Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τετάρτη 30 Μαρτίου 2016

OtoRhinoLaryngology & Medicine,New Articles,March 30th,2016,a


Levels of immunoglobulin E specific to the major food allergen and chemokine (C-C motif) ligand (CCL)17/thymus and activation regulated chemokine and CCL22/macrophage-derived chemokine in infantile atopic dermatitis on Ishigaki Island

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Levels of immunoglobulin E specific to the major food allergen and chemokine (C-C motif) ligand (CCL)17/thymus and activation regulated chemokine and CCL22/macrophage-derived chemokine in infantile atopic dermatitis on Ishigaki Island: Abstract Atopic dermatitis (AD) is a multifactorial T-helper (Th)2-mediated skin disease frequently associated with elevated serum immunoglobulin (Ig)E and food allergy is also a Th2- and IgE-mediated adverse immunological reaction. Our previous study indicated the relation of egg allergy history and disease severity of AD. Thus, the purpose of the s... περισσότερα »

Five surgical maneuvers on nasal mucosa movement in cleft palate repair : (1) elevation of nasal mucosal off the maxilla; (2) dissection of nasal mucosa from soft palate musculature; (3) separation of nasal mucosa from palatine aponeurosis; (4) release of mucosa at the pterygopalatine junction; (5) mobilization of vomer flaps.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
– a cadaver study by Dennis C. Nguyen, Kamlesh B. Patel, Rajiv P. Parikh, Gary B. Skolnick, Albert S. Woo via Plastic, Reconstructive & Aesthetic Surgery This biomechanical study aims to characterize the nasal mucosa during palatoplasty, describing the soft tissue attachments at different zones and quantifying movement following their release. AbstractIntroduction This biomechanical study aims to characterize the nasal mucosa during palatoplasty, describing the soft tissue attachments at different zones and quantifying movement following their release. Methods Palatal nasal mucosa wa... περισσότερα »

Blood vessel occlusion in periburn tissue is secondary to erythrocyte aggregation and mitigated by a fibronectin-derived peptide that limits burn injury progression

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Blood vessel occlusion in periburn tissue is secondary to erythrocyte aggregation and mitigated by a fibronectin-derived peptide that limits burn injury progression: ABSTRACT Although vascular occlusion has long been noted in periburn tissue, the literature is inconsistent regarding the nature of the occlusion, with articles in the 1940s claiming that erythrocytes were the culprit and in the 1980s-90s that microthrombi were responsible. To better define the nature of vessel occlusion, we studied two porcine burn models, a hot comb horizontal injury model and a vertical injury progr... περισσότερα »

Defining a New Diagnostic Assessment Parameter for Wound Care: Elevated Protease Activity (EPA), an Indicator of Non-healing, for Targeted Protease-modulating Treatment

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Defining a New Diagnostic Assessment Parameter for Wound Care: Elevated Protease Activity (EPA), an Indicator of Non-healing, for Targeted Protease-modulating Treatment: [image: cover.gif?v=1&s=00eca2b4f3bb0b83a2b9cbac] Abstract It is widely accepted that elevated protease activity (EPA) in chronic wounds impedes healing. However, little progress has occurred in quantifying the level of protease activity that is detrimental for healing. The aim of this study was to determine the relationship between inflammatory protease activity and wound healing status, and to establish the leve... περισσότερα »

Understanding effects of topical ingredients on electrical measurement of skin hydration

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Understanding effects of topical ingredients on electrical measurement of skin hydration: Abstract Objective Methods which assess skin hydration based on changes in its electrical properties are widely used in both cosmetic and medical research. However the devices themselves often give results which are significantly different to each other. While some work has previously been carried out to try and understand what these devices are actually reading, it was based on a technique for measuring the devices’ responses to filter disks impregnated with different liquids, which could in ... περισσότερα »

Variation in the activities of late stage filaggrin processing enzymes, calpain-1 and bleomycin hydrolase, together with pyrrolidone carboxylic acid levels, corneocyte phenotypes and plasmin activities in non-sun exposed and sun-exposed facial stratum corneum of different ethnicities

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Variation in the activities of late stage filaggrin processing enzymes, calpain-1 and bleomycin hydrolase, together with pyrrolidone carboxylic acid levels, corneocyte phenotypes and plasmin activities in non-sun exposed and sun-exposed facial stratum corneum of different ethnicities: Abstract Background Knowledge of the ethnic differences and effects of photodamage on the relative amounts of natural moisturizing factor (NMF) together with filaggrin (FLG) processing enzymes in facial stratum corneum (SC) is limited. Our aim was to characterize the activities of calpain-1 (C-1), ble... περισσότερα »

Galectin-7 in the stratum corneum; a biomarker of the skin barrier function

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα
Galectin-7 in the stratum corneum; a biomarker of the skin barrier function: Abstract Objective Skin barrier disruption often occurs in diseased and damaged skin conditions such as atopic dermatitis (AD). We focused the galectin-7 protein (Gal-7) as a biomarker of skin condition and assessed whether the content of Gal-7 in stratum corneum (scGal-7) could be used as an indicator of skin barrier disruption and as an index of local skin symptoms in AD patients. Methods Alteration of Gal-7 expression levels in keratinocyte and scGal-7 contents after barrier disruption by sodium dodecyl... περισσότερα »

A mild hand cleanser, alkyl ether sulfate supplemented with alkyl ether carboxylic acid and alkyl glucoside, improves eczema on the hand and reduces the growth of Staphylococcus aureus on the skin surface

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
A mild hand cleanser, alkyl ether sulfate supplemented with alkyl ether carboxylic acid and alkyl glucoside, improves eczema on the hand and reduces the growth of Staphylococcus aureus on the skin surface: Abstract Objective Washing the hands using cleansers with antiseptic materials is the most popular method for hand hygiene and helps maintain health by preventing food poisoning and bacterial infections. However, repeated hand washing tends to induce eczema of the hand, such as dryness, cracking and erythema. Moreover, eczema on the hand leads to increased levels of *Staphylococcu...περισσότερα »

Clinical and three-dimensional analyses of nasal forms following secondary correction of cleft lip nose deformities using extended spreader cartilage graft with a cross-lap joint technique

Publication date: Available online 30 March 2016 Source:Journal of Oral and Maxillofacial Surgery Author(s): Norifumi Nakamura, Takako Okawachi, Kouzou Matsumoto, Namiko Kimura, Toshiro Kibe, Takao Fuchigami PurposeA surgical strategy for definitive cleft lip nasal correction that stably provides symmetrical and natural nasal forms has not been established to date. The purpose of this study was […]

“The Effect of Mesenchymal Stem Cells Application on The Distracted Bone Microstructure. (An Experimental Study)”

Publication date: Available online 29 March 2016 Source:Journal of Oral and Maxillofacial Surgery Author(s): Yasser N. El Hadidi, Marwa El Kassaby, Salah Abd El fatah Ahmed, Nahed Khamis PurposeDistraction osteogenesis (DO) is a surgical technique used to regenerate bone. The aim of this study was to improve the bone quality and quantity during DO by […]

Memory encoding may be influenced by expectation

Scientists propose an expectancy theory of memory that suggests we encode features of observed scenes in memory without necessarily linking them, unless we have a reason to do so. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22O4TPw via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Imaging predicts long-term effects in veterans with brain injury

Diffusion tensor imaging (DTI), a type of MRI, may be able to predict functional post-deployment outcomes for veterans who sustained mild traumatic brain injury (MTBI), or concussion, during… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Rqp8LY via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Can a video game company tame toxic behaviour?

Scientists are helping to stop antisocial behaviour in the world’s most popular online game. The next stop could be a kinder Internet. Nature 531 568 doi: 10.1038/531568a from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Rybvaf via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Food fortification for bone health in adulthood: a scoping review

Food fortification for bone health in adulthood: a scoping review European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.42 Authors: S J Whiting, W M Kohrt, M P Warren, M I Kraenzlin & J-P Bonjour from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1pK4J9U via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel […]

Modelling human height and weight: a Bayesian approach towards model comparison

Modelling human height and weight: a Bayesian approach towards model comparison European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.23 Authors: M Preising, A Suchomlinov, J Tutkuviene & C Aßmann from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/25w09wI via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Bioimpedance spectroscopy in the infant: effect of milk intake and extracellular fluid reservoirs on resistance measurements in term breastfed infants

Bioimpedance spectroscopy in the infant: effect of milk intake and extracellular fluid reservoirs on resistance measurements in term breastfed infants European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.26 Authors: Z Gridneva, A R Hepworth, L C Ward, C T Lai, P E Hartmann & D T Geddes from #Medicine-SfakianakisAlexandros via o.lakala70 […]

LMS tables for waist circumference and waist–height ratio in Colombian adults: analysis of nationwide data 2010

LMS tables for waist circumference and waist–height ratio in Colombian adults: analysis of nationwide data 2010 European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.46 Authors: R Ramírez-Vélez, J E Correa-Bautista, J Martínez-Torres, J F Méneses-Echavez, K González-Ruiz, E González-Jiménez, J Schmidt-RioValle & F Lobelo from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/25w09gi […]

Ethnic admixture affects diabetes risk in native Hawaiians: the Multiethnic Cohort

Ethnic admixture affects diabetes risk in native Hawaiians: the Multiethnic Cohort European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.32 Authors: G Maskarinec, Y Morimoto, S Jacobs, A Grandinetti, M K Mau & L N Kolonel from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1pK4ICT via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete […]

Microsurgical Reconstruction of Oncological Scalp Defects in the Elderly

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Microsurgical Reconstruction of Oncological Scalp Defects in the Elderly: The incidence of scalp tumors requiring radical excision increases with age. Free-flap surgery is the standard reconstructive option for large defects, however there is ongoing uncertainty about its safety in the elderly. We conducted a review of data and report on 19 cases older than 75 and 13 younger than 75 years. Data regarding patient demographics, types of tumors, surgery, size of defect, flaps used and prevalence of complications were analyzed. The patients in the elderly group had more accompanying med... περισσότερα »

Microsurgical Skill Acquisition In A One-day Introductory Course With Performance Evaluation Using Software Assisted Scoring System

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
Microsurgical Skill Acquisition In A One-day Introductory Course With Performance Evaluation Using Software Assisted Scoring System: Recent emphasis on microsurgical skill acquisition at an earlier stage of plastic surgery training has seen a shift towards objective competence based assessment. Yet no objective measures of spacing or alignment exist, with few validated models that assess ability. The authors propose a novel software analysis scoring system to objectively measure spacing, alignment and overall improvement in a one-day, introductory course setting.

Autologous plasma and its supporting role in fat graft survival

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
: a relevant vector to counteract resorption in lipofilling: Fat grafting has become a widespread technique for different reconstructive and aesthetic purposes. However, the disadvantage of fat grafting is the unpredictable resorption rate that often necessitates repetitive procedures, which in turn may have an impact on the morbidity. During the immediate, post-graft, ischemic period, cells survive due to the process of plasmatic imbibition. This biological phenomenon precedes the ingrowth of neo-capillaries that eventually will nourish the graft and bring it in a homeostatic equil... περισσότερα »

Adenylyl Cyclase-Associated Protein 1 in the Development of Head and Neck Squamous Cell Carcinomas.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Adenylyl Cyclase-Associated Protein 1 in the Development of Head and Neck Squamous Cell Carcinomas.* Bull Exp Biol Med. 2016 Mar 29; Authors: Kakurina GV, Kondakova IV, Cheremisina OV, Shishkin DA, Choinzonov EL Abstract We compared the content of adenylyl cyclase-associated protein 1 (CAP1) in the blood and tissues of patients with head and neck squamous cell carcinomas (with and without regional metastases), patients with chronic inflammatory diseases aggravated by laryngeal and laryngopharyngeal dysplasia, and healthy individuals. The data suggest that serum CAP1 concentrati... περισσότερα »

Serial re-expansion of pituitary gland is associated with endocrinological recovery.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Serial re-expansion of pituitary gland is associated with endocrinological recovery.* World Neurosurg. 2016 Mar 25; Authors: Cho KR, Hong SD, Hur KY, Kim ST, Seol HJ, Lee JI, Kong DS, Nam DH Abstract BACKGROUND: Minimizing pituitary dysfunction by preservation of the normal pituitary gland has a significant clinical impact on patient outcome after pituitary surgery. This study aimed to determine whether re-expansion of normal gland after surgery was related to endocrinological outcome. METHODS: From January 2012 to July 2014, 112 patients were eligible for this retrospective stud... περισσότερα »

Green synthesis of silver nanoparticles using Rheum palmatum root extract and their antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa.

Alexandros G. SfakianakisστοHead and NeckΠριν από 7 δευτερόλεπτα
*Green synthesis of silver nanoparticles using Rheum palmatum root extract and their antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa.* Artif Cells Nanomed Biotechnol. 2016 Mar 29;:1-8 Authors: Arokiyaraj S, Vincent S, Saravanan M, Lee Y, Oh YK, Kim KH Abstract In the present study, silver nanoparticles (AgNPs) were synthesized by using aqueous root extracts of Rheum palmatum and characterized by various spectroscopic methods. The nanoparticles were found to be in hexagonal and spherical shapes. The average particle size was found to be 121 ± 2 nm wi... περισσότερα »

Adenylyl Cyclase-Associated Protein 1 in the Development of Head and Neck Squamous Cell Carcinomas.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Adenylyl Cyclase-Associated Protein 1 in the Development of Head and Neck Squamous Cell Carcinomas.* Bull Exp Biol Med. 2016 Mar 29; Authors: Kakurina GV, Kondakova IV, Cheremisina OV, Shishkin DA, Choinzonov EL Abstract We compared the content of adenylyl cyclase-associated protein 1 (CAP1) in the blood and tissues of patients with head and neck squamous cell carcinomas (with and without regional metastases), patients with chronic inflammatory diseases aggravated by laryngeal and laryngopharyngeal dysplasia, and healthy individuals. The data suggest that serum CAP1 concentrati... περισσότερα »

Serial re-expansion of pituitary gland is associated with endocrinological recovery.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Serial re-expansion of pituitary gland is associated with endocrinological recovery.* World Neurosurg. 2016 Mar 25; Authors: Cho KR, Hong SD, Hur KY, Kim ST, Seol HJ, Lee JI, Kong DS, Nam DH Abstract BACKGROUND: Minimizing pituitary dysfunction by preservation of the normal pituitary gland has a significant clinical impact on patient outcome after pituitary surgery. This study aimed to determine whether re-expansion of normal gland after surgery was related to endocrinological outcome. METHODS: From January 2012 to July 2014, 112 patients were eligible for this retrospective stud... περισσότερα »

Green synthesis of silver nanoparticles using Rheum palmatum root extract and their antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Green synthesis of silver nanoparticles using Rheum palmatum root extract and their antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa.* Artif Cells Nanomed Biotechnol. 2016 Mar 29;:1-8 Authors: Arokiyaraj S, Vincent S, Saravanan M, Lee Y, Oh YK, Kim KH Abstract In the present study, silver nanoparticles (AgNPs) were synthesized by using aqueous root extracts of Rheum palmatum and characterized by various spectroscopic methods. The nanoparticles were found to be in hexagonal and spherical shapes. The average particle size was found to be 121 ± 2 nm wi... περισσότερα »

Aqueous two-phase system purification for superoxide dismutase induced by menadione from Phanerochaete chrysosporium.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Aqueous two-phase system purification for superoxide dismutase induced by menadione from Phanerochaete chrysosporium.* Artif Cells Nanomed Biotechnol. 2016 Mar 29;:1-9 Authors: Kavakcıoğlu B, Tongul B, Tarhan L Abstract In the present work, the partitioning behavior of menadione-induced superoxide dismutase (SOD; EC 1.15.1.1), an antioxidant enzyme that has various applications in the medical and cosmetic industries, from the white rot fungus Phanerochaete chrysosporium has been characterized on different types of aqueous two-phase systems (ATPSs) (poly(ethylene glycol)/polyprop... περισσότερα »

Long-term observation of lateral medullary infarction due to vertebral artery dissection assessed with multimodal neuroimaging.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
[image: http:--linkout.jstage.jst.go.jp-logo.gif] Related Articles *Long-term observation of lateral medullary infarction due to vertebral artery dissection assessed with multimodal neuroimaging.* J Nippon Med Sch. 2015;82(1):68-72 Authors: Nomura K, Mishina M, Okubo S, Suda S, Katsura K, Katayama Y Abstract A 33-year-old man presented with a lateral medullary infarction, vertigo, and nausea. At the time of hospital admission, he had Wallenberg syndrome. Although initial magnetic resonance imaging showed no abnormalities, subsequent diffusion-weighted magnetic resonance imaging sh... περισσότερα »

Anatomical Considerations to Prevent Facial Nerve Injury: Insights on Frontal Branch and Cervicofacial Trunk Nerve Anatomy in SMAS Face Lifts

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Anatomical Considerations to Prevent Facial Nerve Injury: Insights on Frontal Branch and Cervicofacial Trunk Nerve Anatomy in SMAS Face Lifts: * *[image: image]* Author Information *Department of Plastic and Reconstructive Surgery and Breast Unit, Catholic University of “Sacro Cuore”, University Hospital “A. Gemelli”, Rome, Italy* *Correspondence to Dr. Visconti, Via Pietro Adami, 22, 00168 Rome, Italy,joevisconti@hotmail.com* *Back to Top | Article Outline* Sir: *We read with interest the recent article by Dr. Roostaeian and colleagues regarding anatomic considerations to prevent ...περισσότερα »

Angiogenesis inhibitor; +25 new citations

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Angiogenesis inhibitor* These pubmed results were generated on 2016/03/30 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1olHpOS via IFTTT

Cutaneous primary B-cell lymphomas: from diagnosis to treatment.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Cutaneous primary B-cell lymphomas: from diagnosis to treatment.* An Bras Dermatol. 2015 Sep-Oct;90(5):687-706 Authors: Lima M Abstract Primary cutaneous B-cell lymphomas are a heterogeneous group of mature B-cells neoplasms with tropism for the skin, whose biology and clinical course differ significantly from the equivalent nodal lymphomas. The most indolent forms comprise the primary cutaneous marginal zone and follicle center B-cell lymphomas that despite the excellent prognosis have cutaneous recurrences very commonly. The most aggressive forms include the primary cutaneous ... περισσότερα »

Predicting Prognosis in Chronic Lymphocytic Leukemia in the Contemporary Era.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Predicting Prognosis in Chronic Lymphocytic Leukemia in the Contemporary Era.* JAMA Oncol. 2015 Oct;1(7):965-74 Authors: Nabhan C, Raca G, Wang YL Abstract IMPORTANCE: Next-generation sequencing has identified new genetic markers that have altered prognosis for patients with chronic lymphocytic leukemia (CLL) at diagnosis. Understanding the significance of these prognostic indicators and recognizing their potential impact on treatment selection and patients' outcomes is critical for clinicians and investigators. OBJECTIVE: To review novel prognostic factors at CLL diagnosis that ...περισσότερα »

Lesion on the Plantar Foot. Shingles.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Lesion on the Plantar Foot. Shingles.* JAMA Oncol. 2015 Sep;1(6):833-4 Authors: Almazan TH, Zain J, Jung JY PMID: 26181141 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1fPqP6C via IFTTT

Atypical Imaging Findings in an Immunocompetent Patient. Primary central nervous system lymphoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Atypical Imaging Findings in an Immunocompetent Patient. Primary central nervous system lymphoma.* JAMA Oncol. 2015 May;1(2):247-8 Authors: Savage J, Quint D PMID: 26181031 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1MSlVzx via IFTTT

Primary extranodal marginal zone lymphoma of the endometrium: report of four cases and review of literature.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Primary extranodal marginal zone lymphoma of the endometrium: report of four cases and review of literature.* Int J Clin Exp Pathol. 2015;8(3):3036-44 Authors: Tahmasebi FC, Roy S, Kolitz JE, Sen F, Laser J, Zhang X Abstract Primary extranodal marginal zone lymphoma of the endometrium (PEMZL-EM) is exceedingly rare and has not been well characterized. Herein, we study the clinicopathological, cytogenetic and molecular features of four cases, the largest case series reported to date. The median age of the four patients was 59 years. Clinical presentations included abnormal vaginal... περισσότερα »

Inhibition of Oncogenic Transcription Factor REL by the Natural Product Derivative Calafianin Monomer 101 Induces Proliferation Arrest and Apoptosis in Human B-Lymphoma Cell Lines.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Inhibition of Oncogenic Transcription Factor REL by the Natural Product Derivative Calafianin Monomer 101 Induces Proliferation Arrest and Apoptosis in Human B-Lymphoma Cell Lines.* Molecules. 2015;20(5):7474-94 Authors: Yeo AT, Chennamadhavuni S, Whitty A, Porco JA, Gilmore TD Abstract Increased activity of transcription factor NF-κB has been implicated in many B-cell lymphomas. We investigated effects of synthetic compound calafianin monomer (CM101) on biochemical and biological properties of NF-κB. In human 293 cells, CM101 selectively inhibited DNA binding by overexpressed N... περισσότερα »

Outcomes of Clostridium difficile infection in hospitalized leukemia patients: a nationwide analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Outcomes of Clostridium difficile infection in hospitalized leukemia patients: a nationwide analysis.* Infect Control Hosp Epidemiol. 2015 Jul;36(7):794-801 Authors: Luo R, Greenberg A, Stone CD Abstract BACKGROUND The incidence of Clostridium difficile infection (CDI) has increased among hospitalized patients and is a common complication of leukemia. We investigated the risks for and outcomes of CDI in hospitalized leukemia patients. METHODS Adults with a primary diagnosis of leukemia were extracted from the United States Nationwide Inpatient Sample database, 2005-2011. The pri...περισσότερα »

Tumour targeting and radiation dose of radioimmunotherapy with (90)Y-rituximab in CD20+ B-cell lymphoma as predicted by (89)Zr-rituximab immuno-PET: impact of preloading with unlabelled rituximab.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Tumour targeting and radiation dose of radioimmunotherapy with (90)Y-rituximab in CD20+ B-cell lymphoma as predicted by (89)Zr-rituximab immuno-PET: impact of preloading with unlabelled rituximab.* Eur J Nucl Med Mol Imaging. 2015 Jul;42(8):1304-14 Authors: Muylle K, Flamen P, Vugts DJ, Guiot T, Ghanem G, Meuleman N, Bourgeois P, Vanderlinden B, van Dongen GA, Everaert H, Vaes M, Bron D Abstract PURPOSE: To compare using immuno-PET/CT the distribution of (89)Zr-labelled rituximab without and with a preload of unlabelled rituximab to assess the impact of preloading with unlabelled... περισσότερα »

[Synchronous hepatocellular carcinoma and B-cell non-Hodgkin's lymphoma in chronic hepatitis C patient].

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*[Synchronous hepatocellular carcinoma and B-cell non-Hodgkin's lymphoma in chronic hepatitis C patient].* Korean J Gastroenterol. 2014 Sep 25;64(3):168-72 Authors: Lee SI, Heo NY, Park SH, Joo YD, Kim IH, Park JI, Kim JY, Kim SH, Shim HK Abstract Hepatitis C virus (HCV) is one of the main viral causes of hepatocellular carcinoma (HCC) and is associated with lymphoproliferative disorder such as non-Hodgkin's lymphoma (NHL). However, there are only few case reports on concomitantly induced NHL and HCC by HCV. Herein, we report a case of synchronous NHL and HCC in a patient with ch... περισσότερα »

upper respiratory tract infection; +55 new citations

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
55 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2016/03/30 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/22O3Ejg via IFTTT

Monocyte Subsets and Related Chemokines in Carotid Artery Stenosis and Ischemic Stroke.

Alexandros G. SfakianakisστοHead and NeckΠριν από 8 δευτερόλεπτα
*Monocyte Subsets and Related Chemokines in Carotid Artery Stenosis and Ischemic Stroke.* Int J Mol Sci. 2016;17(4) Authors: Grosse GM, Schulz-Schaeffer WJ, Teebken OE, Schuppner R, Dirks M, Worthmann H, Lichtinghagen R, Maye G, Limbourg FP, Weissenborn K Abstract Carotid stenosis (CS) is an important cause of ischemic stroke. However, reliable markers for the purpose of identification of high-risk, so-called vulnerable carotid plaques, are still lacking. Monocyte subsets are crucial players in atherosclerosis and might also contribute to plaque rupture. In this study we, therefo...περισσότερα »

Adipose Stem Cells Isolated from Excised Burned Tissue

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
* Is There Potential for Clinical Use?: * Author Information *Division of Plastic Surgery, Rutgers New Jersey Medical School, Newark, N.J.* *The Burn Center, Saint Barnabas Medical Center, Livingston, N.J.* *Division of Plastic Surgery, Rutgers New Jersey Medical School, Newark, N.J.* *Correspondence to Dr. Condé-Green, Division of Plastic Surgery, Rutgers New Jersey Medical School, 140 Bergen Street, Suite E1620, Newark, N.J. 07103,acondegreen@yahoo.com* *Back to Top | Article Outline* Sir: *Recent studies have shown the benefits of autologous fat grafting and adipose-derived rege...περισσότερα »

The Ideal Human Proportions and Man as a Measure of All Things

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
*Leonardo da Vinci’s Vitruvian Man* Author Information *Department of Plastic, Reconstructive, Aesthetic, and Hand Surgery, Basel University Hospital, Basel, Switzerland* *Correspondence to Dr. Schaefer, Plastic, Reconstructive, Aesthetic, and Hand Surgery, Basel University Hospital, Spitalstrasse 21, 4031 Basel, Switzerland, dirk.schaefer@usb.ch* *Back to Top | Article Outline* Sir: *We read with great interest the correspondence between Khouri1,2 and Perdanasari et al.3 about how to reach greatness in plastic surgery. We would like to acknowledge Perdanasari et al.3 for citing Pro...περισσότερα »

A Practical Approach to Rhinoplasty

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
A Practical Approach to Rhinoplasty: Learning Objectives: After studying this article, the participant should be able to: 1. Understand both preoperative aesthetic and functional assessment of the rhinoplasty patient. 2. Develop an operative plan to address aesthetic goals while preserving/improving nasal airway function. Summary: Rhinoplasty continues to be one of the most commonly performed aesthetic surgical procedures. Over the past 25 years, the open approach has increased in popularity and is the focus of this article. The principles for successful rhinoplasty include comprehe... περισσότερα »

The Evolution of Free Vascularized Bone Transfer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
A 40-Year Experience: [image: image]Background: The first successful free vascularized bone flap was performed on June 1, 1974 (and reported in 1975), using the fibula. This was followed by the iliac crest based on the superficial circumflex iliac artery in 1975 and then the deep circumflex iliac artery in 1978. Methods: A total of 384 transfers using fibula (n = 198), iliac crest (n = 180), radius (n = 4), rib (n = 1), and metatarsal (n = 1) were used between June of 1974 and June of 2014 for reconstruction of the mandible (n = 267), maxilla (n = 20), clavicle (n = 1), humerus (... περισσότερα »

Endogenous hydrogen sulfide is involved in osteogenic differentiation in human periodontal ligament cells

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα
Publication date: August 2016 *Source:*Archives of Oral Biology, Volume 68 Author(s): Sheng-Dan Cen, Wen-Bin Yu, Man-Man Ren, Li-Jiao Chen, Chao-Fan Sun, Zhi-Li Ye, Hui Deng, Rong-Dang Hu ObjectiveEndogenous hydrogen sulfide (H2S) has recently emerged as an important intracellular gaseous signaling molecule within cellular systems. Endogenous H2S is synthesized from l-cysteine via cystathionine β-synthase and cystathionine γ-lyase and it regulates multiple signaling pathways in mammalian cells. Indeed, aberrant H2S levels have been linked to defects in bone formation in experimental...περισσότερα »

Rare radiological pattern of diffuse esophageal spasm.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Rare radiological pattern of diffuse esophageal spasm.* West J Emerg Med. 2015 May;16(3):426-7 Authors: Lipe DN, Borden N PMID: 25987921 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1q1objc via IFTTT

Achalasia secondary to lung adenocarcinoma.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα
[image: http:--kjim.org-image-kjim_icon.gif] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Achalasia secondary to lung adenocarcinoma.* Korean J Intern Med. 2015 Mar;30(2):250-1 Authors: Can B, Balli F, Korkmaz U, Yilmaz H, Can FI, Celebi A PMID: 25750568 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1Swpgsd via IFTTT

Modern Combat Trauma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
The Role of Military Plastic Surgeons in the Management of Modern Combat Trauma: An Analysis of 645 Cases: Background: Plastic surgery has historically been linked to war. Between 2008 and the end of combat operations in Afghanistan in 2014, British military plastic surgeons formed part of the multinational military surgical team at the Role 3 Medical Treatment Facility, Camp Bastion, Helmand Province. The present study aimed to analyze the activity of these surgeons objectively and to determine the utility of their deployment. Methods: Data were gathered prospectively from four per... περισσότερα »

Poland syndrome is a congenital anomaly of pectoralis muscles, breast, chest, and upper arm.Body Image Disorders and Surgical Timing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Body Image Disorders and Surgical Timing in Patients Affected by Poland Syndrome: Data Analysis of 58 Case Studies: Background: Poland syndrome is a congenital anomaly of pectoralis muscles, breast, chest, and upper arm. Several studies have reported that patients affected by chest wall deformities often experience body image disorders and decreased quality of life. Cosmetic corrective surgery is generally postponed until physical development is achieved, and latissimus dorsi flap surgery is usually suggested. This study aims to propose a new surgical timing for these patients. Met...περισσότερα »

Surgical Management of Obstructive Sleep Apnea

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Surgical Management of Obstructive Sleep Apnea: [image: image]Summary: Surgical management of snoring and obstructive sleep apnea is indicated when a surgically correctable abnormality is believed to be the source of the problem. Many patients opt for surgical treatment after noninvasive forms of treatment have been proven ineffective or difficult to tolerate. With increasing frequency, functional rhinoplasty, septoplasty, turbinoplasty, palatal surgery, and orthognathic surgery are being used in the management of snoring and obstructive sleep apnea. Plastic surgeons’ experience w...περισσότερα »

Emergence of Secondary Trigger Sites after Primary Migraine Surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Emergence of Secondary Trigger Sites after Primary Migraine Surgery: Background: Surgical decompression of a migraine headache may unmask headaches originating from secondary sites. A retrospective chart review investigated the incidence and characteristics of secondary trigger sites to identify clinical patterns that could aid in predicting and perhaps reducing postoperative migraines. Methods: One hundred eighty-five charts for migraine patients who underwent surgery at the senior author’s (B.G.) practice were reviewed. Sites from which migraine headaches initiated or occurred ind... περισσότερα »

Anatomical Considerations to Prevent Facial Nerve Injury

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
*Insights on Frontal Branch and Cervicofacial Trunk Nerve Anatomy in SMAS Face Lifts: * *[image: image]* Author Information *Department of Plastic and Reconstructive Surgery and Breast Unit, Catholic University of “Sacro Cuore”, University Hospital “A. Gemelli”, Rome, Italy* *Correspondence to Dr. Visconti, Via Pietro Adami, 22, 00168 Rome, Italy,joevisconti@hotmail.com* *Back to Top | Article Outline* Sir: *We read with interest the recent article by Dr. Roostaeian and colleagues regarding anatomic considerations to prevent facial nerve injury.1 The authors provided a state-of-a... περισσότερα »

Lengthening Temporalis Myoplasty for Single-Stage Smile Reconstruction in Children with Facial Paralysis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Lengthening Temporalis Myoplasty for Single-Stage Smile Reconstruction in Children with Facial Paralysis: [image: image]Background: Free muscle transfer for dynamic smile reanimation in facial paralysis is not always predictable with regard to cosmesis. Hospital stays range from 5 to 7 days. Prolonged operative times, longer hospital stays, and excessive cheek bulk are associated with free flap options. Lengthening temporalis myoplasty offers single-stage smile reanimation with theoretical advantages over free tissue transfer. Methods: From 2012 to 2014, 18 lengthening temporalis my...περισσότερα »

Aqueous two-phase system purification for superoxide dismutase induced by menadione from Phanerochaete chrysosporium.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*Aqueous two-phase system purification for superoxide dismutase induced by menadione from Phanerochaete chrysosporium.* Artif Cells Nanomed Biotechnol. 2016 Mar 29;:1-9 Authors: Kavakcıoğlu B, Tongul B, Tarhan L Abstract In the present work, the partitioning behavior of menadione-induced superoxide dismutase (SOD; EC 1.15.1.1), an antioxidant enzyme that has various applications in the medical and cosmetic industries, from the white rot fungus Phanerochaete chrysosporium has been characterized on different types of aqueous two-phase systems (ATPSs) (poly(ethylene glycol)/polyprop... περισσότερα »

Long-term observation of lateral medullary infarction due to vertebral artery dissection assessed with multimodal neuroimaging.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
[image: http:--linkout.jstage.jst.go.jp-logo.gif] Related Articles *Long-term observation of lateral medullary infarction due to vertebral artery dissection assessed with multimodal neuroimaging.* J Nippon Med Sch. 2015;82(1):68-72 Authors: Nomura K, Mishina M, Okubo S, Suda S, Katsura K, Katayama Y Abstract A 33-year-old man presented with a lateral medullary infarction, vertigo, and nausea. At the time of hospital admission, he had Wallenberg syndrome. Although initial magnetic resonance imaging showed no abnormalities, subsequent diffusion-weighted magnetic resonance imaging sh... περισσότερα »

Angiogenesis inhibitor; +25 new citations

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Angiogenesis inhibitor* These pubmed results were generated on 2016/03/30 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1olHpOS via IFTTT

Cutaneous primary B-cell lymphomas: from diagnosis to treatment.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*Cutaneous primary B-cell lymphomas: from diagnosis to treatment.* An Bras Dermatol. 2015 Sep-Oct;90(5):687-706 Authors: Lima M Abstract Primary cutaneous B-cell lymphomas are a heterogeneous group of mature B-cells neoplasms with tropism for the skin, whose biology and clinical course differ significantly from the equivalent nodal lymphomas. The most indolent forms comprise the primary cutaneous marginal zone and follicle center B-cell lymphomas that despite the excellent prognosis have cutaneous recurrences very commonly. The most aggressive forms include the primary cutaneous ... περισσότερα »

Predicting Prognosis in Chronic Lymphocytic Leukemia in the Contemporary Era.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*Predicting Prognosis in Chronic Lymphocytic Leukemia in the Contemporary Era.* JAMA Oncol. 2015 Oct;1(7):965-74 Authors: Nabhan C, Raca G, Wang YL Abstract IMPORTANCE: Next-generation sequencing has identified new genetic markers that have altered prognosis for patients with chronic lymphocytic leukemia (CLL) at diagnosis. Understanding the significance of these prognostic indicators and recognizing their potential impact on treatment selection and patients' outcomes is critical for clinicians and investigators. OBJECTIVE: To review novel prognostic factors at CLL diagnosis that ...περισσότερα »

Lesion on the Plantar Foot. Shingles.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*Lesion on the Plantar Foot. Shingles.* JAMA Oncol. 2015 Sep;1(6):833-4 Authors: Almazan TH, Zain J, Jung JY PMID: 26181141 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1fPqP6C via IFTTT

Atypical Imaging Findings in an Immunocompetent Patient. Primary central nervous system lymphoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*Atypical Imaging Findings in an Immunocompetent Patient. Primary central nervous system lymphoma.* JAMA Oncol. 2015 May;1(2):247-8 Authors: Savage J, Quint D PMID: 26181031 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1MSlVzx via IFTTT

Primary extranodal marginal zone lymphoma of the endometrium: report of four cases and review of literature.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*Primary extranodal marginal zone lymphoma of the endometrium: report of four cases and review of literature.* Int J Clin Exp Pathol. 2015;8(3):3036-44 Authors: Tahmasebi FC, Roy S, Kolitz JE, Sen F, Laser J, Zhang X Abstract Primary extranodal marginal zone lymphoma of the endometrium (PEMZL-EM) is exceedingly rare and has not been well characterized. Herein, we study the clinicopathological, cytogenetic and molecular features of four cases, the largest case series reported to date. The median age of the four patients was 59 years. Clinical presentations included abnormal vaginal... περισσότερα »

Inhibition of Oncogenic Transcription Factor REL by the Natural Product Derivative Calafianin Monomer 101 Induces Proliferation Arrest and Apoptosis in Human B-Lymphoma Cell Lines.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*Inhibition of Oncogenic Transcription Factor REL by the Natural Product Derivative Calafianin Monomer 101 Induces Proliferation Arrest and Apoptosis in Human B-Lymphoma Cell Lines.* Molecules. 2015;20(5):7474-94 Authors: Yeo AT, Chennamadhavuni S, Whitty A, Porco JA, Gilmore TD Abstract Increased activity of transcription factor NF-κB has been implicated in many B-cell lymphomas. We investigated effects of synthetic compound calafianin monomer (CM101) on biochemical and biological properties of NF-κB. In human 293 cells, CM101 selectively inhibited DNA binding by overexpressed N... περισσότερα »

Outcomes of Clostridium difficile infection in hospitalized leukemia patients: a nationwide analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*Outcomes of Clostridium difficile infection in hospitalized leukemia patients: a nationwide analysis.* Infect Control Hosp Epidemiol. 2015 Jul;36(7):794-801 Authors: Luo R, Greenberg A, Stone CD Abstract BACKGROUND The incidence of Clostridium difficile infection (CDI) has increased among hospitalized patients and is a common complication of leukemia. We investigated the risks for and outcomes of CDI in hospitalized leukemia patients. METHODS Adults with a primary diagnosis of leukemia were extracted from the United States Nationwide Inpatient Sample database, 2005-2011. The pri...περισσότερα »

Tumour targeting and radiation dose of radioimmunotherapy with (90)Y-rituximab in CD20+ B-cell lymphoma as predicted by (89)Zr-rituximab immuno-PET: impact of preloading with unlabelled rituximab.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*Tumour targeting and radiation dose of radioimmunotherapy with (90)Y-rituximab in CD20+ B-cell lymphoma as predicted by (89)Zr-rituximab immuno-PET: impact of preloading with unlabelled rituximab.* Eur J Nucl Med Mol Imaging. 2015 Jul;42(8):1304-14 Authors: Muylle K, Flamen P, Vugts DJ, Guiot T, Ghanem G, Meuleman N, Bourgeois P, Vanderlinden B, van Dongen GA, Everaert H, Vaes M, Bron D Abstract PURPOSE: To compare using immuno-PET/CT the distribution of (89)Zr-labelled rituximab without and with a preload of unlabelled rituximab to assess the impact of preloading with unlabelled... περισσότερα »

[Synchronous hepatocellular carcinoma and B-cell non-Hodgkin's lymphoma in chronic hepatitis C patient].

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*[Synchronous hepatocellular carcinoma and B-cell non-Hodgkin's lymphoma in chronic hepatitis C patient].* Korean J Gastroenterol. 2014 Sep 25;64(3):168-72 Authors: Lee SI, Heo NY, Park SH, Joo YD, Kim IH, Park JI, Kim JY, Kim SH, Shim HK Abstract Hepatitis C virus (HCV) is one of the main viral causes of hepatocellular carcinoma (HCC) and is associated with lymphoproliferative disorder such as non-Hodgkin's lymphoma (NHL). However, there are only few case reports on concomitantly induced NHL and HCC by HCV. Herein, we report a case of synchronous NHL and HCC in a patient with ch... περισσότερα »

upper respiratory tract infection; +55 new citations

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
55 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2016/03/30 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/22O3Ejg via IFTTT

Monocyte Subsets and Related Chemokines in Carotid Artery Stenosis and Ischemic Stroke.

Alexandros G. SfakianakisστοHead and NeckΠριν από 13 δευτερόλεπτα
*Monocyte Subsets and Related Chemokines in Carotid Artery Stenosis and Ischemic Stroke.* Int J Mol Sci. 2016;17(4) Authors: Grosse GM, Schulz-Schaeffer WJ, Teebken OE, Schuppner R, Dirks M, Worthmann H, Lichtinghagen R, Maye G, Limbourg FP, Weissenborn K Abstract Carotid stenosis (CS) is an important cause of ischemic stroke. However, reliable markers for the purpose of identification of high-risk, so-called vulnerable carotid plaques, are still lacking. Monocyte subsets are crucial players in atherosclerosis and might also contribute to plaque rupture. In this study we, therefo...περισσότερα »

Complete ossification of the stylohyoid chain as cause of Eagle's syndrome: a very rare case report.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
Related Articles *Complete ossification of the stylohyoid chain as cause of Eagle's syndrome: a very rare case report.* J Contemp Dent Pract. 2014 Jul-Aug;15(4):500-5 Authors: Guimarães AS, Pozza DH, de Castro IC, Galdames IC, Palla S Abstract AIM: To report on a patient with Eagle's syndrome with a complete and very large ossification of the stylohyoid complex on the right side that to our best knowledge has never been published previously. BACKGROUND: Eagle's syndrome is characterized by a set of symptoms that are caused by the irritation of the neurovascular and soft-tissues ca...περισσότερα »

Smoking as an independent determinant of Barrett's esophagus and, to a lesser degree, of reflux esophagitis.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *Smoking as an independent determinant of Barrett's esophagus and, to a lesser degree, of reflux esophagitis.* Cancer Causes Control. 2015 Mar;26(3):419-29 Authors: Filiberti R, Fontana V, De Ceglie A, Blanchi S, Grossi E, Della Casa D, Lacchin T, De Matthaeis M, Ignomirelli O, Cappiello R, Foti M, Laterza F, Annese V, Iaquinto G, Conio M Abstract PURPOSE: To evaluate the role of smoking in Barrett's esophagus (BE) and erosive esophagitis (E) compared to endoscopic controls with no BE or E. Smoking is considered a... περισσότερα »

The incidence of healthcare use, ill health and mortality in adults with intellectual disabilities and mealtime support needs.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *The incidence of healthcare use, ill health and mortality in adults with intellectual disabilities and mealtime support needs.* J Intellect Disabil Res. 2015 Jul;59(7):638-52 Authors: Perez CM, Ball SL, Wagner AP, Clare IC, Holland AJ, Redley M Abstract BACKGROUND: Adults with intellectual disabilities (ID) experience a wide range of eating, drinking and/or swallowing (EDS) problems, for which they receive diverse mealtime support interventions. Previous research has estimated that dysphagia (difficulty swallowing... περισσότερα »

Correlation of Stomatitis and Cutaneous Toxicity With Clinical Outcome in Patients With Metastatic Renal-Cell Carcinoma Treated With Everolimus.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
*Correlation of Stomatitis and Cutaneous Toxicity With Clinical Outcome in Patients With Metastatic Renal-Cell Carcinoma Treated With Everolimus.* Clin Genitourin Cancer. 2016 Feb 23; Authors: Conteduca V, Santoni M, Medri M, Scarpi E, Burattini L, Lolli C, Rossi L, Savini A, Berardi R, Stanganelli I, Cascinu S, De Giorgi U Abstract BACKGROUND: In clinical practice, discontinuation or dose reduction of everolimus may be induced not only by grade 3 or 4 toxicities but also by prolonged grade 2 toxicities, such as stomatitis and/or cutaneous toxicity, which share some pathogenetic m...περισσότερα »

Candida/Candida biofilms. First description of dual-species Candida albicans/C. rugosa biofilm.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
*Candida/Candida biofilms. First description of dual-species Candida albicans/C. rugosa biofilm.* Fungal Biol. 2016 Apr;120(4):530-7 Authors: Martins CH, Pires RH, Cunha AO, Pereira CA, Singulani Jde L, Abrão F, Moraes Td, Mendes-Giannini MJ Abstract Denture liners have physical properties that favour plaque accumulation and colonization by Candida species, irritating oral tissues and causing denture stomatitis. To isolate and determine the incidence of oral Candida species in dental prostheses, oral swabs were collected from the dental prostheses of 66 patients. All the strains ...περισσότερα »

Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen.

Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen.* Acta Neuropathol. 2016 Mar 29; Authors: Kinzel S, Lehmann-Horn K, Torke S, Häusler D, Winkler A, Stadelmann C, Payne N, Feldmann L, Saiz A, Reindl M, Lalive PH, Bernard CC, Brück W, Weber MS Abstract In the pathogenesis of central nervous system (CNS) demyelinating disorders, antigen-specific B cells are implicated to act as potent antigen-presenting cells (APC), eliciting waves of inflammatory CNS infiltration. Here, we provide the first evidence that CNS-reactive ... περισσότερα »

CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study.

Alexandros G. SfakianakisστοHead and NeckΠριν από 14 δευτερόλεπτα
*CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study.* Acta Neuropathol. 2016 Mar 28; Authors: Kang JH, Mollenhauer B, Coffey CS, Toledo JB, Weintraub D, Galasko DR, Irwin DJ, Van Deerlin V, Chen-Plotkin AS, Caspell-Garcia C, Waligórska T, Taylor P, Shah N, Pan S, Zero P, Frasier M, Marek K, Kieburtz K, Jennings D, Tanner CM, Simuni T, Singleton A, Toga AW, Chowdhury S, Trojanowski JQ, Shaw LM, Parkinson's Progression Marker Initiative Abstract The development of biomarkers to predict the progressi...περισσότερα »

Cytologic subclassification of atypia of undetermined significance may predict thyroid nodules more likely to be malignant at surgery

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Background The atypia of undetermined significance or follicular lesion of undetermined significance (AUS/FLUS) category in the Bethesda System of reporting thyroid fine-needle aspiration (FNA) includes various cytological findings considered to have a low risk of malignancy. It is still unclear if any particular subset of the cytological findings within this category carries a higher risk for malignancy requiring a more aggressive treatment plan. Methods We reviewed 221 AUS/FLUS FNAs performed between January of 2006 and May of 2012. Histopathological data from surgery was avai... περισσότερα »

Anaplastic Carcinoma Arising in a Mucinous Cystic Neoplasm Masquerading as Pancreatic Pseudocyst

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Mucinous cystic neoplasms (MCN) of the pancreas can vary from benign to premalignant and malignant. Preoperative diagnosis is essential to offer the patient appropriate treatment. Occasionally these cases may harbor anaplastic carcinoma while clinically masquerade as a pseudocyst. Here in, we report an unusual case of a 37-year old female presented with recurrent abdominal pain that was suspected clinically and by imaging studies to have a pseudocyst. EUS-FNA with internal drainage of the cyst was performed. Cytological evaluation of the cyst fluid showed numerous inflammatory cel...περισσότερα »

What Is the Best Way to Measure Surgical Quality?

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Comparing the American College of Surgeons National Surgical Quality Improvement Program versus Traditional Morbidity and Mortality Conferences: [image: image] Background: Morbidity and mortality conferences have played a traditional role in tracking complications. Recently, the American College of Surgeons National Surgical Quality Improvement Program Pediatrics (ACS NSQIP-P) has gained popularity as a risk-adjusted means of addressing quality assurance. The purpose of this article is to report an analysis of the two methodologies used within pediatric plastic surgery to determine ...περισσότερα »

Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen.

Alexandros G. SfakianakisστοHead and NeckΠριν από 16 δευτερόλεπτα
*Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen.* Acta Neuropathol. 2016 Mar 29; Authors: Kinzel S, Lehmann-Horn K, Torke S, Häusler D, Winkler A, Stadelmann C, Payne N, Feldmann L, Saiz A, Reindl M, Lalive PH, Bernard CC, Brück W, Weber MS Abstract In the pathogenesis of central nervous system (CNS) demyelinating disorders, antigen-specific B cells are implicated to act as potent antigen-presenting cells (APC), eliciting waves of inflammatory CNS infiltration. Here, we provide the first evidence that CNS-reactive ... περισσότερα »

CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study.

Alexandros G. SfakianakisστοHead and NeckΠριν από 16 δευτερόλεπτα
*CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study.* Acta Neuropathol. 2016 Mar 28; Authors: Kang JH, Mollenhauer B, Coffey CS, Toledo JB, Weintraub D, Galasko DR, Irwin DJ, Van Deerlin V, Chen-Plotkin AS, Caspell-Garcia C, Waligórska T, Taylor P, Shah N, Pan S, Zero P, Frasier M, Marek K, Kieburtz K, Jennings D, Tanner CM, Simuni T, Singleton A, Toga AW, Chowdhury S, Trojanowski JQ, Shaw LM, Parkinson's Progression Marker Initiative Abstract The development of biomarkers to predict the progressi...περισσότερα »

Correlation of Stomatitis and Cutaneous Toxicity With Clinical Outcome in Patients With Metastatic Renal-Cell Carcinoma Treated With Everolimus.

Alexandros G. SfakianakisστοHead and NeckΠριν από 16 δευτερόλεπτα
*Correlation of Stomatitis and Cutaneous Toxicity With Clinical Outcome in Patients With Metastatic Renal-Cell Carcinoma Treated With Everolimus.* Clin Genitourin Cancer. 2016 Feb 23; Authors: Conteduca V, Santoni M, Medri M, Scarpi E, Burattini L, Lolli C, Rossi L, Savini A, Berardi R, Stanganelli I, Cascinu S, De Giorgi U Abstract BACKGROUND: In clinical practice, discontinuation or dose reduction of everolimus may be induced not only by grade 3 or 4 toxicities but also by prolonged grade 2 toxicities, such as stomatitis and/or cutaneous toxicity, which share some pathogenetic m...περισσότερα »

Candida/Candida biofilms. First description of dual-species Candida albicans/C. rugosa biofilm.

Alexandros G. SfakianakisστοHead and NeckΠριν από 16 δευτερόλεπτα
*Candida/Candida biofilms. First description of dual-species Candida albicans/C. rugosa biofilm.* Fungal Biol. 2016 Apr;120(4):530-7 Authors: Martins CH, Pires RH, Cunha AO, Pereira CA, Singulani Jde L, Abrão F, Moraes Td, Mendes-Giannini MJ Abstract Denture liners have physical properties that favour plaque accumulation and colonization by Candida species, irritating oral tissues and causing denture stomatitis. To isolate and determine the incidence of oral Candida species in dental prostheses, oral swabs were collected from the dental prostheses of 66 patients. All the strains ...περισσότερα »

High-dose-rate brachytherapy using molds for lip and oral cavity tumors.

Alexandros G. SfakianakisστοHead and NeckΠριν από 16 δευτερόλεπτα
Related Articles *High-dose-rate brachytherapy using molds for lip and oral cavity tumors.* Radiat Oncol. 2015;10:81 Authors: Unetsubo T, Matsuzaki H, Takemoto M, Katsui K, Hara M, Katayama N, Waki T, Kanazawa S, Asaumi J Abstract BACKGROUND: High-dose-rate (HDR) brachytherapy using the mold technique is a less invasive treatment for early lip and oral cavity cancer. However, limited reports exist regarding the feasibility of this method. In this retrospective study, we evaluated the outcome of this therapy and investigated its feasibility for lip and oral cavity tumors. METHODS:...περισσότερα »

Associations of rs4810485 and rs1883832 polymorphisms of CD40 gene with susceptibility and clinical findings of Behçet's disease.

Alexandros G. SfakianakisστοHead and NeckΠριν από 16 δευτερόλεπτα
Related Articles *Associations of rs4810485 and rs1883832 polymorphisms of CD40 gene with susceptibility and clinical findings of Behçet's disease.* Rheumatol Int. 2015 May;35(5):837-43 Authors: İnal EE, Rüstemoğlu A, İnanır A, Ekinci D, Gül Ü, Yiğit S, Ateş Ö Abstract There are evidences that besides geographic tendency, interactions between genetic and environmental factors play an essential role in the pathogenesis of Behçet's disease (BD). In this study, we have evaluated the associations between rs4810485 and rs1883832 single nucleotide polymorphism (SNP)s of CD40 gene with ...περισσότερα »

Nitroglycerin Ointment on Flap Necrosis in Immediate Reconstruction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Effects of Nitroglycerin Ointment on Mastectomy Flap Necrosis in Immediate Breast Reconstruction: A Randomized Controlled Trial: Sir: The following comments refer to “Effects of Nitroglycerin Ointment on Mastectomy Flap Necrosis in Immediate Breast Reconstruction: A Randomized Controlled Trial” (*Plast Reconstr Surg*. 2015;135:1530–1539).1 I have read the article with great interest and am planning to apply the nitroglycerin ointment to my patients. Before using it in my cases, I really want to get answers to the followings questions. As the authors insisted, this is the first ran... περισσότερα »

Low Rates of Blood Transfusion in Elective Resections of Neurofibromas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
in a Cohort Study: Neurofibroma Length as a Predictor of Transfusion Requirement: [image: image] Background: Neurofibromas in neurofibromatosis type 1 induce aesthetic and functional morbidity. Perioperative bleeding has been reported as an obstacle to neurofibroma resections. The authors studied the requirement for blood transfusion during surgical treatment of neurofibromatosis type 1. Methods: Six hundred twenty-two procedures performed on 390 neurofibromatosis type 1 patients at the national referral center from 1995 to 2011 were analyzed in two chronologic sets of patients: s... περισσότερα »

Principles for Management of Orbital Fractures in the Pediatric Population

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
A Cohort Study of 150 Patients: Abstract Background: Pediatric orbital fractures represent a challenging and sometimes controversial clinical problem. Patients may present with clear indications for surgery, but most require balancing benefits against intraoperative and late complications. The authors assessed these fractures at a state-designated ophthalmology referral center to develop criteria for surgery. Methods: Institutional review board approval was obtained to retrospectively analyze pediatric trauma registry patients with orbital fracture diagnoses at the Wilmer Eye In... περισσότερα »

Surgical Treatment of Facial Infantile Hemangiomas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
An Analysis Based on Tumor Characteristics and Outcomes: Background: Surgical treatment of infantile hemangiomas may interfere with patient appearance. The use of an algorithm is essential to select candidates. The objective of this study was to evaluate outcomes of surgical treatment based on tumor characteristics. Methods: Seventy-four patients were treated surgically between 1997 and 2010. Demographics, tumor characteristics, surgical approach, and outcomes were evaluated. Results: The female-to-male ratio was 5.7:1. Mean age and follow-up were 24 years and 33 months, respective...περισσότερα »

Ibuprofen May Not Increase Bleeding Risk in Plastic Surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
A Systematic Review and Meta-Analysis: Background: Nonsteroidal antiinflammatory drugs such as ibuprofen are common medications with multiple useful effects, including pain relief and reduction of inflammation. However, surgeons commonly withhold all nonsteroidal antiinflammatory drugs perioperatively because of bleeding concerns. However, not all nonsteroidal antiinflammatory drugs irreversibly block platelet function. The authors hypothesized that the use of ibuprofen would have no effect on postoperative bleeding in plastic surgery patients. Methods: A literature review was perfo... περισσότερα »

Carbon Ion Implantation: A Good Method to Enhance the Biocompatibility of Silicone Rubber

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Carbon Ion Implantation: A Good Method to Enhance the Biocompatibility of Silicone Rubber: [image: image] Background: Silicone rubber and silicone rubber–based materials have been used as medical tissue implants in the field of plastic surgery for many years, but there are still some reports of adverse reactions to long-term implants. Earlier studies have shown that ion implantation could enhance the biocompatibility of biomaterials. However, whether ion implantation has a good effect on silicone rubber is unknown. Methods: Three types of carbon ion silicone rubber were obtained by...περισσότερα »

Heat Shock Protein 90 Inhibitor Decreases Collagen Synthesis of Keloid Fibroblasts and Attenuates the Extracellular Matrix on the Keloid Spheroid Model

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Heat Shock Protein 90 Inhibitor Decreases Collagen Synthesis of Keloid Fibroblasts and Attenuates the Extracellular Matrix on the Keloid Spheroid Model: Sir: We have read the article by Lee et al. with interest.1 Because transforming growth factor (TGF)-β/Smad signaling plays a central role in keloid pathogenesis, modulation of TGF-β synthesis or activity represents a potential approach for treating hypertrophic scar and keloids. Wrighton et al. found that inhibition of heat-shock protein 90 function increases TGF-β receptor ubiquitination and degradation in a Smurf2 ubiquitin E... περισσότερα »

Angiogenesis inhibitor; +25 new citations

Alexandros G. SfakianakisστοHead and NeckΠριν από 21 δευτερόλεπτα
25 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Angiogenesis inhibitor* These pubmed results were generated on 2016/03/30 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1olHpOS via IFTTT

Improvement of Fat Graft Survival with Autologous Bone Marrow Aspirate and Bone Marrow Concentrate: A One-Step Method

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Improvement of Fat Graft Survival with Autologous Bone Marrow Aspirate and Bone Marrow Concentrate: A One-Step Method: [image: image]Background: Stem cells have proven to be beneficial to fat graft survival, but a one-step method of cell-assisted lipotransfer is still missing. In the present work, the authors improved the fat graft survival using bone marrow aspirate and bone marrow concentrate, to ensure that both liposuction and cell-assisted lipotransfer were included in the same procedure. Methods: Bone marrow aspirate was collected from the iliac crest of the rabbits. Bone m... περισσότερα »

Sporadic Multiple Symmetric Lipomatosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Transcription Profile in Sporadic Multiple Symmetric Lipomatosis Reveals Differential Expression at the Level of Adipose Tissue–Derived Stem Cells: [image: image]Background: The cause of the rare fat distribution disorder multiple symmetric lipomatosis is unknown. Independent reports suggest a higher proliferative activity, hormone resistance, and involvement of mitochondrial function in the disease. Methods: The authors performed morphologic comparison of affected and unaffected tissues in five unrelated patients and generated adipose-derived stem cell cultures from the tissue samp... περισσότερα »

Adipose Tissue and Extracellular Matrix Development by Injectable Decellularized Adipose Matrix Loaded with Basic Fibroblast Growth Factor

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Adipose Tissue and Extracellular Matrix Development by Injectable Decellularized Adipose Matrix Loaded with Basic Fibroblast Growth Factor: Background: There is a significant need for soft-tissue replacements in the field of reconstructive surgery. Decellularized adipose tissues were heparin crosslinked and loaded with basic fibroblast growth factor (bFGF). This injectable system was evaluated for its adipogenic and angiogenic capabilities for in vivo adipose tissue regeneration. Methods: Decellularized adipose tissues were harvested from the inguinal fat pads of C57BL/6J mice, minc... περισσότερα »

Robotically Assisted Microsurgery versus Manual Microsurgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
in Challenging Situations: Background: Microsurgery can be challenging secondary to orientation of the vessels, accessibility, or depth of the wound. Robotically assisted microsurgery reduces tremors and improves visualization and may improve the quality of anastomosis compared with traditional microsurgery. The purpose of this study was to compare robotically assisted microsurgery to traditional microsurgery in technically challenging situations with respect to time of anastomosis, quality of anastomosis, and Objective Structured Assessment of Technical Skills. Methods: Two inves...περισσότερα »

Secondary Neck Lift and the Importance of Midline Platysmaplasty

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Review of 101 Cases: [image: image] Background: The authors believe that open access to the submental region, platysmaplasty, and wide skin undermining provide the most long-lasting results in neck rejuvenation, and sought to evaluate this hypothesis by reviewing their neck-lift patients. Methods: The authors performed a retrospective chart review of their experience with neck-lift procedures and patients who underwent a secondary procedure. Patient age, sex, initial technique, visible neck deformities, and reasons for revision were assessed. Photographs were used to assess the fe...περισσότερα »

Ex vivo Renal Artery Repair with Kidney Autotransplantation for Renal Artery Branch Aneurysms: Long-term Results of Sixty-seven Procedures

Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 24 δευτερόλεπτα
Publication date: Available online 29 March 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): A. Duprey, B. Chavent, V. Meyer-Bisch, T. Varin, J.-N. Albertini, J.-P. Favre, X. Barral, J.-B. Ricco Objective/BackgroundTo evaluate the long-term outcome of renal revascularization by ex vivo renal artery reconstruction and autotransplantation for renal artery branch aneurysms (RABAs).MethodsBetween 1991 and 2015, 67 ex vivo renal artery reconstructions with kidney autotransplantation were performed in 55 adults (mean age 47 years) and 10 children to repair 87... περισσότερα »

Robot assisted Aortic and Non-aortic Vascular Operations

Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 24 δευτερόλεπτα
Publication date: Available online 29 March 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): P. Štádler, L. Dvořáček, P. Vitásek, P. Matouš BackgroundThe aim of this study was to evaluate the clinical experience with 310 robot assisted vascular procedures. The da Vinci system has been used by a variety of disciplines for laparoscopic procedures but the use of robots in vascular surgery is still relatively uncommon.MethodsFrom November 2005 to May 2014, 310 robot assisted vascular operations were performed. Two hundred and twenty four patients were prospe...περισσότερα »

Three Formulations of Botulinum Toxin Type A for Facial Rhytides

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
A Systematic Review with Meta-Analyses: [image: image] Background: Three formulations of botulinum toxin are available for facial rhytides. It is unclear which formulation offers the greatest balance of benefits and harms. The objective of this study was to conduct a systematic review with meta-analyses to compare formulations of botulinum toxin for reduction of facial rhytides at the glabella. Methods: The authors’ protocol was registered with the International Prospective Register of Systematic Reviews (CRD4201200377). A systematic literature search was performed identifying doub... περισσότερα »

Anatomical Considerations to Prevent Facial Nerve Injury

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Reply: Sir: We congratulate Dr. Visconti and Dr. Salgarello for their letter, as it nicely complements our article entitled “Anatomical Considerations to Prevent Facial Nerve Injury.”1 Their comments and figures help further clarify our attempt to improve understanding of facial nerve anatomy and the planes of dissection that are safe and help avoid injury. The complexity of facial nerve branches and their variable course can be appreciated in the elegant dissection performed by Dr. Visconti and Dr. Salgarello. Their anatomical figures further highlight the importance of understan... περισσότερα »

Tissue Oximetry Monitoring

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Does Increased Experience with Tissue Oximetry Monitoring in Microsurgical Breast Reconstruction Lead to Decreased Flap Loss? The Learning Effect: [image: image]Background: Early studies have shown that near-infrared monitoring with tissue oximetry shows promise in providing earlier detection of free flap vascular compromise. However, large-scale clinical evaluation of this technology on flap outcome has not previously been established. This study examines the effect of tissue oximetry on flap reexploration rates and salvage over a 10-year period. The learning curve for this new t... περισσότερα »

Issue Information

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 25 δευτερόλεπτα
*Cover of this issue.* *In vivo* luciferase assay to evaluate peritoneal dissemination in mice. See also Takahashi, R., *et al*. (pages 341–346 of this issue). from Cancer via ola Kala on Inoreader http://ift.tt/1LZDgvo via IFTTT

Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 25 δευτερόλεπτα
[image: cover.gif?v=1&s=baeb31fd8e876f883e44d031] The Japan Diabetes Society/Japanese Cancer Association Joint Committee on Diabetes and Cancer published its first report in July 2013 on the epidemiological assessment of the associations of diabetes with cancer risk/prognosis, the common risk factors for diabetes and cancer, and cancer risk associated with diabetes treatment. The Joint Committee continued its work to assess the role of glycemic control in the development of cancer in patients with diabetes. This review shows that high-quality evidence examining the association bet... περισσότερα »

Gene Aberrations for Precision Medicine against Lung Adenocarcinoma

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 25 δευτερόλεπτα
[image: cover.gif?v=1&s=baeb31fd8e876f883e44d031] Abstract Lung adenocarcinoma (LADC), the most frequent histological type of lung cancer, is often triggered by an aberration in a driver oncogene in tumor cells. Examples of such aberrations are *EGFR* mutation and *ALK* fusion. LADC harboring such mutations can be treated with anti-cancer drugs that target the aberrant gene products. Additional oncogene aberrations, including *RET*, *ROS1*, and *NRG1* fusions, skipping of exon 14 of *MET*, and mutations in *BRAF*, *HER2*, *NF1*, and *MEK1*, were recently added to the list of such... περισσότερα »

MYC translocation and/or BCL2 protein expression are associated with poor prognosis in diffuse large B-cell lymphoma

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 25 δευτερόλεπτα
Abstract Genomic alterations and protein expression levels have been established as prognostic factors for survival in patients with diffuse large B-cell lymphoma (DLBCL). In particular, double-hit DLBCL (DHL), which exhibits translocations in *MYC* and *BCL2* and/or *BCL6*, is known to be associated with a poor prognosis. However, the clinical significance of gene alterations and protein expression levels for MYC, BCL2, and BCL6 are unclear. In this study, we analyzed 61 adult patients diagnosed with DLBCL without DHL, who were treated with rituximab, cyclophosphamide, doxorubici...περισσότερα »

Remote Sensing, Vol. 8, Pages 295: Performance Evaluation of Cluster Validity Indices (CVIs) on Multi/Hyperspectral Remote Sensing Datasets

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
The number of clusters (i.e., the number of classes) for unsupervised classification has been recognized as an important part of remote sensing image clustering analysis. The number of classes is usually determined by cluster validity indices (CVIs). Although many CVIs have been proposed, few studies have compared and evaluated their effectiveness on remote sensing datasets. In this paper, the performance of 16 representative and commonly-used CVIs was comprehensively tested by applying the fuzzy c-means (FCM) algorithm to cluster nine types of remote sensing datasets, including m...περισσότερα »

Minerals, Vol. 6, Pages 27: Minerals in the Ash and Slag from Oxygen-Enriched Underground Coal Gasification

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Underground coal gasification (UCG) is a promising option for the recovery of low-rank and inaccessible coal resources. Detailed mineralogical information is essential to understand underground reaction conditions far from the surface and optimize the operation parameters during the UCG process. It is also significant in identifying the environmental effects of UCG residue. In this paper, with regard to the underground gasification of lignite, UCG slag was prepared through simulation tests of oxygen-enriched gasification under different atmospheric conditions, and the minerals were... περισσότερα »

Remote Sensing, Vol. 8, Pages 292: An Integrated Field and Remote Sensing Method for Mapping Seagrass Species, Cover, and Biomass in Southern Thailand

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Accurate and up-to-date maps of seagrass biodiversity are important for marine resource management but it is very challenging to test the accuracy of remote sensing techniques for mapping seagrass in coastal waters with variable water turbidity. In this study, Worldview-2 (WV-2) imagery was combined with field sampling to demonstrate the capability of mapping species type, percentage cover, and above-ground biomass of seagrasses in monsoonal southern Thailand. A high accuracy positioning technique, involving the Real Time Kinematic (RTK) Global Navigation Satellite System (GNSS), ...περισσότερα »

Designing Digital Solutions for Preserving Penan Sign Language: A Reflective Study

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Oroo' is a language of nomadic Penans in the rainforests of Borneo and the only way of asynchronous communication between nomadic groups in the forest journey. Like many other indigenous languages, the Oroo' language is also facing imminent extinction. In this paper, we present the research process and reflections of a multidisciplinary community-based research project on digitalizing and preserving the Oroo' sign language. As a methodology for project activities, we are employing Participatory Action Research in Software Development Methodology Augmentation (PRISMA). Preliminary r...περισσότερα »

Agriculture, Vol. 6, Pages 13: A Comparative Analysis of Productivity among Organic and Non-Organic farms in the West Mamprusi District of Ghana

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
The study was conducted in organic and conventional crop farms in the West Mamprusi District of the Northern Region of Ghana. The key issue the study sought to determine was whether there are productivity differences among organic and conventional crop farms and what factors account for these differences. The results indeed revealed that there are productivity differences among organic and conventional crop farms. However, both had negative total factor productivity growth, largely accounted for by a negative technical change over the period considered. The technical efficiency ch...περισσότερα »

IJERPH, Vol. 13, Pages 389: Childhood Reports of Food Neglect and Impulse Control Problems and Violence in Adulthood

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Food insecurity and hunger during childhood are associated with an array of developmental problems in multiple domains, including impulse control problems and violence. Unfortunately, extant research is based primarily on small convenience samples and an epidemiological assessment of the hunger-violence link is lacking. The current study employed data from Wave 1 (2001–2002) and Wave 2 (2004–2005) of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). The NESARC is a nationally representative sample of non-institutionalized U.S. residents aged 18 years an...περισσότερα »

Water, Vol. 8, Pages 124: Decline in Performance of Biochemical Reactors for Sulphate Removal from Mine-Influenced Water is Accompanied by Changes in Organic Matter Characteristics and Microbial Population Composition

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Successful long-term bioremediation of mining-influenced water using complex organic matter and naturally-occurring microorganisms in sub-surface flow constructed wetlands requires a balance between easily and more slowly degrading material. This can be achieved by combining different types of organic materials. To provide guidance on what mixture combinations to use, information is needed on how the ratio of labile to recalcitrant components affects the degradation rate and the types of microbial populations supported. To investigate this, different ratios of wood and hay were us...περισσότερα »

IJERPH, Vol. 13, Pages 387: Determination and Distribution of Polycyclic Aromatic Hydrocarbons in Rivers, Sediments and Wastewater Effluents in Vhembe District, South Africa

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Polycyclic aromatic hydrocarbons are very toxic and persistent environmental contaminants. This study was undertaken to assess the concentrations and possible sources of 16 PAHs (Polycyclic aromatic hydrocarbons) classified by the United State Environmental Protection Agency as priority pollutants in water and sediments of the Mvudi and Nzhelele Rivers. Effluents from Thohoyandou wastewater treatment plant and Siloam waste stabilization ponds were also investigated. Diagnostic ratios were used to evaluate the possible sources of PAHs. PAHs in the water samples were extracted using...περισσότερα »

IJERPH, Vol. 13, Pages 388: Pyrethroid Pesticide Metabolite in Urine and Microelements in Hair of Children Affected by Autism Spectrum Disorders: A Preliminary Investigation

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
The number of children affected by Autism Spectrum Disorders (ASD) is dramatically increasing as well as the studies aimed at understanding the risk factors associated with the development of ASD. Since the etiology of ASD is partly genetic and partly environmental, factors (i.e., heavy metals, pesticides) as well as lifestyle seem to have a key role in the development of the disease. ASD and Control (CTR) children, aged 5–12 years, were compared. Gas chromatography coupled with trap mass detector was used to measure the level of 3-PBA, the main pyrethroid metabolite in urine in a...περισσότερα »

IJERPH, Vol. 13, Pages 386: Children’s Exposure to Radon in Nursery and Primary Schools

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
The literature proves an evident association between indoor radon exposure and lung cancer, even at low doses. This study brings a new approach to the study of children's exposure to radon by aiming to evaluate exposure to indoor radon concentrations in nursery and primary schools from two districts in Portugal (Porto and Bragança), considering different influencing factors (occupation patterns, classroom floor level, year of the buildings' construction and soil composition of the building site), as well as the comparison with IAQ standard values for health protection. Fifteen nur... περισσότερα »

Energies, Vol. 9, Pages 251: Optimization of the Heating System Use in Aged Public Buildings via Model Predictive Control

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
This work presents the implementation of a Model Predictive Control (MPC) scheme used to study the improvement of the thermal quality in aged residential buildings without any rehabilitation. The controller manages the heating system of an experimentally characterized model of a residential dwelling in a social block built during the decade of the 1960s located in the neighborhood of Otxarkoaga (Bilbao, Spain), so as to obtain an optimal energy efficiency performance. Due to the characteristics of the construction in those days, this kind of buildings suffer problems related to th... περισσότερα »

IJERPH, Vol. 13, Pages 385: Modeling Associations between Principals’ Reported Indoor Environmental Quality and Students’ Self-Reported Respiratory Health Outcomes Using GLMM and ZIP Models

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Background: The aim of this paper was to examine associations between school building characteristics, indoor environmental quality (IEQ), and health responses using questionnaire data from both school principals and students. Methods: From 334 randomly sampled schools, 4248 sixth grade students from 297 schools participated in a questionnaire. From these schools, 134 principals returned questionnaires concerning 51 IEQ related questions of their school. Generalized linear mixed models (GLMM) were used to study the associations between IEQ indicators and existence of self-reported... περισσότερα »

Water, Vol. 8, Pages 122: Bivariate Drought Analysis Using Streamflow Reconstruction with Tree Ring Indices in the Sacramento Basin, California, USA

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Long-term streamflow data are vital for analysis of hydrological droughts. Using an artificial neural network (ANN) model and nine tree-ring indices, this study reconstructed the annual streamflow of the Sacramento River for the period from 1560 to 1871. Using the reconstructed streamflow data, the copula method was used for bivariate drought analysis, deriving a hydrological drought return period plot for the Sacramento River basin. Results showed strong correlation among drought characteristics, and the drought with a 20-year return period (17.2 million acre-feet (MAF) per year)... περισσότερα »

Viruses, Vol. 8, Pages 93: Enterovirus Control of Translation and RNA Granule Stress Responses

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Enteroviruses such as poliovirus (PV) and coxsackievirus B3 (CVB3) have evolved several parallel strategies to regulate cellular gene expression and stress responses to ensure efficient expression of the viral genome. Enteroviruses utilize their encoded proteinases to take over the cellular translation apparatus and direct ribosomes to viral mRNAs. In addition, viral proteinases are used to control and repress the two main types of cytoplasmic RNA granules, stress granules (SGs) and processing bodies (P-bodies, PBs), which are stress-responsive dynamic structures involved in repre... περισσότερα »

IJERPH, Vol. 13, Pages 384: Mapping Copper and Lead Concentrations at Abandoned Mine Areas Using Element Analysis Data from ICP–AES and Portable XRF Instruments: A Comparative Study

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Understanding spatial variation of potentially toxic trace elements (PTEs) in soil is necessary to identify the proper measures for preventing soil contamination at both operating and abandoned mining areas. Many studies have been conducted worldwide to explore the spatial variation of PTEs and to create soil contamination maps using geostatistical methods. However, they generally depend only on inductively coupled plasma atomic emission spectrometry (ICP–AES) analysis data, therefore such studies are limited by insufficient input data owing to the disadvantages of ICP–AES analysis... περισσότερα »

Entropy, Vol. 18, Pages 115: A Comparison of Classification Methods for Telediagnosis of Parkinson’s Disease

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Parkinson's disease (PD) is a progressive and chronic nervous system disease that impairs the ability of speech, gait, and complex muscle-and-nerve actions. Early diagnosis of PD is quite important for alleviating the symptoms. Cost effective and convenient telemedicine technology helps to distinguish the patients with PD from healthy people using variations of dysphonia, gait or motor skills. In this study, a novel telemedicine technology was developed to detect PD remotely using dysphonia features. Feature transformation and several machine learning (ML) methods with 2-, 5- and ... περισσότερα »

Sustainability, Vol. 8, Pages 320: Integrating Urban Heat Assessment in Urban Plans

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
The world is increasingly concerned with sustainability issues. Climate change is not the least of these concerns. The complexity of these issues is such that data and information management form an important means of making the right decisions. Nowadays, however, the sheer quantity of data is overwhelming; large quantities of data demand means of representation that are comprehensible and effective. The above dilemma poses questions as to how one incorporates unknown climatologic parameters, such as urban heat, in future urban planning processes, and how one ensures the proposals ... περισσότερα »

Remote Sensing, Vol. 8, Pages 293: Error Analysis of Satellite Precipitation-Driven Modeling of Flood Events in Complex Alpine Terrain

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
The error in satellite precipitation-driven complex terrain flood simulations is characterized in this study for eight different global satellite products and 128 flood events over the Eastern Italian Alps. The flood events are grouped according to two flood types: rain floods and flash floods. The satellite precipitation products and runoff simulations are evaluated based on systematic and random error metrics applied on the matched event pairs and basin-scale event properties (i.e., rainfall and runoff cumulative depth and time series shape). Overall, error characteristics exhib... περισσότερα »

Remote Sensing, Vol. 8, Pages 294: Multiyear Arctic Ice Classification Using ASCAT and SSMIS

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
The concentration, type, and extent of sea ice in the Arctic can be estimated based on measurements from satellite active microwave sensors, passive microwave sensors, or both. Here, data from the Advanced Scatterometer (ASCAT) and the Special Sensor Microwave Imager/Sounder (SSMIS) are employed to broadly classify Arctic sea ice type as first-year (FY) or multiyear (MY). Combining data from both active and passive sensors can improve the performance of MY and FY ice classification. The classification method uses C-band σ0 measurements from ASCAT and 37 GHz brightness temperature ... περισσότερα »

Sustainability, Vol. 8, Pages 304: Are Australian and United States Farmers Using Soil Information for Soil Health Management?

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Soil health is an essential requirement of a sustainable, functioning agroecosystem. Tracking soil health to determine sustainability at the local level largely falls to farmers, even though they often lack access to critical information. We examine farmers' participation in gathering soil information at the farm and paddock scale over the last two decades in Australia and the United States, by reviewing national-level reporting of farmer use of soil testing and farm planning as well as qualitative research on farmer perspectives. The level of participation in soil testing and far... περισσότερα »

Paravertebral Block versus General Anesthesia Alone

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
A Prospective, Randomized, Controlled Trial of Paravertebral Block versus General Anesthesia Alone for Prosthetic Breast Reconstruction: [image: image]Background: Paravertebral blocks have gained popularity because of ease of implementation and a shift toward ambulatory breast surgery procedures. Previous retrospective studies have reported potential benefits of paravertebral blocks, including decreased narcotic and antiemetic use. Methods: The authors conducted a prospective controlled trial of patients undergoing breast reconstruction over a 3-year period. The patients were ran... περισσότερα »

Current Concepts Related to Hypertrophic Scarring in Burn Injuries

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Current Concepts Related to Hypertrophic Scarring in Burn Injuries: [image: cover.gif?v=1&s=00eca2b4f3bb0b83a2b9cbac] Abstract Scarring following burn injury and its accompanying aesthetic and functional sequelae still pose major challenges. Hypertrophic scarring (HTS) can greatly impact patients' quality of life related to appearance, pain, pruritus and even loss of function of the injured body region. The identification of molecular events occurring in the evolution of the burn scar has increased our knowledge; however, this information has not yet translated into effective tr... περισσότερα »

A comparative study using WHO and binary oral epithelial dysplasia grading systems in actinic cheilitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
A comparative study using WHO and binary oral epithelial dysplasia grading systems in actinic cheilitis: [image: cover.gif?v=1&s=27703ad39525d3c4795e45b7] Abstract Objective To evaluate comparatively the influence of histopathological features on epithelial dysplasia (ED) and the effectiveness in usage of WHO and binary grading systems in actinic cheilitis (AC). Material and methods Cytological and architectural alterations established by WHO for ED were evaluated in 107 cases of AC. ED was graded using WHO and binary systems. The comparisons were performed using Kappa, chi-squar... περισσότερα »

In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol®

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
In Situ, Autologous Therapeutic Vaccination Against Solid Cancers With Intratumoral Hiltonol®: *Conditions*: Melanoma; Head and Neck Cancer; Sarcoma; Non-Melanoma Skin Cancers *Intervention*: Biological: Hiltonol *Sponsors*: Oncovir, Inc.; National Institutes of Health (NIH); Icahn School of Medicine at Mount Sinai; Bay Hematology Oncology; Medical University of South Carolina; Emory University; University of Pittsburgh; National Cancer Institute (NCI) ArmsAssigned Interventions Experimental: Hiltonol Poly-ICLC This is an adaptive design protocol. A total... περισσότερα »

Irreversible Electroporation(IRE) For Unresectable Laryngeal Neoplasms

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
Irreversible Electroporation(IRE) For Unresectable Laryngeal Neoplasms: *Condition*: Laryngeal Neoplasms *Interventions*: Procedure: Irreversible electroporation (IRE); Device: NanoKnife *Sponsor*: Fuda Cancer Hospital, Guangzhou ArmsAssigned Interventions Experimental: Group A irreversible electroporation for Unresectable Laryngeal Neoplasms Procedure: Irreversible electroporation (IRE) Irreversible Electroportion For Unresectable Rectal Neoplasms guide with ultrasound or/and CT. Other Name: NanoKnife Device: NanoKnife Detailed Description:By enrolling patients with unrese...περισσότερα »

The OSA-18 predictive of obstructive sleep apnea: Comparison to polysomnography

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
In reference to: Is the OSA-18 predictive of obstructive sleep apnea: Comparison to polysomnography: [image: cover.gif?v=1&s=634ce17de2958347d854769c]

Associations of rs4810485 and rs1883832 polymorphisms of CD40 gene with susceptibility and clinical findings of Behçet's disease.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
Associations of rs4810485 and rs1883832 polymorphisms of CD40 gene with susceptibility and clinical findings of Behçet's disease.: Authors: İnal EE, Rüstemoğlu A, İnanır A, Ekinci D, Gül Ü, Yiğit S, Ateş Ö Abstract There are evidences that besides geographic tendency, interactions between genetic and environmental factors play an essential role in the pathogenesis of Behçet's disease (BD). In this study, we have evaluated the associations between rs4810485 and rs1883832 single nucleotide polymorphism (SNP)s of CD40 gene with the susceptibility and clinical findings of BD. Two hundr... περισσότερα »

High-dose-rate brachytherapy using molds for lip and oral cavity tumors.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
High-dose-rate brachytherapy using molds for lip and oral cavity tumors.: Authors: Unetsubo T, Matsuzaki H, Takemoto M, Katsui K, Hara M, Katayama N, Waki T, Kanazawa S, Asaumi J Abstract BACKGROUND: High-dose-rate (HDR) brachytherapy using the mold technique is a less invasive treatment for early lip and oral cavity cancer. However, limited reports exist regarding the feasibility of this method. In this retrospective study, we evaluated the outcome of this therapy and investigated its feasibility for lip and oral cavity tumors. METHODS: Between May 2002 and December 2010, 17 patie...περισσότερα »

Candida/Candida biofilms. First description of dual-species Candida albicans/C. rugosa biofilm.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
Candida/Candida biofilms. First description of dual-species Candida albicans/C. rugosa biofilm Fungal Biol. 2016 Apr;120(4):530-7 Authors: Martins CH, Pires RH, Cunha AO, Pereira CA, Singulani Jde L, Abrão F, Moraes Td, Mendes-Giannini MJ Abstract Denture liners have physical properties that favour plaque accumulation and colonization by Candida species, irritating oral tissues and causing denture stomatitis. To isolate and determine the incidence of oral Candida species in dental prostheses, oral swabs were collected from the dental prostheses of 66 patients. All the strains were...περισσότερα »

Correlation of Stomatitis and Cutaneous Toxicity With Clinical Outcome in Patients With Metastatic Renal-Cell Carcinoma Treated With Everolimus.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
Correlation of Stomatitis and Cutaneous Toxicity With Clinical Outcome in Patients With Metastatic Renal-Cell Carcinoma Treated With Everolimus.: Authors: Conteduca V, Santoni M, Medri M, Scarpi E, Burattini L, Lolli C, Rossi L, Savini A, Berardi R, Stanganelli I, Cascinu S, De Giorgi U Abstract BACKGROUND: In clinical practice, discontinuation or dose reduction of everolimus may be induced not only by grade 3 or 4 toxicities but also by prolonged grade 2 toxicities, such as stomatitis and/or cutaneous toxicity, which share some pathogenetic mechanisms. We assessed the correlation ...περισσότερα »

Oesophageal narrowing on barium oesophagram is more common in adult patients with eosinophilic oesophagitis than PPI-responsive oesophageal eosinophilia

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
Oesophageal narrowing on barium oesophagram is more common in adult patients with eosinophilic oesophagitis than PPI-responsive oesophageal eosinophilia: Summary Background To date there have been no clear features that aid in differentiating patients with eosinophilic oesophagitis (EoE) from PPI-responsive oesophageal eosinophilia (PPI-REE). However, barium swallow roentgenography is a more sensitive and specific measure to detect subtle fibrostenotic remodeling changes present in EoE. We aim to characterise any clinical, endoscopic, histiological or barium roentgenographic differ... περισσότερα »

3D soft tissue landmark identification using three-dimensional stereophotogrammetry

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Reproducibility and reliability of three-dimensional soft tissue landmark identification using three-dimensional stereophotogrammetry by Asli Baysal via Edward H. Angle Society of Orthodontist: The Angle Orthodontist: Table of Contents The Angle Orthodontist, Ahead of Print. *Asli Baysal a; Ahmet Oguz Sahan b; Mehmet Ali Ozturk c; Tancan Uysal d* a Associate Professor, Department of Orthodontics, Faculty of Dentistry, Izmir Katip Celebi University, Izmir, Turkey. b Research Assistant, Department of Orthodontics, Faculty of Dentistry, Izmir Katip Celebi University, Izmir, Turkey. c Ass... περισσότερα »

A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.

Alexandros G. SfakianakisστοHead and NeckΠριν από 32 δευτερόλεπτα
*A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.* Sensors (Basel). 2016;16(4) Authors: Martín-Ruiz ML, Máximo-Bocanegra N, Luna-Oliva L Abstract The importance of an early rehabilitation process in children with cerebral palsy (CP) is widely recognized. On the one hand, new and useful treatment tools such as rehabilitation systems based on interactive technologies have appeared for rehabilitation of gross motor movements. On the other hand, from the therapeutic point of view, performing rehabilitation exercises with the f... περισσότερα »

[Retrospective analysis to evaluate efficacy and safety of stereotactic radiosurgery in Cushing's disease: 24 cases and a review].

Alexandros G. SfakianakisστοHead and NeckΠριν από 32 δευτερόλεπτα
*[Retrospective analysis to evaluate efficacy and safety of stereotactic radiosurgery in Cushing's disease: 24 cases and a review].* Neurocirugia (Astur). 2016 Mar 22; Authors: Roldán Serrano MA, Horcajadas Almansa A, Torres Vela E, Sánchez Corral C, Moliz Molina N Abstract BACKGROUND: In the past few years, stereotactic radiosurgery (SRS) has been suggested as a good alternative, second line therapy for the management of patients with ACTH-secreting pituitary adenomas. A retrospective study has been conducted in order to evaluate the efficacy and safety of this treatment in thes...περισσότερα »

Papular acantholytic dyskeratosis of the vulva associated with familial Hailey–Hailey disease

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 36 δευτερόλεπτα
Summary Papular acantholytic dyskeratosis (PAD) of the vulva is a rare, chronic disorder first described in 1984. It presents in young women as white to skin-coloured smooth papules over the vulva, which are persistent but asymptomatic. Histologically, there is hyperkeratosis and focal parakeratosis with acantholytic and dyskeratotic cells forming corps ronds and grains, placing PAD within Ackerman's spectrum of focal acantholytic dyskeratoses with Hailey–Hailey disease (HHD) and Darier disease. There have been 17 previous reports of PAD of the vulva, to our knowledge. Only one de... περισσότερα »

Efficacy and safety of ustekinumab in a group of 22 elderly patients with psoriasis over a 2-year period

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 36 δευτερόλεπτα
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1LZEU05 via IFTTT

Monocyte Subsets and Related Chemokines in Carotid Artery Stenosis and Ischemic Stroke.

Alexandros G. SfakianakisστοHead and NeckΠριν από 36 δευτερόλεπτα
*Monocyte Subsets and Related Chemokines in Carotid Artery Stenosis and Ischemic Stroke.* Int J Mol Sci. 2016;17(4) Authors: Grosse GM, Schulz-Schaeffer WJ, Teebken OE, Schuppner R, Dirks M, Worthmann H, Lichtinghagen R, Maye G, Limbourg FP, Weissenborn K Abstract Carotid stenosis (CS) is an important cause of ischemic stroke. However, reliable markers for the purpose of identification of high-risk, so-called vulnerable carotid plaques, are still lacking. Monocyte subsets are crucial players in atherosclerosis and might also contribute to plaque rupture. In this study we, therefo...περισσότερα »

Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen.

Alexandros G. SfakianakisστοHead and NeckΠριν από 36 δευτερόλεπτα
*Myelin-reactive antibodies initiate T cell-mediated CNS autoimmune disease by opsonization of endogenous antigen.* Acta Neuropathol. 2016 Mar 29; Authors: Kinzel S, Lehmann-Horn K, Torke S, Häusler D, Winkler A, Stadelmann C, Payne N, Feldmann L, Saiz A, Reindl M, Lalive PH, Bernard CC, Brück W, Weber MS Abstract In the pathogenesis of central nervous system (CNS) demyelinating disorders, antigen-specific B cells are implicated to act as potent antigen-presenting cells (APC), eliciting waves of inflammatory CNS infiltration. Here, we provide the first evidence that CNS-reactive ... περισσότερα »

CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study.

Alexandros G. SfakianakisστοHead and NeckΠριν από 36 δευτερόλεπτα
*CSF biomarkers associated with disease heterogeneity in early Parkinson's disease: the Parkinson's Progression Markers Initiative study.* Acta Neuropathol. 2016 Mar 28; Authors: Kang JH, Mollenhauer B, Coffey CS, Toledo JB, Weintraub D, Galasko DR, Irwin DJ, Van Deerlin V, Chen-Plotkin AS, Caspell-Garcia C, Waligórska T, Taylor P, Shah N, Pan S, Zero P, Frasier M, Marek K, Kieburtz K, Jennings D, Tanner CM, Simuni T, Singleton A, Toga AW, Chowdhury S, Trojanowski JQ, Shaw LM, Parkinson's Progression Marker Initiative Abstract The development of biomarkers to predict the progressi...περισσότερα »

Small temporal pole encephalocele: A hidden cause of "normal" MRI temporal lobe epilepsy.

Alexandros G. SfakianakisστοHead and NeckΠριν από 36 δευτερόλεπτα
*Small temporal pole encephalocele: A hidden cause of "normal" MRI temporal lobe epilepsy.* Epilepsia. 2016 Mar 28; Authors: Toledano R, Jiménez-Huete A, Campo P, Poch C, García-Morales I, Gómez Angulo JC, Coras R, Blümcke I, Álvarez-Linera J, Gil-Nagel A Abstract OBJECTIVE: Small temporal pole encephalocele (STPE) can be the pathologic substrate of epilepsy in a subgroup of patients with noninformative magnetic resonance imaging (MRI). Herein, we analyzed the clinical, neurophysiologic, and radiologic features of the epilepsy found in 22 patients with STPE, and the frequency of ...περισσότερα »

In This Issue

from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/230UzjL via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Issue Information

Cover of this issue. In vivo luciferase assay to evaluate peritoneal dissemination in mice. See also Takahashi, R., et al. (pages 341–346 of this issue). from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1LZDgvo via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report

The Japan Diabetes Society/Japanese Cancer Association Joint Committee on Diabetes and Cancer published its first report in July 2013 on the epidemiological assessment of the associations of diabetes with cancer risk/prognosis, the common risk factors for diabetes and cancer, and cancer risk associated with diabetes treatment. The Joint Committee continued its work to assess the […]

Gene Aberrations for Precision Medicine against Lung Adenocarcinoma

Abstract Lung adenocarcinoma (LADC), the most frequent histological type of lung cancer, is often triggered by an aberration in a driver oncogene in tumor cells. Examples of such aberrations are EGFR mutation and ALK fusion. LADC harboring such mutations can be treated with anti-cancer drugs that target the aberrant gene products. Additional oncogene aberrations, including […]

MYC translocation and/or BCL2 protein expression are associated with poor prognosis in diffuse large B-cell lymphoma

Abstract Genomic alterations and protein expression levels have been established as prognostic factors for survival in patients with diffuse large B-cell lymphoma (DLBCL). In particular, double-hit DLBCL (DHL), which exhibits translocations in MYC and BCL2 and/or BCL6, is known to be associated with a poor prognosis. However, the clinical significance of gene alterations and protein […]

Statement published on pairing smoking cessation with lung cancer screening

Researchers, including an associate professor from the Medical University of South Carolina Hollings Cancer Center, say smokers who go to a doctor to be screened for lung cancer should also be encouraged to quit smoking during their visit, according to a… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/25vYZkY via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 […]

Researchers found new clue to fighting acute myeloid leukaemia

A study led by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has uncovered a new clue that may help fight acute myeloid leukaemia (AML), the most common form of cancer of the blood… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1pK3rM2 via IFTTT Medicine by Alexandros […]

Annular erythematous eruption with a high response to mosquito bite

from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1qhXiHN via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Orange pigmentation spots on the sole may be from a stink bug

from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1Ry90EN via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Levels of immunoglobulin E specific to the major food allergen and chemokine (C-C motif) ligand (CCL)17/thymus and activation regulated chemokine and CCL22/macrophage-derived chemokine in infantile atopic dermatitis on Ishigaki Island

Abstract Atopic dermatitis (AD) is a multifactorial T-helper (Th)2-mediated skin disease frequently associated with elevated serum immunoglobulin (Ig)E and food allergy is also a Th2- and IgE-mediated adverse immunological reaction. Our previous study indicated the relation of egg allergy history and disease severity of AD. Thus, the purpose of the study was to investigate the […]

In This Issue

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/230UzjL via IFTTT

Issue Information

Cover of this issue. In vivo luciferase assay to evaluate peritoneal dissemination in mice. See also Takahashi, R., et al. (pages 341–346 of this issue). from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1LZDgvo via IFTTT

Report of the Japan diabetes society/Japanese cancer association joint committee on diabetes and cancer, Second report

The Japan Diabetes Society/Japanese Cancer Association Joint Committee on Diabetes and Cancer published its first report in July 2013 on the epidemiological assessment of the associations of diabetes with cancer risk/prognosis, the common risk factors for diabetes and cancer, and cancer risk associated with diabetes treatment. The Joint Committee continued its work to assess the […]

Gene Aberrations for Precision Medicine against Lung Adenocarcinoma

Abstract Lung adenocarcinoma (LADC), the most frequent histological type of lung cancer, is often triggered by an aberration in a driver oncogene in tumor cells. Examples of such aberrations are EGFR mutation and ALK fusion. LADC harboring such mutations can be treated with anti-cancer drugs that target the aberrant gene products. Additional oncogene aberrations, including […]

MYC translocation and/or BCL2 protein expression are associated with poor prognosis in diffuse large B-cell lymphoma

Abstract Genomic alterations and protein expression levels have been established as prognostic factors for survival in patients with diffuse large B-cell lymphoma (DLBCL). In particular, double-hit DLBCL (DHL), which exhibits translocations in MYC and BCL2 and/or BCL6, is known to be associated with a poor prognosis. However, the clinical significance of gene alterations and protein […]

IJMS, Vol. 17, Pages 457: Meta-Analysis on Associations of RGS1 and IL12A Polymorphisms with Celiac Disease Risk

The pathogenesis of celiac disease (CD) has been related to polymorphisms in the regulator of G-protein signaling 1 (RGS1) and interleukin-12 A (IL12A) genes, but the existing findings are inconsistent. Our aim is to investigate the associations of two single-nucleotide polymorphisms (SNPs) (rs2816316 in RGS1 and rs17810546 in IL12A) with CD risk using meta-analysis. We […]

IJMS, Vol. 17, Pages 463: Exploring Erythropoietin and G-CSF Combination Therapy in Chronic Stroke Patients

Erythropoietin (EPO) and granulocyte-colony stimulating factor (G-CSF) are known to have neuroprotective actions. Based on previous reports showing the synergistic effects of EPO+G-CSF combination therapy in experimental models, we investigated the safety of EPO+G-CSF combination therapy in patients with chronic stroke. In a pilot study, 3 patients were treated with EPO and G-CSF for 5 […]

IJMS, Vol. 17, Pages 473: Fluorescence-Lifetime Imaging Microscopy for Visualization of Quantum Dots’ Endocytic Pathway

Accumulation of carboxylated polyethylene glycol (PEG) CdSe/ZnSquantum dots (QDs) has been monitored in living fibroblasts using confocal microscopy for fluorescence intensity and fluorescence-lifetime imaging (FLIM). The wide range of mean photoluminescence (PL) lifetime values was observed for the intracellular QDs in different intracellular microenvironment, which revealed structural heterogeneity of endosomes and enabled the distinguishing among […]

Statement published on pairing smoking cessation with lung cancer screening

Researchers, including an associate professor from the Medical University of South Carolina Hollings Cancer Center, say smokers who go to a doctor to be screened for lung cancer should also be encouraged to quit smoking during their visit, according to a… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/25vYZkY via IFTTT

Researchers found new clue to fighting acute myeloid leukaemia

A study led by researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) has uncovered a new clue that may help fight acute myeloid leukaemia (AML), the most common form of cancer of the blood… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1pK3rM2 via IFTTT

Annular erythematous eruption with a high response to mosquito bite

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1qhXiHN via IFTTT

Orange pigmentation spots on the sole may be from a stink bug

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Ry90EN via IFTTT

Levels of immunoglobulin E specific to the major food allergen and chemokine (C-C motif) ligand (CCL)17/thymus and activation regulated chemokine and CCL22/macrophage-derived chemokine in infantile atopic dermatitis on Ishigaki Island

Abstract Atopic dermatitis (AD) is a multifactorial T-helper (Th)2-mediated skin disease frequently associated with elevated serum immunoglobulin (Ig)E and food allergy is also a Th2- and IgE-mediated adverse immunological reaction. Our previous study indicated the relation of egg allergy history and disease severity of AD. Thus, the purpose of the study was to investigate the […]

Relationship between androgenetic alopecia and cardiovascular risk factors according to BASP classification in Koreans

Abstract There have been many studies on the relationship between androgenetic alopecia (AGA) and cardiovascular risk factors, but the study results were inconsistent and research on AGA in Asians remains insufficient. This study investigated the relationship between Korean AGA and various cardiovascular risk factors, considering life habits, type of hair loss and sex. We investigated […]

Generalized keratosis pilaris-like eruptions in a chronic myelogenous leukemia patient treated with nilotinib

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1qhXgiS via IFTTT

[Current issues on gastroesophageal reflux disease].

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα
Related Articles *[Current issues on gastroesophageal reflux disease].* Korean J Gastroenterol. 2014 Sep 25;64(3):127-32 Authors: Kim JH, Kim BJ, Kim SW, Kim SE, Kim YS, Sung HY, Oh TH, Jeong ID, Park MI, Korean Society of Neurogastroenterology and Motility, GERD and Esophageal Function Research Committee Abstract Gastroesophageal reflux disease (GERD) is one of the most common problems in gastrointestinal disorders. With the increase in our understanding on the pathophysiology of GERD along with the development of proton pump inhibitors, the diagnostic and therapeutic approaches... περισσότερα »

Prevalence of gastro-esophageal reflux disease in patients with difficult to control asthma and effect of proton pump inhibitor therapy on asthma symptoms, reflux symptoms, pulmonary function and requirement for asthma medications.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 45 δευτερόλεπτα
[image: http:--http://ift.tt/21TaD4F] Related Articles *Prevalence of gastro-esophageal reflux disease in patients with difficult to control asthma and effect of proton pump inhibitor therapy on asthma symptoms, reflux symptoms, pulmonary function and requirement for asthma medications.* J Postgrad Med. 2014 Jul-Sep;60(3):282-6 Authors: Sandur V, Murugesh M, Banait V, Rathi PM, Bhatia SJ, Joshi JM, Kate A Abstract BACKGROUND: The hypothesis that GER can trigger or exacerbate asthma is supported by several clinical trials that have shown amelioration in asthma symptoms and/or an ... περισσότερα »

Radiation-Induced Liver Injury Mimicking Metastatic Disease in a Patient With Esophageal Cancer: Correlation of Positron Emission Tomography/Computed Tomography With Magnetic Resonance Imaging and Literature Review.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 46 δευτερόλεπτα
*Radiation-Induced Liver Injury Mimicking Metastatic Disease in a Patient With Esophageal Cancer: Correlation of Positron Emission Tomography/Computed Tomography With Magnetic Resonance Imaging and Literature Review.* J Comput Assist Tomogr. 2016 Mar 29; Authors: Rabe TM, Yokoo T, Meyer J, Kernstine KH, Wang D, Khatri G Abstract Post-radiation therapy evaluation of distal esophageal cancers with positron emission tomography/computed tomography can be problematic. Differentiation of recurrent neoplasm from postradiation changes is difficult in areas of fluorodeoxyglucose avidity i... περισσότερα »

Non-surgical versus surgical treatment for oesophageal cancer.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 46 δευτερόλεπτα
*Non-surgical versus surgical treatment for oesophageal cancer.* Cochrane Database Syst Rev. 2016 Mar 29;3:CD011498 Authors: Best LM, Mughal M, Gurusamy KS Abstract BACKGROUND: Oesophageal cancer is the sixth most common cause of cancer-related mortality in the world. Currently surgery is the recommended treatment modality when possible. However, it is unclear whether non-surgical treatment options is equivalent to oesophagectomy in terms of survival. OBJECTIVES: To assess the benefits and harms of non-surgical treatment versus oesophagectomy for people with oesophageal cancer. SE... περισσότερα »

Effects of Minimally Invasive Esophagectomy and Open Esophagectomy on Circulating Tumor Cell Level in Elderly Patients with Esophageal Cancer.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 46 δευτερόλεπτα
*Effects of Minimally Invasive Esophagectomy and Open Esophagectomy on Circulating Tumor Cell Level in Elderly Patients with Esophageal Cancer.* World J Surg. 2016 Mar 28; Authors: Wang HB, Guo Q, Li YH, Sun ZQ, Li TT, Zhang WX, Xiang SS, Li HF Abstract OBJECTIVE: To investigate the effects of minimally invasive esophagectomy (MIE) and open esophagectomy (OE) on circulating tumor cell (CTC) level of elderly patients with esophageal cancer (EC). METHODS: A total of 78 elderly EC patients who aged over 64 years were divided into the MIE group (n = 40) and the OE group (n = 38). CTC ... περισσότερα »

Esophageal reconstruction: posterior mediastinal or retrosternal route.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 46 δευτερόλεπτα
*Esophageal reconstruction: posterior mediastinal or retrosternal route.* J Surg Res. 2016 Apr;201(2):364-9 Authors: Yang J, Xu C, Lian D, Ye S, Zeng Z, Liu D, Zhuang C Abstract BACKGROUND: Although posterior mediastinal (PM) route and retrosternal (RS) route have been used for reconstruction after minimally invasive esophagectomy (MIE), the optimal route remains controversial. This study reviewed our experiences with McKeown MIEs for esophageal cancer and aimed to investigate which route was better for esophageal reconstruction. MATERIALS AND METHODS: From December 2011 to Decembe... περισσότερα »

Neoadjuvant chemoradiotherapy may increase the risk of severe anastomotic complications after esophagectomy with cervical anastomosis.

Alexandros G. SfakianakisστοThe OesophagusΠριν από 46 δευτερόλεπτα
*Neoadjuvant chemoradiotherapy may increase the risk of severe anastomotic complications after esophagectomy with cervical anastomosis.* Langenbecks Arch Surg. 2016 Mar 28; Authors: Klevebro F, Friesland S, Hedman M, Tsai JA, Lindblad M, Rouvelas I, Lundell L, Nilsson M Abstract PURPOSE: Neoadjuvant chemoradiotherapy (nCRT) improves long-term survival for patients with esophageal cancer. On the other hand, there are indications that nCRT may increase the risk for postoperative morbidity. The aims of this study were to estimate the radiation exposure to the site of anastomosis on ...περισσότερα »

High-dose-rate brachytherapy using molds for lip and oral cavity tumors.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 46 δευτερόλεπτα
Related Articles *High-dose-rate brachytherapy using molds for lip and oral cavity tumors.* Radiat Oncol. 2015;10:81 Authors: Unetsubo T, Matsuzaki H, Takemoto M, Katsui K, Hara M, Katayama N, Waki T, Kanazawa S, Asaumi J Abstract BACKGROUND: High-dose-rate (HDR) brachytherapy using the mold technique is a less invasive treatment for early lip and oral cavity cancer. However, limited reports exist regarding the feasibility of this method. In this retrospective study, we evaluated the outcome of this therapy and investigated its feasibility for lip and oral cavity tumors. METHODS:...περισσότερα »

Associations of rs4810485 and rs1883832 polymorphisms of CD40 gene with susceptibility and clinical findings of Behçet's disease.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 46 δευτερόλεπτα
Related Articles *Associations of rs4810485 and rs1883832 polymorphisms of CD40 gene with susceptibility and clinical findings of Behçet's disease.* Rheumatol Int. 2015 May;35(5):837-43 Authors: İnal EE, Rüstemoğlu A, İnanır A, Ekinci D, Gül Ü, Yiğit S, Ateş Ö Abstract There are evidences that besides geographic tendency, interactions between genetic and environmental factors play an essential role in the pathogenesis of Behçet's disease (BD). In this study, we have evaluated the associations between rs4810485 and rs1883832 single nucleotide polymorphism (SNP)s of CD40 gene with ...περισσότερα »

A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 46 δευτερόλεπτα
*A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.* Sensors (Basel). 2016;16(4) Authors: Martín-Ruiz ML, Máximo-Bocanegra N, Luna-Oliva L Abstract The importance of an early rehabilitation process in children with cerebral palsy (CP) is widely recognized. On the one hand, new and useful treatment tools such as rehabilitation systems based on interactive technologies have appeared for rehabilitation of gross motor movements. On the other hand, from the therapeutic point of view, performing rehabilitation exercises with the f... περισσότερα »

Ethnic admixture affects diabetes risk in native Hawaiians: the Multiethnic Cohort

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 49 δευτερόλεπτα
Ethnic admixture affects diabetes risk in native Hawaiians: the Multiethnic Cohort European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.32 Authors: G Maskarinec, Y Morimoto, S Jacobs, A Grandinetti, M K Mau & L N Kolonel from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1pK4ICT via IFTTT

Vitamin D and vitamin B12 deficiencies are common in patients with midgut carcinoid (SI-NET)

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 49 δευτερόλεπτα
Vitamin D and vitamin B12 deficiencies are common in patients with midgut carcinoid (SI-NET) European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.40 Authors: A Lind, B Wängberg & L Ellegård from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/25w08ZM via IFTTT

Generalized keratosis pilaris-like eruptions in a chronic myelogenous leukemia patient treated with nilotinib

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 49 δευτερόλεπτα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1qhXgiS via IFTTT

Persistent supravenous erythematous eruption-like changes from antibiotics

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 49 δευτερόλεπτα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1Ry91Ze via IFTTT

Association between folate status and cervical intraepithelial neoplasia

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 49 δευτερόλεπτα
Association between folate status and cervical intraepithelial neoplasia European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.35 Authors: W Zhao, M Hao, Y Wang, N Feng, Z Wang, W Wang, J Wang & L Ding from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1pK4Imv via IFTTT

Photolysis quantum yield measurements in the near-UV; a critical analysis of 1-(2-nitrophenyl)ethyl photochemistry

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 49 δευτερόλεπτα
Photochem. Photobiol. Sci., 2016, Accepted Manuscript DOI: 10.1039/C5PP00440C, John E. T. Corrie, Jack Kaplan, Biff Forbush, David Ogden, David Trentham None The content of this RSS Feed (c) The Royal Society of Chemistry from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1RKdwz2 via IFTTT

Inhibition of the glycaemic response by onion: a comparison between lactose-tolerant and lactose-intolerant adults

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 49 δευτερόλεπτα
Inhibition of the glycaemic response by onion: a comparison between lactose-tolerant and lactose-intolerant adults European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.44 Authors: R Hoffman, G Ranjbar & A M Madden from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/25w0box via IFTTT

Viruses, Vol. 8, Pages 93: Enterovirus Control of Translation and RNA Granule Stress Responses

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 49 δευτερόλεπτα
Enteroviruses such as poliovirus (PV) and coxsackievirus B3 (CVB3) have evolved several parallel strategies to regulate cellular gene expression and stress responses to ensure efficient expression of the viral genome. Enteroviruses utilize their encoded proteinases to take over the cellular translation apparatus and direct ribosomes to viral mRNAs. In addition, viral proteinases are used to… Continue reading Viruses, Vol. 8, Pages 93: Enterovirus Control of Translation and RNA Granule Stress Responses

Effect of whey protein on blood lipid profiles: a meta-analysis of randomized controlled trials

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 49 δευτερόλεπτα
Effect of whey protein on blood lipid profiles: a meta-analysis of randomized controlled trials European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.39 Authors: J-W Zhang, X Tong, Z Wan, Y Wang, L-Q Qin & I M Y Szeto from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1pK4Fag via IFTTT

Body composition in overweight and obese women postpartum: bioimpedance methods validated by dual energy X-ray absorptiometry and doubly labeled water

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 49 δευτερόλεπτα
Body composition in overweight and obese women postpartum: bioimpedance methods validated by dual energy X-ray absorptiometry and doubly labeled water European Journal of Clinical Nutrition advance online publication, March 30 2016. doi:10.1038/ejcn.2016.50 Authors: L Ellegård, F Bertz, A Winkvist, I Bosaeus & H K Brekke from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/25w08cc via IFTTT

A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
*A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.* Sensors (Basel). 2016;16(4) Authors: Martín-Ruiz ML, Máximo-Bocanegra N, Luna-Oliva L Abstract The importance of an early rehabilitation process in children with cerebral palsy (CP) is widely recognized. On the one hand, new and useful treatment tools such as rehabilitation systems based on interactive technologies have appeared for rehabilitation of gross motor movements. On the other hand, from the therapeutic point of view, performing rehabilitation exercises with the f... περισσότερα »

[Retrospective analysis to evaluate efficacy and safety of stereotactic radiosurgery in Cushing's disease: 24 cases and a review].

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
*[Retrospective analysis to evaluate efficacy and safety of stereotactic radiosurgery in Cushing's disease: 24 cases and a review].* Neurocirugia (Astur). 2016 Mar 22; Authors: Roldán Serrano MA, Horcajadas Almansa A, Torres Vela E, Sánchez Corral C, Moliz Molina N Abstract BACKGROUND: In the past few years, stereotactic radiosurgery (SRS) has been suggested as a good alternative, second line therapy for the management of patients with ACTH-secreting pituitary adenomas. A retrospective study has been conducted in order to evaluate the efficacy and safety of this treatment in thes...περισσότερα »

Differential miRNA-Expression as an Adjunctive Diagnostic Tool in Neuroendocrine Tumors of the Lung.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
*Differential miRNA-Expression as an Adjunctive Diagnostic Tool in Neuroendocrine Tumors of the Lung.* Cancers (Basel). 2016;8(4) Authors: Demes M, Aszyk C, Bartsch H, Schirren J, Fisseler-Eckhoff A Abstract Pulmonary malignancies with neuroendocrine differentiation represent a rare subclass of lung carcinomas, which vary in the extent of differentiation and grade of biological aggressiveness. In particular, neuroendocrine tumors are classified into well differentiated typical and atypical carcinoids as well as poorly differentiated large cell neuroendocrine and small cell lung c... περισσότερα »

Examining the Relationship between Pre-Malignant Breast Lesions, Carcinogenesis and Tumor Evolution in the Mammary Epithelium Using an Agent-Based Model.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
*Examining the Relationship between Pre-Malignant Breast Lesions, Carcinogenesis and Tumor Evolution in the Mammary Epithelium Using an Agent-Based Model.* PLoS One. 2016;11(3):e0152298 Authors: Chapa J, An G, Kulkarni SA Abstract INTRODUCTION: Breast cancer, the product of numerous rare mutational events that occur over an extended time period, presents numerous challenges to investigators interested in studying the transformation from normal breast epithelium to malignancy using traditional laboratory methods, particularly with respect to characterizing transitional and pre-mal...περισσότερα »

Synchronous uterine adenocarcinoma and leiomyosarcoma: A rare case report causing a clinical conundrum.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
*Synchronous uterine adenocarcinoma and leiomyosarcoma: A rare case report causing a clinical conundrum.* Int J Surg Case Rep. 2016 Mar 11;22:32-34 Authors: Crean KK, Huang EC, Alvarez EA Abstract INTRODUCTION: Synchronous gynecologic primary cancers are uncommon. When present, the most frequent malignancies consist of endometrial and ovarian carcinomas. Here we report an exceedingly rare case of concurrent uterine adenocarcinoma and leiomyosarcoma. CASE PRESENTATION: A 60 year-old female presented with four years of postmenopausal bleeding. An endometrial sampling showed grade 2 ... περισσότερα »

Giant Intraperitoneal Multiloculated Pseudocyst in a Male.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
*Giant Intraperitoneal Multiloculated Pseudocyst in a Male.* Case Rep Surg. 2016;2016:4974509 Authors: Oxenberg J Abstract Intraperitoneal pseudocysts are rare and may be difficult to differentiate from other malignant neoplasms. Reports of occurrences are mainly associated with long-term intraperitoneal catheter use, intraperitoneal catheter infections, or major pelvic surgery in females, although there are few reported incidences without prior trauma. We present a case of a male patient found to have a 19 × 15 × 9 cm intraperitoneal pseudocyst with other multiloculated areas an... περισσότερα »

Duodenal adenocarcinoma: Advances in diagnosis and surgical management.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
*Duodenal adenocarcinoma: Advances in diagnosis and surgical management.* World J Gastrointest Surg. 2016 Mar 27;8(3):212-21 Authors: Cloyd JM, George E, Visser BC Abstract Duodenal adenocarcinoma is a rare but aggressive malignancy. Given its rarity, previous studies have traditionally combined duodenal adenocarcinoma (DA) with either other periampullary cancers or small bowel adenocarcinomas, limiting the available data to guide treatment decisions. Nevertheless, management primarily involves complete surgical resection when technically feasible. Surgery may require pancreaticod... περισσότερα »

Novel Treatments for Rare Cancers: The U.S. Orphan Drug Act Is Delivering-A Cross-Sectional Analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
*Novel Treatments for Rare Cancers: The U.S. Orphan Drug Act Is Delivering-A Cross-Sectional Analysis.* Oncologist. 2016 Mar 28; Authors: Stockklausner C, Lampert A, Hoffmann GF, Ries M Abstract BACKGROUND: Rare cancers are a heterogeneous group of conditions with highly unmet medical needs. Although infrequent in individuals, rare cancers affect millions of people who deserve effective treatments. Therefore, we systematically analyzed the impact of the U.S. Orphan Drug Act of 1983 on delivery of novel treatments for rare cancers. METHODS: Quantitative cross-sectional analysis was...περισσότερα »

Pseudopapillary Granulosa Cell Tumor: A Case of This Rare Subtype.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
*Pseudopapillary Granulosa Cell Tumor: A Case of This Rare Subtype.* Int J Surg Pathol. 2016 Mar 28; Authors: Heller D, Haddad A, Cracchiolo B Abstract Background The pseudopapillary pattern of granulosa cell tumor is rare.Case We describe the case of a 35-year-old woman who presented with an initial diagnosis of papillary serous cystadenocarcinoma.Results Evaluation, including immunohistochemistry, led to the diagnosis of pseudopapillary granulosa cell tumor.Conclusion The pseudopapillary pattern of granulosa cell tumor is rare and must be suspected in order to utilize appropriat... περισσότερα »

A case of anti-NMDA receptor encephalitis in a woman with a NMDA-R(+) small cell lung carcinoma (SCLC).

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
*A case of anti-NMDA receptor encephalitis in a woman with a NMDA-R(+) small cell lung carcinoma (SCLC).* Clin Immunol. 2016 Mar 25; Authors: Jeraiby M, Depincé-Berger A, Bossy V, Antoine JC, Paul S Abstract The association of small cell lung cancer with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is rare. We report a 62 year old patient who developed psychiatric disorders followed by epilepsy, movement disorders, mutism and hypoventilation. Flair weighted brain MRI sequences showed diffuse high signals in the limbic system. Anti-NMDAR antibodies were detected in the ...περισσότερα »

Breast Cancer Diagnosed During Pregnancy: Adapting Recent Advances in Breast Cancer Care for Pregnant Patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *Breast Cancer Diagnosed During Pregnancy: Adapting Recent Advances in Breast Cancer Care for Pregnant Patients.* JAMA Oncol. 2015 Nov;1(8):1145-53 Authors: Loibl S, Schmidt A, Gentilini O, Kaufman B, Kuhl C, Denkert C, von Minckwitz G, Parokonnaya A, Stensheim H, Thomssen C, van Calsteren K, Poortmans P, Berveiller P, Markert UR, Amant F Abstract Breast cancer during pregnancy (BCP), although rare, is becoming more common and treatment should be as similar as possible to that for nonpregnant young patients with breast cancer. A group of specialists convened to ... περισσότερα »

Prognostic Implication of Persistent Human Papillomavirus Type 16 DNA Detection in Oral Rinses for Human Papillomavirus-Related Oropharyngeal Carcinoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *Prognostic Implication of Persistent Human Papillomavirus Type 16 DNA Detection in Oral Rinses for Human Papillomavirus-Related Oropharyngeal Carcinoma.* JAMA Oncol. 2015 Oct;1(7):907-15 Authors: Rettig EM, Wentz A, Posner MR, Gross ND, Haddad RI, Gillison ML, Fakhry C, Quon H, Sikora AG, Stott WJ, Lorch JH, Gourin CG, Guo Y, Xiao W, Miles BA, Richmon JD, Andersen PE, Misiukiewicz KJ, Chung CH, Gerber JE, Rajan SD, D'Souza G Abstract IMPORTANCE: Human papillomavirus-related oropharyngeal carcinoma (HPV-OPC) is increasing in incidence in the United States. Altho... περισσότερα »

Breast Cancer in Young Women: Rare Disease or Public Health Problem?

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *Breast Cancer in Young Women: Rare Disease or Public Health Problem?* JAMA Oncol. 2015 Oct;1(7):877-8 Authors: Rosenberg SM, Newman LA, Partridge AH PMID: 26204453 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1SmbQMN via IFTTT

Spinal intradural metastasis from scapular Ewing sarcoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *Spinal intradural metastasis from scapular Ewing sarcoma.* BMC Res Notes. 2015;8:298 Authors: Ralapanawa DM, Jayawickreme KP, Ekanayake EM, Kumarihamy KW Abstract BACKGROUND: Ewing sarcoma is a primary bone neoplasm, which is a high grade aggressive small round blue cell tumour, and is currently recognized as a part of the Ewing family of tumours. It is the most lethal bone tumor, and is a rare malignant bone tumor accounting for 10% of all primary bone tumors, and 6% of malignant bone tumors. It has an average annual incidence of 3 per 1 million, found almost e... περισσότερα »

The Endoscopic Endonasal Approach for Removal of Petroclival Chondrosarcomas.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *The Endoscopic Endonasal Approach for Removal of Petroclival Chondrosarcomas.* Neurosurg Clin N Am. 2015 Jul;26(3):453-62 Authors: Ditzel Filho LF, Prevedello DM, Dolci RL, Jamshidi AO, Kerr EE, Campbell R, Otto BA, Carrau RL Abstract Chondrosarcomas of the skull base are rare, locally invasive tumors that typically arise in the petroclival region, from degenerated chondroid cells located within the synchondrosis. Given their usually slow growth rate, they are capable of reaching sizable dimensions, promoting bone erosion and significant displacement of neurova... περισσότερα »

Surgical Techniques for Sinonasal Malignancies.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *Surgical Techniques for Sinonasal Malignancies.* Neurosurg Clin N Am. 2015 Jul;26(3):403-12 Authors: Farag A, Rosen M, Evans J Abstract Sinonasal malignancies are a rare subset of malignancies of the upper aerodigestive tract which had been traditionally approached via open techniques. This article primarily addresses a paradigm shift in endoscopic endonasal oncological resection utilizing principles of tumor disassembly and negative margins. The surgical steps to these endoscopic techniques are detailed, emphasizing principles of sound oncological resection. P...περισσότερα »

[Head and neck synovial sarcoma: a rare location: report of two cases].

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *[Head and neck synovial sarcoma: a rare location: report of two cases].* Pan Afr Med J. 2015;20:232 Authors: Kouhen F, Afif M, Benhmidou N, Rais F, El Kabous M, Khmou M, Cherradi N, Majjaoui S, Elkacemi H, Kebdani T, Benjaafar N PMID: 26140075 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1UBR2HK via IFTTT

Case Report Diffuse large B-cell lymphoma in the primary bone marrow.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *Case Report Diffuse large B-cell lymphoma in the primary bone marrow.* Genet Mol Res. 2015;14(2):6247-50 Authors: Hu Y, Chen SL, Huang ZX, Gao W, An N Abstract This study aimed to improve understanding of the diagnosis, treatment, and prognosis of primary bone marrow (PBM) diffuse large B-cell lymphoma (DLBCL), a rare illness. We report a 56-year-old man with pancytopenia and hyperbilirubinemia but without lymphadenopathy, hepatomegaly, or splenomegaly. Bone marrow aspiration, flow cytometry, biopsy, and immunohistochemistry confirmed DLBCL. Two cycles of rituxi...περισσότερα »

CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis.* Genet Mol Res. 2015;14(2):5203-9 Authors: Wang X, He Y Abstract Cytochrome P4502E1 (CYP2E1) is a key enzyme in the metabolic activation of many carcinogens, but the roles of CYP2E1 polymorphisms in cervical neoplasia (CN) are inconclusive. Published case-control cohort studies from the Pubmed, Embase, and China National Knowledge Infrastructure databases were retrieved. Data were extracted and pooled odds ratios with 95% confidence intervals were calculated. Seven studies examining 10... περισσότερα »

Tuberous sclerosis complex presenting as pulmonary lymphangioleiomyomatosis--a clinicoradiological diagnosis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *Tuberous sclerosis complex presenting as pulmonary lymphangioleiomyomatosis--a clinicoradiological diagnosis.* Pan Afr Med J. 2015;20:207 Authors: Gupta K, Goyal A, Saggar K, Banerjee A Abstract Tuberous sclerosis complex (TSC) manifests predominantly as a neurocutaneous disorder. Lymphangioleiomyomatosis (LAM) is a rare pulmonary manifestation of TSC. Imaging evaluation plays an important role in the assessment of patients with tuberous sclerosis complex. In newly diagnosed patients, it helps not only to confirm the diagnosis of TSC, but also helps in identify... περισσότερα »

[Rare ovarian tumors: report of a series of 11 cases of malignant non-epithelial ovarian tumors].

Alexandros G. SfakianakisστοHead and NeckΠριν από 49 δευτερόλεπτα
Related Articles *[Rare ovarian tumors: report of a series of 11 cases of malignant non-epithelial ovarian tumors].* Pan Afr Med J. 2015;20:174 Authors: Mamouni N, Saadi H, Erraghay S, Bouchikhi C, Banani A PMID: 26113917 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1UBR2HA via IFTTT

A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 52 δευτερόλεπτα
*A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.* Sensors (Basel). 2016;16(4) Authors: Martín-Ruiz ML, Máximo-Bocanegra N, Luna-Oliva L Abstract The importance of an early rehabilitation process in children with cerebral palsy (CP) is widely recognized. On the one hand, new and useful treatment tools such as rehabilitation systems based on interactive technologies have appeared for rehabilitation of gross motor movements. On the other hand, from the therapeutic point of view, performing rehabilitation exercises with the f... περισσότερα »

A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 52 δευτερόλεπτα
*A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.* Sensors (Basel). 2016;16(4) Authors: Martín-Ruiz ML, Máximo-Bocanegra N, Luna-Oliva L Abstract The importance of an early rehabilitation process in children with cerebral palsy (CP) is widely recognized. On the one hand, new and useful treatment tools such as rehabilitation systems based on interactive technologies have appeared for rehabilitation of gross motor movements. On the other hand, from the therapeutic point of view, performing rehabilitation exercises with the f... περισσότερα »

[Retrospective analysis to evaluate efficacy and safety of stereotactic radiosurgery in Cushing's disease: 24 cases and a review].

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
*[Retrospective analysis to evaluate efficacy and safety of stereotactic radiosurgery in Cushing's disease: 24 cases and a review].* Neurocirugia (Astur). 2016 Mar 22; Authors: Roldán Serrano MA, Horcajadas Almansa A, Torres Vela E, Sánchez Corral C, Moliz Molina N Abstract BACKGROUND: In the past few years, stereotactic radiosurgery (SRS) has been suggested as a good alternative, second line therapy for the management of patients with ACTH-secreting pituitary adenomas. A retrospective study has been conducted in order to evaluate the efficacy and safety of this treatment in thes...περισσότερα »

Differential miRNA-Expression as an Adjunctive Diagnostic Tool in Neuroendocrine Tumors of the Lung.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
*Differential miRNA-Expression as an Adjunctive Diagnostic Tool in Neuroendocrine Tumors of the Lung.* Cancers (Basel). 2016;8(4) Authors: Demes M, Aszyk C, Bartsch H, Schirren J, Fisseler-Eckhoff A Abstract Pulmonary malignancies with neuroendocrine differentiation represent a rare subclass of lung carcinomas, which vary in the extent of differentiation and grade of biological aggressiveness. In particular, neuroendocrine tumors are classified into well differentiated typical and atypical carcinoids as well as poorly differentiated large cell neuroendocrine and small cell lung c... περισσότερα »

Examining the Relationship between Pre-Malignant Breast Lesions, Carcinogenesis and Tumor Evolution in the Mammary Epithelium Using an Agent-Based Model.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
*Examining the Relationship between Pre-Malignant Breast Lesions, Carcinogenesis and Tumor Evolution in the Mammary Epithelium Using an Agent-Based Model.* PLoS One. 2016;11(3):e0152298 Authors: Chapa J, An G, Kulkarni SA Abstract INTRODUCTION: Breast cancer, the product of numerous rare mutational events that occur over an extended time period, presents numerous challenges to investigators interested in studying the transformation from normal breast epithelium to malignancy using traditional laboratory methods, particularly with respect to characterizing transitional and pre-mal...περισσότερα »

Synchronous uterine adenocarcinoma and leiomyosarcoma: A rare case report causing a clinical conundrum.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
*Synchronous uterine adenocarcinoma and leiomyosarcoma: A rare case report causing a clinical conundrum.* Int J Surg Case Rep. 2016 Mar 11;22:32-34 Authors: Crean KK, Huang EC, Alvarez EA Abstract INTRODUCTION: Synchronous gynecologic primary cancers are uncommon. When present, the most frequent malignancies consist of endometrial and ovarian carcinomas. Here we report an exceedingly rare case of concurrent uterine adenocarcinoma and leiomyosarcoma. CASE PRESENTATION: A 60 year-old female presented with four years of postmenopausal bleeding. An endometrial sampling showed grade 2 ... περισσότερα »

Giant Intraperitoneal Multiloculated Pseudocyst in a Male.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
*Giant Intraperitoneal Multiloculated Pseudocyst in a Male.* Case Rep Surg. 2016;2016:4974509 Authors: Oxenberg J Abstract Intraperitoneal pseudocysts are rare and may be difficult to differentiate from other malignant neoplasms. Reports of occurrences are mainly associated with long-term intraperitoneal catheter use, intraperitoneal catheter infections, or major pelvic surgery in females, although there are few reported incidences without prior trauma. We present a case of a male patient found to have a 19 × 15 × 9 cm intraperitoneal pseudocyst with other multiloculated areas an... περισσότερα »

Duodenal adenocarcinoma: Advances in diagnosis and surgical management.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
*Duodenal adenocarcinoma: Advances in diagnosis and surgical management.* World J Gastrointest Surg. 2016 Mar 27;8(3):212-21 Authors: Cloyd JM, George E, Visser BC Abstract Duodenal adenocarcinoma is a rare but aggressive malignancy. Given its rarity, previous studies have traditionally combined duodenal adenocarcinoma (DA) with either other periampullary cancers or small bowel adenocarcinomas, limiting the available data to guide treatment decisions. Nevertheless, management primarily involves complete surgical resection when technically feasible. Surgery may require pancreaticod... περισσότερα »

Novel Treatments for Rare Cancers: The U.S. Orphan Drug Act Is Delivering-A Cross-Sectional Analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
*Novel Treatments for Rare Cancers: The U.S. Orphan Drug Act Is Delivering-A Cross-Sectional Analysis.* Oncologist. 2016 Mar 28; Authors: Stockklausner C, Lampert A, Hoffmann GF, Ries M Abstract BACKGROUND: Rare cancers are a heterogeneous group of conditions with highly unmet medical needs. Although infrequent in individuals, rare cancers affect millions of people who deserve effective treatments. Therefore, we systematically analyzed the impact of the U.S. Orphan Drug Act of 1983 on delivery of novel treatments for rare cancers. METHODS: Quantitative cross-sectional analysis was...περισσότερα »

Pseudopapillary Granulosa Cell Tumor: A Case of This Rare Subtype.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
*Pseudopapillary Granulosa Cell Tumor: A Case of This Rare Subtype.* Int J Surg Pathol. 2016 Mar 28; Authors: Heller D, Haddad A, Cracchiolo B Abstract Background The pseudopapillary pattern of granulosa cell tumor is rare.Case We describe the case of a 35-year-old woman who presented with an initial diagnosis of papillary serous cystadenocarcinoma.Results Evaluation, including immunohistochemistry, led to the diagnosis of pseudopapillary granulosa cell tumor.Conclusion The pseudopapillary pattern of granulosa cell tumor is rare and must be suspected in order to utilize appropriat... περισσότερα »

A case of anti-NMDA receptor encephalitis in a woman with a NMDA-R(+) small cell lung carcinoma (SCLC).

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
*A case of anti-NMDA receptor encephalitis in a woman with a NMDA-R(+) small cell lung carcinoma (SCLC).* Clin Immunol. 2016 Mar 25; Authors: Jeraiby M, Depincé-Berger A, Bossy V, Antoine JC, Paul S Abstract The association of small cell lung cancer with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is rare. We report a 62 year old patient who developed psychiatric disorders followed by epilepsy, movement disorders, mutism and hypoventilation. Flair weighted brain MRI sequences showed diffuse high signals in the limbic system. Anti-NMDAR antibodies were detected in the ...περισσότερα »

Breast Cancer Diagnosed During Pregnancy: Adapting Recent Advances in Breast Cancer Care for Pregnant Patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
Related Articles *Breast Cancer Diagnosed During Pregnancy: Adapting Recent Advances in Breast Cancer Care for Pregnant Patients.* JAMA Oncol. 2015 Nov;1(8):1145-53 Authors: Loibl S, Schmidt A, Gentilini O, Kaufman B, Kuhl C, Denkert C, von Minckwitz G, Parokonnaya A, Stensheim H, Thomssen C, van Calsteren K, Poortmans P, Berveiller P, Markert UR, Amant F Abstract Breast cancer during pregnancy (BCP), although rare, is becoming more common and treatment should be as similar as possible to that for nonpregnant young patients with breast cancer. A group of specialists convened to ... περισσότερα »

Prognostic Implication of Persistent Human Papillomavirus Type 16 DNA Detection in Oral Rinses for Human Papillomavirus-Related Oropharyngeal Carcinoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
Related Articles *Prognostic Implication of Persistent Human Papillomavirus Type 16 DNA Detection in Oral Rinses for Human Papillomavirus-Related Oropharyngeal Carcinoma.* JAMA Oncol. 2015 Oct;1(7):907-15 Authors: Rettig EM, Wentz A, Posner MR, Gross ND, Haddad RI, Gillison ML, Fakhry C, Quon H, Sikora AG, Stott WJ, Lorch JH, Gourin CG, Guo Y, Xiao W, Miles BA, Richmon JD, Andersen PE, Misiukiewicz KJ, Chung CH, Gerber JE, Rajan SD, D'Souza G Abstract IMPORTANCE: Human papillomavirus-related oropharyngeal carcinoma (HPV-OPC) is increasing in incidence in the United States. Altho... περισσότερα »

Breast Cancer in Young Women: Rare Disease or Public Health Problem?

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
Related Articles *Breast Cancer in Young Women: Rare Disease or Public Health Problem?* JAMA Oncol. 2015 Oct;1(7):877-8 Authors: Rosenberg SM, Newman LA, Partridge AH PMID: 26204453 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1SmbQMN via IFTTT

Spinal intradural metastasis from scapular Ewing sarcoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
Related Articles *Spinal intradural metastasis from scapular Ewing sarcoma.* BMC Res Notes. 2015;8:298 Authors: Ralapanawa DM, Jayawickreme KP, Ekanayake EM, Kumarihamy KW Abstract BACKGROUND: Ewing sarcoma is a primary bone neoplasm, which is a high grade aggressive small round blue cell tumour, and is currently recognized as a part of the Ewing family of tumours. It is the most lethal bone tumor, and is a rare malignant bone tumor accounting for 10% of all primary bone tumors, and 6% of malignant bone tumors. It has an average annual incidence of 3 per 1 million, found almost e... περισσότερα »

The Endoscopic Endonasal Approach for Removal of Petroclival Chondrosarcomas.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
Related Articles *The Endoscopic Endonasal Approach for Removal of Petroclival Chondrosarcomas.* Neurosurg Clin N Am. 2015 Jul;26(3):453-62 Authors: Ditzel Filho LF, Prevedello DM, Dolci RL, Jamshidi AO, Kerr EE, Campbell R, Otto BA, Carrau RL Abstract Chondrosarcomas of the skull base are rare, locally invasive tumors that typically arise in the petroclival region, from degenerated chondroid cells located within the synchondrosis. Given their usually slow growth rate, they are capable of reaching sizable dimensions, promoting bone erosion and significant displacement of neurova... περισσότερα »

Surgical Techniques for Sinonasal Malignancies.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
Related Articles *Surgical Techniques for Sinonasal Malignancies.* Neurosurg Clin N Am. 2015 Jul;26(3):403-12 Authors: Farag A, Rosen M, Evans J Abstract Sinonasal malignancies are a rare subset of malignancies of the upper aerodigestive tract which had been traditionally approached via open techniques. This article primarily addresses a paradigm shift in endoscopic endonasal oncological resection utilizing principles of tumor disassembly and negative margins. The surgical steps to these endoscopic techniques are detailed, emphasizing principles of sound oncological resection. P...περισσότερα »

[Head and neck synovial sarcoma: a rare location: report of two cases].

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
Related Articles *[Head and neck synovial sarcoma: a rare location: report of two cases].* Pan Afr Med J. 2015;20:232 Authors: Kouhen F, Afif M, Benhmidou N, Rais F, El Kabous M, Khmou M, Cherradi N, Majjaoui S, Elkacemi H, Kebdani T, Benjaafar N PMID: 26140075 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1UBR2HK via IFTTT

Case Report Diffuse large B-cell lymphoma in the primary bone marrow.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
Related Articles *Case Report Diffuse large B-cell lymphoma in the primary bone marrow.* Genet Mol Res. 2015;14(2):6247-50 Authors: Hu Y, Chen SL, Huang ZX, Gao W, An N Abstract This study aimed to improve understanding of the diagnosis, treatment, and prognosis of primary bone marrow (PBM) diffuse large B-cell lymphoma (DLBCL), a rare illness. We report a 56-year-old man with pancytopenia and hyperbilirubinemia but without lymphadenopathy, hepatomegaly, or splenomegaly. Bone marrow aspiration, flow cytometry, biopsy, and immunohistochemistry confirmed DLBCL. Two cycles of rituxi...περισσότερα »

CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
Related Articles *CYP2E1 PstI polymorphism increases cervical neoplasia risk: a meta-analysis.* Genet Mol Res. 2015;14(2):5203-9 Authors: Wang X, He Y Abstract Cytochrome P4502E1 (CYP2E1) is a key enzyme in the metabolic activation of many carcinogens, but the roles of CYP2E1 polymorphisms in cervical neoplasia (CN) are inconclusive. Published case-control cohort studies from the Pubmed, Embase, and China National Knowledge Infrastructure databases were retrieved. Data were extracted and pooled odds ratios with 95% confidence intervals were calculated. Seven studies examining 10... περισσότερα »

Tuberous sclerosis complex presenting as pulmonary lymphangioleiomyomatosis--a clinicoradiological diagnosis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 52 δευτερόλεπτα
Related Articles *Tuberous sclerosis complex presenting as pulmonary lymphangioleiomyomatosis--a clinicoradiological diagnosis.* Pan Afr Med J. 2015;20:207 Authors: Gupta K, Goyal A, Saggar K, Banerjee A Abstract Tuberous sclerosis complex (TSC) manifests predominantly as a neurocutaneous disorder. Lymphangioleiomyomatosis (LAM) is a rare pulmonary manifestation of TSC. Imaging evaluation plays an important role in the assessment of patients with tuberous sclerosis complex. In newly diagnosed patients, it helps not only to confirm the diagnosis of TSC, but also helps in identify... περισσότερα »

A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 54 δευτερόλεπτα
*A Virtual Environment to Improve the Detection of Oral-Facial Malfunction in Children with Cerebral Palsy.* Sensors (Basel). 2016;16(4) Authors: Martín-Ruiz ML, Máximo-Bocanegra N, Luna-Oliva L Abstract The importance of an early rehabilitation process in children with cerebral palsy (CP) is widely recognized. On the one hand, new and useful treatment tools such as rehabilitation systems based on interactive technologies have appeared for rehabilitation of gross motor movements. On the other hand, from the therapeutic point of view, performing rehabilitation exercises with the f... περισσότερα »

Differential miRNA-Expression as an Adjunctive Diagnostic Tool in Neuroendocrine Tumors of the Lung.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
*Differential miRNA-Expression as an Adjunctive Diagnostic Tool in Neuroendocrine Tumors of the Lung.* Cancers (Basel). 2016;8(4) Authors: Demes M, Aszyk C, Bartsch H, Schirren J, Fisseler-Eckhoff A Abstract Pulmonary malignancies with neuroendocrine differentiation represent a rare subclass of lung carcinomas, which vary in the extent of differentiation and grade of biological aggressiveness. In particular, neuroendocrine tumors are classified into well differentiated typical and atypical carcinoids as well as poorly differentiated large cell neuroendocrine and small cell lung c... περισσότερα »

Examining the Relationship between Pre-Malignant Breast Lesions, Carcinogenesis and Tumor Evolution in the Mammary Epithelium Using an Agent-Based Model.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
*Examining the Relationship between Pre-Malignant Breast Lesions, Carcinogenesis and Tumor Evolution in the Mammary Epithelium Using an Agent-Based Model.* PLoS One. 2016;11(3):e0152298 Authors: Chapa J, An G, Kulkarni SA Abstract INTRODUCTION: Breast cancer, the product of numerous rare mutational events that occur over an extended time period, presents numerous challenges to investigators interested in studying the transformation from normal breast epithelium to malignancy using traditional laboratory methods, particularly with respect to characterizing transitional and pre-mal...περισσότερα »

Synchronous uterine adenocarcinoma and leiomyosarcoma: A rare case report causing a clinical conundrum.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
*Synchronous uterine adenocarcinoma and leiomyosarcoma: A rare case report causing a clinical conundrum.* Int J Surg Case Rep. 2016 Mar 11;22:32-34 Authors: Crean KK, Huang EC, Alvarez EA Abstract INTRODUCTION: Synchronous gynecologic primary cancers are uncommon. When present, the most frequent malignancies consist of endometrial and ovarian carcinomas. Here we report an exceedingly rare case of concurrent uterine adenocarcinoma and leiomyosarcoma. CASE PRESENTATION: A 60 year-old female presented with four years of postmenopausal bleeding. An endometrial sampling showed grade 2 ... περισσότερα »

Giant Intraperitoneal Multiloculated Pseudocyst in a Male.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
*Giant Intraperitoneal Multiloculated Pseudocyst in a Male.* Case Rep Surg. 2016;2016:4974509 Authors: Oxenberg J Abstract Intraperitoneal pseudocysts are rare and may be difficult to differentiate from other malignant neoplasms. Reports of occurrences are mainly associated with long-term intraperitoneal catheter use, intraperitoneal catheter infections, or major pelvic surgery in females, although there are few reported incidences without prior trauma. We present a case of a male patient found to have a 19 × 15 × 9 cm intraperitoneal pseudocyst with other multiloculated areas an... περισσότερα »

Duodenal adenocarcinoma: Advances in diagnosis and surgical management.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
*Duodenal adenocarcinoma: Advances in diagnosis and surgical management.* World J Gastrointest Surg. 2016 Mar 27;8(3):212-21 Authors: Cloyd JM, George E, Visser BC Abstract Duodenal adenocarcinoma is a rare but aggressive malignancy. Given its rarity, previous studies have traditionally combined duodenal adenocarcinoma (DA) with either other periampullary cancers or small bowel adenocarcinomas, limiting the available data to guide treatment decisions. Nevertheless, management primarily involves complete surgical resection when technically feasible. Surgery may require pancreaticod... περισσότερα »

Novel Treatments for Rare Cancers: The U.S. Orphan Drug Act Is Delivering-A Cross-Sectional Analysis.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
*Novel Treatments for Rare Cancers: The U.S. Orphan Drug Act Is Delivering-A Cross-Sectional Analysis.* Oncologist. 2016 Mar 28; Authors: Stockklausner C, Lampert A, Hoffmann GF, Ries M Abstract BACKGROUND: Rare cancers are a heterogeneous group of conditions with highly unmet medical needs. Although infrequent in individuals, rare cancers affect millions of people who deserve effective treatments. Therefore, we systematically analyzed the impact of the U.S. Orphan Drug Act of 1983 on delivery of novel treatments for rare cancers. METHODS: Quantitative cross-sectional analysis was...περισσότερα »

Pseudopapillary Granulosa Cell Tumor: A Case of This Rare Subtype.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
*Pseudopapillary Granulosa Cell Tumor: A Case of This Rare Subtype.* Int J Surg Pathol. 2016 Mar 28; Authors: Heller D, Haddad A, Cracchiolo B Abstract Background The pseudopapillary pattern of granulosa cell tumor is rare.Case We describe the case of a 35-year-old woman who presented with an initial diagnosis of papillary serous cystadenocarcinoma.Results Evaluation, including immunohistochemistry, led to the diagnosis of pseudopapillary granulosa cell tumor.Conclusion The pseudopapillary pattern of granulosa cell tumor is rare and must be suspected in order to utilize appropriat... περισσότερα »

A case of anti-NMDA receptor encephalitis in a woman with a NMDA-R(+) small cell lung carcinoma (SCLC).

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
*A case of anti-NMDA receptor encephalitis in a woman with a NMDA-R(+) small cell lung carcinoma (SCLC).* Clin Immunol. 2016 Mar 25; Authors: Jeraiby M, Depincé-Berger A, Bossy V, Antoine JC, Paul S Abstract The association of small cell lung cancer with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is rare. We report a 62 year old patient who developed psychiatric disorders followed by epilepsy, movement disorders, mutism and hypoventilation. Flair weighted brain MRI sequences showed diffuse high signals in the limbic system. Anti-NMDAR antibodies were detected in the ...περισσότερα »

Breast Cancer Diagnosed During Pregnancy: Adapting Recent Advances in Breast Cancer Care for Pregnant Patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
Related Articles *Breast Cancer Diagnosed During Pregnancy: Adapting Recent Advances in Breast Cancer Care for Pregnant Patients.* JAMA Oncol. 2015 Nov;1(8):1145-53 Authors: Loibl S, Schmidt A, Gentilini O, Kaufman B, Kuhl C, Denkert C, von Minckwitz G, Parokonnaya A, Stensheim H, Thomssen C, van Calsteren K, Poortmans P, Berveiller P, Markert UR, Amant F Abstract Breast cancer during pregnancy (BCP), although rare, is becoming more common and treatment should be as similar as possible to that for nonpregnant young patients with breast cancer. A group of specialists convened to ... περισσότερα »

Prognostic Implication of Persistent Human Papillomavirus Type 16 DNA Detection in Oral Rinses for Human Papillomavirus-Related Oropharyngeal Carcinoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
Related Articles *Prognostic Implication of Persistent Human Papillomavirus Type 16 DNA Detection in Oral Rinses for Human Papillomavirus-Related Oropharyngeal Carcinoma.* JAMA Oncol. 2015 Oct;1(7):907-15 Authors: Rettig EM, Wentz A, Posner MR, Gross ND, Haddad RI, Gillison ML, Fakhry C, Quon H, Sikora AG, Stott WJ, Lorch JH, Gourin CG, Guo Y, Xiao W, Miles BA, Richmon JD, Andersen PE, Misiukiewicz KJ, Chung CH, Gerber JE, Rajan SD, D'Souza G Abstract IMPORTANCE: Human papillomavirus-related oropharyngeal carcinoma (HPV-OPC) is increasing in incidence in the United States. Altho... περισσότερα »

Breast Cancer in Young Women: Rare Disease or Public Health Problem?

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
Related Articles *Breast Cancer in Young Women: Rare Disease or Public Health Problem?* JAMA Oncol. 2015 Oct;1(7):877-8 Authors: Rosenberg SM, Newman LA, Partridge AH PMID: 26204453 [PubMed - indexed for MEDLINE] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1SmbQMN via IFTTT

Spinal intradural metastasis from scapular Ewing sarcoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
Related Articles *Spinal intradural metastasis from scapular Ewing sarcoma.* BMC Res Notes. 2015;8:298 Authors: Ralapanawa DM, Jayawickreme KP, Ekanayake EM, Kumarihamy KW Abstract BACKGROUND: Ewing sarcoma is a primary bone neoplasm, which is a high grade aggressive small round blue cell tumour, and is currently recognized as a part of the Ewing family of tumours. It is the most lethal bone tumor, and is a rare malignant bone tumor accounting for 10% of all primary bone tumors, and 6% of malignant bone tumors. It has an average annual incidence of 3 per 1 million, found almost e... περισσότερα »

The Endoscopic Endonasal Approach for Removal of Petroclival Chondrosarcomas.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
Related Articles *The Endoscopic Endonasal Approach for Removal of Petroclival Chondrosarcomas.* Neurosurg Clin N Am. 2015 Jul;26(3):453-62 Authors: Ditzel Filho LF, Prevedello DM, Dolci RL, Jamshidi AO, Kerr EE, Campbell R, Otto BA, Carrau RL Abstract Chondrosarcomas of the skull base are rare, locally invasive tumors that typically arise in the petroclival region, from degenerated chondroid cells located within the synchondrosis. Given their usually slow growth rate, they are capable of reaching sizable dimensions, promoting bone erosion and significant displacement of neurova... περισσότερα »

Surgical Techniques for Sinonasal Malignancies.

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
Related Articles *Surgical Techniques for Sinonasal Malignancies.* Neurosurg Clin N Am. 2015 Jul;26(3):403-12 Authors: Farag A, Rosen M, Evans J Abstract Sinonasal malignancies are a rare subset of malignancies of the upper aerodigestive tract which had been traditionally approached via open techniques. This article primarily addresses a paradigm shift in endoscopic endonasal oncological resection utilizing principles of tumor disassembly and negative margins. The surgical steps to these endoscopic techniques are detailed, emphasizing principles of sound oncological resection. P...περισσότερα »

[Head and neck synovial sarcoma: a rare location: report of two cases].

Alexandros G. SfakianakisστοHead and NeckΠριν από 56 δευτερόλεπτα
Related Articles *[Head and neck synovial sarcoma: a rare location: report of two cases].* Pan Afr Med J. 2015;20:232 Authors: Kouhen F, Afif M, Benhmidou N, Rais F, El Kabous M, Khmou M, Cherradi N, Majjaoui S, Elkacemi H, Kebdani T, Benjaafar N PMID: 26140075 [PubMed - indexed for MEDLINE] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1UBR2HK via IFTTT

Congenital limb deficiency classification and nomenclature: The need for a consensus

Alexandros G. SfakianakisστοEvolution of a geneΠριν από 58 δευτερόλεπτα
After the thalidomide epidemic in the early 1960s, many jurisdictions developed congenital anomaly surveillance systems. Congenital limb deficiencies can act as indicators of potential teratogens. The classification of congenital limb deficiencies is essential to determine the precise cause or causes of this anomaly. This article describes the different terminology and classification that have been used over time and the need for a consensus. While there are a variety of studies examining the epidemiology and etiology of congenital limb deficiencies, there is an inconsistent use ... περισσότερα »

[Adenocarcinoma of lung cancer with solitary metastasis to the stomach].

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 58 δευτερόλεπτα
Related Articles *[Adenocarcinoma of lung cancer with solitary metastasis to the stomach].* Korean J Gastroenterol. 2014 Sep 25;64(3):154-7 Authors: Koh SA, Lee KH Abstract Although hematogenous metastasis of cancer to the gastrointestinal track is rare, it sometime has been reported in patients with malignant melanoma and breast cancer. However, it is extremely rare for lung cancer to metastasize to the stomach, not to mention solitary gastric metastasis. Herein, the authors report a case of a 69-year-old man who was initially diagnosed with lung cancer with synchronous primary ...περισσότερα »

[Adenocarcinoma of lung cancer with solitary metastasis to the stomach].

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 58 δευτερόλεπτα
Related Articles *[Adenocarcinoma of lung cancer with solitary metastasis to the stomach].* Korean J Gastroenterol. 2014 Sep 25;64(3):154-7 Authors: Koh SA, Lee KH Abstract Although hematogenous metastasis of cancer to the gastrointestinal track is rare, it sometime has been reported in patients with malignant melanoma and breast cancer. However, it is extremely rare for lung cancer to metastasize to the stomach, not to mention solitary gastric metastasis. Herein, the authors report a case of a 69-year-old man who was initially diagnosed with lung cancer with synchronous primary ...περισσότερα »

Annular erythematous eruption with a high response to mosquito bite

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 58 δευτερόλεπτα
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1qhXiHN via IFTTT

Orange pigmentation spots on the sole may be from a stink bug

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 58 δευτερόλεπτα
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1Ry90EN via IFTTT

[Adenocarcinoma of lung cancer with solitary metastasis to the stomach].

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 58 δευτερόλεπτα
Related Articles *[Adenocarcinoma of lung cancer with solitary metastasis to the stomach].* Korean J Gastroenterol. 2014 Sep 25;64(3):154-7 Authors: Koh SA, Lee KH Abstract Although hematogenous metastasis of cancer to the gastrointestinal track is rare, it sometime has been reported in patients with malignant melanoma and breast cancer. However, it is extremely rare for lung cancer to metastasize to the stomach, not to mention solitary gastric metastasis. Herein, the authors report a case of a 69-year-old man who was initially diagnosed with lung cancer with synchronous primary ...περισσότερα »

Thyro-gastric autoimmunity in patients with differentiated thyroid cancer: a prospective study.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 1 ώρα
Related Articles *Thyro-gastric autoimmunity in patients with differentiated thyroid cancer: a prospective study.* Endocrine. 2015 May;49(1):163-9 Authors: Cicone F, Papa A, Lauri C, Tofani A, Virili C, Centanni M, Scopinaro F, Annibale B Abstract Thyro-gastric autoimmunity has not been previously evaluated in patients with differentiated thyroid cancer (DTC), although its long-term complications may be relevant for the management of DTC patients. We assessed the prevalence of gastric autoimmunity and autoimmune gastritis (AG) in patients with Hashimoto's thyroiditis (HT) and co... περισσότερα »

[Dorsal liposarcoma: a rare clinical presentation].

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *[Dorsal liposarcoma: a rare clinical presentation].* Pan Afr Med J. 2015;20:171 Authors: Agbessi O, Arrob A, Fiqhi K, Khalfi L, Nassih M, El Khatib K PMID: 26113914 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1UBR0jd via IFTTT

Effects of Minimally Invasive Esophagectomy and Open Esophagectomy on Circulating Tumor Cell Level in Elderly Patients with Esophageal Cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Effects of Minimally Invasive Esophagectomy and Open Esophagectomy on Circulating Tumor Cell Level in Elderly Patients with Esophageal Cancer.* World J Surg. 2016 Mar 28; Authors: Wang HB, Guo Q, Li YH, Sun ZQ, Li TT, Zhang WX, Xiang SS, Li HF Abstract OBJECTIVE: To investigate the effects of minimally invasive esophagectomy (MIE) and open esophagectomy (OE) on circulating tumor cell (CTC) level of elderly patients with esophageal cancer (EC). METHODS: A total of 78 elderly EC patients who aged over 64 years were divided into the MIE group (n = 40) and the OE group (n = 38). CTC ... περισσότερα »

[Rare ovarian tumors: report of a series of 11 cases of malignant non-epithelial ovarian tumors].

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *[Rare ovarian tumors: report of a series of 11 cases of malignant non-epithelial ovarian tumors].* Pan Afr Med J. 2015;20:174 Authors: Mamouni N, Saadi H, Erraghay S, Bouchikhi C, Banani A PMID: 26113917 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1UBR2HA via IFTTT

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