Salmonella enterica Subspecies diarizonae Maxillary Sinusitis in a Snake Handler: First Report
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 δευτερόλεπτα
In this study, we report the first case of reptile-associated maxillary sinusitis due to Salmonella enterica subspecies diarizonae in a snake handler and the third case of salmonella-associated sinusitis worldwide. The case highlights the potential of respiratory transmission and atypical salmonellosis presentations. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Zgj3mj via IFTTT
Nærvær og fravær
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 δευτερόλεπτα
Høsten 2016 innføres det nye fraværsregler i skolen. Elevene vil da trenge legeerklæring ved fravær av helsegrunner. Det kan bli utfordrende for både legene, foreldrene og ungdommene selv. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OfbW84 via IFTTT
Bilateral Subpectoral Interfascial Plane Catheters for Analgesia for Sternal Fractures: A Case Report.
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
Objectives: Sternal fractures occur after deceleration injuries such as falls and road traffic accidents. Recovery from isolated fractures is excellent, but mortality increases dramatically with concurrent chest injuries such as rib fractures and soft tissue injuries. Short-term complications include chest pain, which prevents patients from taking deep breaths and coughing, thereby predisposing them to chest infections. Case Report: We present a case of a 73-year-old woman with sternal fracture in whom enteral analgesia was inadequate and who was intolerant to intravenous opiates. C... περισσότερα »
Reply to: the use of advanced airway management devices in clinical practice
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1W7cK6t via IFTTT
Cardiac troponins and volatile anaesthetics in on-pump coronary surgery: How much longer do we need to state the obvious?
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1W7cLY6 via IFTTT
Bilateral hypoglossal nerve palsy and unilateral recurrent laryngeal nerve palsy following lumbar discectomy: A case report
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1W7cLYg via IFTTT
Cardiac troponins and volatile anaesthetics in coronary artery bypass graft surgery: A systematic review, meta-analysis and trial sequential analysis
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
[image: image]BACKGROUND: Reports from animal studies indicate that volatile anaesthetics protect the myocardium against the effects of acute ischaemia–reperfusion injury by reducing infarct size. This cardioprotective effect in the clinical setting of coronary artery bypass graft (CABG) surgery, where the heart is subjected to global ischaemia–reperfusion injury, remains controversial. OBJECTIVE: The objective was to demonstrate that clinical studies investigating the cardioprotective effect of volatile anaesthetics on cardiac troponins in CABG are no longer warranted. We also inve... περισσότερα »
Black or white coffee before anaesthesia?: A randomised crossover trial
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
[image: image]BACKGROUND: In current preoperative fasting guidelines, coffee with milk is still regarded by many as solid food. Evidence on the consequences for gastric volume of adding milk to coffee 2 h before anaesthesia is still weak. OBJECTIVES: The aim of this study was to compare the gastric volume by MRI in healthy volunteers after drinking coffee with and without added milk. DESIGN: A randomised crossover trial where all participants were exposed to three coffee and milk mixtures performed as a noninferiority study with a predefined noninferiority limit of 12 ml. SETTING: D... περισσότερα »
Identifying optimal heparin management during cardiopulmonary bypass in obese patients: A prospective observational comparative study
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
[image: image]BACKGROUND: The heparin regimen providing anticoagulation during cardiopulmonary bypass (CPB) is usually adapted to total body weight (TBW), but may be inaccurate in obese patients in whom TBW exceeds their ideal body weight. OBJECTIVES: The objective is to compare the effects of heparin injection based on TBW on haemostatic parameters between obese and nonobese patients during cardiac surgery and to calculate the optimal heparin regimen. DESIGN: Prospective comparative study. SETTING: University hospital. PATIENTS: Two groups of 50 patients (BMI≥ or from Anaesthesia v... περισσότερα »
Changes in intracranial pressure and cerebral blood flow during volatile anaesthesia: Fact or fiction?
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
[image: image]No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1W7cK6r via IFTTT
Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
[image: image]BACKGROUND: Etomidate is perceived as preserving haemodynamic stability during induction of anaesthesia. It is also associated with adrenocortical dysfunction. The risk/benefit relationship is controversial. OBJECTIVES: We tested the hypotheses that single-dose etomidate increases cumulative vasopressor requirement, time to extubation and length of stay in the ICU. DESIGN: Double-blind randomised controlled trial. SETTING: Bern University Hospital, Switzerland, from November 2006 to December 2009. PATIENTS: There were 90 patients undergoing coronary artery bypass grafts... περισσότερα »
Enhanced recovery programmes for the elderly
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1TlJouV via IFTTT
Targeting oliguria reversal in perioperative restrictive fluid management does not influence the occurrence of renal dysfunction: A systematic review and meta-analysis
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
[image: image]BACKGROUND: Interest in perioperative fluid restriction has increased, but it could lead to hypovolaemia. Urine output is viewed as a surrogate for renal perfusion and is frequently used to guide perioperative fluid therapy. However, the rationale behind targeting oliguria reversal – achieving and maintaining urine output above a previously defined threshold by additional fluid boluses – is often questioned. OBJECTIVE: We assessed whether restrictive fluid management had an effect on oliguria, acute renal failure (ARF) and fluid intake. We also investigated whether targ... περισσότερα »
Estimation of the minimum effective volume of 0.5% bupivacaine for ultrasound-guided axillary brachial plexus block
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
[image: image]No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1TlJqCQ via IFTTT
Preoperative hydration with 0.9% normal saline to prevent acute kidney injury after major elective open abdominal surgery: A randomised controlled trial
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
[image: image]BACKGROUND: Postoperative acute kidney injury (AKI) is the second leading cause of hospital-acquired AKI. Although many preventive strategies have been tested, none of them has been totally effective. OBJECTIVE: We investigated whether preoperative intravenous hydration with 0.9% normal saline could prevent postoperative AKI. DESIGN: Randomised controlled trial. SETTING: University Ramón y Cajal Hospital, Spain, from June 2006 to February 2011. PATIENTS: Total 328 inpatients scheduled for major elective open abdominal surgery. INTERVENTION: 0.9% normal saline at a dose... περισσότερα »
Incidence of general anaesthesia for caesarean section in parturients from different geographic regions: 7-year retrospective study in a single European university centre
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 3 δευτερόλεπτα
[image: image]No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1TlJoLj via IFTTT
Vitamin D pathway gene polymorphisms as predictors of hepatitis C virus-related mixed cryoglobulinemia
Alexandros G. SfakianakisστοEvolution of a geneΠριν από 6 δευτερόλεπτα
[image: image]Mixed cryoglobulinemia (MC) is the most frequent extrahepatic hepatitis C virus (HCV) complication. Vitamin D is a modulator of several biological processes, including immune and skeletal systems and MC presence and systemic vasculitis were associated independently with low levels of vitamin D. Considering the impact of vitamin D, we aimed to evaluate the role of some single nucleotide polymorphisms (SNPs) of vitamin D pathway genes in the prediction of MC in HCV patients treated with pegylated interferon and ribavirin. We investigated SNPs in IL-28B, CYP27B1, CYP27A1, ...περισσότερα »
Quantitation of DNA methyltransferase activity via chronocoulometry in combination with rolling chain amplification
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 19 δευτερόλεπτα
[image: alertIcon.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): Jingjing Ji, Yuanjian Liu, Wei Wei, Yuanjian Zhang, Songqin Liu In this paper, a rolling chain amplification (RCA) strategy was proposed for chronocoulometric detection of DNA methyltransferase (MTase) activity. Briefly, after the double DNA helix structure was assembled on the surface of gold electrode, it was first methylated by M. SssI MTase and then RCA was realized in the presence of E. coli and phi29 DNA polymerase. Successively, numerous hexaammineruthenium (I...περισσότερα »
A colorimetric and fluorescent probe for detecting intracellular biothiols
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 19 δευτερόλεπτα
[image: alertIcon.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): Chunyang Chen, Wei Liu, Cong Xu, Weisheng Liu A new rapid and highly sensitive coumarin-based probe (probe 1) has been designed and synthesized for detecting intracellular thiols. Probe 1 was prepared by a 4-step procedure as a latent fluorescence probe to achieve high sensitivity and fluorescence turn-on response toward cysteine and homocysteine over GSH and other various natural amino acids under physiological conditions. Owing to specific cyclization between thiol...περισσότερα »
A silicon based implantable microelectrode array for electrophysiological and dopamine recording from cortex to striatum in the non-human primate brain
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 19 δευτερόλεπτα
[image: S09565663.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): Song Zhang, Yilin Song, Mixia Wang, Zhiming Zhang, Xinyi Fan, Xianteng Song, Ping Zhuang, Feng Yue, Piu Chan, Xinxia Cai Dual-mode, multielectrode recordings have become routine in rodent neuroscience research and have recently been adapted to the non-human primate. However, robust and reliable application of acute, multielectrode recording methods in monkeys especially for deep brain nucleus research remains a challenge. In this paper, We described a low cost silico...περισσότερα »
High levels of preoperative and postoperative N terminal B-type natriuretic propeptide influence mortality and cardiovascular complications after noncardiac surgery: A prospective cohort study
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 20 δευτερόλεπτα
[image: image]BACKGROUND: Major noncardiac surgery is associated with a 5% incidence of serious cardiovascular complications and with a 1 to 2% probability of death from cardiac causes. Over the last few decades, researchers have assessed the perioperative predictive power of several risk indices. Research is currently focused on the evaluation of biomarkers. OBJECTIVES: The objective was to determine the incidence of high serum levels of N terminal B-type natriuretic propeptide (NT-proBNP) before and after surgery in adults undergoing elective major noncardiac procedures and to eva... περισσότερα »
The use of advanced airway management devices in clinical practice
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 20 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1TlJqCU via IFTTT
Intraoperative hypotension is associated with myocardial damage in noncardiac surgery: An observational study
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 20 δευτερόλεπτα
[image: image]BACKGROUND: Perioperative myocardial damage and infarction (MI) is associated with increased mortality and other postoperative complications. OBJECTIVES: To assess the incidence of perioperative myocardial damage in patients undergoing major elective noncardiac surgery, to elucidate any association with postoperative MI and mortality and to estimate the impact of preoperative risk factors and intraoperative hypotension. DESIGN: Observational cohort study. SETTING: Karolinska University Hospital, Stockholm, Sweden, from October 2012 to May 2013. PATIENTS: In this single...περισσότερα »
Perioperative Medicine for the Junior Clinician
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 20 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1TlJqCY via IFTTT
Diagnosis of Ulnar Nerve Entrapment at the Arcade of Struthers with Electromyography and Ultrasound
Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 21 δευτερόλεπτα
[image: image]Summary: Ulnar neuropathy is caused by compression of the ulnar nerve in the upper extremity, frequently occurring at the level of the elbow or wrist. Rarely, ulnar nerve entrapment may be seen proximal to the elbow. This report details a case of ulnar neuropathy diagnosed and localized to the arcade of Struthers with electromyography (EMG) and ultrasound (US) imaging and confirmed at time of operative release. US imaging and EMG findings were used to preoperatively localize the level of compression in a patient presenting with left ulnar neuropathy. In this case, ulna...περισσότερα »
Resveratrol Protects Oxidative Stress-Induced Intestinal Epithelial Barrier Dysfunction by Upregulating Heme Oxygenase-1 Expression
Alexandros G. SfakianakisστοThe OesophagusΠριν από 24 δευτερόλεπτα
Abstract Background/Aim Obstructive jaundice (OJ) is frequently complicated by infections and has been associated with increased bacterial translocation, intestinal epithelial hyperpermeability, and oxidative stress, but the mechanism remains unclear. The potential effect of resveratrol (Res) on modifying intestinal epithelial dysfunction was evaluated both in vitro and in vivo. Methods Caco-2 cells (in vitro) and male Wistar rats (*n* = 60; in vivo) were used to evaluate the role of Res on intestinal epithelial dysfunction. Hydrogen peroxide was used to induce oxidative stress in... περισσότερα »
Heterosynaptic modulation of evoked synaptic potentials in layer II of the entorhinal cortex by activation of the parasubiculum.
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
The superficial layers of the entorhinal cortex receive sensory and associational cortical inputs, and provide the hippocampus with the majority of its cortical sensory input. The parasubiculum, which receives input from multiple hippocampal subfields, sends it single major output projection to layer II of the entorhinal cortex, suggesting that it may modulate processing of synaptic inputs to the entorhinal cortex. Indeed, stimulation of the parasubiculum can enhance entorhinal responses to synaptic input from the piriform cortex in vivo. Theta EEG activity contributes to spatial ...περισσότερα »
Ubiquitin ligase Nedd4-2 modulates Kv1.3 current amplitude and ion channel protein targeting
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
Voltage-dependent potassium channels (Kv) go beyond the stabilization of the resting potential, and regulate biochemical pathways, intracellular signaling, and detect energy homeostasis. Because targeted deletion and pharmacological block of the Kv1.3 channel protein produces marked changes in metabolism, resistance to diet-induced obesity, and changes in olfactory structure and function, this investigation explored Nedd4-2-mediated ubiquitination and degradation to regulate Kv1.3 channel density. Heterologous co-expression of Nedd4-2 ligase and Kv1.3 in HEK 293 cells reduced Kv1....περισσότερα »
Sleep and Memory Consolidation: A Common Mechanism Across Species?
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
In humans, memory consolidation can be aided by the representation of an odor previously associated with target information during sleep. In an elegant study, Zwaka and colleagues have demonstrated that the same process occurs in honeybees, suggesting that the relationship between sleep and memory may be similar across different animal species. from Physiology via xlomafota13 on Inoreader http://ift.tt/24sVhKU
Spontaneous Activations Follow a Common Developmental Course Across Primary Sensory Areas in Mouse Neocortex
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
Spontaneous propagation of spiking within the local neocortical circuits in mature primary sensory areas is highly non-random, engaging specific sets of interconnected and functionally-related neurons. These spontaneous activations promise insight into neocortical structure and function, but their properties in the first two weeks of perinatal development are incompletely characterized. Previously we have found that there is a minimal numerical sample, on the order of 400 cells, necessary to fully capture mature neocortical circuit dynamics. Therefore we maximized our numerical sa... περισσότερα »
Knockout of the BK {beta}4 subunit promotes a functional coupling of BK channels and ryanodine receptors that mediate a fAHP-induced increase in excitability
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
BK channels are large conductance calcium- and voltage-activated potassium channels with diverse properties. Knockout of the accessory BK β4 subunit in hippocampus dentate gyrus granule neurons causes BK channels to change properties from slow-gated type II channels to fast-gated, type I channels that sharpen the action potential, increase the fast-afterhyperpolarization amplitude, and increase spike frequency. Here we studied the calcium channels that contribute to fast-gated BK channel activation and increased excitability of β4 knockout neurons. By utilizing pharmacological bloc...περισσότερα »
The influence of the contractile properties of muscle on motor unit firing rates during a moderate contraction intensity in vivo
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
It is suggested that firing rate characteristics of motor units (MUs) are influenced by the physical properties of the muscle. However, no study has correlated MU firing rates at recruitment, targeted force, or derecruitment with the contractile properties of the muscle in vivo. Twelve participants (age=20.67±2.35) performed a 40% isometric maximal voluntary contraction of the leg extensors that included linearly increasing, steady force, and decreasing segments. Muscle biopsies were collected with myosin heavy chain (MHC) content quantified and surface electromyography (EMG) was r...περισσότερα »
Rare human nerve growth factor beta (NGFB) mutation reveals relationship between C afferent density and acute pain evaluation.
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
The rare nerve growth factor beta (NGFB) mutation R221W causes a selective loss of thinly myelinated fibers and especially unmyelinated C-fibers. Carriers of this mutation show altered pain sensation. A subset presents with arthropathic symptoms, with the homozygous most severely affected. The aim of the present study was to investigate the relationship between peripheral afferent loss and pain evaluation by performing a quantification of small fiber density in the cornea of the carriers, relating density to pain evaluation measures. In vivo corneal confocal microscopy (CCM) was u... περισσότερα »
Brain derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
Brain-derived neurotrophic factor (BDNF) plays an important role in hippocampus-dependent learning and memory. Canonically, this has been ascribed to an enhancing effect on neuronal excitability and synaptic plasticity in the CA1 region. However, it is the pyramidal neurons in the subiculum that form the primary efferent pathways conveying hippocampal information to other areas of the brain, and yet the effect of BDNF on these neurons has remained unexplored. We present new data that BDNF regulates neuronal excitability and cellular plasticity in a much more complex manner than pr...περισσότερα »
Role of Fyn-mediated NMDA receptor function in Prediabetic Neuropathy in Mice
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
Diabetic neuropathy is a common complication of diabetes. This study evaluated the role of Fyn kinase and NMDARs in the spinal cord in diabetic neuropathy using an animal model of high-fat diet-induced prediabetes. We found that prediabetic wild-type mice exhibited tactile allodynia and thermal hypoalgesia after a 16-week high fat diet, relative to normal diet-fed wild-type mice. Furthermore, prediabetic wild-type mice exhibited increased tactile allodynia and thermal hypoalgesia at 24 weeks, relative to 16 weeks. Such phenomenon were correlated with increased expression and activ... περισσότερα »
Inhibitory Modulation of Optogenetically-Identified Neuron Subtypes in the Rostral Solitary Nucleus
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
Inhibition is presumed to play an important role in gustatory processing in the rostral nucleus of the solitary tract (rNST). One source of inhibition, GABA, is abundant within the nucleus and comes from both local, intrasolitary sources as well as from outside the nucleus. In addition to the receptor-mediated effects of GABA on rNST neurons, the hyperpolarization-sensitive currents, "Ih" and "IA", have the potential to further modulate afferent signals. In order to elucidate the effects of GABAergic modulation on solitary tract (ST) - evoked responses in phenotypically-defined rN... περισσότερα »
HCN hyperpolarization-activated cation channels strengthen virtual nicotinic EPSPs and thereby elevate synaptic amplification in rat sympathetic neurons
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
The influence of h-current (Ih) upon synaptic integration in paravertebral sympathetic neurons was studied together with expression of HCN subunit isoforms. All four HCN subunits were detected in homogenates of the rat superior cervical ganglion (SCG) using the polymerase chain reaction to detect reverse transcribed messenger RNAs (RT-PCR) and using quantitative PCR (qPCR). Voltage clamp recordings from dissociated SCG neurons at 35°C detected Ih in all cells, with a maximum h-conductance of 1.2 ± 0.1 nS, half-maximal activation at -87.6 mV and a reversal potential of -31.6 mV. In...περισσότερα »
Tooth Decay (Dental Caries)
Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
The post Tooth Decay (Dental Caries) appeared first on Family Dentistry and Cosmetic Surgery Clinic. from #Dental via xlomafota13 on Inoreader http://ift.tt/1ToiuT8 via IFTTT
Effect of Soil Type on the Fate of Kerosene Compounds in the Presence of Water and Ethanol
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 36 δευτερόλεπτα
The post Effect of Soil Type on the Fate of Kerosene Compounds in the Presence of Water and Ethanol appeared first on Welcome to Avens. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Y9Y4BE via IFTTT
Traumatic Cataract: A Review
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 36 δευτερόλεπτα
The post Traumatic Cataract: A Review appeared first on Welcome to Avens. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/26VJHXk via IFTTT
Vaccines, Vol. 4, Pages 15: Coupling Peptide Antigens to Virus-Like Particles or to Protein Carriers Influences the Th1/Th2 Polarity of the Resulting Immune Response
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 36 δευτερόλεπτα
We have conjugated the S9 peptide, a mimic of the group B streptococcal type III capsular polysaccharide, to different carriers in an effort to elicit an optimal immune response. As carriers, we utilized the soluble protein keyhole limpet hemocyanin and virus-like particles (VLPs) from two plant viruses, Cowpea Chlorotic Mottle Virus and Cowpea Mosaic Virus. […]
Study on the use of quantitative ultrasound evaluation of diabetic neuropathy in the rat sciatic nerve
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 36 δευτερόλεπτα
Abstract Ultrasound is an effective tool for peripheral disease with direct imaging of morphological and echogenic changes, but it has limitations when applied to evaluation of diabetic peripheral neuropathy. The aim of this study was to assess the role of ultrasound to quantitatively evaluate diabetic peripheral neuropathy in rat sciatic nerve. In our experiments, ultrasound […]
IJERPH, Vol. 13, Pages 469: Spatial-Temporal Epidemiology of Tuberculosis in Mainland China: An Analysis Based on Bayesian Theory
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 36 δευτερόλεπτα
Objective: To explore the spatial-temporal interaction effect within a Bayesian framework and to probe the ecological influential factors for tuberculosis. Methods: Six different statistical models containing parameters of time, space, spatial-temporal interaction and their combination were constructed based on a Bayesian framework. The optimum model was selected according to the deviance information criterion (DIC) value. […]
IJERPH, Vol. 13, Pages 466: Health-Related Quality of Life among Artisanal Fisherwomen/Shellfish Gatherers: Lower than the General Population
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 36 δευτερόλεπτα
Quality of life is an indicator of how well one perceives that he/she is functioning physically and mentally. The aim of this paper is to determine the health-related quality of life (HRQOL) of artisanal fisherwomen/shellfish gatherers from the Saubara municipality in Bahia, Brazil in comparison to the general population. A structured questionnaire was administered to […]
Urban landscape extraction and analysis based on optical and microwave ALOS satellite data
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 36 δευτερόλεπτα
Abstract Accurate mapping of urban land cover from satellite data provides essential input to urban landscape analysis, modelling and urban ecosystem studies. Additionally, analysis of urban landscape metrics will provide a positive step towards comprehensive understanding of the features of urban landscape structure and further planning. In the present study, multi-spectral Advanced Land Observing Satellite […]
Arsenic
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 36 δευτερόλεπτα
Arsenic: A metallic element that forms a number of poisonous compounds, arsenic is found in nature at low levels mostly in compounds with oxygen, chlorine, and sulfur. These are called inorganic arsenic compounds. Arsenic in plants and animals combines with carbon and hydrogen. This is called organic arsenic. Organic arsenic is usually less harmful than […]
Multiple Myeloma Mortality in Relation to Obesity Among African Americans
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 36 δευτερόλεπτα
Multiple myeloma (MM) incidence and mortality are higher among African Americans (AAs) than among other population groups. The prevalence of obesity is also elevated among AAs, but few studies have examined risk of this cancer in relation to body size among AAs. We combined data from seven prospective cohorts tracking mortality among 239 597 AA […]
Virtual Fitting, Selection, and Cutting of Preformed Anatomic Orbital Implants.
Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 40 δευτερόλεπτα
Purpose: To evaluate the usage of preoperative digital anatomic implant evaluation in internal orbital fractures. Methods: An IRB-approved review of cases of orbital fracture repair was conducted and cases where digital implant modeling was performed were selected for comprehensive review. The surgical time of these cases was also compared with surgeon and implant matched controls. Results: A total of 25 patients and 26 orbits underwent preoperative virtual fitting and were reviewed. There were no complications or revision surgeries needed. Postoperative assessment demonstrated accu...περισσότερα »
Embryologic and Fetal Development of the Human Eyelid.
Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 40 δευτερόλεπτα
Purpose: To review the recent data about eyelid morphogenesis, and outline a timeline for eyelid development from the very early stages during embryonic life till final maturation of the eyelid late in fetal life. Methods: The authors extensively review major studies detailing human embryologic and fetal eyelid morphogenesis. These studies span almost a century and include some more recent cadaver studies. Numerous studies in the murine model have helped to better understand the molecular signals that govern eyelid embryogenesis. The authors summarize the current findings in molecul... περισσότερα »
Periorbital Autologous Fat Grafting in Facial Nerve Palsy.
Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 40 δευτερόλεπτα
Purpose: To report outcomes and complications of periorbital autologous fat grafting (AFG) in improving volume loss-related symmetry and function in facial nerve palsy patients and to assess patient satisfaction. Methods: A retrospective, noncomparative review of all facial nerve palsy patients who underwent periorbital AFG at single center over a 4-year period. Two independent graders objectively assessed standard photographs for any change in volume loss and symmetry: pre- and postoperative periods (early, 0-2 months; intermediate, 3-9 months; and late, >10 months). Any adverse ou...περισσότερα »
100. Jahrestagung der Deutschen Gesellschaft für Pathologie e.V.
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 40 δευτερόλεπτα
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Tooth Decay (Dental Caries)
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 41 δευτερόλεπτα
The post Tooth Decay (Dental Caries) appeared first on Family Dentistry and Cosmetic Surgery Clinic. from #Dental via xlomafota13 on Inoreader http://ift.tt/1ToiuT8 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Increased efficacy of regularly repeated cycles with OnabotulinumtoxinA in MOH patients beyond the first year of treatment
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 44 δευτερόλεπτα
Chronic migraine is one of the most common diseases in the world and it is often associated with medication overuse that can worsen the headache itself. Thus, it is important to adopt effective therapies to re... from Cephalalgia via xlomafota13 on Inoreader http://ift.tt/1WKbZQ0 via IFTTT
End-of-life in the ICU: moving from 'withdrawal of care to a palliative care, patient-centred approach
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 48 δευτερόλεπτα
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Airway management in the critically ill: the same, but different
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 48 δευτερόλεπτα
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Green preparation of carbon dots with papaya as carbon source for effective fluorescent sensing of Iron (III) and Escherichia coli
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 52 δευτερόλεπτα
[image: S09565663.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): Ning Wang, Yiting Wang, Tingting Guo, Ting Yang, Mingli Chen, Jianhua Wang A simple one-step hydrothermal green approach was reported for the preparation of carbon dots (CDs) without any further decoration or modification with papaya powder as natural carbon source. In this economical and eco-friendly system, deionized water or 90% ethanol was used as solvent to produce water-soluble or ethanol-soluble CDs, respectively, termed as W-CDs and E-CDs. The quantum yield ...περισσότερα »
Fluorescent turn-on sensing of bacterial lipopolysaccharide in artificial urine sample with sensitivity down to nanomolar by tetraphenylethylene based aggregation induced emission molecule
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 52 δευτερόλεπτα
[image: S09565663.gif] Publication date: 15 November 2016 *Source:*Biosensors and Bioelectronics, Volume 85 Author(s): Guoyu Jiang, Jianguo Wang, Yang Yang, Guanxin Zhang, Yaling Liu, He Lin, Guilan Zhang, Yongdong Li, Xiaolin Fan A tetraphenylethylene based aggregation induced emission (AIE) probe, TPEPyE, bearing a positively charged pyridinium pendant was designed and synthesized. The positively charged TPEPyE can efficiently bind to the negatively charged lipopolysaccharide (LPS) through electrostatic interactions between the two oppositely charged species. As a result, upon the... περισσότερα »
Effect of Japanese cedar–specific sublingual immunotherapy on allergen-specific TH2 cell counts in blood
Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 1 ώρα
Publication date: Available online 4 May 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Takayasu Nomura, Motohiko Suzuki, Makoto Yokota, Yoshihisa Nakamura, Kazuyoshi Ozeki, Yasuhiko Ito, Ikuya Tsuge, Shinji Saitoh BackgroundThe contribution of antigen-specific TH cells in peripheral blood to immunologic mechanisms underlying sublingual immunotherapy (SLIT) remains unclear, partly because of the lack of a standardized method for the analysis of this rare lymphocyte subset.ObjectiveTo clarify the role of antigen-specific TH cells during SLIT using a sensitive method a...περισσότερα »
Effect of eosinophils activated with Alternaria on the production of extracellular matrix from nasal fibroblasts
Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 1 ώρα
Publication date: Available online 4 May 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Seung-Heon Shin, Mi-Kyung Ye, Sung-Yong Choi, Yee-Hyuk Kim BackgroundEosinophils and fibroblasts are known to play major roles in the pathogenesis of nasal polyps. Fungi are commonly found in nasal secretion and are associated with airway inflammation.ObjectiveTo investigate whether activated eosinophils by airborne fungi can influence the production of extracellular matrix (ECM) from nasal fibroblasts.MethodsInferior turbinate and nasal polyp fibroblasts were stimulated with Alte... περισσότερα »
Does Simulation Improve Recognition and Management of Pediatric Septic Shock, and If One Simulation Is Good, Is More Simulation Better?.
Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Objectives: Determine whether serial simulation training sessions improve resident recognition and initial septic shock management in a critically ill simulated septic shock patient, and to determine whether serial simulations further improve resident task performance when compared with a single simulation session. Design: Prospective observational cohort study with a live expert review of trainee simulation performance. Expert reviewers blinded to prior trainee performance. Setting: A PICU room in a quaternary-care children's hospital, featuring a hi-fidelity pediatric patient simu... περισσότερα »
Screening for malnutrition in patients with gastro-entero-pancreatic neuroendocrine tumours: a cross-sectional study
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Objectives To investigate whether screening for malnutrition using the validated malnutrition universal screening tool (MUST) identifies specific characteristics of patients at risk, in patients with gastro-entero-pancreatic neuroendocrine tumours (GEP-NET). Design Cross-sectional study. Setting University Hospitals Coventry & Warwickshire NHS Trust; European Neuroendocrine Tumour Society Centre of Excellence. Participants Patients with confirmed GEP-NET (n=161) of varying […]
Novel application of a discrete choice experiment to identify preferences for a national healthcare-associated infection surveillance programme: a cross-sectional study
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Objective To identify key stakeholder preferences and priorities when considering a national healthcare-associated infection (HAI) surveillance programme through the use of a discrete choice experiment (DCE). Setting Australia does not have a national HAI surveillance programme. An online web-based DCE was developed and made available to participants in Australia. Participants A sample of 184 purposively […]
Occupational outcomes following mild traumatic brain injury in Canadian military personnel deployed in support of the mission in Afghanistan: a retrospective cohort study
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Objective Deployment-related mild traumatic brain injury (MTBI) occurs in a significant number of military personnel but its long-term impacts are unclear. This study explores the impact of deployment-related MTBI on continued fitness-for-duty, with the ultimate intent of identifying potential targets for intervention to attenuate its effects. Participants Consisted of 16 193 Canadian Armed Forces (CAF) […]
A prospective study validating the EORTC QLQ-BM22 bone metastases module in patients with painful bone metastases undergoing palliative radiotherapy
Alexandros G. SfakianakisστοRathiotherapy by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 3 May 2016 *Source:*Radiotherapy and Oncology Author(s): Srinivas Raman, Keyue Ding, Edward Chow, Ralph M. Meyer, Abdenour Nabid, Pierre Chabot, Genevieve Coulombe, Shahida Ahmed, Joda Kuk, A. Rashid Dar, Aamer Mahmud, Alysa Fairchild, Carolyn F. Wilson, Jackson S.Y. Wu, Kristopher Dennis, Carlo DeAngelis, Rebecca K.S. Wong, Liting Zhu, Michael Brundage PurposeQuality of life (QOL) can be compromised in patients with bone metastases, and validated QOL instruments are required to accurately measure QOL outcomes in this population. This study investiga... περισσότερα »
Long term experience with 3D image guided brachytherapy and clinical outcome in cervical cancer patients
Alexandros G. SfakianakisστοRathiotherapy by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 2 May 2016 *Source:*Radiotherapy and Oncology Author(s): Ivone Ribeiro, Hilde Janssen, Marisol De Brabandere, An Nulens, Dominique De Bal, Ignace Vergote, Erik Van Limbergen Background and purposeTo report our 10years’ experience and learning curve of the treatment of cervical cancer patients with chemo radiotherapy and MRI (or CT in 9 selected patients) guided brachytherapy using pulsed dose rate (PDR) brachytherapy (BT).Methods and materialsHundred and seventy consecutive patients with cervical cancer FIGO stage IB–IVB (without metastases beyond th... περισσότερα »
Normal tissue complication probability (NTCP) models for late rectal bleeding, stool frequency and fecal incontinence after radiotherapy in prostate cancer patients
Alexandros G. SfakianakisστοRathiotherapy by Alexandros G. SfakianakisΠριν από 1 ώρα
Publication date: Available online 3 May 2016 *Source:*Radiotherapy and Oncology Author(s): Wouter Schaake, Arjen van der Schaaf, Lisanne V. van Dijk, Alfons H.H. Bongaerts, Alfons C.M. van den Bergh, Johannes A. Langendijk Background and purposeCurative radiotherapy for prostate cancer may lead to anorectal side effects, including rectal bleeding, fecal incontinence, increased stool frequency and rectal pain. The main objective of this study was to develop multivariable NTCP models for these side effects.Material and methodsThe study sample was composed of 262 patients with localized ...περισσότερα »
Value of knowing physical characteristics of the airway device before using it
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 2 ώρες
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Inhibiting NADPH oxidase protects against long-term memory impairment induced by neonatal sevoflurane exposure in mice
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 2 ώρες
Background Neonatal exposure to anaesthetics such as sevoflurane has been reported to result in behavioural deficits in rodents. However, while oxidative injury is thought to play an underlying pathological role, the mechanisms of neurotoxicity remain unclear. In the present study, we investigated whether the NADPH oxidase inhibitor apocynin protects against long-term memory impairment produced by neonatal sevoflurane exposure in mice. Methods Postnatal day six mice were divided into four groups; (1) non-anaesthesia, (2) intraperitoneal apocynin (50 mg kg–1) treatment, (3) 3% se... περισσότερα »
Comparison of pathogenicity prediction tools on missense variants in RYR1 and CACNA1S associated with malignant hyperthermia
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 2 ώρες
Background Malignant hyperthermia (MH) is a pharmacogenetic disorder that has been linked to the skeletal muscle calcium release channel (*RYR1*) and the α1S subunit of the voltage-dependent L-type calcium channel (*CACNA1S*). Genomic DNA capture and next generation sequencing are becoming the preferred method to identify mutations in these genes. Bioinformatic pathogenicity prediction of identified variants may help to determine if these variants are in fact disease causing. Methods Eight pathogenicity prediction programmes freely available on the web were used to determine th...περισσότερα »
Obesity in the HIV-infected population in Northeast England: a particular issue in Black-African women
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
People living with HIV are surviving longer on successful antiretroviral therapy and obesity rates are increasing. We sought to determine the prevalence of being overweight or obese in a regional population of people living with HIV and to explore the demographic and clinical characteristics associated with obesity or being overweight. Data on patients attending three […]
An audit of HIV treatment outcomes in a UK inner city cohort
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
We describe the demographics and treatment outcomes of a HIV-infected cohort from Croydon University Hospital, London, UK. We showed that the Croydon Cohort had good viral load suppression (98.6% with viral load < 100 c/ml and 99.0% with viral load < 200 c/ml) despite being a potentially challenging cohort in a deprived area of London. […]
Decline in HIV seroprevalence in street youth 2006-2012, St. Petersburg, Russia: moving toward an AIDS-free generation
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
A 2006 survey of street youth at pre-mapped street youth locations in St. Petersburg, Russia, found extremely high HIV seroprevalence (37.4%) among 313 street youth aged 15–19 years of age, strongly associated with injection drug use, which was reported by 50.6% of participants. In response, multi-sectoral social support and prevention measures were instituted. In 2012, […]
Immune-mediated reactions to vancomycin
Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 2 ώρες
Publication date: Available online 4 May 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Jasmit S. Minhas, Paige G. Wickner, Aidan A. Long, Aleena Banerji, Kimberly G. Blumenthal BackgroundVancomycin is a broad-spectrum antibiotic whose use may be limited by adverse drug reactions (ADRs). Although vancomycin toxic effects are known, there are limited data on vancomycin hypersensitivity reactions (HSRs).ObjectiveTo understand the most commonly reported vancomycin HSRs through systematic case review.MethodsWe performed a literature search for English-language case repo... περισσότερα »
A case of vibratory anaphylaxis
Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 2 ώρες
Publication date: Available online 4 May 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Mollie L. Alpern, Ronna L. Campbell, Matthew A. Rank, Miguel A. Park, John B. Hagan from Allergy\Immunology via ola Kala on Inoreader http://ift.tt/1SQcPps via IFTTT
Effect of acupuncture on house dust mite specific IgE, substance P, and symptoms in persistent allergic rhinitis
Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 2 ώρες
Publication date: Available online 4 May 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): John Leslie McDonald, Peter K. Smith, Caroline A. Smith, Charlie Changli Xue, Brenda Golianu, Allan W. Cripps BackgroundClinical evidence suggests that acupuncture improves symptoms in persistent allergic rhinitis, but the physiologic basis of these improvements is not well understood.ObjectiveA randomized, sham-controlled trial of acupuncture for persistent allergic rhinitis in adults investigated possible modulation of mucosal immune responses.MethodsA total of 151 individuals ... περισσότερα »
2016 European guideline on the management of non-gonococcal urethritis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρεS
We present the updated International Union against Sexually Transmitted Infections guideline for the management of non-gonococcal urethritis in men. This guideline recommends confirmation of urethritis in symptomatic men before starting treatment. It does not recommend testing asymptomatic men for the presence of urethritis. All men with urethritis should be tested for Chlamydia trachomatis and Neisseria […]
Staging beim Magenkarzinom
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Zusammenfassung Hintergrund Ziel in der Diagnostik des Magenkarzinoms ist eine frühzeitige Diagnose und optimale Ausbreitungsdiagnostik mit modernen bildgebenden Verfahren zur Therapieentscheidung im Rahmen operativer und multimodaler Konzepte und zur Vermeidung operativer Eingriffe in inoperablen Fällen. Fragestellung Es soll ein Überblick zum gegenwärtigen Stand der Diagnostik im TNM-Staging des Magenkarzinoms unter Einsatz moderner bildgebender Verfahren gegeben […]
Abducens palsy after temporomandibular joint arthroscopy: a rare complication
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Abstract Background Arthroscopy of the temporomandibular joint (TMJ) is a minimally invasive and safe procedure; nevertheless, some accidents and complications have been described in the literature. Case report The purpose of this article is to describe a case report of a patient that progressed to paralysis of the abducens nerve after a TMJ arthroscopy procedure. […]
A comparison of the barely Bayesian design with the triangular test for clinical trials in infectious diseases
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
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Preventing Shaken Baby Syndrome: Evaluation of a Multiple-Setting Program
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Abusive head trauma, including shaken baby syndrome, is a serious form of abuse that often results in lifelong developmental challenges or infant death. Educational programs have helped reduce the number of infants hospitalized due to abusive head trauma. The current study provides a process evaluation of Prevent Child Abuse Tennessee’s Shaken Baby Prevention Project. We […]
Antibacterial and antibiotic-modulation activity of six Cameroonian medicinal plants against Gram-negative multi-drug resistant phenotypes
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Bacterial Infections involving multi-drug resistant (MDR) phenotypes constitute a worldwide health concern. The present work was designed to assess the antibacterial properties of the methanol extracts of six … from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NY8fbZ via IFTTT
Homeopathic medical practice for anxiety and depression in primary care: the EPI3 cohort study
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
The purpose of the study was to compare utilization of conventional psychotropic drugs among patients seeking care for anxiety and depression disorders (ADDs) from general practitioners (GPs) who strictly pres… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/24z8ZbK via IFTTT
Longitudinal study of patients with chronic Chagas cardiomyopathy in Brazil (SaMi-Trop project): a cohort profile
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Purpose We have established a prospective cohort of 1959 patients with chronic Chagas cardiomyopathy to evaluate if a clinical prediction rule based on ECG, brain natriuretic peptide (BNP) levels, and other biomarkers can be useful in clinical practice. This paper outlines the study and baseline characteristics of the participants. Participants The study is being conducted […]
Orthotics and taping in the management of vertebral fractures in people with osteoporosis: a systematic review
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Objective To establish the current evidence base for the use of orthotics and taping for people with osteoporotic vertebral fracture (OVF). Design Systematic review of quantitative and qualitative studies. Data sources Medline, Medline-In Process, EMBASE, AMED, CINAHL, PEDro, TRIP, EThOS, ProQuest Dissertations and Theses and Cochrane (CDSR, DARE, CMR, HTA, EED) plus Cochrane Central, UK […]
Exploiting sensor mobility and covariance sparsity for distributed tracking of multiple sparse targets
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 2 ώρες
The problem of distributed tracking of multiple targets is tackled by exploiting sensor mobility and the presence of sparsity in the sensor data covariance matrix. Sparse matrix decomposition relying on norm-o... from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1T2vO5B via IFTTT
Realization of CUDA-based real-time registration and target localization for high-resolution video images
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 2 ώρες
Abstract High-resolution video images contain huge amount of data so that the real-time capability of image registration and target localization algorithm is difficult to be achieved when operated on central processing units (CPU). In this paper, improved ORB (Oriented FAST and Rotated BRIEF, FAST, which means "Features from Accelerated Segment Test", is a corner detection method used for feature points extraction. BRIEF means "Binary Robust Independent Elementary Features", and it's a binary bit string used to describe features) based real-time image registration and target local...περισσότερα »
The effect of standing desks on manual control in children and young adults
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 3 ώρες
Publication date: Available online 4 May 2016 *Source:*Gait & Posture Author(s): L. Britten, K. Shire, R.O. Coats, S.L. Astill The aim of the present study was to establish if and how the additional postural constraint of standing affects accuracy and precision of goal directed naturalistic actions. Forty participants, comprising 20 young adults aged 20–23 years and 20 children aged 9-10 years completed 3 manual dexterity tasks on a tablet laptop with a handheld stylus during two separate conditions [1] while standing [2] while seated. The order of conditions was counterbalanced acros... περισσότερα »
Directional acuity of whole-body perturbations during standing balance
Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 3 ώρες
Publication date: Available online 4 May 2016 *Source:*Gait & Posture Author(s): M. Jane Puntkattalee, Clarissa J. Whitmire, Alix S. Macklin, Garrett B. Stanley, Lena H. Ting The ability to perceive the direction of whole-body motion during standing may be critical to maintaining balance and preventing a fall. Our first goal was to quantify kinesthetic perception of whole-body motion by estimating directional acuity thresholds of support-surface perturbations during standing. The directional acuity threshold to lateral deviations in backward support-surface motion healthy, young adult... περισσότερα »
Real-time hardware–software embedded vision system for ITS smart camera implemented in Zynq SoC
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 3 ώρες
Abstract The article demonstrates the usefulness of heterogeneous System on Chip (SoC) devices in smart cameras used in intelligent transportation systems (ITS). In a compact, energy efficient system the following exemplary algorithms were implemented: vehicle queue length estimation, vehicle detection, vehicle counting and speed estimation (using multiple virtual detection lines), as well as vehicle type (local binary features and SVM classifier) and colour (k-means classifier and YCbCr colourspace analysis) recognition. The solution exploits the hardware–software architecture, i.... περισσότερα »
Highly Anisotropic, Highly Transparent Wood Composites
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 3 ώρες
[image: Thumbnail image of graphical abstract] *For the first time, two types of highly anisotropic, highly transparent wood composites* are demonstrated by taking advantage of the macro-structures in original wood. These wood composites are highly transparent with a total transmittance up to 90% but exhibit dramatically different optical and mechanical properties. from Biomedical Engineering via xlomafota13 on Inoreader http://ift.tt/1NY4rrc via IFTTT
Evaluation of surface water quality indices and ecological risk assessment for heavy metals in scrap yard neighbourhood
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
Pollution of surface water with heavy metals from industrial activities especially those from scrap yard has caused a major threat to human life exposing man to series of hazard, diseases, disability and conse… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1To6XmR via IFTTT
On fixed points and convergence results of sequences generated by uniformly convergent and point-wisely convergent sequences of operators in Menger probabilistic metric spaces
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
In the framework of complete probabilistic Menger metric spaces, this paper investigates some relevant properties of convergence of sequences built through sequences of operators which are either uniformly con… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1W9fgt6 via IFTTT
The existence of solutions of q-difference-differential equations
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
By using the Nevanlinna theory of value distribution, we investigate the existence of solutions of some types of non-linear q-difference differential equations. In particular, we generalize the Rellich–Wittich-ty… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1To701P via IFTTT
Retting and degumming of natural fibers by pectinolytic enzymes produced from Bacillus tequilensis SV11-UV37 using solid state fermentation
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
The present study demonstrated the simultaneous production and optimization of pectinolytic enzymes (pectate lyase and polygalacturonase) under SSF from Bacillus tequilensis SV11-UV37 using wheat bran as a substr… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1W9feRT via IFTTT
Production of a microcapsule agent of chromate-reducing Lysinibacillus fusiformis ZC1 and its application in remedi ation of chromate-spiked soil
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
Lysinibacillus fusiformis ZC1 is an efficient Cr(VI)-reducing bacterium that can transform the toxic and soluble chromate [Cr(VI)] form to the less toxic and precipitated chromite form [C… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1To6ZLq via IFTTT
Mechanism-based modeling of the clinical effects of bevacizumab and everolimus on vestibular schwannomas of patients with neurofibromatosis type 2
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
Abstract Purpose To describe the natural growth of vestibular schwannoma in patients with neurofibromatosis type 2 and to predict tumor volume evolution in patients treated with bevacizumab and everolimus. Methods Clinical data, including longitudinal tumor volumes in patients treated by bevacizumab (n = 13), everolimus (n = 7) or both (n = 2), were analyzed […]
Structure-based epitope mapping of Mycobacterium tuberculosis secretary antigen MTC28 Immunology
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
Secretary proteins of Mycobacterium tuberculosis are the key players of mycobacterial infection pathway. MTC28 is a 28kDa proline-rich secretary antigen of Mycobacterium tuberculosis and is only conserved in pathogenic strains of mycobacteria. Here we report the crystal structure of MTC28 at 2.8 and 2.15 angstrom resolutions for structure based epitope design. MTC28 shares a mog1p […]
A gene of the {beta}3-glycosyltransferase family encodes N-acetylglucosaminyltransferase II function in Trypanosoma brucei Glycobiology and Extracellular Matrices
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
The bloodstream form of the human pathogen Trypanosoma brucei expresses oligomannose, paucimannose and complex N-linked glycans, including some exceptionally large poly-N-acetyllactosamine-containing structures. Despite the presence of complex N-glycans in this organism, no homologues of the canonical N-acetylglucosaminyltransferase I or II genes can be found in the T. brucei genome. These genes encode the activities that […]
Negatively-Charged Lipids as Potential Target for New Amphiphilic Aminoglycoside Antibiotics: a biophysical study Membrane Biology
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
Bacterial membranes are highly organized containing specific microdomains which facilitate distinct protein and lipid assemblies. Evidence suggests that cardiolipin molecules segregate into such microdomains likely confering a negative curvature to the inner plasma membrane during membrane fission upon cell division. 3′,6-dinonyl neamine is an amphiphilic aminoglycoside derivative active against P. aeruginosa including strains resistant to […]
EHD3 is Required for Tubular Recycling Endosome Stabilization and an Asparagine-Glutamic Acid Residue Pair within its EH Domain Dictates its Selective Binding to NPF Peptides Membrane Biology
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
An elaborate network of dynamic lipid membranes termed tubular recycling endosomes (TRE) coordinates the process of endocytic recycling in mammalian cells. The C-terminal Eps15 homology domain-containing (EHD) proteins have been implicated in the bending and fission of TRE, thus regulating endocytic recycling. EHD proteins have an EH domain that interacts with proteins containing an asparagine-proline-phenylalanine […]
Molecular adsorption of NO on free-standing and on graphene-supported Mo 3 W 5 cluster: a density functional theory investigation
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 3 ώρες
Abstract The adsorption of molecular NO on the free-standing and graphene-supported Mo3W5 cluster is studied using methods from the gradient-corrected density functional theory. Before, the effect of the graphene support on the properties of the metal cluster was investigated. The interaction between the metal cluster and the graphene sheet takes place mainly through W atoms, which form up to three bonds with the support. Interaction energies are in the range from 0.6 to 1.5 eV. An amount of charge of about 0.4–0.5 e \(^-\) is transferred from the cluster to the support. Geometric ... περισσότερα »
Characterization and toxicological effects of three-dimensional graphene foams in rats in vivo
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 3 ώρες
Abstract Current studies have demonstrated the advantage of graphene-based materials, which suggests their potential usage for biomedical applications. However, the in vivo toxicity and performance of three-dimensional (3D) graphene foams (GFs) remain largely unclear. In the present study, we identified the short-term and long-term tissue responses to GFs or graphene oxide foams (GOFs) in a rat model of subcutaneous implantation. Results from blood biochemistry, hematological analysis, histological examination, and behavioral test all indicated nearly no noticeable in vivo toxicit... περισσότερα »
Redistribution of charged aluminum nanoparticles on oil droplets in water in response to applied electrical field
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 3 ώρες
Abstract Janus droplets with two opposite faces of different physical or chemical properties have great potentials in many fields. This paper reports a new method for making Janus droplets by covering one side of the droplet with charged nanoparticles in an externally applied DC electric field. In this paper, aluminum oxide nanoparticles on micro-sized and macro-sized oil droplets were studied. In order to control the surface area covered by the nanoparticles on the oil droplets, the effects of the concentration of nanoparticle suspension, the droplet size as well as the strength o... περισσότερα »
Site-specific in situ growth of an interferon-polymer conjugate that outperforms PEGASYS in cancer therapy
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 3 ώρες
[image: S01429612.gif] Publication date: July 2016 *Source:*Biomaterials, Volume 96 Author(s): Jin Hu, Guilin Wang, Wenguo Zhao, Xinyu Liu, Libin Zhang, Weiping Gao Conjugating poly(ethylene glycol) (PEG), PEGylation, to therapeutic proteins is widely used as a means to improve their pharmacokinetics and therapeutic potential. One prime example is PEGylated interferon-alpha (PEGASYS). However, PEGylation usually leads to a heterogeneous mixture of positional isomers with reduced bioactivity and low yield. Herein, we report site-specific in situ growth (SIG) of a PEG-like polymer, p...περισσότερα »
Nanoscale metal−organic frameworks for combined photodynamic & radiation therapy in cancer treatment
Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 3 ώρες
[image: alertIcon.gif] Publication date: August 2016 *Source:*Biomaterials, Volume 97 Author(s): Jingjing Liu, Yu Yang, Wenwen Zhu, Xuan Yi, Ziliang Dong, Xiaona Xu, Meiwan Chen, Kai Yang, Guang Lu, Lixin Jiang, Zhuang Liu Nanoscale metal organic frameworks (NMOFs) have shown great potential in biomedicine owing to their structural/chemical diversities, high molecular loading capacities, and intrinsic biodegradability. Herein, we report the rational design of a NMOF composed by hafnium (Hf4+) and tetrakis (4-carboxyphenyl) porphyrin (TCPP). In such Hf-TCPP NMOFs, while TCPP is a pho...περισσότερα »
S2k guideline on diagnosis and treatment of atopic dermatitis — short version
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
Summary Atopic dermatitis (AD) represents a pruritic, non-contagious, chronic or chronically relapsing, inflammatory skin disease. The course of the disease may be complicated by bacterial or viral superinfections. The first manifestation of the disease and further flare-ups are due to genetic predisposition and also to a variety of further trigger factors. The therapy regimen should […]
Update on the bird-egg syndrome and genuine poultry meat allergy
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 3 ώρες
Summary Allergy to poultry meat is rare and affects both children and adults. The prevalence of poultry meat allergy is unknown, but presumably is similar to that of red meat allergy. There is no close relationship between allergy to poultry meat and allergy to red meat. Poultry meat allergy may present as primary (genuine) food […]
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