Does monosodium glutamate really cause headache? : a systematic review of human studies
Although monosodium glutamate (MSG) is classified as a causative substance of headache in the International Classification of Headache Disorders 3rd edition (ICHD-III beta), there is no literature in which cau... from #Neuroscience via alexandrossfakianakis on Inoreader http://ift.tt/1XiBoAl via IFTTT
Endovanilloids are potential activators of the trigeminovascular nocisensor complex
In the dura mater encephali a significant population of trigeminal afferents coexpress the nociceptive ion channel transient receptor potential vanilloid type 1 (TRPV1) receptor and calcitonin gene-related pep... from #Neuroscience via alexandrossfakianakis on Inoreader http://ift.tt/1TXjqAZ via IFTTT
Progressive dysarthria and augmentative and alternative communication in conversation: establishing the reliability of the Dysarthria-in-Interaction Profile
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 10 δευτερόλεπτα
Abstract Background The Dysarthria-in-Interaction Profile’s potential contribution to the clinical assessment of dysarthria-in-conversation has been outlined in the literature, but its consistency of use across different users has yet to be reported. Aims To establish the level of consistency across raters on four different interaction categories. That is, how reliable clinicians are when rating a […]
Why Isn’t There More High-fidelity Simulation Training in Diagnostic Radiology? Results of a Survey of Academic Radiologists
Publication date: Available online 17 May 2016 Source:Academic Radiology Author(s): Tessa S. Cook, Jessica Hernandez, Mary Scanlon, Curtis Langlotz, Chun-Der L. Li Rationale and ObjectivesDespite its increasing use in training other medical specialties, high-fidelity simulation to prepare diagnostic radiology residents for call remains an underused educational resource. To attempt to characterize the barriers toward adoption… Continue reading Why Isn’t There More High-fidelity Simulation Training in Diagnostic Radiology? Results of a Survey of Academic Radiologists
Strange Supernova are Driven by Magnetic Fields Video
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Three animations model how strongly magnetized stars produce oddball stellar explosions
Penis operation highlights past, future of organ transplants – Fox News
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Fox News Penis operation highlights past, future of organ transplants Fox News CHICAGO (AP) — Add one remarkable case to the 30,000-plus organ transplants expected to be performed nationwide this year: a cancer patient who received a donor penis. Worldwide, there have been faces, tongues, hands, legs, uteruses – and now the … and more […]
IJMS, Vol. 17, Pages 702: Understanding the Functions of Long Non-Coding RNAs through Their Higher-Order Structures
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Although thousands of long non-coding RNAs (lncRNAs) have been discovered in eukaryotes, very few molecular mechanisms have been characterized due to an insufficient understanding of lncRNA structure. Therefore, investigations of lncRNA structure and subsequent elucidation of the regulatory mechanisms are urgently needed. However, since lncRNA are high molecular weight molecules, which makes their crystallization difficult, […]
IJMS, Vol. 17, Pages 746: “Fifty Shades” of Black and Red or How Carboxyl Groups Fine Tune Eumelanin and Pheomelanin Properties
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Recent advances in the chemistry of melanins have begun to disclose a number of important structure-property-function relationships of crucial relevance to the biological role of human pigments, including skin (photo) protection and UV-susceptibility. Even slight variations in the monomer composition of black eumelanins and red pheomelanins have been shown to determine significant differences in light […]
IJMS, Vol. 17, Pages 743: Clinical and Molecular Characterization of Patients with Mucopolysaccharidosis Type I in an Algerian Series
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
Mucopolysaccharidoses (MPS’s) represent a subgroup of lysosomal storage diseases related to a deficiency of enzymes that catalyze glycosaminoglycans degradation. Mucopolysaccharidosis type I (MPS I) is a rare autosomal recessive disorder caused by a deficiency of α-l-iduronidase encoded by the IDUA gene. Partially degraded heparan sulfate and dermatan sulfate accumulate progressively and lead to multiorgan dysfunction […]
IJMS, Vol. 17, Pages 750: Long-Term Follow-up of HPV Infection Using Urine and Cervical Quantitative HPV DNA Testing
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
The link between infection with high-risk human papillomavirus (hrHPV) and cervical cancer has been clearly demonstrated. Virological end-points showing the absence of persistent HPV infection are now accepted as a way of monitoring the impact of prophylactic vaccination programs and therapeutic vaccine trials. This study investigated the use of urine samples, which can be collected […]
IJMS, Vol. 17, Pages 744: Postprandial C-Peptide to Glucose Ratio as a Marker of β Cell Function: Implication for the Management of Type 2 Diabetes
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 13 δευτερόλεπτα
C-peptide is secreted from pancreatic β cells at an equimolar ratio to insulin. Since, in contrast to insulin, C-peptide is not extracted by the liver and other organs, C-peptide reflects endogenous insulin secretion more accurately than insulin. C-peptide is therefore used as a marker of β cell function. C-peptide has been mainly used to assess […]
IJMS, Vol. 17, Pages 676: A Novel Prostate-Specific Membrane-Antigen (PSMA) Targeted Micelle-Encapsulating Wogonin Inhibits Prostate Cancer Cell Proliferation via Inducing Intrinsic Apoptotic Pathway
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 17 δευτερόλεπτα
Prostate cancer (PCa) is a malignant tumor for which there are no effective treatment strategies. In this study, we developed a targeted strategy for prostate-specific membrane-antigen (PSMA)-positive PCa in vitro based on 2-(3-((S)-5-amino-1-carboxypentyl)ureido) pentanedioic acid (ACUPA) modified polyethylene glycol (PEG)-Cholesterol micelles containing wogonin (WOG), which was named ACUPA-M-WOG. ACUPA-M-WOG was conventionally prepared using a self-assembling […]
IJMS, Vol. 17, Pages 745: In Vitro Activity of Copper(II) Complexes, Loaded or Unloaded into a Nanostructured Lipid System, against Mycobacterium tuberculosis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 17 δευτερόλεπτα
Tuberculosis (TB) is an infectious disease caused mainly by the bacillus Mycobacterium tuberculosis (Mtb), presenting 9.5 million new cases and 1.5 million deaths in 2014. The aim of this study was to evaluate a nanostructured lipid system (NLS) composed of 10% phase oil (cholesterol), 10% surfactant (soy phosphatidylcholine, sodium oleate), and Eumulgin® HRE 40 ([castor […]
Primary immunodeficiency and recalcitrant chronic sinusitis: a systematic review
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Background A subset of patients with chronic rhinosinusitis (CRS) has disease refractory to standard therapies. Primary immunodeficiency should be considered in this group. Past literature has demonstrated an association between immunodeficiency and chronic sinusitis. Methods A systematic literature search was performed using OVID, MEDLINE, EMBASE, and Cochrane databases to identify English language papers containing original […]
IJMS, Vol. 17, Pages 702: Understanding the Functions of Long Non-Coding RNAs through Their Higher-Order Structures
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Although thousands of long non-coding RNAs (lncRNAs) have been discovered in eukaryotes, very few molecular mechanisms have been characterized due to an insufficient understanding of lncRNA structure. Therefore, investigations of lncRNA structure and subsequent elucidation of the regulatory mechanisms are urgently needed. However, since lncRNA are high molecular weight molecules, which makes their crystallization difficult, […]
IJMS, Vol. 17, Pages 746: “Fifty Shades” of Black and Red or How Carboxyl Groups Fine Tune Eumelanin and Pheomelanin Properties
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Recent advances in the chemistry of melanins have begun to disclose a number of important structure-property-function relationships of crucial relevance to the biological role of human pigments, including skin (photo) protection and UV-susceptibility. Even slight variations in the monomer composition of black eumelanins and red pheomelanins have been shown to determine significant differences in light […]
IJMS, Vol. 17, Pages 743: Clinical and Molecular Characterization of Patients with Mucopolysaccharidosis Type I in an Algerian Series
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Mucopolysaccharidoses (MPS’s) represent a subgroup of lysosomal storage diseases related to a deficiency of enzymes that catalyze glycosaminoglycans degradation. Mucopolysaccharidosis type I (MPS I) is a rare autosomal recessive disorder caused by a deficiency of α-l-iduronidase encoded by the IDUA gene. Partially degraded heparan sulfate and dermatan sulfate accumulate progressively and lead to multiorgan dysfunction […]
IJMS, Vol. 17, Pages 750: Long-Term Follow-up of HPV Infection Using Urine and Cervical Quantitative HPV DNA Testing
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
The link between infection with high-risk human papillomavirus (hrHPV) and cervical cancer has been clearly demonstrated. Virological end-points showing the absence of persistent HPV infection are now accepted as a way of monitoring the impact of prophylactic vaccination programs and therapeutic vaccine trials. This study investigated the use of urine samples, which can be collected […]
IJMS, Vol. 17, Pages 744: Postprandial C-Peptide to Glucose Ratio as a Marker of β Cell Function: Implication for the Management of Type 2 Diabetes
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
C-peptide is secreted from pancreatic β cells at an equimolar ratio to insulin. Since, in contrast to insulin, C-peptide is not extracted by the liver and other organs, C-peptide reflects endogenous insulin secretion more accurately than insulin. C-peptide is therefore used as a marker of β cell function. C-peptide has been mainly used to assess […]
IJMS, Vol. 17, Pages 676: A Novel Prostate-Specific Membrane-Antigen (PSMA) Targeted Micelle-Encapsulating Wogonin Inhibits Prostate Cancer Cell Proliferation via Inducing Intrinsic Apoptotic Pathway
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Prostate cancer (PCa) is a malignant tumor for which there are no effective treatment strategies. In this study, we developed a targeted strategy for prostate-specific membrane-antigen (PSMA)-positive PCa in vitro based on 2-(3-((S)-5-amino-1-carboxypentyl)ureido) pentanedioic acid (ACUPA) modified polyethylene glycol (PEG)-Cholesterol micelles containing wogonin (WOG), which was named ACUPA-M-WOG. ACUPA-M-WOG was conventionally prepared using a self-assembling […]
IJMS, Vol. 17, Pages 745: In Vitro Activity of Copper(II) Complexes, Loaded or Unloaded into a Nanostructured Lipid System, against Mycobacterium tuberculosis
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Tuberculosis (TB) is an infectious disease caused mainly by the bacillus Mycobacterium tuberculosis (Mtb), presenting 9.5 million new cases and 1.5 million deaths in 2014. The aim of this study was to evaluate a nanostructured lipid system (NLS) composed of 10% phase oil (cholesterol), 10% surfactant (soy phosphatidylcholine, sodium oleate), and Eumulgin® HRE 40 ([castor […]
Primary immunodeficiency and recalcitrant chronic sinusitis: a systematic review
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Background A subset of patients with chronic rhinosinusitis (CRS) has disease refractory to standard therapies. Primary immunodeficiency should be considered in this group. Past literature has demonstrated an association between immunodeficiency and chronic sinusitis. Methods A systematic literature search was performed using OVID, MEDLINE, EMBASE, and Cochrane databases to identify English language papers containing original […]
The Sally–Anne test: an interactional analysis of a dyadic assessment
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Abstract Background The Sally–Anne test has been extensively used to examine children’s theory of mind understanding. Many task-related factors have been suggested to impact children’s performance on this test. Yet little is known about the interactional aspects of such dyadic assessment situations that might contribute to the ways in which children respond to the test […]
Etiology of bone and joint infections: a case series of 363 consecutive patients from an orthopaedic infection unit
10.1080/23744235.2016.1183814<br>Katja Wallander from Infection via ola Kala on Inoreader http://ift.tt/1TkBIgA via IFTTT
NIH-funded study reveals how differences in male and female brains emerge
Nematode worms may not be from Mars or Venus, but they do have sex-specific circuits in their brains that cause the males and females to act differently. from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1WCqs1D via IFTTT
Primary immunodeficiency and recalcitrant chronic sinusitis: a systematic review
Background A subset of patients with chronic rhinosinusitis (CRS) has disease refractory to standard therapies. Primary immunodeficiency should be considered in this group. Past literature has demonstrated an association between immunodeficiency and chronic sinusitis. Methods A systematic literature search was performed using OVID, MEDLINE, EMBASE, and Cochrane databases to identify English language papers containing original… Continue reading Primary immunodeficiency and recalcitrant chronic sinusitis: a systematic review
A Heuristic Task Scheduling Algorithm for Heterogeneous Virtual Clusters
Cloud computing provides on-demand computing and storage services with high performance and high scalability. However, the rising energy consumption of cloud data centers has become a prominent problem. In this paper, we first introduce an energy-aware framework for task scheduling in virtual clusters. The framework consists of a task resource requirements prediction module, an energy… Continue reading A Heuristic Task Scheduling Algorithm for Heterogeneous Virtual Clusters
On Subordinations for Certain Multivalent Analytic Functions in the Right-Half Plane
The object of the present paper is to investigate some properties of multivalent analytic functions associated with the lemniscate of Bernoulli. from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1XwH36r via IFTTT
Psychometric Properties of the Persian Version of the Short Beck Depression Inventory with Iranian Psychiatric Outpatients
The short form of the Beck Depression Inventory (BDI-13) is useful for the screening and assessment of depression in clinical and research settings. The aim of the present study was to investigate the psychometric properties of the Persian (Farsi) version of BDI-13 in an Iranian clinical sample. The sample consisted of 52 Iranian psychiatric outpatients… Continue reading Psychometric Properties of the Persian Version of the Short Beck Depression Inventory with Iranian Psychiatric Outpatients
World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Vitamin D
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The prevalence of allergic diseases is approximately 10 % in infants whose parents and siblings do not have allergic diseases and 20–30 % in those with an allergic first-degree relative. Vitamin D is involved in … from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1ThNyog via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & […]
Small nuclear ribonucleoprotein polypeptide N (Sm51) promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating Runx2
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Small nuclear ribonucleoprotein-associated polypeptide N mutation in mice is associated with short limbs and lower bone mineral density, yet the role of Sm51 in MSC differentiation to osteoblasts is not known. In the present study, we investigate the role of Sm51 in regulating osteoblastic differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs). Stable overexpression […]
Morphological and behavioral characterization of adult mice deficient for SrGAP3
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract SrGAP3 belongs to the family of Rho GTPase proteins. These proteins are thought to play essential roles in development and in the plasticity of the nervous system. SrGAP3-deficient mice have recently been created and approximately 10 % of these mice developed a hydrocephalus and died shortly after birth. The others survived into adulthood, but […]
Identification and sexually dimorphic expression of vasa isoforms in Dabry′s sturgeon ( Acipenser dabryanus ), and functional analysis of vasa 3′-untranslated region
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Germ cells are set aside from somatic cells early in embryogenesis, and are responsible for transmitting genetic information through generations. Vasa is a highly conserved germ cell marker across animal phyla, and widely used to label primordial germ cells. Dabry’s sturgeon is a rare and endangered species distributed solely in the Yangtze River basin. […]
A tale of two orgins: do myofibroblasts originate from different sources in wound healing and fibrosis?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Oxygdb via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The effects of aging on the perception of depth from motion parallax
Abstract Successful navigation in the world requires effective visuospatial processing. Unfortunately, older adults have many visuospatial deficits, which can have severe real-world consequences. Although some of these age effects are well documented, some others, such as the perception of depth from motion parallax, are poorly understood. Depth perception from motion parallax requires intact retinal image motion and pursuit eye movement processing. Decades of research have shown that both motion processing and pursuit eye movements are affected by age; it follows that older adults...περισσότερα »
Value-modulated oculomotor capture by task-irrelevant stimuli is a consequence of early competition on the saccade map
Abstract Recent research has shown that reward learning can modulate oculomotor and attentional capture by physically salient and task-irrelevant distractor stimuli, even when directing gaze to those stimuli is directly counterproductive to receiving reward. This value-modulated oculomotor capture effect may reflect biased competition in the oculomotor system, such that the relationship between a stimulus feature and reward enhances that feature's representation on an internal priority map. However, it is also possible that this effect is a result of reward reducing the threshold ... περισσότερα »
Alignment effects in beer mugs: Automatic action activation or response competition?
Abstract Responses to objects with a graspable handle are faster when the response hand and handle orientation are aligned (e.g., a key press with the right hand is required and the object handle is oriented to the right) than when they are not aligned. This effect could be explained by automatic activation of specific motor programs when an object is viewed. Alternatively, the effect could be explained by competition at the response level. Participants performed a reach-and-grasp or reach-and-button-press action with their left or right hand in response to the color of a beer mug... περισσότερα »
Axon degeneration: context defines distinct pathways
[image: S09594388.gif] Publication date: August 2016 *Source:*Current Opinion in Neurobiology, Volume 39 Author(s): Matthew J Geden, Mohanish Deshmukh Axon degeneration is an essential part of development, plasticity, and injury response and has been primarily studied in mammalian models in three contexts: 1) Axotomy-induced Wallerian degeneration, 2) Apoptosis-induced axon degeneration (axon apoptosis), and 3) Axon pruning. These three contexts dictate engagement of distinct pathways for axon degeneration. Recent advances have identified the importance of SARM1, NMNATs, NAD+ deplet... περισσότερα »
Small nuclear ribonucleoprotein polypeptide N (Sm51) promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating Runx2
Abstract Small nuclear ribonucleoprotein-associated polypeptide N mutation in mice is associated with short limbs and lower bone mineral density, yet the role of Sm51 in MSC differentiation to osteoblasts is not known. In the present study, we investigate the role of Sm51 in regulating osteoblastic differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs). Stable overexpression of Sm51 in rat and human BM-MSCs (Sm51-MSCs) significantly enhanced their osteogenic differentiation potential compared to untransfected cells. Under osteogenic induction, Sm51-MSCs had higher ...περισσότερα »
Morphological and behavioral characterization of adult mice deficient for SrGAP3
Abstract SrGAP3 belongs to the family of Rho GTPase proteins. These proteins are thought to play essential roles in development and in the plasticity of the nervous system. SrGAP3-deficient mice have recently been created and approximately 10 % of these mice developed a hydrocephalus and died shortly after birth. The others survived into adulthood, but displayed neuroanatomical alteration, including increased ventricular size. We now show that SrGAP3-deficient mice display increased brain weight together with increased hippocampal volume. This increase was accompanied by an increa... περισσότερα »
Identification and sexually dimorphic expression of vasa isoforms in Dabry′s sturgeon ( Acipenser dabryanus ), and functional analysis of vasa 3′-untranslated region
Abstract Germ cells are set aside from somatic cells early in embryogenesis, and are responsible for transmitting genetic information through generations. Vasa is a highly conserved germ cell marker across animal phyla, and widely used to label primordial germ cells. Dabry's sturgeon is a rare and endangered species distributed solely in the Yangtze River basin. Here, seven *vasa* isoforms, named *Advasa1–7*, were isolated and characterized in Dabry's sturgeon. RT-PCR and western blot analyses revealed that *vasa* mRNA and protein were mainly restricted to the testis and ovary, but...περισσότερα »
A tale of two orgins: do myofibroblasts originate from different sources in wound healing and fibrosis?
from Cell via ola Kala on Inoreader http://ift.tt/1Oxygdb via IFTTT
Salivary Secretory Immunoglobulin (SIgA) and Lysozyme in Malignant Tumor Patients
Background. The purpose of this study is to understand the oral mucosal immune status of cancer patients and to make clear whether antibacterial proteins such as salivary secretory immunoglobulin (SIgA) and lysozyme in saliva were influenced by patients' health status and certain medical treatment therapy. Materials and Methods. This study included 221 patients with malignant tumor receiving antineoplastic treatment and 171 age- and gender-matched healthy controls. Results. The results showed that patients suffering malignant tumor had lower level of SIgA and higher level of lysoz...περισσότερα »
Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats
The present study was designed to investigate the cardioprotective effects of Sundarban honey (SH) in rats with isoproterenol- (ISO-) induced myocardial infarction. Adult male Wistar Albino rats were pretreated with Sundarban honey (5 g/kg) daily for a period of 6 weeks. After the treatment period, ISO (85 mg/kg) was subcutaneously injected into the rats at 24 h intervals for 2 days. ISO-induced myocardial damage was indicated by increased serum cardiac specific troponin I levels and cardiac marker enzyme activities including creatine kinase-MB, lactate dehydrogenase, aspartate tr...περισσότερα »
GSE70301 Expression data from oral squamous cell carcinoma cell line Cal27 after lentivirus shIL-1beta transfection
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
*Contributor* : Tong Wu *Series Type* : Expression profiling by array *Organism* : Homo sapiens Oral squamous cell carcinoma cell line Cal27 was transfected with lentiviral shIL-1beta or scrambled shRNA. We used microarrays to detail the global program of gene expression during this process. from squamous cell carcinoma via ok on Inoreader http://ift.tt/25av7Nm via IFTTT
Small nuclear ribonucleoprotein polypeptide N (Sm51) promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating Runx2
Abstract Small nuclear ribonucleoprotein-associated polypeptide N mutation in mice is associated with short limbs and lower bone mineral density, yet the role of Sm51 in MSC differentiation to osteoblasts is not known. In the present study, we investigate the role of Sm51 in regulating osteoblastic differentiation of bone marrow-derived mesenchymal stem cells (BM-MSCs). Stable overexpression… Continue reading Small nuclear ribonucleoprotein polypeptide N (Sm51) promotes osteogenic differentiation of bone marrow mesenchymal stem cells by regulating Runx2
Morphological and behavioral characterization of adult mice deficient for SrGAP3
Abstract SrGAP3 belongs to the family of Rho GTPase proteins. These proteins are thought to play essential roles in development and in the plasticity of the nervous system. SrGAP3-deficient mice have recently been created and approximately 10 % of these mice developed a hydrocephalus and died shortly after birth. The others survived into adulthood, but… Continue reading Morphological and behavioral characterization of adult mice deficient for SrGAP3
Identification and sexually dimorphic expression of vasa isoforms in Dabry′s sturgeon ( Acipenser dabryanus ), and functional analysis of vasa 3′-untranslated region
Abstract Germ cells are set aside from somatic cells early in embryogenesis, and are responsible for transmitting genetic information through generations. Vasa is a highly conserved germ cell marker across animal phyla, and widely used to label primordial germ cells. Dabry’s sturgeon is a rare and endangered species distributed solely in the Yangtze River basin.… Continue reading Identification and sexually dimorphic expression of vasa isoforms in Dabry′s sturgeon ( Acipenser dabryanus ), and functional analysis of vasa 3′-untranslated region
A tale of two orgins: do myofibroblasts originate from different sources in wound healing and fibrosis?
from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1Oxygdb via IFTTT
GSE81496 Arabidopsis lyrata gene annotation using RNA-sequencing data
Series Type : Expression profiling by high throughput sequencing Organism : Arabidopsis lyrata subsp. lyrata ; Arabidopsis thaliana This SuperSeries is composed of the SubSeries listed below. from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1TV9ntc via IFTTT
Efficacy and Safety of a Dexamethasone Implant in Patients with Diabetic Macular Edema at Tertiary Centers in Korea
Purpose. To evaluate the real-world efficacy and safety of the dexamethasone implant (DEX implant) in patients with diabetic macular edema (DME). Methods. Retrospective, multicenter, and noncomparative study of DME patients who were treated with at least one DEX implant. A total of 186 eyes from 165 patients were included. Best-corrected visual acuity (BCVA), central retinal… Continue reading Efficacy and Safety of a Dexamethasone Implant in Patients with Diabetic Macular Edema at Tertiary Centers in Korea
Cystatin C Falsely Underestimated GFR in a Critically Ill Patient with a New Diagnosis of AIDS
Cystatin C has been suggested to be a more accurate glomerular filtration rate (GFR) surrogate than creatinine in patients with acquired immunodeficiency syndrome (AIDS) because it is unaffected by skeletal muscle mass and dietary influences. However, little is known about the utility of this marker for monitoring medications in the critically ill. We describe the… Continue reading Cystatin C Falsely Underestimated GFR in a Critically Ill Patient with a New Diagnosis of AIDS
Evaluation of the Synergistic Effect of Erosion-Corrosion on AISI 4330 Steel in Saline-Sand Multiphase Flow by Electrochemical and Gravimetric Techniques
The synergistic effects of fluid flow, sand particles, and solution pH on erosion-corrosion of AISI 4330 steel alloy in saline-sand medium were studied through a rotating cylinder electrode (RCE) system by weight-loss and electrochemical measurements. The worn surface was analyzed by X-ray diffraction (XRD) and scanning electron microscopy (SEM). Results show that, under all the… Continue reading Evaluation of the Synergistic Effect of Erosion-Corrosion on AISI 4330 Steel in Saline-Sand Multiphase Flow by Electrochemical and Gravimetric Techniques
Salivary Secretory Immunoglobulin (SIgA) and Lysozyme in Malignant Tumor Patients
Background. The purpose of this study is to understand the oral mucosal immune status of cancer patients and to make clear whether antibacterial proteins such as salivary secretory immunoglobulin (SIgA) and lysozyme in saliva were influenced by patients’ health status and certain medical treatment therapy. Materials and Methods. This study included 221 patients with malignant… Continue reading Salivary Secretory Immunoglobulin (SIgA) and Lysozyme in Malignant Tumor Patients
Border Collision Bifurcations in a Generalized Model of Population Dynamics
We analyze the dynamics of a generalized discrete time population model of a two-stage species with recruitment and capture. This generalization, which is inspired by other approaches and real data that one can find in literature, consists in considering no restriction for the value of the two key parameters appearing in the model, that is,… Continue reading Border Collision Bifurcations in a Generalized Model of Population Dynamics
Using avatars to win the fight over BRAF inhibitor resistance
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1XwCWr2 via IFTTT
Initiation and completion rates for latent tuberculosis infection treatment: a systematic review
Control of latent tuberculosis infection (LTBI) is an important step towards tuberculosis elimination. Preventive treatment will prevent the development of disease in most cases diagnosed with LTBI. However, l... from Infection via ola Kala on Inoreader http://ift.tt/24WTCKt via IFTTT
The effect of growth rate on pyrazinamide activity in Mycobacterium tuberculosis - insights for early bactericidal activity?
Pyrazinamide (PZA) plays an essential part in the shortened six-month tuberculosis (TB) treatment course due to its activity against slow-growing and non-replicating organisms. We tested whether PZA preferenti... from Infection via ola Kala on Inoreader http://ift.tt/1XimYjX via IFTTT
Using avatars to win the fight over BRAF inhibitor resistance
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1XwCWr2 via IFTTT
Obstacle Aware Connectivity Restoration for Disjoint Wireless Sensor Networks Using a Mix of Stationary and Mobile Nodes
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
In many applications, wireless sensor networks (WSNs) are deployed in inhospitable environments and therefore the nodes are at increased risk of failure. Large scale damage may partition a network into disjoint segments, which has very negative effect on the application. Mobile nodes have been exploited to act as mobile data collectors (MDCs) among segments to […]
Dissolution of (1-3),(1-4)-β-Glucans in Pressurized Hot Water: Quantitative Assessment of the Degrad ation and the Effective Extraction
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The purpose of this work was to study the behavior of (1-3)(1-4)-β-D-glucan in pressurized hot water. For this purpose, solid β-glucan (450 kDa) was put in water and heated at different temperatures (120, 150, and 170°C) for different times (5 to 360 minutes). At 120°C it was found that the highest soluble β-glucan concentration was measured […]
Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The present study was designed to investigate the cardioprotective effects of Sundarban honey (SH) in rats with isoproterenol- (ISO-) induced myocardial infarction. Adult male Wistar Albino rats were pretreated with Sundarban honey (5 g/kg) daily for a period of 6 weeks. After the treatment period, ISO (85 mg/kg) was subcutaneously injected into the rats at 24 h intervals […]
Effect of Electronic Messaging on Physical Activity Participation among Older Adults
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The purpose of this study was to determine if electronic messaging would increase min of aerobic physical activity (PA) among older adults. Participants were active older adults (; M age = 60 years, SD = 5.99, and range = 51–74 years). Using an incomplete within-subjects crossover design, participants were randomly assigned to begin the 4-week […]
IJERPH, Vol. 13, Pages 506: Contributing Factors to Colorectal Cancer Screening among Chinese People: A Review of Quantitative Studies
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Colorectal cancer (CRC) is a major health problem in Asia. It has been reported that the Chinese are more susceptible to CRC than many other ethnic groups. Screening for CRC is a cost-effective prevention and control strategy; however, the screening rates among the Chinese are sub-optimal. We conducted a review to identify the factors associated […]
IJERPH, Vol. 13, Pages 497: Orange Is the New Green: Exploring the Restorative Capacity of Seasonal Foliage in Schoolyard Trees
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Urban schoolyard environments are increasingly characterized by a proliferation of hard surfaces with little if any greenery. Schoolyard “greening” initiatives are becoming increasingly popular; however, schoolyard designs often fail to realize their restorative potential. In this quasi-experimental study, a proposed schoolyard greening project was used to visualize alternative planting designs and seasonal tree foliage; these […]
Source-specific workplace social support and high-sensitivity C-reactive protein levels among Japanese workers: A 1-year prospective cohort study
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background This study investigated the prospective association between source-specific workplace social support and high-sensitivity C-reactive protein (hs-CRP) levels in workers in Japan. Methods We conducted a 1-year prospective cohort study with 1,487 men and 533 women aged 18–65 years. Participants worked at two manufacturing worksites in Japan and were free of major illness. We used […]
Long-term self-reported exposure to occupational noise is associated with BMI-defined obesity in the US general population
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background Evidence is emerging about the risk of obesity associated with traffic noise. The present study aimed to explore the association between self-reported occupational noise exposure and body mass index (BMI)-defined obesity in the US general population. Methods This study is based on the 2014 National Health Interview Survey. Information regarding self-reported occupational lifetime noise […]
The accuracy of spleen stiffness measurement to predict varices in chronic hepatitis B cirrhotic patients with or without taking non-selective beta-blockers
ABSTRACT Background & Aims The accuracy of liver and spleen stiffness measurement (LSM & SSM) with transient elastography to predict varices in the presence of non-selective beta-blockers (NSBB) has never been studied before. Methods This was a cross-sectional study of consecutive patients with chronic hepatitis B (CHB) and cirrhosis. All patients underwent transient elastography and upper endoscopic examinations. Performance of LSM and SSM to predict varices in patients did and did not receive NSBB was evaluated. Results 144 CHB patients (29 received NSBB; 35 had any varices, 3... περισσότερα »
Adaptive parameter particle CBMeMBer tracker for multiple maneuvering target tracking
Cardinality-balanced multi-target multi-Bernoulli (CBMeMBer) filter has been demonstrated as a promising algorithm for multi-target tracking, and the multi-model (MM) method has been incorporated into the CBMe... from Biomedical Engineering via ola Kala on Inoreader http://ift.tt/1rRfFnz via IFTTT
The accuracy of spleen stiffness measurement to predict varices in chronic hepatitis B cirrhotic patients with or without taking non-selective beta-blockers
ABSTRACT Background & Aims The accuracy of liver and spleen stiffness measurement (LSM & SSM) with transient elastography to predict varices in the presence of non-selective beta-blockers (NSBB) has never been studied before. Methods This was a cross-sectional study of consecutive patients with chronic hepatitis B (CHB) and cirrhosis. All patients underwent transient elastography and upper endoscopic examinations. Performance of LSM and SSM to predict varices in patients did and did not receive NSBB was evaluated. Results 144 CHB patients (29 received NSBB; 35 had any varices, 3... περισσότερα »
Acquired Color Vision Defects and Hexane Exposure: A Study of San Francisco Bay Area Automotive Mechanics
Occupational exposure to solvents, including *n-*hexane, has been associated with acquired color vision defects. Blue-yellow defects are most common and may be due to neurotoxicity or retinal damage. Acetone may potentiate the neurotoxicity of *n-*hexane. We present results on nonhexane solvent and hexane exposure and color vision from a cross-sectional study of 835 automotive repair workers in the San Francisco Bay Area, California (2007–2013). Cumulative exposure was estimated from self-reported work history, and color vision was assessed using the Lanthony desaturated D-15 pane... περισσότερα »
Exposure to Ambient Air Pollution and Premature Rupture of Membranes
Premature rupture of membranes (PROM) is a major factor that predisposes women to preterm delivery. Results from previous studies have suggested that there are associations between exposure to air pollution and preterm birth, but evidence of a relationship with PROM is sparse. Modified Community Multiscale Air Quality models were used to estimate mean exposures to particulate matter less than 10 µm or less than 2.5 µm in aerodynamic diameter, nitrogen oxides, carbon monoxide, sulfur dioxide, and ozone among 223,375 singleton deliveries in the Air Quality and Reproductive Health St... περισσότερα »
Children, youth take longer to fully recover from concussion: York U study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The latest York U concussion research studied the prolonged difficulty in cognitive-motor integration in 50 children and adolescents with a history of concussion. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1TkrDR0 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
GSE70301 Expression data from oral squamous cell carcinoma cell line Cal27 after lentivirus shIL-1beta transfection
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
*Contributor* : Tong Wu *Series Type* : Expression profiling by array *Organism* : Homo sapiens Oral squamous cell carcinoma cell line Cal27 was transfected with lentiviral shIL-1beta or scrambled shRNA. We used microarrays to detail the global program of gene expression during this process. from squamous cell carcinoma via ok on Inoreader http://ift.tt/25av7Nm via IFTTT
System Review about Function Role of ESCC Driver Gene KDM6A by Network Biology Approach
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
Background. KDM6A (Lysine (K)-Specific Demethylase 6A) is the driver gene related to esophageal squamous cell carcinoma (ESCC). In order to provide more biological insights into KDM6A, in this paper, we treat PPI (protein-protein interaction) network derived from KDM6A as a conceptual framework and follow it to review its biological function. Method. We constructed a PPI network with Cytoscape software and performed clustering of network with Clust&See. Then, we evaluate the pathways, which are statistically involved in the network derived from KDM6A. Lastly, gene ontology analysi...περισσότερα »
Outcomes of intensity‐modulated radiotherapy as primary treatment for oropharyngeal squamous cell carcinoma – a European single institution analysis
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
ConclusionsOutcomes with IMRT are favourable, particularly in the HPV‐positive patient group. This data further supports the use of a previously described prognostication model that can be used to select patients for escalation/de‐escalation clinical trials.This article is protected by copyright. All rights reserved. (Source: Clinical Otolaryngology) *MedWorm Sponsor Message:* Directory of the best January Sales in the UK. Find the best Christmas presents too. from squamous cell carcinoma via ok on Inoreader http://ift.tt/27uFmKZ via IFTTT
Role of prophylactic central compartment lymph node dissection in clinically N0 differentiated thyroid cancer patients: analysis of risk factors and review of modern trends
Abstract In the last years, especially thanks to a large diffusion of ultrasound-guided FNBs, a surprising increased incidence of differentiated thyroid cancer (DTC), "small" tumors and microcarcinomas have been reported in the international series. This led endocrinologists and surgeons to search for "tailored" and "less aggressive" therapeutic protocols avoiding risky morbidity and useless "overtreatment". Considering the most recent guidelines of referral endocrine societies, we analyzed the role of routine or so-called prophylactic central compartment lymph node dissection (RCL... περισσότερα »
Role of prophylactic central compartment lymph node dissection in clinically N0 differentiated thyroid cancer patients: analysis of risk factors and review of modern trends
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract In the last years, especially thanks to a large diffusion of ultrasound-guided FNBs, a surprising increased incidence of differentiated thyroid cancer (DTC), “small” tumors and microcarcinomas have been reported in the international series. This led endocrinologists and surgeons to search for “tailored” and “less aggressive” therapeutic protocols avoiding risky morbidity and useless “overtreatment”. Considering […]
Source-specific workplace social support and high-sensitivity C-reactive protein levels among Japanese workers: A 1-year prospective cohort study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background This study investigated the prospective association between source-specific workplace social support and high-sensitivity C-reactive protein (hs-CRP) levels in workers in Japan. Methods We conducted a 1-year prospective cohort study with 1,487 men and 533 women aged 18–65 years. Participants worked at two manufacturing worksites in Japan and were free of major illness. We used […]
Long-term self-reported exposure to occupational noise is associated with BMI-defined obesity in the US general population
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background Evidence is emerging about the risk of obesity associated with traffic noise. The present study aimed to explore the association between self-reported occupational noise exposure and body mass index (BMI)-defined obesity in the US general population. Methods This study is based on the 2014 National Health Interview Survey. Information regarding self-reported occupational lifetime noise […]
Collegium Ramazzini: Comments on the 2014 Helsinki consensus report on asbestos
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1qqkKC7 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Workplace psychosocial and organizational factors for neck pain in workers in the United States
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background Neck pain is a prevalent musculoskeletal condition among workers in the United States. This study explores a set of workplace psychosocial and organization-related factors for neck pain. Methods Data used for this study come from the 2010 National Health Interview Survey which provides a representative sample of the US population. To account for the […]
Mortality from neurodegenerative diseases in a cohort of US flight attendants
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background Concern exists about the potential chronic neurological effects among aircrew of exposure to chemical contaminants from engine oil in aircraft cabin air. We evaluated mortality from neurodegenerative diseases among 11,311 former US flight attendants. Methods Vital status was ascertained through 2007, and life table analyses were conducted to obtain standardized mortality ratios (SMRs). Results […]
Impfung als Anaphylaxie-Trigger
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Seltener Notfall Ärzte, die impfen, müssen auch für den Fall einer anaphylaktischen Reaktion gerüstet sein. Die Maximalform der allergischen Reaktion tritt allerdings extrem selten ein. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/27uVpbI via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
GSE70301 Expression data from oral squamous cell carcinoma cell line Cal27 after lentivirus shIL-1beta transfection
Contributor : Tong Wu Series Type : Expression profiling by array Organism : Homo sapiens Oral squamous cell carcinoma cell line Cal27 was transfected with lentiviral shIL-1beta or scrambled shRNA. We used microarrays to detail the global program of gene expression during this process. from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/25av7Nm via IFTTT
Obstacle Aware Connectivity Restoration for Disjoint Wireless Sensor Networks Using a Mix of Stationary and Mobile Nodes
In many applications, wireless sensor networks (WSNs) are deployed in inhospitable environments and therefore the nodes are at increased risk of failure. Large scale damage may partition a network into disjoint segments, which has very negative effect on the application. Mobile nodes have been exploited to act as mobile data collectors (MDCs) among segments to… Continue reading Obstacle Aware Connectivity Restoration for Disjoint Wireless Sensor Networks Using a Mix of Stationary and Mobile Nodes
Dissolution of (1-3),(1-4)-β-Glucans in Pressurized Hot Water: Quantitative Assessment of the Degrad ation and the Effective Extraction
The purpose of this work was to study the behavior of (1-3)(1-4)-β-D-glucan in pressurized hot water. For this purpose, solid β-glucan (450 kDa) was put in water and heated at different temperatures (120, 150, and 170°C) for different times (5 to 360 minutes). At 120°C it was found that the highest soluble β-glucan concentration was measured… Continue reading Dissolution of (1-3),(1-4)-β-Glucans in Pressurized Hot Water: Quantitative Assessment of the Degrad ation and the Effective Extraction
Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats
The present study was designed to investigate the cardioprotective effects of Sundarban honey (SH) in rats with isoproterenol- (ISO-) induced myocardial infarction. Adult male Wistar Albino rats were pretreated with Sundarban honey (5 g/kg) daily for a period of 6 weeks. After the treatment period, ISO (85 mg/kg) was subcutaneously injected into the rats at 24 h intervals… Continue reading Sundarban Honey Confers Protection against Isoproterenol-Induced Myocardial Infarction in Wistar Rats
Effect of Electronic Messaging on Physical Activity Participation among Older Adults
The purpose of this study was to determine if electronic messaging would increase min of aerobic physical activity (PA) among older adults. Participants were active older adults (; M age = 60 years, SD = 5.99, and range = 51–74 years). Using an incomplete within-subjects crossover design, participants were randomly assigned to begin the 4-week… Continue reading Effect of Electronic Messaging on Physical Activity Participation among Older Adults
Role of prophylactic central compartment lymph node dissection in clinically N0 differentiated thyroid cancer patients: analysis of risk factors and review of modern trends
Abstract In the last years, especially thanks to a large diffusion of ultrasound-guided FNBs, a surprising increased incidence of differentiated thyroid cancer (DTC), “small” tumors and microcarcinomas have been reported in the international series. This led endocrinologists and surgeons to search for “tailored” and “less aggressive” therapeutic protocols avoiding risky morbidity and useless “overtreatment”. Considering… Continue reading Role of prophylactic central compartment lymph node dissection in clinically N0 differentiated thyroid cancer patients: analysis of risk factors and... περισσότερα »
Impfung als Anaphylaxie-Trigger
Seltener Notfall Ärzte, die impfen, müssen auch für den Fall einer anaphylaktischen Reaktion gerüstet sein. Die Maximalform der allergischen Reaktion tritt allerdings extrem selten ein. from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/27uVpbI via IFTTT
Role of prophylactic central compartment lymph node dissection in clinically N0 differentiated thyroid cancer patients: analysis of risk factors and review of modern trends
Abstract In the last years, especially thanks to a large diffusion of ultrasound-guided FNBs, a surprising increased incidence of differentiated thyroid cancer (DTC), "small" tumors and microcarcinomas have been reported in the international series. This led endocrinologists and surgeons to search for "tailored" and "less aggressive" therapeutic protocols avoiding risky morbidity and useless "overtreatment". Considering the most recent guidelines of referral endocrine societies, we analyzed the role of routine or so-called prophylactic central compartment lymph node dissection (RCL... περισσότερα »
The Role of Curvature on Diels-Alder Functionalization of Carbon-Based Materials: A Unified Picture
[image: CrossMark.jpg] [image: CrossMark.jpg] *Chem. Commun.*, 2016, Accepted Manuscript *DOI*: 10.1039/C6CC01427E, Communication Bertrand Willocq, Vincent Lemaur, Mohamed El Garah, Artur Ciesielski, Paolo Samori, Jean-Marie Raquez, Philippe Dubois, Jerome Cornil We have estimated theoretically the impact of curvature on the free enthalpies of activation and reaction associated to Diels-Alder reactions on carbon-based materials. Significant reductions are calculated for both energy... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 ... περισσότερα »
Versatile theranostics agents designed by coating ferrite nanoparticles with biocompatible polymers
Three biocompatible polymers, polyethylene glycol (PEG), dextran and chitosan, have been used in this work to control the colloidal stability of magnetic nanoparticles (14 ± 5 nm in diameter) and to vary the aggregation state in order to study their effect on relaxometric and heating properties. Two different coating strategies have been deeply developed; one based on the formation of an amide bond between citric acid coated nanoparticles (NPs) and amine groups present on the polymer surface and the other based on the NP encapsulation. Relaxometric properties revealed that proton ... περισσότερα »
Mortality in HIV-infected patients with tuberculosis treated with streptomycin and a two-week intensified regimen: data from an HIV cohort study using inverse probability of treatment weighting
[image: fig-1-1x.jpg] Background. Despite the dramatic scale-up of antiretroviral therapy in low- and middle-income countries, tuberculosis (TB) is still the main cause of death among HIV-infected patients in resource-limited settings. Previous studies in patients with TB meningitis suggest that the use of higher doses of common anti-TB drugs could reduce mortality. Methods. Using clinical data from an HIV cohort study in India, we compared the mortality among HIV-infected patients diagnosed with TB according to the regimen received during the first two weeks of treatment: standard...περισσότερα »
Yet another new species from one of the best-studied neotropical areas: Plantago humboldtiana (Plantaginaceae), an extremely narrow endemic new species from a waterfall in southern Brazil
[image: fig-1-1x.jpg] This article presents and describes Plantago humboldtiana, an extremely narrow endemic rheophytic new species from a waterfall in Corupá, Santa Catarina state, southern Brazil. The new species is unique in presenting a combination of type-G antrorse trichomes on scapes, pendulous inflorescences and 1-seeded pyxidia. Only one population is known to exist, despite intensive search effort in nearby, similar environments. Its conservation status is assessed as critically endangered (CR) as the only known population is restricted to a dramatically small area, and i... περισσότερα »
A biofilter for treating toluene vapors: performance evaluation and microbial counts behavior
[image: fig-1-1x.jpg] A lab-scale biofilter packed with mixed packing materials was used for degradation of the toluene. Different empty bed residence times, 148.3, 74.2 and 49.4 s, were tested for inlet concentration ranging from 0.2 to 1.2 g/m3. The maximum elimination capacity of 36.0 g/(m3 h) occurred at an inlet loading rate of 45.9 g/(m3 h). The contribution of the lower layer was higher than other layers and always had the highest elimination capacity. The carbon dioxide production rate and distribution of micro-organisms followed toluene elimination capacities. The results ... περισσότερα »
Macromol. Rapid Commun. 10/2016
[image: Thumbnail image of graphical abstract] *Back Cover:* Sustainable polyamides with side groups and stereocenters are synthesized starting from L-menthone. This terpenoid ketone is transformed in a one-step synthesis into a chiral lactam, which is then polymerized via ring-opening polymerization (ROP). The beneficial properties of these polymers are thus introduced via the structure and chirality of the lactam monomer. Further details can be found in the article by M. Winnacker*, M. Neumeier, X. Zhang, C. M. Papadakis, and B. Rieger on page 851. from Biomedical Engineering vi...περισσότερα »
Characterization of a computed radiography system for external radiotherapy beam dosimetry
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
A commercial computed radiography (CR) system was studied as an option for quantitative dosimetry quality assurance of external radiotherapy beams. Following the examination of influencing quantities, practical measurement procedures are discussed. Corrections were derived for image fading, an observed long-term response drift and the image length scale, which was found to be off by up […]
Hybrid x-space: a new approach for MPI reconstruction
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Magnetic particle imaging (MPI) is a new medical imaging technique capable of recovering the distribution of superparamagnetic particles from their measured induced signals. In literature there are two main MPI reconstruction techniques: measurement-based (MB) and x-space (XS). The MB method is expensive because it requires a long calibration procedure as well as a reconstruction phase […]
Antioxidants, Vol. 5, Pages 15: Antioxidant Cerium Oxide Nanoparticles in Biology and Medicine
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Previously, catalytic cerium oxide nanoparticles (CNPs, nanoceria, CeO2-x NPs) have been widely utilized for chemical mechanical planarization in the semiconductor industry and for reducing harmful emissions and improving fuel combustion efficiency in the automobile industry. Researchers are now harnessing the catalytic repertoire of CNPs to develop potential new treatment modalities for both oxidative- and nitrosative-stress […]
Magic-mushroom drug lifts depression in first human trial
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Researchers’ long fight to test psilocybin’s safety finally yields fruit. Nature News doi: 10.1038/nature.2016.19919 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1slXIO0 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Publication date: Available online 17 May 2016 Source:Molecular Oncology Author(s): Mariana Lagadari, Nadia R. Zgajnar, Luciana I. Gallo, Mario D. Galigniana FK506-binding proteins are members of the immunophilin family of proteins. Those immunophilins associated to the 90-kDa-heat-shock protein, Hsp90, have been proposed as potential modulators of signalling cascade factors chaperoned by Hsp90. FKBP51 and FKBP52 […]
Exposure-response relationships between movements and postures of the wrist and carpal tunnel syndrome among male and female house painters: a retrospective cohort study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Objectives To investigate exposure–response relationships between measured movements and postures of the wrist and the incidence of carpal tunnel syndrome (CTS), and any modifications by sex. Methods In 2011, we established a historical cohort of 9364 members of the Painters’ Union in Denmark. Self-reported task distributions were obtained by questionnaire (53% responded) and combined with […]
The crucial role of FBXO28 in the pathogenesis of the 1q41q42 microdeletion syndrome
from Genetics via xlomafota13 on Inoreader http://ift.tt/1TkWwDJ via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1XwjMS4 via IFTTT
Coming of age: ten years of next-generation sequencing technologies
Nature Reviews Genetics 17, 333 (2016). doi:10.1038/nrg.2016.49 Authors: Sara Goodwin, John D. McPherson & W. Richard McCombie Since the completion of the human genome project in 2003, extraordinary progress has been made in genome sequencing technologies, which has led to a decreased cost per megabase and an increase in the number and diversity of sequenced genomes. An astonishing complexity of genome architecture [image: 1TFNBdd] from Genetics via xlomafota13 on Inoreader http://ift.tt/1TdDKRJ via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on ... περισσότερα »
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