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Simulating a Maxillary Radicular Cyst: Quick Diagnosis and Management:Abstract: Plasma cell tumors are lymphoid neoplastic proliferations of B cells. Multiple myeloma is the disseminated type of this disorder, while localized forms of plasma cell neoplasms are solitary plasmacytoma of bone that is...
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Comparison of Two Techniques for Lateral Ridge Augmentation in Mandible With Ramus Block Graft: Abstract: The purpose of this manuscript was to assess mandibular ramus block grafts used for augmentation of mandibular posterior segments, followed by subsequent implant placement. Twenty-four human subjects...
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Bilateral Incomplete Cleft Lip:Abstract: Patients with cleft palate and cleft lip have severe functional and aesthetic problems, if this deformity is not treated properly and in time, can also cause psychological and aesthetic problems to the patients. This study reports a case of a 22-year-old patient...
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Effect of an Tissue healing is a complex process involving several players such as cells and growth factors released from platelets upon activation. Today, platelet concentrates (PCs) are used in many different medical fields including oral, orthopaedic, and reconstructive surgery since they allow growth...
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Discussion of Effect of Reflection of
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Application Value of The aim of the study was to investigate the image quality of dual-energy computed tomography angiography (DECTA) using the selective photon shield (SPS) technique to diagnose intracranial aneurysms.Materials and Methods: : Eighty patients with a suspected intracranial aneurysm were...
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Evaluation of Objective: Morphological changes in patients subjected to surgical treatment to correct occlusal discrepancies may lead to various functional changes. The aim of the present study was to evaluate changes in lip closing force after surgically assisted rapid maxillary expansion in skeletally...
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Intranasal Extramucosal Access: A New Access for Lateral Osteotomy in Open Rhinoplasty:Background and Objective: Different accesses have been used to perform lateral osteotomies in rhinoplasty. All of them have some disadvantages. The aim of this paper was to report a new access to overcome drawbacks...
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Intranasal Extramucosal Access: A New Access for Lateral Osteotomy in Open Rhinoplasty: Background and Objective: Different accesses have been used to perform lateral osteotomies in rhinoplasty. All of them have some disadvantages. The aim of this paper was to report a new access to overcome drawbacks...
09:11
Effect of Field of View on Detection of Condyle Bone Defects Using Cone Beam Computed Tomography: Abstract: In maxillofacial imaging, cone beam computed tomography (CBCT) is currently the modality of choice for assessment of bony structures of the temporomandibular joint (TMJ). Factors affecting the...
09:10
Stain removal effect of novel papain- and bromelain-containing gels applied to enamel: AbstractObjectivesThe aims of the study are to prepare novel stain removal gel-based formulations containing papain or bromelain and to investigate their stain removal effect when applied to enamel.Materials and methodsExperimental...
09:09
Ultrasound mediated drug delivery: AbstractFor patients with ulcerative colitis, the most common form of inflammatory bowel disease (IBD), aminosalicylates such as mesalamine provide first line anti-inflammatory therapy. Since efficacy is related to tissue concentration, when administered as a rectal...
09:08
in human gingival epithelial cells: AbstractObjectiveDiabetes is often associated with increased prevalence and severity of periodontal disease. We hypothesized that gingival epithelial cells modify periodontal disease progression and predicted that hyperglycemia would activate an inflammatory response...
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in Japanese patients with oral squamous cell carcinomavia Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyPublication date: Available online 11 May 2016Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Yoshihiro Ohashi, Kenichi Kumagai, Yukinaga Miyata, Ryota...
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Injectable bioactive glass in the restoration of oral bone defect: OBJECTIVE: To explore the application value of injectable bioactive glass in the restoration of the oral bone defect.PATIENTS AND METHODS: This study included 58 consecutive patients with oral bone defect > 1 mm, these patients were...
09:06
… laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 2: proposed applications and treatment …JAEM Zecha, JE Raber-Durlacher, RG Nair… - … Care in Cancer, 2016 - Springer... Results PBM may have potential applications in the manage-...
09:02
Similar presentation of cervical lymphadenitis of different etiology in two siblingsvia Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyJerome A. Lindeboom, M.D., D.D.S., Ph.D, , W.H. Schreuder, M.D., D.D.S.Department of Oral and Maxillofacial Surgery, Academic Medical Center, Amsterdam...
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Clinical, Demographic and Radiographic Analysis of 82 Patients Affected by Florid Osseous Dysplasia: An International Collaborative Studyvia Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyPublication date: Available online 12 May 2016Source:Oral Surgery, Oral Medicine, Oral Pathology and...
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via Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologySource:Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologySoulafa Almazrooa, BDS, DMSca, Nada Binmadi, BDS, PhDa, Hanadi Khalifa, BDS, MDSa, Awatif Jamal,MD, FRCPCb, Mohamad H. Qari, MD, FRCPAc, Maisa O. Al-Sebaei, BDS, MS,...
08:57
How Accurate Is Information About Diagnosis and Management Of Temporomandibular Disorders On Dentist Websites?via Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyPublication date: Available online 12 May 2016Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s):...
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Biological and clinical aspects of different bone substitutes integration in oral surgery: a literature reviewvia Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyPublication date: Available online 12 May 2016Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s):...
08:56
after third molar extraction? A systematic review and meta-analysisvia Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyPublication date: Available online 11 May 2016Source:Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Eva Ramos, Joseba Santamaría, Gorka Santamaría,...
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of oncological defects: complications, recovery of sensitivity, and assessment of quality of life: Our aim was to compare pedicled and island nasolabial flaps used for reconstruction of oral defects in terms of postoperative complications, recovery of sensitivity, and quality of life. We organised a...
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in Han Chinese using cone beam computed tomographyvia Oral and Maxillofacial SurgeryPublication date: Available online 12 May 2016Source:International Journal of Oral and Maxillofacial SurgeryAuthor(s): N. Kong, M. Hui, F. Miao, H. Yuan, Y. Du, N. ChenThe aim of this study was to provide reference information...
08:55
Biomechanical evaluation of different fixation systems after Le Fort I osteotomy in polyurethane models of unilateral clefts: We compared the stability of three different titanium plate-and-screw fixation systems after Le Fort I osteotomy in polyurethane models of unilateral clefts. Thirty-six models...
08:54
Treatment of labial mucosal recession around maxillary anterior implants with Tenting screws, particulate allograft and xenogenic membrane: a case reportJ Oral Implantol. 2016 May 11;Authors: Le B, Borzabadi-Farahani AAbstract Soft tissue augmentation procedures are often performed to correct...
08:53
associated with Mandarin-speaking children with repaired cleft palatevia International Journal of Pediatric OtorhinolaryngologyPublication date: July 2016Source:International Journal of Pediatric Otorhinolaryngology, Volume 86Author(s): Chenghui Jiang, Bradley McPherson, Manwa L. NgPurposeTo examine...
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Efficacy of auditory-verbal therapy in children with hearing impairment: A systematic review from 1993 to 2015via International Journal of Pediatric OtorhinolaryngologyPublication date: July 2016Source:International Journal of Pediatric Otorhinolaryngology, Volume 86Author(s): Ramesh Kaipa, Michelle...
08:52
Modification of the submandibular gland transfer procedure:Objectives/HypothesisThe treatment for most advanced head and neck cancers (stage III and IV) usually includes radiation, and the most common side effect of this treatment modality is a permanent decrease in salivary production. Xerostomia is...
08:51
Outcomes and predictors ofObjectives/HypothesisTo examine the effect of and predict the success of type 1 laryngeal cleft (LC-1) augmentation through swallowing evaluations.Study DesignRetrospective chart analysis.MethodsSixty-eight patients with LC-1s underwent interarytenoid injection laryngoplasty...
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with fluorescently labeled peptide: Objectives/HypothesisAdditional intraoperative guidance could reduce the risk of iatrogenic injury during parotid gland cancer surgery. We evaluated the intraoperative use of fluorescently labeled nerve binding peptide NP41 to aid facial nerve identification and preservation...
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in Ukraine: Pilot Study: Condition: Thyroid CancerIntervention: Sponsor: National Cancer Institute (NCI)Background:- The Ukrainian Research Center for Radiation Medicine and the U.S. National Institutes of Health have been studying cancer risks and outcomes in individuals who participated in...
08:39
Multimodal Monitoring of Conditions: Squamous Carcinoma; Head and Neck Cancer; Anal Cancer; Lung Cancer; Esophageal Cancer; Cervix CancerIntervention: Sponsors: Umeå University; Lund UniversityPatients with squamous cell carcinoma of the head & neck, anal canal, cervix, esophagus...
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Identification of Morphological Characteristics to Predict Difficult Endotracheal Intubation Using a Flexible Fiberscope: Condition: IntubationIntervention: Device: Flexible fiberscopeSponsor: Centre hospitalier de l'Université de Montréal (CHUM)ArmsAssigned InterventionsExperimental: Intubation...
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Classification, diagnostic criteria and management of benign paroxysmal positional vertigovia Auris Nasus LarynxPublication date: Available online May 2016Source:Auris Nasus LarynxAuthor(s): Takao Imai, Noriaki Takeda, Tetsuo Ikezono, Kohichiro Shigeno, Masatsugu Asai, Yukio Watanabe, Mamoru SuzukiBenign...
08:37
Demystifying the Role of :To the Editor We read with interest the article “Oncologic and Functional Outcomes of Surgical and Nonsurgical Treatment of Advanced Squamous Cell Carcinoma of the Supraglottic Larynx” by Elegbede et al, and we congratulate the authors on their study. There are, however, some...
08:36
Dupilumab: Targeted Therapy for Chronic Rhinosinusitis With Polyps: This commentary on an article recently published in JAMA discusses the use of subcutaneous dupilumab in adults with chronic rhinosinusitis with polyps.JAMAEffect of Subcutaneous Dupilumab on Nasal Polyp Burden in Patients With Chronic...
08:35
Supraglottoplasty for Laryngomalacia With Obstructive Sleep Apnea: This meta-analysis quantifies the objective outcomes of supraglottoplasty for laryngomalacia with obstructive sleep apnea via polysomnography data in the pediatric population.Importance Surgical intervention is the main treatment alternative...
08:34
Use of Hearing Devices and Depressive Symptoms in Older Adults: This observational study investigates the association of treatment with a hearing aid or cochlear implant with depressive symptoms in older adults.Importance Hearing loss is a common health problem in older adults that is strongly associated...
08:34
The Modified Frailty Index and Prediction of Clavien-Dindo Grade IV: This analysis of American College of Surgeons National Surgical Quality Improvement Program data assesses the predictive value of the Modified Frailty Index for Clavien-Dindo grade IV and grade V after major head and neck oncologic...
08:33
Patient With Nasal Obstruction: A woman had chronic bilateral nasal congestion without facial pressure, pain, paresthesia, bleeding, dysphagia, or voice change; endoscopy demonstrated moderate mucosal edema, and computed tomography revealed a nasopharyngeal mass that appeared hypodense. What is your...
08:32
A Novel ENU-Induced Mutation in Myo6 Causes Vestibular Dysfunction and Deafness: by Elaine Y. M. Wong, Chelsea Y. Xu, Manisha Brahmachary, Pin-Xian XuMouse N-ethyl-N-nitrosourea (ENU) mutagenesis has generated many useful animal models for human diseases. Here we describe the identification of a novel...
08:32
Bedeutung des sekundär auftretenden Primärtumors bei einem zervikalen CUP-Syndrom: Laryngo-Rhino-OtolDOI: 10.1055/s-0042-100907Fragestellung: Ziel der vorgestellten retrospektiven Analyse ist es, die Bedeutung des Primärtumors bei Patienten mit einem zervikalen CUP-Syndrom nach Abschluss von Diagnostik...
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the impact on surgical management.:Gen Thorac Cardiovasc Surg. 2016 May 10;Authors: Ikebe M, Morita M, Yamamoto M, Toh YAbstract Multidisciplinary therapies have been developed to prolong the survival of patients with resectable esophageal cancer. Worldwide, neoadjuvant therapy has become the...
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The emerging role of Future Oncol. 2016 May 11;Authors: Bockorny B, Pectasides EAbstract Gastric and esophageal adenocarcinomas are aggressive malignancies. Systemic therapy for these tumors relies primarily on cytotoxic chemotherapy but outcomes remain poor. In recent years, immunotherapy has...
08:31
A Population-Based Study: AbstractBackground and aimsPrevious research on H. pylori epidemiology has mostly focused on adult populations. We have aimed to study H. pylori prevalence in all age groups including children and adolescents and to identify potential routes of transmission.MethodsSubjects from...
08:30
The influence of geranylgeraniol on microvessel sprouting after bisphosphonate substitution in an in vitro 3D-angiogenesis assay: AbstractObjectivesRecent studies focused on angiogenesis in the pathophysiology of bisphosphonate-associated osteonecrosis of the jaws (BP-ONJ) and identified geranylgeraniol...
08:30
Nondestructive evaluation of a new via Acta BiomaterialiaPublication date: Available online 11 May 2016Source:Acta BiomaterialiaAuthor(s): Alexander J. Neumann, Timothy Quinn, Stephanie J. BryantPhotopolymerizable and hydrolytically labile poly(ethylene glycol) (PEG) hydrogels formed from photo-clickable...
08:29
Comparisons between physics-based, engineering, and statistical learning models for outdoor sound propagationMany outdoor sound propagationmodels exist, ranging from highly complex physics-based simulations to simplified engineering calculations, and more recently, highly flexible statistical learning...
08:28
A Novel ENU-Induced Mutation in Myo6 Causes Vestibular Dysfunction and Deafness: by Elaine Y. M. Wong, Chelsea Y. Xu, Manisha Brahmachary, Pin-Xian XuMouse N-ethyl-N-nitrosourea (ENU) mutagenesis has generated many useful animal models for human diseases. Here we describe the identification of a novel...
08:28
Toronto: If you have experienced a ringing sound in your ear or hear sounds that others don’t detect, you may be suffering from tinnitus. Fortunately, there are many tinnitus treatment Toronto that can relieve or eliminate some or all of your symptoms. What are some of these options?Get Your Mind Off...
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Laryngo-Rhino-Otol DOI: 10.1055/s-0036-1582308 © Georg Thieme Verlag KG Stuttgart · New York Article in Thieme eJournals:Table of contents | Full text from #ORL via xlomafota13 on Inoreader http://ift.tt/1rIMfYJ via IFTTT
04:06
Laryngo-Rhino-Otol DOI: 10.1055/s-0042-100907 Fragestellung: Ziel der vorgestellten retrospektiven Analyse ist es, die Bedeutung des Primärtumors bei Patienten mit einem zervikalen CUP-Syndrom nach Abschluss von Diagnostik und Therapie zu ermitteln. Patienten/Methoden: In die Untersuchung wurden 36...
04:06
Laryngo-Rhino-Otol DOI: 10.1055/s-0036-1582307 © Georg Thieme Verlag KG Stuttgart · New York Article in Thieme eJournals:Table of contents | Full text from #ORL via xlomafota13 on Inoreader http://ift.tt/1rIMhjq via IFTTT
02:35
If you have experienced a ringing sound in your ear or hear sounds that others don't detect, you may be suffering from tinnitus. Fortunately, there are many tinnitus treatment Toronto that can relieve or eliminate some or all of your symptoms. What are some of these options? Get Your Mind Off of the...
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• 171 women provided daily ratings of depression, anxiety, and sleep for 2 weeks• Nightly sleep disturbance and daily mood symptoms form a positive feedback loop• The relationship between sleep disturbance and depression is particularly corrosive• A single night of short sleep alleviates anhedonic depression...
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• Medical claims were used to evaluate comorbidities in 9,312 narcolepsy subjects.• Comparisons were made using claims from a group of 46,559 matched controls.• All comorbidities studied were significantly more prevalent in narcolepsy patients.• The only exceptions were perinatal and pregnancy/childbirth-related...
The organization of spinal motor neurons in a monotreme is consistent with a six-region schema of the mammalian spinal cord
Abstract The motor neurons in the spinal cord of an echidna (*Tachyglossus aculeatus*) have been mapped in Nissl-stained sections from spinal cord segments defined by spinal nerve anatomy. A medial motor column of motor neurons is found at all spinal cord levels, and a hypaxial column is found at most levels. The organization of the motor neuron clusters in the lateral motor column of the brachial (C5 to T3) and crural (L2 to S3) limb enlargements is very similar to the pattern previously revealed by retrograde tracing in placental mammals, and the motor neuron clusters have been t... περισσότερα »
Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model
Abstract Musculoskeletal modelling has become a valuable tool with which to understand how neural, muscular, skeletal and other tissues are integrated to produce movement. Most musculoskeletal modelling work has to date focused on humans or their close relatives, with few examples of quadrupedal animal limb models. A musculoskeletal model of the mouse hindlimb could have broad utility for questions in medicine, genetics, locomotion and neuroscience. This is due to this species' position as a premier model of human disease, having an array of genetic tools for manipulation of the a...περισσότερα »
Age-related changes in the tooth–bone interface area of acrodont dentition in the chameleon
Abstract Chameleon teeth develop as individual structures at a distance from the developing jaw bone during the pre-hatching period and also partially during the post-hatching period. However, in the adult, all teeth are fused together and tightly attached to the jaw bone by mineralized attachment tissue to form one functional unit. Tooth to bone as well as tooth to tooth attachments are so firm that if injury to the oral cavity occurs, several neighbouring teeth and pieces of jaw can be broken off. We analysed age-related changes in chameleon acrodont dentition, where ankylosis r... περισσότερα »
Free-living gait characteristics in ageing and Parkinson’s disease: impact of environment and ambulatory bout length
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Gait is emerging as a powerful diagnostic and prognostic tool, and as a surrogate marker of disease progression for Parkinson's disease (PD). Accelerometer-based body worn monitors (BWMs) facilitate the measur... from #Rehabilitation via ola Kala on Inoreader http://ift.tt/1VVknNE via IFTTT
A biologically-inspired multi-joint soft exosuit that can reduce the energy cost of loaded walking
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Carrying load alters normal walking, imposes additional stress to the musculoskeletal system, and results in an increase in energy consumption and a consequent earlier onset of fatigue. This phenomenon is larg... from #Rehabilitation via ola Kala on Inoreader http://ift.tt/1T6o8xl via IFTTT
The organization of spinal motor neurons in a monotreme is consistent with a six-region schema of the mammalian spinal cord
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα
Abstract The motor neurons in the spinal cord of an echidna (*Tachyglossus aculeatus*) have been mapped in Nissl-stained sections from spinal cord segments defined by spinal nerve anatomy. A medial motor column of motor neurons is found at all spinal cord levels, and a hypaxial column is found at most levels. The organization of the motor neuron clusters in the lateral motor column of the brachial (C5 to T3) and crural (L2 to S3) limb enlargements is very similar to the pattern previously revealed by retrograde tracing in placental mammals, and the motor neuron clusters have been t... περισσότερα »
Revisiting the segmental organization of the human spinal cord
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 35 δευτερόλεπτα
Abstract In classic anatomic atlases, the spinal cord is standardly represented in its anatomical form with symmetrically emerging anterior and posterior roots, which at the level of the intervertebral foramen combine into the spinal nerves. The parts of the cord delimited by the boundaries of the roots are called segments or myelomeres. Associated with their regular repetitive appearance is the notion that the cord is segmentally organized. This segmental view is reinforced by clinical practice. Spinal cord roots innervate specific body parts. The level of cord trauma is diagnosed... περισσότερα »
Malignancy is associated with microcalcification and higher AP/T ratio in ultrasonography, but not with Hashimoto’s thyroiditis in histopathology in patients with thyroid nodules evaluated as Bethesda Category III (AUS/FLUS) in cytology
Abstract The predictors of malignancy are important for the decision of appropriate management in nodules with atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS). Our aim was to determine the ultrasonographical, clinical, and biochemical predictors of malignancy in these patients. A total of 427 patients with cytologically Bethesda Category III (AUS/FLUS) thyroid nodules were included in this retrospective study. We divided the nodules into two subgroups according to the histopathology as benign and malignant, and compared the preoperative...περισσότερα »
The true cost of thyroid surgery determined by a micro-costing approach
Abstract Whether the amount of the current DRG tariff for thyroid surgery covers its actual cost has been questioned. We estimated a reliable cost of thyroid surgery for a large Italian hospital. A micro-costing approach is used with data from the University Hospital "Umberto I," a large facility that conducts a high volume of thyroidectomy surgical procedures in the Lazio region. The direct costs of surgery and hospitalization for a total and a hemi-thyroidectomy were €4956 and €4673, respectively. When compared to the DRG tariff of €3340, total thyroidectomy was €1616 (48 %) more... περισσότερα »
Clinical Translation of a 'Click Labeled 18F-Octreotate Radioligand for Imaging Neuroendocrine Tumors
We conducted the first-in-human study of 18F-fluoroethyl triazole [Tyr3] octreotate (18F-FET-βAG-TOCA) in patients with neuroendocrine tumors (NETs) to evaluate biodistribution, dosimetry, and safety. Despite advances in clinical imaging, detection and quantification of NET activity remains a challenge, with no universally accepted imaging standard. Methods Nine patients were enrolled. Eight patients had sporadic NET and one had multiple endocrine neoplasia type 1 (MEN1) syndrome. Patients received 137-163MBq (mean 155.7± 8 MBq) of 18F-FET-βAG-TOCA. Safety data were obtained durin...περισσότερα »
Tyrosine Phosphorylation of FGFR3-TACC3
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 40 δευτερόλεπτα
Fibroblast growth factor receptors (FGFR) are critical for cell proliferation and differentiation. Mutation and/or translocation of FGFRs lead to aberrant signaling that often results in developmental syndromes or cancer growth. As sequencing of human tumors becomes more frequent, so does the detection of FGFR translocations and fusion proteins. The research conducted in this article examines a frequently identified fusion protein between FGFR3 and transforming acidic coiled-coil containing protein 3 (TACC3), frequently identified in glioblastoma, lung cancer, bladder cancer, oral... περισσότερα »
Radiation enhances immune response to anti-tumor antibodies
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
Interest in combining radiotherapy and immune checkpoint therapy is growing rapidly. In this study, we explored a novel combination of this type to augment anti-tumor immune responses in preclinical murine models of melanoma, neuroblastoma, and head and neck squamous cell carcinoma. Cooperative effects were observed with local radiotherapy and intratumoral injection of tumor-specific antibodies, arising in part from enhanced antibody-dependent cell-mediated cytotoxicity (ADCC). We could improve this response by combining radiation with intratumoral injection of an IL-2-linked tumo... περισσότερα »
Peritonitis following percutaneous gastrostomy tube insertions in children
Abstract Background Percutaneous retrograde gastrostomy has a high success rate, low morbidity, and can be performed under different levels of sedation or local anesthesia in children. Despite its favourable safety profile, major complications can occur. Few studies have examined peritonitis following percutaneous retrograde gastrostomy in children. Objective To identify potential risk factors and variables influencing the development and early diagnosis of peritonitis following percutaneous retrograde gastrostomy. Materials and methods We conducted a retrospective case–control ... περισσότερα »
Digital platform for improving non-radiologists’ and radiologists’ interpretation of chest radiographs for suspected tuberculosis — a method for supporting task-shifting in developing countries
Abstract Background Shifting X-ray interpretation to non-radiologists can help to address radiologist shortages in developing countries. Objective To determine the change in accuracy of non-radiologists and radiologists for the radiographic diagnosis of paediatric tuberculosis after a short skill-development course. Materials and methods Participants interpreted 15 paediatric chest radiographs before and after a 30-minute course using three possible responses: (1) diagnostic for tuberculosis, (2) abnormal but inconclusive for diagnosis of tuberculosis and (3) normal. We compared... περισσότερα »
Mitteilungen der DGKFO
from #Dental via xlomafota13 on Inoreader http://ift.tt/1OmO33M via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Intermuscular aponeuroses between the flexor muscles of the forearm and their relationships with the ulnar nerve
Abstract Introduction The aim of this study was to clarify the morphological characteristics of the intermuscular aponeurosis between the flexor carpi ulnaris (FCU) and flexor digitorum superficialis (FDS; IMAS), and that between the FCU and flexor digitorum profundus (FDP; IMAP), and their topographic relationships with the ulnar nerve. Materials and methods Fifty limbs of 38 adult cadavers were studied. Results The IMAS extended along the deep surface of the FCU adjoining the FDS, having the appearance of a ladder, giving off "steps" that decreased in width from superficial to... περισσότερα »
Relationship between APOE Genotype and Structural MRI Measures throughout Adulthood in the Study of Health in Pomerania Population-Based Cohort [ADULT BRAIN]
BACKGROUND AND PURPOSE: The presence of the *apolipoprotein E* 4 allele is the strongest sporadic Alzheimer disease genetic risk factor. We hypothesized that *apolipoprotein E* 4 carriers and noncarriers may already differ in imaging patterns in midlife. We therefore sought to identify the effect of *apolipoprotein E* genotype on brain atrophy across almost the entire adult age span by using advanced MR imaging–based pattern analysis. MATERIALS AND METHODS: We analyzed MR imaging scans of 1472 participants from the Study of Health in Pomerania (22–90 years of age). We studied th... περισσότερα »
MR Imaging in Spinocerebellar Ataxias: A Systematic Review [ADULT BRAIN]
BACKGROUND AND PURPOSE: Polyglutamine expansion spinocerebellar ataxias are autosomal dominant slowly progressive neurodegenerative diseases with no current treatment. MR imaging is the best-studied surrogate biomarker candidate for polyglutamine expansion spinocerebellar ataxias, though with conflicting results. We aimed to review quantitative central nervous system MR imaging technique findings in patients with polyglutamine expansion spinocerebellar ataxias and correlations with well-established clinical and molecular disease markers. MATERIALS AND METHODS: We searched MEDLI... περισσότερα »
Nonaneurysmal Perimesencephalic Hemorrhage Is Associated with Deep Cerebral Venous Drainage Anomalies: A Systematic Literature Review and Meta-Analysis [ADULT BRAIN]
BACKGROUND AND PURPOSE: Mechanisms underlying bleeding in nonaneurysmal perimesencephalic SAH remain unclear. Previous investigators have suggested a relationship between nonaneurysmal perimesencephalic SAH and primitive venous drainage of the basal vein of Rosenthal. We performed a meta-analysis to evaluate the relation between primitive basal vein of Rosenthal drainage and nonaneurysmal perimesencephalic SAH. MATERIALS AND METHODS: We performed a comprehensive literature search of all studies examining the prevalence of primitive basal vein of Rosenthal drainage in patients wi... περισσότερα »
Peritherapeutic Hemodynamic Changes of Carotid Stenting Evaluated with Quantitative DSA in Patients with Carotid Stenosis [EXTRACRANIAL VASCULAR]
BACKGROUND AND PURPOSE: Quantitative data from DSA have become important tools for understanding hemodynamic changes of intracranial lesions. In this study, we evaluated 8 hemodynamic parameters in patients before and after carotid artery angioplasty. MATERIALS AND METHODS: DSA images of 34 patients with carotid stenosis who underwent angioplasty and stent placement were retrospectively analyzed. Eleven ROIs (M1, M2, A1, A2, the parietal vein, superior sagittal sinus, internal jugular vein, and 4 in the ICA) were selected on color-coded DSA. Eight hemodynamic parameters (bolus ... περισσότερα »
Differentiating Hemangioblastomas from Brain Metastases Using Diffusion-Weighted Imaging and Dynamic Susceptibility Contrast-Enhanced Perfusion-Weighted MR Imaging [ADULT BRAIN]
BACKGROUND AND PURPOSE: On DWI and DSC-PWI, hemangioblastomas and brain metastases may exhibit different signal intensities depending on their cellularity and angiogenesis. The purpose of this study was to evaluate whether a hemangioblastoma can be differentiated from a single brain metastasis with DWI and DSC-PWI. MATERIALS AND METHODS: We retrospectively reviewed DWI, DSC-PWI, and conventional MR imaging of 21 patients with hemangioblastomas and 30 patients with a single brain metastasis. Variables of minimum ADC and relative ADC were acquired by DWI and the parameter of rela... περισσότερα »
"Finding a Voice": Imaging Features after Phonosurgical Procedures for Vocal Fold Paralysis [HEAD & NECK]
SUMMARY: Altered communication (hoarseness, dysphonia, and breathy voice) that can result from vocal fold paralysis, secondary to numerous etiologies, may be amenable to surgical restoration. In this article, both traditional and cutting-edge phonosurgical procedures targeting the symptoms resulting from vocal fold paralysis are reviewed, with emphasis on the characteristic imaging appearances of various injectable materials, implants, and augmentation procedures used in the treatment of vocal fold paralysis. In addition, complications of injection laryngoplasty and medialization... περισσότερα »
Antiangiogenic Effect of Bevacizumab: Application of Arterial Spin-Labeling Perfusion MR Imaging in a Rat Glioblastoma Model [FUNCTIONAL]
BACKGROUND AND PURPOSE: The usefulness of arterial spin-labeling for the evaluation of the effect of the antiangiogenic therapy has not been elucidated. Our aim was to evaluate the antiangiogenic effect of bevacizumab in a rat glioblastoma model based on arterial spin-labeling perfusion MR imaging. MATERIALS AND METHODS: DSC and arterial spin-labeling perfusion MR imaging were performed by using a 9.4T MR imaging scanner in nude rats with glioblastoma. Rats were randomly assigned to the following 3 groups: control, 3-day treatment, and 10-day treatment after bevacizumab injectio...περισσότερα »
Relationship between APOE Genotype and Structural MRI Measures throughout Adulthood in the Study of Health in Pomerania Population-Based Cohort [ADULT BRAIN]
BACKGROUND AND PURPOSE: The presence of the *apolipoprotein E* 4 allele is the strongest sporadic Alzheimer disease genetic risk factor. We hypothesized that *apolipoprotein E* 4 carriers and noncarriers may already differ in imaging patterns in midlife. We therefore sought to identify the effect of *apolipoprotein E* genotype on brain atrophy across almost the entire adult age span by using advanced MR imaging–based pattern analysis. MATERIALS AND METHODS: We analyzed MR imaging scans of 1472 participants from the Study of Health in Pomerania (22–90 years of age). We studied th... περισσότερα »
MR Imaging in Spinocerebellar Ataxias: A Systematic Review [ADULT BRAIN]
BACKGROUND AND PURPOSE: Polyglutamine expansion spinocerebellar ataxias are autosomal dominant slowly progressive neurodegenerative diseases with no current treatment. MR imaging is the best-studied surrogate biomarker candidate for polyglutamine expansion spinocerebellar ataxias, though with conflicting results. We aimed to review quantitative central nervous system MR imaging technique findings in patients with polyglutamine expansion spinocerebellar ataxias and correlations with well-established clinical and molecular disease markers. MATERIALS AND METHODS: We searched MEDLI... περισσότερα »
Mitteilungen der DGKFO
from #Dental via xlomafota13 on Inoreader http://ift.tt/1OmO33M via IFTTT
Synchronous metastatic squamous cell carcinoma to the colon and cervical lymph nodes from a carcinoma of unknown primary site: A case report
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
Metastatic squamous cell carcinoma (SCC) from an unknown primary site to the colon has not been reported previously. A 75-year-old woman presented with a mass in the left submandibular region. Biopsy revealed a Class V lesion, but the histologic type was undetermined. Surgical resection of the left submandibular gland with cervical lymph node dissection was performed. However, SCC was seen in the lymph nodes only, with no tumor in the submandibular gland. Three months after surgery, computed tomography revealed that the preoperatively diagnosed lesion in the transverse colon had g...περισσότερα »
Measurement for improvement in anaesthesia and intensive care
from Anaesthesia via ola Kala on Inoreader http://ift.tt/1UXu1Ox via IFTTT
Nonaneurysmal Perimesencephalic Hemorrhage Is Associated with Deep Cerebral Venous Drainage Anomalies: A Systematic Literature Review and Meta-Analysis [ADULT BRAIN]
BACKGROUND AND PURPOSE: Mechanisms underlying bleeding in nonaneurysmal perimesencephalic SAH remain unclear. Previous investigators have suggested a relationship between nonaneurysmal perimesencephalic SAH and primitive venous drainage of the basal vein of Rosenthal. We performed a meta-analysis to evaluate the relation between primitive basal vein of Rosenthal drainage and nonaneurysmal perimesencephalic SAH. MATERIALS AND METHODS: We performed a comprehensive literature search of all studies examining the prevalence of primitive basal vein of Rosenthal drainage in patients wi... περισσότερα »
Peritherapeutic Hemodynamic Changes of Carotid Stenting Evaluated with Quantitative DSA in Patients with Carotid Stenosis [EXTRACRANIAL VASCULAR]
BACKGROUND AND PURPOSE: Quantitative data from DSA have become important tools for understanding hemodynamic changes of intracranial lesions. In this study, we evaluated 8 hemodynamic parameters in patients before and after carotid artery angioplasty. MATERIALS AND METHODS: DSA images of 34 patients with carotid stenosis who underwent angioplasty and stent placement were retrospectively analyzed. Eleven ROIs (M1, M2, A1, A2, the parietal vein, superior sagittal sinus, internal jugular vein, and 4 in the ICA) were selected on color-coded DSA. Eight hemodynamic parameters (bolus ... περισσότερα »
Program Manager II (EMS Director) - Louisiana Department of Health and Hospitals//HRTSD
Director of Emergency Medical Services for the State Department of Health and Hospitals (Louisiana) Plans, prepares and implements strategic long and short-term goals and objectives of the statewide program(s). Oversees statewide program compliance with state/federal laws and regulations. Organizes, schedules and coordinates all statewide monitoring and surveillance procedures; evaluates preparedness ... from EMS via xlomafota13 on Inoreader http://ift.tt/1siXRCv
Operations Chief - Greece Volunteer Ambulance Service, Inc.
Operations Chief (OC) is a paid position that has the primary responsibility of growing and managing the Greece Volunteer Ambulance (GVA) business and reports to the Board of Directors. The OC ha overall responsibility for all operations of GVA, including the supervision of employees and maintenance of a positive income ratio. The OC oversees the Operations Officers who are responsible for the day to ... from EMS via xlomafota13 on Inoreader http://ift.tt/1X5AvuU
The RevoLix™ 2 μm Continuous Wave Laser Vaporesection for the Treatment of Benign Prostatic Hyperplasia: Five Year Follow-Up
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1Xo8grR via IFTTT
Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model
Abstract Musculoskeletal modelling has become a valuable tool with which to understand how neural, muscular, skeletal and other tissues are integrated to produce movement. Most musculoskeletal modelling work has to date focused on humans or their close relatives, with few examples of quadrupedal animal limb models. A musculoskeletal model of the mouse hindlimb could have broad utility for questions in medicine, genetics, locomotion and neuroscience. This is due to this species' position as a premier model of human disease, having an array of genetic tools for manipulation of the a...περισσότερα »
Age-related changes in the tooth–bone interface area of acrodont dentition in the chameleon
Abstract Chameleon teeth develop as individual structures at a distance from the developing jaw bone during the pre-hatching period and also partially during the post-hatching period. However, in the adult, all teeth are fused together and tightly attached to the jaw bone by mineralized attachment tissue to form one functional unit. Tooth to bone as well as tooth to tooth attachments are so firm that if injury to the oral cavity occurs, several neighbouring teeth and pieces of jaw can be broken off. We analysed age-related changes in chameleon acrodont dentition, where ankylosis r... περισσότερα »
Effects on Bone Tissue After Osteotomy with Different High-Energy Lasers: An Ex Vivo Study
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1TdZ4mV via IFTTT
The RevoLix™ 2 μm Continuous Wave Laser Vaporesection for the Treatment of Benign Prostatic Hyperplasia: Five Year Follow-Up
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1Xo8ejH via IFTTT
Effects on Bone Tissue After Osteotomy with Different High-Energy Lasers: An Ex Vivo Study
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1TdZ3zp via IFTTT
A randomized double-blind multi-center trial of hydrogen water for Parkinson’s disease: protocol and baseline characteristics
Our previous randomized double-blind study showed that drinking hydrogen (H2) water for 48 weeks significantly improved the total Unified Parkinson's Disease Rating Scale (UPDRS) score of Parkinson's disease (PD)... from Neurology via xlomafota13 on Inoreader http://ift.tt/1UXw7hn via IFTTT
Neuroimaging basis in the conversion of aMCI patients with APOE-ε4 to AD: study protocol of a prospective diagnostic trial
The ε4 allele of the Apolipoprotein E gene (APOE-ε4) is a potent genetic risk factor for sporadic Alzheimer's disease (AD). Amnestic mild cognitive impairment (aMCI) is an intermediate state between normal cog... from Neurology via xlomafota13 on Inoreader http://ift.tt/222S8fV via IFTTT
The RevoLix™ 2 μm Continuous Wave Laser Vaporesection for the Treatment of Benign Prostatic Hyperplasia: Five Year Follow-Up
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1sj1EQd via IFTTT
The Cognition and Affect after Stroke - a Prospective Evaluation of Risks (CASPER) study: rationale and design
Cognitive impairment and neuropsychiatric syndromes, like depression and apathy, are frequent residual consequences of stroke. These have a large impact on quality of life and long-term prognosis. Several fact... from Neurology via xlomafota13 on Inoreader http://ift.tt/1UXw3yf via IFTTT
Effects on Bone Tissue After Osteotomy with Different High-Energy Lasers: An Ex Vivo Study
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1ZLfPrl via IFTTT
Measurement for improvement in anaesthesia and intensive care
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1UXu1Ox via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Musculoskeletal modelling has become a valuable tool with which to understand how neural, muscular, skeletal and other tissues are integrated to produce movement. Most musculoskeletal modelling work has to date focused on humans or their close relatives, with few examples of quadrupedal animal limb models. A musculoskeletal model of the mouse hindlimb could have […]
Age-related changes in the tooth–bone interface area of acrodont dentition in the chameleon
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Chameleon teeth develop as individual structures at a distance from the developing jaw bone during the pre-hatching period and also partially during the post-hatching period. However, in the adult, all teeth are fused together and tightly attached to the jaw bone by mineralized attachment tissue to form one functional unit. Tooth to bone as […]
PI3K p110β isoform synergizes with JNK in the regulation of glioblastoma cell proliferation and migration through Akt and FAK inhibition
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Glioblastoma multiforme is the most aggressive malignant primary brain tumor, characterized by rapid growth and extensive infiltration to neighboring normal brain parenchyma. Both PI3K/Akt and JNK pathways are… from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/23M09Fh via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The unfolded protein response: mechanisms and therapy of neurodegeneration
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Activation of the unfolded protein response is emerging as a common theme in protein-misfolding neurodegenerative diseases, with relevant markers observed in patient tissue and mouse models. Genetic and pharmacological manipulation of the pathway in several mouse models has shown that this is not a passive consequence of the neurodegeneration process. Rather, overactivation of the protein […]
TWiP 109: Blame it on Mother
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Daniel and Vincent solve the case of the Truck Driver from India, discuss why parasites resistant to an antimalarial drug are not transmitted by mosquitoes, and introduce Paul who presents a new case study. Hosts: from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1WtiFnb via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & […]
Osteoporosis in patients with stroke: A cross-sectional study
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Snezana Tomasevic-Todorovic, Dusica Simic-Panic, Aleksandar Knezevic, Cila Demesi-Drljan, Dusan Maric, Fahad Hanna Annals of Indian Academy of Neurology 2016 19(2):286-288 from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1WtlFjF via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Understanding migraine: Potential role of neurogenic inflammation
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Rakesh Malhotra Annals of Indian Academy of Neurology 2016 19(2):175-182 Neurogenic inflammation, a well-defined pathophysiologial process is characterized by the release of potent vasoactive neuropeptides, predominantly calcitonin gene-related peptide (CGRP), substance P (SP), and neurokinin A from activated peripheral nociceptive sensory nerve terminals (usually C and A delta-fibers). These peptides lead to a cascade of […]
Atypical magnetic resonance imaging features in subacute sclerosing panencephalitis
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Biplab Das, Manoj Kumar Goyal, Manish Modi, Sahil Mehta, Sudheer Chakravarthi, Vivek Lal, Sameer Vyas Annals of Indian Academy of Neurology 2016 19(2):275-276 Objectives: Subacute sclerosing panencephalitis (SSPE) is rare chronic, progressive encephalitis that affects primarily children and young adults, caused by a persistent infection with measles virus. No cure for SSPE exists, but the […]
Approach to a case of myeloneuropathy
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Ravindra Kumar Garg, Hardeep Singh Malhotra, Neeraj Kumar Annals of Indian Academy of Neurology 2016 19(2):183-187 Myeloneuropathy is a frequently encountered condition and often poses a diagnostic challenge. A variety of nutritional, toxic, metabolic, infective, inflammatory, and paraneoplastic disorders can present with myeloneuropathy. Deficiencies of vitamin B12, folic acid, copper, and vitamin E may lead […]
Mutation screening of the TPO gene in a cohort of 192 Chinese patients with congenital hypothyroidism
Objectives Defects in the human thyroid peroxidase (*TPO*) gene are reported to be one of the causes of congenital hypothyroidism (CH) due to dyshormonogenesis. The aim of this study was to examine the *TPO* mutation spectrum and prevalence among patients with CH in the Guangxi Zhuang Autonomous Region of China and to define the relationships between *TPO* genotypes and clinical phenotypes. Methods Blood samples were collected from 192 patients with CH in the Guangxi Zhuang Autonomous Region, China and genomic DNA was extracted from peripheral blood leucocytes. All exons of the... περισσότερα »
Copeptin predicts 10-year all-cause mortality in community patients: a 10-year prospective cohort study
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM) Issue: Ahead of print from #Medicine via ola Kala on Inoreader http://ift.tt/1Oqkits via IFTTT
Dopant Enriched Nitrogen Gas Combined with Sheathless Capillary Electrophoresis–Electrospray Ionization-Mass Spectrometry for Improved Sensitivity and Repeatability in Glycopeptide Analysis
[image: TOC Graphic] Analytical Chemistry DOI: 10.1021/acs.analchem.6b00479 [image: ancham?d=yIl2AUoC8zA] from #Medicine via ola Kala on Inoreader http://ift.tt/1rIQ0NH via IFTTT
Attention Deficit Hyperactivity Disorder in Pediatric Patients with Pheochromocytoma and Paraganglioma
Horm Metab Res DOI: 10.1055/s-0042-106725 The aim of the study is to evaluate if there is an association between attention deficit hyperactivity disorder (ADHD) and the diagnosis of pheochromocytoma/paraganglioma (PHEO/PGL) in pediatric patients. A case series study of 43 patients under the age of 18 with PHEO/PGL tumors who were evaluated at the National Institute of Health between January 2006 and May 2014 is reported. Prior diagnosis of ADHD and treatment course with stimulant medications was recorded. Patient symptoms, catecholamine and metanephrine levels, tumor characteristi...περισσότερα »
Expression of Estrogen Receptors Alpha (ER-α), Beta (ER-β), and G Protein-Coupled Receptor 30 (GPR30) in Testicular Tissue of Men with Klinefelter Syndrome
Horm Metab Res DOI: 10.1055/s-0042-105151 Men with Klinefelter syndrome (KS) present severe hormonal dysregulation, particularly elevated serum estradiol concentration. Estrogens act through specific receptors and regulate testes development and spermatogenesis. Herein, we evaluated GPR30, ERα, and ERβ mRNA expression in testis of KS men and men with 46XY karyotype by reverse transcriptase and quantitative PCR. ERβ transcripts are the most abundant in testicular tissue of 46XY men. Notably, testicular GPR30 transcription in KS men was approximately 12 times higher. Since GPR30 is ... περισσότερα »
Quantitative Determination and Subcellular Imaging of Cu in Single Cells via Laser Ablation-ICP-Mass Spectrometry Using High-Density Microarray Gelatin Standards
[image: TOC Graphic] Analytical Chemistry DOI: 10.1021/acs.analchem.6b00334 [image: ancham?d=yIl2AUoC8zA] from #Medicine via ola Kala on Inoreader http://ift.tt/1OmkbEL via IFTTT
Bone age assessment practices in infants and older children among Society for Pediatric Radiology members
Abstract Background Numerous bone age estimation techniques exist, but little is known about what methods radiologists use in clinical practice. Objective To determine which methods pediatric radiologists use to assess bone age in children, and their confidence in these methods. Materials and methods Society for Pediatric Radiology (SPR) members were invited to complete an online survey regarding bone age assessment. Respondents were asked to identify the methods used and their confidence with their technique for the following groups: Infants (<1 year old), 1- to 3-year-olds and ... περισσότερα »
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