Photoelectrochemical study of p-GaP(100)|ZnO|AuNP devices: strategies for enhanced electron transfer and aqueous catalysis
[image: GA?id=C6CC00703A] *Chem. Commun.*, 2016, Advance Article *DOI*: 10.1039/C6CC00703A, Communication Owen M. Williams, Justin W. Shi, Michael J. Rose We report a photocathode device consisting of GaP, a metal oxide (Al2O3 or ZnO), a phosphonate-C12-thiol monolayer, and gold nanoparticles (AuNPs). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/24RaO7q via IFTTT
Ultra low-dose VCUG in children using a modern flat detectorunit
Abstract Objectives To assess dose area products (DAP) and effective doses (ED) of voiding cystourethrography (VCUG) in children using optimized protocols on a modern flat detector unit. Methods DAP and ED were evaluated in 651 VCUG (316 girls, median age: 2.25 years) between 2009 and 2012. DAP was analyzed in relation to patient characteristics (gender, age, presence of pathological findings) and experience of performing physician using analysis of variance. ED values were estimated using adapted conversion factors from the literature. Diagnostic image quality was validated by t... περισσότερα »
Percutaneous osteosynthesis in the pelvis in cancer patients
Abstract Purpose Screw fixation (osteosynthesis) can be performed percutaneously by interventional radiologists. We report our experience in cancer patients. Material/methods We retrospectively reviewed all cases of percutaneous osteosynthesis (PO) of the pelvic ring and proximal femur performed in our hospital. PO were performed for fracture palliation or for osteolytic metastases consolidation. Screws were inserted under CT- or cone-beam CT- guidance and general anaesthesia. Patients were followed-up with pelvic-CT and medical consultation at 1 month, then every 3 months. For fr... περισσότερα »
Tomosynthesis-guided vacuum-assisted breast biopsy: A feasibility study
Abstract Purpose Evaluation of feasibility and clinical performance of a tomosynthesis-guided vacuum-assisted breast biopsy (TVAB) system compared to Stereotaxy (SVAB). Materials and methods All biopsies were performed on consecutive patients: 148 TVAB biopsies and 86 biopsies on different patients using SVAB. Evaluation criteria for each biopsy were technical feasibility, histopathology, procedure time, and complications. Results All 148 TVAB biopsies were technically successful, and gained the targeted groups of microcalcifications (100 %). In 1 of 86 SVAB procedures, it was ...περισσότερα »
Increased tumour ADC value during chemotherapy predicts improved survival in unresectable pancreatic cancer
Abstract Objectives To investigate whether changes to the apparent diffusion coefficient (ADC) of primary tumour in the early period after starting chemotherapy can predict progression-free survival (PFS) or overall survival (OS) in patients with unresectable pancreatic adenocarcinoma. Methods Subjects comprised 43 patients with histologically confirmed unresectable pancreatic cancer treated with first-line chemotherapy. Minimum ADC values in primary tumour were measured using the selected area ADC (sADC), which excluded cystic and necrotic areas and vessels, and the whole tumour ...περισσότερα »
Brain herniations into the dural venous sinus or calvarium: MRI findings, possible causes and clinical significance
Abstract Objectives To determine frequency, imaging features and clinical significance of herniations of brain parenchyma into dural venous sinuses (DVS) and/or calvarium found on MRI. Methods A total of 6160 brain MRI examinations containing at least one high-resolution T1- or T2-weighted sequence were retrospectively evaluated to determine the presence of incidental brain herniations into the DVS or calvarium. MRI sequences available for review were evaluated according to their capability to demonstrate these herniations. Patients' symptoms and clinical findings were recorded. ... περισσότερα »
Clinical role of early dynamic FDG-PET/CT for the evaluation of renal cell carcinoma
Abstract Objectives We studied the usefulness of early dynamic (ED) and whole-body (WB) FDG-PET/CT for the evaluation of renal cell carcinoma (RCC). Methods One hundred patients with 107 tumours underwent kidney ED and WB FDG-PET/CT. We visually and semiquantitatively evaluated the FDG accumulation in RCCs in the ED and WB phases, and compared the accumulation values with regard to histological type (clear cell carcinoma [CCC] vs. non-clear cell carcinoma [N-CCC]), the TNM stage (high stage [3–4] vs. low stage [1–2]), the Fuhrman grade (high grade [3–4] vs. low grade [1–2]) and p... περισσότερα »
CT pre-operative planning of a new semi-implantable bone conduction hearing device
Abstract Purpose Accommodating a novel semi-implantable bone conduction hearing device within the temporal bone presents challenges for surgical planning. This study describes the utility of CT in pre-operative assessment of such an implant. Methods Retrospective review of pre-operative CT, clinical and surgical records of 16 adults considered for device implantation. Radiological suitability was assessed on CT using 3D simulation software. Antero-posterior (AP) dimensions of the mastoid bone and minimum skull thickness were measured. CT planning results were correlated with oper...περισσότερα »
Comparison of the diagnostic performance of digital breast tomosynthesis and magnetic resonance imaging added to digital mammography in women with known breast cancers
Abstract Objectives To compare the diagnostic performance of digital breast tomosynthesis (DBT) and magnetic resonance imaging (MRI) added to mammography in women with known breast cancers. Methods Three radiologists independently reviewed image sets of 172 patients with 184 cancers; mammography alone, DBT plus mammography and MRI plus mammography, and scored for cancer probability using the Breast Imaging Reporting and Data System (BI-RADS). Jack-knife alternative free-response receiver-operating characteristic (JAFROC), which allows diagnostic performance estimation using singl... περισσότερα »
Predictive factors for complete response of chemoembolization with drug-eluting beads (DEB-TACE) for hepatocellular carcinoma
Abstract Objectives To identify clinical and imaging features associated with complete response (CR) to first session of transarterial chemoembolization (TACE) with drug-eluting beads (DEB) in patients with hepatocellular carcinoma. Methods In this prospective historical cohort, 172 patients with 315 tumours who received at least one DEB-TACE from 2007 to 2013 were studied. Imaging response was evaluated according to the modified Response Evaluation Criteria in Solid Tumours (mRECIST). Age, gender, aetiology of cirrhosis, Child and BCLC scores, particles size, location in the live... περισσότερα »
Prospective Comparison between two different magnetic resonance defecography techniques for evaluating pelvic floor disorders: air-balloon versus gel for rectal filling
Abstract Purpose to prospectively compare two rectal filling techniques for dynamic MRI of pelvic floor disorders (PFD). Methods and materials Twenty-six patients with PFD underwent the two techniques during the same procedure, one based on rectal placement of a balloon-catheter filled with saline and air insufflation (air-balloon technique or AB); another based on rectal filling with 180 cc of gel (gel-filling technique or GF). The examinations were compared for assessment and staging of PFD, including rectal-descent, rectocele, cystocele, colpocele, enterocele, rectal invaginat... περισσότερα »
Contrast-enhanced dual energy mammography with a novel anode/filter combination and artifact reduction: a feasibility study
Abstract Objectives To demonstrate the feasibility of contrast-enhanced dual-energy mammography (CEDEM) using titanium (Ti) filtering at 49 kVp for high-energy images and a novel artefact reducing image-subtraction post-processing algorithm. Methods Fifteen patients with suspicious findings (ACR BI-RADS 4 and 5) detected with digital mammography (MG) that required biopsy were included. CEDEM examinations were performed on a modified prototype machine. Acquired HE and low-energy raw data images were registered non-rigidly to compensate for possible subtle tissue motion. Subtracted ... περισσότερα »
Intravoxel incoherent motion magnetic resonance imaging to predict vesicoureteral reflux in children with urinary tract infection
Abstract Objectives To compare the diffusion parameters of intravoxel incoherent motion (IVIM) diffusion-weighted imaging (DWI) between the "reflux" and the "non-reflux" kidneys, and to evaluate the feasibility of using IVIM DWI to predict vesicoureteral reflux (VUR) in children with a urinary tract infection (UTI). Methods Eighty-three kidneys from 57 pediatric patients with a UTI were classified into "reflux" and "non-reflux" groups according to voiding cystourethrography (VCUG) results. The apparent diffusion coefficient (ADC), true diffusion coefficient (D), pseudo-diffusion ... περισσότερα »
The impact of MRI combined with visual rating scales on the clinical diagnosis of dementia: a prospective study
Abstract Objectives Dementia is foremost a clinical diagnosis. However, in diagnosing dementia, it is advocated to perform at least one neuroimaging study. This has two purposes: to rule out potential reversible dementia (PRD), and to help determine the dementia subtype. Our first goal was to establish if MRI combined with visual rating scales changes the clinical diagnosis. The second goal was to demonstrate if MRI contributes to a geriatrician's confidence in the diagnosis. Methods The dementia subtype was determined prior to and after MRI. Scoring scales used were: global cort...περισσότερα »
Ultrasound-guided percutaneous fine-needle aspiration of solid pancreatic neoplasms: 10-year experience with more than 2,000 cases and a review of the literature
Abstract Objectives To evaluate the diagnostic accuracy and complication rate of percutaneous ultrasound-guided fine-needle aspiration (US-FNA) of solid pancreatic neoplasms through the analysis of 10-year experiences of two centres. Methods Clinical, radiological and pathologic data of 2,024 patients with solid pancreatic masses who underwent US-FNAs were retrospectively evaluated. Indications for aspiration were: unresectable lesions before neo-adjuvant therapy; doubtful imaging findings; and suspicion of uncommon neoplasms with prognostic or therapeutic implications such as met...περισσότερα »
The application of platelet rich plasma in the treatment of deep dermal burns: A randomized, double blind, intra-patient controlled study
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
Abstract Platelet rich plasma (PRP) is a fraction of blood with a platelet concentration above baseline. When platelets get activated, growth factors involved in wound healing are released. The application of PRP has shown good results in wound care, however up to date no substantial research has been performed on the effect of PRP in […]
“Comparison of guidelines for venous leg ulcer diagnosis and management”
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 4 δευτερόλεπτα
from Aesthetic via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZIkpXd via IFTTT
Autophagy: Inflammatory pathology of Fanconi anaemia.
*Autophagy: Inflammatory pathology of Fanconi anaemia.* Nat Rev Mol Cell Biol. 2016 May 11; Authors: Minton K PMID: 27165789 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/21ZR4cF via IFTTT
Loss of Chromosome 8p Governs Tumor Progression and Drug Response by Altering Lipid Metabolism.
*Loss of Chromosome 8p Governs Tumor Progression and Drug Response by Altering Lipid Metabolism.* Cancer Cell. 2016 May 9;29(5):751-66 Authors: Cai Y, Crowther J, Pastor T, Abbasi Asbagh L, Baietti MF, De Troyer M, Vazquez I, Talebi A, Renzi F, Dehairs J, Swinnen JV, Sablina AA Abstract Large-scale heterozygous deletions are a hallmark of cancer genomes. The concomitant loss of multiple genes creates vulnerabilities that are impossible to reveal through the study of individual genes. To delineate the functional outcome of chromosome 8p loss of heterozygosity (LOH), a common aberr...περισσότερα »
Treatment outcome of ion beam therapy in eight patients with head and neck cancers.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
*Treatment outcome of ion beam therapy in eight patients with head and neck cancers.* Eur Arch Otorhinolaryngol. 2016 May 11; Authors: Ohkubo JI, Hohchi N, Takeuchi S, Ikezaki S, Kise Y, Koizumi H, Suzuki H Abstract Ion beam therapy has enabled us to treat formerly untreatable malignant tumors. The aim of the present study was to investigate the long-term follow-up course of patients with head and neck cancers who received ion beam therapy. The subjects were 8 patients (3 men and 5 women aged 43-78 years) with head and neck cancers who visited our department from 2006 to 2015 an...περισσότερα »
Intraoperative Endovascular Embolization of Middle Meningeal Artery and a Pseudoaneurysm by Using N-Butyl 2-Cyanoacrylate for Hemostasis during Operation of Acute Epidural Hemorrhage.
*Intraoperative Endovascular Embolization of Middle Meningeal Artery and a Pseudoaneurysm by Using N-Butyl 2-Cyanoacrylate for Hemostasis during Operation of Acute Epidural Hemorrhage.* Korean J Neurotrauma. 2015 Oct;11(2):167-169 Authors: Kim DH, Lee JY, Jeon HJ, Cho BM, Park SH, Oh SM Abstract A 21-year-old female presented with acute epidural hemorrhage (EDH) on the left temporal region associated with skull fracture after traffic accident. She was neurologically deteriorated at four-hour after an admission, and follow-up computed tomography revealed increased amount of EDH. Un... περισσότερα »
The orbitozygomatic stich: A technical modification of the lateral supraorbital approach.
*The orbitozygomatic stich: A technical modification of the lateral supraorbital approach.* Surg Neurol Int. 2016;7:46 Authors: Lazukova M, Andrade-Barazarte H, Makhamov M, Kivelev J, Goehre F, Jahromi BR, Ibrahim TF, Araujo R, Lehto H, Hernesniemi JA Abstract BACKGROUND: The lateral supraorbital approach (LSO) provides access to a variety of pathologies including anterior and some posterior circulation aneurysms, sellar and suprasellar lesions, and anterior fossa tumors. Technical modifications of LSO improve the surgical exposure of the skull base. METHODS: We retrospectively a...περισσότερα »
Notch signaling is active in normal mouse middle ear epithelial cells.
*Notch signaling is active in normal mouse middle ear epithelial cells.* Exp Ther Med. 2016 May;11(5):1661-1667 Authors: Liu X, Sheng HB, Ma R, Yang JM, Luo WW, Yang XY, Ren DD, Chi FL Abstract Mucous cell metaplasia/hyperplasia in the middle ear epithelium is associated with the occurrence of otitis media with effusion during infections. However, the mechanism by which Notch signaling regulates cell fate in the middle ear epithelium is unclear. The aim of the present study was to elucidate this mechanism by investigating the localization of Notch receptors, such as Notch1 and Not...περισσότερα »
Epiglottic cysts in clinical practice.
*Epiglottic cysts in clinical practice.* Cleve Clin J Med. 2016 May;83(5):338-339 Authors: Vourexakis Z PMID: 27168507 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/23JPnQ2 via IFTTT
Treatment outcome of ion beam therapy in eight patients with head and neck cancers.
*Treatment outcome of ion beam therapy in eight patients with head and neck cancers.* Eur Arch Otorhinolaryngol. 2016 May 11; Authors: Ohkubo JI, Hohchi N, Takeuchi S, Ikezaki S, Kise Y, Koizumi H, Suzuki H Abstract Ion beam therapy has enabled us to treat formerly untreatable malignant tumors. The aim of the present study was to investigate the long-term follow-up course of patients with head and neck cancers who received ion beam therapy. The subjects were 8 patients (3 men and 5 women aged 43-78 years) with head and neck cancers who visited our department from 2006 to 2015 an...περισσότερα »
Primary Lymphomas of the Skull Base from a Neurosurgical Perspective: Review of the Literature and Personal Experience.
*Primary Lymphomas of the Skull Base from a Neurosurgical Perspective: Review of the Literature and Personal Experience.* J Neurol Surg A Cent Eur Neurosurg. 2016 May 11; Authors: Pesce A, Acqui M, Cimatti M, Caruso R, Wierzbicki V, Raco A Abstract Primary lymphomas of the skull base are exceedingly rare and thus not commonly dealt with in everyday clinical practice. Primary diffuse large B cell lymphoma is the most commonly found (30-40% of primary non-Hodgkin lymphomas of the bone). This article reports a case of primary lymphoma of the skull base and reviews all the relevant li... περισσότερα »
Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.
*Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Patel TD, Vázquez A, Marchiano E, Sanghvi S, Eloy JA, Baredes S, Park RC Abstract OBJECTIVE/HYPOTHESIS: The aim of this population-based study is to analyze the survival benefits of elective neck dissection (END) over neck observation in T1/T2N0M0 oral tongue squamous cell carcinoma (OT-SCC) cases. STUDY DESIGN: Retrospective administrative database analysis. SUBJECTS AND METHODS: The SEER database (Surveillance, Epi... περισσότερα »
Closure of endoscopic third ventriculostomy after surgery for posterior cranial fossa tumor: The "snow globe effect".
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Closure of endoscopic third ventriculostomy after surgery for posterior cranial fossa tumor: The "snow globe effect".* Br J Neurosurg. 2015 Jun;29(3):386-9 Authors: Tamburrini G, Frassanito P, Bianchi F, Massimi L, Di Rocco C, Caldarelli M Abstract The management of obstructive hydrocephalus associated to posterior cranial fossa tumor remains a controversial issue. In this context, the role of endoscopic third ventriculostomy (ETV) performed before tumor removal (the so-called preoperative ETV) is debated and its success rat... περισσότερα »
Median maxillary alveolar osteolytic lesion in a 50-year-old female.
*Median maxillary alveolar osteolytic lesion in a 50-year-old female.* Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Apr 16; Authors: Elo JA, Sun HB, Kang SY PMID: 27165482 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/24Rc9va via IFTTT
99mTc-DMSA planar imaging versus dual-detector SPECT for the detection of renal cortical scars in patients with CKD-3.
*99mTc-DMSA planar imaging versus dual-detector SPECT for the detection of renal cortical scars in patients with CKD-3.* Nucl Med Commun. 2016 May 10; Authors: Tripathi M, Agarwal KK, Mukherjee A, Thukral P, Damle NA, Shamim SA, Mahajan S, Bagchi S, Bal C Abstract OBJECTIVE: The aim of this study was to compare planar technetium-99m-dimercaptosuccinic acid (Tc-DMSA) cortical scintigraphy with Tc-DMSA single-photon emission computed tomography (SPECT) for the detection of renal cortical scars in patients with chronic kidney disease stage-3 (CKD-3). PATIENTS AND METHODS: Data of 40... περισσότερα »
High Definition Fiber Tractography in the Evaluation and surgical planning of Lhermitte-Duclos Disease: a Case Report.
*High Definition Fiber Tractography in the Evaluation and surgical planning of Lhermitte-Duclos Disease: a Case Report.* World Neurosurg. 2016 May 7; Authors: Fernandes-Cabral DT, Zenonos GA, Hamilton RL, Panesar SS, Fernandez-Miranda JC Abstract BACKGROUND: Pre-operative delineation of normal tissue displacement patterns in Lhermitte-Duclos disease has not been feasible with conventional imaging means, surgical resection of this type of lesions remains challenging, since the boundaries of the lesion are indistinguishable during surgery. CASE DESCRIPTION: The clinical presentatio...περισσότερα »
Reversibility of neuropathology and motor deficits in an inducible mouse model for FXTAS.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Reversibility of neuropathology and motor deficits in an inducible mouse model for FXTAS.* Hum Mol Genet. 2015 Sep 1;24(17):4948-57 Authors: Hukema RK, Buijsen RA, Schonewille M, Raske C, Severijnen LA, Nieuwenhuizen-Bakker I, Verhagen RF, van Dessel L, Maas A, Charlet-Berguerand N, De Zeeuw CI, Hagerman PJ, Berman RF, Willemsen R Abstract Fragile X-associated tremor/ataxia syndrome (FXTAS) is a late-onset neurodegenerative disorder affecting carriers of the fragile X-premutation, who have an expanded CGG repeat ...περισσότερα »
Cerebral β-Amyloidosis in Mice Investigated by Ultramicroscopy.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Cerebral β-Amyloidosis in Mice Investigated by Ultramicroscopy.* PLoS One. 2015;10(5):e0125418 Authors: Jährling N, Becker K, Wegenast-Braun BM, Grathwohl SA, Jucker M, Dodt HU Abstract Alzheimer´s disease (AD) is the most common neurodegenerative disorder. AD neuropathology is characterized by intracellular neurofibrillary tangles and extracellular β-amyloid deposits in the brain. To elucidate the complexity of AD pathogenesis a variety of transgenic mouse models have been generated. A... περισσότερα »
The use of dynamic O-(2-18F-fluoroethyl)-l-tyrosine PET in the diagnosis of patients with progressive and recurrent glioma.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *The use of dynamic O-(2-18F-fluoroethyl)-l-tyrosine PET in the diagnosis of patients with progressive and recurrent glioma.* Neuro Oncol. 2015 Sep;17(9):1293-300 Authors: Galldiks N, Stoffels G, Filss C, Rapp M, Blau T, Tscherpel C, Ceccon G, Dunkl V, Weinzierl M, Stoffel M, Sabel M, Fink GR, Shah NJ, Langen KJ Abstract BACKGROUND: We evaluated the diagnostic value of static and dynamic O-(2-[(18)F]fluoroethyl)-L-tyrosine ((18)F-FET) PET parameters in patients with progressive or recurrent glioma. METHODS: We ret... περισσότερα »
Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Prognostic quality of activating TERT promoter mutations in glioblastoma: interaction with the rs2853669 polymorphism and patient age at diagnosis.* Neuro Oncol. 2015 Sep;17(9):1231-40 Authors: Spiegl-Kreinecker S, Lötsch D, Ghanim B, Pirker C, Mohr T, Laaber M, Weis S, Olschowski A, Webersinke G, Pichler J, Berger W Abstract BACKGROUND: Expression of the telomerase reverse transcriptase (TERT) might be altered by activating mutations of the rs2853669 polymorphism within the promoter region. Here we investigate th... περισσότερα »
Risk factors for deterioration of long-term liver function after radiofrequency ablation therapy.
*Risk factors for deterioration of long-term liver function after radiofrequency ablation therapy.* World J Hepatol. 2016 May 8;8(13):597-604 Authors: Honda K, Seike M, Oribe J, Endo M, Arakawa M, Syo H, Iwao M, Tokoro M, Nishimura J, Mori T, Yamashita T, Fukuchi S, Muro T, Murakami K Abstract AIM: To identify factors that influence long-term liver function following radiofrequency ablation (RFA) in patients with viral hepatitis-related hepatocellular carcinoma. METHODS: A total of 123 patients with hepatitis B virus- or hepatitis C virus-related hepatocellular car-cinoma (HCC) (n... περισσότερα »
Management of hepatocellular carcinoma: An overview of major findings from meta-analyses.
*Management of hepatocellular carcinoma: An overview of major findings from meta-analyses.* Oncotarget. 2016 May 4; Authors: Qi X, Zhao Y, Li H, Guo X, Han G Abstract This paper aims to systematically review the major findings from meta-analyses comparing different treatment options for hepatocellular carcinoma (HCC). A total of 153 relevant papers were searched via the PubMed, EMBASE, and Cochrane library databases. They were classified according to the mainstay treatment modalities (i.e., liver transplantation, surgical resection, radiofrequency ablation, transarterial emboliz...περισσότερα »
Impact of irrigation flow rate and intra-pericardial fluid on cooled-tip epicardial radiofrequency ablation.
*Impact of irrigation flow rate and intra-pericardial fluid on cooled-tip epicardial radiofrequency ablation.* Heart Rhythm. 2016 May 7; Authors: Aryana A, O'Neill PG, Pujara DK, Singh SK, Bowers MR, Allen SL, d'Avila A Abstract BACKGROUND: The optimal irrigation flow rate (IFR) during epicardial radiofrequency (RF) ablation has not been established. OBJECTIVE: This study specifically examined the impact of IFR and intra-pericardial fluid (IPF) accumulation during epicardial RF ablation. METHODS: Altogether, 452 ex vivo RF applications (10 g, 60 sec) delivered to the epicardial su... περισσότερα »
Renal denervation with standard radiofrequency ablation catheter is effective in 24-hour ambulatory blood pressure reduction - follow-up at 1/3/6/12 months.
*Renal denervation with standard radiofrequency ablation catheter is effective in 24-hour ambulatory blood pressure reduction - follow-up at 1/3/6/12 months.* Neth Heart J. 2016 May 10; Authors: Prochnau D, Otto S, Figulla HR, Surber R Abstract AIMS: To examine the effect of renal denervation (RDN) on 24‑h ambulatory blood pressure (ABP) with a standard radiofrequency ablation catheter (RF catheter). METHODS: Seventy-five patients with resistant hypertension received bilateral RDN with an RF catheter (6 RF applications, 1 minute each, 8-12 watts). Seventy patients fulfilled inclu...περισσότερα »
Median maxillary alveolar osteolytic lesion in a 50-year-old female.
*Median maxillary alveolar osteolytic lesion in a 50-year-old female.* Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Apr 16; Authors: Elo JA, Sun HB, Kang SY PMID: 27165482 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/24Rc9va via IFTTT
Complex influence of gonadotropins and sex steroid hormones on QT interval duration.
*Complex influence of gonadotropins and sex steroid hormones on QT interval duration.* J Clin Endocrinol Metab. 2016 May 11;:jc20161877 Authors: Abehsira G, Bachelot A, Badilini F, Koehl L, Lebot M, Favet C, Touraine P, Funck-Brentano C, Salem JE Abstract CONTEXT: QT interval duration is longer in women than in men. Sex steroid hormones have inconsistently been suggested to explain this difference. Implication of gonadotropins has never been studied. OBJECTIVE: We here report the combined influence of sex steroid hormones and gonadotropins on QT interval duration in healthy subjec... περισσότερα »
Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
*Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Patel TD, Vázquez A, Marchiano E, Sanghvi S, Eloy JA, Baredes S, Park RC Abstract OBJECTIVE/HYPOTHESIS: The aim of this population-based study is to analyze the survival benefits of elective neck dissection (END) over neck observation in T1/T2N0M0 oral tongue squamous cell carcinoma (OT-SCC) cases. STUDY DESIGN: Retrospective administrative database analysis. SUBJECTS AND METHODS: The SEER database (Surveillance, Epi... περισσότερα »
Treatment outcome of ion beam therapy in eight patients with head and neck cancers.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
*Treatment outcome of ion beam therapy in eight patients with head and neck cancers.* Eur Arch Otorhinolaryngol. 2016 May 11; Authors: Ohkubo JI, Hohchi N, Takeuchi S, Ikezaki S, Kise Y, Koizumi H, Suzuki H Abstract Ion beam therapy has enabled us to treat formerly untreatable malignant tumors. The aim of the present study was to investigate the long-term follow-up course of patients with head and neck cancers who received ion beam therapy. The subjects were 8 patients (3 men and 5 women aged 43-78 years) with head and neck cancers who visited our department from 2006 to 2015 an...περισσότερα »
Predicting stroke volume and arterial pressure fluid responsiveness in liver cirrhosis patients using dynamic preload variables: A prospective study of diagnostic accuracy.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
BACKGROUND: Predicting whether a fluid challenge will elicit 'fluid responsiveness' in stroke volume (SV) and arterial pressure is crucial for managing hypovolaemia and hypotension. Pulse pressure variation (PPV), SV variation (SVV) and the plethysmographic variability index (PVI) have been shown to predict SV fluid responsiveness, and the PPV/SVV ratio has been shown to predict arterial pressure fluid responsiveness under various conditions. However, these variables have not been investigated in liver cirrhosis patients. OBJECTIVE: The objective was to evaluate SV and arterial pres... περισσότερα »
Association between SNP309 and del1518 Polymorphism in MDM2 Homologue and Esophageal Squamous Cell Carcinoma Risk in Chinese Population of Shandong Province.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Association between SNP309 and del1518 Polymorphism in MDM2 Homologue and Esophageal Squamous Cell Carcinoma Risk in Chinese Population of Shandong Province.* Ann Clin Lab Sci. 2015;45(4):433-7 Authors: Zhang L, Zhu Z, Wu H, Wang K Abstract BACKGROUND: Murine double-minute 2 homologue (MDM2) is a key negative regulator of p53. Polymorphisms in the promoter region were shown to alter the gene activity and/or function, suggesting a possible role in carcinogenesis. OBJECTIVE AND METHOD: The current study aims to inv...περισσότερα »
HPLC-MS-MS Method Development and Validation of Antileishmanial Agent, S010-0269, in Hamster Serum.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *HPLC-MS-MS Method Development and Validation of Antileishmanial Agent, S010-0269, in Hamster Serum.* J Chromatogr Sci. 2015 Oct;53(9):1542-8 Authors: Sharma A, Jaiswal S, Shukla M, Sharma M, Chauhan PM, Rangaraj N, Vaghasiya K, Lal J Abstract A rapid, sensitive and simple high-performance liquid chromatography-tandem mass spectrometry method was developed and validated for the quantification of the antileishmanial agent, S010-0269, in hamster serum. A Discovery HS C-18 column (5 μm, 50 × 4.6 mm) maintained at 40°C... περισσότερα »
Complex influence of gonadotropins and sex steroid hormones on QT interval duration.
*Complex influence of gonadotropins and sex steroid hormones on QT interval duration.* J Clin Endocrinol Metab. 2016 May 11;:jc20161877 Authors: Abehsira G, Bachelot A, Badilini F, Koehl L, Lebot M, Favet C, Touraine P, Funck-Brentano C, Salem JE Abstract CONTEXT: QT interval duration is longer in women than in men. Sex steroid hormones have inconsistently been suggested to explain this difference. Implication of gonadotropins has never been studied. OBJECTIVE: We here report the combined influence of sex steroid hormones and gonadotropins on QT interval duration in healthy subjec... περισσότερα »
Reference values for insulin-like growth factor I (IGF-I) serum concentrations: comparison of six immunoassays.
*Reference values for insulin-like growth factor I (IGF-I) serum concentrations: comparison of six immunoassays.* J Clin Endocrinol Metab. 2016 May 11;:jc20161257 Authors: Chanson P, Arnoux A, Mavromati M, Brailly-Tabard S, Massart C, Young J, Piketty ML, Souberbielle JC, VARIETE Investigators Abstract CONTEXT: Measurement of IGF-I is essential for diagnosis and management of patientswith disorders affecting the somatotropic axis. However, even when IGF-I kit manufacturers follow recent consensus guidelines, different kits can give very different results for a given sample. OBJECT...περισσότερα »
Clinical, genetic and biochemical characteristics of early-onset diabetes in the Finnish population.
*Clinical, genetic and biochemical characteristics of early-onset diabetes in the Finnish population.* J Clin Endocrinol Metab. 2016 May 11;:jc20154296 Authors: Hanna H, Päivi M, Jorma I, Päivi N, Riitta V, Päivi K, Kirsti NS, Jagadish V, Joose R, Alena S, Jonna M, Teemu K, Mikael K, Timo O, Markku L Abstract CONTEXT: Major advances have been made in the classification and genetics of monogenic diabetes in infancy. OBJECTIVE: To characterize different forms of diabetes diagnosed during the first year of life. DESIGN: Patients diagnosed with diabetes before the age of one year in te...περισσότερα »
Impaired auditory selective attention ameliorated by cognitive training with graded exposure to noise in patients with traumatic brain injury.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Impaired auditory selective attention ameliorated by cognitive training with graded exposure to noise in patients with traumatic brain injury.* Neuropsychologia. 2015 Aug;75:74-87 Authors: Dundon NM, Dockree SP, Buckley V, Merriman N, Carton M, Clarke S, Roche RA, Lalor EC, Robertson IH, Dockree PM Abstract Patients who suffer traumatic brain injury frequently report difficulty concentrating on tasks and completing routine activities in noisy and distracting environments. Such impairments can have long-term negativ... περισσότερα »
Spatial Mapping in the Rat Olfactory Bulb by Odor and Direct Electrical Stimulation.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Spatial Mapping in the Rat Olfactory Bulb by Odor and Direct Electrical Stimulation. Otolaryngol Head Neck Surg. 2016 May 10; Authors: Coelho DH, Costanzo RM Abstract OBJECTIVES: To directly measure the spatial mapping in the olfactory bulb by odor presentation and by direct electrical stimulation. STUDY DESIGN: Experimental (animal). SETTING: University research laboratory. SUBJECTS AND […]
Impact of Middle versus Inferior Total Turbinectomy on Nasal Aerodynamics.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Impact of Middle versus Inferior Total Turbinectomy on Nasal Aerodynamics. Otolaryngol Head Neck Surg. 2016 May 10; Authors: Dayal A, Rhee JS, Garcia GJ Abstract OBJECTIVES: This computational study aims to (1) use virtual surgery to theoretically investigate the maximum possible change in nasal aerodynamics after turbinate surgery, (2) quantify the relative contributions of the […]
Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis. Otolaryngol Head Neck Surg. 2016 May 10; Authors: Patel TD, Vázquez A, Marchiano E, Sanghvi S, Eloy JA, Baredes S, Park RC Abstract OBJECTIVE/HYPOTHESIS: The aim of this population-based study is to analyze the survival benefits of elective neck dissection […]
Metastases of head and neck squamous cell carcinoma to soft tissue of fingertips.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Metastases of head and neck squamous cell carcinoma to soft tissue of fingertips. Indian J Med Paediatr Oncol. 2016 Apr-Jun;37(2):122 Authors: Shetty N, Sameer MS, Fernandes H, Shet D PMID: 27168713 [PubMed – as supplied by publisher] from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1XmG2xC via IFTTT
Incidence of bone metastasis in carcinoma buccal mucosa.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 19 δευτερόλεπτα
Incidence of bone metastasis in carcinoma buccal mucosa. Indian J Med Paediatr Oncol. 2016 Apr-Jun;37(2):70-73 Authors: Bhandari V Abstract INTRODUCTION: Head and neck cancer is a leading health problem in India due to the habit of chewing tobacco and bad oral and dental hygiene. Carcinoma buccal mucosa is more common and is 2.5% of all […]
Pretreatment Hematologic Findings as Novel Predictive Markers for Facial Palsy Prognosis.
*Pretreatment Hematologic Findings as Novel Predictive Markers for Facial Palsy Prognosis.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Wasano K, Kawasaki T, Yamamoto S, Tomisato S, Shinden S, Ishikawa T, Minami S, Wakabayashi T, Ogawa K Abstract OBJECTIVE: To examine the relationship between prognosis of 2 different facial palsies and pretreatment hematologic laboratory values. STUDY DESIGN: Multicenter case series with chart review. SETTING: Three tertiary care hospitals. SUBJECTS AND METHODS: We examined the clinical records of 468 facial palsy patients who were treated wi... περισσότερα »
Spatial Mapping in the Rat Olfactory Bulb by Odor and Direct Electrical Stimulation.
*Spatial Mapping in the Rat Olfactory Bulb by Odor and Direct Electrical Stimulation.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Coelho DH, Costanzo RM Abstract OBJECTIVES: To directly measure the spatial mapping in the olfactory bulb by odor presentation and by direct electrical stimulation. STUDY DESIGN: Experimental (animal). SETTING: University research laboratory. SUBJECTS AND METHODS: Odor (n = 8) and electrical stimulation (n = 4) of the olfactory bulb in rats were used to demonstrate the spatial mapping of neural responses in the olfactory bulb. Both multiunit respo...περισσότερα »
Impact of Middle versus Inferior Total Turbinectomy on Nasal Aerodynamics.
*Impact of Middle versus Inferior Total Turbinectomy on Nasal Aerodynamics.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Dayal A, Rhee JS, Garcia GJ Abstract OBJECTIVES: This computational study aims to (1) use virtual surgery to theoretically investigate the maximum possible change in nasal aerodynamics after turbinate surgery, (2) quantify the relative contributions of the middle and inferior turbinates to nasal resistance and air conditioning, and (3) quantify to what extent total turbinectomy impairs the nasal air-conditioning capacity. STUDY DESIGN: Virtual surgery and ... περισσότερα »
Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.
*Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Patel TD, Vázquez A, Marchiano E, Sanghvi S, Eloy JA, Baredes S, Park RC Abstract OBJECTIVE/HYPOTHESIS: The aim of this population-based study is to analyze the survival benefits of elective neck dissection (END) over neck observation in T1/T2N0M0 oral tongue squamous cell carcinoma (OT-SCC) cases. STUDY DESIGN: Retrospective administrative database analysis. SUBJECTS AND METHODS: The SEER database (Surveillance, Epi... περισσότερα »
Predictors of survival in parotid adenocarcinoma not otherwise specified: a National Cancer Database study of 3155 patients.
*Predictors of survival in parotid adenocarcinoma not otherwise specified: a National Cancer Database study of 3155 patients.* Head Neck. 2016 May 10; Authors: Zhan KY, Huang AT, Khaja SF, Bell D, Day TA Abstract BACKGROUND: Parotid adenocarcinoma not otherwise specified (PANOS) is a common parotid cancer, but studies specifically on this subject are limited. METHODS: We conducted a retrospective review of the National Cancer Database. RESULTS: Ten percent of all parotid cancers were PANOS (n = 3155). Median age was 67 years. Most patients were men (62.8%) with high-grade histology... περισσότερα »
Erratum.
*Erratum.* Head Neck. 2016 Jun;38(6):939 Authors: Prisman E, Haerle SK, Irish JC, Daly M, Miles B, Chan HH PMID: 27166754 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1TRjH8p via IFTTT
Head & Neck Special online-only issue, April 2016 Volume 38/Number S1.
*Head & Neck Special online-only issue, April 2016 Volume 38/Number S1.* Head Neck. 2016 Jun;38(6):807-809 Authors: PMID: 27166753 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1UVb5zW via IFTTT
Surviving Primary Pancreatic Squamous Cell Carcinoma: A Rare Entity.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Related Articles *Surviving Primary Pancreatic Squamous Cell Carcinoma: A Rare Entity.* J Gastrointest Cancer. 2015 Sep;46(3):301-3 Authors: Klair JS, Kaur H, Vaid A, Rego R PMID: 25792485 [PubMed - indexed for MEDLINE] from squamous cell carcinoma via ok on Inoreader http://ift.tt/1rZVYcQ via IFTTT
Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Patel TD, Vázquez A, Marchiano E, Sanghvi S, Eloy JA, Baredes S, Park RC Abstract OBJECTIVE/HYPOTHESIS: The aim of this population-based study is to analyze the survival benefits of elective neck dissection (END) over neck observation in T1/T2N0M0 oral tongue squamous cell carcinoma (OT-SCC) cases. STUDY DESIGN: Retrospective administrative database analysis. SUBJECTS AND METHODS: The SEER database (Surveillance, Epi... περισσότερα »
Endoscopic Resection of Sinonasal Malignancy: A Systematic Review and Meta-analysis.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Endoscopic Resection of Sinonasal Malignancy: A Systematic Review and Meta-analysis.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Rawal RB, Farzal Z, Federspiel JJ, Sreenath SB, Thorp BD, Zanation AM Abstract OBJECTIVES: The use of endoscopic approaches for sinonasal malignancy resection has increased, but survival data are limited secondary to disease rarity and new surgical technique. Here we present a systematic review and meta-analysis of endoscopic endonasal resection of sinonasal malignancy. DATA SOURCES: MEDLINE, PubMed Central, NCBI Bookshelf, Cochrane Library, cli... περισσότερα »
Predictors of Failed and Delayed Decannulation after Head and Neck Surgery.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Predictors of Failed and Delayed Decannulation after Head and Neck Surgery.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Isaac A, Zhang H, Varshney S, Hamilton S, Harris JR, O'Connell DA, Biron VL, Seikaly H Abstract OBJECTIVE: To determine the variables that are predictive of failed decannulation (FD), delayed decannulation (DD), and days to decannulation in patients who underwent head and neck cancer resection with free tissue transfer reconstruction for head and neck squamous cell carcinoma. DESIGN: Case series with chart review. SETTING: Tertiary care otolaryngology-hea...περισσότερα »
Functional Outcomes after Salvage Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Functional Outcomes after Salvage Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Fink DS, Sibley H, Kunduk M, Schexnaildre M, Sutton C, Kakade-Pawar A, McWhorter AJ Abstract OBJECTIVES: Transoral laser microsurgery (TLM) has been increasingly used in lieu of total laryngectomy to treat malignancy after definitive radiation. There are few data in the literature regarding functional outcomes. We retrospectively reviewed voice and swallowing outcomes in patients who underwent TLM for recurrent laryngeal carcino...περισσότερα »
Long-term Results of a Multicenter Randomized Phase III Trial of Induction Chemotherapy With Cisplatin, 5-fluorouracil, ± Docetaxel for Larynx Preservation.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Long-term Results of a Multicenter Randomized Phase III Trial of Induction Chemotherapy With Cisplatin, 5-fluorouracil, ± Docetaxel for Larynx Preservation.* J Natl Cancer Inst. 2016 Apr;108(4) Authors: Janoray G, Pointreau Y, Garaud P, Chapet S, Alfonsi M, Sire C, Jadaud E, Calais G Abstract BACKGROUND: The purpose of GORTEC 2000-01 was to compare the long-term efficacy and safety of induction chemotherapy with cisplatin (P) and 5-fluorouracil (F) with or without docetaxel (T) for larynx preservation. METHODS: O... περισσότερα »
Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Efficacy of Elective Neck Dissection in T1/T2N0M0 Oral Tongue Squamous Cell Carcinoma: A Population-Based Analysis.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Patel TD, Vázquez A, Marchiano E, Sanghvi S, Eloy JA, Baredes S, Park RC Abstract OBJECTIVE/HYPOTHESIS: The aim of this population-based study is to analyze the survival benefits of elective neck dissection (END) over neck observation in T1/T2N0M0 oral tongue squamous cell carcinoma (OT-SCC) cases. STUDY DESIGN: Retrospective administrative database analysis. SUBJECTS AND METHODS: The SEER database (Surveillance, Epi... περισσότερα »
Endoscopic Resection of Sinonasal Malignancy: A Systematic Review and Meta-analysis.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Endoscopic Resection of Sinonasal Malignancy: A Systematic Review and Meta-analysis.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Rawal RB, Farzal Z, Federspiel JJ, Sreenath SB, Thorp BD, Zanation AM Abstract OBJECTIVES: The use of endoscopic approaches for sinonasal malignancy resection has increased, but survival data are limited secondary to disease rarity and new surgical technique. Here we present a systematic review and meta-analysis of endoscopic endonasal resection of sinonasal malignancy. DATA SOURCES: MEDLINE, PubMed Central, NCBI Bookshelf, Cochrane Library, cli... περισσότερα »
Predictors of Failed and Delayed Decannulation after Head and Neck Surgery.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Predictors of Failed and Delayed Decannulation after Head and Neck Surgery.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Isaac A, Zhang H, Varshney S, Hamilton S, Harris JR, O'Connell DA, Biron VL, Seikaly H Abstract OBJECTIVE: To determine the variables that are predictive of failed decannulation (FD), delayed decannulation (DD), and days to decannulation in patients who underwent head and neck cancer resection with free tissue transfer reconstruction for head and neck squamous cell carcinoma. DESIGN: Case series with chart review. SETTING: Tertiary care otolaryngology-hea...περισσότερα »
Functional Outcomes after Salvage Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Functional Outcomes after Salvage Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Fink DS, Sibley H, Kunduk M, Schexnaildre M, Sutton C, Kakade-Pawar A, McWhorter AJ Abstract OBJECTIVES: Transoral laser microsurgery (TLM) has been increasingly used in lieu of total laryngectomy to treat malignancy after definitive radiation. There are few data in the literature regarding functional outcomes. We retrospectively reviewed voice and swallowing outcomes in patients who underwent TLM for recurrent laryngeal carcino...περισσότερα »
p53 and p16 in oral epithelial dysplasia and oral squamous cell carcinoma: A study of 208 cases.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*p53 and p16 in oral epithelial dysplasia and oral squamous cell carcinoma: A study of 208 cases.* Indian J Pathol Microbiol. 2016 Apr-Jun;59(2):153-8 Authors: Cuevas Gonzalez JC, Gaitan Cepeda LA, Borges Yanez SA, Cornejo AD, Mori Estevez AD, Huerta ER Abstract BACKGROUND: The use of p16 and p53 as biomarkers of malignant transformation of oral epithelial dysplasia (OED) and biological behavior of oral squamous cell carcinoma (OSCC) is controversial. AIM: To determine the immunoexpression of p16 and p53 in OED and OSCC and to establish their possible relation to histopathological... περισσότερα »
Myiasis with Musca domestica (housefly) larvae in a child with chronic otitis media
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Unusual pseudomyiasis with Musca domestica (housefly) larvae in a child with chronic otitis media: *Zafar Iqbal, Satish Chandra Sharma, Hiba Sami, Amit Kumar* Indian Journal of Otology 2016 22(2):132-134 Myiasis is a disease caused by fly larvae and aural myiasis is a rare clinic condition often occurring in children or mentally retarded people. We report the case of an unusual presentation of a unilateral aural myiasis in a 3-year-old female child patient belonging to a slum with unilateral chronic otitis media caused by Musca domestica (housefly) larvae. Eight larvae were rem... περισσότερα »
TP53 Mutations in Head and Neck Squamous Cell Carcinoma and Their Impact on Disease Progression and Treatment Response.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*TP53 Mutations in Head and Neck Squamous Cell Carcinoma and Their Impact on Disease Progression and Treatment Response.* J Cell Biochem. 2016 May 11; Authors: Zhou G, Liu Z, Myers JN Abstract Recent studies describing the mutational landscape of head and neck squamous cell carcinoma (HNSCC) on a genomic scale by our group and others, including The Cancer Genome Atlas, have provided unprecedented perspective for understanding the molecular pathogenesis of HNSCC progression and response to treatment. These studies confirmed that mutations of the TP53 tumor suppressor gene were the... περισσότερα »
Detection of molecular signatures of oral squamous cell carcinoma and normal epithelium - application of a novel methodology for unsupervised segmentation of imaging mass spectrometry data.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Detection of molecular signatures of oral squamous cell carcinoma and normal epithelium - application of a novel methodology for unsupervised segmentation of imaging mass spectrometry data.* Proteomics. 2016 Mar 1; Authors: Widlak P, Mrukwa G, Kalinowska M, Pietrowska M, Chekan M, Wierzgon J, Gawin M, Drazek G, Polanska J Abstract Intra-tumor heterogeneity is a vivid problem of molecular oncology that could be addressed by imaging mass spectrometry. Here we aimed to assess molecular heterogeneity of oral squamous cell carcinoma and to detect signatures discriminating normal and ... περισσότερα »
Treatment outcome of ion beam therapy in eight patients with head and neck cancers.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Treatment outcome of ion beam therapy in eight patients with head and neck cancers.* Eur Arch Otorhinolaryngol. 2016 May 11; Authors: Ohkubo JI, Hohchi N, Takeuchi S, Ikezaki S, Kise Y, Koizumi H, Suzuki H Abstract Ion beam therapy has enabled us to treat formerly untreatable malignant tumors. The aim of the present study was to investigate the long-term follow-up course of patients with head and neck cancers who received ion beam therapy. The subjects were 8 patients (3 men and 5 women aged 43-78 years) with head and neck cancers who visited our department from 2006 to 2015 an...περισσότερα »
Primary Malignant Melanoma of Pleura: A Case Report and Literature Review.
*Primary Malignant Melanoma of Pleura: A Case Report and Literature Review.* Diagn Cytopathol. 2016 May 11; Authors: Agarwal P, Nambiyar K, Manju Kaushal, Bhardwaj M Abstract Malignant melanoma is one of the most aggressive and treatment resistant skin cancers. India enjoys a low incidence of melanoma, and age specific incidence rates for cutaneous malignant melanoma (CMM) are being less than 0.5 per 1,000,000. This could be due to under-reporting of melanoma on account of a low index of suspicion by clinicians and pathologists alike. Most common site for origin of primary melanom...περισσότερα »
Malignant Perivascular Epithelioid Cell Neoplasm (PEComa) of the Pelvis: A Case Report.
*Malignant Perivascular Epithelioid Cell Neoplasm (PEComa) of the Pelvis: A Case Report.* Urol Case Rep. 2016 May;6:36-38 Authors: D'Andrea D, Hanspeter E, D'Elia C, Martini T, Pycha A Abstract Perivascular epithelioid cell neoplasms (PEComa) are rare mesenchymal tumors that can occur in any part of the body and have unpredictable pathological behavior. They are usually benign, but may be malignant. We present a case of malignant PEComa of the pelvic retroperitoneum treated with radical surgery. PMID: 27169023 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on I... περισσότερα »
Seminal Vesicle Leiomyoma Mimicking Extra-prostatic Extension of Prostatic Adenocarcinoma.
*Seminal Vesicle Leiomyoma Mimicking Extra-prostatic Extension of Prostatic Adenocarcinoma.* Urol Case Rep. 2016 May;6:18-20 Authors: Arnold SJ, Lin FC, Eldersveld JM, Phung MC, Walker JR, Nguyen TT Abstract Leiomyomas are common smooth muscle neoplasms; however, leiomyomas of the seminal vesicles are extremely rare. We report a case of seminal vesicle leiomyoma in a 55-year-old African American male who underwent robot assisted laparoscopic prostatectomy (RALP) for Gleason 8 (4 + 4) adenocarcinoma. An incidental nodule arising from the left seminal vesicle was discovered during ... περισσότερα »
Villous Tumor of the Urinary Bladder Resembling Low-grade Mucinous Neoplasm of the Appendix.
*Villous Tumor of the Urinary Bladder Resembling Low-grade Mucinous Neoplasm of the Appendix.* Urol Case Rep. 2016 May;6:4-6 Authors: Ito A, Sakura Y, Sugimoto M, Kakehi Y, Kuroda N Abstract Mucinous neoplasms of the urinary tract are very rare. We present a 63-year-old-women who had a sessile papillary villous tumor in urinary bladder. Although transurethral resection of the bladder tumor (TURBT) was performed, the villous tumor repetitively recurred and gradually spread to the entire surface of bladder lumen. Histopathologic and immunohistochemical examination showed that the l...περισσότερα »
Coexistence of resistance to thyroid hormone and papillary thyroid carcinoma.
*Coexistence of resistance to thyroid hormone and papillary thyroid carcinoma.* Endocrinol Diabetes Metab Case Rep. 2016;2016:160003 Authors: Igata M, Tsuruzoe K, Kawashima J, Kukidome D, Kondo T, Motoshima H, Shimoda S, Furukawa N, Nishikawa T, Miyamura N, Araki E Abstract Resistance to thyroid hormone (RTH) is a syndrome of reduced tissue responsiveness to thyroid hormones. RTH is majorly caused by mutations in the thyroid hormone receptor beta (THRB) gene. Recent studies indicated a close association of THRB mutations with human cancers, but the role of THRB mutation in carcin... περισσότερα »
Inflammatory Pseudotumor of the Spleen Masquerading as Splenic Malignancy.
*Inflammatory Pseudotumor of the Spleen Masquerading as Splenic Malignancy.* Oman Med J. 2016 Mar;31(2):154-157 Authors: Hassan M, Pujani M, Jairajpuri ZS, Rana S, Goel A, Jetley S Abstract Inflammatory pseudotumors (IPTs) of the spleen are extremely rare, benign tumors of unknown etiology, and are most frequently detected incidentally. We report a case of IPT of the spleen in a 19-year-old male, who presented to the Hamdard Institute of Medical Sciences and Research, New Delhi, with a history of pain and heaviness in the left hypochondrium. On clinical examination, splenomegaly w...περισσότερα »
Two Cases of Carcinosarcomas of the Ovary Involved in Hereditary Cancer Syndromes.
*Two Cases of Carcinosarcomas of the Ovary Involved in Hereditary Cancer Syndromes.* Int J Gynecol Pathol. 2016 May 10; Authors: Carnevali IW, Cimetti L, Sahnane N, Libera L, Cavallero A, Formenti G, Riva C, Tibiletti MG Abstract Ovarian carcinosarcomas (OCS), also known as malignant mixed mesodermal/Müllerian tumors, are rare neoplasms (1%-4% of all malignant ovarian tumors) composed of high-grade malignant epithelial and mesenchymal elements. OCS occurs in older women. It is associated with a poor outcome and is usually not involved in inherited cancer syndromes. We present 2 ...περισσότερα »
Predictors of survival in parotid adenocarcinoma not otherwise specified: a National Cancer Database study of 3155 patients.
*Predictors of survival in parotid adenocarcinoma not otherwise specified: a National Cancer Database study of 3155 patients.* Head Neck. 2016 May 10; Authors: Zhan KY, Huang AT, Khaja SF, Bell D, Day TA Abstract BACKGROUND: Parotid adenocarcinoma not otherwise specified (PANOS) is a common parotid cancer, but studies specifically on this subject are limited. METHODS: We conducted a retrospective review of the National Cancer Database. RESULTS: Ten percent of all parotid cancers were PANOS (n = 3155). Median age was 67 years. Most patients were men (62.8%) with high-grade histology... περισσότερα »
Primary retroperitoneal mucinous cystadenocarcinoma in a male patient.
*Primary retroperitoneal mucinous cystadenocarcinoma in a male patient.* Indian J Pathol Microbiol. 2016 Apr-Jun;59(2):229-231 Authors: Khurana A, Mukherjee U, Singaravel S Abstract Primary retroperitoneal mucinous neoplasms are extremely rare tumors. Less than sixty cases have been reported in international literature until date, with striking female predominance. We report a case of primary mucinous cystadenocarcinoma of the retroperitoneum in a 51-year-old male presenting with nonspecific abdominal complaints. This case is being highlighted for its rare occurrence in a male pat...περισσότερα »
Persistent Müllerian duct syndrome of mixed anatomical variant (combined male and female type) with mixed germ cell tumor of left intra-abdominal testis.
*Persistent Müllerian duct syndrome of mixed anatomical variant (combined male and female type) with mixed germ cell tumor of left intra-abdominal testis.* Indian J Pathol Microbiol. 2016 Apr-Jun;59(2):212-215 Authors: Mohapatra M, Subramanya YS Abstract Persistent Müllerian duct syndrome (PMDS) is a rare form of internal male pseudohermaphroditism characterized by retention of Müllerian duct derivatives in a phenotypically and karyotypically male patient. Deficiency of anti-Müllerian hormone (AMH) secretion or resistance to AMH action due to defective AMH-II receptor is presumed... περισσότερα »
A rare case of multicentric secretory carcinoma of breast in an adult female with review of literature.
*A rare case of multicentric secretory carcinoma of breast in an adult female with review of literature.* Indian J Pathol Microbiol. 2016 Apr-Jun;59(2):209-211 Authors: Kulkarni MM, Khandeparkar SG, Joshi AR, Dhande AN Abstract Secretory breast carcinomas (SBCs) are considered one of the rarest types of BCs accounting for <0.15% of all breast cancers. The lesions are typically solitary, but rare multicentric cases have been reported. SBC have characteristic histopathological, immunohistochemical, and electron microscopic findings. Children and adolescents with SBC have a favorable...περισσότερα »
Primary mature cystic teratoma with carcinoid mimicking an adrenal tumor: Report of a rare association and review of literature.
*Primary mature cystic teratoma with carcinoid mimicking an adrenal tumor: Report of a rare association and review of literature.* Indian J Pathol Microbiol. 2016 Apr-Jun;59(2):200-202 Authors: Narla SL, Jacob S, Kurian A, Parameswaran A Abstract Teratomas are neoplasms comprising of tissues derived from more than one germ layer. Most common sites are gonads, sacrococcygeal, mediastinal, retroperitoneal, and pineal region. Here, we report a case of 2 -year-old previously healthy female toddlerwho presented with fever and right upper quadrant abdominal pain. Magnetic resonance imag...περισσότερα »
Detection and monitoring of the BRAF mutation in circulating tumor cells and circulating tumor DNA in BRAF-mutated lung adenocarcinoma.
*Detection and monitoring of the BRAF mutation in circulating tumor cells and circulating tumor DNA in BRAF-mutated lung adenocarcinoma.* J Thorac Oncol. 2016 May 7; Authors: Guibert N, Pradines A, Casanova A, Farella M, Keller L, Soria JC, Favre G, Mazieres J Abstract INTRODUCTION: Non-invasive methods, such as liquid biopsies, are needed to avoid iterative biopsies in this era of personalized therapy. BRAF is a rare oncogenic driver that is mutated in 2% of non-small-cell lung cancers (NSCLC) and responds to BRAF inhibitors. CASE REPORTS: Six patients, treated for metastatic BRA...περισσότερα »
Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin.
*Novel patient-derived xenograft mouse model for pancreatic acinar cell carcinoma demonstrates single agent activity of oxaliplatin.* J Transl Med. 2016;14(1):129 Authors: Hall JC, Marlow LA, Mathias AC, Dawson LK, Durham WF, Meshaw KA, Mullin RJ, Synnott AJ, Small DL, Krishna M, von Hoff D, Schüler J, Hart SN, Couch FJ, Colon-Otero G, Copland JA Abstract BACKGROUND: Pancreatic acinar cell carcinoma (PACC) is a rare malignancy, accounting for <1 % of all pancreatic neoplasms. Very few retrospective studies are available to help guide management. We previously reported the case of...περισσότερα »
The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer.
*The Fanconi anemia DNA damage repair pathway in the spotlight for germline predisposition to colorectal cancer.* Eur J Hum Genet. 2016 May 11; Authors: Esteban-Jurado C, Franch-Expósito S, Muñoz J, Ocaña T, Carballal S, López-Cerón M, Cuatrecasas M, Vila-Casadesús M, Lozano JJ, Serra E, Beltran S, Brea-Fernández A, Ruiz-Ponte C, Castells A, Bujanda L, Garre P, Caldés T, Cubiella J, Balaguer F, Castellví-Bel S Abstract Colorectal cancer (CRC) is one of the most common neoplasms in the world. Fanconi anemia (FA) is a very rare genetic disease causing bone marrow failure, congenita...περισσότερα »
Primary Hepatic Small Cell Carcinoma: Two Case Reports, Molecular Characterization and Pooled Analysis of Known Clinical Data.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Primary Hepatic Small Cell Carcinoma: Two Case Reports, Molecular Characterization and Pooled Analysis of Known Clinical Data.* Anticancer Res. 2016 Jan;36(1):271-7 Authors: Shastri A, Msaouel P, Montagna C, White S, Delio M, Patel K, Alexis K, Strakhan M, Elrafei TN, Reed LJ Abstract Primary hepatic small cell carcinoma (HSCC) is a rare malignancy that has previously been described in only few case reports. The clinicopathological course, natural history, molecular markers and ideal treatment strategy for this t... περισσότερα »
The contribution of rare variation to prostate cancer heritability.
[image: http:--http://ift.tt/1pviIAx] Related Articles *The contribution of rare variation to prostate cancer heritability.* Nat Genet. 2016 Jan;48(1):30-5 Authors: Mancuso N, Rohland N, Rand KA, Tandon A, Allen A, Quinque D, Mallick S, Li H, Stram A, Sheng X, Kote-Jarai Z, Easton DF, Eeles RA, PRACTICAL consortium, Le Marchand L, Lubwama A, Stram D, Watya S, Conti DV, Henderson B, Haiman CA, Pasaniuc B, Reich D Abstract We report targeted sequencing of 63 known prostate cancer risk regions in a multi-ancestry study of 9,237 men and use the data to explore the contribution of low... περισσότερα »
Coexistence of resistance to thyroid hormone and papillary thyroid carcinoma.
*Coexistence of resistance to thyroid hormone and papillary thyroid carcinoma.* Endocrinol Diabetes Metab Case Rep. 2016;2016:160003 Authors: Igata M, Tsuruzoe K, Kawashima J, Kukidome D, Kondo T, Motoshima H, Shimoda S, Furukawa N, Nishikawa T, Miyamura N, Araki E Abstract Resistance to thyroid hormone (RTH) is a syndrome of reduced tissue responsiveness to thyroid hormones. RTH is majorly caused by mutations in the thyroid hormone receptor beta (THRB) gene. Recent studies indicated a close association of THRB mutations with human cancers, but the role of THRB mutation in carcin... περισσότερα »
Reference values for insulin-like growth factor I (IGF-I) serum concentrations: comparison of six immunoassays.
*Reference values for insulin-like growth factor I (IGF-I) serum concentrations: comparison of six immunoassays.* J Clin Endocrinol Metab. 2016 May 11;:jc20161257 Authors: Chanson P, Arnoux A, Mavromati M, Brailly-Tabard S, Massart C, Young J, Piketty ML, Souberbielle JC, VARIETE Investigators Abstract CONTEXT: Measurement of IGF-I is essential for diagnosis and management of patientswith disorders affecting the somatotropic axis. However, even when IGF-I kit manufacturers follow recent consensus guidelines, different kits can give very different results for a given sample. OBJECT...περισσότερα »
Clinical, genetic and biochemical characteristics of early-onset diabetes in the Finnish population.
*Clinical, genetic and biochemical characteristics of early-onset diabetes in the Finnish population.* J Clin Endocrinol Metab. 2016 May 11;:jc20154296 Authors: Hanna H, Päivi M, Jorma I, Päivi N, Riitta V, Päivi K, Kirsti NS, Jagadish V, Joose R, Alena S, Jonna M, Teemu K, Mikael K, Timo O, Markku L Abstract CONTEXT: Major advances have been made in the classification and genetics of monogenic diabetes in infancy. OBJECTIVE: To characterize different forms of diabetes diagnosed during the first year of life. DESIGN: Patients diagnosed with diabetes before the age of one year in te...περισσότερα »
Anterior loop of the mental nerve, mental foramen and incisive nerve emergency: tridimensional assessment and surgical applications.
*Anterior loop of the mental nerve, mental foramen and incisive nerve emergency: tridimensional assessment and surgical applications.* Surg Radiol Anat. 2016 May 11; Authors: Prados-Frutos JC, Salinas-Goodier C, Manchón Á, Rojo R Abstract PURPOSE: The aim of this study was to investigate the prevalence and length of the anterior loop (AL), the distance from this landmark to the alveolar crest and its relation with the shape of the foramen and emergency pattern in the Spanish population on helical computed tomography scan (helical CT scan) through tridimensional reconstructions. ME...περισσότερα »
upper respiratory tract infection
45 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2016/05/12 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1TH3bVB via IFTTT
Complex influence of gonadotropins and sex steroid hormones on QT interval duration.
*Complex influence of gonadotropins and sex steroid hormones on QT interval duration.* J Clin Endocrinol Metab. 2016 May 11;:jc20161877 Authors: Abehsira G, Bachelot A, Badilini F, Koehl L, Lebot M, Favet C, Touraine P, Funck-Brentano C, Salem JE Abstract CONTEXT: QT interval duration is longer in women than in men. Sex steroid hormones have inconsistently been suggested to explain this difference. Implication of gonadotropins has never been studied. OBJECTIVE: We here report the combined influence of sex steroid hormones and gonadotropins on QT interval duration in healthy subjec... περισσότερα »
Reference values for insulin-like growth factor I (IGF-I) serum concentrations: comparison of six immunoassays.
*Reference values for insulin-like growth factor I (IGF-I) serum concentrations: comparison of six immunoassays.* J Clin Endocrinol Metab. 2016 May 11;:jc20161257 Authors: Chanson P, Arnoux A, Mavromati M, Brailly-Tabard S, Massart C, Young J, Piketty ML, Souberbielle JC, VARIETE Investigators Abstract CONTEXT: Measurement of IGF-I is essential for diagnosis and management of patientswith disorders affecting the somatotropic axis. However, even when IGF-I kit manufacturers follow recent consensus guidelines, different kits can give very different results for a given sample. OBJECT...περισσότερα »
Clinical, genetic and biochemical characteristics of early-onset diabetes in the Finnish population.
*Clinical, genetic and biochemical characteristics of early-onset diabetes in the Finnish population.* J Clin Endocrinol Metab. 2016 May 11;:jc20154296 Authors: Hanna H, Päivi M, Jorma I, Päivi N, Riitta V, Päivi K, Kirsti NS, Jagadish V, Joose R, Alena S, Jonna M, Teemu K, Mikael K, Timo O, Markku L Abstract CONTEXT: Major advances have been made in the classification and genetics of monogenic diabetes in infancy. OBJECTIVE: To characterize different forms of diabetes diagnosed during the first year of life. DESIGN: Patients diagnosed with diabetes before the age of one year in te...περισσότερα »
upper respiratory tract infection; +45 new citations
45 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2016/05/12 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1TH3bVB via IFTTT
Impaired auditory selective attention ameliorated by cognitive training with graded exposure to noise in patients with traumatic brain injury.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Impaired auditory selective attention ameliorated by cognitive training with graded exposure to noise in patients with traumatic brain injury.* Neuropsychologia. 2015 Aug;75:74-87 Authors: Dundon NM, Dockree SP, Buckley V, Merriman N, Carton M, Clarke S, Roche RA, Lalor EC, Robertson IH, Dockree PM Abstract Patients who suffer traumatic brain injury frequently report difficulty concentrating on tasks and completing routine activities in noisy and distracting environments. Such impairments can have long-term negati... περισσότερα »
Ongoing outbreak of invasive listeriosis due to serotype 1/2a Listeria monocytogenes, Ancona province, Italy, January 2015 to February 2016.
*Ongoing outbreak of invasive listeriosis due to serotype 1/2a Listeria monocytogenes, Ancona province, Italy, January 2015 to February 2016.* Euro Surveill. 2016 Apr 28;21(17) Authors: Marini E, Magi G, Vincenzi C, Manso E, Facinelli B Abstract In the first seven weeks of 2016, five serotype 1/2a Listeria monocytogenes isolates were collected from patients with invasive listeriosis in Ancona province in Italy. These strains and six 1/2a isolates identified in 2015 in the same area were typed by ERIC-PCR and PFGE. A clonal relationship, documented between the two sets of isolates,... περισσότερα »
Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: results of an outbreak investigation in Germany, April 2015 to February 2016.
*Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: results of an outbreak investigation in Germany, April 2015 to February 2016.* Euro Surveill. 2016 Apr 28;21(17) Authors: Haller S, Höller C, Jacobshagen A, Hamouda O, Abu Sin M, Monnet DL, Plachouras D, Eckmanns T Abstract Invasive infections with Mycobacterium chimaera were reported in patients with previous open chest surgery and exposure to contaminated heater-cooler units (HCUs). We present results of the surveillance of clinical cases and ...περισσότερα »
Silent dissemination of colistin-resistant Escherichia coli in South America could contribute to the global spread of the mcr-1 gene.
*Silent dissemination of colistin-resistant Escherichia coli in South America could contribute to the global spread of the mcr-1 gene.* Euro Surveill. 2016 Apr 28;21(17) Authors: Fernandes MR, Moura Q, Sartori L, Silva KC, Cunha MP, Esposito F, Lopes R, Otutumi LK, Gonçalves DD, Dropa M, Matté MH, Monte DF, Landgraf M, Francisco GR, Bueno MF, de Oliveira Garcia D, Knöbl T, Moreno AM, Lincopan N Abstract During a Brazilian multicentric antimicrobial resistance surveillance study, colistin resistance was investigated in 4,620 Enterobacteriaceae isolated from human, animal, food and ...περισσότερα »
Persisting transmission of carbapenemase-producing Klebsiella pneumoniae due to an environmental reservoir in a university hospital, France, 2012 to 2014.
*Persisting transmission of carbapenemase-producing Klebsiella pneumoniae due to an environmental reservoir in a university hospital, France, 2012 to 2014.* Euro Surveill. 2016 Apr 28;21(17) Authors: Clarivet B, Grau D, Jumas-Bilak E, Jean-Pierre H, Pantel A, Parer S, Lotthé A Abstract In France, the proportion of episodes of carbapenemase-producing Enterobacteriaceae (CPE) with no recent stay or hospitalisation abroad is increasing. In this study, we investigate epidemiological links between apparently unrelated cases of OXA-48-producing Klebsiella pneumoniae (Kp OXA-48) coloni...περισσότερα »
Best practices in ranking communicable disease threats: a literature review, 2015.
*Best practices in ranking communicable disease threats: a literature review, 2015.* Euro Surveill. 2016 Apr 28;21(17) Authors: O'Brien EC, Taft R, Geary K, Ciotti M, Suk JE Abstract The threat of serious, cross-border communicable disease outbreaks in Europe poses a significant challenge to public health and emergency preparedness because the relative likelihood of these threats and the pathogens involved are constantly shifting in response to a range of changing disease drivers. To inform strategic planning by enabling effective resource allocation to manage the consequences of... περισσότερα »
Marked increase in leptospirosis infections in humans and dogs in the Netherlands, 2014.
*Marked increase in leptospirosis infections in humans and dogs in the Netherlands, 2014.* Euro Surveill. 2016 Apr 28;21(17) Authors: Pijnacker R, Goris MG, Te Wierik MJ, Broens EM, van der Giessen JW, de Rosa M, Wagenaar JA, Hartskeerl RA, Notermans DW, Maassen K, Schimmer B Abstract In the Netherlands, 97 human leptospirosis cases were notified in 2014. This represents a 4.6-fold increase in autochthonous cases (n = 60) compared with the annual average between 2010 and 2013. Most cases had symptom onset between June and November. This marked increase in humans coincided with a... περισσότερα »
The 2014 Military Health System Research Symposium Awards: Recognizing Those Pushing the Science Envelope.
*The 2014 Military Health System Research Symposium Awards: Recognizing Those Pushing the Science Envelope.* Mil Med. 2016 May;181(5S):265-270 Authors: Reilly PA PMID: 27168583 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1sghKKh via IFTTT
Screening of Nanoemulsion Formulations and Identification of NB-201 as an Effective Topical Antimicrobial for Staphylococcus aureus in a Mouse Model of Infected Wounds.
*Screening of Nanoemulsion Formulations and Identification of NB-201 as an Effective Topical Antimicrobial for Staphylococcus aureus in a Mouse Model of Infected Wounds.* Mil Med. 2016 May;181(5S):259-264 Authors: Fan Y, Ciotti S, Cao Z, Eisma R, Baker J, Wang SH Abstract Despite advances in antimicrobial therapies, wound infection remains a global public health concern. We aimed to formulate and assess various nanoemulsions (NEs) for potential effectiveness as stable antimicrobial agents suitable for topic application. A total of 106 NEs were developed that varied with respect t...περισσότερα »
Intra-Arterial Perimortem Resuscitation Using a Micellar Colloid.
*Intra-Arterial Perimortem Resuscitation Using a Micellar Colloid.* Mil Med. 2016 May;181(5S):253-258 Authors: Simpkins C, Talluri K, Williams M Abstract OBJECTIVE: The following were studied in a perimortem mouse model of rapid blood loss: (a) efficacy of a prototypical micellar colloid, Intralipid 20%, (IL20), compared to albumin (b) comparison of intra-arterial and intravenous resuscitation, (c) efficacy of IL20 at a volume 2 × the volume of blood removed, and (d) efficacy of oxygenated IL20 after clinical death (CD). METHODS: CD, the absence of breathing and zero blood pressur... περισσότερα »
Exploratory Laparotomy for Proximal Vascular Control in Combat-Related Injuries.
*Exploratory Laparotomy for Proximal Vascular Control in Combat-Related Injuries.* Mil Med. 2016 May;181(5S):247-252 Authors: Hathaway E, Glaser J, Cardarelli C, Dunne J, Elster E, Safford S, Rodriguez C Abstract BACKGROUND: Combat casualties have endured an increase in traumatic lower extremity amputations secondary to improvised explosive devices. Often surgical control of the proximal vasculature is required. We evaluate the safety profile of exploratory laparotomy (EXLAP) for proximal control (PC) in combat-injured patients. METHODS: Records of 845 combat casualties from June...περισσότερα »
Evaluation of a Bovine Vascular Graft in Sheep.
*Evaluation of a Bovine Vascular Graft in Sheep.* Mil Med. 2016 May;181(5S):240-246 Authors: Knapp J, Rizzo A, Maxwell M, Duran C, Cheung D Abstract The study objective was to determine safety and efficacy of a treated bovine vascular xenograft, in two Good Laboratory Practice compliant studies in sheep following carotid graft implantation. In one study, a 3- to 5-mm diameter xenograft was implanted into the right carotid artery of male sheep and compared to autologous jugular vein and a polymeric grafts similarly implanted. In a second study, a 9.5- to 14-mm diameter xenograft s... περισσότερα »
Magnetic Nanoparticles as a Potential Vehicle for Corneal Endothelium Repair.
*Magnetic Nanoparticles as a Potential Vehicle for Corneal Endothelium Repair.* Mil Med. 2016 May;181(5S):232-239 Authors: Cornell LE, Wehmeyer JL, Johnson AJ, Desilva MN, Zamora DO Abstract The corneal endothelium is paramount to the health and function of the cornea as damage to this cell layer can lead to corneal edema, opacification, and ultimately vision loss. Transplantation of the corneal endothelium is associated with numerous limitations, including graft rejection, thus an alternative therapeutic treatment is needed to restore endothelial layer integrity. We hypothesize ... περισσότερα »
Development of Lyophilized Loop-Mediated Isothermal Amplification Reagents for the Detection of Leptospira.
*Development of Lyophilized Loop-Mediated Isothermal Amplification Reagents for the Detection of Leptospira.* Mil Med. 2016 May;181(5S):227-231 Authors: Chen HW, Weissenberger G, Ching WM Abstract Leptospirosis is considered to be the most widespread zoonosis. This worldwide emerging infectious disease is caused by the pathogenic species belonging to the genus Leptospira. Polymerase chain reaction (PCR)-based diagnostic assays have been developed for detecting Leptospira DNA in cell cultures and clinical samples. Because PCR requires specialized equipment and extensive end-user t... περισσότερα »
A rare mutation in a rare tumor--SMARCB1-deficient malignant glomus tumor.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *A rare mutation in a rare tumor--SMARCB1-deficient malignant glomus tumor.* Genes Chromosomes Cancer. 2016 Jan;55(1):107-9 Authors: Dabek B, Kram A, Kubrak J, Kurzawski M, Wojcik P, Machnicki MM, Stoklosa T, Rydzanicz M, Ploski R, Debiec-Rychter M PMID: 26391213 [PubMed - indexed for MEDLINE] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/27g63TA via IFTTT
Endobronchial Watanabe Spigot Placement for a Secondary Pneumothorax.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Endobronchial Watanabe Spigot Placement for a Secondary Pneumothorax.* J Bronchology Interv Pulmonol. 2015 Jul;22(3):278-80 Authors: Ueda Y, Huang CL, Itotani R, Fukui M Abstract Although bevacizumab has several adverse effects, pneumothorax is rare. This is the first case of initial treatment using an Endobronchial Watanabe Spigot (EWS) for pneumothorax after bevacizumab-containing chemotherapy. A 56-year-old woman with recurrent breast cancer was treated with bevacizumab. Pneumothorax occurred 6 days after the l... περισσότερα »
Subcutaneous infection caused by Blastoschizomyces capitatus post allogeneic hematopoietic transplant and its successful treatment with voriconazole.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Subcutaneous infection caused by Blastoschizomyces capitatus post allogeneic hematopoietic transplant and its successful treatment with voriconazole.* Transpl Infect Dis. 2015 Aug;17(4):588-92 Authors: Devadas SK, Bhat V, Khattry N Abstract We describe a 33-year-old man with relapsed acute myelogenous leukemia who developed subcutaneous nodules >6 months after allogeneic hematopoietic stem cell transplant. These nodules were caused by Blastoschizomyces capitatus. The lesions progressed after treatment with a posa... περισσότερα »
Metastases of head and neck squamous cell carcinoma to soft tissue of fingertips.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 33 δευτερόλεπτα
*Metastases of head and neck squamous cell carcinoma to soft tissue of fingertips.* Indian J Med Paediatr Oncol. 2016 Apr-Jun;37(2):122 Authors: Shetty N, Sameer MS, Fernandes H, Shet D PMID: 27168713 [PubMed - as supplied by publisher] from squamous cell carcinoma via ok on Inoreader http://ift.tt/1XmG2xC via IFTTT
Systemic Depletion of Macrophages in the Subacute Phase of Wound Healing Reduces Hypertrophic Scar Formation
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
ABSTRACT Hypertrophic scars are caused by trauma or burn injuries to the deep dermis and can cause cosmetic disfigurement and psychological issues. Studies suggest that M2-like macrophages are pro-fibrotic and contribute to hypertrophic scar formation. A previous study from our lab showed that M2 macrophages were present in developing hypertrophic scar tissues in vivo at […]
Venous Ulcers: So Many Guidelines, Too Many Guidelines?
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
from Aesthetic via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZIkom7 via IFTTT
Milk: a postnatal imprinting system stabilizing FoxP3 expression and regulatory T cell differentiation
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
Breastfeeding has protective effects for the development of allergies and atopy. Recent evidence underlines that consumption of unboiled farm milk in early life is a key factor preventing the development of at… from Allergy via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZI00BN via IFTTT
[A rare cause of dyspnea on exertion].
[image: http:--http://ift.tt/1WrDJue] Related Articles *[A rare cause of dyspnea on exertion].* G Ital Cardiol (Rome). 2016 Jan;17(1):58-61 Authors: Maccari U, Rosini CF, Scala R, Magnolfi AL, Felici M, Bolognese L Abstract Vascular rings are rare anomalies accounting for 1% to 3% of all congenital heart diseases with a similar frequency in both sexes, which can result in a variable degree of extrinsic compression of the trachea and esophagus. We report the case of a 46-year-old woman with symptomatic dyspnea and double aortic arch that caused esophageal tracheal compression. Cons... περισσότερα »
Functional Outcomes after Salvage Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.
*Functional Outcomes after Salvage Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Fink DS, Sibley H, Kunduk M, Schexnaildre M, Sutton C, Kakade-Pawar A, McWhorter AJ Abstract OBJECTIVES: Transoral laser microsurgery (TLM) has been increasingly used in lieu of total laryngectomy to treat malignancy after definitive radiation. There are few data in the literature regarding functional outcomes. We retrospectively reviewed voice and swallowing outcomes in patients who underwent TLM for recurrent laryngeal carcino...περισσότερα »
[A rare cause of dyspnea on exertion].
[image: http:--http://ift.tt/1WrDJue] Related Articles *[A rare cause of dyspnea on exertion].* G Ital Cardiol (Rome). 2016 Jan;17(1):58-61 Authors: Maccari U, Rosini CF, Scala R, Magnolfi AL, Felici M, Bolognese L Abstract Vascular rings are rare anomalies accounting for 1% to 3% of all congenital heart diseases with a similar frequency in both sexes, which can result in a variable degree of extrinsic compression of the trachea and esophagus. We report the case of a 46-year-old woman with symptomatic dyspnea and double aortic arch that caused esophageal tracheal compression. Consi... περισσότερα »
Metal sulfide photocatalyst composed of ubiquitous elements for solar hydrogen production
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC03199D, Communication Yuhiro Shiga, Naoto Umezawa, Nagarajan Srinivasan, Satoshi Koyasu, Etsuo Sakai, Masahiro Miyauchi A visible-light-sensitive tin sulfide photocatalyst was designed based on a ubiquitous elemental strategy and density functional theory (DFT) calculations. Computational analysis suggested that tin monosulfide (SnS) would be more efficient... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1UVb6UO via IFTTT
Spin-crossover complex encapsulation within a magnetic metal-organic framework
[image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC03667H, Communication Alexandre Abherve, Thais Maria Grancha, Jesus Ferrando-Soria, Miguel Clemente Leon, Eugenio Coronado, Francesc Lloret, Emilio Pardo, Joao C. Waerenborgh The solid-state incorporation of a mononuclear iron(III) complex within the pores of a magnetic 3D metal-organic framework (MOF) in a single crystal to single crystal process, leads to the formation... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1T... περισσότερα »
A Label-free Fluorescent Adenosine Triphosphate Biosensor via Overhanging Aptamer-Triggered Enzyme Protection and Target Recycling Amplification
[image: CrossMark.jpg] *Analyst*, 2016, Accepted Manuscript *DOI*: 10.1039/C6AN00816J, Communication Zhihui Dai, Zhaoyin Wang, Jian Zhao Herein, a label-free fluorescent adenosine triphosphate (ATP) aptasensor is fabricated with DNA hairpin and overhanging aptamer. In the presence of ATP, overhanging sequences of aptamer may form prefered substrates of... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1sgiGOK via IFTTT
A Multidimensional Scaling Study of Native and Non-Native Listeners' Perception of Second Language Speech.
*A Multidimensional Scaling Study of Native and Non-Native Listeners' Perception of Second Language Speech.* Percept Mot Skills. 2016 Apr;122(2):470-89 Authors: Foote JA, Trofimovich P Abstract Second language speech learning is predicated on learners' ability to notice differences between their own language output and that of their interlocutors. Because many learners interact primarily with other second language users, it is crucial to understand which dimensions underlie the perception of second language speech by learners, compared to native speakers. For this study, 15 non-n...περισσότερα »
Increased motor preparation activity during fluent single word production in DS: A correlate for stuttering frequency and severity.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Increased motor preparation activity during fluent single word production in DS: A correlate for stuttering frequency and severity.* Neuropsychologia. 2015 Aug;75:1-10 Authors: Vanhoutte S, Santens P, Cosyns M, van Mierlo P, Batens K, Corthals P, De Letter M, Van Borsel J Abstract Abnormal speech motor preparation is suggested to be a neural characteristic of stuttering. One of the neurophysiological substrates of motor preparation is the contingent negative variation (CNV). The CNV is an event-related, slow nega... περισσότερα »
When meaning is useless.
Related Articles *When meaning is useless.* Memory. 2015;23(7):1001-12 Authors: Benetello A, Cecchetto C, Papagno C Abstract The aim of this study is to disentangle the relative contribution of semantic and phonological representation in immediate serial recall. Indeed, short-term memory (STM) performance could be enhanced by familiarity with the phonological form of the word only or together with semantic information. Participants learned two sets of words in an unknown language: for one set they acquired both phonology and semantics, while for the other only phonology. After t...περισσότερα »
Correlation between the severity of critically ill patients and clinical predictors of bronchial aspiration.
*Correlation between the severity of critically ill patients and clinical predictors of bronchial aspiration.* J Bras Pneumol. 2016 Apr;42(2):114-120 Authors: Medeiros GC, Sassi FC, Zambom LS, Andrade CR Abstract OBJECTIVE: To determine whether the severity of non-neurological critically ill patients correlates with clinical predictors of bronchial aspiration. METHODS: We evaluated adults undergoing prolonged orotracheal intubation (> 48 h) and bedside swallowing assessment within the first 48 h after extubation. We collected data regarding the risk of bronchial aspiration perform...περισσότερα »
A Multidimensional Scaling Study of Native and Non-Native Listeners' Perception of Second Language Speech.
*A Multidimensional Scaling Study of Native and Non-Native Listeners' Perception of Second Language Speech.* Percept Mot Skills. 2016 Apr;122(2):470-89 Authors: Foote JA, Trofimovich P Abstract Second language speech learning is predicated on learners' ability to notice differences between their own language output and that of their interlocutors. Because many learners interact primarily with other second language users, it is crucial to understand which dimensions underlie the perception of second language speech by learners, compared to native speakers. For this study, 15 non-n...περισσότερα »
Increased motor preparation activity during fluent single word production in DS: A correlate for stuttering frequency and severity.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Increased motor preparation activity during fluent single word production in DS: A correlate for stuttering frequency and severity.* Neuropsychologia. 2015 Aug;75:1-10 Authors: Vanhoutte S, Santens P, Cosyns M, van Mierlo P, Batens K, Corthals P, De Letter M, Van Borsel J Abstract Abnormal speech motor preparation is suggested to be a neural characteristic of stuttering. One of the neurophysiological substrates of motor preparation is the contingent negative variation (CNV). The CNV is an event-related, slow negat... περισσότερα »
When meaning is useless.
Related Articles *When meaning is useless.* Memory. 2015;23(7):1001-12 Authors: Benetello A, Cecchetto C, Papagno C Abstract The aim of this study is to disentangle the relative contribution of semantic and phonological representation in immediate serial recall. Indeed, short-term memory (STM) performance could be enhanced by familiarity with the phonological form of the word only or together with semantic information. Participants learned two sets of words in an unknown language: for one set they acquired both phonology and semantics, while for the other only phonology. After th...περισσότερα »
Exploratory Laparotomy for Proximal Vascular Control in Combat-Related Injuries.
*Exploratory Laparotomy for Proximal Vascular Control in Combat-Related Injuries.* Mil Med. 2016 May;181(5S):247-252 Authors: Hathaway E, Glaser J, Cardarelli C, Dunne J, Elster E, Safford S, Rodriguez C Abstract BACKGROUND: Combat casualties have endured an increase in traumatic lower extremity amputations secondary to improvised explosive devices. Often surgical control of the proximal vasculature is required. We evaluate the safety profile of exploratory laparotomy (EXLAP) for proximal control (PC) in combat-injured patients. METHODS: Records of 845 combat casualties from June...περισσότερα »
Evaluation of a Bovine Vascular Graft in Sheep.
*Evaluation of a Bovine Vascular Graft in Sheep.* Mil Med. 2016 May;181(5S):240-246 Authors: Knapp J, Rizzo A, Maxwell M, Duran C, Cheung D Abstract The study objective was to determine safety and efficacy of a treated bovine vascular xenograft, in two Good Laboratory Practice compliant studies in sheep following carotid graft implantation. In one study, a 3- to 5-mm diameter xenograft was implanted into the right carotid artery of male sheep and compared to autologous jugular vein and a polymeric grafts similarly implanted. In a second study, a 9.5- to 14-mm diameter xenograft s... περισσότερα »
Ongoing outbreak of invasive listeriosis due to serotype 1/2a Listeria monocytogenes, Ancona province, Italy, January 2015 to February 2016.
*Ongoing outbreak of invasive listeriosis due to serotype 1/2a Listeria monocytogenes, Ancona province, Italy, January 2015 to February 2016.* Euro Surveill. 2016 Apr 28;21(17) Authors: Marini E, Magi G, Vincenzi C, Manso E, Facinelli B Abstract In the first seven weeks of 2016, five serotype 1/2a Listeria monocytogenes isolates were collected from patients with invasive listeriosis in Ancona province in Italy. These strains and six 1/2a isolates identified in 2015 in the same area were typed by ERIC-PCR and PFGE. A clonal relationship, documented between the two sets of isolates,... περισσότερα »
Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: results of an outbreak investigation in Germany, April 2015 to February 2016.
*Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: results of an outbreak investigation in Germany, April 2015 to February 2016.* Euro Surveill. 2016 Apr 28;21(17) Authors: Haller S, Höller C, Jacobshagen A, Hamouda O, Abu Sin M, Monnet DL, Plachouras D, Eckmanns T Abstract Invasive infections with Mycobacterium chimaera were reported in patients with previous open chest surgery and exposure to contaminated heater-cooler units (HCUs). We present results of the surveillance of clinical cases and ...περισσότερα »
Silent dissemination of colistin-resistant Escherichia coli in South America could contribute to the global spread of the mcr-1 gene.
*Silent dissemination of colistin-resistant Escherichia coli in South America could contribute to the global spread of the mcr-1 gene.* Euro Surveill. 2016 Apr 28;21(17) Authors: Fernandes MR, Moura Q, Sartori L, Silva KC, Cunha MP, Esposito F, Lopes R, Otutumi LK, Gonçalves DD, Dropa M, Matté MH, Monte DF, Landgraf M, Francisco GR, Bueno MF, de Oliveira Garcia D, Knöbl T, Moreno AM, Lincopan N Abstract During a Brazilian multicentric antimicrobial resistance surveillance study, colistin resistance was investigated in 4,620 Enterobacteriaceae isolated from human, animal, food and ...περισσότερα »
Persisting transmission of carbapenemase-producing Klebsiella pneumoniae due to an environmental reservoir in a university hospital, France, 2012 to 2014.
*Persisting transmission of carbapenemase-producing Klebsiella pneumoniae due to an environmental reservoir in a university hospital, France, 2012 to 2014.* Euro Surveill. 2016 Apr 28;21(17) Authors: Clarivet B, Grau D, Jumas-Bilak E, Jean-Pierre H, Pantel A, Parer S, Lotthé A Abstract In France, the proportion of episodes of carbapenemase-producing Enterobacteriaceae (CPE) with no recent stay or hospitalisation abroad is increasing. In this study, we investigate epidemiological links between apparently unrelated cases of OXA-48-producing Klebsiella pneumoniae (Kp OXA-48) coloni...περισσότερα »
Best practices in ranking communicable disease threats: a literature review, 2015.
*Best practices in ranking communicable disease threats: a literature review, 2015.* Euro Surveill. 2016 Apr 28;21(17) Authors: O'Brien EC, Taft R, Geary K, Ciotti M, Suk JE Abstract The threat of serious, cross-border communicable disease outbreaks in Europe poses a significant challenge to public health and emergency preparedness because the relative likelihood of these threats and the pathogens involved are constantly shifting in response to a range of changing disease drivers. To inform strategic planning by enabling effective resource allocation to manage the consequences of... περισσότερα »
Marked increase in leptospirosis infections in humans and dogs in the Netherlands, 2014.
*Marked increase in leptospirosis infections in humans and dogs in the Netherlands, 2014.* Euro Surveill. 2016 Apr 28;21(17) Authors: Pijnacker R, Goris MG, Te Wierik MJ, Broens EM, van der Giessen JW, de Rosa M, Wagenaar JA, Hartskeerl RA, Notermans DW, Maassen K, Schimmer B Abstract In the Netherlands, 97 human leptospirosis cases were notified in 2014. This represents a 4.6-fold increase in autochthonous cases (n = 60) compared with the annual average between 2010 and 2013. Most cases had symptom onset between June and November. This marked increase in humans coincided with a... περισσότερα »
The 2014 Military Health System Research Symposium Awards: Recognizing Those Pushing the Science Envelope.
*The 2014 Military Health System Research Symposium Awards: Recognizing Those Pushing the Science Envelope.* Mil Med. 2016 May;181(5S):265-270 Authors: Reilly PA PMID: 27168583 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1sghKKh via IFTTT
Screening of Nanoemulsion Formulations and Identification of NB-201 as an Effective Topical Antimicrobial for Staphylococcus aureus in a Mouse Model of Infected Wounds.
*Screening of Nanoemulsion Formulations and Identification of NB-201 as an Effective Topical Antimicrobial for Staphylococcus aureus in a Mouse Model of Infected Wounds.* Mil Med. 2016 May;181(5S):259-264 Authors: Fan Y, Ciotti S, Cao Z, Eisma R, Baker J, Wang SH Abstract Despite advances in antimicrobial therapies, wound infection remains a global public health concern. We aimed to formulate and assess various nanoemulsions (NEs) for potential effectiveness as stable antimicrobial agents suitable for topic application. A total of 106 NEs were developed that varied with respect t...περισσότερα »
Intra-Arterial Perimortem Resuscitation Using a Micellar Colloid.
*Intra-Arterial Perimortem Resuscitation Using a Micellar Colloid.* Mil Med. 2016 May;181(5S):253-258 Authors: Simpkins C, Talluri K, Williams M Abstract OBJECTIVE: The following were studied in a perimortem mouse model of rapid blood loss: (a) efficacy of a prototypical micellar colloid, Intralipid 20%, (IL20), compared to albumin (b) comparison of intra-arterial and intravenous resuscitation, (c) efficacy of IL20 at a volume 2 × the volume of blood removed, and (d) efficacy of oxygenated IL20 after clinical death (CD). METHODS: CD, the absence of breathing and zero blood pressur... περισσότερα »
Exploratory Laparotomy for Proximal Vascular Control in Combat-Related Injuries.
*Exploratory Laparotomy for Proximal Vascular Control in Combat-Related Injuries.* Mil Med. 2016 May;181(5S):247-252 Authors: Hathaway E, Glaser J, Cardarelli C, Dunne J, Elster E, Safford S, Rodriguez C Abstract BACKGROUND: Combat casualties have endured an increase in traumatic lower extremity amputations secondary to improvised explosive devices. Often surgical control of the proximal vasculature is required. We evaluate the safety profile of exploratory laparotomy (EXLAP) for proximal control (PC) in combat-injured patients. METHODS: Records of 845 combat casualties from June...περισσότερα »
Evaluation of a Bovine Vascular Graft in Sheep.
*Evaluation of a Bovine Vascular Graft in Sheep.* Mil Med. 2016 May;181(5S):240-246 Authors: Knapp J, Rizzo A, Maxwell M, Duran C, Cheung D Abstract The study objective was to determine safety and efficacy of a treated bovine vascular xenograft, in two Good Laboratory Practice compliant studies in sheep following carotid graft implantation. In one study, a 3- to 5-mm diameter xenograft was implanted into the right carotid artery of male sheep and compared to autologous jugular vein and a polymeric grafts similarly implanted. In a second study, a 9.5- to 14-mm diameter xenograft s... περισσότερα »
Magnetic Nanoparticles as a Potential Vehicle for Corneal Endothelium Repair.
*Magnetic Nanoparticles as a Potential Vehicle for Corneal Endothelium Repair.* Mil Med. 2016 May;181(5S):232-239 Authors: Cornell LE, Wehmeyer JL, Johnson AJ, Desilva MN, Zamora DO Abstract The corneal endothelium is paramount to the health and function of the cornea as damage to this cell layer can lead to corneal edema, opacification, and ultimately vision loss. Transplantation of the corneal endothelium is associated with numerous limitations, including graft rejection, thus an alternative therapeutic treatment is needed to restore endothelial layer integrity. We hypothesize ... περισσότερα »
Development of Lyophilized Loop-Mediated Isothermal Amplification Reagents for the Detection of Leptospira.
*Development of Lyophilized Loop-Mediated Isothermal Amplification Reagents for the Detection of Leptospira.* Mil Med. 2016 May;181(5S):227-231 Authors: Chen HW, Weissenberger G, Ching WM Abstract Leptospirosis is considered to be the most widespread zoonosis. This worldwide emerging infectious disease is caused by the pathogenic species belonging to the genus Leptospira. Polymerase chain reaction (PCR)-based diagnostic assays have been developed for detecting Leptospira DNA in cell cultures and clinical samples. Because PCR requires specialized equipment and extensive end-user t... περισσότερα »
Face Transplantation in a Highly Sensitized Recipient.
*Face Transplantation in a Highly Sensitized Recipient.* Mil Med. 2016 May;181(5S):221-226 Authors: Chandraker A, Arscott R, Murphy G, Lian C, Bueno E, Marty F, Rennke H, Milford E, Tullius S, Pomahac B Abstract Face transplantation was performed in a highly sensitized recipient with positive preoperative crossmatch and subsequent antibody-mediated rejection. The recipient was a 45-year-old female with extensive conventional reconstructions after chemical burns over the majority of the body. Residual quality of life and facial functions were poor. Levels of circulating anti-human... περισσότερα »
Adaptive Virtual Reality Training to Optimize Military Medical Skills Acquisition and Retention.
*Adaptive Virtual Reality Training to Optimize Military Medical Skills Acquisition and Retention.* Mil Med. 2016 May;181(5S):214-220 Authors: Siu KC, Best BJ, Kim JW, Oleynikov D, Ritter FE Abstract The Department of Defense has pursued the integration of virtual reality simulation into medical training and applications to fulfill the need to train 100,000 military health care personnel annually. Medical personnel transitions, both when entering an operational area and returning to the civilian theater, are characterized by the need to rapidly reacquire skills that are essential ... περισσότερα »
Developing a Cognitive and Communications Tool for Burn Intensive Care Unit Clinicians.
*Developing a Cognitive and Communications Tool for Burn Intensive Care Unit Clinicians.* Mil Med. 2016 May;181(5S):205-213 Authors: Nemeth C, Anders S, Strouse R, Grome A, Crandall B, Pamplin J, Salinas J, Mann-Salinas E Abstract BACKGROUND: Burn Intensive Care Unit (BICU) work is necessarily complex and depends on clinician actions, resources, and variable patient responses to interventions. Clinicians use large volumes of data that are condensed in time, but separated across resources, to care for patients. Correctly designed health information technology (IT) systems may help...περισσότερα »
Evaluation of Miniature Wireless Vital Signs Monitor in a Trauma Intensive Care Unit.
*Evaluation of Miniature Wireless Vital Signs Monitor in a Trauma Intensive Care Unit.* Mil Med. 2016 May;181(5S):199-204 Authors: Meizoso JP, Allen CJ, Ray JJ, Van Haren RM, Teisch LF, Baez XR, Livingstone AS, Namias N, Schulman CI, Proctor KG Abstract A previous study demonstrated basic proof of principle of the value of a miniature wireless vital signs monitor (MWVSM, MiniMedic, Athena GTX, Des Moines, Iowa) for battlefield triage However, there were unanswered questions related to sensor reliability and uncontrolled conditions in the prehospital environment. This study determ...περισσότερα »
Telehealth Coaching: Impact on Dietary and Physical Activity Contributions to Bone Health During a Military Deployment.
*Telehealth Coaching: Impact on Dietary and Physical Activity Contributions to Bone Health During a Military Deployment.* Mil Med. 2016 May;181(5S):191-198 Authors: Frank LL, McCarthy MS Abstract PURPOSE: To examine the difference in bone health and body composition via blood biomarkers, bone mineral density, anthropometrics and dietary intake following deployment to Afghanistan among soldiers randomized to receive telehealth coaching promoting nutrition and exercise. METHODS: This was a prospective, longitudinal, cluster-randomized, controlled trial with repeated measures in 234 περισσότερα »
An Overview of the Efficacy of a Next Generation Electroceutical Wound Care Device.
*An Overview of the Efficacy of a Next Generation Electroceutical Wound Care Device.* Mil Med. 2016 May;181(5S):184-190 Authors: Kim H, Park S, Housler G, Marcel V, Cross S, Izadjoo M Abstract Novel approaches including nonpharmacological methodologies for prevention and control of microbial pathogens and emerging antibiotic resistance are urgently needed. Procellera is a wound care device consisting of a matrix of alternating silver (Ag) and zinc (Zn) dots held in position on a polyester substrate with a biocompatible binder. This electroceutical medical device is capable of gen... περισσότερα »
System Design Verification for Closed Loop Control of Oxygenation With Concentrator Integration.
*System Design Verification for Closed Loop Control of Oxygenation With Concentrator Integration.* Mil Med. 2016 May;181(5S):177-183 Authors: Gangidine MM, Blakeman TC, Branson RD, Johannigman JA Abstract BACKGROUND: Addition of an oxygen concentrator into a control loop furthers previous work in autonomous control of oxygenation. Software integrates concentrator and ventilator function from a single control point, ensuring maximum efficiency by placing a pulse of oxygen at the beginning of the breath. We sought to verify this system. METHODS: In a test lung, fraction of inspired ...περισσότερα »
Signal Enhancement in Ligand-Receptor Interactions using Dynamic Polymers at Quartz Crystal Microbalance Sensors
[image: CrossMark.jpg] *Analyst*, 2016, Accepted Manuscript *DOI*: 10.1039/C6AN00735J, Communication Gunnar Duner, Henrik Anderson, Bjorn Ingemarsson, Zhichao Pei, Teodor Astrup, Olof Ramstrom The signal enhancement properties of QCM sensors based on dynamic, biotinylated poly(acrylic acid) brushes has been studied in interaction studies with an anti-biotin Fab fragment. The poly(acrylic acid) sensors showed... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1qfxBqx via IFTTT
Face Transplantation in a Highly Sensitized Recipient.
*Face Transplantation in a Highly Sensitized Recipient.* Mil Med. 2016 May;181(5S):221-226 Authors: Chandraker A, Arscott R, Murphy G, Lian C, Bueno E, Marty F, Rennke H, Milford E, Tullius S, Pomahac B Abstract Face transplantation was performed in a highly sensitized recipient with positive preoperative crossmatch and subsequent antibody-mediated rejection. The recipient was a 45-year-old female with extensive conventional reconstructions after chemical burns over the majority of the body. Residual quality of life and facial functions were poor. Levels of circulating anti-human... περισσότερα »
Adaptive Virtual Reality Training to Optimize Military Medical Skills Acquisition and Retention.
*Adaptive Virtual Reality Training to Optimize Military Medical Skills Acquisition and Retention.* Mil Med. 2016 May;181(5S):214-220 Authors: Siu KC, Best BJ, Kim JW, Oleynikov D, Ritter FE Abstract The Department of Defense has pursued the integration of virtual reality simulation into medical training and applications to fulfill the need to train 100,000 military health care personnel annually. Medical personnel transitions, both when entering an operational area and returning to the civilian theater, are characterized by the need to rapidly reacquire skills that are essential ... περισσότερα »
Effect of Vocal Fold Medialization on Dysphagia in Patients with Unilateral Vocal Fold Immobility.
*Effect of Vocal Fold Medialization on Dysphagia in Patients with Unilateral Vocal Fold Immobility.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Cates DJ, Venkatesan NN, Strong B, Kuhn MA, Belafsky PC Abstract OBJECTIVE: The effect of vocal fold medialization (VFM) on vocal improvement in persons with unilateral vocal fold immobility (UVFI) is well established. The effect of VFM on the symptom of dysphagia is uncertain. The purpose of this study is to evaluate dysphagia symptoms in patients with UVFI pre- and post-VFM. STUDY DESIGN: Case series with chart review. SETTING: Ac... περισσότερα »
Delayed Esophagus Perforation after Anterior Cervical Spine Surgery.
*Delayed Esophagus Perforation after Anterior Cervical Spine Surgery.* Korean J Neurotrauma. 2015 Oct;11(2):191-194 Authors: Yang SY, Lee SB, Cho KS Abstract Esophageal perforation is a serious possible complication after anterior cervical discectomy and fusion (ACDF). It usually occurs during the first postoperative day. Esophageal perforation is a potentially life-threatening complication. A 63-year-old man who underwent ACDF 8 years prior visited our emergency room with recurrent aspiration pneumonia, fever, dysphagia and neck pain. Endoscopic study showed esophageal perforatio...περισσότερα »
Dysphagia Management and Research in an Acute-Care Military Treatment Facility: The Role of Applied Informatics.
*Dysphagia Management and Research in an Acute-Care Military Treatment Facility: The Role of Applied Informatics.* Mil Med. 2016 May;181(5S):138-144 Authors: Solomon NP, Dietsch AM, Dietrich-Burns KE, Styrmisdottir EL, Armao CS Abstract PURPOSE: This report describes the development and preliminary analysis of a database for traumatically injured military service members with dysphagia. METHODS: A multidimensional database was developed to capture clinical variables related to swallowing. Data were derived from clinical records and instrumental swallow studies, and ranged from de... περισσότερα »
Fork test: A new simple and reliable consistency measurement for the dysphagia diet.
*Fork test: A new simple and reliable consistency measurement for the dysphagia diet.* Geriatr Nurs. 2016 May 7; Authors: Park JW, Kim IJ, Lee HJ Abstract The objective of this study was to validate fork test which is a simple tool to assess the consistency of food. The consistencies of 27 water and thickener mixtures were measured with a viscometer. These measures were then compared to those obtained with fork test to evaluate the validity of fork test. The inter-observer and intra-observer reliabilities of the fork test were assessed with an intra-class correlation coefficient.... περισσότερα »
Oropharyngeal Dysphagia in Dermatomyositis: Associations with Clinical and Laboratory Features Including Autoantibodies.
*Oropharyngeal Dysphagia in Dermatomyositis: Associations with Clinical and Laboratory Features Including Autoantibodies.* PLoS One. 2016;11(5):e0154746 Authors: Mugii N, Hasegawa M, Matsushita T, Hamaguchi Y, Oohata S, Okita H, Yahata T, Someya F, Inoue K, Murono S, Fujimoto M, Takehara K Abstract OBJECTIVE: Dysphagia develops with low frequency in patients with dermatomyositis. Our objective was to determine the clinical and laboratory features that can estimate the development of dysphagia in dermatomyositis. METHODS: This study included 92 Japanese patients with adult-onset de... περισσότερα »
Diagnosis and evaluation of 100 dysphagia patients using videoendoscopy at a core hospital of a local city in Japan.
*Diagnosis and evaluation of 100 dysphagia patients using videoendoscopy at a core hospital of a local city in Japan.* Odontology. 2016 May 11; Authors: Yonenaga K, Majima HJ, Oyama S, Ishibashi K, Tanno H Abstract Japan has entered an era of a super-aging population, and given the importance of oral nutrition, the need to evaluate swallowing function has increased. Herein, we contribute to continued developments in evaluating eating and swallowing functions by describing current videoendoscopy (VE) usage and trends to evaluate and diagnose causes of dysphagia. In all, 100 patien...περισσότερα »
Test-Retest Reliability of Detection Time Data Measured Using a Masseter Electromyogram in Healthy Young Adults: Preliminary Analysis of Data.
*Test-Retest Reliability of Detection Time Data Measured Using a Masseter Electromyogram in Healthy Young Adults: Preliminary Analysis of Data.* Percept Mot Skills. 2016 Apr;122(2):509-17 Authors: Miyaoka S, Miyaoka Y Abstract Few studies have assessed test-retest reliability of flavor detection time in semisolid and solid foods. In this study, test-retest reliability was assessed in 16 healthy young adults (22.6 ± 5.5 years old) on the data collected using a masseter electromyography-based system between two experimental sessions approximately 35 days apart. The overall correlati...περισσότερα »
Pharyngeal Electrical Stimulation for Treatment of Dysphagia in Subacute Stroke: A Randomized Controlled Trial.
*Pharyngeal Electrical Stimulation for Treatment of Dysphagia in Subacute Stroke: A Randomized Controlled Trial.* Stroke. 2016 May 10; Authors: Bath PM, Scutt P, Love J, Clavé P, Cohen D, Dziewas R, Iversen HK, Ledl C, Ragab S, Soda H, Warusevitane A, Woisard V, Hamdy S, Swallowing Treatment Using Pharyngeal Electrical Stimulation (STEPS) Trial Investigators Abstract BACKGROUND AND PURPOSE: Dysphagia is common after stroke, associated with increased death and dependency, and treatment options are limited. Pharyngeal electric stimulation (PES) is a novel treatment for poststroke ... περισσότερα »
Functional Outcomes after Salvage Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.
*Functional Outcomes after Salvage Transoral Laser Microsurgery for Laryngeal Squamous Cell Carcinoma.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Fink DS, Sibley H, Kunduk M, Schexnaildre M, Sutton C, Kakade-Pawar A, McWhorter AJ Abstract OBJECTIVES: Transoral laser microsurgery (TLM) has been increasingly used in lieu of total laryngectomy to treat malignancy after definitive radiation. There are few data in the literature regarding functional outcomes. We retrospectively reviewed voice and swallowing outcomes in patients who underwent TLM for recurrent laryngeal carcino...περισσότερα »
Effect of Vocal Fold Medialization on Dysphagia in Patients with Unilateral Vocal Fold Immobility.
*Effect of Vocal Fold Medialization on Dysphagia in Patients with Unilateral Vocal Fold Immobility.* Otolaryngol Head Neck Surg. 2016 May 10; Authors: Cates DJ, Venkatesan NN, Strong B, Kuhn MA, Belafsky PC Abstract OBJECTIVE: The effect of vocal fold medialization (VFM) on vocal improvement in persons with unilateral vocal fold immobility (UVFI) is well established. The effect of VFM on the symptom of dysphagia is uncertain. The purpose of this study is to evaluate dysphagia symptoms in patients with UVFI pre- and post-VFM. STUDY DESIGN: Case series with chart review. SETTING: Ac... περισσότερα »
[A rare cause of dyspnea on exertion].
[image: http:--http://ift.tt/1WrDJue] Related Articles *[A rare cause of dyspnea on exertion].* G Ital Cardiol (Rome). 2016 Jan;17(1):58-61 Authors: Maccari U, Rosini CF, Scala R, Magnolfi AL, Felici M, Bolognese L Abstract Vascular rings are rare anomalies accounting for 1% to 3% of all congenital heart diseases with a similar frequency in both sexes, which can result in a variable degree of extrinsic compression of the trachea and esophagus. We report the case of a 46-year-old woman with symptomatic dyspnea and double aortic arch that caused esophageal tracheal compression. Consi... περισσότερα »
Quantitative assessment of preoperative serum thyrotropin level and thyroid cancer.
*Quantitative assessment of preoperative serum thyrotropin level and thyroid cancer.* Oncotarget. 2016 May 6; Authors: Zheng J, Li C, Lu W, Wang C, Ai Z Abstract Thyroid stimulating hormone (TSH) is the major growth factor for thyrocytes, but the pathogenic role of serum TSH in thyroid cancer (TC) is unknown. The association between TSH level and the development of thyroid cancer has been widely evaluated recently. However, the results remain conflicting. To develop an understanding of the relationship between TSH exposure and thyroid cancer, a meta-analysis of 56 studies involvi...περισσότερα »
Ongoing outbreak of invasive listeriosis due to serotype 1/2a Listeria monocytogenes, Ancona province, Italy, January 2015 to February 2016.
*Ongoing outbreak of invasive listeriosis due to serotype 1/2a Listeria monocytogenes, Ancona province, Italy, January 2015 to February 2016.* Euro Surveill. 2016 Apr 28;21(17) Authors: Marini E, Magi G, Vincenzi C, Manso E, Facinelli B Abstract In the first seven weeks of 2016, five serotype 1/2a Listeria monocytogenes isolates were collected from patients with invasive listeriosis in Ancona province in Italy. These strains and six 1/2a isolates identified in 2015 in the same area were typed by ERIC-PCR and PFGE. A clonal relationship, documented between the two sets of isolates,... περισσότερα »
Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: results of an outbreak investigation in Germany, April 2015 to February 2016.
*Contamination during production of heater-cooler units by Mycobacterium chimaera potential cause for invasive cardiovascular infections: results of an outbreak investigation in Germany, April 2015 to February 2016.* Euro Surveill. 2016 Apr 28;21(17) Authors: Haller S, Höller C, Jacobshagen A, Hamouda O, Abu Sin M, Monnet DL, Plachouras D, Eckmanns T Abstract Invasive infections with Mycobacterium chimaera were reported in patients with previous open chest surgery and exposure to contaminated heater-cooler units (HCUs). We present results of the surveillance of clinical cases and ...περισσότερα »
Silent dissemination of colistin-resistant Escherichia coli in South America could contribute to the global spread of the mcr-1 gene.
*Silent dissemination of colistin-resistant Escherichia coli in South America could contribute to the global spread of the mcr-1 gene.* Euro Surveill. 2016 Apr 28;21(17) Authors: Fernandes MR, Moura Q, Sartori L, Silva KC, Cunha MP, Esposito F, Lopes R, Otutumi LK, Gonçalves DD, Dropa M, Matté MH, Monte DF, Landgraf M, Francisco GR, Bueno MF, de Oliveira Garcia D, Knöbl T, Moreno AM, Lincopan N Abstract During a Brazilian multicentric antimicrobial resistance surveillance study, colistin resistance was investigated in 4,620 Enterobacteriaceae isolated from human, animal, food and ...περισσότερα »
Persisting transmission of carbapenemase-producing Klebsiella pneumoniae due to an environmental reservoir in a university hospital, France, 2012 to 2014.
*Persisting transmission of carbapenemase-producing Klebsiella pneumoniae due to an environmental reservoir in a university hospital, France, 2012 to 2014.* Euro Surveill. 2016 Apr 28;21(17) Authors: Clarivet B, Grau D, Jumas-Bilak E, Jean-Pierre H, Pantel A, Parer S, Lotthé A Abstract In France, the proportion of episodes of carbapenemase-producing Enterobacteriaceae (CPE) with no recent stay or hospitalisation abroad is increasing. In this study, we investigate epidemiological links between apparently unrelated cases of OXA-48-producing Klebsiella pneumoniae (Kp OXA-48) coloni...περισσότερα »
Best practices in ranking communicable disease threats: a literature review, 2015.
*Best practices in ranking communicable disease threats: a literature review, 2015.* Euro Surveill. 2016 Apr 28;21(17) Authors: O'Brien EC, Taft R, Geary K, Ciotti M, Suk JE Abstract The threat of serious, cross-border communicable disease outbreaks in Europe poses a significant challenge to public health and emergency preparedness because the relative likelihood of these threats and the pathogens involved are constantly shifting in response to a range of changing disease drivers. To inform strategic planning by enabling effective resource allocation to manage the consequences of... περισσότερα »
Marked increase in leptospirosis infections in humans and dogs in the Netherlands, 2014.
*Marked increase in leptospirosis infections in humans and dogs in the Netherlands, 2014.* Euro Surveill. 2016 Apr 28;21(17) Authors: Pijnacker R, Goris MG, Te Wierik MJ, Broens EM, van der Giessen JW, de Rosa M, Wagenaar JA, Hartskeerl RA, Notermans DW, Maassen K, Schimmer B Abstract In the Netherlands, 97 human leptospirosis cases were notified in 2014. This represents a 4.6-fold increase in autochthonous cases (n = 60) compared with the annual average between 2010 and 2013. Most cases had symptom onset between June and November. This marked increase in humans coincided with a... περισσότερα »
The 2014 Military Health System Research Symposium Awards: Recognizing Those Pushing the Science Envelope.
*The 2014 Military Health System Research Symposium Awards: Recognizing Those Pushing the Science Envelope.* Mil Med. 2016 May;181(5S):265-270 Authors: Reilly PA PMID: 27168583 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1sghKKh
Screening of Nanoemulsion Formulations and Identification of NB-201 as an Effective Topical Antimicrobial for Staphylococcus aureus in a Mouse Model of Infected Wounds.
*Screening of Nanoemulsion Formulations and Identification of NB-201 as an Effective Topical Antimicrobial for Staphylococcus aureus in a Mouse Model of Infected Wounds.* Mil Med. 2016 May;181(5S):259-264 Authors: Fan Y, Ciotti S, Cao Z, Eisma R, Baker J, Wang SH Abstract Despite advances in antimicrobial therapies, wound infection remains a global public health concern. We aimed to formulate and assess various nanoemulsions (NEs) for potential effectiveness as stable antimicrobial agents suitable for topic application. A total of 106 NEs were developed that varied with respect t...περισσότερα »
Intra-Arterial Perimortem Resuscitation Using a Micellar Colloid.
*Intra-Arterial Perimortem Resuscitation Using a Micellar Colloid.* Mil Med. 2016 May;181(5S):253-258 Authors: Simpkins C, Talluri K, Williams M Abstract OBJECTIVE: The following were studied in a perimortem mouse model of rapid blood loss: (a) efficacy of a prototypical micellar colloid, Intralipid 20%, (IL20), compared to albumin (b) comparison of intra-arterial and intravenous resuscitation, (c) efficacy of IL20 at a volume 2 × the volume of blood removed, and (d) efficacy of oxygenated IL20 after clinical death (CD). METHODS: CD, the absence of breathing and zero blood pressur... περισσότερα »
Exploratory Laparotomy for Proximal Vascular Control in Combat-Related Injuries.
*Exploratory Laparotomy for Proximal Vascular Control in Combat-Related Injuries.* Mil Med. 2016 May;181(5S):247-252 Authors: Hathaway E, Glaser J, Cardarelli C, Dunne J, Elster E, Safford S, Rodriguez C Abstract BACKGROUND: Combat casualties have endured an increase in traumatic lower extremity amputations secondary to improvised explosive devices. Often surgical control of the proximal vasculature is required. We evaluate the safety profile of exploratory laparotomy (EXLAP) for proximal control (PC) in combat-injured patients. METHODS: Records of 845 combat casualties from June...περισσότερα »
Evaluation of a Bovine Vascular Graft in Sheep.
*Evaluation of a Bovine Vascular Graft in Sheep.* Mil Med. 2016 May;181(5S):240-246 Authors: Knapp J, Rizzo A, Maxwell M, Duran C, Cheung D Abstract The study objective was to determine safety and efficacy of a treated bovine vascular xenograft, in two Good Laboratory Practice compliant studies in sheep following carotid graft implantation. In one study, a 3- to 5-mm diameter xenograft was implanted into the right carotid artery of male sheep and compared to autologous jugular vein and a polymeric grafts similarly implanted. In a second study, a 9.5- to 14-mm diameter xenograft s... περισσότερα »
Magnetic Nanoparticles as a Potential Vehicle for Corneal Endothelium Repair.
*Magnetic Nanoparticles as a Potential Vehicle for Corneal Endothelium Repair.* Mil Med. 2016 May;181(5S):232-239 Authors: Cornell LE, Wehmeyer JL, Johnson AJ, Desilva MN, Zamora DO Abstract The corneal endothelium is paramount to the health and function of the cornea as damage to this cell layer can lead to corneal edema, opacification, and ultimately vision loss. Transplantation of the corneal endothelium is associated with numerous limitations, including graft rejection, thus an alternative therapeutic treatment is needed to restore endothelial layer integrity. We hypothesize ... περισσότερα »
Development of Lyophilized Loop-Mediated Isothermal Amplification Reagents for the Detection of Leptospira.
*Development of Lyophilized Loop-Mediated Isothermal Amplification Reagents for the Detection of Leptospira.* Mil Med. 2016 May;181(5S):227-231 Authors: Chen HW, Weissenberger G, Ching WM Abstract Leptospirosis is considered to be the most widespread zoonosis. This worldwide emerging infectious disease is caused by the pathogenic species belonging to the genus Leptospira. Polymerase chain reaction (PCR)-based diagnostic assays have been developed for detecting Leptospira DNA in cell cultures and clinical samples. Because PCR requires specialized equipment and extensive end-user t... περισσότερα »
Face Transplantation in a Highly Sensitized Recipient.
*Face Transplantation in a Highly Sensitized Recipient.* Mil Med. 2016 May;181(5S):221-226 Authors: Chandraker A, Arscott R, Murphy G, Lian C, Bueno E, Marty F, Rennke H, Milford E, Tullius S, Pomahac B Abstract Face transplantation was performed in a highly sensitized recipient with positive preoperative crossmatch and subsequent antibody-mediated rejection. The recipient was a 45-year-old female with extensive conventional reconstructions after chemical burns over the majority of the body. Residual quality of life and facial functions were poor. Levels of circulating anti-human... περισσότερα »
Adaptive Virtual Reality Training to Optimize Military Medical Skills Acquisition and Retention.
*Adaptive Virtual Reality Training to Optimize Military Medical Skills Acquisition and Retention.* Mil Med. 2016 May;181(5S):214-220 Authors: Siu KC, Best BJ, Kim JW, Oleynikov D, Ritter FE Abstract The Department of Defense has pursued the integration of virtual reality simulation into medical training and applications to fulfill the need to train 100,000 military health care personnel annually. Medical personnel transitions, both when entering an operational area and returning to the civilian theater, are characterized by the need to rapidly reacquire skills that are essential ... περισσότερα »
Developing a Cognitive and Communications Tool for Burn Intensive Care Unit Clinicians.
*Developing a Cognitive and Communications Tool for Burn Intensive Care Unit Clinicians.* Mil Med. 2016 May;181(5S):205-213 Authors: Nemeth C, Anders S, Strouse R, Grome A, Crandall B, Pamplin J, Salinas J, Mann-Salinas E Abstract BACKGROUND: Burn Intensive Care Unit (BICU) work is necessarily complex and depends on clinician actions, resources, and variable patient responses to interventions. Clinicians use large volumes of data that are condensed in time, but separated across resources, to care for patients. Correctly designed health information technology (IT) systems may help...περισσότερα »
Evaluation of Miniature Wireless Vital Signs Monitor in a Trauma Intensive Care Unit.
*Evaluation of Miniature Wireless Vital Signs Monitor in a Trauma Intensive Care Unit.* Mil Med. 2016 May;181(5S):199-204 Authors: Meizoso JP, Allen CJ, Ray JJ, Van Haren RM, Teisch LF, Baez XR, Livingstone AS, Namias N, Schulman CI, Proctor KG Abstract A previous study demonstrated basic proof of principle of the value of a miniature wireless vital signs monitor (MWVSM, MiniMedic, Athena GTX, Des Moines, Iowa) for battlefield triage However, there were unanswered questions related to sensor reliability and uncontrolled conditions in the prehospital environment. This study determ...περισσότερα »
Telehealth Coaching: Impact on Dietary and Physical Activity Contributions to Bone Health During a Military Deployment.
*Telehealth Coaching: Impact on Dietary and Physical Activity Contributions to Bone Health During a Military Deployment.* Mil Med. 2016 May;181(5S):191-198 Authors: Frank LL, McCarthy MS Abstract PURPOSE: To examine the difference in bone health and body composition via blood biomarkers, bone mineral density, anthropometrics and dietary intake following deployment to Afghanistan among soldiers randomized to receive telehealth coaching promoting nutrition and exercise. METHODS: This was a prospective, longitudinal, cluster-randomized, controlled trial with repeated measures in 234 ...περισσότερα »
An Overview of the Efficacy of a Next Generation Electroceutical Wound Care Device.
*An Overview of the Efficacy of a Next Generation Electroceutical Wound Care Device.* Mil Med. 2016 May;181(5S):184-190 Authors: Kim H, Park S, Housler G, Marcel V, Cross S, Izadjoo M Abstract Novel approaches including nonpharmacological methodologies for prevention and control of microbial pathogens and emerging antibiotic resistance are urgently needed. Procellera is a wound care device consisting of a matrix of alternating silver (Ag) and zinc (Zn) dots held in position on a polyester substrate with a biocompatible binder. This electroceutical medical device is capable of gen... περισσότερα »
System Design Verification for Closed Loop Control of Oxygenation With Concentrator Integration.
*System Design Verification for Closed Loop Control of Oxygenation With Concentrator Integration.* Mil Med. 2016 May;181(5S):177-183 Authors: Gangidine MM, Blakeman TC, Branson RD, Johannigman JA Abstract BACKGROUND: Addition of an oxygen concentrator into a control loop furthers previous work in autonomous control of oxygenation. Software integrates concentrator and ventilator function from a single control point, ensuring maximum efficiency by placing a pulse of oxygen at the beginning of the breath. We sought to verify this system. METHODS: In a test lung, fraction of inspired ...περισσότερα »
Characteristics and outcomes of emergency patients with self-inflicted injuries: a report from ambulance records in Osaka City, Japan
Few studies have evaluated the actual situations of emergency patients with self-inflicted injuries treated by emergency-medical-service (EMS) personnel. from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1sg8mq6 via IFTTT
Evaluating the Impact of Antibiotic Exposures as Time-Dependent Variables on the Acquisition of Carbapenem-Resistant Acinetobacter baumannii.
[image: wk-health-logo.gif] Objectives: To determine the time-dependent effect of antibiotics on the initial acquisition of carbapenem-resistant Acinetobacter baumannii. Design: Retrospective cohort study. Setting: Forty-bed trauma ICU in Miami, FL. Patients: All consecutive patients admitted to the unit from January 2010 to November 2011. Interventions: None. Measurements and Main Results: Patients underwent surveillance cultures at admission to the unit and weekly thereafter. The primary outcome was the acquisition of carbapenem-resistant A. baumannii on surveillance cultures. Da... περισσότερα »
Serum Biomarkers Help Predict Attention Problems in Critically Ill Children With Traumatic Brain Injury.
Objective: To evaluate the association between acute serum biomarkers, and the changes in attention at 1 year following traumatic brain injury. Design and Setting: A prospective observational and laboratory study conducted in PICUs at five Canadian children's hospitals. Study Population and Measurements: Fifty-eight patients aged 5 to 17 years with traumatic brain injury were enrolled in the study. Nine brain-specific and inflammatory serum protein biomarkers were measured multiple times over the first week following injury. Attention was measured at "baseline" to represent pre-inju... περισσότερα »
Learning From Experience: Improving Early Tracheal Extubation Success After Congenital Cardiac Surgery.
Objectives: The many advantages of early tracheal extubation following congenital cardiac surgery in young infants and children are now widely recognized. Benefits include avoiding the morbidity associated with prolonged intubation and the consequences of sedation and positive pressure ventilation in the setting of altered cardiopulmonary physiology. Our practice of tracheal extubation of young infants in the operating room following cardiac surgery has evolved and new challenges in the arena of postoperative sedation and pain management have appeared. Design: Review our institution...περισσότερα »
Quality Improvement is Research
This issue of Academic Emergency Medicine includes a manuscript: “Sustainable Mechanism to Reduce ED Length of Stay: The Use of Emergency Department Holding (ED Transition) Orders to Reduce ED Length of Stay” that describes a project designed to reduce ED crowding by admitting patients without having the inpatient physicians actually see them first. This is not a new idea of course and is one that has not been without controversy. There are clearly advantages in direct admissions: it can benefit the admitted patient by providing a more comfortable place to be treated, it certainly...περισσότερα »
Quantitative assessment of preoperative serum thyrotropin level and thyroid cancer.
*Quantitative assessment of preoperative serum thyrotropin level and thyroid cancer.* Oncotarget. 2016 May 6; Authors: Zheng J, Li C, Lu W, Wang C, Ai Z Abstract Thyroid stimulating hormone (TSH) is the major growth factor for thyrocytes, but the pathogenic role of serum TSH in thyroid cancer (TC) is unknown. The association between TSH level and the development of thyroid cancer has been widely evaluated recently. However, the results remain conflicting. To develop an understanding of the relationship between TSH exposure and thyroid cancer, a meta-analysis of 56 studies involvi...περισσότερα »
Can the Serum Level of Myostatin be Considered as an Informative Factor for Cachexia Prevention in Patients with Medullary Thyroid Cancer?
*Can the Serum Level of Myostatin be Considered as an Informative Factor for Cachexia Prevention in Patients with Medullary Thyroid Cancer?* Asian Pac J Cancer Prev. 2016;17 Spec No.:119-23 Authors: Hedayati M, Nozhat Z, Hannani M Abstract Thyroid cancer, the most common endocrine neoplasia, consists of four main types of carcinomas: papillary, follicular, and anaplastic, all with thyroid follicular origin, and medullary thyroid cancer (MTC) related to para-follicular cells. Cronic diseases such as diverse cancers may be associated with cachexia, especially at advanced stage. Canc...περισσότερα »
Prevalence of Types of Cancers in the Elderly Covered by Insurance of the Islamic Republic of Iran Broadcasting Company in 2015 - Comparison with Younger Groups.
*Prevalence of Types of Cancers in the Elderly Covered by Insurance of the Islamic Republic of Iran Broadcasting Company in 2015 - Comparison with Younger Groups.* Asian Pac J Cancer Prev. 2016;17 Spec No.:269-73 Authors: Roshani Z, Akbari Kamrani AA, Shati M, Sahaf R Abstract Presently, the world population of the elderly is growing. By improving health hygiene and welfare indicators, mortality and birth rates decrease and life expectancy increases, making the present century the century of elderly. Aging is one of the main risk factors for development of cancer, which itself is... περισσότερα »
Trends in Incidence of Common Cancers in Iran.
*Trends in Incidence of Common Cancers in Iran.* Asian Pac J Cancer Prev. 2016;17 Spec No.:39-42 Authors: Enayatrad M, Mirzaei M, Salehiniya H, Karimirad MR, Vaziri S, Mansouri F, Moudi A Abstract Cancer is a major public health problem in Iran. The aim of this study was to evaluate trends in incidence of ten common cancers in Iran, based on the national cancer registry reports from 2004 to 2009. This epidemiological study was carried out based on existing age-standardized estimate cancer data from the national report on cancer registry/Ministry of Health in Iran. The obtained da... περισσότερα »
Atypical teratoid/rhabdoid tumors–current concepts, advances in biology, and potential future therapies
Atypical teratoid/rhabdoid tumor (AT/RT) is the most common malignant CNS tumor of children below 6 months of age. The majority of AT/RTs demonstrate genomic alterations in SMARCB1 (INI1, SNF5, BAF47) or, to a lesser extent, SMARCA4 (BRG1) of the SWItch/sucrose nonfermentable chromatin remodeling complex. Recent transcription and methylation profiling studies suggest the existence of molecular… Continue reading Atypical teratoid/rhabdoid tumors–current concepts, advances in biology, and potential future therapies
Endocrine outcomes with proton and photon radiotherapy for standard risk medulloblastoma
Background Endocrine dysfunction is a common sequela of craniospinal irradiation (CSI). Dosimetric data suggest that proton radiotherapy (PRT) may reduce radiation-associated endocrine dysfunction but clinical data are limited. Methods Seventy-seven children were treated with chemotherapy and proton (n = 40) or photon (n = 37) radiation between 2000 and 2009 with ≥3 years of endocrine… Continue reading Endocrine outcomes with proton and photon radiotherapy for standard risk medulloblastoma
Mitotic index, microvascular proliferation, and necrosis define 3 pathological subgroups of prognostic relevance among 1p/19q co-deleted anaplastic oligodendrogliomas
from #Oncology via alexandrossfakianakis on Inoreader http://ift.tt/1T72VU4 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/23JJMJl via IFTTT
Homeobox C9 suppresses Beclin1-mediated autophagy in glioblastoma by directly inhibiting the transcription of death-associated protein kinase 1
Background The transcription factor homeobox C9 (HOXC9) plays a crucial role in developmental regulatory systems, where it determines the specific positional identities of cells along the anteroposterior axis. The expression of HOXC9 has been found to be dysregulated in some cancers such as lung cancer, breast cancer, and neuroblastoma. Here, we report for the first… Continue reading Homeobox C9 suppresses Beclin1-mediated autophagy in glioblastoma by directly inhibiting the transcription of death-associated protein kinase 1
Epilepsy in glioma patients: mechanisms, management, and impact of anticonvulsant therapy
Seizures are a well-recognized symptom of primary brain tumors, and anticonvulsant use is common. This paper provides an overview of epilepsy and the use of anticonvulsants in glioma patients. Overall incidence and mechanisms of epileptogenesis are reviewed. Factors to consider with the use of antiepileptic drugs (AEDs) including incidence during the disease trajectory and prophylaxis… Continue reading Epilepsy in glioma patients: mechanisms, management, and impact of anticonvulsant therapy
Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis
Background Glioblastoma (GBM) is the most common malignant brain tumor, and glioma stem cells (GSCs) are considered a major source of treatment resistance for glioblastoma. Identifying new compounds that inhibit the growth of GSCs and understanding their underlying molecular mechanisms are therefore important for developing novel therapy for GBM. Methods We investigated the potential inhibitory… Continue reading Isorhapontigenin suppresses growth of patient-derived glioblastoma spheres through regulating miR-145/SOX2/cyclin D1 axis
Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups
Background Choroid plexus tumors are intraventricular neoplasms derived from the choroid plexus epithelium. A better knowledge of molecular factors involved in choroid plexus tumor biology may aid in identifying patients at risk for recurrence. Methods Methylation profiles were examined in 29 choroid plexus papillomas (CPPs, WHO grade I), 32 atypical choroid plexus papillomas (aCPPs, WHO… Continue reading Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups
A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy
Background Fatigue is common among glioma patients undergoing radiotherapy (RT) and impacts quality of life (QOL). We evaluated whether armodafinil, a wakefulness-promoting medication, improves fatigue in glioma patients undergoing RT. Methods Eligibility criteria included age ≥18 years, Karnofsky performance status ≥60, and grade 2–4 glioma undergoing RT to a total dose of 50–60 Gy. Patients… Continue reading A randomized, placebo-controlled pilot trial of armodafinil for fatigue in patients with gliomas undergoing radiotherapy
Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization
Background Glioblastoma (GBM) may initially respond to treatment with ionizing radiation (IR), but the prognosis remains extremely poor because the tumors invariably recur. Using animal models, we previously showed that inhibiting stromal cell–derived factor 1 signaling can prevent or delay GBM recurrence by blocking IR-induced recruitment of myeloid cells, specifically monocytes that give rise to… Continue reading Colony stimulating factor 1 receptor inhibition delays recurrence of glioblastoma after radiation by altering myeloid cell recruitment and polarization
Plasma exosomal miR-21 and miR-181a differentiates follicular from papillary thyroid cancer.
*Plasma exosomal miR-21 and miR-181a differentiates follicular from papillary thyroid cancer.* Tumour Biol. 2016 May 11; Authors: Samsonov R, Burdakov V, Shtam T, Radzhabovа Z, Vasilyev D, Tsyrlina E, Titov S, Ivanov M, Berstein L, Filatov M, Kolesnikov N, Gil-Henn H, Malek A Abstract Thyroid cancer (TC) is the most common endocrine malignancy and its incidence has increased over the last few decades. As has been revealed by a number of studies, TC tissue's micro-RNA (miRNA) profile may reflect histological features and the clinical behavior of tumor. However, alteration of the ... περισσότερα »
Sub-Classification of Lateral Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma by Pathologic Criteria.
Related Articles *Sub-Classification of Lateral Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma by Pathologic Criteria.* PLoS One. 2015;10(7):e0133625 Authors: Jeon MJ, Kim WG, Jang EK, Choi YM, Song DE, Sung TY, Yoon JH, Chung KW, Hong SJ, Ryu JS, Han JM, Kim TY, Shong YK, Kim WB Abstract BACKGROUND: Lateral cervical lymph node (LCLN) metastasis, or pathologic N1b disease, is an important risk factor in papillary thyroid carcinoma (PTC). However, many patients have favorable prognosis even with pathologic N1b patients in clinical practice. The study aims to identif... περισσότερα »
The Author's Reply: 'Thyroid nodules diagnosed as follicular neoplasm: do not forget Doppler US and correlation to previous imaging findings'.
Related Articles *The Author's Reply: 'Thyroid nodules diagnosed as follicular neoplasm: do not forget Doppler US and correlation to previous imaging findings'.* Clin Endocrinol (Oxf). 2015 Aug;83(2):288 Authors: Chng CL, Kurzawinski TR, Beale T PMID: 25677653 [PubMed - indexed for MEDLINE] from pubmed: thyroid cancer http://ift.tt/1TH2jjT via IFTTT
CDKN2B, SLC19A3 and DLEC1 promoter methylation alterations in the bone marrow of patients with acute myeloid leukemia during chemotherapy.
*CDKN2B, SLC19A3 and DLEC1 promoter methylation alterations in the bone marrow of patients with acute myeloid leukemia during chemotherapy.* Exp Ther Med. 2016 May;11(5):1901-1907 Authors: Hong Q, Li Y, Chen X, Ye H, Tang L, Zhou A, Hu Y, Gao Y, Chen R, Xia Y, Duan S Abstract Previous studies have demonstrated that promoter hypermethylation of tumor suppressor genes contributes to the occurrence and development of acute myeloid leukemia (AML). However, the association of DNA methylation with chemotherapeutic outcomes remains unknown. In the present study, 15 patients with AML wer... περισσότερα »
A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett's Esophagus.
*A Molecular Clock Infers Heterogeneous Tissue Age Among Patients with Barrett's Esophagus.* PLoS Comput Biol. 2016 May;12(5):e1004919 Authors: Curtius K, Wong CJ, Hazelton WD, Kaz AM, Chak A, Willis JE, Grady WM, Luebeck EG Abstract Biomarkers that drift differentially with age between normal and premalignant tissues, such as Barrett's esophagus (BE), have the potential to improve the assessment of a patient's cancer risk by providing quantitative information about how long a patient has lived with the precursor (i.e., dwell time). In the case of BE, which is a metaplastic prec... περισσότερα »
The emerging role of immunotherapy in gastric and esophageal adenocarcinoma.
*The emerging role of immunotherapy in gastric and esophageal adenocarcinoma.* Future Oncol. 2016 May 11; Authors: Bockorny B, Pectasides E Abstract Gastric and esophageal adenocarcinomas are aggressive malignancies. Systemic therapy for these tumors relies primarily on cytotoxic chemotherapy but outcomes remain poor. In recent years, immunotherapy has emerged as a new, promising therapeutic approach for a variety of solid tumors. Characterization of gastroesophageal cancers has revealed genomic and immune features of these tumors that may predict response to immunotherapy. Inde... περισσότερα »
Waterpipe smoking and cancer: systematic review and meta-analysis.
*Waterpipe smoking and cancer: systematic review and meta-analysis.* Tob Control. 2016 May 10; Authors: Montazeri Z, Nyiraneza C, El-Katerji H, Little J Abstract OBJECTIVE: Although accumulating evidence suggests harmful effects of waterpipe smoking, there is limited information about its direct association with chronic diseases, notably cancer. We provide an up-to-date systematic review and meta-analysis of the association between waterpipe smoking and cancer. DATA SOURCES: Systematic search of articles indexed in main biomedical databases: Pubmed, EmBase, Google Scholar and Web ... περισσότερα »
Neoadjuvant therapy for advanced esophageal cancer: the impact on surgical management.
*Neoadjuvant therapy for advanced esophageal cancer: the impact on surgical management.* Gen Thorac Cardiovasc Surg. 2016 May 10; Authors: Ikebe M, Morita M, Yamamoto M, Toh Y Abstract Multidisciplinary therapies have been developed to prolong the survival of patients with resectable esophageal cancer. Worldwide, neoadjuvant therapy has become the standard treatment for locally advanced resectable esophageal cancer. In this article, we briefly review the clinical trials and meta-analyses of neoadjuvant therapy for advanced esophageal cancer. In Europe and the USA, neoadjuvant che...περισσότερα »
Relationship between Urbanization and Cancer Incidence in Iran Using Quantile Regression.
*Relationship between Urbanization and Cancer Incidence in Iran Using Quantile Regression.* Asian Pac J Cancer Prev. 2016;17 Spec No.:113-7 Authors: Momenyan S, Sadeghifar M, Sarvi F, Khodadost M, Mosavi-Jarrahi A, Ghaffari ME, Sekhavati E Abstract Quantile regression is an efficient method for predicting and estimating the relationship between explanatory variables and percentile points of the response distribution, particularly for extreme percentiles of the distribution. To study the relationship between urbanization and cancer morbidity, we here applied quantile regression. T...περισσότερα »
From Prague to Seattle: Improved Endoscopic Technique and Reporting Improves Outcomes in Patients with Barrett's Esophagus.
Related Articles *From Prague to Seattle: Improved Endoscopic Technique and Reporting Improves Outcomes in Patients with Barrett's Esophagus.* Dig Dis Sci. 2016 Jan;61(1):4-5 Authors: Brown J, Sharma P PMID: 26547758 [PubMed - indexed for MEDLINE] from pubmed: esophageal cancer http://ift.tt/1sghpY7 via IFTTT
Association between SNP309 and del1518 Polymorphism in MDM2 Homologue and Esophageal Squamous Cell Carcinoma Risk in Chinese Population of Shandong Province.
Related Articles *Association between SNP309 and del1518 Polymorphism in MDM2 Homologue and Esophageal Squamous Cell Carcinoma Risk in Chinese Population of Shandong Province.* Ann Clin Lab Sci. 2015;45(4):433-7 Authors: Zhang L, Zhu Z, Wu H, Wang K Abstract BACKGROUND: Murine double-minute 2 homologue (MDM2) is a key negative regulator of p53. Polymorphisms in the promoter region were shown to alter the gene activity and/or function, suggesting a possible role in carcinogenesis. OBJECTIVE AND METHOD: The current study aims to investigate the association of SNP309 and del1518 po...περισσότερα »
Systematic review with meta-analysis: effect of fibre supplementation on chronic idiopathic constipation in adults
Summary Background Chronic idiopathic constipation is a common symptom-based gastrointestinal disorder responsible for a substantial economic health service burden. Current guidelines recommend the use of fibre as a first-line treatment. Aim To investigate the effect of fibre (including prebiotic) supplementation on global symptom response, stool output, gut microbiota composition and adverse events in adults with chronic idiopathic constipation. Methods Medline, EmBase, Web of Science, Scopus and the Cochrane central register of controlled trials were searched through to Februa... περισσότερα »
Adding family history to faecal immunochemical testing increases the detection of advanced neoplasia in a colorectal cancer screening programme
Summary Background Faecal immunochemical testing (FIT) for colorectal cancer (CRC) screening has suboptimal sensitivity for detecting advanced neoplasia. To increase its performance, FIT could be combined with other risk factors. Aim To evaluate the incremental yield of a screening programme using a positive FIT or a CRC family history, to offer a diagnostic colonoscopy. Methods For this *post hoc* analysis, data were collected in the colonoscopy arm of a colonoscopy or colonography for screening study. In this study, 6600 randomly selected, asymptomatic men and women (50–75 yea... περισσότερα »
The Association Between Olfaction and Depression: A Systematic Review
Previous studies on the relationship between olfaction and depression have revealed mixed results. In addition, few have focused on the reciprocity of this association. The aim of this study is to combine depression and olfactory data in two separate patient populations to further understand their association. A systematic literature review was conducted using 3 online databases to identify studies correlating olfaction and depression in patients presenting with either primary depression or primary olfactory dysfunction. For the depressed population, weighted means and standard de... περισσότερα »
Journal of Neurology, Vol. 263, Issue 5 - New Issue Alert
If this email is not displayed correctly, please click here to read this table of contents online. New Issue Alert 05/12/2016 Dear Alexandros Sfakianakis, We are pleased to deliver your requested table of contents alert for *Journal of Neurology*. Volume 263 Number 5 is now available online. Important news Stay up to date! Explore our new Neurology website on springer.com and don't miss out on the latest products, special offers and services in the field. In this issue Review Mal de debarquement syndrome: a systematic review Angelique Van Ombergen, Vincent Van Rompaey, ... περισσότερα »
A preliminary study of how the viscosity of dietary fluids and videofluoroscopy fluids can be matched
Dysphagia from #Medicine via ola Kala on Inoreader http://ift.tt/1X3dXuW via IFTTT
IJERPH, Vol. 13, Pages 494: Prevention of Asbestos-Related Disease in Countries Currently Using Asbestos
More than 40 years of evaluation have consistently confirmed the carcinogenicity of asbestos in all of its forms. This notwithstanding, according to recent figures, the annual world production of asbestos is approximatively 2,000,000 tons. Currently, about 90% of world asbestos comes from four countries: Russia, China, Brazil and Kazakhstan; and the wide use of asbestos worldwide represents a global threat. The purpose of this paper is to present a review of the asbestos health impact and to discuss the role of epidemiological investigations in countries where asbestos is still us... περισσότερα »
Toxins, Vol. 8, Pages 144: Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor
[image: ag] The dermaseptin antimicrobial peptide family contains members of 27–34 amino acids in length that have been predominantly isolated from the skins/skin secretions of phyllomedusine leaf frogs. By use of a degenerate primer in Rapid amplification of cDNA ends (RACE) PCR designed to a common conserved domain within the 5′-untranslated regions of previously-characterized dermaseptin encoding cDNAs, two novel members of this peptide family, named dermaseptin-PD-1 and dermaseptin-PD-2, were identified in the skin secretion of the phyllomedusine frog, Pachymedusa dacnicolor. ...περισσότερα »
Sensors, Vol. 16, Pages 688: Particle and Photon Detection: Counting and Energy Measurement
Fundamental limits for photon counting and photon energy measurement are reviewed for CCD and CMOS imagers. The challenges to extend photon counting into the visible/nIR wavelengths and achieve energy measurement in the UV with specific read noise requirements are discussed. Pixel flicker and random telegraph noise sources are highlighted along with various methods used in reducing their contribution on the sensor's read noise floor. Practical requirements for quantum efficiency, charge collection efficiency, and charge transfer efficiency that interfere with photon counting perfo... περισσότερα »
Future Internet, Vol. 8, Pages 19: Computational Social Science, the Evolution of Policy Design and Rule Making in Smart Societies
[image: ag] In the last 20 years, the convergence of different factors—the rise of the complexity of science, the "data deluge" and the advances in information technologies—triggered a paradigm shift in the way we understand complex social systems and their evolution. Beyond shedding new light onto social dynamics, the emerging research area of Computational Social Science (CSS) is providing a new rationale for a more scientifically-grounded and effective policy design. The paper discusses the opportunities potentially deriving from the intersection between policy design issues and... περισσότερα »
Sensors, Vol. 16, Pages 670: Model-Driven Approach for Body Area Network Application Development
This paper introduces the sensor-networked IoT model as a prototype to support the design of Body Area Network (BAN) applications for healthcare. Using the model, we analyze the synergistic effect of the functional requirements (data collection from the human body and transferring it to the top level) and non-functional requirements (trade-offs between energy-security-environmental factors, treated as Quality-of-Service (QoS)). We use feature models to represent the requirements at the earliest stage for the analysis and describe a model-driven methodology to design the possible B... περισσότερα »
IJERPH, Vol. 13, Pages 493: Factors Affecting Parent’s Perception on Air Quality—From the Individual to the Community Level
[image: ag] The perception of air quality significantly affects the acceptance of the public of the government's environmental policies. The aim of this research is to explore the relationship between the perception of the air quality of parents and scientific monitoring data and to analyze the factors that affect parents' perceptions. Scientific data of air quality were obtained from Wuhan's environmental condition reports. One thousand parents were investigated for their knowledge and perception of air quality. Scientific data show that the air quality of Wuhan follows an improvi... περισσότερα »
Sustainability, Vol. 8, Pages 471: Wetland Transitions and Protection under Rapid Urban Expansion: A Case Study of Pearl River Estuary, China
Understanding wetland changes under urbanization is important for wetland management. In this study, net transition intensity (NTI) and total transition intensity (TTI) are presented to characterize wetland transitions based on spatial data obtained from Landsat satellite images of Pearl River estuary in South China. NTI is commonly used to represent changes in absolute amounts for each class of wetland, while TTI reflects the internal transition activities and amounts. The third index, the urbanization intensity index (UII), is used to investigate the intensity and velocity of ur... περισσότερα »
Nanomaterials, Vol. 6, Pages 89: Modification of the Interfacial Interaction between Carbon Fiber and Epoxy with Carbon Hybrid Materials
[image: ag] The mechanical properties of the hybrid materials and epoxy and carbon fiber (CF) composites were improved significantly as compared to the CF composites made from unmodified epoxy. The reasons could be attributed to the strong interfacial interaction between the CF and the epoxy composites for the existence of carbon nanomaterials. The microstructure and dispersion of carbon nanomaterials were characterized by transmission electron microscopy (TEM) and optical microscopy (OM). The results showed that the dispersion of the hybrid materials in the polymer was superior to...περισσότερα »
Metals, Vol. 6, Pages 110: Melt Processing and Characterization of Al-SiC Nanocomposite, Al, and Mg Foam Materials
In the present work, metallic foams of Al, Mg and an Al-SiC nanocomposite (MMNC) have been fabricated using a new manufacturing technique by employing melt infiltration assisted with an electromagnetic force. The aim of this investigation was to study and to develop a reliable manufacturing technique consisting of different types of metallic foams. In this technique, an electromagnetic force was used to assist the infiltration of Al-SiC slurry and of pure liquid metal into a leachable pattern of NaCl, thus providing perfect cellular structures with micro-sized porosities. A high f... περισσότερα »
Energies, Vol. 9, Pages 359: Techno-Economic Analysis of Integrating First and Second-Generation Ethanol Production Using Filamentous Fungi: An Industrial Case Study
[image: ag] The 2nd generation plants producing ethanol from lignocelluloses demand risky and high investment costs. This paper presents the energy- and economical evaluations for integrating lignocellulose in current 1st generation dry mill ethanol processes, using filamentous fungi. Dry mills use grains and have mills, liquefactions, saccharifications, fermentation, and distillation to produce ethanol, while their stillage passes centrifugation, and evaporation to recycle the water and dry the cake and evaporated syrup into animal feed. In this work, a bioreactor was considered ... περισσότερα »
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