Head and Neck Medicine by Alexandros G.Sfakianakis: OtoRhinoLaryngology & Medicine,New Articles,May 4th,2016

Τετάρτη 4 Μαΐου 2016

OtoRhinoLaryngology & Medicine,New Articles,May 4th,2016

The Effect of Assisted Exercise Frequency on Bone Strength in Very Low Birth Weight Preterm Infants: A Randomized Control Trial

sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 9 δευτερόλεπτα

Abstract We aimed to assess whether a twice daily assisted exercise interventional program will have a greater effect on bone strength compared to a once daily intervention or no intervention in very low birth weight (VLBW) preterm infants. Thirty-four very VLBW preterm infants (mean BW 1217 ± 55 g and mean gestational age 28.6 ± […]

Role of Gastrectomy in the Management of Gastric PreMalignancies – A Review of Current Literature and Illust rative Case Report

The post Role of Gastrectomy in the Management of Gastric PreMalignancies – A Review of Current Literature and Illustrative Case Report appeared first on Welcome to Avens. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1rTq6HF via IFTTT

Insights, attitudes, and perceptions about asthma and its treatment: a multinational survey of patients from Europe and Canada

Asthma surveys completed within the past 10 years in the Americas and the Asia-Pacific region have shown significant underassessment of asthma severity in addition to undertreatment of asthma and have suggeste… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Y7dyGh via IFTTT

Reconstruction of Complex Defects of Lower Extremities Using Thinned Free Muscle Flaps

Abstract Background Bulky appearance is a major shortcoming after surface coverage using free muscle flaps. The one-stage thinning procedure at the time of transfer can improve the appearance and avoid additional debulking surgery. We present our experiences in the reconstruction of complex lower extremity defects using thinned free muscle flaps. Methods Latissimus dorsi muscle flaps […]

Auditory System Plasticity And Regeneration

Auditory System Plasticity And Regeneration | voaveonow.ru … the Auditory System; Auditory plasticity in the periphery – hair cell regeneration; Central … from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Y7j77I via IFTTT

Thousands of North-East smokers tried to quit after seeing hard-hitting campaign – The Northern Echo (registration)

The Northern Echo (registration) Thousands of North-East smokers tried to quit after seeing hard-hitting campaign The Northern Echo (registration) A CAMPAIGN warning how smoking can cause 16 types of cancer has inspired thousands of North-East smokers to quit. Fresh’s Quit 16 campaign, supported by Cancer Research UK, highlighted the toll that smoking-related cancers have on […]

Reconstruction of Complex Defects of Lower Extremities Using Thinned Free Muscle Flaps

sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 10 δευτερόλεπτα

Insights, attitudes, and perceptions about asthma and its treatment: a multinational survey of patients from Europe and Canada

Asthma surveys completed within the past 10 years in the Americas and the Asia-Pacific region have shown significant underassessment of asthma severity in addition to undertreatment of asthma and have suggeste… from Allergy via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Y7dyGh via IFTTT

Evaluation of a modified in-plane ultrasound technique for routine arterial catheterisation: A prospective observational study.

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 12 δευτερόλεπτα

No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/26S704h via IFTTT

Protective effects of continuous positive airway pressure on a nonventilated lung during one-lung ventilation: A prospective laboratory study in rats.

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 12 δευτερόλεπτα

BACKGROUND: The use of one-lung ventilation (OLV) to facilitate intrathoracic surgery is a cause of lung injury. OBJECTIVE: We hypothesised that application of continuous positive airway pressure (CPAP) to a nonventilated lung during OLV would prevent alveolar hypoxia and blood flow shift from the nonventilated to the ventilated lung, thereby attenuating lung injury. DESIGN: Controlled animal study. SETTINGS: University laboratory. STUDY PARTICIPANTS: Adult male Sprague-Dawley rats (n = 4 to 8 per group, depending on experiments). INTERVENTIONS: Rats were alternately assigned to one... περισσότερα »

Pre-augmentation soft tissue expansion improves scaffold-based vertical bone regeneration – a randomized study in dogs

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 12 δευτερόλεπτα

[image: cover.gif?v=1&s=705296a249cff94ae911375e] Abstract Objective Soft tissue (ST) dehiscence with graft exposure is a frequent complication of vertical augmentation. Flap dehiscence is caused by failure to achieve tension-free primary wound closure and by the impairment of flap microcirculation due to surgical trauma. Soft tissue expansion (STE) increases ST quality and quantity prior to reconstructive surgery. We hypothesized that flap preconditioning using STE would reduce the incidence of ST complications after bone augmentation and that optimized ST healing would improve...περισσότερα »

Friction behavior of ceramic injection-molded (CIM) brackets

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 12 δευτερόλεπτα

Abstract Objectives Bracket material, bracket design, archwire material, and ligature type are critical modifiers of friction behavior during archwire-guided movement of teeth. We designed this in vitro study to compare the friction losses of ceramic injection-molded (CIM) versus pressed-ceramic (PC) and metal injection-molded (MIM) brackets—used with different ligatures and archwires—during archwire-guided retraction of a canine. Methods Nine bracket systems were compared, including five CIM (Clarity™ and Clarity™ ADVANCED, both by 3M Unitek; discovery® pearl by Dentaurum; Glam ...περισσότερα »

Expression of VO 2peak in Children and Youth, with Special Reference to Allometric Scaling

Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα

Abstract The aim of this review was to highlight research that has focused on examining expressions of peak oxygen uptake (VO2peak) in children and youth, with special reference to allometric scaling. VO2peak is considered the highest VO2 during an increasing workload treadmill or bicycle ergometer test until volitional termination. We have reviewed scholarly works identified from PubMed, One Search, EBSCOhost and Google Scholar that examined VO2peak in absolute units (L·min−1), relative units [body mass, fat-free mass (FFM)], and allometric expressions [mass, height, lean body ma...περισσότερα »

Minimizing Head Acceleration in Soccer: A Review of the Literature

Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα

Abstract Physicians and healthcare professionals are often asked for recommendations on how to keep athletes safe during contact sports such as soccer. With an increase in concussion awareness and concern about repetitive subconcussion, many parents and athletes are interested in mitigating head acceleration in soccer, so we conducted a literature review on factors that affect head acceleration in soccer. We searched electronic databases and reference lists to find studies using the keywords 'soccer' OR 'football' AND 'head acceleration'. Because of a lack of current research in so... περισσότερα »

Combined Aerobic and Resistance Training Effects on Glucose Homeostasis, Fitness, and Other Major Health Indices: A Review of Current Guidelines

Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα

Abstract The combination of aerobic and resistance training (AER + RES) is recommended by almost every major organization to improve health-related risk factors associated with sedentary behavior. Since the release of the Physical Activity Guidelines for Americans in 2008, several large well-controlled trials and ancillary reports have been published that provide further insight into the effects of AER + RES on health-related outcomes. The current manuscript examines the literature on the effects of AER + RES on major clinical outcomes, including glucose homeostasis, cardiorespira...περισσότερα »

Is There a Biomechanical Link Between Patellofemoral Pain and Osteoarthritis? A Narrative Review

Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα

Abstract The patellofemoral (PF) joint is the knee compartment most commonly affected by osteoarthritis (OA). Even mild PF OA is associated with considerable pain and functional limitations. Despite its prevalence and impact, little is understood of the etiology or structural and functional features of PF OA. The clinical symptoms of PF OA, such as anterior knee pain during stair ambulation and squatting, share many similarities with PF pain in adolescents and young adults. PF joint OA is most commonly diagnosed in people aged >40 years, many of whom report a history of PF pain. A...περισσότερα »

Movement Patterns and Muscular Function Before and After Onset of Sports-Related Groin Pain: A Systematic Review with Meta-analysis

Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα

Abstract Background Sports-related groin pain (SRGP) is a common entity in rotational sports such as football, rugby and hockey, accounting for 12–18 % of injuries each year, with high recurrence rates and often prolonged time away from sport. Objective This systematic review synthesises movement and muscle function findings to better understand deficits and guide rehabilitation. Study Selection Prospective and retrospective cross-sectional studies investigating muscle strength, flexibility, cross-sectional area, electromyographic activation onset and magnitude in patients with S... περισσότερα »

A novel de novo dominant negative mutation in DNM1L impairs mitochondrial fission and presents as childhood epileptic encephalopathy

Alexandros G. SfakianakisστοEvolution of a geneΠριν από 30 δευτερόλεπτα

*DNM1L* encodes dynamin-related protein 1 (DRP1/DLP1), a key component of the mitochondrial fission machinery that is essential for proper functioning of the mammalian brain. Previously reported probands with de novo missense mutations in *DNM1L* presented in the first year of life with severe encephalopathy and refractory epilepsy, with several dying within the first several weeks after birth. In contrast, we report identical novel missense mutations in *DNM1L* in two unrelated probands who experienced normal development for several years before presenting with refractory focal ... περισσότερα »

Death from supine asphyxia in late onset pompe disease: Two patients

Alexandros G. SfakianakisστοEvolution of a geneΠριν από 30 δευτερόλεπτα

from Genes via ola Kala on Inoreader http://ift.tt/24pvzqx via IFTTT

Influence of hearing loss and cognitive abilities on language development in CHARGE Syndrome

Alexandros G. SfakianakisστοEvolution of a geneΠριν από 30 δευτερόλεπτα

Hearing loss and cognitive delay are frequently occurring features in CHARGE syndrome that may contribute to impaired language development. However, not much is known about language development in patients with CHARGE syndrome. In this retrospective study, hearing loss, cognitive abilities, and language development are described in 50 patients with CHARGE syndrome. After informed consent was given, data were collected from local medical files. Most patients (38.3%; 18/47 patients) had moderate hearing loss (41–70 dB) and 58.5% (24/41 patients) had an IQ below 70. The mean languag...περισσότερα »

Dental Fillings

Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 33 δευτερόλεπτα

The post Dental Fillings appeared first on Family Dentistry and Cosmetic Surgery Clinic. from #Dental via xlomafota13 on Inoreader http://ift.tt/26S2Nhe via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

The surgical management of cephalalgia.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

Purpose of review: Management of headache disorders is not part of most craniomaxillofacial surgery practices; however there are certain indications for surgical management of headaches by the craniomaxillofacial surgeon. Recent findings: Migraine headaches are the most amenable to surgical management and while the exact mechanism of migraine is unknown, a central or peripheral trigger such as compressive neuropathy of trigeminal nerve branches leading to neurogenic inflammation has been suggested. The primary management for episodic migraine headache should be lifestyle modificatio... περισσότερα »

Update on mandibular condylar fracture management.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 36 δευτερόλεπτα

Purpose of review: Fractures of the mandibular condyle have provided a lasting source of controversy in the field of facial trauma. Concerns regarding facial nerve injury as well as reasonable functional outcomes with closed management led to a reluctance to treat with an open operative intervention. This article reviews how incorporating new technologies and surgical methods have changed the treatment paradigm. Recent findings: Multiple large studies and meta-analyses continue to demonstrate superior outcomes for condylar fractures when managed surgically. Innovations, including en... περισσότερα »

Does the amount of egg protein and type of preparation influence tolerability of baked egg products and potential development of regular egg tolerance in egg-allergic children?

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 50 δευτερόλεπτα

Publication date: May 2016 *Source:*Annals of Allergy, Asthma & Immunology, Volume 116, Issue 5 Author(s): Stephanie A. Leonard from Allergy\Immunology via ola Kala on Inoreader http://ift.tt/1ru4Ibw via IFTTT

What is the current role of biologics in the management of patients with severe refractory asthma?

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 50 δευτερόλεπτα

Publication date: May 2016 *Source:*Annals of Allergy, Asthma & Immunology, Volume 116, Issue 5 Author(s): Steven Draikiwicz, John Oppenheimer from Allergy\Immunology via ola Kala on Inoreader http://ift.tt/1TKrBjP via IFTTT

Leaving home: Helping teens with allergic conditions become independent

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 50 δευτερόλεπτα

Publication date: May 2016 *Source:*Annals of Allergy, Asthma & Immunology, Volume 116, Issue 5 Author(s): David R. Stukus, Mervat Nassef, Marc Rubin from Allergy\Immunology via ola Kala on Inoreader http://ift.tt/1TKrAfW via IFTTT

Translational Immunology: Mechanisms and Pharmacologic Approaches

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 50 δευτερόλεπτα

Publication date: May 2016 *Source:*Annals of Allergy, Asthma & Immunology, Volume 116, Issue 5 Author(s): Mitchell H. Grayson from Allergy\Immunology via ola Kala on Inoreader http://ift.tt/1ru4Ibq via IFTTT

A sensitive electrochemiluminescent aptasensor based on perylene derivatives as a novel co-reaction accelerator for signal amplification

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 51 δευτερόλεπτα

[image: S09565663.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): Yan-Qing Yu, Hai-Yu Zhang, Ya-Qin Chai, Ruo Yuan, Ying Zhuo Herein, a novel signal amplification strategy was designed using the perylene derivative as the co-reaction accelerator toward graphene-CdTe quantum dots (G-CdTe)/S2O82− system to construct a highly sensitive electrochemiluminescent (ECL) aptasensor for thrombin (TB) detection. Firstly, the G-CdTe nanocomposites were prepared by one-step method of in situ generating CdTe quantum dots onto the surface of the ...περισσότερα »

Sensitivity Enhancement of Bead-based Electrochemical Impedance Spectroscopy (BEIS) biosensor by electric field-focusing in microwells

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 51 δευτερόλεπτα

[image: S09565663.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): Kyeong.-Sik. Shin, Jae Hoon Ji, Kyo Seon Hwang, Seong Chan Jun, Ji Yoon Kang This paper reports a novel electrochemical impedance spectroscopy (EIS) biosensors that uses magnetic beads trapped in a microwell array to improve the sensitivity of conventional bead-based EIS (BEIS) biosensors. Unloading the previously measured beads by removing the magnetic bar enables the BEIS sensor to be used repeatedly by reloading it with new beads. Despite its recyclability, the s... περισσότερα »

Portable, one-step, and rapid GMR biosensor platform with smartphone interface

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 51 δευτερόλεπτα

[image: S09565663.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): Joohong Choi, Adi Wijaya Gani, Daniel J.B. Bechstein, Jung-Rok Lee, Paul J. Utz, Shan X. Wang Quantitative immunoassay tests in clinical laboratories require trained technicians, take hours to complete with multiple steps, and the instruments used are generally immobile–patient samples have to be sent in to the labs for analysis. This prevents quantitative immunoassay tests to be performed outside laboratory settings. A portable, quantitative immunoassay device will... περισσότερα »

Overcoming the Interface Losses in Planar Heterojunction Perovskite-Based Solar Cells

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 51 δευτερόλεπτα

[image: Thumbnail image of graphical abstract] *A scalable, hysteresis free and planar architecture perovskite solar cells* is presented, employing a flame spray synthesized low-temperature processed NiO (LT-NiO) as hole-transporting layer yielding efficiencies close to 18%. Importantly, it is found that LT-NiO boosts the limits of open circuit voltages towards an impressive non-radiative voltage loss of 0.226 V only, whereas PEDOT:PSS suffers from significant large non-radiative recombination losses. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1WHujJn ... περισσότερα »

Difficult septal deviation cases

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

: is it open or closed technique? via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 29 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Sultan Şevik Eliçora, Duygu Erdem, Hüseyin Işık, Murat Damar, Aykut Erdem Dinç IntroductionAim of this study is to compare the functional aspects of open technique (OTS) and endonasal septoplasty (ENS) in “difficult septal deviation cases”.Methods60 patients who have nasal obstruction because of S-shaped deformities, multiple deformities, high deviations etc. were included ... περισσότερα »

Assessment of hearing threshold in adults with hearing loss

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

using an automated system of cortical auditory evoked potential detection via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 29 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Alessandra Spada Durante, Margarita Bernal Wieselberg, Nayara Costa, Sheila Carvalho, Beatriz Pucci, Nicolly Gudayol, Kátia de Almeida IntroductionThe use of hearing aids by individuals with hearing loss brings a better quality of life. Access to and benefit from these devices may be compromised in patients who present difficulties or ... περισσότερα »

Ossicular chain reconstruction with resin cement

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Feasibility of via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 29 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Fernando de Andrade Quintanilha Ribeiro, Yumi Tamaoki, Gabriel Wynne Cabral IntroductionDisjunction of ossicular chain is a common finding in middle ear chronic disease. In addition to ossicular interposition, various materials have been used reconstruction, such as ceramic prostheses, polyethylene, and titanium.ObjectiveBecause of the high cost of the available options, the authors proposed...περισσότερα »

The role of facial canal diameter in pathogenesis and grade of Bell's palsy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

: a study by high resolution computed tomography via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 29 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Onur Celik, Gorkem Eskiizmir, Burak Ulkumen, Gokce Tanyeri Toker, Yuksel Pabuscu IntroductionThe exact etiology of Bell's palsy still remains obscure. The only authenticated finding is the inflammation and edema of the facial nerve (FN) leading entrapment inside the facial canal.ObjectiveTo identify if there is any relationship between the grade of Bell's pals...περισσότερα »

Implantierbare Knochenleitungs- und aktive Mittelohr-Hörsysteme

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Implantierbare Knochenleitungs- und aktive Mittelohr-Hörsysteme: Laryngo-Rhino-Otol 2016; 95: 352-363 DOI: 10.1055/s-0042-104946 Ein Großteil der schwerhörigen Patienten kann mit konventionellen Hörgeräten abhängig von Schweregrad und Ursache der Hörstörung gut und zufriedenstellend versorgt werden. Für manche Patienten ist eine Hörgeräteversorgung trotz audiologisch eindeutig vorliegender Kriterien aus unterschiedlichen Gründen (anatomisch, entzündlich, u. a.) nicht möglich oder führt nicht zu einem zufriedenstellenden Hörergebnis. Für diese Patientengruppe stehen verschiedene tei...περισσότερα »

Aktueller Stand Salvage-chirurgischer Therapiekonzepte bei Rezidivtumoren des Larynx und Pharynx

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Aktueller Stand Salvage-chirurgischer Therapiekonzepte bei Rezidivtumoren des Larynx und Pharynx: Laryngo-Rhino-Otol 2016; 95: 313-319 DOI: 10.1055/s-0042-103591 Die therapeutischen Konzepte bei Kopf-Hals-Malignomen haben in den letzten 20 Jahren einen erheblichen Wandel erfahren, der mit einer zunehmenden Bedeutung nicht-chirurgischer Therapieverfahren einhergeht. Auch unter den Organerhaltungsprotokollen bzw. nach primärer Radiochemotherapie kommt es jedoch in erheblichem Umfang zum Auftreten von Tumorrezidiven. In dieser Situation stellt die Salvage- bzw. Rettungschirurgie im Ko... περισσότερα »

Interrogation of cancer hotspot mutations in 50 tumour suppressor genes and oncogenes in calcifying cystic odontogenic tumour

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Interrogation of cancer hotspot mutations in 50 tumour suppressor genes and oncogenes in calcifying cystic odontogenic tumour: [image: gr1.sml] Calcifying cystic odontogenic tumour (CCOT) is a cystic encapsulated tumour lined by odontogenic epithelium similar to the ameloblastoma’s epithelium, containing ghost cells that may calcify [1,2]. CCOT is locally destructive, which contrasts with the aggressive behavior of the solid variant classified as a separate entity, the dentinogenic ghost cell tumour [1,3].

Angiolymphoid Hyperplasia With Eosinophilia Within a Vascular Malformation: Case Report and Review of the Literature

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Case Report and Review of the Literature: Objectives: Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign microvascular proliferation tumor. The etiology of ALHE is unknown, though some hypothesize it occurs in reaction to focal trauma. This study presents a case of AHLE within a vascular malformation, its treatment, and a review of the literature. Methods: A retrospective case report was performed with a 4-year follow-up. Medical records including clinic notes, radiography, operative reports, pathology, and long-term follow-up were reviewed. Results: Radiologic... περισσότερα »

Gustatory Dysfunction and Decreased Number of Fungiform Taste Buds in Patients With Chronic Otitis Media With Cholesteatoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Gustatory Dysfunction and Decreased Number of Fungiform Taste Buds in Patients With Chronic Otitis Media With Cholesteatoma: Objective: To compare the number of fungiform taste buds among patients with chronic otitis media (COM), those with pars flaccida retraction type cholesteatoma, and those with pars tensa retraction type cholesteatoma in combination with gustatory function. Methods: Thirty-seven patients with COM, 22 patients with pars flaccida retraction type cholesteatoma, and 17 patients with pars tensa retraction type cholesteatoma were included. An average of 10 fungiform...περισσότερα »

Laryngeal adenocarcinoma not otherwise specified: A population-based perspective

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Laryngeal adenocarcinoma not otherwise specified: A population-based perspective: Objectives/Hypothesis Laryngeal adenocarcinoma not otherwise specified (LAdC NOS) is a category to which variants of minor salivary gland tumors of the larynx that do not fit other well-characterized histological subtypes are assigned. Its rare nature and inconsistency in available reports has hindered the investigation and further understanding of this malignancy. In this study, a national population-based resource was used to evaluate the epidemiology and survival of this rare entity. Study Des... περισσότερα »

Utility of brain MRI in children with sleep-disordered breathing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Utility of brain MRI in children with sleep-disordered breathing: Objectives/Hypothesis To investigate the utility of a brain magnetic resonance imaging (MRI) in children with sleep-disordered breathing (SDB), classified as isolated obstructive sleep apnea (OSA) in the absence of adenotonsillar hypertrophy, persistent OSA following adenotonsillectomy, isolated central sleep apnea (CSA) of unclear etiology, OSA with coexisting CSA of unclear etiology, or unexplained nocturnal hypoventilation (NH). Study Design Retrospective chart review of polysomnography (PSG) and brain MRI data...περισσότερα »

Head and neck microvascular free flap reconstruction: An analysis of unplanned readmissions

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Head and neck microvascular free flap reconstruction: An analysis of unplanned readmissions: Objectives/Hypothesis Unplanned readmissions within 30 days of surgery represent a significant marker for healthcare quality. Small institutional studies have described rates of readmission for patients undergoing head and neck free flap reconstruction. However, large, multi-institutional analyses have not previously been described. Study Design Retrospective study of cases from the American College of Surgeons National Surgical Quality Improvement Program database. Methods Patients who...περισσότερα »

Validation of a self-administered audiometry application: An equivalence study

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Validation of a self-administered audiometry application: An equivalence study: Objectives/Hypothesis To compare hearing measurements made at home using self-administered audiometric software against audiological tests performed on the same subjects in a clinical setting Study Design Prospective, crossover equivalence study Methods In experiment 1, adults with varying degrees of hearing loss (N = 19) performed air-conduction audiometry, frequency discrimination, and speech recognition in noise testing twice at home with an automated tablet application and twice in sound-treated... περισσότερα »

Nasal obstruction has a limited impact on sleep quality and quality of life in patients with chronic rhinosinusitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Nasal obstruction has a limited impact on sleep quality and quality of life in patients with chronic rhinosinusitis: Objectives/Hypothesis Nasal obstruction is a cardinal symptom in diagnosing chronic rhinosinusitis (CRS), and decreased sleep quality (SQ) and quality of life (QOL) are commonly reported in CRS. It is, however, unclear what role nasal obstruction severity plays in this decreased SQ and QOL. Using validated instruments, we evaluated the relationship between nasal obstruction severity, SQ, and QOL. Study Design Prospective case series. Methods Patients with CRS re...περισσότερα »

Outcomes in thyroid surgery are affected by racial, economic, and heathcare system demographics

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Outcomes in thyroid surgery are affected by racial, economic, and heathcare system demographics: Objectives/Hypothesis Disparities in economic and social parameters have been identified as underlying factors that influence diseases outcomes. We aim to examine the influence of community-specific measures on outcomes related to thyroid surgery. Study Design A cross-sectional study utilizing the State Inpatient databases and State Ambulatory Surgery and Services databases, 2010 to 2011. Those databases were merged with the County Health Ranking database. Methods The study populati...περισσότερα »

Prevalence of peri-implant disease on platform switching implants: a cross-sectional pilot study.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

[image: http:--www.scielo.br-img-scielo.gif] Braz Oral Res. 2016;30 Authors: Duque AD, Aristizabal AG, Londoño S, Castro L, Alvarez LG Abstract The objective of this study was to assess the prevalence of mucositis and peri-implantitis associated with the use of two types of implants-conventional versus platform switching after one year of loading. A longitudinal study of 64 implants in 25 patients was performed. Clinical variables, such as clinical pocket depth and bleeding upon probing, plaque, mobility, gingival recession, clinical attachment loss, and radiographic bone loss, ... περισσότερα »

Stevens-Johnson Syndrome Developing during Chemoradiotherapy for Maxillary Sinus Cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

[A Case of Authors: Yoshifuku K, Nishimoto K, Matsuzaki T, Matsushita S Abstract Herein, we report a case of drug-induced Stevens Johnson syndrome. (SJS). A 56-year old female visited our hospital complaining of right cheek pain. Local examination revealed that the right ostium of the maxillary sinus was open and that the maxillary sinus mucosa was invaded by tumor. Biopsy revealed a histopathological diagnosis of squamous cell carcinoma. We therefore diagnosed the patient as a case of maxillary sinus carcinoma (T3N0M0) based on the CT, MRI and FDG-PET findings. During chemoradiot...περισσότερα »

Cryotherapy and chlorhexidine to oral nutrition transition time in chemotherapy-induced oral mucositis.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Comparison of efficacy of Eur J Cancer Care (Engl). 2016 May 1; Authors: Erden Y, Ipekcoban G Abstract The aim of this study was to compare the efficacy of cryotherapy and chlorhexidine to oral nutrition transition time in chemotherapy-induced oral mucositis. This randomised controlled trial with random assignments to the experimental and control groups was conducted with cancer patients. Study data were collected from 90 cancer patients. The first experimental group (n = 30) received chlorhexidine mouthwash, the second experimental group (n = 30) received oral cryotherapy and the...περισσότερα »

Induction chemotherapy with dose-modified docetaxel, cisplatin, and 5-fluorouracil

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

in Asian patients with borderline resectable or unresectable head and neck cancer.: J Formos Med Assoc. 2016 Apr 25; Authors: Wang HM, Lin CY, Hsieh CH, Hsu CL, Fan KH, Chang JT, Huang SF, Kang CJ, Liao CT, Ng SH, Yen TC Abstract BACKGROUND: Significant ethnic differences in susceptibility to the effects of chemotherapy exist. Here, we retrospectively analyzed the safety and efficacy of induction chemotherapy (ICT) with dose-modified docetaxel, cisplatin, and 5-fluorouracil (TPF) in Asian patients with borderline resectable or unresectable head and neck squamous cell carcinoma (H...περισσότερα »

Chemoradiation Plus Pembrolizumab for Locally Advanced Laryngeal Squamous Cell Carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

A Study of *Condition*: Head and Neck Cancer *Interventions*: Drug: Pembrolizumab; Radiation: Radiation Therapy; Drug: Cisplatin *Sponsors*: Nooshin Hashemi-Sadraei; Merck Sharp & Dohme Corp. ArmsAssigned Interventions Experimental: Pembrolizumab Pembrolizumab every 3 weeks in combination with 7 weeks of radiation therapy and every 3 week cisplatin Drug: Pembrolizumab 200mg every 3 weeks starting 3 weeks prior to chemoradiotherapy. Maximum of 4 doses Other Name: Keytruda Radiation: Radiation Therapy 70 Gy in 35 fractions over 7 weeks Drug: Cisplatin 100 mg/m2 every 3 w... περισσότερα »

Prognostic significance of metabolic tumor volume in patients with piriform sinus carcinoma treated by radiotherapy with or without concurrent chemotherapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Prognostic significance of metabolic tumor volume in patients with piriform sinus carcinoma treated by radiotherapy with or without concurrent chemotherapy: Abstract Background The purpose of this study was to elucidate the prognostic significance of the pretreatment metabolic tumor volume (MTV) in patients with piriform sinus carcinoma treated by radiation-based therapy. Methods This retrospective study included 100 patients with piriform sinus carcinomas who had received treatment by radiation-based therapy. The MTV values were obtained from pretreatment positron emission tomograp...περισσότερα »

Nasoseptal flap for reconstruction after robotic radical tonsillectomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Nasoseptal flap for reconstruction after robotic radical tonsillectomy: Abstract Background The nasoseptal flap has revolutionized reconstruction of ventral skull base defects. The past decade is also noticeable by the evolution of transoral robotic surgery (TORS). Reconstruction of the oropharyngeal defect is challenging. Good reconstructive options with less cicatricial retraction are desirable and still lacking in the literature. Methods Cadaver dissection and illustrative case are used to show the feasibility of harvesting a nasoseptal flap to reconstruct oropharyngeal defect aft... περισσότερα »

Endoscopy versus imaging: Analysis of surveillance methods in sinonasal malignancy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Endoscopy versus imaging: Analysis of surveillance methods in sinonasal malignancy: Abstract Background The purpose of this study was to assess the utility of imaging and endoscopy in posttreatment surveillance of sinonasal malignancies. Methods We conducted a retrospective analysis of primary sinonasal malignancies diagnosed between 2000 and 2014. Posttreatment surveillance included nasal endoscopy and imaging (MRI, CT, and positron emission tomography [PET]/CT). Positive predictive value (PPV), negative predictive value (NPV), specificity, and sensitivity were calculated for each ...περισσότερα »

Endoscopic-assisted transoral-transpharyngeal approach to parapharyngeal space and infratemporal fossa: focus on feasibility and lessons learned

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

Endoscopic-assisted transoral-transpharyngeal approach to parapharyngeal space and infratemporal fossa: focus on feasibility and lessons learned: AbstractThe parapharyngeal space (PPS) is a challenging anatomical region, rich in vascular and nervous vital structures. Surgery is considered the treatment of choice for the majority of PPS lesions. Herein, we present a retrospective evaluation on ten patients with various types of lesions of the parapharyngeal and infratemporal fossa (ITF) regions operated on via an endoscopic-assisted transoral-transpharyngeal approach (EATTA), focusin... περισσότερα »

If cytology of Warthin tumor is accurate, can management be conservative?

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα

If cytology of Warthin tumor is accurate, can management be conservative?: Alexander C. Vlantis, FCS(SA)ORL; Siu Kwan Ng, FRCSEd; Chi Keung Mak, MRCS(Ed); Jackie M. Cheung, MBChB; Amy B. Chan, FHKC Path; C. Andrew van Hasselt, MMed(Otol) AbstractWe conducted a retrospective study to assess the accuracy of fine-needle aspiration cytology (FNAC) in the diagnosis of Warthin tumor and to evaluate the subsequent risk of conservative nonsurgical management. We reviewed the records of 75 patients (76 tumors) with a parotid mass that had been diagnosed as a Warthin tumor by FNAC. This patie... περισσότερα »