Peri-implant bony overgrowth
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
as a cause of revision surgery in auditory osseointegrated implantation via International Journal of Pediatric Otorhinolaryngology Publication date: July 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 86 Author(s): Jared J. Tompkins, Dana K. Petersen, Daniel D. Sharbel, Brian J. McKinnon, C. Bruce MacDonald Implantation of auditory osseointegrated implants, also known as bone-anchored hearing systems (BAHS), represents a surgical option for select pediatric patients aged 5 years or older with hearing loss. Functional indications in this patient population ... περισσότερα »
Subclinical atherosclerosis in patients with recurrent apthous stomatitis.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
Subclinical atherosclerosis in patients with recurrent apthous stomatitis Oral Dis. 2016 Apr 29; Authors: Sereflican M, Sereflican B, Dagistan E, Goksugur N, Kizildag B Abstract OBJECTIVE: Recurrent aphtous stomatitis (RAS) is an inflammatory oral mucosal disease. It has been known that inflammatory cascade plays important role in the atherosclerotic process. The aim of the study was to investigate the relationship between subclinical atherosclerotic findings and a systemic inflammatory disease, RAS. METHODS: In total, 32 patients with RAS were matched with 30 control subjects on ... περισσότερα »
Understanding the feasibility and implications of implementing early peanut introduction for prevention of peanut allergy
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα
Publication date: Available online 2 May 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Jennifer J. Koplin, Rachel L. Peters, Shyamali C. Dharmage, Lyle Gurrin, Mimi LK. Tang, Anne-Louise Ponsonby, Melanie Matheson, Alkis Togias, Gideon Lack, Katrina J. Allen BackgroundA recent randomized trial (the LEAP study) provided evidence that earlier dietary peanut introduction reduces peanut allergy prevalence in high-risk infants. However, questions remain as to how to identify and target the "at risk" population to facilitate timely introduction of peanutObjectiveTo u... περισσότερα »
House dust mite–induced asthma causes oxidative damage and DNA double-strand breaks in the lungs
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 10 δευτερόλεπτα
Publication date: Available online 2 May 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Tze Khee Chan, Xin Yi Loh, Hong Yong Peh, W.N. Felicia Tan, W.S. Daniel Tan, Na Li, Ian J.J. Tay, W.S. Fred Wong, Bevin P. Engelward BackgroundAsthma is related to airway inflammation and oxidative stress. High levels of reactive oxygen and nitrogen species can induce cytotoxic DNA damage. Nevertheless, little is known about the possible role of allergen-induced DNA damage and DNA repair as modulators of asthma-associated pathology.ObjectiveWe sought to study DNA damage and DN... περισσότερα »
Complications after surgery for benign parotid gland neoplasms
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
A prospective cohort study: [image: cover.gif?v=1&s=ed7593daaae1b7c806505d93] Abstract Background Prospective studies on procedure-specific incidences of complications after benign parotid surgery are lacking. Predictive factors for postoperative facial dysfunction remain controversial. Methods We conducted a prospective study on 132 patients undergoing parotid surgery for benign parotid neoplasms. We analyzed complication rates and assessed risk factors of postoperative transient facial palsy. Results Facial palsy rate was 40.2% on the first postoperative day, 28.3% at 2 weeks, ...περισσότερα »
Functional outcomes of sensate versus insensate free flap reconstruction in oral and oropharyngeal reconstruction: A systematic review
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
A systematic review: ABSTRACT The purposes of this article were to review the literature regarding subjective outcomes, objective functional outcomes, and objective sensation return after sensate and/or insensate free flap reconstruction of the oral cavity and oropharynx. Sensate radial forearm and anterolateral thigh free flaps tend to have better static 2-point discrimination and pressure threshold sensitivity than insensate flaps. There is insufficient evidence to draw conclusions on whether sensate flaps improve functional speech and swallowing outcomes measured by videofluoros... περισσότερα »
Right-sided aortic arch and aberrant left subclavian artery with or without a left nonrecurrent inferior laryngeal nerve
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Right-sided aortic arch and aberrant left subclavian artery with or without a left nonrecurrent inferior laryngeal nerve: [image: cover.gif?v=1&s=ed7593daaae1b7c806505d93] ABSTRACT Background In thyroid surgery, preserving the recurrent laryngeal nerve (RLN) is crucial for preventing postoperative phonatory dysfunction. Right nonrecurrent laryngeal nerves (NRLNs) are not particularly rare, and they are vulnerable to injury during surgery. This anomaly is associated with a right aberrant subclavian artery. Thus, a right-sided aortic arch with an aberrant left subclavian artery (L...περισσότερα »
HERG1 potassium channel expression in potentially malignant disorders of the oral mucosa and prognostic relevance in oral squamous cell carcinoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
HERG1 potassium channel expression in potentially malignant disorders of the oral mucosa and prognostic relevance in oral squamous cell carcinoma: [image: cover.gif?v=1&s=ed7593daaae1b7c806505d93] ABSTRACT Background HERG1 potassium channel plays a critical role in the cell proliferation. Methods HERG1 protein expression was analyzed by immunohistochemistry (IHC) in 62 patients with oral leukoplakias and 100 patients with oral squamous cell carcinomas (OSCC). HERG1 mRNA levels were assessed by real-time reverse transcriptase-polymerase chain reaction (RT-PCR) in 22 patients with ... περισσότερα »
Management of orbital invasion in sinonasal malignancies
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Management of orbital invasion in sinonasal malignancies: [image: cover.gif?v=1&s=ed7593daaae1b7c806505d93] Abstract Background Indications for preservation of orbital contents in case of malignant sinonasal tumors invading the orbit remain controversial. Methods A retrospective consecutive review was conducted of patients in a tertiary care center over a 15-year period. Results Ninety-three patients were diagnosed with a malignant tumor invading the orbit. Eighty-three were treated with curative intent of which 58 underwent surgery. Mean follow-up was 45 months. Orbital preservat... περισσότερα »
Pretreatment computed tomographic gross tumor volume as predictor of persistence of tracheostomy and percutaneous endoscopic gastrostomy tube in patients undergoing larynx preservation
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Pretreatment computed tomographic gross tumor volume as predictor of persistence of tracheostomy and percutaneous endoscopic gastrostomy tube in patients undergoing larynx preservation: [image: cover.gif?v=1&s=ed7593daaae1b7c806505d93] ABSTRACT Background Although larynx preservation affords patients improvements in laryngectomy-free survival, little has been reported regarding the functional outcomes after larynx preservation. The purpose of this study was to report the predictive value of pretreatment CT-gross tumor volume (GTV) for persistence of tracheostomy and percutaneous...περισσότερα »
One-stage reconstruction of tracheal defects with the medial femoral condyle corticoperiosteal-cutaneous free flap
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
One-stage reconstruction of tracheal defects with the medial femoral condyle corticoperiosteal-cutaneous free flap: Abstract Background The demanding anatomic and mechanical requirements make the reconstruction of long tracheal defects challenging. Multiple attempts at replacing tracheal segments are described, including the use of autologous, allogeneic, and synthetic tissues. However, the multilayer structure of the trachea and its function as a conduit for air had generally resulted in the use of nonvascularized tissue and/or multistage procedures. Methods The authors report on a... περισσότερα »
ACR Appropriateness criteria® for nasopharyngeal carcinoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
ACR Appropriateness criteria® for nasopharyngeal carcinoma: Abstract Background Nasopharyngeal carcinoma (NPC) presents mostly with locally advanced disease and is treated with multimodal therapy; however, consensus is lacking for different clinical scenarios. Methods The American College of Radiology (ACR) Appropriateness Criteria® are evidence-based guidelines for specific clinical conditions that are reviewed every 3 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journa... περισσότερα »
Evaluation of the antioxidant effects of melatonin on the larynx mucosa of rats exposed to environmental tobacco smoke
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Evaluation of the antioxidant effects of melatonin on the larynx mucosa of rats exposed to environmental tobacco smoke Abstract:This study's aim was to investigate the effect of melatonin in terms of mitigating the effects of smoking on the laryngeal mucosa of rats exposed to environmental tobacco smoke.
Clinical Otolaryngology
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Acknowledgements to reviewers Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma Evaluation of the antioxidant effects of melatonin on the larynx mucosa of rats exposed to environmental tobacco smoke Relationship between tinnitus and suicidal behaviour in Korean men and women: a cross‐sectional study Quality of life after different procedures for regional control in oral cancer patients: cross‐sectional survey Comparison of calcium alginate and carboxymethyl cellulose for nasal packing after endoscopic sinus surgery: a prospe... περισσότερα »
Evidence conflicts on iron’s role in Parkinson’s disease
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 15 δευτερόλεπτα
Experiments yield conflicting results about whether vulnerable nerve cells have too much or too little iron. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1X4pZo7 via IFTTT
Three-Dimensional Printing of Multifunctional Nanocomposites: Manufacturing Techniques and Applications
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 15 δευτερόλεπτα
The integration of nanotechnology into three-dimensional printing (3DP) offers huge potential and opportunities for the manufacturing of 3D engineered materials exhibiting optimized properties and multifunctionality. The literature relating to different 3DP techniques used to fabricate 3D structures at the macro- and microscale made of nanocomposite materials is reviewed here. The current state-of-the-art fabrication methods, their main characteristics (e.g., resolutions, advantages, limitations), the process parameters, and materials requirements are discussed. A comprehensive r... περισσότερα »
A Mitochondrion-Specific Photoactivatable Fluorescence Turn-On AIE-Based Bioprobe for Localization Super-Resolution Microscope
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 15 δευτερόλεπτα
[image: Thumbnail image of graphical abstract] *A novel mitochondrion-specific photoactivatable fluorescence turn-on bioprobe, named as o-TPE-ON+*, has been designed and readily prepared, operating in a new photoactivatable mechanism of photocyclodehydrogenation. This bioprobe exhibits unique photoactivation behavior in cells, and is applied to super-resolution imaging of mitochondrion and its dynamic investigation in both fixed and live cells under physiological conditions without any external additives. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1Z2... περισσότερα »
Ultrasmall Biocompatible WO3−x Nanodots for Multi-Modality Imaging and Combined Therapy of Cancers
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 15 δευτερόλεπτα
[image: Thumbnail image of graphical abstract] *Ultrasmall biocompatible WO3−x nanodots* with an outstanding X-ray radiation sensitization effect are prepared, and demonstrated to be applicable for multi-modality tumor imaging through computed tomography and photoacoustic imaging (PAI), and effective cancer treatment combining both photothermal therapy and radiation therapy. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1NOLAi5 via IFTTT
Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Differential expression of LOXL4 in normal and tumour tissue samples of laryngeal squamous cell carcinoma Abstract:Head and neck cancer is the sixth most common cancer in worldwide with an increasing incidence rate in recent years. LOXL4 is expressed in several tissues, and its expression has been shown to display a significant correlation with local lymph node metastasis. In this study, we aimed to explore the LOXL4 expression level in metastatic and non‐metastatic LSCC tissues and to determine its prognostic significance.
Myositis ossificans
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
is characterized by focal and acute ossification in muscles and tendons, especially in members, and general appears post-trauma via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 30 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Beatriz G. Cavalheiro, Claúdio Roberto Cernea, Lenine Garcia Brandão Introduction Myositis ossificans is a benign, non-neoplastic condition characterized by heterotropic bone formation in muscle and other soft tissues, frequently associated with direct and acute trauma.1 It gene... περισσότερα »
Acupuncture therapy as treatment for tinnitus
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
Effectiveness of acupuncture therapy as treatment for tinnitus: a randomized controlled trial via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 30 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Marcelo Yugi Doi, Simone Sayomi Tano, Adriane Rocha Schultz, Ricardo Borges, Luciana Lozza de Moraes Marchiori IntroductionTinnitus is a subjective sensation of hearing a sound in the absence of an external stimulus, which significantly worsens the quality of life in 15–25% of affected individuals.ObjectiveTo assess... περισσότερα »
Cryotherapy in dysgeusia prevention
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Evaluation of the risk factors associated with high-dose chemotherapy-induced dysgeusia in patients undergoing autologous hematopoietic stem cell transplantation: possible usefulness of cryotherapy in dysgeusia prevention.: Support Care Cancer. 2016 Apr 29; Authors: Okada N, Hanafusa T, Abe S, Sato C, Nakamura T, Teraoka K, Abe M, Kawazoe K, Ishizawa K Abstract PURPOSE: Dysgeusia is one of the sporadic adverse effects induced by chemotherapy, but it remains poorly understood. The aim of this study was to retrospectively identify the risk factors related with dysgeusia in patients... περισσότερα »
High-dose chemotherapy-induced dysgeusia
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Evaluation of the risk factors associated with high-dose chemotherapy-induced dysgeusia in patients undergoing autologous hematopoietic stem cell transplantation: possible usefulness of cryotherapy in dysgeusia prevention. Support Care Cancer. 2016 Apr 29; Authors: Okada N, Hanafusa T, Abe S, Sato C, Nakamura T, Teraoka K, Abe M, Kawazoe K, Ishizawa K Abstract PURPOSE: Dysgeusia is one of the sporadic adverse effects induced by chemotherapy, but it remains poorly understood. The aim of this study was to retrospectively identify the risk factors related with dysgeusia in patients ... περισσότερα »
Procalcitonin and C-reactive protein-based decision tree model for distinguishing PFAPA flares from acute infections.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Procalcitonin and C-reactive protein-based decision tree model for distinguishing PFAPA flares from acute infections.: Bosn J Basic Med Sci. 2016 ; Authors: Kraszewska-Głomba B, Szymańska-Toczek Z, Szenborn L Abstract As no specific laboratory test has been identified, PFAPA (periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis) remains a diagnosis of exclusion. We searched for a practical use of procalcitonin (PCT) and C-reactive protein (CRP) in distinguishing PFAPA attacks from acute bacterial and viral infections. Levels of PCT and CRP were measured in 38 pat... περισσότερα »
Go-cart injury : Pediatric laryngotracheal separation
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
following a go-cart injury via International Journal of Pediatric Otorhinolaryngology Publication date: June 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 85 Author(s): Polpatt Jitpakdee, Toby Steele, Aditi Bhuskute, Dhave Setabutr [image: Axial view of computed tomography (CT) scan revealing diffuse are in the neck.] [image: Sagittal view of CT scan upon admission.] [image: Postoperative day 4 view of anastomosis site revealing intraluminal stay suture ...] [image: Postoperative day 4 view of healing subglottic anastomosis site.] Less than one percent of... περισσότερα »
CAEPs and speech perception in children with Nurotron® cochlear implants
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
The relationship between cortical auditory evoked potentials (CAEPs) and speech perception in children with Nurotron® cochlear implants during four years of follow-up via International Journal of Pediatric Otorhinolaryngology Publication date: June 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 85 Author(s): Qianqian Guo, Yuling Li, Xinxing Fu, Hui Liu, Jing Chen, Chao Meng, Mo Long, Xueqing Chen ObjectiveThe purpose of the current study was to evaluate the relationship between the presence or absence of cortical auditory evoked potentials (CAEPs) to speec... περισσότερα »
Osteosarcoma of head and neck
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
: A retrospective study on prognostic factors from a single institute database via ScienceDirect Publication: Oral Oncology Publication date: July 2016 *Source:*Oral Oncology, Volume 58 Author(s): YiMing Chen, Qingcheng Shen, Sandhya Gokavarapu, Chengzhong Lin, Yahiya, Wei Cao, Shubhra Chauhan, Zheqi Liu, Tong Ji, Zhen Tian Highlights • The current literature is sparse in the representation of Chinese population for HNOS. • Very few retrospective studies guide treatment plan. • They are atypical to other sites and need customized therapy. ------------------------------ SummaryBackground ... περισσότερα »
World Thyroid Day is May 25th
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
World Thyroid Day is May 25th: Tens of millions of people worldwide are affected by diseases of the thyroid. The thyroid gland, butterfly-shaped and located in the middle of the lower...
Improvement in technical performance of robotic novices
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Structured training on the da Vinci Skills Simulator leads to Abstract Background The increasing use of minimally invasive techniques such as robotic-assisted devices raises the question of how to acquire robotic surgery skills. The da Vinci Skills Simulator has been demonstrated to be an effective training tool in previous reports. To date little data is available on how to acquire proficiency through simulator training. We investigated the outcome of a structured training program for robotic surgical skills by robotic novices. Methods This prospective study was conducted from Janu... περισσότερα »
Balloon dilatation in esophageal strictures in epidermolysis bullosa
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
and the role of anesthesia: Summary Esophageal involvement, which causes stricture, is a complication in epidermolysis bullosa. This causes dysphagia and malnutrition and leads to deterioration of skin lesions in these patients. The charts of 11 patients with epidermolysis bullosa and esophageal stricture who were included into dilatation program between 2003 and 2015 were retrospectively reviewed. Seven of the patients were female and four were male. The median age was 14 (2–32) years. The mean body weight of patients was 27.8 (9–51) kg. The location and number of strictured part... περισσότερα »
The pathophysiology of monosymptomatic nocturnal enuresis with special emphasis on the circadian rhythm of renal physiology
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 27 δευτερόλεπτα
Abstract Nocturnal polyuria in monosymptomatic nocturnal enuresis (MNE) has so far mainly been attributed to a disturbed circadian rhythm of renal water handling. Low vasopressin levels overnight correlate with absent maximal concentrating activity, resulting in an increased nocturnal diuresis with low urinary osmolality. Therefore, treatment with desmopressin is a rational choice. Unfortunately, 20 to 60 […]
Characterization of individual molecular adsorption geometries by atomic force microscopy: Cu-TCPP on rutile TiO2 (110)
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 27 δευτερόλεπτα
Functionalized materials consisting of inorganic substrates with organic adsorbates play an increasing role in emerging technologies like molecular electronics or hybrid photovoltaics. For such applications, the adsorption geometry of the molecules under operating conditions, e.g., ambient temperature, is crucial because it influences the electronic properties of the interface, which in turn determine the device performance. […]
Role of a Carboxyl Group in the Adsorption of Zn Porphyrins on TiO2(011)-2×1 Surface
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 27 δευτερόλεπτα
Adsorption of carboxylic-substituted Zn porphyrin molecules (COOH-ZnTPP) on the (011) surface of rutile TiO2 is examined by scanning tunneling microscopy at room temperature. The molecules are either flat, stabilized by the surface defects, or mobile with their movement limited to a reconstruction row of the substrate. Upon increasing the molecular coverage the molecules form ID […]
Electrospray deposition of organic molecules on bulk insulator surfaces
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 27 δευτερόλεπτa
Large organic molecules are of important interest for organic-based devices such as hybrid photovoltaics or molecular electronics. Knowing their adsorption geometries and electronic structures allows to design and predict macroscopic device properties. Fundamental investigations in ultra-high vacuum (UHV) are thus mandatory to analyze and engineer processes in this prospects. With increasing size, complexity or chemical […]
Permanent reduction of dissipation in nanomechanical Si resonators by chemical surface protection
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 27 δευτερόλεπτα
We report on mechanical dissipation measurements carried out on thin (∼100 nm), single-crystal silicon cantilevers with varying chemical surface termination. We find that the 1-2 nm-thick native oxide layer of silicon contributes about 85% to the friction of the mechanical resonance. We show that the mechanical friction is proportional to the thickness of the oxide […]
(Mis-)predicted subjective well-being following life events
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 27 δευτερόλεπτα
The correct prediction of how alternative states of the world affect our lives is a cornerstone of economics. We study how accurate people are in predicting their future well-being when facing major life events. Based on individual panel data, we compare people’s forecast of their life satisfaction in five years’ time to their actual realisations […]
Bioinspired polymer vesicles and membranes for biological and medical applications
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 27 δευτερόλεπτa
Biological membranes play an essential role in living organisms by providing stable and functional compartments, preserving cell architecture, whilst supporting signalling and selective transport that are mediated by a variety of proteins embedded in the membrane. However, mimicking cell membranes – to be applied in artificial systems – is very challenging because of the vast […]
Orodental status before radiation therapy of the head and neck area
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
A prospective analysis on 48 patients Cancer Radiother. 2016 Apr 27; Authors: Rouers M, Dubourg S, Bornert F, Truntzer P, Antoni D, Couchot J, Ganansia V, Bourrier C, Guihard S, Noël G Abstract PURPOSE: The treatment by irradiation of tumours of the upper head and neck tract cause many complications on the oral sphere, such as mucositis, dysphagia, asialia and tooth decay. Associated manifestations are frequent and their severity has been poorly studied. However, the patient's quality of life is directly correlated with their oral health. PATIENTS AND METHODS: We carried out an ev... περισσότερα »
HNO
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
12 Jahre Computer-Aided Surgery around the Head Zusammenfassung Dank der multidisziplinären Ausrichtung des internationalen CAS-H-Symposiums (Computer-Aided Surgery around the Head) ergaben sich in den letzten Jahren einige Fortschritte in der Medizintechnologie, welche oft von der Industrie übernommen wurden. In Bern konnten viele Entwicklungen und Erfahrungen auf dem Gebiet der computergestützten Chirurgie, gerade durch die fördernde Wirkung des CAS-H-Meetings gemacht werden. Planungs- und Simulationsmethoden in der Mund-, Kiefer- und Gesichtschirurgie sowie der HNO-Heilkunde wurd... περισσότερα »
Dose Escalation Versus Standard in Laryngopharyngeal Cancers
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Dose Escalation Versus Standard in Laryngopharyngeal Cancers: *Conditions*: Malignant Neoplasm of Oropharynx Stage III; Malignant Neoplasm of Larynx Stage III; Malignant Neoplasm of Hypopharynx Stage III; Malignant Neoplasm of Oropharynx Stage IVa; Malignant Neoplasm of Oropharynx Stage IVb; Malignant Neoplasm of Larynx Stage IV; Malignant Neoplasm of Hypopharynx Stage IVa; Malignant Neoplasm of Hypopharynx Stage IVb *Interventions*: Radiation: Escalated Dose; Radiation: Standard Dose *Sponsor*: Tata Medical Center ArmsAssigned Interventions Active Compar... περισσότερα »
Tannic Acid as a Potential Modulator of Norfloxacin Resistance in Staphylococcus Aureus Overexpressing norA
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Tannic Acid as a Potential Modulator of Norfloxacin Resistance in Staphylococcus Aureus Overexpressing norA: *Background:* Tannins have shown inhibitory effects against pathogenic bacteria, and these properties make tannins potential modifying agents in bacterial resistance. *Methods:* The minimum inhibitory concentration (MIC) of tannic acid (TA), gallic acid (GA) and norfloxacin (Nor) against *Staphylococcus aureus* SA-1119 (NorA-effluxing strain) was determined using broth microdilution tests. To assess the modulation of antibiotic resistance, the MIC of Nor was determined in gro... περισσότερα »
Self-Administered Domiciliary tDCS Treatment for Tinnitus
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
A Double-Blind Sham-Controlled Study: by Petteri Hyvärinen, Antti Mäkitie, Antti A. Aarnisalo Transcranial direct current stimulation (tDCS) has shown potential for providing tinnitus relief, although positive effects have usually been observed only during a short time period after treatment. In recent studies the focus has turned from one-session experiments towards multi-session treatment studies investigating long-term outcomes with double-blinded and sham-controlled study designs. Traditionally, tDCS has been administered in a clinical setting by a healthcare professional but ... περισσότερα »
Inherent Directionality Determines Spatial Release from Masking at the Tympanum in a Vertebrate with Internally Coupled Ears
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Inherent Directionality Determines Spatial Release from Masking at the Tympanum in a Vertebrate with Internally Coupled Ears: AbstractIn contrast to humans and other mammals, many animals have internally coupled ears that function as inherently directional pressure-gradient receivers. Two important but unanswered questions are to what extent and how do animals with such ears exploit spatial cues in the perceptual analysis of noisy and complex acoustic scenes? This study of Cope’s gray treefrog (*Hyla chrysoscelis*) investigated how the inherent directionality of internally coupled ... περισσότερα »
Characteristics of Auditory Processing Disorders
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 33 δευτερόλεπτα
Systematic Review: Purpose The purpose of this review article is to describe characteristics of auditory processing disorders (APD) by evaluating the literature in which children with suspected or diagnosed APD were compared with typically developing children and to determine whether APD must be regarded as a deficit specific to the auditory modality or as a multimodal deficit. Method Six electronic databases were searched for peer-reviewed studies investigating children with (suspected) APD in comparison with typically developing peers. Relevant studies were independently review... περισσότερα »
Journal of Speech, Language, and Hearing Research
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 33 δευτερόλεπτα
Embedded Instruction Improves Vocabulary Learning During Automated Storybook Reading Among High-Risk Preschoolers Purpose We investigated a small-group intervention designed to teach vocabulary and comprehension skills to preschoolers who were at risk for language and reading disabilities. These language skills are important and reliable predictors of later academic achievement. Method Preschoolers heard prerecorded stories 3 times per week over the course of a school year. A cluster randomized design was used to evaluate the effects of hearing storybooks with and without embedded vo... περισσότερα »
Assessing Measurement Invariance for Spanish Sentence Repetition and Morphology Elicitation Tasks
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 33 δευτερόλεπτα
Assessing Measurement Invariance for Spanish Sentence Repetition and Morphology Elicitation Tasks: Purpose The purpose of this study was to evaluate evidence supporting the construct validity of two grammatical tasks (sentence repetition, morphology elicitation) included in the Spanish Screener for Language Impairment in Children (Restrepo, Gorin, & Gray, 2013). We evaluated if the tasks measured the targeted grammatical skills in the same way across predominantly Spanish-speaking children with typical language development and those with primary language impairment. Method A mult... περισσότερα »
The Effects of Age and Preoral Sensorimotor Cues on Anticipatory Mouth Movement During Swallowing
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
The Effects of Age and Preoral Sensorimotor Cues on Anticipatory Mouth Movement During Swallowing: Purpose The aim of this study was to investigate the effects of preoral sensorimotor cues on anticipatory swallowing/eating-related mouth movements in older and younger adults. It was hypothesized that these cues are essential to timing anticipatory oral motor patterns, and these movements are delayed in older as compared with younger adults. Method Using a 2 × 2 repeated-measures design, eating-related lip, jaw, and hand movements were recorded from 24 healthy older (ages 70–85 year... περισσότερα »
Functional Near-Infrared Spectroscopy Brain Imaging Investigation of Phonological Awareness and Passage Comprehension Abilities in Adult Recipients of Cochlear Implants
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
Functional Near-Infrared Spectroscopy Brain Imaging Investigation of Phonological Awareness and Passage Comprehension Abilities in Adult Recipients of Cochlear Implants: Purpose The aim of this study was to examine how the brains of individuals with cochlear implants (CIs) respond to spoken language tasks that underlie successful language acquisition and processing. Method During functional near-infrared spectroscopy imaging, CI recipients with hearing impairment (n = 10, mean age: 52.7 ± 17.3 years) and controls with normal hearing (n = 10, mean age: 50.6 ± 17.2 years) completed ... περισσότερα »
Multidimensional Approach to the Development of a Mandarin Chinese–Oriented Sound Test
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
Multidimensional Approach to the Development of a Mandarin Chinese–Oriented Sound Test: Purpose Because the Ling six-sound test is based on American English phonemes, it can yield unreliable results when administered to non-English speakers. In this study, we aimed to improve specifically the diagnostic palette for Mandarin Chinese users by developing an adapted version of the Ling six-sound test. Method To determine the set of testing sounds, we performed an exhaustive acoustic and statistical analysis in which we considered not only the general acoustic properties but also the ... περισσότερα »
Intelligibility Measures for Adults With Parkinson's Disease, Adults With Multiple Sclerosis, and Healthy Controls
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 36 δευτερόλεπτα
Comparison of Purpose This study obtained judgments of sentence intelligibility using orthographic transcription for comparison with previously reported intelligibility judgments obtained using a visual analog scale (VAS) for individuals with Parkinson's disease and multiple sclerosis and healthy controls (K. Tjaden, J. E. Sussman, & G. E. Wilding, 2014). Method Speakers read Harvard sentences in habitual, clear, loud, and slow conditions. Sentence stimuli were equated for peak intensity and mixed with multitalker babble. A total of 50 listeners orthographically transcribed sen... περισσότερα »
Sentence Repetition Accuracy in Adults With Developmental Language Impairment
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 36 δευτερόλεπτα
Interactions of Participant Capacities and Sentence Structures: Purpose We asked whether sentence repetition accuracy could be explained by interactions of participant processing limitations with the structures of the sentences. We also tested a prediction of the procedural deficit hypothesis (Ullman & Pierpont, 2005) that adjuncts are more difficult than arguments for individuals with developmental language impairment (DLI). Method Forty-four young adults participated, 21 with DLI. The sentence repetition task varied sentence length and the use of arguments and adjuncts. We also ... περισσότερα »
Dysarthria in Adults With Cerebral Palsy
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 36 δευτερόλεπτα
Clinical Presentation and Impacts on Communication: Purpose Although dysarthria affects the large majority of individuals with cerebral palsy (CP) and can substantially complicate everyday communication, previous research has provided an incomplete picture of its clinical features. We aimed to comprehensively describe characteristics of dysarthria in adults with CP and to elucidate the impact of dysarthric symptoms on parameters relevant for communication. Method Forty-two adults with CP underwent speech assessment by means of standardized auditory rating scales. Listening experi... περισσότερα »
The Production of Complement Clauses in Children With Language Impairment
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 36 δευτερόλεπτα
The Production of Complement Clauses in Children With Language Impairment: Purpose The purpose of this research was to provide a comprehensive description of complement-clause production in children with language impairment. Complement clauses were examined with respect to types of complement structure produced, verb use, and both semantic and syntactic accuracy. Method A group of 17 children with language impairment (mean age = 6;10 [years; months]) was compared with a group of 17 younger children with typical language development (mean age = 4;6). Examples of both nonfinite comp... περισσότερα »
The Amsterdam Inventory for Auditory Disability and Handicap (AIADH)
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Reevaluation of the Amsterdam Inventory for Auditory Disability and Handicap Using Item Response Theory by Boeschen Hospers J, Smits N, Smits C, et al. via Journal of Speech,Language,and Hearing Research Current Issue Purpose We reevaluated the psychometric properties of the Amsterdam Inventory for Auditory Disability and Handicap (AIADH; Kramer, Kapteyn, Festen, & Tobi, 1995) using item response theory. Item response theory describes item functioning along an ability continuum. Method Cross-sectional data from 2,352 adults with and without hearing impairment, ages 18–70 years, were a... περισσότερα »
Height exposure on postural reactions
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Influence of virtual height exposure on postural reactions to support surface translations via Gait & Posture Publication date: June 2016 *Source:*Gait & Posture, Volume 47 Author(s): Taylor W. Cleworth, Romeo Chua, J. Timothy Inglis, Mark G. Carpenter As fear of falling is related to the increased likelihood of falls, it is important to understand the effects of threat-related factors (fear, anxiety and confidence) on dynamic postural reactions. Previous studies designed to examine threat effects on dynamic postural reactions have methodological limitations and lack a comprehensive a... περισσότερα »
Auditory Nerve Recovery Function in Cochlear Implant Surgery
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
with Local Anesthesia and Sedation versus General Anesthesia: *Objective:* To analyze auditory nerve recovery function (REC), comparing the results after local anesthesia and sedation with those after general anesthesia. *Methods:* This was a prospective, cross-sectional and descriptive study in a tertiary referral center hospital. We included all patients (37 ears) who underwent surgery for cochlear implant under either general anesthesia or local anesthesia and sedation during 3 years. REC was measured according to the function of 3 components, ‘T0', ‘A' and ‘tau', and was taken f... περισσότερα »
Over 11% Efficiency in Tandem Polymer Solar Cells Featured by a Low-Band-Gap Polymer with Fine-Tuned Properties
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 41 δευτερόλεπτα
[image: Thumbnail image of graphical abstract] *Highly efficient polymer solar cells with tandem structure* are fabricated by using two excellent photovoltaic polymers and a high transparent intermediate recombination layer. Power conversion efficiencies over 11% can be realized featured by a low-band-gap polymer with fine-tuned properties. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1NOLzuC via IFTTT
Nitrogen-Doped Porous Carbon Nanosheets Templated from g-C3N4 as Metal-Free Electrocatalysts for Efficient Oxygen Reduction Reaction
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 41 δευτερόλεπτα
[image: Thumbnail image of graphical abstract] *Nitrogen-doped porous carbon nanosheets (N-CNS)* are synthesized by hydrothermal carbon coating of g-C3N4 nanosheets followed by high-temperature treatment in N2. g-C3N4 serves as a template, nitrogen source, and porogen in the synthesis. This approach yields N-CNS with a high nitrogen content and comparable oxygen reduction reaction catalytic activities to commercial Pt/C catalysts in alkaline media. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1Z2MFDK via IFTTT
Downsized Sheath–Core Conducting Fibers for Weavable Superelastic Wires, Biosensors, Supercapacitors, and Strain Sensors
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 41 δευτερόλεπτα
[image: Thumbnail image of graphical abstract] *Hair-like-diameter superelastic conducting fibers*, comprising a buckled carbon nanotube sheath on a rubber core, are fabricated, characterized, and deployed as weavable wires, biosensors, supercapacitors, and strain sensors. These downsized sheath–core fibers provide the demonstrated basis for glucose sensors, supercapacitors, and electrical interconnects whose performance is undegraded by giant strain, as well as ultrafast strain sensors that exploit strain-dependent capacitance changes. from Biomedical Engineering via xlomafota13 ... περισσότερα »
White Electroluminescent Lighting Device Based on a Single Quantum Dot Emitter
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 41 δευτερόλεπτα
[image: Thumbnail image of graphical abstract] *Using a single emitter of Cu−Ga−S/ZnS quantum dots*, all-solution-processed white electroluminescent lighting device that not only exhibits the record quantities of 1007 cd m−2 in luminance and 1.9% in external quantum efficiency but also possesses satisfactorily high color rendering indices of 83−88 is demonstrated. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1Z2MDvw via IFTTT
Cloning Nacre's 3D Interlocking Skeleton in Engineering Composites to Achieve Exceptional Mechanical Properties
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 41 δευτερόλεπτα
[image: Thumbnail image of graphical abstract] *Ceramic/polymer composite equipped with 3D interlocking skeleton (3D IL)* is developed through a simple freeze-casting method, exhibiting exceptionally light-weight, high strength, toughness, and shock resistance. Long-range crack energy dissipation enabled by 3D interlocking structure is considered as the primary reinforcing mechanism for such superior properties. The smart composite design strategy should hold a place in developing future structural engineering materials. from Biomedical Engineering via xlomafota13 on Inoreader ht... περισσότερα »
Sulfur Doping Induces Strong Ferromagnetic Ordering in Graphene: Effect of Concentration and Substitution Mechanism
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 41 δευτερόλεπτα
[image: Thumbnail image of graphical abstract] *In this work, imprinting ferromagnetism to graphene structure* is reported by substitution of carbon atoms with sulfur. S-doped graphene (4.2 at%) shows strong ferromagnetic properties with saturation magnetization exceeding 5.5 emu g−1 at 2 K, which is among the highest values reported for any *sp*-based system. Remarkable magnetic response is attributed to delocalization of electrons from sulfur injected into the graphene conduction band. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1Z2MFDD via IFTTT
Smartphone-based digits-in-noise hearing test
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 41 δευτερόλεπτα
Development and validation of a smartphone-based digits-in-noise hearing test in South African English: 10.3109/14992027.2016.1172269<br>Jenni-Marí Potgieter Abstract *Objective:* The objective of this study was to develop and validate a smartphone-based digits-in-noise hearing test for South African English. *Design:* Single digits (0–9) were recorded and spoken by a first language English female speaker. Level corrections were applied to create a set of homogeneous digits with steep speech recognition functions. A smartphone application was created to utilize 120 digit-triplet... περισσότερα »
Flow-resistant Tubes Used for Semi-occluded Vocal Tract Voice Training and Therapy
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Characterization of via Voice Publication date: Available online 28 April 2016 *Source:*Journal of Voice Author(s): Simeon L. Smith, Ingo R. Titze ObjectivesThis study aimed to characterize the pressure-flow relationship of tubes used for semi-occluded vocal tract voice training/therapy, as well as to answer these major questions: (1) What is the relative importance of tube length to tube diameter? (2) What is the range of oral pressures achieved with tubes at phonation flow rates? (3) Does mouth configuration behind the tubes matter?MethodsPlastic tubes of various diameters and leng... περισσότερα »
MP4 Therapy Videos on Adherence to Voice Therapy Home Practice in Children With Dysphonia
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Effect of via Voice Publication date: Available online 28 April 2016 *Source:*Journal of Voice Author(s): Maia N. Braden, Eva van Leer Objectives/HypothesisVoice disorders in children are often treated with behavioral voice therapy, which requires home practice of exercises. Previous studies with adults demonstrated increased practice frequency when patients were given videos of a clinician and patient performing therapy tasks. The purpose of this study was to determine whether videos of practice exercises would increase adherence to therapy in children.Study DesignThe study used a r... περισσότερα »
Optokinetic Stimulation on Perceptual and Postural Symptoms
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
The Effect of Optokinetic Stimulation on Perceptual and Postural Symptoms in Visual Vestibular Mismatch Patients: by Angelique Van Ombergen, Astrid J. Lubeck, Vincent Van Rompaey, Leen K. Maes, John F. Stins, Paul H. Van de Heyning, Floris L. Wuyts, Jelte E. Bos Background Vestibular patients occasionally report aggravation or triggering of their symptoms by visual stimuli, which is called visual vestibular mismatch (VVM). These patients therefore experience discomfort, disorientation, dizziness and postural unsteadiness. Objective Firstly, we aimed to get a better insight in t... περισσότερα »
Somatising Tendency
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Descriptive Epidemiology of Somatising Tendency: Findings from the CUPID Study: by Sergio Vargas-Prada, David Coggon, Georgia Ntani, Karen Walker-Bone, Keith T. Palmer, Vanda E. Felli, Raul Harari, Lope H. Barrero, Sarah A. Felknor, David Gimeno, Anna Cattrell, Matteo Bonzini, Eleni Solidaki, Eda Merisalu, Rima R. Habib, Farideh Sadeghian, M. Masood Kadir, Sudath S. P. Warnakulasuriya, Ko Matsudaira, Busisiwe Nyantumbu, Malcolm R. Sim, Helen Harcombe, Ken Cox, Leila M. M. Sarquis, Maria H. Marziale, Florencia Harari, Rocio Freire, Natalia Harari, Magda V. Monroy, Leonardo A. Quint... περισσότερα »
Suppression tuning of spontaneous otoacoustic emissions
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Frequency selectivity of the human cochlea: via Hearing Research Publication date: Available online 29 April 2016 *Source:*Hearing Research Author(s): Geoffrey A. Manley, Pim van Dijk Frequency selectivity is a key functional property of the inner ear and since hearing research began, the frequency resolution of the human ear has been a central question. In contrast to animal studies, which permit invasive recording of neural activity, human studies must rely on indirect methods to determine hearing selectivity. Psychophysical studies, which used masking of a tone by other sounds, ind...περισσότερα »
Frequency lowering (FL) devices have been around for decades, offering signal processing designed to improve audibility of sounds for listeners with high-frequency hearing loss
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
An Update on Modified Verification Approaches for Frequency Lowering Devices: Frequency lowering (FL) devices have been around for decades, offering signal processing designed to improve audibility of sounds for listeners with high-frequency hearing loss. Within the literature, several papers offer a review of the rationale and evidence on FL for managing high-frequency hearing loss.
Tigecycline for Patients with Hospital-Acquired Pneumonia
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Efficacy and Safety of *Background:* Tigecycline is an antibiotic agent with a broad spectrum, which has an antibacterial effect against many multidrug-resistant organisms. However, its clinical efficacy in the treatment of hospital-acquired pneumonia (HAP) is disputed. *Materials and Methods:* In this report, a systematic review and meta-analysis were conducted to evaluate the efficacy and safety of tigecycline for the treatment of HAP. The primary outcome was the rate of clinical cure, and the secondary outcomes were mortality and adverse events (AEs). *Results:* Four trials i... περισσότερα »
Assessing the Impact of Electronic Capture of Patient Reported Outcomes in Radiation Oncology
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 59 δευτερόλεπτα
*Condition*: Patients With Lung, Breast, Head and Neck, or Pelvic Malignancies *Intervention*: Other: Survey *Sponsor*: Abramson Cancer Center of the University of Pennsylvania *Recruiting* - verified April 2016 from #ORL via xlomafota13 on Inoreader http://ift.tt/24ix362 via IFTTT
Dose Escalation Versus Standard in Laryngopharyngeal Cancers
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 59 δευτερόλεπτα
*Conditions*: Malignant Neoplasm of Oropharynx Stage III; Malignant Neoplasm of Larynx Stage III; Malignant Neoplasm of Hypopharynx Stage III; Malignant Neoplasm of Oropharynx Stage IVa; Malignant Neoplasm of Oropharynx Stage IVb; Malignant Neoplasm of Larynx Stage IV; Malignant Neoplasm of Hypopharynx Stage IVa; Malignant Neoplasm of Hypopharynx Stage IVb *Interventions*: Radiation: Escalated Dose; Radiation: Standard Dose *Sponsor*: Tata Medical Center *Recruiting* - verified April 2016 from #ORL via xlomafota13 on Inoreader http://ift.tt/1QNhFSh via IFTTT
12 Jahre Computer-Aided Surgery around the Head
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 59 δευτερόλεπτα
Zusammenfassung Dank der multidisziplinären Ausrichtung des internationalen CAS-H-Symposiums (Computer-Aided Surgery around the Head) ergaben sich in den letzten Jahren einige Fortschritte in der Medizintechnologie, welche oft von der Industrie übernommen wurden. In Bern konnten viele Entwicklungen und Erfahrungen auf dem Gebiet der computergestützten Chirurgie, gerade durch die fördernde Wirkung des CAS-H-Meetings gemacht werden. Planungs- und Simulationsmethoden in der Mund-, Kiefer- und Gesichtschirurgie sowie der HNO-Heilkunde wurden entwickelt und klinisch getestet. Weitere C... περισσότερα »
Assessing the Impact of Electronic Capture of Patient Reported Outcomes in Radiation Oncology
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Condition*: Patients With Lung, Breast, Head and Neck, or Pelvic Malignancies *Intervention*: Other: Survey *Sponsor*: Abramson Cancer Center of the University of Pennsylvania *Recruiting* - verified April 2016 from #ENT via xlomafota13 on Inoreader http://ift.tt/24ix362 via IFTTT
Dose Escalation Versus Standard in Laryngopharyngeal Cancers
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Conditions*: Malignant Neoplasm of Oropharynx Stage III; Malignant Neoplasm of Larynx Stage III; Malignant Neoplasm of Hypopharynx Stage III; Malignant Neoplasm of Oropharynx Stage IVa; Malignant Neoplasm of Oropharynx Stage IVb; Malignant Neoplasm of Larynx Stage IV; Malignant Neoplasm of Hypopharynx Stage IVa; Malignant Neoplasm of Hypopharynx Stage IVb *Interventions*: Radiation: Escalated Dose; Radiation: Standard Dose *Sponsor*: Tata Medical Center *Recruiting* - verified April 2016 from #ENT via xlomafota13 on Inoreader http://ift.tt/1QNhFSh via IFTTT
pH-Triggered Reversible Multiple Protein-Polymer Conjugation Based on Molecular Recognition
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Polymer conjugation for protein-based therapeutics has been developed extensively, but it still suffers from conjugation leading to decrease in protein activity and generates complexes with limited diversity due to general classical systems only incorporating one protein per each complex. Here we introduce a site-specific noncovalent protein-polymer conjugation, which can reduce the heterogeneity of the conjugates […]
Clean carbon nanotubes coupled to superconducting impedance-matching circuits
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Coupling carbon nanotube devices to microwave circuits offers a significant increase in bandwidth (BW) and signal-to-noise ratio. These facilitate fast non-invasive readouts important for quantum information processing, shot noise and correlation measurements. However, creation of a device that unites a low-disorder nanotube with a low-loss microwave resonator has so far remained a challenge, due to […]
A randomized trial of videoconference-delivered cognitive behavioral therapy for survivors of breast cancer with self-reported cognitive dysfunction
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
BACKGROUND Long-term chemotherapy-related cognitive dysfunction (CRCD) affects a large number of cancer survivors. To the authors’ knowledge, to date there is no established treatment for this survivorship problem. The authors herein report results of a small randomized controlled trial of a cognitive behavioral therapy (CBT), Memory and Attention Adaptation Training (MAAT), compared with an attention […]
A Boy with Disseminated Tuberculosis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The post A Boy with Disseminated Tuberculosis appeared first on Welcome to Avens. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SImv5e via IFTTT
Influence of Folic Acid on Neural Connectivity during Dorsal Root Ganglion Neurogenesis
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
The vitamin folic acid (FA) is essential for DNA synthesis, repair and methylation, and for methionine synthesis. Although it is necessary for neural development, recent studies suggest a possible link between excess maternal supplemental FA intake and adverse interferences with single-carbon metabolism and neural development. Insufficient FA early in brain development can lead to failure of the neural tube closure, but the consequences of too much intake have not been fully investigated. Plasma FA concentrations can increase greatly with dietary supplementation. To model the deve... περισσότερα »
Has the quality of reporting in periodontology changed in 14 years? a systematic review
Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Quality of reporting randomised controlled trials in periodontology has been poor. Consolidated Standards of Reporting Trials guidelines and an extension for non-pharmacologic trials (CONSORT–NPE), were introduced to aid in improving this. Aims Assess the quality of reporting in periodontology, changes over the last 14 years, and adherence to CONSORT–NPE. Methods RCTs in humans, published in three periodontal journals, from 2013-2015 were included. Search was conducted through Medline, Embase and hand searching. Results 173 full text articles included. Two reviewers scree... περισσότερα »
12 Jahre Computer-Aided Surgery around the Head
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Zusammenfassung Dank der multidisziplinären Ausrichtung des internationalen CAS-H-Symposiums (Computer-Aided Surgery around the Head) ergaben sich in den letzten Jahren einige Fortschritte in der Medizintechnologie, welche oft von der Industrie übernommen wurden. In Bern konnten viele Entwicklungen und Erfahrungen auf dem Gebiet der computergestützten Chirurgie, gerade durch die fördernde Wirkung des CAS-H-Meetings gemacht werden. Planungs- und Simulationsmethoden in der Mund-, Kiefer- und Gesichtschirurgie sowie der HNO-Heilkunde wurden entwickelt und klinisch getestet. Weitere C... περισσότερα »
Risky skull surgery done for ritual reasons 6,000 years ago
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 1 ώρα
Some ancient skull surgeries hinged on ritual, not on medical treatment. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/24io7gT via IFTTT
Has the quality of reporting in periodontology changed in 14 years? a systematic review
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 2 ώρες
Abstract Quality of reporting randomised controlled trials in periodontology has been poor. Consolidated Standards of Reporting Trials guidelines and an extension for non-pharmacologic trials (CONSORT–NPE), were introduced to aid in improving this. Aims Assess the quality of reporting in periodontology, changes over the last 14 years, and adherence to CONSORT–NPE. Methods RCTs in humans, published in three periodontal journals, from 2013-2015 were included. Search was conducted through Medline, Embase and hand searching. Results 173 full text articles included. Two reviewers s... περισσότερα »
Breaking BRAF(V600E)-drug resistance by stressing mitochondria
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Until recently, advanced stage melanoma was considered an untreatable disease. However, tangible hope for patients has now become attached to small molecule inhibitors targeting the melanoma oncogene BRAF(V600E) and approaches to unleash the immune system against these tumors. Still, not every patient will be given respite by these treatments, and the ultimate goal of […]
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