A second family with CATSHL syndrome: Confirmatory report of another unique FGFR3 syndrome.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 4 δευτερόλεπτα
*A second family with CATSHL syndrome: Confirmatory report of another unique FGFR3 syndrome.* Am J Med Genet A. 2016 May 3; Authors: Escobar LF, Tucker M, Bamshad M Abstract Here we describe the second reported family with the CATSHL syndrome, a condition resulting from a unique mutation in the fibroblast growth factor receptor 3 (FGFR3) gene. Our family confirms the consistent and unique phenotype of this condition, and the specificity of the mutation in FGFR3. The CATSHL syndrome appears to be an autosomal dominant disorder with full penetrance. © 2016 Wiley Periodicals, Inc. ...περισσότερα »
Barriers to early cochlear implantation.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 4 δευτερόλεπτα
*Barriers to early cochlear implantation.* Int J Audiol. 2016 May 3;:1-13 Authors: Dettman S, Choo D, Dowell R Abstract OBJECTIVE: Identify variables associated with paediatric access to cochlear implants (CIs). DESIGN: Part 1. Trends over time for age at CI surgery (N = 802) and age at hearing aid (HA) fitting (n = 487) were examined with regard to periods before, during, and after newborn hearing screening (NHS). Part 2. Demographic factors were explored for 417 children implanted under 3 years of age. Part 3. Pre-implant steps for the first 20 children to receive CIs under 12 ... περισσότερα »
A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 4 δευτερόλεπτα
[image: http:--http://ift.tt/1Iu32Gt] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment.* PLoS Genet. 2015 Jul;11(7):e1005386 Authors: Nyegaard M, Rendtorff ND, Nielsen MS, Corydon TJ, Demontis D, Starnawska A, Hedemand A, Buniello A, Niola F, Overgaard MT, Leal SM, Ahmad W, Wikman FP, Petersen KB, Crüger DG, Oostrik J, Kremer H, Tommerup N, Frödin M, Steel KP, Tranebjærg L, Børglum AD Abstract Nonsyndromic hearing impairment (NSHI) is a hig... περισσότερα »
Long-term follow-up of early cleft maxillary distraction
Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 8 δευτερόλεπτα
Abstract Background Most of cleft lip and palate patients have the esthetic and functional problems of midfacial deficiencies due to innate developmental tendency and scar tissues from repeated operations. In these cases, maxillary protraction is required for the harmonious facial esthetics and functional occlusion. Case presentation A 7-year old boy had been diagnosed as severe maxillary constriction due to unilateral complete cleft lip and palate. The author tried to correct the secondary deformity by early distraction osteogenesis with the aim of avoiding marked psychological ... περισσότερα »
Sinonasal Tract Inflammation as a Precursor to Nasopharyngeal Carcinoma: A Systematic Review and Meta-Analysis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Sinonasal Tract Inflammation as a Precursor to Nasopharyngeal Carcinoma: A Systematic Review and Meta-Analysis: Objective Chronic inflammation has been described as a precursor to the development of malignancy in several disease states. However, the relationship of sinonasal tract inflammation to nasopharyngeal carcinoma (NPC) remains poorly defined. Data Sources Systematic review of primary studies identified through PubMed, EMBASE, MEDLINE, and Cochrane. Methods Review Systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic R... περισσότερα »
Modeled Analysis of Entrance of Colloid Suspensions into the Middle Ear Cavity
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Modeled Analysis of Entrance of Colloid Suspensions into the Middle Ear Cavity: Otic suspensions have a positive effect on the duration of otorrhea in children with a tympanostomy tube. It is still questionable how eardrops reach the middle ear. We hypothesized that otic suspensions do not pass the tympanostomy tube if the middle ear is dry but pass by diffusion when wet. The median concentration of Evans blue (colorant) in the middle ear was <15.6 mg/mL (lower limit of quantification) when diffusion was impossible but 45.3 µg/mL when diffusion was possible (*P* = .01). When the ou... περισσότερα »
Otolaryngology -- Head and Neck Surgery RSS feed -- OnlineFirst Articles
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Corrigendum 10.1177/0194599815591809 Videofluoroscopic Swallow Examination Does Not Accurately Detect Cricopharyngeal Radiation Strictures Videofluoroscopy is the standard technique to evaluate dysphagia following radiotherapy for head and neck cancer (HNC). The accuracy of radiography in detecting strictures at the pharyngoesophageal junction is unknown. Our aim was to determine the diagnostic accuracy of videofluoroscopy in detecting strictures at the pharyngoesophageal junction prior to endoscopic dilatation in a consecutive series of HNC survivors with dysphagia. Presence of a s... περισσότερα »
Otolaryngology -- Head and Neck Surgery current issue
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Highlights from the Current Issue: May 2016 Reoperation following Adult Tonsillectomy: Review of the American College of Surgeons National Surgical Quality Improvement Program ObjectiveTonsillectomy remains a common procedure in adults; however, there are few population-level data evaluating risk factors for reoperation.Study DesignRetrospective review of national database.SettingAmerican College of Surgeons National Surgical Quality Improvement Program (ACS-NSQIP), 2005-2013.Subjects and MethodsThe ACS-NSQIP was queried for patients undergoing tonsillectomy ± adenoidectomy as their... περισσότερα »
Paravertebral Nerve Block for Donor Site Pain in Stage I Microtia Reconstruction: A Pilot Study
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
A Pilot Study: Acute Interventional Perioperative Pain Service consultants have routinely placed paravertebral nerve block (PVB) catheters for the continuous release of ropivacaine following stage I microtia reconstruction with costal cartilage graft at our institution since 2010. A retrospective chart review from July 2006 was performed to compare the length of hospital stay, median pain score (0-10 scale), and opioid use of patients receiving PVB with those of historical controls. Statistical analysis included *t*, Mann-Whitney *U*, and Fisher’s exact tests. A total of 15 stage ... περισσότερα »
Sino-Nasal Outcome Test-22
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Translation, Cross-cultural Adaptation, and Validation in Hebrew-Speaking Patients: Objective To perform the translation, cross-cultural adaptation, and validation of the Sino-Nasal Outcome Test–22 (SNOT-22) questionnaire to the Hebrew language. Study Design and Setting A single-center prospective cross-sectional study. Subjects and Methods Seventy-three chronic rhinosinusitis (CRS) patients and 73 patients without sinonasal disease filled the Hebrew version of the SNOT-22 questionnaire. Fifty-one CRS patients underwent endoscopic sinus surgery, out of which 28 filled a postoper...περισσότερα »
Obstructive Sleep Apnea
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Differences between Normal-Weight, Overweight, Obese, and Morbidly Obese Children: Introduction The severity of obstructive sleep apnea in children determines perioperative management and is an indication for postoperative polysomnography. The relationship between increasing weight and sleep apnea severity in children remains unclear. Objectives To compare demographic, clinical, and polysomnography parameters in normal-weight, overweight, obese, and morbidly obese children, as well as identify demographic factors that predict sleep apnea severity. Study Design Case series with c... περισσότερα »
Variation in Delivery of Sinus Surgery in the Medicaid Population across Ethnicities
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Variation in Delivery of Sinus Surgery in the Medicaid Population across Ethnicities: Objective To evaluate differences in sinus surgery rates in the US Medicaid population by ethnicities. Study Design Retrospective administrative database analysis. Setting US-based outpatient settings. Methods All patients from the MarketScan Medicaid database with endoscopic sinus surgery from 2009 to 2013 were stratified by ethnicity, age (5-year increments, as per US Census), and sex. Crude rates of endoscopic sinus surgery per age group and sex were compiled for all patients and each ethni...περισσότερα »
Efficacy of Upper Airway Stimulation on Collapse Patterns Observed during Drug-Induced Sedation Endoscopy
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Efficacy of Upper Airway Stimulation on Collapse Patterns Observed during Drug-Induced Sedation Endoscopy: Objective To describe upper airway collapse patterns observed on drug-induced sedation endoscopy (DISE) during screening for a clinical trial and to evaluate the impact of collapse patterns found on preoperative DISE on response rates to upper airway stimulation (UAS) therapy. Study Design Retrospective review of an ongoing prospective multi-institutional cohort study. Setting Twenty-two participating institutions of the STAR trial. Subjects and Method In total, 222 subject... περισσότερα »
Acute Rhinosinusitis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Prescription Patterns in a Real-World Setting: Objective Understand real-world prescription patterns for patients presenting with a first diagnosis of ARS and evaluate adherence to published medical guidelines. Study Design Retrospective administrative database analysis. Setting US-based outpatient settings. Methods From a US claims database (MarketScan), 99,033 patients were identified with acute rhinosinusitis (ARS) in 2012 ("index"), with a complete medical and prescription history for 12 months preindex and 18 months postindex and no diagnoses of asthma or chronic rhinosinus...περισσότερα »
Orbital Decompression in the Endoscopic Age
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
The Modified Inferomedial Orbital Strut: Objective Postoperative diplopia occurs in up to 45% of patients following orbital decompression for exophthalmos associated with Graves’ orbitopathy. We sought to describe outcomes of our balanced orbital decompression strategy that includes the preservation of a modified inferomedial orbital strut (mIOS). Study Design Case series with chart review. Setting Academic medical center. Subjects and Methods A total of 115 consecutive orbital decompressions were performed on 73 patients (42 bilateral) with Graves’ orbitopathy. All patients und... περισσότερα »
Die Entwicklung der ersten OP-Mikroskope von Zeiss Jena und Oberkochen bis zur Serienfertigung
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Die Entwicklung der ersten OP-Mikroskope von Zeiss Jena und Oberkochen bis zur Serienfertigung: Laryngo-Rhino-Otol DOI: 10.1055/s-0042-104416 Einleitung: Die Entstehungsgeschichte des ersten Operationsmikroskops von Zeiss wird wegen ihres parallelen Verlaufs bei Zeiss Jena und Zeiss Oberkochen häufig unübersichtlich, nicht gründlich und zum Teil widersprüchlich dargestellt. Methodik: Für die Recherche standen das Carl Zeiss Archiv und das Optischen Museum in Jena, die Lebenserinnerungen von Prof. Dr. Rosemarie Albrecht und einschlägige Veröffentlichungen zur Verfügung. Ergebnisse... περισσότερα »
Evidenz und Evidenzlücken – eine thematische Einführung
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Evidenz und Evidenzlücken – eine thematische Einführung: Laryngo-Rhino-Otol 2016; 95: S6-S12 DOI: 10.1055/s-0041-108944 Hintergrund: Ärztliches Handeln erfordert die Einbeziehung vorhandener Evidenz in die Entscheidungsfindung, um vor dem Hintergrund der eigenen Expertise die für einen konkreten Patienten bestmögliche Diagnose oder Therapiemaßnahme anzuwenden oder valide Prognoseaussagen treffen zu können. Evidenzbasis sind klinische Studien, deren Ergebnisse idealerweise in systematischen Übersichtsarbeiten zusammengetragen, bewertet, zusammengefasst und zur Verfügung gestellt wer... περισσότερα »
Zufriedenheit nach Stimmerhöhung bei Transsexualität – Entwicklung eines Therapiealgorithmus
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Zufriedenheit nach Stimmerhöhung bei Transsexualität – Entwicklung eines Therapiealgorithmus: Laryngo-Rhino-Otol DOI: 10.1055/s-0042-103590 Hintergrund: Im Rahmen der Transition von Mann zu Frau ist die Stimmtherapie ein wichtiger Bestandteil einer ganzheitlichen Therapie. Die Therapie besteht aus konservativ logopädischen und operativen Ansätzen, es existieren allerdings keine einheitlichen Standards. Neben der Sprechstimmlage wird die Geschlechtswahrnehmung von vielen Faktoren wie Formantfrequenzen, Intonation, Prosodie und Verhaltensmerkmalen beeinflusst. Material und Methoden... περισσότερα »
Evidenz und Evidenzlücken für medikamentös zu behandelnde, nicht-tumoröse Erkrankungen im Gebiet der HNO-Heilkunde
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Evidenz und Evidenzlücken für medikamentös zu behandelnde, nicht-tumoröse Erkrankungen im Gebiet der HNO-Heilkunde: Laryngo-Rhino-Otol 2016; 95: S217-S232 DOI: 10.1055/s-0041-108940 In unserem Fach der HNO-Heilkunde behandeln wir zahlreiche Krankheiten, die leider aufgrund mangelnder Studienlage nicht immer evidenzbasiert sind.Während für die spezifische Immuntherapie der allergischen Rhinitis und bedingt auch für das durch Angiotensin-Converting-Enzyme-Hemmer induzierte Angioödem ausreichend hochwertige Studien zur Verfügung stehen, ist für den Morbus Menière oder für die medikam... περισσότερα »
Tonsillektomie bei PANDAS?
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Tonsillektomie bei PANDAS?: Laryngo-Rhino-Otol 2016; 95: S110-S115 DOI: 10.1055/s-0041-109592 Hintergrund: Beim PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Assocciated with Streptoccocal Infections) handelt es sich um ein Krankheitsbild, bei dem Zwangs- und Ticstörungen auf eine Streptokokken-Infektion zurückgeführt werden. Anhand einer Literaturrecherche sollte geklärt werden, inwieweit die Tonsillektomie (TE) als therapeutische Maßnahme zu empfehlen ist. Methoden: Bei PubMed wurde mit den Schlagworten tonsillectomy und PANDAS, OCD, compulsive, pediatric autoimmune, C... περισσότερα »
Evidenz- und Evidenzlücken der Tinnitustherapie
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Evidenz- und Evidenzlücken der Tinnitustherapie: Laryngo-Rhino-Otol 2016; 95: S155-S191 DOI: 10.1055/s-0041-108946 Für die Behandlung von Ohrgeräuschen werden eine schier unübersichtliche Vielzahl von Verfahren erprobt und v. a. verkauft, leider nicht immer sachgerecht und evidenzbasiert untersucht. Eine kausale, den Tinnitus abschaltende Therapie gibt es nach wie vor nicht, ja eigentlich kann es sie nicht geben, hat man die verschiedenen Entstehungsmechanismen verstanden. Dennoch oder deshalb kehren im Verlauf der letzten Jahrzehnte wellen- und modeartig medizinische Interventione...περισσότερα »
Tonsillektomie: offizielle Zahlen und Trends
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
in Deutschland: Laryngo-Rhino-Otol 2016; 95: S88-S109 DOI: 10.1055/s-0041-109594 Hintergrund: Über eine unterschiedliche Tonsillektomierate pro Einwohnerzahl im regionalen und zeitlichen Vergleich wird in der internationalen Literatur immer wieder berichtet. Ziel der vorliegenden Studie war es, die Häufigkeit stationärer Behandlungen von chronischer Tonsillitis, Tonsillenhyperplasie und adenotonsillärer Hyperplasie für Deutschland mit über 80 Mio Einwohnern zu ermitteln. Außerdem sollte die Rate an Tonsillektomien, Abszesstonsillektomien, transoralen Inzisionsdrainagen von Perito... περισσότερα »
Evidenz und Evidenzlücken bei der Behandlung der behinderten Nasenatmung und der Rhinosinusitis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Evidenz und Evidenzlücken bei der Behandlung der behinderten Nasenatmung und der Rhinosinusitis: Laryngo-Rhino-Otol 2016; 95: S116-S135 DOI: 10.1055/s-0041-109059 Therapieverfahren in der Hals-Nasen-Ohrenheilkunde beruhen heute auf klinischer Erfahrung, chirurgischer Ausbildung und wissenschaftlicher Evidenz. Seit einigen Jahren gewinnt jedoch der Aspekt der evidenzbasierten Behandlung u. a. wegen des Potenzials zur Verbesserung von individuellen Behandlungen, aber auch aufgrund der wirtschaftlichen Rahmenbedingungen zunehmend an Bedeutung. Gleichzeitig ist es in der klinischen Pra... περισσότερα »
Evidenz basierte Indikationen der Tonsillektomie
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Evidenz basierte Indikationen der Tonsillektomie: Laryngo-Rhino-Otol 2016; 95: S38-S87 DOI: 10.1055/s-0041-109590 Hintergrund: Die erste wissenschaftlich hochwertige Studie zur Indikationsstellung der Tonsillektomie wurde von Jack L. Paradise geleitet und 1984 (TE) publiziert. Ziel dieser systematischen Literaturrecherche war es, anhand einer standardisierten Suchstrategie Publikationen zusammenzustellen, die sich nach 1984 mit den Operationsindikationen der TE auseinandersetzten. Methoden: berücksichtigt wurden ausschließlich systematische Reviews, Metaanalysen, Leitlinien sowie ... περισσότερα »
Evidenz und Evidenzlücken zur Chirurgie des Larynxkarzinoms
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Evidenz und Evidenzlücken zur Chirurgie des Larynxkarzinoms: Laryngo-Rhino-Otol 2016; 95: S192-S216 DOI: 10.1055/s-0041-108962 Die operative Therapie von Larynxkarzinomen ist seit Jahrzehnten etabliert. Neben der Laryngektomie, die erstmals 1873 durchgeführt wurde, haben sich eine Vielzahl larynxerhaltender Operationstechniken, wie verschiedene offene Teilresektionen, die transorale Laserchirurgie und zuletzt die transorale Roboterchirurgie, entwickelt. Die am häufigsten angewendeten Studienformen in Studien zur Chirurgie des Larynxkarzinoms sind retrospektive Analysen von Fallseri...περισσότερα »
Qualitative Umfrage zur Identifizierung von Evidenzlücken in der HNO-Heilkunde
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Qualitative Umfrage zur Identifizierung von Evidenzlücken in der HNO-Heilkunde: Laryngo-Rhino-Otol 2016; 95: S13-S37 DOI: 10.1055/s-0041-108949 Einleitung: Der Zuwachs des Wissens in der HNO-Heilkunde übersteigt, wie in den anderen Disziplinen auch, seit langem die individuellen Möglichkeiten, dieses Wissen adäquat aufzunehmen und einen entsprechenden Überblick zu behalten. Somit können tatsächliche oder vermeintliche Wissenslücken entstehen, die der Weiterentwicklung des Faches und einer evidenzbasierten Behandlung von Patienten entgegenstehen. Zudem gibt es in Kliniken und Praxe... περισσότερα »
Implementierung von Studienergebnissen in Leitlinien und deren Umsetzung in die Klinik
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Implementierung von Studienergebnissen in Leitlinien und deren Umsetzung in die Klinik: Laryngo-Rhino-Otol 2016; 95: S233-S251 DOI: 10.1055/s-0041-108961 Leitlinien wurden in den neunziger Jahren des letzten Jahrhunderts in die klinische und praktische Hals-Nasen-Ohren-Heilkunde eingeführt und seither kontinuierlich weiterentwickelt. Aktuell liegen 20 Leitlinien der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie vor. An 34 weiteren Leitlinien fand eine Mitwirkung statt. Durch konkrete Vorgaben der Arbeitsgemeinschaft wissenschaftlicher medizinischer ...περισσότερα »
Evidenz und Evidenzlücken zur Behandlung der gestörten Mittelohrbelüftung sowie der Otitis media
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Evidenz und Evidenzlücken zur Behandlung der gestörten Mittelohrbelüftung sowie der Otitis media: Laryngo-Rhino-Otol 2016; 95: S136-S154 DOI: 10.1055/s-0041-108952 Evidenzbasierte Medizin bedeutet, im Rahmen einer medizinischen Behandlung eine patientenorientierte Entscheidung auf der Grundlage von empirisch nachgewiesener Wirksamkeit zu treffen. Hierzu existieren Klassifizierungen, in welchen nach definierten Vorgaben Studien und damit Therapieoptionen hinsichtlich ihrer Evidenz eingeteilt werden können.Die Tuba eustachii verbindet den Nasopharynx mit dem Mittelohr. Ihre Hauptaufg... περισσότερα »
Characteristics of Antithyroid Drug–Induced Agranulocytosis in Patients with Hyperthyroidism
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
A Retrospective Analysis of 114 Cases in a Single Institution in China Involving 9690 Patients Referred for Radioiodine Treatment Over 15 Years: Thyroid May 2016, Vol. 26, No. 5: 627-633. Author information Jun Yang,1 Yang-Jun Zhu,1 Ji-Jun Zhong,2 Jun Zhang,1 Wan-Wen Weng,1 Zhen-Feng Liu,3 Qin Xu,1 andMeng-Jie Dong1 1Department of Nuclear Medicine, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou,People's Republic of China. 2Department of Nuclear Medicine, Taizhou Central Hospital, Taizhou, People's Republic of China. 3PET Center, First Affiliated Hosp...περισσότερα »
Predictive Factors for Medical Consultation for Sore Throat in Adults with Recurrent Pharyngotonsillitis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Predictive Factors for Medical Consultation for Sore Throat in Adults with Recurrent Pharyngotonsillitis: Objects. To seek patient- and episode-related factors that associate with medical consultation for acute sore throat because these factors may affect the patient being referred to specialist care and tonsillectomy for recurrent pharyngotonsillitis. Methods. In a secondary analysis of two prior randomised controlled trials, sore throat episodes and medical visits were explored among 156 adult patients referred for tonsillectomy because of recurrent pharyngotonsillitis. Results. T... περισσότερα »
Self-Administered Domiciliary tDCS Treatment for Tinnitus: A Double-Blind Sham-Controlled Study
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Self-Administered Domiciliary tDCS Treatment for Tinnitus: A Double-Blind Sham-Controlled Study: by Petteri Hyvärinen, Antti Mäkitie, Antti A. Aarnisalo Transcranial direct current stimulation (tDCS) has shown potential for providing tinnitus relief, although positive effects have usually been observed only during a short time period after treatment. In recent studies the focus has turned from one-session experiments towards multi-session treatment studies investigating long-term outcomes with double-blinded and sham-controlled study designs. Traditionally, tDCS has been administer... περισσότερα »
Diagnostic Performance of Whole-Body PET/MRI for Detecting Malignancies in Cancer Patients: A Meta-Analysis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Diagnostic Performance of Whole-Body PET/MRI for Detecting Malignancies in Cancer Patients: A Meta-Analysis: by Guohua Shen, Shuang Hu, Bin Liu, Anren Kuang Background As an evolving imaging modality, PET/MRI is preliminarily applied in clinical practice. The aim of this study was to assess the diagnostic performance of PET/MRI for tumor staging in patients with various types of cancer. Methods Relevant articles about PET/MRI for cancer staging were systematically searched in PubMed, EMBASE, EBSCO and the Cochrane Library. Two researchers independently selected studies, extrac... περισσότερα »
The telomere proteins in tumorigenesis and clinical outcomes of oral squamous cell carcinoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
The telomere proteins in tumorigenesis and clinical outcomes of oral squamous cell carcinoma: Telomeres are the distal ends of linear eukaryotic chromosomes and are composed of tandemly repeated DNA elements 5′-TTAGGG-3′. These terminal sequences are capped by specific telomeric proteins and adopt a particular three-dimensional conformation called the T-loop. The formation of this loop is made possible by the existence of a telomeric 3′ single-stranded overhang that invades the double-stranded part of the telomeric DNA. These features prevent the telomeres from being recognized as d...περισσότερα »
Leitlinie: „HNO-spezifische Therapie der obstruktiven Schlafapnoe bei Erwachsenen“ Kurzfassung
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Leitlinie: „HNO-spezifische Therapie der obstruktiven Schlafapnoe bei Erwachsenen“ Kurzfassung: ZusammenfassungDie hier vorgelegte S2e-Leitlinie ist die Aktualisierung der Vorgängerleitlinie „Therapie der obstruktiven Schlafapnoe des Erwachsenen“. Die Aktualisierung erfolgte im Auftrag der Deutschen Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie durch ihre Arbeitsgemeinschaft Schlafmedizin. Die Langversion dieser Leitlinie ist seit dem 5.9.2015 und bis zum 5.9.2020 gültig und seit November 2015 bei der AWMF online (017-069) eingestellt. Nachstehend wird eine ...περισσότερα »
Die vestibulären Kopfgelenke
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Die vestibulären Kopfgelenke: Zusammenfassung EinleitungDer Stellenwert zervikaler Propriozeption für das menschliche Gleichgewichtsempfinden ist bis heute nicht zufriedenstellend geklärt. Ziel der vorliegenden Arbeit war die selektive zervikovestibuläre Provokation mithilfe eines neuen und eigens konstruierten Rumpfexkursionstests (RET). Dieser soll bei fixiertem Kopf und isolierter Rumpfauslenkung eine Beurteilung zervikookulärer Reaktionen und mögliche Effekte von Alterungsprozessen ermöglichen. MethodikDem bisher verwendeten Kopfexkursionstest (KET) wurde der RET statistis...περισσότερα »
Einfluss einer Hörgeräteversorgung auf das Einsilberverstehen und das subjektiv erlebte Alltagshören
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Einfluss einer Hörgeräteversorgung auf das Einsilberverstehen und das subjektiv erlebte Alltagshören: Zusammenfassung HintergrundDie Ton- und Sprachaudiometrie sind wichtige Untersuchungen für die Hörgeräteindikation und die Hörgerätekontrolle. Bei jeder Hörgerätversorgung steht für den Patienten jedoch die Verbesserung des Sprachverstehens im Alltag im Vordergrund. Dies wird durch den Einsatz eines geeigneten Fragebogens evaluiert. Ziel dieser Studie war es, den sprachaudiometrisch nachweisbaren Hörgewinn mittels Freiburger Einsilbertest darzustellen und mit den subjektiven Aussa... περισσότερα »
Inherent Directionality Determines Spatial Release from Masking at the Tympanum
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
in a Vertebrate with Internally Coupled Ears: AbstractIn contrast to humans and other mammals, many animals have internally coupled ears that function as inherently directional pressure-gradient receivers. Two important but unanswered questions are to what extent and how do animals with such ears exploit spatial cues in the perceptual analysis of noisy and complex acoustic scenes? This study of Cope’s gray treefrog (*Hyla chrysoscelis*) investigated how the inherent directionality of internally coupled ears contributes to spatial release from masking. We used laser vibrometry and ...περισσότερα »
Daily Administration of Short-Acting Liothyronine Is Associated with Significant Triiodothyronine Excursions and Fails to Alter Thyroid-Responsive Parameters
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Daily Administration of Short-Acting Liothyronine Is Associated with Significant Triiodothyronine Excursions and Fails to Alter Thyroid-Responsive Parameters: Thyroid , Vol. 0, No. 0. Author information Jacqueline Jonklaas1 and Kenneth D. Burman2 1Division of Endocrinology, Georgetown University Medical Center, Washington, DC. 2Endocrine Section, MedStar Washington Hospital Center, Washington, DC. Address correspondence to: *Jacqueline Jonklaas, MD, PhD* *Division of Endocrinology* *Georgetown University* *Suite 230, Bldg. D* *4000 Reservoir Road, NW* *Washington, DC 20007* *E-mail:*... περισσότερα »
Misdiagnosis of Graves' Disease with Apparent Severe Hyperthyroidism
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
in a Patient Taking Biotin Megadoses Author information Giuseppe Barbesino Thyroid Unit, Massachusetts General Hospital-Harvard Medical School, Boston, Massachusetts. Address correspondence to: *Giuseppe Barbesino, MD* *Thyroid Unit* *Massachusetts General Hospital* *WACC 730S* *55 Fruit Street* *Boston, MA 02114* *E-mail:* gbarbesino@mgh.harvard.edu ABSTRACT *Background:* Accurate immunoassays measuring minute quantities of hormones are the cornerstone of the practice of endocrinology. Despite tremendous advances in this field, novel pitfalls in these tests emerge from time to time. ... περισσότερα »
Safety of Monopolar Electrocautery in Patients With Cochlear Implants
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Safety of Monopolar Electrocautery in Patients With Cochlear Implants: Objective: The outcomes of 2 patients with cochlear implants (CIs) who underwent adenotonsillectomy (AT) with inadvertent use of monopolar cautery are presented. The safety data regarding monopolar cautery use in CI recipients is also reviewed. Study Design: This is a retrospective case series of 2 CI recipients that underwent AT with monopolar cautery and literature review of electrocautery safety in the setting of CI. Results: Two patients with CIs underwent AT with use of monopolar cautery inadvertently by... περισσότερα »
Obstructive sleep apnea and oral language disorders
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Obstructive sleep apnea and oral language disorders via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 28 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Camila de Castro Corrêa, Maria Gabriela Cavalheiro, Silke Anna Theresa Weber, Luciana Paula Maximino IntroductionChildren and adolescents with obstructive sleep apnea (OSA) may have consequences, such as daytime sleepiness and learning, memory, and attention disorders, that may interfere in oral language.ObjectiveTo verify, based on the literature, whether ...περισσότερα »
cVEMP and ABR in the evaluation of vestibular schwannoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Role of cervical vestibular evoked myogenic potentials (cVEMP) and auditory brainstem response (ABR) in the evaluation of vestibular schwannoma via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 28 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Deepa Aniket Valame, Geeta B. Gore IntroductionCervical vestibular evoked myogenic potentials (cVEMP) can assess the integrity of the inferior vestibular nerve thereby promising to be a useful tool in the audiological test battery to diagnose vestibular schwannoma.Ob... περισσότερα »
Temporal processing and long-latency auditory evoked potential
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
in stutterers via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 28 April 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Raquel Prestes, Adriana de Andrade Neves, Renata Beatriz Fernandes Santos, Andrea Tortosa Marangoni, Ana Maria Schiefer, Daniela Gil IntroductionStuttering is a speech fluency disorder, and may be associated with neuroaudiological factors linked to central auditory processing, including changes in auditory processing skills and temporal resolution.ObjectiveTo characterize the temporal processi...περισσότερα »
Pedicled adipofascial infraclavicular flap: Elevation technique and its use for maintaining neck contour and vessel coverage after radical and modified radical neck dissection
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Pedicled adipofascial infraclavicular flap: Elevation technique and its use for maintaining neck contour and vessel coverage after radical and modified radical neck dissection: [image: cover.gif?v=1&s=ed7593daaae1b7c806505d93] ABSTRACT Background The pedicled adipofascial infraclavicular flap (ICF) is based on the anterior perforator of the supraclavicular artery and supplies the fasciocutaneous tissue of the upper chest. This flap may be used to address neck contour defects and vessel coverage after radical and modified radical neck dissections (MRNDs). Methods We described the... περισσότερα »
Retention of Mastoidectomy Skills After Virtual Reality Simulation Training.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Retention of Mastoidectomy Skills After Virtual Reality Simulation Training. : JAMA Otolaryngol Head Neck Surg. 2016 Apr 28; Authors: Andersen SA, Konge L, Cayé-Thomasen P, Sørensen MS Abstract Importance: The ultimate goal of surgical training is consolidated skills with a consistently high performance. However, surgical skills are heterogeneously retained and depend on a variety of factors, including the task, cognitive demands, and organization of practice. Virtual reality (VR) simulation is increasingly being used in surgical skills training, including temporal bone surgery, bu... περισσότερα »
Parathyroid Surgery
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Domestic Travel and Regional Migration for Parathyroid Surgery Among Patients Receiving Care at Academic Medical Centers in the United States, 2012-2014.: JAMA Otolaryngol Head Neck Surg. 2016 Apr 28; Authors: Hinson AM, Hohmann SF, Stack BC Abstract Importance: To improve outcomes after parathyroidectomy, several organizations advocate for selective referral of patients to high-volume academic medical centers with dedicated endocrine surgery programs. The major factors that influence whether patients travel away from their local community and support system for perceived better c... περισσότερα »
Vascular Anomalies
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Education on, Exposure to, and Management of Vascular Anomalies During Otolaryngology Residency and Pediatric Otolaryngology Fellowship.: JAMA Otolaryngol Head Neck Surg. 2016 Apr 28; Authors: Chun R, Jabbour N, Balakrishnan K, Bauman N, Darrow DH, Elluru R, Grimmer JF, Perkins J, Richter G, Shin J Abstract Importance: The field of vascular anomalies presents diverse challenges in diagnosis and management. Although many lesions involve the head and neck, training in vascular anomalies is not universally included in otolaryngology residencies and pediatric otolaryngology (POTO) fell... περισσότερα »
Migration of Nucleocapsids in Vesicular Stomatitis Virus-Infected Cells
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
is Dependent on Both Microtubules and Actin Filaments. J Virol. 2016 Apr 27; Authors: Yacovone SK, Smelser AM, Macosko JC, Holzwarth G, Ornelles DA, Lyles DS Abstract The distribution of vesicular stomatitis virus (VSV) nucleocapsids in the cytoplasm of infected cells was analyzed by scanning confocal fluorescence microscopy using a newly developed quantitative approach called the border-to-border distribution method. Nucleocapsids were located near the cell nucleus at early times postinfection (2 hr), but were redistributed during infection toward the edges of the cell. This red...περισσότερα »
Pre-operative chemoradiotherapy with S-1 as a treatment for locally advanced oral squamous cell carcinoma.
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Clinicopathological evaluation of Oncol Lett. 2016 May;11(5):3369-3376 Authors: Kawano S, Zheng Y, Oobu K, Matsubara R, Goto Y, Chikui T, Yoshitake T, Kiyoshima T, Jinno T, Maruse Y, Mitate E, Kitamura R, Tanaka H, Toyoshima T, Sugiura T, Nakamura S Abstract The administration of pre-operative chemotherapy with S-1 and concurrent radiotherapy at a total dose of 30 Gy was clinicopathologically evaluated as a treatment for locally advanced oral squamous cell carcinoma (OSCC) in the present study. The participants comprised 81 patients with OSCC, consisting of 29 patients with stage...περισσότερα »
The flexible fiber CO2 laser in pediatric transcanal endoscopic middle ear surgery
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Use of via International Journal of Pediatric Otorhinolaryngology Publication date: June 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 85 Author(s): Lukas D. Landegger, Michael S. Cohen We describe 4 pediatric patients (age 6–11 years) who underwent transcanal endoscopic ear surgery (TEES) with the assistance of a flexible fiber CO2 laser over a period of 6 months. Three of these individuals suffered from densely adherent cholesteatoma, where the laser permitted one-handed dissection while preserving endoscopic visualization by limiting bleeding. In the ... περισσότερα »
The osteogenic capacities of mesenchymal stem cells
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Endothelial progenitors enhanced the osteogenic capacities of mesenchymal stem cells in vitro and in a rat alveolar bone defect model via Oral Biology Publication date: August 2016 *Source:*Archives of Oral Biology, Volume 68 Author(s): Yuan Liang, Li Wen, Fengqing Shang, Junjie Wu, Ke Sui, Yin Ding ObjectiveTransplantation of mesenchymal stem cells (MSCs) may promote bone healing. Endothelial progenitor cells (EPCs) may enhance the osteogenic properties of MSCs by improving their microenvironment. We aimed to investigate whether EPCs can enhance the osteogenic properties of MSCs in vi... περισσότερα »
Interventional Treatment for Post-traumatic Headache
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Interventional Treatment for Post-traumatic Headache: AbstractPost-traumatic headache (migraine) is the most common symptom of concussion and traumatic brain injury. An expert opinion-based review along with a literature review (PubMed) was conducted looking at known interventional procedures for post-traumatic headache using the keywords post-traumatic headache, post-traumatic migraine headache, concussion, mild traumatic brain injury, and traumatic brain injury and the following categories: mechanism, pathophysiology, treatment, physical therapy, neurostimulation, Botox@/Onabotul...περισσότερα »
Endoscopic Transcanal Retrocochlear Approach to the Internal Auditory Canal with Cochlear Preservation: Pilot Cadaveric Study
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Endoscopic Transcanal Retrocochlear Approach to the Internal Auditory Canal with Cochlear Preservation: Pilot Cadaveric Study: Contemporary operative approaches to the internal auditory canal (IAC) require the creation of large surgical portals for visualization with associated morbidity, including hearing loss, vestibular dysfunction, facial nerve injury, and skull base defects that increase the risk of cerebrospinal fluid leak. Transcanal approaches to the IAC have been possible only via a transcochlear technique. To preserve cochlear function, we describe a novel endoscopic tran... περισσότερα »
Oral Antibiotic Use for Otitis Media with Effusion: Ongoing Opportunities for Quality Improvement
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Oral Antibiotic Use for Otitis Media with Effusion: Ongoing Opportunities for Quality Improvement: Objectives (1) To evaluate the probability of antibiotic administration associated with *ICD-9* diagnosis of otitis media with effusion (OME) in the absence of acute otitis media, (2) to determine whether usage varies according to visit setting, and (3) to ascertain if practice gaps are such that future practice changes might be measured. Study Design Cross-sectional analysis of an administrative database. Setting Ambulatory visits in the United States. Subjects and Methods Nationa... περισσότερα »
Biofilms Role in Chronic Cholesteatomatous Otitis Media: A Pilot Study
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Biofilms Role in Chronic Cholesteatomatous Otitis Media: A Pilot Study: Cholesteatoma is a destructive lesion involving the temporal bone, which may induce severe complications due to its expansion and erosion of adjacent structures. Bacterial biofilm plays a crucial role in the pathogenesis of many otolaryngologic inflammatory/infectious chronic diseases. In this pilot study, we investigated, by means of cultural examination and with scanning electron microscope, the presence of bacterial biofilm in a series of samples from the epitympanic and mastoid region in patients affected b... περισσότερα »
Prevalence and Characteristics of Positional Nystagmus in Normal Subjects
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Prevalence and Characteristics of Positional Nystagmus in Normal Subjects: Objective In clinical practice, patients are often referred due to a finding of positional nystagmus that does not always appear to correlate with clinical symptoms of benign paroxysmal positional vertigo. To know when to consider nystagmus to be of clinical relevance, it is necessary to know the prevalence and characteristics of positional nystagmus in a healthy population. Study Design Case series of 75 healthy subjects. Setting Two tertiary referral centers in Norway. Subjects and Methods Seventy-five... περισσότερα »
Quantitative Proteomics of Vestibular Schwannoma Cerebrospinal Fluid: A Pilot Study
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Quantitative Proteomics of Vestibular Schwannoma Cerebrospinal Fluid: A Pilot Study: This pilot study aimed to identify candidate proteins for future study that are differentially expressed in vestibular schwannoma (VS) cerebrospinal fluid (CSF) and to compare such proteins with those previously identified in perilymph and specimen secretions. CSF was collected intraoperatively prior to removal of untreated sporadic VS (3 translabyrinthine, 3 middle cranial fossa approaches) and compared with reference CSF samples. After proteolytic digestion and iTRAQ labeling, tandem mass spectro...περισσότερα »
Postoperative Calcium Management in Same-Day Discharge Thyroid and Parathyroid Surgery
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Postoperative Calcium Management in Same-Day Discharge Thyroid and Parathyroid Surgery: Objective To describe a safe and effective postoperative prophylactic calcium regimen for same-day discharge thyroid and parathyroid surgery. Study Design Case series with chart review. Setting Tertiary referral academic institution. Subjects and Methods In total, 162 adult patients who underwent total thyroidectomy, completion thyroidectomy, unilateral parathyroidectomy, parathyroidectomy with bilateral neck exploration, or revision parathyroidectomy were identified preoperatively to be cand... περισσότερα »
Parathyroid 4D CT and Scintigraphy: What Factors Contribute to Missed Parathyroid Lesions?
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Parathyroid 4D CT and Scintigraphy: What Factors Contribute to Missed Parathyroid Lesions?: Objective To determine the prevalence of missed lesions for parathyroid 4-dimensional computed tomography (4D CT) and scintigraphy and to describe the factors leading to missed lesions for both modalities. Study Design Case series with chart review. Setting Single center, hospital based. Subjects and Methods Forty patients undergoing 4D CT and scintigraphy before parathyroidectomy between July 2009 and October 2013 were included. Radiology reports and imaging were reviewed and correlated ... περισσότερα »
Outcomes and Prognostic Factors of Radiation-Induced and De Novo Head and Neck Squamous Cell Carcinomas
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Outcomes and Prognostic Factors of Radiation-Induced and De Novo Head and Neck Squamous Cell Carcinomas: Objective We sought to compare clinical outcomes, pathological features, treatment patterns, and survival outcomes between radiation-induced squamous cell carcinoma (RISCC) and de novo SCC (DNSCC) of the head and neck, as well as identify prognostic factors in these patients. Study Design Case-control study. Setting Tertiary medical center. Subjects and Methods Retrospective case-control analysis of 34 RISCCs and 136 DNSCCs matched by age at diagnosis, sex, smoking status, an... περισσότερα »
Transoral Robotic Surgery for Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Transoral Robotic Surgery for Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis: Objective To perform a systematic review of the international biomedical literature evaluating the effectiveness, complications, and safety of transoral robotic surgery (TORS) for the treatment of obstructive sleep apnea (OSA). Data Sources PubMed/MEDLINE, Embase, and EMB Reviews databases were searched up to November 27, 2015. Review Methods Two authors systematically and independently searched for articles on TORS for the treatment of OSA in adults that reported either outcomes for the ... περισσότερα »
Safety of Ultrasound-Guided Botulinum Toxin Injections for Sialorrhea as Performed by Pediatric Otolaryngologists
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Safety of Ultrasound-Guided Botulinum Toxin Injections for Sialorrhea as Performed by Pediatric Otolaryngologists: Objective To evaluate incidence of complications and hospital readmission as a result of ultrasound-guided botulinum toxin injections to manage sialorrhea. Study Design Case series with chart review. Setting Children’s Hospital of Wisconsin. Subjects and Methods A case series with chart review was performed of all cases of ultrasound-guided injection of botulinum toxin by pediatric otolaryngologists from March 5, 2010, to September 26, 2014. Primary outcomes include...περισσότερα »
BRAF(V600E) Mutation is Associated with Decreased Disease-Free Survival in Papillary Thyroid Cancer.
Alexandros G. SfakianakisστοHead and NeckΠριν από 15 δευτερόλεπτα
*BRAF(V600E) Mutation is Associated with Decreased Disease-Free Survival in Papillary Thyroid Cancer.* World J Surg. 2016 May 2; Authors: Fraser S, Go C, Aniss A, Sidhu S, Delbridge L, Learoyd D, Clifton-Bligh R, Tacon L, Tsang V, Robinson B, Gill AJ, Sywak M Abstract BACKGROUND: The BRAF (V600E) mutation is a recognised molecular marker in papillary thyroid cancer (PTC), reported incidence from 30 to 80 %. BRAF(V600E) aberrantly activates the MAPK pathway, a central regulator of cell growth and proliferation. Previous studies have reported conflicting data regarding the impact o...περισσότερα »
CRIBRIFORM-MORULAR VARIANT OF THYROID CANCER - A RED FLAG FOR FAMILIAL ADENOMATOUS POLYPOSIS.
Alexandros G. SfakianakisστοHead and NeckΠριν από 15 δευτερόλεπτα
*CRIBRIFORM-MORULAR VARIANT OF THYROID CANCER - A RED FLAG FOR FAMILIAL ADENOMATOUS POLYPOSIS.* J La State Med Soc. 2015 May-Jun;167(3):148-149 Authors: Nair Md R, Sun Md GC Abstract INTRODUCTION: Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome characterized by the development of colorectal adenomas which may be caused by mutations of the Adenomatosis polyposis colon gene. Patients with FAP are at risk for several additional intestinal malignancies including well-differentiated thyroid cancer, childhood hepatoblastoma, and central nervous system tumors. Cri... περισσότερα »
Evidence-based guidelines for recommending cochlear implantation for young children: Audiological criteria and optimizing age at implantation
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 19 δευτερόλεπτα
10.3109/14992027.2016.1157268<br>Jaime R. Leigh from #Audiology via ola Kala on Inoreader http://ift.tt/21weyWA via IFTTT
Evidence-based guidelines for recommending cochlear implantation for young children: Audiological criteria and optimizing age at implantation
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 20 δευτερόλεπτα
10.3109/14992027.2016.1157268<br>Jaime R. Leigh from #Audiology via xlomafota13 on Inoreader http://ift.tt/21weyWA via IFTTT
The correlation between ECochG parameters and early auditory behavior after cochlear implantation in children.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 20 δευτερόλεπτα
*The correlation between ECochG parameters and early auditory behavior after cochlear implantation in children.* Int J Audiol. 2016 May 3;:1-7 Authors: Stuermer KJ, Beutner D, Streicher B, Foerst A, Felsch M, Lang-Roth R, Walger M Abstract OBJECTIVE: The individual outcome after cochlear implantation in children with auditory synaptopathy/neuropathy (AS/AN) is difficult to predict. A tool for preoperative assessment would be helpful for counseling parents. This study evaluates the outcome after CI in children with AS/AN and with sensorineural hearing loss (SNHL), and correlates i...περισσότερα »
Influence of stimulation position on the sensitivity for bone conduction hearing aids without skin penetration.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 20 δευτερόλεπτα
*Influence of stimulation position on the sensitivity for bone conduction hearing aids without skin penetration.* Int J Audiol. 2016 May 3;:1-8 Authors: Dobrev I, Stenfelt S, Röösli C, Bolt L, Pfiffner F, Gerig R, Huber A, Sim JH Abstract OBJECTIVE: This study explores the influence of stimulation position on bone conduction (BC) hearing sensitivity with a BC transducer attached using a headband. DESIGN: (1) The cochlear promontory motion was measured in cadaver heads using laser Doppler vibrometry while seven different positions around the pinna were stimulated using a bone anch... περισσότερα »
Prosthodontic rehabilitation of completely edentulous patient with partial glossectomy.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
*Prosthodontic rehabilitation of completely edentulous patient with partial glossectomy.* J Indian Prosthodont Soc. 2016 Apr-Jun;16(2):204-207 Authors: Garg A Abstract Oral cancer accounts for about 40% of all cancers inflicting the human beings. Those involving the tongue results in mild to severe deficiencies of phonation, deglutition, mastication, and taste depending upon the degree and extent tissues involved. Often rehabilitation of such patient is a challenge for the prosthodontist and involves a careful observation and evaluation of the residual oral function and ways to r... περισσότερα »
A 34-year-old man with refractory heartburn and intermittent dysphagia to solids.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
*A 34-year-old man with refractory heartburn and intermittent dysphagia to solids.* CMAJ. 2016 May 2; Authors: Pham H, Yang WH PMID: 27141037 [PubMed - as supplied by publisher] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1SNjCAo via IFTTT
OK-432 injection therapy for cystadenocarcinoma of the parotid gland: A case report.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
*OK-432 injection therapy for cystadenocarcinoma of the parotid gland: A case report.* Ear Nose Throat J. 2016 Apr-May;95(4-5):189-192 Authors: Makiyama K, Hirai R, Iikuni F, Ikeda A, Tomomatsu H Abstract OK-432 is an immunomodulator that has been reported to be efficacious as an injection therapy for cervical lymphomas and ranulas. We performed OK-432 injection therapy to treat a cystadenocarcinoma of the parotid gland in a 72-year-old man. The 50 × 46-mm tumor was located in the deep lobe of the gland. The tumor had compressed the glossopharyngeal, vagus, and hypoglossal nerves... περισσότερα »
Endoscopic-assisted transoral-transpharyngeal approach to parapharyngeal space and infratemporal fossa: focus on feasibility and lessons learned.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
*Endoscopic-assisted transoral-transpharyngeal approach to parapharyngeal space and infratemporal fossa: focus on feasibility and lessons learned.* Eur Arch Otorhinolaryngol. 2016 May 2; Authors: Dallan I, Fiacchini G, Turri-Zanoni M, Seccia V, Battaglia P, Casani AP, Cristofani-Mencacci L, Sellari-Franceschini S Abstract The parapharyngeal space (PPS) is a challenging anatomical region, rich in vascular and nervous vital structures. Surgery is considered the treatment of choice for the majority of PPS lesions. Herein, we present a retrospective evaluation on ten patients with var... περισσότερα »
Clinical Case of the Month: A 48-Year-Old Man With Fever and Abdominal Pain of One Day Duration.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
*Clinical Case of the Month: A 48-Year-Old Man With Fever and Abdominal Pain of One Day Duration.* J La State Med Soc. 2015 Sep-Oct;167(5):237-240 Authors: Yu Md M, Tadin Md D, Conrad Md EJ, Lopez Md FA Abstract A 48-year-old man residing in a mental health department inpatient program with a history of schizoaffective disorder presented to the emergency department with a chief complaint of fever and intense abdominal pain for one day. The patient stated he initially fell in the shower and afterwards experienced back pain. He was transferred to an acute care unit within the facil...περισσότερα »
THE ACHES THAT TAKE YOUR BREATH (AND TEARS) AWAY.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
*THE ACHES THAT TAKE YOUR BREATH (AND TEARS) AWAY.* J La State Med Soc. 2015 May-Jun;167(3):154-155 Authors: Becerril Md J, Gonzales Md H, Saketkoo Md LA Abstract CASE: An 80-year-old man presented with a complaint of three months of fatigue and aching of his shoulders and hips, as well as pain, swelling, and stiffness in bilateral fingers that was worse in the morning but improved with movement. Associated symptoms included worsening dry mouth and eyes, dysphagia, exertional dyspnea, and right foot drop. Physical exam was significant for edematous and tender bilateral proximal in... περισσότερα »
Does cervical disc arthroplasty have lower incidence of dysphagia than anterior cervical discectomy and fusion? A meta-analysis.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
*Does cervical disc arthroplasty have lower incidence of dysphagia than anterior cervical discectomy and fusion? A meta-analysis.* Clin Neurol Neurosurg. 2016 Apr 4;146:45-51 Authors: Zhong ZM, Li M, Han ZM, Zeng JH, Zhu SY, Wu Q, Chen JT Abstract OBJECTIVE: Dysphagia is a common occurrence after anterior cervical spine surgery. The aim of this meta-analysis was to evaluate the incidence of dysphagia after ervical disc arthroplasty (CDA) compared with anterior cervical discectomy and fusion (ACDF). MATERIAL AND METHODS: The electronic databases, including PubMed, EMBASE and Cochra... περισσότερα »
The Multidisciplinary Swallowing Team Approach Decreases Pneumonia Onset in Acute Stroke Patients.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
*The Multidisciplinary Swallowing Team Approach Decreases Pneumonia Onset in Acute Stroke Patients.* PLoS One. 2016;11(5):e0154608 Authors: Aoki S, Hosomi N, Hirayama J, Nakamori M, Yoshikawa M, Nezu T, Kubo S, Nagano Y, Nagao A, Yamane N, Nishikawa Y, Takamoto M, Ueno H, Ochi K, Maruyama H, Yamamoto H, Matsumoto M, Hiroshima University Hospital Stroke Swallowing Team Abstract Dysphagia occurs in acute stroke patients at high rates, and many of them develop aspiration pneumonia. Team approaches with the cooperation of various professionals have the power to improve the quality of... περισσότερα »
Change in Angular Alignment is Associated With Early Dysphagia After Anterior Cervical Diskectomy and Fusion.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
*Change in Angular Alignment is Associated With Early Dysphagia After Anterior Cervical Diskectomy and Fusion.* Clin Spine Surg. 2016 May 2; Authors: Radcliff KE, Bennett J, Stewart RJ, Kepler CK, Sidhu GS, Hilibrand AS, Kane J, Albert TJ, Vaccaro AR, Rihn JA Abstract STUDY DESIGN: Retrospective analysis of a prospective cohort. OBJECTIVE: Change in cervical angular alignment may be associated with dysphagia. SUMMARY OF BACKGROUND DATA: Bony deformities of the cervical spine may be associated with secondary contractures in soft tissues in the neck. Acute surgical deformity correct... περισσότερα »
Reply to the Letter to Editor by Maeda et al.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Reply to the Letter to Editor by Maeda et al.* J Am Med Dir Assoc. 2015 Oct 1;16(10):897 Authors: Lee JS, Kwok T PMID: 26433863 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1SNhwR1 via IFTTT
Injection laryngoplasty in children with cystic fibrosis and abnormal swallow.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Injection laryngoplasty in children with cystic fibrosis and abnormal swallow.* Int J Pediatr Otorhinolaryngol. 2015 Nov;79(11):1856-9 Authors: Virbalas J, McMullen C, Cheng J Abstract OBJECTIVE: Children with cystic fibrosis (CF) are uniquely vulnerable to the pulmonary complications of chronic aspiration. We present a case series of children with CF and evidence of chronic aspiration who underwent injection laryngoplasty to improve the safety and efficacy of their swallow. STUDY DESIGN: Retrospective chart revie... περισσότερα »
Angiotensin-Converting Enzyme Inhibitor in Tube-Fed Patients With Stroke History.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Angiotensin-Converting Enzyme Inhibitor in Tube-Fed Patients With Stroke History.* J Am Med Dir Assoc. 2015 Oct 1;16(10):896-7 Authors: Maeda K, Wakabayashi H, Shamoto H PMID: 26297619 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1W71wyS via IFTTT
Peroral endoscopic myotomy for esophageal muscular ring.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
[image: http:--http://ift.tt/1SvbKVd] Related Articles *Peroral endoscopic myotomy for esophageal muscular ring.* Endoscopy. 2015;47 Suppl 1 UCTN:E387-8 Authors: Song GW, Ko WJ, Kim WH, Hahm KB, Hong SP, Cho JY PMID: 26273774 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1SNhwQQ via IFTTT
Esophageal hematoma after peroral endoscopic myotomy for achalasia in a patient on antiplatelet therapy.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
[image: http:--http://ift.tt/1SvbKVd] Related Articles *Esophageal hematoma after peroral endoscopic myotomy for achalasia in a patient on antiplatelet therapy.* Endoscopy. 2015;47 Suppl 1 UCTN:E363-4 Authors: Benech N, Pioche M, O'Brien M, Rivory J, Roman S, Mion F, Ponchon T PMID: 26262447 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/26SDM5m via IFTTT
Central Nervous System Control of Voice and Swallowing.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Central Nervous System Control of Voice and Swallowing.* J Clin Neurophysiol. 2015 Aug;32(4):294-303 Authors: Ludlow CL Abstract This review of the central nervous control systems for voice and swallowing has suggested that the traditional concepts of a separation between cortical and limbic and brain stem control should be refined and be more integrative. For voice production, a separation of the nonhuman vocalization system from the human learned voice production system has been posited based primarily on studi... περισσότερα »
Detecting laryngopharyngeal reflux in patients with upper airways symptoms: Symptoms, signs or salivary pepsin?
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 31 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Detecting laryngopharyngeal reflux in patients with upper airways symptoms: Symptoms, signs or salivary pepsin?* Respir Med. 2015 Aug;109(8):963-9 Authors: Spyridoulias A, Lillie S, Vyas A, Fowler SJ Abstract BACKGROUND: Laryngopharyngeal reflux (LPR) can induce laryngeal hyper-responsiveness, a unifying feature underlying chronic cough and vocal cord dysfunction. The diagnosis of LPR currently relies on invasive oesophageal pH impedance testing. We compared symptoms, laryngeal signs and salivary pepsin as potent... περισσότερα »
Investment Specialist!
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
Dear Sir/Madam, I am Barrister John Anthony, Esq. An Investment Consultant/Legal Adviser. My client is interested in investing the sums of US$ 36 Million (Thirty Six Million Dollars) in your country with the partnership of your company. If you are interest in this offer kindly respond and give us your full contact details plus company profile and in respond we will send you an elaborate proposal and details of the offer. Thanks, John Anthony, Esq.
Barriers to early cochlear implantation.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 35 δευτερόλεπτα
*Barriers to early cochlear implantation.* Int J Audiol. 2016 May 3;:1-13 Authors: Dettman S, Choo D, Dowell R Abstract OBJECTIVE: Identify variables associated with paediatric access to cochlear implants (CIs). DESIGN: Part 1. Trends over time for age at CI surgery (N = 802) and age at hearing aid (HA) fitting (n = 487) were examined with regard to periods before, during, and after newborn hearing screening (NHS). Part 2. Demographic factors were explored for 417 children implanted under 3 years of age. Part 3. Pre-implant steps for the first 20 children to receive CIs under 12 ... περισσότερα »
Development of Telscreen: a telephone-based speech-in-noise hearing screening test with a novel masking noise and scoring procedure.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 35 δευτερόλεπτα
*Development of Telscreen: a telephone-based speech-in-noise hearing screening test with a novel masking noise and scoring procedure.* Int J Audiol. 2016 May 3;:1-9 Authors: Dillon H, Beach EF, Seymour J, Carter L, Golding M Abstract OBJECTIVE: In 2006 the National Acoustic Laboratories was commissioned to create a telephone-based hearing screening test. DESIGN: NAL developed 'Telscreen', a speech-in-noise test modelled on the Dutch and UK telephone tests. The first version, Telscreen I, had several novel features: individual scoring of digits; individual equalization of digit int... περισσότερα »
Applying theories of health behaviour and change to hearing health research: Time for a new approach.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 35 δευτερόλεπτα
*Applying theories of health behaviour and change to hearing health research: Time for a new approach.* Int J Audiol. 2016 May 3;:1-6 Authors: Coulson NS, Ferguson MA, Henshaw H, Heffernan E Abstract OBJECTIVE: In recent years, there has been an increase in the application of behavioural models, such as social cognition models, to the promotion of hearing health. Despite this, there exists a well-developed body of literature that suggests such models may fail to consistently explain reliable amounts of variability in human behaviours. DESIGN: This paper provides a summary of this ... περισσότερα »
PulmCrit Wee: Ultrasound-guided blakemore tube placement
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
[image: usguide.gif?resize=750%2C285] The most widely feared complication of placing a Blakemore tube is complete inflation of the gastric balloon while it is not in the stomach. If the gastric balloon is fully inflated anywhere outside the stomach (i.e. esophagus, trachea, bronchus, duodenum), this may cause visceral perforation. EMCrit by Josh Farkas. from #Rehabilitation via ola Kala on Inoreader http://ift.tt/23oGECE via IFTTT
Prosthodontic rehabilitation of completely edentulous patient with partial glossectomy.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
*Prosthodontic rehabilitation of completely edentulous patient with partial glossectomy.* J Indian Prosthodont Soc. 2016 Apr-Jun;16(2):204-207 Authors: Garg A Abstract Oral cancer accounts for about 40% of all cancers inflicting the human beings. Those involving the tongue results in mild to severe deficiencies of phonation, deglutition, mastication, and taste depending upon the degree and extent tissues involved. Often rehabilitation of such patient is a challenge for the prosthodontist and involves a careful observation and evaluation of the residual oral function and ways to r... περισσότερα »
The Multidisciplinary Swallowing Team Approach Decreases Pneumonia Onset in Acute Stroke Patients.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
*The Multidisciplinary Swallowing Team Approach Decreases Pneumonia Onset in Acute Stroke Patients.* PLoS One. 2016;11(5):e0154608 Authors: Aoki S, Hosomi N, Hirayama J, Nakamori M, Yoshikawa M, Nezu T, Kubo S, Nagano Y, Nagao A, Yamane N, Nishikawa Y, Takamoto M, Ueno H, Ochi K, Maruyama H, Yamamoto H, Matsumoto M, Hiroshima University Hospital Stroke Swallowing Team Abstract Dysphagia occurs in acute stroke patients at high rates, and many of them develop aspiration pneumonia. Team approaches with the cooperation of various professionals have the power to improve the quality of... περισσότερα »
Angiotensin-Converting Enzyme Inhibitor in Tube-Fed Patients With Stroke History.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Angiotensin-Converting Enzyme Inhibitor in Tube-Fed Patients With Stroke History.* J Am Med Dir Assoc. 2015 Oct 1;16(10):896-7 Authors: Maeda K, Wakabayashi H, Shamoto H PMID: 26297619 [PubMed - indexed for MEDLINE] from #Rehabilitation via ola Kala on Inoreader http://ift.tt/1W71wyS via IFTTT
Evidence-based guidelines for recommending cochlear implantation for young children: Audiological criteria and optimizing age at implantation
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 43 δευτερόλεπτα
10.3109/14992027.2016.1157268<br>Jaime R. Leigh from #Audiology via ola Kala on Inoreader http://ift.tt/1ZbUvec via IFTTT
The correlation between ECochG parameters and early auditory behavior after cochlear implantation in children.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 43 δευτερόλεπτα
*The correlation between ECochG parameters and early auditory behavior after cochlear implantation in children.* Int J Audiol. 2016 May 3;:1-7 Authors: Stuermer KJ, Beutner D, Streicher B, Foerst A, Felsch M, Lang-Roth R, Walger M Abstract OBJECTIVE: The individual outcome after cochlear implantation in children with auditory synaptopathy/neuropathy (AS/AN) is difficult to predict. A tool for preoperative assessment would be helpful for counseling parents. This study evaluates the outcome after CI in children with AS/AN and with sensorineural hearing loss (SNHL), and correlates i...περισσότερα »
Influence of stimulation position on the sensitivity for bone conduction hearing aids without skin penetration.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 43 δευτερόλεπτα
*Influence of stimulation position on the sensitivity for bone conduction hearing aids without skin penetration.* Int J Audiol. 2016 May 3;:1-8 Authors: Dobrev I, Stenfelt S, Röösli C, Bolt L, Pfiffner F, Gerig R, Huber A, Sim JH Abstract OBJECTIVE: This study explores the influence of stimulation position on bone conduction (BC) hearing sensitivity with a BC transducer attached using a headband. DESIGN: (1) The cochlear promontory motion was measured in cadaver heads using laser Doppler vibrometry while seven different positions around the pinna were stimulated using a bone anch... περισσότερα »
Barriers to early cochlear implantation.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 43 δευτερόλεπτα
*Barriers to early cochlear implantation.* Int J Audiol. 2016 May 3;:1-13 Authors: Dettman S, Choo D, Dowell R Abstract OBJECTIVE: Identify variables associated with paediatric access to cochlear implants (CIs). DESIGN: Part 1. Trends over time for age at CI surgery (N = 802) and age at hearing aid (HA) fitting (n = 487) were examined with regard to periods before, during, and after newborn hearing screening (NHS). Part 2. Demographic factors were explored for 417 children implanted under 3 years of age. Part 3. Pre-implant steps for the first 20 children to receive CIs under 12 ... περισσότερα »
Conversion of Nissen fundoplication to laparoscopic gastric bypass: video case report and literature review.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 43 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Conversion of Nissen fundoplication to laparoscopic gastric bypass: video case report and literature review.* Surg Obes Relat Dis. 2015 Jul-Aug;11(4):973-4 Authors: Thereaux J, Roche C, Bail JP PMID: 26003900 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1SNhvfL via IFTTT
Application of simple swallowing provocation test with fiberoptic endoscopic evaluation of swallowing in a cross-sectional study.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 43 δευτερόλεπτα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Application of simple swallowing provocation test with fiberoptic endoscopic evaluation of swallowing in a cross-sectional study.* BMC Geriatr. 2015;15:48 Authors: Tejima C, Kikutani T, Takahashi N, Tamura F, Yoshida M Abstract BACKGROUND: This study aimed to develop a simultaneously swallowing provocation test for dysphagia patients undergoing fiberoptic endoscopic evaluation of swallowing (FEES), as well as to evaluate its efficacy. METHODS: In this test, 0·4 and 2·0 mL volumes of water... περισσότερα »
The effect of concurrent esophageal pathology on bariatric surgical planning.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 43 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *The effect of concurrent esophageal pathology on bariatric surgical planning.* J Gastrointest Surg. 2015 Jan;19(1):111-5; discussion 115-6 Authors: Bradley DD, Louie BE, Chen J, Aye RW, McMahon R, Farivar AS Abstract In the presence of esophageal pathology, there is risk of worse outcomes after laparoscopic adjustable gastric banding (LAGB) and sleeve gastrectomy (SG). This study reviewed how an esophageal workup affected a bariatric operative plan in patients with concurrent esophageal pathology. We retrospectiv...περισσότερα »
Peroral endoscopic myotomy (POEM) for esophageal primary motility disorders: analysis of 100 consecutive patients.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 43 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *Peroral endoscopic myotomy (POEM) for esophageal primary motility disorders: analysis of 100 consecutive patients.* J Gastrointest Surg. 2015 Jan;19(1):161-70; discussion 170 Authors: Sharata AM, Dunst CM, Pescarus R, Shlomovitz E, Wille AJ, Reavis KM, Swanström LL Abstract INTRODUCTION: Peroral endoscopic myotomy (POEM) is a flexible endoscopic approach to the lower esophageal sphincter (LES) providing access for a myotomy to relieve dysphagia. The technique has been adopted worldwide due to reports of excellent... περισσότερα »
A 34-year-old man with refractory heartburn and intermittent dysphagia to solids.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 43 δευτερόλεπτα
*A 34-year-old man with refractory heartburn and intermittent dysphagia to solids.* CMAJ. 2016 May 2; Authors: Pham H, Yang WH PMID: 27141037 [PubMed - as supplied by publisher] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1SNjCAo via IFTTT
OK-432 injection therapy for cystadenocarcinoma of the parotid gland: A case report.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 43 δευτερόλεπτα
*OK-432 injection therapy for cystadenocarcinoma of the parotid gland: A case report.* Ear Nose Throat J. 2016 Apr-May;95(4-5):189-192 Authors: Makiyama K, Hirai R, Iikuni F, Ikeda A, Tomomatsu H Abstract OK-432 is an immunomodulator that has been reported to be efficacious as an injection therapy for cervical lymphomas and ranulas. We performed OK-432 injection therapy to treat a cystadenocarcinoma of the parotid gland in a 72-year-old man. The 50 × 46-mm tumor was located in the deep lobe of the gland. The tumor had compressed the glossopharyngeal, vagus, and hypoglossal nerves... περισσότερα »
Endoscopic-assisted transoral-transpharyngeal approach to parapharyngeal space and infratemporal fossa: focus on feasibility and lessons learned.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 43 δευτερόλεπτα
*Endoscopic-assisted transoral-transpharyngeal approach to parapharyngeal space and infratemporal fossa: focus on feasibility and lessons learned.* Eur Arch Otorhinolaryngol. 2016 May 2; Authors: Dallan I, Fiacchini G, Turri-Zanoni M, Seccia V, Battaglia P, Casani AP, Cristofani-Mencacci L, Sellari-Franceschini S Abstract The parapharyngeal space (PPS) is a challenging anatomical region, rich in vascular and nervous vital structures. Surgery is considered the treatment of choice for the majority of PPS lesions. Herein, we present a retrospective evaluation on ten patients with var... περισσότερα »
Clinical Case of the Month: A 48-Year-Old Man With Fever and Abdominal Pain of One Day Duration.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 43 δευτερόλεπτα
*Clinical Case of the Month: A 48-Year-Old Man With Fever and Abdominal Pain of One Day Duration.* J La State Med Soc. 2015 Sep-Oct;167(5):237-240 Authors: Yu Md M, Tadin Md D, Conrad Md EJ, Lopez Md FA Abstract A 48-year-old man residing in a mental health department inpatient program with a history of schizoaffective disorder presented to the emergency department with a chief complaint of fever and intense abdominal pain for one day. The patient stated he initially fell in the shower and afterwards experienced back pain. He was transferred to an acute care unit within the facil...περισσότερα »
Preventable and potentially preventable deaths in severely injured patients: a retrospective analysis including patterns of errors
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 49 δευτερόλεπτα
European Journal of Trauma and Emergency Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SNm6P6 via IFTTT
Measurement of oxygen consumption in critically ill children: breath-by-breath method vs mass spectrometry
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 49 δευτερόλεπτα
American Journal of Critical Care from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NVmfDe via IFTTT
Researchers identify sharp rise in hospitalizations and health care costs associated with opioid abuse
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 49 δευτερόλεπτα
Beth Israel Deaconess Medical Center from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1SNm7CN via IFTTT
Presenting symptoms in the emergency department as predictors of intensive care unit admissions and hospital mortality in a comprehensive cancer center
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 49 δευτερόλεπτα
Journal of Oncology Practice from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NVmfmH via IFTTT
Endoscopic-assisted transoral-transpharyngeal approach to parapharyngeal space and infratemporal fossa: focus on feasibility and lessons learned.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 49 δευτερόλεπτα
*Endoscopic-assisted transoral-transpharyngeal approach to parapharyngeal space and infratemporal fossa: focus on feasibility and lessons learned.* Eur Arch Otorhinolaryngol. 2016 May 2; Authors: Dallan I, Fiacchini G, Turri-Zanoni M, Seccia V, Battaglia P, Casani AP, Cristofani-Mencacci L, Sellari-Franceschini S Abstract The parapharyngeal space (PPS) is a challenging anatomical region, rich in vascular and nervous vital structures. Surgery is considered the treatment of choice for the majority of PPS lesions. Herein, we present a retrospective evaluation on ten patients with var... περισσότερα »
Clinical Case of the Month: A 48-Year-Old Man With Fever and Abdominal Pain of One Day Duration.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 49 δευτερόλεπτα
*Clinical Case of the Month: A 48-Year-Old Man With Fever and Abdominal Pain of One Day Duration.* J La State Med Soc. 2015 Sep-Oct;167(5):237-240 Authors: Yu Md M, Tadin Md D, Conrad Md EJ, Lopez Md FA Abstract A 48-year-old man residing in a mental health department inpatient program with a history of schizoaffective disorder presented to the emergency department with a chief complaint of fever and intense abdominal pain for one day. The patient stated he initially fell in the shower and afterwards experienced back pain. He was transferred to an acute care unit within the facil...περισσότερα »
THE ACHES THAT TAKE YOUR BREATH (AND TEARS) AWAY.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 49 δευτερόλεπτα
*THE ACHES THAT TAKE YOUR BREATH (AND TEARS) AWAY.* J La State Med Soc. 2015 May-Jun;167(3):154-155 Authors: Becerril Md J, Gonzales Md H, Saketkoo Md LA Abstract CASE: An 80-year-old man presented with a complaint of three months of fatigue and aching of his shoulders and hips, as well as pain, swelling, and stiffness in bilateral fingers that was worse in the morning but improved with movement. Associated symptoms included worsening dry mouth and eyes, dysphagia, exertional dyspnea, and right foot drop. Physical exam was significant for edematous and tender bilateral proximal in... περισσότερα »
Does cervical disc arthroplasty have lower incidence of dysphagia than anterior cervical discectomy and fusion? A meta-analysis.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 49 δευτερόλεπτα
*Does cervical disc arthroplasty have lower incidence of dysphagia than anterior cervical discectomy and fusion? A meta-analysis.* Clin Neurol Neurosurg. 2016 Apr 4;146:45-51 Authors: Zhong ZM, Li M, Han ZM, Zeng JH, Zhu SY, Wu Q, Chen JT Abstract OBJECTIVE: Dysphagia is a common occurrence after anterior cervical spine surgery. The aim of this meta-analysis was to evaluate the incidence of dysphagia after ervical disc arthroplasty (CDA) compared with anterior cervical discectomy and fusion (ACDF). MATERIAL AND METHODS: The electronic databases, including PubMed, EMBASE and Cochra... περισσότερα »
Development of Telscreen: a telephone-based speech-in-noise hearing screening test with a novel masking noise and scoring procedure.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 50 δευτερόλεπτα
*Development of Telscreen: a telephone-based speech-in-noise hearing screening test with a novel masking noise and scoring procedure.* Int J Audiol. 2016 May 3;:1-9 Authors: Dillon H, Beach EF, Seymour J, Carter L, Golding M Abstract OBJECTIVE: In 2006 the National Acoustic Laboratories was commissioned to create a telephone-based hearing screening test. DESIGN: NAL developed 'Telscreen', a speech-in-noise test modelled on the Dutch and UK telephone tests. The first version, Telscreen I, had several novel features: individual scoring of digits; individual equalization of digit int... περισσότερα »
Applying theories of health behaviour and change to hearing health research: Time for a new approach.
Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 50 δευτερόλεπτα
*Applying theories of health behaviour and change to hearing health research: Time for a new approach.* Int J Audiol. 2016 May 3;:1-6 Authors: Coulson NS, Ferguson MA, Henshaw H, Heffernan E Abstract OBJECTIVE: In recent years, there has been an increase in the application of behavioural models, such as social cognition models, to the promotion of hearing health. Despite this, there exists a well-developed body of literature that suggests such models may fail to consistently explain reliable amounts of variability in human behaviours. DESIGN: This paper provides a summary of this ... περισσότερα »
Microarray-based Gene Expression Profiling of Abdominal Aortic Aneurysm
Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 50 δευτερόλεπτα
Publication date: Available online 3 May 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): H.Z. Butt, N. Sylvius, M.K. Salem, J.B. Wild, N. Dattani, R.D. Sayers, M.J. Bown Objective/BackgroundMicroarray-based gene expression profiling studies may detect transcriptional signatures carrying prognostic value in abdominal aortic aneurysms (AAA). A gene expression profiling study was conducted to compare individuals with AAA with screened controls.MethodsThe peripheral blood transcriptome was compared between 12 individuals with AAA and 12 age- and sex-matche... περισσότερα »
Mechanobiology of the tooth movement during the orthodontic treatment: a literature review.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*Mechanobiology of the tooth movement during the orthodontic treatment: a literature review.* Minerva Stomatol. 2016 Mar 17; Authors: Isola G, Matarese G, Cordasco G, Perillo L, Ramaglia L Abstract Orthodontic tooth movement differs significantly from the physiological tooth movement, because it effects a biological response of the surrounding tissues of the teeth, resulting in a remodeling of the periodontal ligament and the alveolar bone. The result is a biochemical adaptive response to the application of the orthodontic force with the reorganization of the intracellular and th... περισσότερα »
Effect of different mixing methods on the bacterial microleakage of calcium-enriched mixture cement.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*Effect of different mixing methods on the bacterial microleakage of calcium-enriched mixture cement.* Minerva Stomatol. 2016 Mar 17; Authors: Shahi S, Jeddi Khajeh S, Rahimi S, Yavari HR, Jafari F, Samiei M, Ghasemi N, Salem Milani A Abstract BACKGROUND: Calcium-Enriched Mixture Cement is used in the field of endodontics. It is similar to Mineral Trioxide Aggregate in its main ingredients.The present study investigated the effect of different mixing methods on the bacterial microleakage of CEM cement. METHODS: A total of 55 human single-rooted human permanent teeth were decorona... περισσότερα »
Pharmacokinetics of cabozantinib tablet and capsule formulations in healthy adults.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*Pharmacokinetics of cabozantinib tablet and capsule formulations in healthy adults.* Anticancer Drugs. 2016 May 2; Authors: Nguyen L, Benrimoh N, Xie Y, Offman E, Lacy S Abstract Cabozantinib capsules (COMETRIQ) are approved for the treatment of patients with progressive metastatic medullary thyroid cancer. Cabozantinib tablets are investigational drug products considered to be potentially preferred pharmaceutical dosing forms. Two phase I open-label single-dose studies in healthy individuals were carried out to characterize the plasma pharmacokinetics of cabozantinib capsule an... περισσότερα »
Current Standards in Treatment of Radioiodine Refractory Thyroid Cancer.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*Current Standards in Treatment of Radioiodine Refractory Thyroid Cancer.* Curr Treat Options Oncol. 2016 Jun;17(6):30 Authors: Narayanan S, Colevas AD Abstract OPINION STATEMENT: Radioiodine refractory differentiated thyroid cancer (RAI-R DTC) is a challenging malignancy with limited prognosis and treatment options. Recently, clinical trials with targeted therapies have advanced the outlook of these patients, and inhibition of the vascular endothelial growth factor (VEGF) axis has led to the approval of small-molecule tyrosine kinase inhibitors (TKIs) for first-line treatment of... περισσότερα »
Evaluation and management of thyroid nodules in children.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*Evaluation and management of thyroid nodules in children.* Curr Opin Pediatr. 2016 Jun 30; Authors: Bauer AJ, Francis GL Abstract PURPOSE OF REVIEW: The review is focused on new information about the presentation and management of thyroid nodules in children and adolescents. RECENT FINDINGS: Palpable thyroid nodules are uncommon in children but many children have nodules detected by radiologic imaging. How to evaluate them, when to suspect thyroid cancer, and how best to follow apparently benign nodules has become an area of great interest. The American Thyroid Association recent... περισσότερα »
BRAF(V600E) Mutation is Associated with Decreased Disease-Free Survival in Papillary Thyroid Cancer.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*BRAF(V600E) Mutation is Associated with Decreased Disease-Free Survival in Papillary Thyroid Cancer.* World J Surg. 2016 May 2; Authors: Fraser S, Go C, Aniss A, Sidhu S, Delbridge L, Learoyd D, Clifton-Bligh R, Tacon L, Tsang V, Robinson B, Gill AJ, Sywak M Abstract BACKGROUND: The BRAF (V600E) mutation is a recognised molecular marker in papillary thyroid cancer (PTC), reported incidence from 30 to 80 %. BRAF(V600E) aberrantly activates the MAPK pathway, a central regulator of cell growth and proliferation. Previous studies have reported conflicting data regarding the impact o...περισσότερα »
CRIBRIFORM-MORULAR VARIANT OF THYROID CANCER - A RED FLAG FOR FAMILIAL ADENOMATOUS POLYPOSIS.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*CRIBRIFORM-MORULAR VARIANT OF THYROID CANCER - A RED FLAG FOR FAMILIAL ADENOMATOUS POLYPOSIS.* J La State Med Soc. 2015 May-Jun;167(3):148-149 Authors: Nair Md R, Sun Md GC Abstract INTRODUCTION: Familial adenomatous polyposis (FAP) is an autosomal dominant syndrome characterized by the development of colorectal adenomas which may be caused by mutations of the Adenomatosis polyposis colon gene. Patients with FAP are at risk for several additional intestinal malignancies including well-differentiated thyroid cancer, childhood hepatoblastoma, and central nervous system tumors. Cri... περισσότερα »
[Nodules are frequent - cancer is rare].
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*[Nodules are frequent - cancer is rare].* MMW Fortschr Med. 2015 Nov 19;157(20):62-3 Authors: PMID: 26977520 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1ZbGT2O via IFTTT
Radiofrequency and Cryo-ablation Effect on Transvenous Pacing and Defibrillatory Lead Integrity: An in vitro study.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*Radiofrequency and Cryo-ablation Effect on Transvenous Pacing and Defibrillatory Lead Integrity: An in vitro study.* J Cardiovasc Electrophysiol. 2016 May 3; Authors: Darrat YH, Agarwal A, Morales GX, Thompson J, Abdel-Latif A, Waespe K, Biase LD, Natale A, Patwardan A, Elayi CS Abstract INTORDUCTION: Medical societies and cardiac implantable electronic devices (CIED) manufacturers recommend avoiding close or direct contact between the body of transvenous leads and ablation catheters used to treat cardiac arrhythmias. These recommendations are made despite the lack of clinical s...περισσότερα »
NEVER SEEMS TO GROW PAINS: A CASE OF SUSPECTED PSEUDOSEPTIC ARTHRITIS.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*NEVER SEEMS TO GROW PAINS: A CASE OF SUSPECTED PSEUDOSEPTIC ARTHRITIS.* J La State Med Soc. 2015 May-Jun;167(3):149-150 Authors: Alrehaili Md M, Harless Md A, Bateman Md L Abstract INTRODUCTION: Pseudoseptic arthritis is an acute inflammatory arthritis found in association with a sterile synovial fluid culture despite white blood cell (WBC) counts >100,000 and >75% polymorph neutrophils. This arthritis occurs most frequently in patients with underlying inflammatory or immune disorders. Early distinction from true septic arthritis can decrease the need for unnecessary antibiotics ... περισσότερα »
Wolff-Parkinson-White and left ventricular noncompaction in a Fabry patient: A case report.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*Wolff-Parkinson-White and left ventricular noncompaction in a Fabry patient: A case report.* Turk Kardiyol Dern Ars. 2016 Apr;44(3):248-250 Authors: Alper AT, Kaya A, Tekkesin Aİ, Öz A Abstract Fabry disease is the second most common inherited (X-linked recessive) lysosomal storage disease associated with multiple organ involvement. Cardiac involvement of Fabry disease varies. Successful radiofrequency ablation of a Fabry disease patient with Wolff-Parkinson-White syndrome and left ventricular noncompaction is described in the present report. PMID: 27138316 [PubMed - as supplied...περισσότερα »
Percutaneous treatment of extrahepatic recurrence of hepatocellular carcinoma.
Alexandros G. SfakianakisστοHead and NeckΠριν από 53 δευτερόλεπτα
*Percutaneous treatment of extrahepatic recurrence of hepatocellular carcinoma.* Diagn Interv Imaging. 2016 Apr 29; Authors: Doreille A, N'Kontchou G, Halimi A, Bouhafs F, Coderc E, Sellier N, Seror O Abstract PURPOSE: The goal of this study was to retrospectively evaluate the results of imaging-guided percutaneous ablation in patients with controlled intrahepatic hepatocellular carcinoma (HCC) with limited extrahepatic disease. MATERIALS AND METHODS: Eleven patients with limited extrahepatic disease and/or potential short-term clinical manifestations with controlled primary int...περισσότερα »
THE ACHES THAT TAKE YOUR BREATH (AND TEARS) AWAY.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 53 δευτερόλεπτα
*THE ACHES THAT TAKE YOUR BREATH (AND TEARS) AWAY.* J La State Med Soc. 2015 May-Jun;167(3):154-155 Authors: Becerril Md J, Gonzales Md H, Saketkoo Md LA Abstract CASE: An 80-year-old man presented with a complaint of three months of fatigue and aching of his shoulders and hips, as well as pain, swelling, and stiffness in bilateral fingers that was worse in the morning but improved with movement. Associated symptoms included worsening dry mouth and eyes, dysphagia, exertional dyspnea, and right foot drop. Physical exam was significant for edematous and tender bilateral proximal in... περισσότερα »
Does cervical disc arthroplasty have lower incidence of dysphagia than anterior cervical discectomy and fusion? A meta-analysis.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 53 δευτερόλεπτα
*Does cervical disc arthroplasty have lower incidence of dysphagia than anterior cervical discectomy and fusion? A meta-analysis.* Clin Neurol Neurosurg. 2016 Apr 4;146:45-51 Authors: Zhong ZM, Li M, Han ZM, Zeng JH, Zhu SY, Wu Q, Chen JT Abstract OBJECTIVE: Dysphagia is a common occurrence after anterior cervical spine surgery. The aim of this meta-analysis was to evaluate the incidence of dysphagia after ervical disc arthroplasty (CDA) compared with anterior cervical discectomy and fusion (ACDF). MATERIAL AND METHODS: The electronic databases, including PubMed, EMBASE and Cochra... περισσότερα »
Subtotal Petrosectomy for Cochlear Implantation: Lessons Learned After 110 Cases
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 53 δευτερόλεπτα
Objectives: The purpose of this study was to review the indications for subtotal petrosectomy for cochlear implantation, report our management of complications, as well as review those technical factors that are critical for successful implantation. Methods: Patients (n = 104) that underwent subtotal petrosectomy with closure of the external auditory canal and obliteration of the cavity with abdominal fat in combination with cochlear implantation were analyzed. Results: The most frequent indication for subtotal petrosectomy was the existence of a previous canal wall down techn... περισσότερα »
Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Positive Otitis Media and Rhinosinusitis With Pathological Features of Immunoglobulin G4-Related Disease: A Case Report
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Background: Immunoglobulin G4-related disease (IgG4-RD) and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) have different clinical and pathological features. However, differentiation between these 2 disorders is sometimes difficult. Objective: To report a case involving a patient with characteristics of both IgG4-RD and AAV. Methods: Case report with literature review. Results: We report a case of myeloperoxidase-ANCA–positive otitis media and rhinosinusitis with pathological features of IgG4-RD in a 73-year-old man. The patient was first clinically s... περισσότερα »
Glottic Cancer: A Metamorphosing Disease
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Objective: Conventional wisdom is that the overwhelming majority of glottic cancer patients have a smoking history. However, in recent years observations suggested that an increasing number of glottic cancer patients had never been smokers. Therefore, an investigation was done examining the incidence of having a smoking history in a recent cohort of glottic cancer patients. Method: Retrospective review of 100 patients with glottic cancer to determine those reporting never having smoked. Results: Thirty-one of 100 did not have a smoking history. Clinical observations of those c... περισσότερα »
Device Life of Two Generations of Provox Voice Prostheses
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Background: Tracheoesophageal voice prostheses are invaluable for speech rehabilitation in patients who have received total laryngectomy, but device failure impedes communication and creates psychosocial and financial burdens. This study compares the Provox 2 and Provox Vega voice prostheses on the parameter of device life. Methods: This was a retrospective observational study of 21 patients with 181 device replacements at an academic tertiary care medical center. Disparity in device life and factors that may influence device life were analyzed. Results: The mean device life f...περισσότερα »
Comprehensive Emergency Airway Response Team (EART) Training and Education: Impact on Team Effectiveness, Personnel Confidence, and Protocol Knowledge
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Objective: To evaluate the efficacy and utility of simulation of the Emergency Airway Response Team (EART) at a tertiary care hospital to improve team dynamics and confidence and knowledge in managing an emergency airway. Methods: This was a descriptive, quantitative performance improvement study. From September 1, 2013, to December 1, 2013, 177 members of the EART from anesthesia, otolaryngology, trauma surgery, emergency medicine, ICU nursing, and respiratory therapy participated in emergency airway simulations. Team dynamics and confidence levels and knowledge of EART were a... περισσότερα »
Malleus to Stapes Bone Cement Rebridging Ossiculoplasty: Why Dont We Perform Frequently?
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Objective: To evaluate the effectiveness of malleus to stapes bone cement rebridging (MS-BCR) for Austin Kartush group A ossicular defects and compare the audiological results with incus interposition (IP) and incus to stapes bone cement rebridging (IS-BCR). Methods: Patients for whom type 2 tympanoplasty had been performed in a tertiary referral center were examined. Revision cases and those with graft failure were excluded. Three treatment groups were IS-BCR, IP, and MS-BCR. Preoperative and postoperative audiological results were compared. Results: A total of 92 patients we... περισσότερα »
High-Grade Neuroendocrine Carcinoma of the Larynx: The Mayo Clinic Experience
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Objective: To report a single institutional series of high-grade neuroendocrine carcinoma of the larynx (NCL), a very rare yet aggressive tumor. To review the management of NCL, including discussion of clinical behavior, treatment outcome, and prognosis. Method: A retrospective chart review of high-grade laryngeal neuroendocrine carcinomas at a single institution, including small- and large-cell neuroendocrine carcinomas. A total of 8 patients with high-grade NCL treated at our institution from 1992 to 2014 were identified. Results: The median age at diagnosis was 65.5 years (... περισσότερα »
Evolution of Patients With Immediate Complete Facial Paralysis Secondary to Acoustic Neuroma Surgery
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Objective: To study the evolution of patients with immediate complete facial paralysis after acoustic neuroma surgery in different scenarios and assess different facial reanimations techniques. Methods: This study included 50 patients with complete facial paralysis immediately after acoustic neuroma surgery. Data were analyzed into 4 groups according to the need and type of reconstruction of the facial nerve, either none, immediate, or on a deferred basis. All patients had intraoperative facial nerve monitoring, and facial nerve function was evaluated according the House-Brackm... περισσότερα »
Emotional Perception of Music in Children With Bimodal Fitting and Unilateral Cochlear Implant
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Objective: Biological, structural, and acoustical constraints faced by cochlear implant (CI) users can alter the perception of music. Bimodal fitting not only provides bilateral hearing but can also improve auditory skills. This study was conducted to assess the impact of this amplification style on the emotional perception of music among children with hearing loss (HL). Methods: Twenty-five children with congenital severe to profound HL and unilateral CIs, 20 children with bimodal fitting, and 30 children with normal hearing participated in this study. Their emotional perceptio... περισσότερα »
Evaluation of Autologous Fascia Implantation With Controlled Release of Fibroblast Growth Factor for Recurrent Laryngeal Nerve Paralysis Due to Long-term Denervation
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Objectives: Paralyzed tissue due to long-term denervation is resistant to many treatments because it induces irreversible histological changes and disorders of deglutition or phonation. We sought to determine the effect of autologous transplantation of fascia into the vocal fold (ATFV) with controlled release of basic fibroblast growth factor (bFGF) on long-term unilateral vocal fold paralysis (UVFP). Methods: Unilateral recurrent laryngeal nerve (RLN) section was performed on 20 rats. Five rats were implanted with autologous fascia only (fascia group), and 10 rats were implant... περισσότερα »
The Effect of Initial Tracheoesophageal Voice Prosthesis Size on Postoperative Complications and Voice Outcomes
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
Objectives: The optimal initial size of tracheoesophageal voice prosthesis (TEVP) for tracheoesophageal voice restoration (TEVR) remains unclear. As purported advantages exist favoring the placement of both 16F and 20F prostheses, this study compares complications and voicing outcomes after placement of 16 and 20 French (F) prostheses. Methods: All cases of TEVR at an academic medical center were retrospectively reviewed (2007-2013). Complications including dislodgement, leakage, infection, and granulation tissue were compared. Outcomes including frequency of prosthesis change,...περισσότερα »
Book Review: Functional Reconstructive Nasal Surgery
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
from #ORL via xlomafota13 on Inoreader http://ift.tt/1X8cvaO via IFTTT
A phase I study evaluating cixutumumab, a type 1 insulin-like growth factor receptor inhibitor, given every 2 or 3 weeks in Japanese patients with advanced solid tumors.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 54 δευτερόλεπτα
*A phase I study evaluating cixutumumab, a type 1 insulin-like growth factor receptor inhibitor, given every 2 or 3 weeks in Japanese patients with advanced solid tumors.* Cancer Chemother Pharmacol. 2016 Apr 30; Authors: Doi T, Shitara K, Kojima T, Yoshino T, Dontabhaktuni A, Rebscher H, Tang S, Cosaert J, Ohtsu A Abstract PURPOSE: The primary objective of this phase I trial was to establish the safety profile and pharmacokinetics of cixutumumab administered every 2 weeks (q2w) or every 3 weeks (q3w) in Japanese patients with advanced solid tumors. Exploratory analyses included ...περισσότερα »
In vitro development and validation of a non-invasive (13)C-stable isotope assay for ornithine decarboxylase.
Alexandros G. SfakianakisστοThe OesophagusΠριν από 56 δευτερόλεπτα
*In vitro development and validation of a non-invasive (13)C-stable isotope assay for ornithine decarboxylase.* J Breath Res. 2016;10(2):026009 Authors: Jaenisch S, Squire M, Butler R, Yazbeck R Abstract Oesophageal cancer is a significant cause of cancer related mortality, with increasing incidence worldwide. Ornithine decarboxylase (ODC) is an enzyme involved in polyamine synthesis and cellular proliferation, and ODC expression and activity has been implicated as a prognostic marker of oesophageal cancer. This study aimed to develop and optimise an in vitro (13)C-stable isotope...περισσότερα »
A UNITED CLASSIFICATION IN CARCINOMA OF THE ESOPHAGUS AND THE CARDIA BASED ON THE LYMPH METASTASIS.
Alexandros G. SfakianakisστοThe OesophagusΠριν από 56 δευτερόλεπτα
Related Articles *A UNITED CLASSIFICATION IN CARCINOMA OF THE ESOPHAGUS AND THE CARDIA BASED ON THE LYMPH METASTASIS.* Khirurgiia (Sofiia). 2015;81(3):123-34 Authors: Tsenovski Y, Tchervenyakov A Abstract The problem of the surgical treatment of cancer of the esophagus-gastric transition is up to date until today and has caused disagreements between the surgeons. This is one of the most aggressive visceral tumors. Metastasis is very specific due to the specificity of lymph edema. We operated 213 patients for four years period, 162 of them male and 51 - female. Cancer cardia and ... περισσότερα »
Buried adenocarcinoma hidden by normal squamous epithelium in Barrett's esophagus: should we enlarge the margins for endoscopic resections?
Alexandros G. SfakianakisστοThe OesophagusΠριν από 56 δευτερόλεπτα
[image: http:--http://ift.tt/1SvbKVd] Related Articles *Buried adenocarcinoma hidden by normal squamous epithelium in Barrett's esophagus: should we enlarge the margins for endoscopic resections?* Endoscopy. 2015;47 Suppl 1 UCTN:E439-41 Authors: Erard-Poinsot D, Pioche M, Chabrun E, Rivory J, Belleannee G, Hervieu V, Ponchon T PMID: 26397860 [PubMed - indexed for MEDLINE] from #Esophageal Cancer via xlomafota13 on Inoreader http://ift.tt/1ZbGihk via IFTTT
Foam plombage: a novel technique for optimal fixation of polyglycolic acid sheets positioned using "clip and pull" after esophageal endoscopic submucosal dissection.
Alexandros G. SfakianakisστοThe OesophagusΠριν από 56 δευτερόλεπτα
[image: http:--http://ift.tt/1SvbKVd] Related Articles *Foam plombage: a novel technique for optimal fixation of polyglycolic acid sheets positioned using "clip and pull" after esophageal endoscopic submucosal dissection.* Endoscopy. 2015;47 Suppl 1 UCTN:E435-6 Authors: Ono S, Sakaguchi Y, Tsuji Y, Kodashima S, Yamamichi N, Fujishiro M, Koike K PMID: 26397858 [PubMed - indexed for MEDLINE] from #Esophageal Cancer via xlomafota13 on Inoreader http://ift.tt/1Tlved2 via IFTTT
Esophagogastric junction morphology is associated with a positive impedance-pH monitoring in patients with GERD.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Esophagogastric junction morphology is associated with a positive impedance-pH monitoring in patients with GERD.* Neurogastroenterol Motil. 2015 Aug;27(8):1175-82 Authors: Tolone S, de Cassan C, de Bortoli N, Roman S, Galeazzi F, Salvador R, Marabotto E, Furnari M, Zentilin P, Marchi S, Bardini R, Sturniolo GC, Savarino V, Savarino E Abstract BACKGROUND: High-resolution manometry (HRM) provides information on esophagogastric junction (EGJ) morphology, distinguishing three different subtypes. Data on the correlati... περισσότερα »
Conversion of Nissen fundoplication to laparoscopic gastric bypass: video case report and literature review.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Conversion of Nissen fundoplication to laparoscopic gastric bypass: video case report and literature review.* Surg Obes Relat Dis. 2015 Jul-Aug;11(4):973-4 Authors: Thereaux J, Roche C, Bail JP PMID: 26003900 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1SNhvfL via IFTTT
upper respiratory tract infection; +42 new citations
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
42 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2016/05/04 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1Y7NT0e via IFTTT
Tomosynthesis in the Diagnostic Setting: Changing Rates of BI-RADS Final Assessment over Time.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Tomosynthesis in the Diagnostic Setting: Changing Rates of BI-RADS Final Assessment over Time.* Radiology. 2016 May 3;:151999 Authors: Raghu M, Durand MA, Andrejeva L, Goehler A, Michalski MH, Geisel JL, Hooley RJ, Horvath LJ, Butler R, Forman HP, Philpotts LE Abstract Purpose To evaluate the effect of tomosynthesis in diagnostic mammography on the Breast Imaging Reporting and Data System (BI-RADS) final assessment categories over time. Materials and Methods This retrospective study was approved by the institutional review board. The authors reviewed all diagnostic mammograms ob...περισσότερα »
Evaluation of the diagnostic value of 64 simultaneously measured autoantibodies for early detection of gastric cancer.
Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα
*Evaluation of the diagnostic value of 64 simultaneously measured autoantibodies for early detection of gastric cancer.* Sci Rep. 2016;6:25467 Authors: Werner S, Chen H, Butt J, Michel A, Knebel P, Holleczek B, Zörnig I, Eichmüller SB, Jäger D, Pawlita M, Waterboer T, Brenner H Abstract Autoantibodies against tumor-associated antigens (TAAs) have been suggested as biomarkers for early detection of gastric cancer. However, studies that systematically assess the diagnostic performance of a large number of autoantibodies are rare. Here, we used bead-based multiplex serology to simul...περισσότερα »
In vitro development and validation of a non-invasive (13)C-stable isotope assay for ornithine decarboxylase.
Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα
*In vitro development and validation of a non-invasive (13)C-stable isotope assay for ornithine decarboxylase.* J Breath Res. 2016;10(2):026009 Authors: Jaenisch S, Squire M, Butler R, Yazbeck R Abstract Oesophageal cancer is a significant cause of cancer related mortality, with increasing incidence worldwide. Ornithine decarboxylase (ODC) is an enzyme involved in polyamine synthesis and cellular proliferation, and ODC expression and activity has been implicated as a prognostic marker of oesophageal cancer. This study aimed to develop and optimise an in vitro (13)C-stable isotope...περισσότερα »
Low-level laser therapy for the prevention of low salivary flow rate after radiotherapy and chemotherapy in patients with head and neck cancer.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Low-level laser therapy for the prevention of low salivary flow rate after radiotherapy and chemotherapy in patients with head and neck cancer. Radiol Bras. 2016 Mar-Apr;49(2):86-91 Authors: Gonnelli FA, Palma LF, Giordani AJ, Deboni AL, Dias RS, Segreto RA, Segreto HR Abstract OBJECTIVE: To determine whether low-level laser therapy can prevent salivary hypofunction after radiotherapy […]
Gustatory Dysfunction and Decreased Number of Fungiform Taste Buds in Patients With Chronic Otitis Media With Cholesteatoma.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Gustatory Dysfunction and Decreased Number of Fungiform Taste Buds in Patients With Chronic Otitis Media With Cholesteatoma. Ann Otol Rhinol Laryngol. 2016 May 2; Authors: Saito T, Ito T, Ito Y, Yamada T, Okamoto M, Manabe Y Abstract OBJECTIVE: To compare the number of fungiform taste buds among patients with chronic otitis media (COM), those […]
Laryngeal adenocarcinoma not otherwise specified: A population-based perspective.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Laryngeal adenocarcinoma not otherwise specified: A population-based perspective. Laryngoscope. 2016 May 2; Authors: Spinazzi EF, Abboud MT, Dubal PM, Verma SP, Park RC, Baredes S, Eloy JA Abstract OBJECTIVES/HYPOTHESIS: Laryngeal adenocarcinoma not otherwise specified (LAdC NOS) is a category to which variants of minor salivary gland tumors of the larynx that do not fit other […]
The Ankle Brachial Index Exhibits Better Association of Cardiovascular Prognosis Than Non-High-Density Lipoprotein Cholesterol in Type 2 Diabetes.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The Ankle Brachial Index Exhibits Better Association of Cardiovascular Prognosis Than Non-High-Density Lipoprotein Cholesterol in Type 2 Diabetes. Am J Med Sci. 2016 May;351(5):492-498 Authors: Chang LH, Hwu CM, Chu CH, Won JG, Kwok CF, Lin HD, Chen HS, Lin YC, Lin LY Abstract OBJECTIVE: The association between ankle brachial index (ABI) and outcomes in […]
Prevalence of oral ulcers and its association with addictions in rural population of western Uttar Pradesh and eastern Rajasthan
Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 4 May 2016 *Source:*Journal of Oral Biology and Craniofacial Research Author(s): Santanu Chaudhuri, Somnath Dey, Ram Chandra Bajpai BackgroundHead and neck cancer in Indian perspective predominantly relates to tobacco use. The present study explores the prevalence of oral ulcers and its association with addictions among the population of Uttar Pradesh and Rajasthan, India.MethodologyThe screening method in early detection of head and neck cancer is broadly symptom based. 1399 subjects from Uttar Pradesh and Rajasthan were screened by trained personnel... περισσότερα »
Myeloperoxidase-Antineutrophil Cytoplasmic Antibody-Positive Otitis Media and Rhinosinusitis With Pathological Features of Immunoglobulin G4-Related Disease: A Case Report
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Background: Immunoglobulin G4-related disease (IgG4-RD) and antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) have different clinical and pathological features. However, differentiation between these 2 disorders is sometimes difficult. Objective: To report a case involving a patient with characteristics of both IgG4-RD and AAV. Methods: Case report with literature review. Results: We report a case of myeloperoxidase-ANCA–positive otitis media and rhinosinusitis with pathological features of IgG4-RD in a 73-year-old man. The patient was first clinically s... περισσότερα »
Glottic Cancer: A Metamorphosing Disease
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Objective: Conventional wisdom is that the overwhelming majority of glottic cancer patients have a smoking history. However, in recent years observations suggested that an increasing number of glottic cancer patients had never been smokers. Therefore, an investigation was done examining the incidence of having a smoking history in a recent cohort of glottic cancer patients. Method: Retrospective review of 100 patients with glottic cancer to determine those reporting never having smoked. Results: Thirty-one of 100 did not have a smoking history. Clinical observations of those c... περισσότερα »
Reply to the Letter to Editor by Maeda et al.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Reply to the Letter to Editor by Maeda et al.* J Am Med Dir Assoc. 2015 Oct 1;16(10):897 Authors: Lee JS, Kwok T PMID: 26433863 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1SNhwR1 via IFTTT
Injection laryngoplasty in children with cystic fibrosis and abnormal swallow.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Injection laryngoplasty in children with cystic fibrosis and abnormal swallow.* Int J Pediatr Otorhinolaryngol. 2015 Nov;79(11):1856-9 Authors: Virbalas J, McMullen C, Cheng J Abstract OBJECTIVE: Children with cystic fibrosis (CF) are uniquely vulnerable to the pulmonary complications of chronic aspiration. We present a case series of children with CF and evidence of chronic aspiration who underwent injection laryngoplasty to improve the safety and efficacy of their swallow. STUDY DESIGN: Retrospective chart revie... περισσότερα »
Angiotensin-Converting Enzyme Inhibitor in Tube-Fed Patients With Stroke History.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Angiotensin-Converting Enzyme Inhibitor in Tube-Fed Patients With Stroke History.* J Am Med Dir Assoc. 2015 Oct 1;16(10):896-7 Authors: Maeda K, Wakabayashi H, Shamoto H PMID: 26297619 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1W71wyS via IFTTT
Peroral endoscopic myotomy for esophageal muscular ring.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--http://ift.tt/1SvbKVd] Related Articles *Peroral endoscopic myotomy for esophageal muscular ring.* Endoscopy. 2015;47 Suppl 1 UCTN:E387-8 Authors: Song GW, Ko WJ, Kim WH, Hahm KB, Hong SP, Cho JY PMID: 26273774 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1SNhwQQ via IFTTT
Esophageal hematoma after peroral endoscopic myotomy for achalasia in a patient on antiplatelet therapy.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--http://ift.tt/1SvbKVd] Related Articles *Esophageal hematoma after peroral endoscopic myotomy for achalasia in a patient on antiplatelet therapy.* Endoscopy. 2015;47 Suppl 1 UCTN:E363-4 Authors: Benech N, Pioche M, O'Brien M, Rivory J, Roman S, Mion F, Ponchon T PMID: 26262447 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/26SDM5m via IFTTT
Central Nervous System Control of Voice and Swallowing.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Central Nervous System Control of Voice and Swallowing.* J Clin Neurophysiol. 2015 Aug;32(4):294-303 Authors: Ludlow CL Abstract This review of the central nervous control systems for voice and swallowing has suggested that the traditional concepts of a separation between cortical and limbic and brain stem control should be refined and be more integrative. For voice production, a separation of the nonhuman vocalization system from the human learned voice production system has been posited based primarily on studi... περισσότερα »
Dysphonia and Dysphagia: Electrophysiological Techniques From the Laboratory to the Clinical Practice.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Dysphonia and Dysphagia: Electrophysiological Techniques From the Laboratory to the Clinical Practice.* J Clin Neurophysiol. 2015 Aug;32(4):273 Authors: Kimaid PA PMID: 26241235 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1SNhvwm via IFTTT
Hypnotherapy for Esophageal Disorders.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Hypnotherapy for Esophageal Disorders.* Am J Clin Hypn. 2015 Jul;58(1):22-33 Authors: Riehl ME, Keefer L Abstract Hypnotherapy is an evidence based intervention for the treatment of functional bowel disorders, particularly irritable bowel syndrome. While similar in pathophysiology, less is known about the utility of hypnotherapy in the upper gastrointestinal tract. Esophageal disorders, most of which are functional in nature, cause painful and uncomfortable symptoms that impact patient ... περισσότερα »
Detecting laryngopharyngeal reflux in patients with upper airways symptoms: Symptoms, signs or salivary pepsin?
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Detecting laryngopharyngeal reflux in patients with upper airways symptoms: Symptoms, signs or salivary pepsin?* Respir Med. 2015 Aug;109(8):963-9 Authors: Spyridoulias A, Lillie S, Vyas A, Fowler SJ Abstract BACKGROUND: Laryngopharyngeal reflux (LPR) can induce laryngeal hyper-responsiveness, a unifying feature underlying chronic cough and vocal cord dysfunction. The diagnosis of LPR currently relies on invasive oesophageal pH impedance testing. We compared symptoms, laryngeal signs and salivary pepsin as potent... περισσότερα »
Inter-rater reliability and validity of automated impedance manometry analysis and fluoroscopy in dysphagic patients after head and neck cancer radiotherapy.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Inter-rater reliability and validity of automated impedance manometry analysis and fluoroscopy in dysphagic patients after head and neck cancer radiotherapy.* Neurogastroenterol Motil. 2015 Aug;27(8):1183-9 Authors: Szczesniak MM, Maclean J, Zhang T, Liu R, Cock C, Rommel N, Omari TI, Cook IJ Abstract BACKGROUND: Pharyngeal automated impedance manometry (AIM) analysis is a novel non-radiological method to analyze swallowing function based on impedance-pressure recordings. In dysphagic head and neck cancer patient... περισσότερα »
Esophagogastric junction morphology is associated with a positive impedance-pH monitoring in patients with GERD.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Esophagogastric junction morphology is associated with a positive impedance-pH monitoring in patients with GERD.* Neurogastroenterol Motil. 2015 Aug;27(8):1175-82 Authors: Tolone S, de Cassan C, de Bortoli N, Roman S, Galeazzi F, Salvador R, Marabotto E, Furnari M, Zentilin P, Marchi S, Bardini R, Sturniolo GC, Savarino V, Savarino E Abstract BACKGROUND: High-resolution manometry (HRM) provides information on esophagogastric junction (EGJ) morphology, distinguishing three different subtypes. Data on the correlati... περισσότερα »
Conversion of Nissen fundoplication to laparoscopic gastric bypass: video case report and literature review.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Conversion of Nissen fundoplication to laparoscopic gastric bypass: video case report and literature review.* Surg Obes Relat Dis. 2015 Jul-Aug;11(4):973-4 Authors: Thereaux J, Roche C, Bail JP PMID: 26003900 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1SNhvfL via IFTTT
Application of simple swallowing provocation test with fiberoptic endoscopic evaluation of swallowing in a cross-sectional study.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Application of simple swallowing provocation test with fiberoptic endoscopic evaluation of swallowing in a cross-sectional study.* BMC Geriatr. 2015;15:48 Authors: Tejima C, Kikutani T, Takahashi N, Tamura F, Yoshida M Abstract BACKGROUND: This study aimed to develop a simultaneously swallowing provocation test for dysphagia patients undergoing fiberoptic endoscopic evaluation of swallowing (FEES), as well as to evaluate its efficacy. METHODS: In this test, 0·4 and 2·0 mL volumes of water... περισσότερα »
Electrical stimulation based evaluation for functional modification of renal autonomic nerve activities induced by catheter ablation.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Electrical stimulation based evaluation for functional modification of renal autonomic nerve activities induced by catheter ablation.* Heart Rhythm. 2016 Apr 29; Authors: Chinushi M, Suzuki K, Saitoh O, Furushima H, Iijima K, Izumi D, Sato A, Sugai M, Iwafuchi M Abstract BACKGROUND: Catheter ablation of the renal artery can be performed without apparent angiographic stenosis. This suggests that renal nerve function can be attenuated with minor structural damage to the renal artery. OBJECTIVE: To clarify this hypothesis, we examined the relationship between electrical nerve stimul... περισσότερα »
Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Beyond multiple mechanisms and a unique drug: Defective autophagy as pivotal player in cerebral cavernous malformation pathogenesis and implications for targeted therapies.* Rare Dis. 2016;4(1):e1142640 Authors: Marchi S, Trapani E, Corricelli M, Goitre L, Pinton P, Retta SF Abstract Cerebral Cavernous Malformation (CCM) is a major cerebrovascular disease of proven genetic origin affecting 0.3-0.5% of the general population. It is characterized by abnormally enlarged and leaky capillaries, which predispose to seizures, focal neurological deficits and intracerebral hemorrhage. Ca... περισσότερα »
Long noncoding RNAs in kidney and cardiovascular diseases.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Long noncoding RNAs in kidney and cardiovascular diseases.* Nat Rev Nephrol. 2016 May 3; Authors: Lorenzen JM, Thum T Abstract Transcription of a large part of the human genome results in RNA transcripts that have limited or no protein-coding potential. These include long noncoding RNAs (lncRNAs), which are defined as being ≥200 nucleotides long. Unlike microRNAs, which have been extensively studied, little is known about the functional role of lncRNAs. However, studies over the past 5 years have shown that lncRNAs interfere with tissue homeostasis and have a role in pathologica... περισσότερα »
Systemic lupus erythematosus: Defective noncanonical autophagy in SLE-like disease.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Systemic lupus erythematosus: Defective noncanonical autophagy in SLE-like disease.* Nat Rev Nephrol. 2016 May 3; Authors: Allison SJ PMID: 27140848 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1NVgSUJ via IFTTT
Cellular, structural and functional cardiac remodelling following pressure overload and unloading.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Cellular, structural and functional cardiac remodelling following pressure overload and unloading.* Int J Cardiol. 2016 Apr 23;216:32-42 Authors: Dadson K, Kovacevic V, Rengasamy P, Kim GH, Boo S, Li RK, George I, Schulze PC, Hinz B, Sweeney G Abstract BACKGROUND: The cardiac remodelling process in advanced heart failure due to pressure overload has not been clearly defined but likely involves mechanisms of cardiac fibrosis and cardiomyocyte hypertrophy. The aim of this study was to examine pressure overload (PO)-induced cardiac remodelling processes and their reversibility afte...περισσότερα »
Inhibition of excessive oxidative protein folding is protective in MPP+ toxicity-induced PD models.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Inhibition of excessive oxidative protein folding is protective in MPP+ toxicity-induced PD models.* Antioxid Redox Signal. 2016 May 2; Authors: Lehtonen S, Jaronen M, Vehviläinen P, Lakso M, Rudgalvyte M, Keksa-Goldsteine V, Wong G, Courtney M, Koistinaho J, Goldsteins G Abstract AIMS: Protein misfolding occurs in neurodegenerative diseases including Parkinson's disease (PD). In endoplasmic reticulum (ER) an overload of misfolded proteins, particularly alpha-synuclein (αSyn) in PD, may cause stress and activate the unfolded protein response (UPR). This UPR includes activation o...περισσότερα »
Cardioprotective effect of Salvianolic acid B on acute myocardial infarction by promoting autophagy and neovascularization and inhibiting apoptosis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Cardioprotective effect of Salvianolic acid B on acute myocardial infarction by promoting autophagy and neovascularization and inhibiting apoptosis.* J Pharm Pharmacol. 2016 May 3; Authors: Lin C, Liu Z, Lu Y, Yao Y, Zhang Y, Ma Z, Kuai M, Sun X, Sun S, Jing Y, Yu L, Li Y, Zhang Q, Bian H Abstract OBJECTIVES: The aim of this study was to investigate the cardioprotective effect of salvianolic acid B (Sal B) on acute myocardial infarction (AMI) in rats and its potential mechanisms. METHODS: The AMI model was established in rats to study the effect of Sal B on AMI. Haematoxylin-eos...περισσότερα »
Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Intraneuronal aggregation of the β-CTF fragment of APP (C99) induces Aβ-independent lysosomal-autophagic pathology.* Acta Neuropathol. 2016 Apr 30; Authors: Lauritzen I, Pardossi-Piquard R, Bourgeois A, Pagnotta S, Biferi MG, Barkats M, Lacor P, Klein W, Bauer C, Checler F Abstract Endosomal-autophagic-lysosomal (EAL) dysfunction is an early and prominent neuropathological feature of Alzheimers's disease, yet the exact molecular mechanisms contributing to this pathology remain undefined. By combined biochemical, immunohistochemical and ultrastructural approaches, we demonstrate ... περισσότερα »
HO-1 Protects against Hypoxia/Reoxygenation-Induced Mitochondrial Dysfunction in H9c2 Cardiomyocytes.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*HO-1 Protects against Hypoxia/Reoxygenation-Induced Mitochondrial Dysfunction in H9c2 Cardiomyocytes.* PLoS One. 2016;11(5):e0153587 Authors: Chen D, Jin Z, Zhang J, Jiang L, Chen K, He X, Song Y, Ke J, Wang Y Abstract BACKGROUND: Mitochondrial dysfunction would ultimately lead to myocardial cell apoptosis and death during ischemia-reperfusion injuries. Autophagy could ameliorate mitochondrial dysfunction by autophagosome forming, which is a catabolic process to preserve the mitochondrial's structural and functional integrity. HO-1 induction and expression are important protecti... περισσότερα »
Autophagy is involved in regulating VEGF during high-glucose-induced podocyte injury.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Autophagy is involved in regulating VEGF during high-glucose-induced podocyte injury.* Mol Biosyst. 2016 May 3; Authors: Miaomiao W, Chunhua L, Xiaochen Z, Xiaoniao C, Hongli L, Zhuo Y Abstract Podocytes are the major sites of vascular endothelial growth factor (VEGF) production in kidneys. Over-expression of VEGF is involved in the pathogenesis of diabetic nephropathy (DN), and an emerging body of evidence suggests that autophagy plays an important role in DN. In this study, the effect of autophagy on over-expressed VEGF along with its underlying mechanism was investigated in s... περισσότερα »
Autophagy Induction in Tobacco Leaves Infected by Potato Virus Y(O) and Its Putative Roles.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Autophagy Induction in Tobacco Leaves Infected by Potato Virus Y(O) and Its Putative Roles.* Biochem Biophys Res Commun. 2016 Apr 29; Authors: Choi D, Park J, Oh S, Cheong H Abstract Autophagy plays a critical role in the innate immune response of plants to pathogen infection. In the present study, we examined autophagy induced by potato virus Y ordinary strain (PVY(O)) infection in tobacco (Nicotiana benthamiana). Enzyme-linked immunosorbent assays revealed that the number of virus particles in the plant peaked at 2 weeks post-inoculation and then gradually decreased. Additiona...περισσότερα »
[Antitumoral functions of autophagy inhibition in colorectal cancer: the intestinal microbiota and the immune system come to the rescue…].
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*[Antitumoral functions of autophagy inhibition in colorectal cancer: the intestinal microbiota and the immune system come to the rescue…].* Med Sci (Paris). 2016 Apr;32(4):339-342 Authors: Lévy J, Romagnolo B PMID: 27137689 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1SNeufy via IFTTT
AMP-activated kinase α2 deficiency protects mice from denervation-induced skeletal muscle atrophy.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*AMP-activated kinase α2 deficiency protects mice from denervation-induced skeletal muscle atrophy.* Arch Biochem Biophys. 2016 Apr 29; Authors: Guo Y, Jin M, Tang Y, Wang T, Wei B, Feng R, Gong B, Wang H, Ji G, Lu Z Abstract AMP-activated protein kinase (AMPK) is a master regulator of skeletal muscle metabolic pathways. Recently, AMPK activation by AICAR has been shown to increase myofibrillar protein degradation in C2C12 myotubes via stimulating autophagy and ubiquitin proteasome system. However, the impact of AMPKα on denervation induced muscle atrophy has not been tested. In ... περισσότερα »
A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1Iu32Gt] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *A Systems Approach Identifies Essential FOXO3 Functions at Key Steps of Terminal Erythropoiesis.* PLoS Genet. 2015 Oct;11(10):e1005526 Authors: Liang R, Campreciós G, Kou Y, McGrath K, Nowak R, Catherman S, Bigarella CL, Rimmelé P, Zhang X, Gnanapragasam MN, Bieker JJ, Papatsenko D, Ma'ayan A, Bresnick E, Fowler V, Palis J, Ghaffari S Abstract Circulating red blood cells (RBCs) are essential for tissue oxygenation and homeostasis. Defective terminal erythropoiesis contributes to decrease... περισσότερα »
BAG3: a new player in the heart failure paradigm.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *BAG3: a new player in the heart failure paradigm.* Heart Fail Rev. 2015 Jul;20(4):423-34 Authors: Knezevic T, Myers VD, Gordon J, Tilley DG, Sharp TE, Wang J, Khalili K, Cheung JY, Feldman AM Abstract BAG3 is a cellular protein that is expressed predominantly in skeletal and cardiac muscle but can also be found in the brain and in the peripheral nervous system. BAG3 functions in the cell include: serving as a co-chaperone with members of the heat-shock protein family of prote... περισσότερα »
Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--pubs.acs.org-images-pubmed-acspub] Related Articles *Synthesis, stereochemical analysis, and derivatization of myricanol provide new probes that promote autophagic tau clearance.* ACS Chem Biol. 2015 Apr 17;10(4):1099-109 Authors: Martin MD, Calcul L, Smith C, Jinwal UK, Fontaine SN, Darling A, Seeley K, Wojtas L, Narayan M, Gestwicki JE, Smith GR, Reitz AB, Baker BJ, Dickey CA Abstract We previously discovered that one specific scalemic preparation of myricanol (1), a constituent of Myrica cerifera (bayberry/southern wax myrtle) root bark, could lower the levels o... περισσότερα »
Non-18F-FDG PET/CT in the management of patients affected by HNC: state-of-the-art.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Non-18F-FDG PET/CT in the management of patients affected by HNC: state-of-the-art.* Nucl Med Commun. 2016 May 2; Authors: Quartuccio N, Caobelli F, Di Mauro F, Cammaroto G, Young AIMN Working Group Abstract PET/computed tomography with F-fluorodeoxyglucose is considered a powerful molecular imaging technique that can provide useful information in the management of patients affected by head and neck cancer. However, misleading findings have been reported because of nonspecific uptake caused by peritumoural inflammation and physiologic changes in nonmalignant tissues in the head... περισσότερα »
Drug interactions between buprenorphine, methadone and hepatitis C therapeutics.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Drug interactions between buprenorphine, methadone and hepatitis C therapeutics.* Expert Opin Drug Metab Toxicol. 2016 May 3; Authors: Ogbuagu O, Friedland G, Bruce RD Abstract INTRODUCTION: People who inject drugs (PWID) and other individuals with opioid use disorders have a dramatically higher prevalence of hepatitis C virus (HCV) infection than the general population. The availability of novel direct acting antivirals (DAAs) for the treatment of HCV infection with very high efficacy, improved tolerability and shortened treatment durations have led to global efforts to ramp up... περισσότερα »
Child Readers’ Eye Movements in Reading Thai.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Child Readers’ Eye Movements in Reading Thai. Vision Res. 2016 Apr 29; Authors: Kasisopa B, Reilly RG, Luksaneeyanawin S, Burnham D Abstract It has recently been found that adult native readers of Thai, an alphabetic scriptio continua language, engage similar oculomotor patterns as readers of languages written with spaces between words; despite the lack of […]
Cortical encoding and neurophysiological tracking of intensity and pitch cues signaling English stress patterns in native and nonnative speakers.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Cortical encoding and neurophysiological tracking of intensity and pitch cues signaling English stress patterns in native and nonnative speakers. Brain Lang. 2016 Apr 30;155-156:49-57 Authors: Chung WL, Bidelman GM Abstract We examined cross-language differences in neural encoding and tracking of intensity and pitch cues signaling English stress patterns. Auditory mismatch negativities (MMNs) were recorded in […]
The impact of thought disorder on therapeutic alliance and personal recovery in schizophrenia and schizoaffective disorder: An exploratory study.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The impact of thought disorder on therapeutic alliance and personal recovery in schizophrenia and schizoaffective disorder: An exploratory study. Psychiatry Res. 2016 May 30;239:92-98 Authors: Cavelti M, Homan P, Vauth R Abstract Thought and language disorders are a main feature of schizophrenia. The aim of the study is to explore the impact of thought disorder […]
Giving patients a voice when they need one most.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Related Articles Giving patients a voice when they need one most. Hosp Health Netw. 2016 Feb;90(2):19 Authors: Arcuri L PMID: 27017816 [PubMed – indexed for MEDLINE] from Speech via xlomafota13 on Inoreader http://ift.tt/21QSZi0 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/26SBd3o via IFTTT
Short-term and long-term test-retest reliability of the Nasality Severity Index 2.0
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 3 May 2016 Source:Journal of Communication Disorders Author(s): Kim Bettens, Floris L. Wuyts, Evelien D’haeseleer, Anke Luyten, Iris Meerschman, Carole Van Crayelynghe, Kristiane M. Van Lierde PurposeThe Nasality Severity Index 2.0 (NSI 2.0) forms a new, multiparametric approach in the assessment of hypernasality. To enable clinical implementation of this index, the […]
Cortical encoding and neurophysiological tracking of intensity and pitch cues signaling English stress patterns in native and nonnative speakers.
Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
*Cortical encoding and neurophysiological tracking of intensity and pitch cues signaling English stress patterns in native and nonnative speakers.* Brain Lang. 2016 Apr 30;155-156:49-57 Authors: Chung WL, Bidelman GM Abstract We examined cross-language differences in neural encoding and tracking of intensity and pitch cues signaling English stress patterns. Auditory mismatch negativities (MMNs) were recorded in English and Mandarin listeners in response to contrastive English pseudowords whose primary stress occurred either on the first or second syllable (i.e., "nocTICity" vs. "... περισσότερα »
The impact of thought disorder on therapeutic alliance and personal recovery in schizophrenia and schizoaffective disorder: An exploratory study.
Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
*The impact of thought disorder on therapeutic alliance and personal recovery in schizophrenia and schizoaffective disorder: An exploratory study.* Psychiatry Res. 2016 May 30;239:92-98 Authors: Cavelti M, Homan P, Vauth R Abstract Thought and language disorders are a main feature of schizophrenia. The aim of the study is to explore the impact of thought disorder on therapeutic alliance and personal recovery because of its interference with verbal communication. Thought disorder, positive and negative symptoms (Positive and Negative Syndrome Scale), functioning (Modified Global A...περισσότερα »
Child Readers' Eye Movements in Reading Thai.
Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
*Child Readers' Eye Movements in Reading Thai.* Vision Res. 2016 Apr 29; Authors: Kasisopa B, Reilly RG, Luksaneeyanawin S, Burnham D Abstract It has recently been found that adult native readers of Thai, an alphabetic scriptio continua language, engage similar oculomotor patterns as readers of languages written with spaces between words; despite the lack of inter-word spaces, first and last characters of a word appear to guide optimal placement of Thai readers' eye movements, just to the left of word-centre. The issue addressed by the research described here is whether eye movem...περισσότερα »
Giving patients a voice when they need one most.
Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
Related Articles *Giving patients a voice when they need one most.* Hosp Health Netw. 2016 Feb;90(2):19 Authors: Arcuri L PMID: 27017816 [PubMed - indexed for MEDLINE] from Speech via xlomafota13 on Inoreader http://ift.tt/21QSZi0
Short-term and long-term test-retest reliability of the Nasality Severity Index 2.0
Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
Publication date: Available online 3 May 2016 *Source:*Journal of Communication Disorders Author(s): Kim Bettens, Floris L. Wuyts, Evelien D’haeseleer, Anke Luyten, Iris Meerschman, Carole Van Crayelynghe, Kristiane M. Van Lierde PurposeThe Nasality Severity Index 2.0 (NSI 2.0) forms a new, multiparametric approach in the assessment of hypernasality. To enable clinical implementation of this index, the short- and long-term test-retest reliability of this index was explored.MethodsIn 40 normal-speaking adults (mean age 32y, SD 11, 18-56y) and 29 normalspeaking children (mean age 8y, SD... περισσότερα »
The effect of concurrent esophageal pathology on bariatric surgical planning.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *The effect of concurrent esophageal pathology on bariatric surgical planning.* J Gastrointest Surg. 2015 Jan;19(1):111-5; discussion 115-6 Authors: Bradley DD, Louie BE, Chen J, Aye RW, McMahon R, Farivar AS Abstract In the presence of esophageal pathology, there is risk of worse outcomes after laparoscopic adjustable gastric banding (LAGB) and sleeve gastrectomy (SG). This study reviewed how an esophageal workup affected a bariatric operative plan in patients with concurrent esophageal pathology. We retrospectiv...περισσότερα »
Peroral endoscopic myotomy (POEM) for esophageal primary motility disorders: analysis of 100 consecutive patients.
Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *Peroral endoscopic myotomy (POEM) for esophageal primary motility disorders: analysis of 100 consecutive patients.* J Gastrointest Surg. 2015 Jan;19(1):161-70; discussion 170 Authors: Sharata AM, Dunst CM, Pescarus R, Shlomovitz E, Wille AJ, Reavis KM, Swanström LL Abstract INTRODUCTION: Peroral endoscopic myotomy (POEM) is a flexible endoscopic approach to the lower esophageal sphincter (LES) providing access for a myotomy to relieve dysphagia. The technique has been adopted worldwide due to reports of excellent... περισσότερα »
“Nuts and Bolts” of Laboratory Evaluation of Angioedema
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Angioedema, as a distinct disease entity, often becomes a clinical challenge for physicians, because it may cause a life-threatening condition, whereas prompt and accurate laboratory diagnostics may not be available. Although the bedside diagnosis needs to be established based on clinical symptoms and signs, family history, and the therapeutic response, later, laboratory tests are available. Currently, only for five out of the nine different types of angioedema can be diagnosed by laboratory testing, and these occur only in a minority of the patient population. Hereditary ... περισσότερα »
Prevalence of oral ulcers and its association with addictions in rural population of western Uttar Pradesh and eastern Rajasthan
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 4 May 2016 *Source:*Journal of Oral Biology and Craniofacial Research Author(s): Santanu Chaudhuri, Somnath Dey, Ram Chandra Bajpai BackgroundHead and neck cancer in Indian perspective predominantly relates to tobacco use. The present study explores the prevalence of oral ulcers and its association with addictions among the population of Uttar Pradesh and Rajasthan, India.MethodologyThe screening method in early detection of head and neck cancer is broadly symptom based. 1399 subjects from Uttar Pradesh and Rajasthan were screened by trained personn... περισσότερα »
A phase I study evaluating cixutumumab, a type 1 insulin-like growth factor receptor inhibitor, given every 2 or 3 weeks in Japanese patients with advanced solid tumors.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*A phase I study evaluating cixutumumab, a type 1 insulin-like growth factor receptor inhibitor, given every 2 or 3 weeks in Japanese patients with advanced solid tumors.* Cancer Chemother Pharmacol. 2016 Apr 30; Authors: Doi T, Shitara K, Kojima T, Yoshino T, Dontabhaktuni A, Rebscher H, Tang S, Cosaert J, Ohtsu A Abstract PURPOSE: The primary objective of this phase I trial was to establish the safety profile and pharmacokinetics of cixutumumab administered every 2 weeks (q2w) or every 3 weeks (q3w) in Japanese patients with advanced solid tumors. Exploratory analyses included ...περισσότερα »
Treatment of Radiation-Induced Oral Mucositis Using a Novel Accepted Taste of Prolonged Release Mucoadhesive Bi-medicated Double-Layer Buccal Films.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Treatment of Radiation-Induced Oral Mucositis Using a Novel Accepted Taste of Prolonged Release Mucoadhesive Bi-medicated Double-Layer Buccal Films.* AAPS PharmSciTech. 2016 May 2; Authors: Abo Enin HA, El Nabarawy NA, Elmonem RA Abstract The aim of this study was to develop a novel double-layer bi-medicated prolonged release mucoadhesive buccal film (MBF) containing lidocaine hydrochloride (LC) and diclofenac potassium (DK). The ultimate goal of the prepared system is the treatment of radiation-induced oral mucositis pain with improved patient acceptance. MBFs were prepared usin... περισσότερα »
Anti-angiogenic agents in ovarian cancer: past, present, and future.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Anti-angiogenic agents in ovarian cancer: past, present, and future.* Ann Oncol. 2016 Apr;27(suppl 1):i33-i39 Authors: Monk BJ, Minion LE, Coleman RL Abstract Angiogenesis plays a pivotal role in normal ovarian physiology as well as in the progression of ovarian cancer through ascites formation and metastatic spread. Bevacizumab (Avastin(®), Genentech; South San Francisco, CA, USA), a humanized anti-vascular endothelial growth factor (VEGF) monoclonal antibody, is the most widely studied anti-angiogenesis agent both across tumor types and specifically in epithelial ovarian cancer...περισσότερα »
FGFR-Dependent and -Independent Paracrine Signaling by Sunitinib-Resistant RCC.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*FGFR-Dependent and -Independent Paracrine Signaling by Sunitinib-Resistant RCC.* Mol Cell Biol. 2016 May 2; Authors: Tran TA, Leong HS, Pavia-Jimenez A, Fedyshyn S, Yang J, Kucejova B, Sivanand S, Spence P, Xie XJ, Peña-Llopis S, Power N, Brugarolas J Abstract Antiangiogenic therapies, such as sunitinib, have revolutionized renal cell carcinoma (RCC) treatment. However, a precarious understanding of how resistance emerges, and a lack of tractable experimental systems hinders progress. We evaluated the potential of primary RCC cultures (derived from tumors and tumorgrafts) to sig...περισσότερα »
A phase I study evaluating cixutumumab, a type 1 insulin-like growth factor receptor inhibitor, given every 2 or 3 weeks in Japanese patients with advanced solid tumors.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*A phase I study evaluating cixutumumab, a type 1 insulin-like growth factor receptor inhibitor, given every 2 or 3 weeks in Japanese patients with advanced solid tumors.* Cancer Chemother Pharmacol. 2016 Apr 30; Authors: Doi T, Shitara K, Kojima T, Yoshino T, Dontabhaktuni A, Rebscher H, Tang S, Cosaert J, Ohtsu A Abstract PURPOSE: The primary objective of this phase I trial was to establish the safety profile and pharmacokinetics of cixutumumab administered every 2 weeks (q2w) or every 3 weeks (q3w) in Japanese patients with advanced solid tumors. Exploratory analyses included ...περισσότερα »
Treatment of Radiation-Induced Oral Mucositis Using a Novel Accepted Taste of Prolonged Release Mucoadhesive Bi-medicated Double-Layer Buccal Films.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Treatment of Radiation-Induced Oral Mucositis Using a Novel Accepted Taste of Prolonged Release Mucoadhesive Bi-medicated Double-Layer Buccal Films.* AAPS PharmSciTech. 2016 May 2; Authors: Abo Enin HA, El Nabarawy NA, Elmonem RA Abstract The aim of this study was to develop a novel double-layer bi-medicated prolonged release mucoadhesive buccal film (MBF) containing lidocaine hydrochloride (LC) and diclofenac potassium (DK). The ultimate goal of the prepared system is the treatment of radiation-induced oral mucositis pain with improved patient acceptance. MBFs were prepared usin... περισσότερα »
Toxic epidermal necrolysis in patient with malignant astrocytoma.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Toxic epidermal necrolysis in patient with malignant astrocytoma.* Pol Merkur Lekarski. 2016 Jan;40(235):25-7 Authors: Kaczmarska-Turek D, Bartnik P, Kacperczyk J, Orlewski J, Olszewska M, Krasnodębska-Kiljańska M Abstract UNLABELLED: Toxic epidermal necrolysis (TEN) is a severe, life-threatening mucocutaneus adverse reaction, most commonly triggered by medication. Treatment in some aspects is still controversial. CASE REPORT: Patient with malignant astrocytoma, treated with palliative radiotherapy, developed massive erythema with bullae. Patient suffered from t... περισσότερα »
FLIGHT ASSOCIATED DISSECTION.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*FLIGHT ASSOCIATED DISSECTION.* J La State Med Soc. 2015 May-Jun;167(3):151-152 Authors: Varnado Md W, Thibodaux Md R Abstract INTRODUCTION: "Economy Class Stroke "is a term recognized in the literature pertaining to paradoxical strokes of patent foramen ovale. However, other central nervous system (CNS) processes should be considered with long distance fights. We present two cases of vascular dissection associated with long distance flights. Case 1: A 25-year-old man recently on an economy class plane flight from Brazil acknowledged being uncomfortable during the flight. Several... περισσότερα »
A RARE MULTISYSTEMIC DISEASE WITH AUTOIMMUNE ETIOLOGY.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*A RARE MULTISYSTEMIC DISEASE WITH AUTOIMMUNE ETIOLOGY.* J La State Med Soc. 2015 May-Jun;167(3):147-148 Authors: Saad Md S, Pumarol Md E Abstract INTRODUCTION: Voght Koyonagi Harada syndrome (VKH) is a rare systemic disorder involving many organ systems. VKH results from T-cell mediated autoimmune reaction against melanocyte antigens in genetically predisposed patients. CASE: A 23-year-old woman presented to the internal medicine clinic complaining of distorted vision, bilateral eye pain, headaches, tinnitus, hyperacusis and fatigue for three weeks. She also complained of general... περισσότερα »
Mechanobiology of the tooth movement during the orthodontic treatment: a literature review.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Mechanobiology of the tooth movement during the orthodontic treatment: a literature review.* Minerva Stomatol. 2016 Mar 17; Authors: Isola G, Matarese G, Cordasco G, Perillo L, Ramaglia L Abstract Orthodontic tooth movement differs significantly from the physiological tooth movement, because it effects a biological response of the surrounding tissues of the teeth, resulting in a remodeling of the periodontal ligament and the alveolar bone. The result is a biochemical adaptive response to the application of the orthodontic force with the reorganization of the intracellular and th... περισσότερα »
Effect of different mixing methods on the bacterial microleakage of calcium-enriched mixture cement.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Effect of different mixing methods on the bacterial microleakage of calcium-enriched mixture cement.* Minerva Stomatol. 2016 Mar 17; Authors: Shahi S, Jeddi Khajeh S, Rahimi S, Yavari HR, Jafari F, Samiei M, Ghasemi N, Salem Milani A Abstract BACKGROUND: Calcium-Enriched Mixture Cement is used in the field of endodontics. It is similar to Mineral Trioxide Aggregate in its main ingredients.The present study investigated the effect of different mixing methods on the bacterial microleakage of CEM cement. METHODS: A total of 55 human single-rooted human permanent teeth were decorona... περισσότερα »
microRNAs: Key Players in Hematopoiesis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *microRNAs: Key Players in Hematopoiesis.* Adv Exp Med Biol. 2015;887:171-211 Authors: Raghuwanshi S, Karnati HK, Sarvothaman S, Gutti U, Saladi RG, Tummala PR, Gutti RK Abstract microRNAs (miRNAs) are small length noncoding RNAs which play a key role in cellular processes such as proliferation, differentiation, and development of lineage hematopoietic cells and matured blood cells. Aberrant expression of miRNAs has been reported in several hematopoietic disorders. The involvement of miRNAs in regulation of variou... περισσότερα »
A phase 2 study of idelalisib plus rituximab in treatment-naïve older patients with chronic lymphocytic leukemia.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *A phase 2 study of idelalisib plus rituximab in treatment-naïve older patients with chronic lymphocytic leukemia.* Blood. 2015 Dec 17;126(25):2686-94 Authors: O'Brien SM, Lamanna N, Kipps TJ, Flinn I, Zelenetz AD, Burger JA, Keating M, Mitra S, Holes L, Yu AS, Johnson DM, Miller LL, Kim Y, Dansey RD, Dubowy RL, Coutre SE Abstract Idelalisib is a first-in-class oral inhibitor of PI3Kδ that has shown substantial activity in patients with relapsed/refractory chronic lymphocytic... περισσότερα »
Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemia.* Blood. 2015 Dec 17;126(25):2676-85 Authors: Sanjuan-Pla A, Bueno C, Prieto C, Acha P, Stam RW, Marschalek R, Menéndez P Abstract Infant B-cell acute lymphoblastic leukemia (B-ALL) accounts for 10% of childhood ALL. The genetic hallmark of most infant B-ALL is chromosomal rearrangements of the mixed-lineage leukemia (MLL) gene. Despite improvement in the clinical management and survival (∼... περισσότερα »
Memory B-cell reconstitution following allogeneic hematopoietic stem cell transplantation is an EBV-associated transformation event.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Memory B-cell reconstitution following allogeneic hematopoietic stem cell transplantation is an EBV-associated transformation event.* Blood. 2015 Dec 17;126(25):2665-75 Authors: Burns DM, Tierney R, Shannon-Lowe C, Croudace J, Inman C, Abbotts B, Nagra S, Fox CP, Chaganti S, Craddock CF, Moss P, Rickinson AB, Rowe M, Bell AI Abstract Allogeneic stem cell transplantation (allo-HSCT) provides a unique opportunity to track Epstein-Barr virus (EBV) infection in the context of th... περισσότερα »
Cord blood T cells mediate enhanced antitumor effects compared with adult peripheral blood T cells.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Cord blood T cells mediate enhanced antitumor effects compared with adult peripheral blood T cells.* Blood. 2015 Dec 24;126(26):2882-91 Authors: Hiwarkar P, Qasim W, Ricciardelli I, Gilmour K, Quezada S, Saudemont A, Amrolia P, Veys P Abstract Unrelated cord blood transplantation (CBT) without in vivo T-cell depletion is increasingly used to treat high-risk hematologic malignancies. Following T-replete CBT, naïve CB T cells undergo rapid peripheral expansion with memory-effector differentiation. Emerging data sug... περισσότερα »
Apoptotic induction by pinobanksin and some of its ester derivatives from Sonoran propolis in a B-cell lymphoma cell line.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Apoptotic induction by pinobanksin and some of its ester derivatives from Sonoran propolis in a B-cell lymphoma cell line.* Chem Biol Interact. 2015 Dec 5;242:35-44 Authors: Alday E, Valencia D, Carreño AL, Picerno P, Piccinelli AL, Rastrelli L, Robles-Zepeda R, Hernandez J, Velazquez C Abstract Propolis is a resinous substance produced by honeybees (Apis mellifera) from the selective collection of exudates and bud secretions from several plants. In previous works, we reported the antiproliferative activity of So... περισσότερα »
Aggressive primary cutaneous B-cell lymphomas show increased Angiopoietin-2-induced angiogenesis.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Aggressive primary cutaneous B-cell lymphomas show increased Angiopoietin-2-induced angiogenesis.* Exp Dermatol. 2015 Jun;24(6):424-9 Authors: Teichert M, Stumpf C, Booken N, Wobser M, Nashan D, Hallermann C, Mogler C, Müller CS, Becker JC, Moritz RK, Andrulis M, Nicolay JP, Goerdt S, Thomas M, Klemke CD, Augustin HG, Felcht M Abstract Primary cutaneous large B-cell lymphomas, leg type (PCLBCL/LT) are primary cutaneous B-cell lymphoma (PCBCL) with an intermediate prognosis. Therefore, antracycline-based polychemo...περισσότερα »
Mucinous epithelial ovarian carcinoma.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Mucinous epithelial ovarian carcinoma.* Ann Oncol. 2016 Apr;27(suppl 1):i53-i57 Authors: Perren TJ Abstract Mucinous tumours involving the ovary may be benign, borderline, or malignant. Malignant tumours may be primary or metastatic. Differentiation between primary and metastatic involvement of the ovary is critical for optimal patient management. Even among skilled pathologists, this distinction can be problematic, as can the distinction between borderline ovarian tumour of intestinal type and well-differentiated invasive primary mucinous ovarian carcinoma. Primary invasive muc... περισσότερα »
Low-grade serous carcinoma of the ovary or peritoneum.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Low-grade serous carcinoma of the ovary or peritoneum.* Ann Oncol. 2016 Apr;27(suppl 1):i45-i49 Authors: Gershenson DM Abstract Over the past decade, the strategy for clinical trial design in making progress against epithelial cancers of the ovary/peritoneum/fallopian tube has changed dramatically. The NRG (GOG) Rare Tumor Committee has been a leader in this transformation. No longer does 'one size fit all'. Rather, separate clinical trials for rare subtypes have been developed and, in some cases, completed. An enhanced understanding of their pathologic diagnosis, molecular biol... περισσότερα »
Pharmacokinetics of cabozantinib tablet and capsule formulations in healthy adults.
Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 1 ώρα
*Pharmacokinetics of cabozantinib tablet and capsule formulations in healthy adults.* Anticancer Drugs. 2016 May 2; Authors: Nguyen L, Benrimoh N, Xie Y, Offman E, Lacy S Abstract Cabozantinib capsules (COMETRIQ) are approved for the treatment of patients with progressive metastatic medullary thyroid cancer. Cabozantinib tablets are investigational drug products considered to be potentially preferred pharmaceutical dosing forms. Two phase I open-label single-dose studies in healthy individuals were carried out to characterize the plasma pharmacokinetics of cabozantinib capsule an... περισσότερα »
Current Standards in Treatment of Radioiodine Refractory Thyroid Cancer.
Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 1 ώρα
*Current Standards in Treatment of Radioiodine Refractory Thyroid Cancer.* Curr Treat Options Oncol. 2016 Jun;17(6):30 Authors: Narayanan S, Colevas AD Abstract OPINION STATEMENT: Radioiodine refractory differentiated thyroid cancer (RAI-R DTC) is a challenging malignancy with limited prognosis and treatment options. Recently, clinical trials with targeted therapies have advanced the outlook of these patients, and inhibition of the vascular endothelial growth factor (VEGF) axis has led to the approval of small-molecule tyrosine kinase inhibitors (TKIs) for first-line treatment of... περισσότερα »
The Archives of Pathology & Laboratory Medicine: The Most Widely Read Pathology Journal Today.
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
*The Archives of Pathology & Laboratory Medicine: The Most Widely Read Pathology Journal Today.* Arch Pathol Lab Med. 2016 May 3; Authors: Allen TC Abstract The Archives of Pathology & Laboratory Medicine was first published in 1926 as a subspecialty journal of the American Medical Association. It became the official journal of the College of American Pathologists in 1995. Under the dynamic leadership of its most recent editor-in-chief, Philip T. Cagle, MD, and his vibrant editorial board, the Archives has nearly doubled its impact factor and become the most widely read general p...περισσότερα »
Licensure in the Era of Genomic Medicine.
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
*Licensure in the Era of Genomic Medicine.* Arch Pathol Lab Med. 2016 May 3; Authors: Park JY, Leung ST, Wang J PMID: 27139151 [PubMed - as supplied by publisher] from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1rmINSY via IFTTT
Interobserver Variability in the Diagnosis of Uterine High-Grade Endometrioid Carcinoma.
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
*Interobserver Variability in the Diagnosis of Uterine High-Grade Endometrioid Carcinoma.* Arch Pathol Lab Med. 2016 May 3; Authors: Thomas S, Hussein Y, Bandyopadhyay S, Cote M, Hassan O, Abdulfatah E, Alosh B, Guan H, Soslow RA, Ali-Fehmi R Abstract Context .- Low interobserver diagnostic agreement exists among high-grade endometrial carcinomas. Objective .- To evaluate diagnostic variability in International Federation of Gynecology and Obstetrics (FIGO) grade 3 endometrioid adenocarcinoma (G3EC) in 2 different sign-out practices. Design .- Sixty-six G3EC cases were identified...περισσότερα »
Pituitary Aromatase P450 May Be Involved in Maintenance of the Population of Luteinizing Hormone-Positive Pituitary Cells in Mice
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
As aromatase P450 is located in several pituitary cells, testosterone can be transformed into 17β-estradiol in the gland by the enzyme. The possible role of this transformation in pituitary function remains to be elucidated, but some evidence suggests a physiological and pathophysiological role for pituitary aromatase. To determine its relevance in the modulation of pituitary function, mainly associated with reproduction, luteinizing hormone (LH)-positive cells in the hypophysis of female and male aromatase knockout (ArKO) mice were studied. In all LH-positive cells, significant i... περισσότερα »
Establishment of a Cytocompatible Cell-Free Intervertebral Disc Matrix for Chondrogenesis with Human Bone Marrow-Derived Mesenchymal Stromal Cells
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
Tissue-engineered intervertebral discs (IVDs) utilizing decellularized extracellular matrix (ECM) could be an option for the reconstruction of impaired IVDs due to degeneration or injury. The objective of this study was to prepare a cell-free decellularized human IVD scaffold and to compare neotissue formation in response to recellularization with human IVD cells (hIVDCs) or human bone marrow-derived (hBM) mesenchymal stromal cells (MSCs). IVDs were decellularized via freeze-thaw cycles, detergents and trypsin. Histological staining was performed to monitor cell removal and glycos... περισσότερα »
Treatment of Radiation-Induced Oral Mucositis Using a Novel Accepted Taste of Prolonged Release Mucoadhesive Bi-medicated Double-Layer Buccal Films.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Treatment of Radiation-Induced Oral Mucositis Using a Novel Accepted Taste of Prolonged Release Mucoadhesive Bi-medicated Double-Layer Buccal Films.* AAPS PharmSciTech. 2016 May 2; Authors: Abo Enin HA, El Nabarawy NA, Elmonem RA Abstract The aim of this study was to develop a novel double-layer bi-medicated prolonged release mucoadhesive buccal film (MBF) containing lidocaine hydrochloride (LC) and diclofenac potassium (DK). The ultimate goal of the prepared system is the treatment of radiation-induced oral mucositis pain with improved patient acceptance. MBFs were prepared usin... περισσότερα »
Toxic epidermal necrolysis in patient with malignant astrocytoma.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Related Articles *Toxic epidermal necrolysis in patient with malignant astrocytoma.* Pol Merkur Lekarski. 2016 Jan;40(235):25-7 Authors: Kaczmarska-Turek D, Bartnik P, Kacperczyk J, Orlewski J, Olszewska M, Krasnodębska-Kiljańska M Abstract UNLABELLED: Toxic epidermal necrolysis (TEN) is a severe, life-threatening mucocutaneus adverse reaction, most commonly triggered by medication. Treatment in some aspects is still controversial. CASE REPORT: Patient with malignant astrocytoma, treated with palliative radiotherapy, developed massive erythema with bullae. Patient suffered from t... περισσότερα »
Cortical encoding and neurophysiological tracking of intensity and pitch cues signaling English stress patterns in native and nonnative speakers.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Cortical encoding and neurophysiological tracking of intensity and pitch cues signaling English stress patterns in native and nonnative speakers.* Brain Lang. 2016 Apr 30;155-156:49-57 Authors: Chung WL, Bidelman GM Abstract We examined cross-language differences in neural encoding and tracking of intensity and pitch cues signaling English stress patterns. Auditory mismatch negativities (MMNs) were recorded in English and Mandarin listeners in response to contrastive English pseudowords whose primary stress occurred either on the first or second syllable (i.e., "nocTICity" vs. "... περισσότερα »
The impact of thought disorder on therapeutic alliance and personal recovery in schizophrenia and schizoaffective disorder: An exploratory study.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*The impact of thought disorder on therapeutic alliance and personal recovery in schizophrenia and schizoaffective disorder: An exploratory study.* Psychiatry Res. 2016 May 30;239:92-98 Authors: Cavelti M, Homan P, Vauth R Abstract Thought and language disorders are a main feature of schizophrenia. The aim of the study is to explore the impact of thought disorder on therapeutic alliance and personal recovery because of its interference with verbal communication. Thought disorder, positive and negative symptoms (Positive and Negative Syndrome Scale), functioning (Modified Global A...περισσότερα »
Child Readers' Eye Movements in Reading Thai.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Child Readers' Eye Movements in Reading Thai.* Vision Res. 2016 Apr 29; Authors: Kasisopa B, Reilly RG, Luksaneeyanawin S, Burnham D Abstract It has recently been found that adult native readers of Thai, an alphabetic scriptio continua language, engage similar oculomotor patterns as readers of languages written with spaces between words; despite the lack of inter-word spaces, first and last characters of a word appear to guide optimal placement of Thai readers' eye movements, just to the left of word-centre. The issue addressed by the research described here is whether eye movem...περισσότερα »
Toxic epidermal necrolysis in patient with malignant astrocytoma.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Related Articles *Toxic epidermal necrolysis in patient with malignant astrocytoma.* Pol Merkur Lekarski. 2016 Jan;40(235):25-7 Authors: Kaczmarska-Turek D, Bartnik P, Kacperczyk J, Orlewski J, Olszewska M, Krasnodębska-Kiljańska M Abstract UNLABELLED: Toxic epidermal necrolysis (TEN) is a severe, life-threatening mucocutaneus adverse reaction, most commonly triggered by medication. Treatment in some aspects is still controversial. CASE REPORT: Patient with malignant astrocytoma, treated with palliative radiotherapy, developed massive erythema with bullae. Patient suffered from t... περισσότερα »
Anatomie und Neuromonitoring des bifaszikulären N. recurrens
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
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Julius-Springer-Preis für Chirurgie 2016 verliehen
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
from #ENT via xlomafota13 on Inoreader http://ift.tt/1X7HALS via IFTTT
Cortical encoding and neurophysiological tracking of intensity and pitch cues signaling English stress patterns in native and nonnative speakers.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Cortical encoding and neurophysiological tracking of intensity and pitch cues signaling English stress patterns in native and nonnative speakers.* Brain Lang. 2016 Apr 30;155-156:49-57 Authors: Chung WL, Bidelman GM Abstract We examined cross-language differences in neural encoding and tracking of intensity and pitch cues signaling English stress patterns. Auditory mismatch negativities (MMNs) were recorded in English and Mandarin listeners in response to contrastive English pseudowords whose primary stress occurred either on the first or second syllable (i.e., "nocTICity" vs. "... περισσότερα »
The impact of thought disorder on therapeutic alliance and personal recovery in schizophrenia and schizoaffective disorder: An exploratory study.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*The impact of thought disorder on therapeutic alliance and personal recovery in schizophrenia and schizoaffective disorder: An exploratory study.* Psychiatry Res. 2016 May 30;239:92-98 Authors: Cavelti M, Homan P, Vauth R Abstract Thought and language disorders are a main feature of schizophrenia. The aim of the study is to explore the impact of thought disorder on therapeutic alliance and personal recovery because of its interference with verbal communication. Thought disorder, positive and negative symptoms (Positive and Negative Syndrome Scale), functioning (Modified Global A...περισσότερα »
Child Readers' Eye Movements in Reading Thai.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Child Readers' Eye Movements in Reading Thai.* Vision Res. 2016 Apr 29; Authors: Kasisopa B, Reilly RG, Luksaneeyanawin S, Burnham D Abstract It has recently been found that adult native readers of Thai, an alphabetic scriptio continua language, engage similar oculomotor patterns as readers of languages written with spaces between words; despite the lack of inter-word spaces, first and last characters of a word appear to guide optimal placement of Thai readers' eye movements, just to the left of word-centre. The issue addressed by the research described here is whether eye movem...περισσότερα »
Giving patients a voice when they need one most.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Related Articles *Giving patients a voice when they need one most.* Hosp Health Netw. 2016 Feb;90(2):19 Authors: Arcuri L PMID: 27017816 [PubMed - indexed for MEDLINE] from #ENT via xlomafota13 on Inoreader http://ift.tt/21QSZi0 via IFTTT
Short-term and long-term test-retest reliability of the Nasality Severity Index 2.0
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 3 May 2016 *Source:*Journal of Communication Disorders Author(s): Kim Bettens, Floris L. Wuyts, Evelien D'haeseleer, Anke Luyten, Iris Meerschman, Carole Van Crayelynghe, Kristiane M. Van Lierde PurposeThe Nasality Severity Index 2.0 (NSI 2.0) forms a new, multiparametric approach in the assessment of hypernasality. To enable clinical implementation of this index, the short- and long-term test-retest reliability of this index was explored.MethodsIn 40 normal-speaking adults (mean age 32y, SD 11, 18-56y) and 29 normalspeaking children (mean age 8y, ... περισσότερα »
Reconstruction of human oncological tracheal defects with xenogenic acellular dermal matrix
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 24 April 2016 *Source:*Auris Nasus Larynx Author(s): Ping Li, Shisheng Li, Qinglai Tang, Xiangbo He, Danhui Yin, Shuang Wang, Xinming Yang ObjectiveThis study aimed to explore the effectiveness of xenogenic acellular dermal matrix (xeno-ADM) in tracheal reconstruction.MethodTwo patients were treated with this surgical method to reconstruct the trachea in 2013. The patients were diagnosed with tracheal adenoid cystic carcinoma by histopathological biopsy. The tumor was resected with half of the tracheal circumference and repaired by xeno-ADM. The pa... περισσότερα »
Cavernous sinus thrombosis during pregnancy
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 14 April 2016 *Source:*Auris Nasus Larynx Author(s): Fernando López, Elena Santamarta, Patricia Martínez, Antonio Sáiz-Ayala, José L. Llorente Cavernous sinus thrombosis (CST) represents a rare but devastating disease process that may be associated with significant long-term patient morbidity or mortality. Rapid diagnosis and aggressive medical and surgical management are imperative for patients with CST. We present the case of a 24-year-old pregnant woman with intraorbital abscess and CST secondary to Streptococcus milleri. Surgical intervention i...περισσότερα »
Facial paralysis induced by ear inoculation of herpes simplex virus in rat
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 17 April 2016 *Source:*Auris Nasus Larynx Author(s): Takashi Fujiwara, Seiji Matsuda, Junya Tanaka, Naohito Hato ObjectiveBell's palsy is caused by the reactivation of herpes simplex virus type 1 (HSV-1). Using Balb/c mice inoculated with the KOS strain of HSV-1, we previously developed an animal disease model that simulated mild Bell's palsy. The current study developed an animal disease model of more severe facial palsy than that seen in the mouse model.MethodsThree-week-old female Wister rats weighing 60–80g were inoculated on the auricle with HS...περισσότερα »
Hernia of the tympanic membrane
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 29 April 2016 *Source:*Auris Nasus Larynx Author(s): Ryoukichi Ikeda, Hiromitsu Miyazaki, Tetsuaki Kawase, Yukio Katori, Toshimitsu Kobayashi Although tympanic bulging is commonly encountered, tympanic herniation occupying the external auditory canal is extremely rare. A 66-year-old man was presented to our hospital with left aural fullness, bilateral hearing loss and otorrhea. Preoperative findings suggested tympanic membrane (TM) hernia located in the left external auditory canal. We performed total resection of the soft mass by a transcanal appr...περισσότερα »
Endoscopic approach for cochlear implantation in advanced otosclerosis: A case report
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 19 April 2016 *Source:*Auris Nasus Larynx Author(s): Daniele Marchioni, Davide Soloperto, Luca Bianconi, Maria C. Guarnaccia, Elisabetta Genovese, Livio Presutti HypothesisOssification of the cochlea was once considered to be a contraindication for cochlear implantation. Advances in cochlear implant technology and coding strategies have led to developments in different surgical procedures to manage cochlear ossification. The endoscopic technique allows a direct approach to the round window and the cochlea, especially in remodeled labyrinth, allowin...περισσότερα »
Evaluation of life quality, self-confidence and sexual functions in patients with total and partial laryngectomy
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 16 April 2016 *Source:*Auris Nasus Larynx Author(s): Ayşegül Batıoğlu-Karaaltın, Zerrin Binbay, Özgür Yiğit, Zehra Dönmez ObjectiveIn this study patients who have undergone partial (PL) or total laryngectomy (TL) were evaluated for life quality, self-esteem and sexual dysfunctions.Methods108 patients who received TL or PL without tracheostoma were included in this study. During patient interview, sociodemographical data form, European Organization for Research and Treatment of Cancer, Life Questionnaire Core 30 Items, Cancer and Head and Neck modul... περισσότερα »
Complications after cochlear implantation in adult patients. 10-Year retrospective analysis of a tertiary academic centre
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 14 April 2016 *Source:*Auris Nasus Larynx Author(s): Carlos Miguel Chiesa Estomba, Teresa Rivera Schmitz, Frank Alberto Betances Reinoso, Lenin Dominguez Collado, Manuel Estevez Garcia, Ana Isabel Lorenzo Lorenzo ObjectiveCochlear implants (CI) are electronic devices that enable the auditory rehabilitation and the management of individuals with severe to profound bilateral hearing loss, and nowadays, advanced age is not considered a contraindication for cochlear implantation and several studies have shown that older adults do benefit from CI, with ...περισσότερα »
Comparison of tinnitus and psychological aspects between the younger and older adult patients with tinnitus
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 4 May 2016 *Source:*Auris Nasus Larynx Author(s): So Young Park, Jung Ju Han, Jae Hyung Hwang, Eul Sung Whang, Sang Won Yeo, Shi Nae Park ObjectiveTo explore the differences in various tinnitus-related features and psychological aspects between the younger and older adult patients with tinnitus.MethodsWe retrospectively reviewed the clinical data of the adult patients who visited our tinnitus clinic in 2013 and completed full tinnitus assessment including audiometry, tinnitus matching, standardized tinnitus questionnaires, and psychometric question... περισσότερα »
Drug delivery system of basic fibroblast growth factor using gelatin hydrogel for restoration of acute vocal fold scar
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 26 April 2016 *Source:*Auris Nasus Larynx Author(s): Toshiki Kobayashi, Masanobu Mizuta, Nao Hiwatashi, Yo Kishimoto, Tatsuo Nakamura, Shin-ichi Kanemaru, Shigeru Hirano ObjectiveThere continue to be therapeutic challenges in the management of vocal fold scarring. We previously showed that basic fibroblast growth factor (bFGF) injection has therapeutic potential for vocal fold scarring. However, the working time of bFGF is relatively short, and multiple injections were required in many cases to obtain the regenerative effect. An efficacious deliver... περισσότερα »
Thyroid carcinoma with rhabdoid phenotype: Case report with review of the literature
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 21 April 2016 *Source:*Auris Nasus Larynx Author(s): Yen-Ting Lu, Hsin-I Huang, An-Hung Yang, Shyh-Kuan Tai ObjectiveThis paper aims to comprehensively document a rare case of thyroid carcinoma with rhabdoid phenotype and literature review of this disease.MethodsA 59-year-old man presented with a rapidly enlarging, painful left lateral cervical mass. CT scan revealed a tumor over the left the thyroid gland with multiple left cervical lymphadenopathy over left level II–IV and level VI. Fine-needle aspiration cytology reported carcinoma, type undeter...περισσότερα »
Change of nystagmus direction during a head-roll test in lateral semicircular canal cupulolithiasis
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 18 April 2016 *Source:*Auris Nasus Larynx Author(s): Jung Eun Shin, Kyung-Hwa Jeong, Sung Hwan Ahn, Chang-Hee Kim ObjectiveTo demonstrate positional nystagmus during a head-roll test in two patients with lateral semicircular canal (LSCC) cupulolithiasis who presented with spontaneous detachment of otoliths from the LSCC cupula, and to confirm that otoliths may adhere to both the utricle and canal sides of the cupula.Patients and methodsUsing video nystagmography, positional nystagmus was evaluated in two patients with LSCC cupulolithiasis who showe...περισσότερα »
A case of patulous Eustachian tube associated with dizziness induced by nasal respiration
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 16 April 2016 *Source:*Auris Nasus Larynx Author(s): Naoharu Kitajima, Akemi Sugita-Kitajima, Seiji Kitajima ObjectiveTo determine the relationship between Eustachian tube function and inner ear function in patulous Eustachian tube (pET).MethodsWe encountered a patient with pET accompanied by dizziness that was induced by nasal respiration. Eye movements were recorded using video-oculography, and Eustachian tube function was assessed using a Eustachian tube function analyzer. Horizontal and vertical components of pupil position were assessed to tes...περισσότερα »
A case of recurrent malignant triton tumor successfully treated with radiotherapy
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 15 April 2016 *Source:*Auris Nasus Larynx Author(s): Makoto Yasuda, Yoko Muto, Toshihiro Kuremoto, Kentaro Murakami, Toshinori Onisihi, Atsuhide Koida, Takaaki Inui, Yasuo Hisa A 15-year-old female was previously admitted to another hospital because of painless swelling of the lateral right nasal ala for 2 months. Magnetic resonance imaging revealed an expansive enhancing lesion in close proximity to the anterior surface of the right maxillary sinus and lateral wall of the right nasal cavity. Tumor extirpation was performed via the supragingival tr... περισσότερα »
Symptomatic lymphoepithelial cyst of the pancreas: successful treatment without pancreatic resection.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Symptomatic lymphoepithelial cyst of the pancreas: successful treatment without pancreatic resection.* J Surg Case Rep. 2016;2016(4) Authors: Ruggero JM, Prakash SN Abstract Lymphoepithelial cysts (LECs) of the pancreas are rare benign lesions with unknown pathogenesis. LECs are true cysts that mimic pseudocysts and cystic neoplasms making diagnosis challenging. We report a case of a symptomatic LEC of the pancreas in a 67-year-old man who had severe epigastric pain. Workup including computed tomography and endoscopic ultrasound were non-diagnostic. The patient underwent attempt...περισσότερα »
Evaluation of the diagnostic value of 64 simultaneously measured autoantibodies for early detection of gastric cancer.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Evaluation of the diagnostic value of 64 simultaneously measured autoantibodies for early detection of gastric cancer.* Sci Rep. 2016;6:25467 Authors: Werner S, Chen H, Butt J, Michel A, Knebel P, Holleczek B, Zörnig I, Eichmüller SB, Jäger D, Pawlita M, Waterboer T, Brenner H Abstract Autoantibodies against tumor-associated antigens (TAAs) have been suggested as biomarkers for early detection of gastric cancer. However, studies that systematically assess the diagnostic performance of a large number of autoantibodies are rare. Here, we used bead-based multiplex serology to simul...περισσότερα »
Pituitary Aromatase P450 May Be Involved in Maintenance of the Population of Luteinizing Hormone-Positive Pituitary Cells in Mice
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
As aromatase P450 is located in several pituitary cells, testosterone can be transformed into 17β-estradiol in the gland by the enzyme. The possible role of this transformation in pituitary function remains to be elucidated, but some evidence suggests a physiological and pathophysiological role for pituitary aromatase. To determine its relevance in the modulation of pituitary function, mainly associated with reproduction, luteinizing hormone (LH)-positive cells in the hypophysis of female and male aromatase knockout (ArKO) mice were studied. In all LH-positive cells, significant i... περισσότερα »
Establishment of a Cytocompatible Cell-Free Intervertebral Disc Matrix for Chondrogenesis with Human Bone Marrow-Derived Mesenchymal Stromal Cells
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
Tissue-engineered intervertebral discs (IVDs) utilizing decellularized extracellular matrix (ECM) could be an option for the reconstruction of impaired IVDs due to degeneration or injury. The objective of this study was to prepare a cell-free decellularized human IVD scaffold and to compare neotissue formation in response to recellularization with human IVD cells (hIVDCs) or human bone marrow-derived (hBM) mesenchymal stromal cells (MSCs). IVDs were decellularized via freeze-thaw cycles, detergents and trypsin. Histological staining was performed to monitor cell removal and glycos... περισσότερα »
Head and neck microvascular free flap reconstruction: An analysis of unplanned readmissions.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Head and neck microvascular free flap reconstruction: An analysis of unplanned readmissions. Laryngoscope. 2016 May 2; Authors: Carniol ET, Marchiano E, Brady JS, Merchant AM, Eloy JA, Baredes S, Park RC Abstract OBJECTIVES/HYPOTHESIS: Unplanned readmissions within 30 days of surgery represent a significant marker for healthcare quality. Small institutional studies have described rates of readmission […]
Beyond melanoma: inhibiting the PD-1/PD-L1 pathway in solid tumors.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Beyond melanoma: inhibiting the PD-1/PD-L1 pathway in solid tumors. Immunotherapy. 2016 May;8(5):583-600 Authors: Gentzler R, Hall R, Kunk PR, Gaughan E, Dillon P, Slingluff CL, Rahma OE Abstract Immune checkpoint inhibitors have been identified as breakthrough treatment in melanoma given its dramatic response to PD-1/PD-L1 blockade. This is likely to extend to many other cancers […]
Long-term effects of intracochlear electrical stimulation with looped patterns on tinnitus: A case study.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Long-term effects of intracochlear electrical stimulation with looped patterns on tinnitus: A case study. Ear Nose Throat J. 2016 Apr-May;95(4-5):E9-E15 Authors: Arts RA, George EL, Griessner A, Zierhofer C, Stokroos RJ Abstract Electrical stimulation by cochlear implant (CI) has been proven to be a viable treatment option for tinnitus in many recent studies. In addition, […]
The aging physician and surgeon.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The aging physician and surgeon. Ear Nose Throat J. 2016 Apr-May;95(4-5):E35-E48 Authors: Sataloff RT, Hawkshaw M, Kutinsky J, Maitz EA Abstract As the population of aging physicians increases, methods of assessing physicians’ cognitive function and predicting clinically significant changes in clinical performance become increasingly important. Although several approaches have been suggested, no evaluation system is […]
Synchronous bilateral tonsillar squamous cell carcinoma related to human papillomavirus: Two case reports and a brief review of the literature.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Synchronous bilateral tonsillar squamous cell carcinoma related to human papillomavirus: Two case reports and a brief review of the literature. Ear Nose Throat J. 2016 Apr-May;95(4-5):E30-E34 Authors: Rasband-Lindquist A, Shnayder Y, O’Neil M Abstract Human papillomavirus (HPV) was recently identified as a risk factor for oropharyngeal squamous cell carcinoma (SCC) independent of tobacco and alcohol […]
Intramuscular hemangiomas of the head and neck: Three case reports.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Intramuscular hemangiomas of the head and neck: Three case reports. Ear Nose Throat J. 2016 Apr-May;95(4-5):E27-E29 Authors: Aydin Ö, Keskin G, İşeri M, Ulubil A, Demir Kuru F, Oran A, Derin S Abstract Hemangiomas are tumors of vascular origin that frequently occur on the skin and mucosal surfaces in the pediatric age group. Hemangiomas located […]
A large vestibular schwannoma after recent negative MRI: A case report.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
A large vestibular schwannoma after recent negative MRI: A case report. Ear Nose Throat J. 2016 Apr-May;95(4-5):E24-E26 Authors: Muelleman TJ, Lin J Abstract Vestibular schwannomas are, on average, slowly growing tumors that may remain quiescent for some time before manifesting themselves symptomatically or being found incidentally on imaging. We describe a case of a vestibular […]
If cytology of Warthin tumor is accurate, can management be conservative?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
If cytology of Warthin tumor is accurate, can management be conservative? Ear Nose Throat J. 2016 Apr-May;95(4-5):185-188 Authors: Vlantis AC, Ng SK, Mak CK, Cheung JM, Chan AB, van Hasselt CA Abstract We conducted a retrospective study to assess the accuracy of fine-needle aspiration cytology (FNAC) in the diagnosis of Warthin tumor and to evaluate […]
Is unenhanced 18F-FDG-PET/CT better than enhanced CT in the detection of retropharyngeal lymph node metastasis in nasopharyngeal carcinoma?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Is unenhanced 18F-FDG-PET/CT better than enhanced CT in the detection of retropharyngeal lymph node metastasis in nasopharyngeal carcinoma? Ear Nose Throat J. 2016 Apr-May;95(4-5):178-184 Authors: Wu IS, Hung GU, Chang BL, Liu CK, Chang TH, Lee HS, Chen MK Abstract Positron-emission tomography/computed tomography (PET/CT) has been proposed as a means to enhance the pretreatment evaluation […]
Pneumocephalus after insertion of an inflatable nasal tampon for the management of epistaxis.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Pneumocephalus after insertion of an inflatable nasal tampon for the management of epistaxis. Ear Nose Throat J. 2016 Apr-May;95(4-5):172-174 Authors: Kimple AJ, Ferguson MO Abstract While the fundamental principles of epistaxis management have not changed over the decades, the methods by which tamponade is achieved have been evolving. Inflatable nasal tampons are being used and […]
Cow’s milk allergy in Dutch children: an epigenetic pilot survey
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Cow’s milk allergy (CMA) is a common disease in infancy. Early environmental factors are likely to contribute to CMA. It is known that epigenetic gene regulation can be altered by environmental factors. We hav… from Allergy via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SN9gjT via IFTTT
Giving patients a voice when they need one most.
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Related Articles *Giving patients a voice when they need one most.* Hosp Health Netw. 2016 Feb;90(2):19 Authors: Arcuri L PMID: 27017816 [PubMed - indexed for MEDLINE] from Speech via a.lsfakia on Inoreader http://ift.tt/21QSZi0 via IFTTT
Short-term and long-term test-retest reliability of the Nasality Severity Index 2.0
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 3 May 2016 *Source:*Journal of Communication Disorders Author(s): Kim Bettens, Floris L. Wuyts, Evelien D'haeseleer, Anke Luyten, Iris Meerschman, Carole Van Crayelynghe, Kristiane M. Van Lierde PurposeThe Nasality Severity Index 2.0 (NSI 2.0) forms a new, multiparametric approach in the assessment of hypernasality. To enable clinical implementation of this index, the short- and long-term test-retest reliability of this index was explored.MethodsIn 40 normal-speaking adults (mean age 32y, SD 11, 18-56y) and 29 normalspeaking children (mean age 8y, ... περισσότερα »
Reconstruction of human oncological tracheal defects with xenogenic acellular dermal matrix
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 24 April 2016 *Source:*Auris Nasus Larynx Author(s): Ping Li, Shisheng Li, Qinglai Tang, Xiangbo He, Danhui Yin, Shuang Wang, Xinming Yang ObjectiveThis study aimed to explore the effectiveness of xenogenic acellular dermal matrix (xeno-ADM) in tracheal reconstruction.MethodTwo patients were treated with this surgical method to reconstruct the trachea in 2013. The patients were diagnosed with tracheal adenoid cystic carcinoma by histopathological biopsy. The tumor was resected with half of the tracheal circumference and repaired by xeno-ADM. The pa... περισσότερα »
Cavernous sinus thrombosis during pregnancy
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 14 April 2016 *Source:*Auris Nasus Larynx Author(s): Fernando López, Elena Santamarta, Patricia Martínez, Antonio Sáiz-Ayala, José L. Llorente Cavernous sinus thrombosis (CST) represents a rare but devastating disease process that may be associated with significant long-term patient morbidity or mortality. Rapid diagnosis and aggressive medical and surgical management are imperative for patients with CST. We present the case of a 24-year-old pregnant woman with intraorbital abscess and CST secondary to Streptococcus milleri. Surgical intervention i...περισσότερα »
Facial paralysis induced by ear inoculation of herpes simplex virus in rat
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 17 April 2016 *Source:*Auris Nasus Larynx Author(s): Takashi Fujiwara, Seiji Matsuda, Junya Tanaka, Naohito Hato ObjectiveBell's palsy is caused by the reactivation of herpes simplex virus type 1 (HSV-1). Using Balb/c mice inoculated with the KOS strain of HSV-1, we previously developed an animal disease model that simulated mild Bell's palsy. The current study developed an animal disease model of more severe facial palsy than that seen in the mouse model.MethodsThree-week-old female Wister rats weighing 60–80g were inoculated on the auricle with HS...περισσότερα »
Hernia of the tympanic membrane
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 29 April 2016 *Source:*Auris Nasus Larynx Author(s): Ryoukichi Ikeda, Hiromitsu Miyazaki, Tetsuaki Kawase, Yukio Katori, Toshimitsu Kobayashi Although tympanic bulging is commonly encountered, tympanic herniation occupying the external auditory canal is extremely rare. A 66-year-old man was presented to our hospital with left aural fullness, bilateral hearing loss and otorrhea. Preoperative findings suggested tympanic membrane (TM) hernia located in the left external auditory canal. We performed total resection of the soft mass by a transcanal appr...περισσότερα »
Endoscopic approach for cochlear implantation in advanced otosclerosis: A case report
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 19 April 2016 *Source:*Auris Nasus Larynx Author(s): Daniele Marchioni, Davide Soloperto, Luca Bianconi, Maria C. Guarnaccia, Elisabetta Genovese, Livio Presutti HypothesisOssification of the cochlea was once considered to be a contraindication for cochlear implantation. Advances in cochlear implant technology and coding strategies have led to developments in different surgical procedures to manage cochlear ossification. The endoscopic technique allows a direct approach to the round window and the cochlea, especially in remodeled labyrinth, allowin...περισσότερα »
Evaluation of life quality, self-confidence and sexual functions in patients with total and partial laryngectomy
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 16 April 2016 *Source:*Auris Nasus Larynx Author(s): Ayşegül Batıoğlu-Karaaltın, Zerrin Binbay, Özgür Yiğit, Zehra Dönmez ObjectiveIn this study patients who have undergone partial (PL) or total laryngectomy (TL) were evaluated for life quality, self-esteem and sexual dysfunctions.Methods108 patients who received TL or PL without tracheostoma were included in this study. During patient interview, sociodemographical data form, European Organization for Research and Treatment of Cancer, Life Questionnaire Core 30 Items, Cancer and Head and Neck modul... περισσότερα »
Complications after cochlear implantation in adult patients. 10-Year retrospective analysis of a tertiary academic centre
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 14 April 2016 *Source:*Auris Nasus Larynx Author(s): Carlos Miguel Chiesa Estomba, Teresa Rivera Schmitz, Frank Alberto Betances Reinoso, Lenin Dominguez Collado, Manuel Estevez Garcia, Ana Isabel Lorenzo Lorenzo ObjectiveCochlear implants (CI) are electronic devices that enable the auditory rehabilitation and the management of individuals with severe to profound bilateral hearing loss, and nowadays, advanced age is not considered a contraindication for cochlear implantation and several studies have shown that older adults do benefit from CI, with ...περισσότερα »
Comparison of tinnitus and psychological aspects between the younger and older adult patients with tinnitus
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 4 May 2016 *Source:*Auris Nasus Larynx Author(s): So Young Park, Jung Ju Han, Jae Hyung Hwang, Eul Sung Whang, Sang Won Yeo, Shi Nae Park ObjectiveTo explore the differences in various tinnitus-related features and psychological aspects between the younger and older adult patients with tinnitus.MethodsWe retrospectively reviewed the clinical data of the adult patients who visited our tinnitus clinic in 2013 and completed full tinnitus assessment including audiometry, tinnitus matching, standardized tinnitus questionnaires, and psychometric question... περισσότερα »
Drug delivery system of basic fibroblast growth factor using gelatin hydrogel for restoration of acute vocal fold scar
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 26 April 2016 *Source:*Auris Nasus Larynx Author(s): Toshiki Kobayashi, Masanobu Mizuta, Nao Hiwatashi, Yo Kishimoto, Tatsuo Nakamura, Shin-ichi Kanemaru, Shigeru Hirano ObjectiveThere continue to be therapeutic challenges in the management of vocal fold scarring. We previously showed that basic fibroblast growth factor (bFGF) injection has therapeutic potential for vocal fold scarring. However, the working time of bFGF is relatively short, and multiple injections were required in many cases to obtain the regenerative effect. An efficacious deliver... περισσότερα »
Thyroid carcinoma with rhabdoid phenotype: Case report with review of the literature
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 21 April 2016 *Source:*Auris Nasus Larynx Author(s): Yen-Ting Lu, Hsin-I Huang, An-Hung Yang, Shyh-Kuan Tai ObjectiveThis paper aims to comprehensively document a rare case of thyroid carcinoma with rhabdoid phenotype and literature review of this disease.MethodsA 59-year-old man presented with a rapidly enlarging, painful left lateral cervical mass. CT scan revealed a tumor over the left the thyroid gland with multiple left cervical lymphadenopathy over left level II–IV and level VI. Fine-needle aspiration cytology reported carcinoma, type undeter...περισσότερα »
Change of nystagmus direction during a head-roll test in lateral semicircular canal cupulolithiasis
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 18 April 2016 *Source:*Auris Nasus Larynx Author(s): Jung Eun Shin, Kyung-Hwa Jeong, Sung Hwan Ahn, Chang-Hee Kim ObjectiveTo demonstrate positional nystagmus during a head-roll test in two patients with lateral semicircular canal (LSCC) cupulolithiasis who presented with spontaneous detachment of otoliths from the LSCC cupula, and to confirm that otoliths may adhere to both the utricle and canal sides of the cupula.Patients and methodsUsing video nystagmography, positional nystagmus was evaluated in two patients with LSCC cupulolithiasis who showe...περισσότερα »
A case of patulous Eustachian tube associated with dizziness induced by nasal respiration
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 16 April 2016 *Source:*Auris Nasus Larynx Author(s): Naoharu Kitajima, Akemi Sugita-Kitajima, Seiji Kitajima ObjectiveTo determine the relationship between Eustachian tube function and inner ear function in patulous Eustachian tube (pET).MethodsWe encountered a patient with pET accompanied by dizziness that was induced by nasal respiration. Eye movements were recorded using video-oculography, and Eustachian tube function was assessed using a Eustachian tube function analyzer. Horizontal and vertical components of pupil position were assessed to tes...περισσότερα »
A case of recurrent malignant triton tumor successfully treated with radiotherapy
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 15 April 2016 *Source:*Auris Nasus Larynx Author(s): Makoto Yasuda, Yoko Muto, Toshihiro Kuremoto, Kentaro Murakami, Toshinori Onisihi, Atsuhide Koida, Takaaki Inui, Yasuo Hisa A 15-year-old female was previously admitted to another hospital because of painless swelling of the lateral right nasal ala for 2 months. Magnetic resonance imaging revealed an expansive enhancing lesion in close proximity to the anterior surface of the right maxillary sinus and lateral wall of the right nasal cavity. Tumor extirpation was performed via the supragingival tr... περισσότερα »
A UNITED CLASSIFICATION IN CARCINOMA OF THE ESOPHAGUS AND THE CARDIA BASED ON THE LYMPH METASTASIS.
Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα
Related Articles *A UNITED CLASSIFICATION IN CARCINOMA OF THE ESOPHAGUS AND THE CARDIA BASED ON THE LYMPH METASTASIS.* Khirurgiia (Sofiia). 2015;81(3):123-34 Authors: Tsenovski Y, Tchervenyakov A Abstract The problem of the surgical treatment of cancer of the esophagus-gastric transition is up to date until today and has caused disagreements between the surgeons. This is one of the most aggressive visceral tumors. Metastasis is very specific due to the specificity of lymph edema. We operated 213 patients for four years period, 162 of them male and 51 - female. Cancer cardia and ... περισσότερα »
Buried adenocarcinoma hidden by normal squamous epithelium in Barrett's esophagus: should we enlarge the margins for endoscopic resections?
Alexandros G. SfakianakisστοThe OesophagusΠριν από 1 ώρα
Related Articles *Buried adenocarcinoma hidden by normal squamous epithelium in Barrett's esophagus: should we enlarge the margins for endoscopic resections?* Endoscopy. 2015;47 Suppl 1 UCTN:E439-41 Authors: Erard-Poinsot D, Pioche M, Chabrun E, Rivory J, Belleannee G, Hervieu V, Ponchon T PMID: 26397860 [PubMed - indexed for MEDLINE] from pubmed: esophageal cancer http://ift.tt/1ZbGihk via IFTTT
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