber, Hydrodynamics and collective behavior of the tethered bacterium Thiovulum majus Correction
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
APPLIED MATHEMATICS, MICROBIOLOGY Correction for “Hydrodynamics and collective behavior of the tethered bacterium Thiovulum majus,” by Alexander Petroff and Albert Libchaber, which appeared in issue 5, February 4, 2014, of Proc Natl Acad Sci USA (111:E537–E545; first published January 23, 2014; 10.1073/pnas.1322092111). The authors note that they have misidentified the… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis […]
Perceptual learning and prediction error Psychological and Cognitive Sciences
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Human perception is shaped by past experience on multiple timescales. Sudden and dramatic changes in perception occur when prior knowledge or expectations match stimulus content. These immediate effects contrast with the longer-term, more gradual improvements that are characteristic of perceptual learning. Despite extensive investigation of these two experience-dependent phenomena, there… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis […]
The Abbreviated Mental Test 4 for cognitive screening of older adults presenting to the Emergency Department.
Objectives: A commonly cited reason for the infrequent detection of cognitive impairment in the Emergency Department (ED) is the lack of an appropriate screening tool. The Abbreviated Mental Test 4 (AMT4) is a brief instrument recommended for cognitive screening of older adults in the ED. However, its exact utility in the detection of altered mental status in the ED is yet to be fully determined. Methods: The present study evaluated the ability of the AMT4 to identify impaired mental status in the ED, defined as positive scores on either the Confusion Assessment Method-ICU for delir... περισσότερα »
Characteristics and outcome of patients presenting to the emergency department after autologous/allogeneic stem cell transplantation.
Introduction: Hematopoietic stem cell transplantations are still associated with a high risk of complications. Here, we characterize patients after autologous or allogeneic transplantation presenting to the emergency department and investigate factors associated with patients' outcome after hospitalization. Methods: Patients who had previously undergone autologous or allogeneic stem cell transplantation were included in this study and data were collected retrospectively. We analyzed patients' characteristics and outcome, and identified factors associated with outcome. Results: A tot... περισσότερα »
Mutant huntingtin in BG disrupts motor sequences [Neuroscience]
The basal ganglia (BG) promote complex sequential movements by helping to select elementary motor gestures appropriate to a given behavioral context. Indeed, Huntington's disease (HD), which causes striatal atrophy in the BG, is characterized by hyperkinesia and chorea. How striatal cell loss alters activity in the BG and downstream motor... from Neurology via xlomafota13 on Inoreader http://ift.tt/1UEyk1A via IFTTT
PP2A methylation regulates A{beta} sensitivity [Neuroscience]
Elevated levels of the β-amyloid peptide (Aβ) are thought to contribute to cognitive and behavioral impairments observed in Alzheimer's disease (AD). Protein phosphatase 2A (PP2A) participates in multiple molecular pathways implicated in AD, and its expression and activity are reduced in postmortem brains of AD patients. PP2A is regulated by... from Neurology via xlomafota13 on Inoreader http://ift.tt/1S5bSsw via IFTTT
Network synchronization in hippocampal neurons [Physics]
Oscillatory activity is widespread in dynamic neuronal networks. The main paradigm for the origin of periodicity consists of specialized pacemaking elements that synchronize and drive the rest of the network; however, other models exist. Here, we studied the spontaneous emergence of synchronized periodic bursting in a network of cultured dissociated... from Neurology via xlomafota13 on Inoreader http://ift.tt/1LFT4U6 via IFTTT
PFC maturation and response inhibition [Neuroscience]
Executive functions including behavioral response inhibition mature after puberty, in tandem with structural changes in the prefrontal cortex. Little is known about how activity of prefrontal neurons relates to this profound cognitive development. To examine this, we tracked neuronal responses of the prefrontal cortex in monkeys as they transitioned from... from Neurology via xlomafota13 on Inoreader http://ift.tt/1LFPucD via IFTTT
Does Delay in Taking the American Board of Physical Medicine and Rehabilitation Certification Examinations Affect Passing Rates?.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Objectives: The objective of this study was to examine whether a delay in initially taking the Part I or Part II American Board of Physical Medicine and Rehabilitation certification examinations influences the score or passing rates of candidates and whether enrollment in a subspecialty fellowship influences performance on the Part II certification examination. Design: This was a retrospective review of first-time candidates taking the American Board of Physical Medicine and Rehabilitation initial certification examinations from 2010 to 2014. Results: Passing rates declined as candi... περισσότερα »
Cardiac Structure and Function in Elite Para-Cyclists with Spinal Cord Injury.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Purpose: We sought to explore the association between spinal cord injury (SCI) level on cardiac structure and function observed in elite para-cyclists. Methods: Cross-sectional echocardiographic data from 44 elite SCI hand-cyclists (39.8 +/- 9 years, 68% male/32% female) stratified by level of SCI (cervical, N = 9; T1-T5, N = 10; below T5, N = 25) and 19 non-SCI blind-visually impaired (BVI) tandem cyclists (32.4 +/- 7 years, 58% male / 42% female) were analyzed prior to the initiation of international competition. Results: Compared to non-SCI BVI cyclists, cervical SCI para-cyclist... περισσότερα »
How Do Candidates Perform When Repeating the American Board of Physical Medicine and Rehabilitation Certification Examinations?.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Objective: The objective of this study was to examine the likelihood of passing the Part I and Part II American Board of Physical Medicine and Rehabilitation (ABPMR) certification examinations after initially failing. Design: This was a retrospective review of candidates who had taken the ABPMR initial certification examinations between 2010 and 2014. Results: Passing rates declined markedly with repeated attempts for both part I and part II. Passing rates (mean [95% confidence interval]) for part I were first attempt, 90% (87%-92%); second attempt, 58% (52%-66%); third attempt, 41%...περισσότερα »
Fitness Is Independently Associated with Central Hemodynamics in Metabolic Syndrome.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Purpose: Fit individuals with metabolic syndrome (MetS) have lower mortality risk compared to less fit counterparts, despite the presence of obesity as a component of the syndrome. To understand the importance of fitness in treating this condition, we examined the association of fitness and fatness with central hemodynamic indices that are known independent predictors of cardiovascular events (CVEs). Methods: 68 individuals with MetS participated in this cross-sectional study. Central hemodynamics were calculated from radial applanation tonometry and comprised: aortic reservoir pres...περισσότερα »
Ultrasound Imaging of Persistent Median Artery and Veins in an Asymptomatic Patient With a Bifid Median Nerve.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
No abstract available from Rehabilitation via xlomafota13 on Inoreader http://ift.tt/25ljmBe via IFTTT
Protection from Muscle Damage in the Absence of Changes in Muscle Mechanical Behavior.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Introduction: The repeated bout effect characterises the protective adaptation following a single bout of unaccustomed eccentric exercise that induces muscle damage. Sarcomerogenesis and increased tendon compliance have been suggested as potential mechanisms for the repeated bout effect by preventing muscle fascicles from being stretched onto the descending limb of the length-tension curve (the region where sarcomere damage is thought to occur). In this study, evidence was sought for three possible mechanical changes that would support either the sarcomerogenesis or increased tendon ... περισσότερα »
Injury of the Ascending Reticular Activating System by Subfalcine Herniation After Subdural Hematoma: A Case Report.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
No abstract available from Rehabilitation via xlomafota13 on Inoreader http://ift.tt/1Zr2x3C via IFTTT
Ideomotor Apraxia Due to Injury of the Superior Longitudinal Fasciculus: A Case Report.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
We report on a patient who showed ideomotor apraxia due to injury of the superior longitudinal fasciculus following brain tumor and tumor bleeding, which was demonstrated by diffusion tensor tractography (DTT). A 60-yr-old, right-handed male patient underwent removal of brain meningioma and drainage of intraventricular hemorrhage and intracerebral hemorrhage in the left fronto-parietal lobe. At the time of DTT scanning (5 wk after onset), he was able to move the right upper extremity against gravity. The patient exhibited an intact ideational plan for motor performance. In addition, ... περισσότερα »
"Numb Chin Syndrome": Two Additional Cases of Mental Nerve Mononeuropathy Resulting from Metastasis and Infection: -A Redux!
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
No abstract available from Rehabilitation via xlomafota13 on Inoreader http://ift.tt/1Mlwpwd via IFTTT
Determining the Minimal Clinically Important Difference for 6-Minute Walk Distance in Fibromyalgia.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Objective: The aim of this study was to estimate the minimal clinically important difference (MCID) for 6-min walk distance (6MWD) in patients with fibromyalgia. Design: Data from a recently completed trial that included 187 patients who completed the 6-min walk test, Fibromyalgia Impact Questionnaire (FIQ), and Short-Form 36 (SF36) at 12 and 36 wks were used to examine longitudinal changes in 6MWD. An anchor-based approach that used linear regression analyses was used to determine the MCID for 6MWD, using the total FIQ score (FIQ-Total) and SF36-physical function domain as clinical...περισσότερα »
BLIND INJECTIONS: ETHICAL BUT NOT ELIGIBLE.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
No abstract available from Rehabilitation via xlomafota13 on Inoreader http://ift.tt/1MlwpfN via IFTTT
A genome-wide study of lipid response to fenofibrate in Caucasians: a combined analysis of the GOLDN and ACCORD studies.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Background: Fibrates are commonly prescribed for hypertriglyceridemia, but they also lower LDL cholesterol and increase HDL cholesterol. Large interindividual variations in lipid response suggest that some patients may benefit more than others and genetic studies could help identify such patients. Methods: We carried out the first genome-wide association study of lipid response to fenofibrate using data from two well-characterized clinical trials: the Genetics of Lipid Lowering Drugs and Diet Network (GOLDN) Study and the Action to Control Cardiovascular Risk in Diabetes (ACCORD) St... περισσότερα »
Ultrasound Guidance for Technically Challenging Intrathecal Baclofen Pump Refill: Three Cases and Procedure Description.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Intrathecal baclofen (ITB) therapy is a common treatment used to reduce spasticity due to neurologic disorders and injuries. A variety of factors can increase the difficulty of ITB pump refill. Excess subcutaneous fat overlying the pump, spasticity, suboptimal positioning, pump rotation or inversion, and scar formation over the reservoir fill port can create challenges during pump refill. As a result, multiple unsuccessful attempts at accessing the reservoir fill port can be painful and increase the risk of infection, particularly when repeat skin puncture is required. Blind attempt... περισσότερα »
A Systematic Review of the Energy Cost and Metabolic Intensity of Yoga.
Purpose: With the increasing popularity of Hatha yoga, it is important to understand the energy cost and metabolic equivalents (METs) of yoga practice within the context of the American College of Sports Medicine (ACSM) and the American Heart Association (AHA) physical activity guidelines. Methods: This systematic review evaluated the energy cost and metabolic intensity of… Continue reading A Systematic Review of the Energy Cost and Metabolic Intensity of Yoga.
Hemiplegic Shoulder Pain Reduces Quality of Life After Acute Stroke: A Prospective Population-Based Study.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Objective: Hemiplegic shoulder pain is a common complication of stroke. The primary aim of this study was to determine the association of hemiplegic shoulder pain with health-related quality of life at 12 months after first stroke in a population-based registry. The secondary aim was to identify other factors associated with health-related quality-of-life outcomes. Design: A prospective population-based study in a geographically defined region of Adelaide, South Australia was conducted. Multiple ascertainment methods identified all cases of stroke within a 12-month period. Objective ...περισσότερα »
Self-Selected and Maximal Walking Speeds Provide Greater Insight Into Fall Status Than Walking Speed Reserve Among Community-Dwelling Older Adults.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Objective: To determine the degree to which self-selected walking speed (SSWS), maximal walking speed (MWS), and walking speed reserve (WSR) are associated with fall status among community-dwelling older adults. Design: WS and 1-year falls history data were collected on 217 community-dwelling older adults (median age = 82, range 65-93 years) at a local outpatient PT clinic and local retirement communities and senior centers. WSR was calculated as a difference (WSRdiff = MWS - SSWS) and ratio (WSRratio = MWS/SSWS). Results: SSWS (P from Rehabilitation via xlomafota13 on Inoreader htt... περισσότερα »
Radial Extracorporeal Shock Wave Therapy in a Person With Advanced Osteonecrosis of the Femoral Head: A Case Report.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
This case report describes the first patient with avascular necrosis of the femoral head of Association Research Circulation Osseous stage IV, treated with radial extracorporeal shock wave therapy. By contrast, previous studies demonstrated the efficacy of a single treatment of focused extracorporeal shock wave therapy in improving pain and Harris Hip Scale in patients with avascular necrosis of the femoral head of Association Research Circulation Osseous stage I to III. The affected hip was treated with 6000 impulses of radial extracorporeal shock wave therapy at 10 Hz and an inten... περισσότερα »
«Numb Chin Syndrome»: Two Additional Cases of Mental Nerve Mononeuropathy Resulting from Metastasis and Infection: -A Redux!
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Mlwpwd via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Determining the Minimal Clinically Important Difference for 6-Minute Walk Distance in Fibromyalgia.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Objective: The aim of this study was to estimate the minimal clinically important difference (MCID) for 6-min walk distance (6MWD) in patients with fibromyalgia. Design: Data from a recently completed trial that included 187 patients who completed the 6-min walk test, Fibromyalgia Impact Questionnaire (FIQ), and Short-Form 36 (SF36) at 12 and 36 wks were […]
BLIND INJECTIONS: ETHICAL BUT NOT ELIGIBLE.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1MlwpfN via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Ultrasound Guidance for Technically Challenging Intrathecal Baclofen Pump Refill: Three Cases and Procedure Description.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Intrathecal baclofen (ITB) therapy is a common treatment used to reduce spasticity due to neurologic disorders and injuries. A variety of factors can increase the difficulty of ITB pump refill. Excess subcutaneous fat overlying the pump, spasticity, suboptimal positioning, pump rotation or inversion, and scar formation over the reservoir fill port can create challenges during […]
The Abbreviated Mental Test 4 for cognitive screening of older adults presenting to the Emergency Department.
Objectives: A commonly cited reason for the infrequent detection of cognitive impairment in the Emergency Department (ED) is the lack of an appropriate screening tool. The Abbreviated Mental Test 4 (AMT4) is a brief instrument recommended for cognitive screening of older adults in the ED. However, its exact utility in the detection of altered mental status in the ED is yet to be fully determined. Methods: The present study evaluated the ability of the AMT4 to identify impaired mental status in the ED, defined as positive scores on either the Confusion Assessment Method-ICU for delir... περισσότερα »
Characteristics and outcome of patients presenting to the emergency department after autologous/allogeneic stem cell transplantation.
Introduction: Hematopoietic stem cell transplantations are still associated with a high risk of complications. Here, we characterize patients after autologous or allogeneic transplantation presenting to the emergency department and investigate factors associated with patients' outcome after hospitalization. Methods: Patients who had previously undergone autologous or allogeneic stem cell transplantation were included in this study and data were collected retrospectively. We analyzed patients' characteristics and outcome, and identified factors associated with outcome. Results: A tot... περισσότερα »
Unpeeling the Evidence for the Banana Bag: Evidence-Based Recommendations for the Management of Alcohol-Associated Vitamin and Electrolyte Deficiencies in the ICU.
[image: wk-health-logo.gif] Objective: Patients with a chronic alcohol use disorder presenting to the ICU may be deficient in important vitamins and electrolytes and are often prescribed a "banana bag" as a reflexive standard of therapy. The difficulty of diagnosing Wernicke's encephalopathy in the critical care setting is reviewed. Furthermore, whether the contents and doses of micronutrients and electrolytes in standard banana bags meet the needs of critically ill patients with an alcohol use disorder is assessed based on available evidence. Data Source: MEDLINE/PubMed (1966 to J... περισσότερα »
Serum Amyloid P Contained in Alveolar Fluid From Patients With Acute Respiratory Distress Syndrome Mediates the Inhibition of Monocyte Differentiation into Fibrocyte.
[image: wk-health-logo.gif] Objective: Alveolar fibrocytes are monocyte-derived mesenchymal cells associated with poor prognosis in patients with acute respiratory distress syndrome. Our aims were to determine the following: 1) the ability of monocytes from acute respiratory distress syndrome patients to differentiate into fibrocytes; 2) the influence of the acute respiratory distress syndrome alveolar environment on fibrocyte differentiation; and 3) mediators involved in this modulation, focusing on serum amyloid P. Design: Experimental in vitro investigation. Setting: Two ICUs of... περισσότερα »
Risks and Benefits of Stress Ulcer Prophylaxis for Patients With Severe Sepsis.
[image: wk-health-logo.gif] Objectives: The Surviving Sepsis Campaign Guidelines recommend stress ulcer prophylaxis for patients with severe sepsis who have bleeding risks. Although sepsis has been considered as a risk factor for gastrointestinal bleeding, the effect of stress ulcer prophylaxis has not been studied in patients with severe sepsis. Furthermore, stress ulcer prophylaxis may be associated with an increased risk of hospital-acquired pneumonia or Clostridium -difficile infection. The aim of this study was to investigate the risks and benefits of stress ulcer prophylaxis ...περισσότερα »
Use of the GlideScope Ranger Video Laryngoscope for Emergency Intubation in the Prehospital Setting: A Randomized Control Trial.
[image: wk-health-logo.gif] Objectives: We sought to assess whether the GlideScope Ranger video laryngoscope may be a reliable alternative to direct laryngoscopy in the prehospital setting. Design: Multicenter, prospective, randomized, control trial with patient recruitment over 18 months. Setting: Four study centers operating physician-staffed rescue helicopters or ground units in Austria and Norway. Patients: Adult emergency patients requiring endotracheal intubation. Interventions: Airway management strictly following a prehospital algorithm. First and second intubation attempt ... περισσότερα »
Spontaneous Effort During Mechanical Ventilation: Maximal Injury With Less Positive End-Expiratory Pressure.
[image: wk-health-logo.gif] Objectives: We recently described how spontaneous effort during mechanical ventilation can cause "pendelluft," that is, displacement of gas from nondependent (more recruited) lung to dependent (less recruited) lung during early inspiration. Such transfer depends on the coexistence of more recruited (source) liquid-like lung regions together with less recruited (target) solid-like lung regions. Pendelluft may improve gas exchange, but because of tidal recruitment, it may also contribute to injury. We hypothesize that higher positive end-expiratory pressur... περισσότερα »
Hemiplegic Shoulder Pain Reduces Quality of Life After Acute Stroke: A Prospective Population-Based Study.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Objective: Hemiplegic shoulder pain is a common complication of stroke. The primary aim of this study was to determine the association of hemiplegic shoulder pain with health-related quality of life at 12 months after first stroke in a population-based registry. The secondary aim was to identify other factors associated with health-related quality-of-life outcomes. Design: A […]
Self-Selected and Maximal Walking Speeds Provide Greater Insight Into Fall Status Than Walking Speed Reserve Among Community-Dwelling Older Adults.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Objective: To determine the degree to which self-selected walking speed (SSWS), maximal walking speed (MWS), and walking speed reserve (WSR) are associated with fall status among community-dwelling older adults. Design: WS and 1-year falls history data were collected on 217 community-dwelling older adults (median age = 82, range 65-93 years) at a local outpatient PT […]
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