Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients – News-Medical.net
TV3.ie Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients News-Medical.net Researchers at the University of Cincinnati (UC) College of Medicine have found that adding increasing doses of an approved Type 2 diabetes drug, metformin, to a chemotherapy and radiation treatment regimen in head and neck cancer patients is not well …… Continue reading Metformin along with chemotherapy/radiation improves outcomes in head and neck cancer patients – News-Medical.net
Optimal Stable Approximation for the Cauchy Problem for Laplace Equation
Cauchy problem for Laplace equation in a strip is considered. The optimal error bounds between the exact solution and its regularized approximation are given, which depend on the noise level either in a Hölder continuous way or in a logarithmic continuous way. We also provide two special regularization methods, that is, the generalized Tikhonov regularization… Continue reading Optimal Stable Approximation for the Cauchy Problem for Laplace Equation
Transport and dispersal of Stictococcus vayssierei (Homoptera, Stictococcidae) by Anoplolepis tenella (Hymenoptera, Formicidae)
Dispersal can be a crucial factor affecting fitness in insects. We conducted a series of experiments and observations with the aim of determining the dispersal mode of the African root and tuber scale Stictococcus vayssierei, a pest on cassava in the Congo Basin. We monitored the main options of dispersal that occurred in scale insects:… Continue reading Transport and dispersal of Stictococcus vayssierei (Homoptera, Stictococcidae) by Anoplolepis tenella (Hymenoptera, Formicidae)
Boric acid for the suppression of the ant Anoplolepis tenella and effects on an associated scale insect pest Stictococcus vayssierei in cassava fields in the Congo Basin
The scale insect, Stictococcus vayssierei, is one of the major pests and constraints to cassava production in the Congo Basin. It is frequently found associated with the ground nesting ant, Anoplolepis tenella, under cassava plant. Amdro fire ant bait granules (contains 7.3 g/kg Hydramethylnon), borax and boric acid solution were evaluated in the laboratory for… Continue reading Boric acid for the suppression of the ant Anoplolepis tenella and effects on an associated scale insect pest Stictococcus vayssierei in cassava fields in the Congo Basin
Copper sulphate reduces the metabolic activity of Gammarus fossarum in laboratory and field experiments
The specialised fauna of freshwater springs is affected by contamination of the water with xenobiotics from human activities in the surrounding landscape. We assessed the effects of exposure to toxins in laboratory and field experiments by using copper sulphate as a model substance and Gammarus fossarum Koch, 1836, as the model organism. This amphipod is… Continue reading Copper sulphate reduces the metabolic activity of Gammarus fossarum in laboratory and field experiments
Effects of increased temperatures on Gammarus fossarum under the influence of copper sulphate
The specialised fauna of freshwater springs will have to cope with a possible temperature rise owing to Global Change. It is affected additionally by contamination of the water with xenobiotics from human activities in the surrounding landscape. We assessed the combined effects of temperature increase and exposure to toxins in laboratory experiments by using copper… Continue reading Effects of increased temperatures on Gammarus fossarum under the influence of copper sulphate
Temperature effects on the feeding and electron transport system (ETS) activity of Gammarus fossarum
The effects of an increase in water temperature as a direct consequence of global change on organisms living in springs and spring brooks have rarely been studied in laboratory experiments. In this study, experiments were conducted to test the response of Gammarus fossarum Koch, 1836, as an abundant representative of the European spring fauna, to… Continue reading Temperature effects on the feeding and electron transport system (ETS) activity of Gammarus fossarum
Macroinvertebrate assemblages of natural springs along an altitudinal gradient in the Bernese Alps, Switzerland
Alpine springs are sensitive ecotones which are inhabited by highly adapted organisms. Studies on how the species assemblages change vertically have not been conducted previously. We investigated 35 natural springs along an altitudinal gradient of about 2000 m in a valley in the Bernese Alps over 2 years. The aim of this study was to… Continue reading Macroinvertebrate assemblages of natural springs along an altitudinal gradient in the Bernese Alps, Switzerland
Taxes in Cities
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1X6BDQh via IFTTT
Schutzwürdigkeit des Embryos: Allgemeine Begründungen und die Konzeption im Entwurf zum Embryo nenforschungsgesetz
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1Zr3nNE via IFTTT
Education and Training in Hemostasis
Education and Training in Hemostasis: [image: gr1.sml] Hemorrhagic emergencies in otolaryngology can present significant challenges to the early practitioner. The development of procedural skills, clinical decision making, effective communication strategies, and leadership remain critical to ensuring positive patient outcomes. Procedural task trainers and simulation-based complex scenarios provide safe and effective learning environments for young practitioners to build confidence and develop such skills. This article reviews the principles of managing epistaxis and postoperati... περισσότερα »
Endoscopic Management of Vascular Sinonasal Tumors, Including Angiofibroma
Endoscopic Management of Vascular Sinonasal Tumors, Including Angiofibroma: [image: gr1.sml] The greatest challenge in the surgical treatment of angiofibromas is dealing with the hypervascularity of these tumors. Staging systems that take into account the vascularity of the tumor may be more prognostic. A variety of treatment strategies are used to deal with the vascularity of angiofibromas, including preoperative embolization, segmentation of the tumor into vascular territories, use of hemostatic tools, and staging of surgery. Even large angiofibromas with intracranial extension a... περισσότερα »
Hemostasis in Orbital Surgery
Hemostasis in Orbital Surgery: [image: gr1.sml] This article highlights the major vascular supply of the orbit and structures supplied by these vessels. Key anatomic principles are then reviewed as they pertain to endoscopic orbital surgery in order to avoid serious orbital hemorrhages. Next, preoperative planning and patient education are outlined as well as description of orbital compartment syndrome. This is followed by discussion of various techniques for managing orbital hemorrhage in the intraoperative and postoperative setting. [image: First page of article]
Managing Vascular Tumors—Open Approaches
Managing Vascular Tumors—Open Approaches: [image: gr1.sml] The most common vascular tumors encountered by the otolaryngologist are rare chromaffin cell tumors termed paragangliomas. Within the head and neck region, they commonly arise from the carotid body, vagus nerve (glomus vagale), and jugular vein (glomus jugulare). Other vascular head and neck tumors include sinonasal malignancies, because of proximity to or involvement of the pterygoid plexus as well as the rich vascularity of the sinonasal mucosa; juvenile nasopharyngeal angiofibroma, a vascular tumor of male adolescent... περισσότερα »
Simulation Training for Vascular Emergencies in Endoscopic Sinus and Skull Base Surgery
Simulation Training for Vascular Emergencies in Endoscopic Sinus and Skull Base Surgery: [image: gr1.sml] Carotid artery injury during endonasal surgery is a feared and potentially catastrophic complication. Simulation training provides the opportunity for a realistic experience with management of major vascular injuries. The sheep model of carotid artery injury reproduces the challenges of dealing with vascular emergencies during endoscopic sinus and skull base surgery, which include working in narrow nasal confines, high-flow/high-pressure vascular injury, and the immediately... περισσότερα »
Hemostatic Options for Transoral Robotic Surgery of the Pharynx and Base of Tongue
Hemostatic Options for Transoral Robotic Surgery of the Pharynx and Base of Tongue: [image: gr1.sml] Surgery with transoral robotic surgery (TORS) offers significant advantages compared with traditional open surgical approaches and potentially minimizes the long-term side effects of organ preservation therapy with chemoradiation. Angled telescopes and wristed instruments allow visualization and access to areas of the pharynx that are difficult to reach with line-of-sight instrumentation. Although the application of TORS in head and neck surgery has expanded considerably, there ... περισσότερα »
Surgical Adhesives in Facial Plastic Surgery
Surgical Adhesives in Facial Plastic Surgery: [image: gr1.sml] In facial plastic surgery, attaining hemostasis may require adjuncts to traditional surgical techniques. Fibrin tissue adhesives have broad applications in surgery and are particularly useful when addressing the soft tissue encountered in facial plastic surgery. Beyond hemostasis, tissue adhesion and enhanced wound healing are reported benefits associated with a decrease in operating time, necessity for drains and pressure dressings, and incidence of wound healing complications. These products are clinically accessi... περισσότερα »
Management of Major Vascular Injury During Endoscopic Endonasal Skull Base Surgery
Management of Major Vascular Injury During Endoscopic Endonasal Skull Base Surgery: [image: gr1.sml] A major vascular injury is the most feared complication of endoscopic sinus and skull base surgery. Risk factors for vascular injury are discussed, and an algorithm for management of a major vascular injury is presented. A team of surgeons (otolaryngology and neurosurgery) is important for identification and control of a major vascular injury applying basic principles of vascular control. A variety of techniques can be used to control a major injury, including coagulation, a mus... περισσότερα »
Treatment of Hereditary Hemorrhagic Telangiectasia–Related Epistaxis
Treatment of Hereditary Hemorrhagic Telangiectasia–Related Epistaxis: [image: gr1.sml] Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease with an incidence of 1:5000. Recurrent, spontaneous epistaxis is the most common presenting symptom. Severity of epistaxis varies widely, from mild, self-limited nosebleeds to severe, life-threatening nasal hemorrhage. Treatment of HHT-related epistaxis presents a challenge to the otolaryngologist due to the recurrent, persistent nature of epistaxis often requiring multiple treatments. Treatment modalities range from ... περισσότερα »
Anesthetic Techniques in Endoscopic Sinus and Skull Base Surgery
Anesthetic Techniques in Endoscopic Sinus and Skull Base Surgery: [image: main.pdf.png] Endoscopic sinus approach has become one of the most common surgical techniques for endoscopic sinus and skull base surgery. Anesthetic management has an important impact on the overall patient management, from the preoperative assessment and management to the quality of the surgical field and the postoperative recovery. Hemostasis is critical for adequate anatomical endoscopic visualization. Mild controlled hypotension seems to improve the visibility of the surgical field. Reduction of intra... περισσότερα »
Thyroidectomy Hemostasis
Thyroidectomy Hemostasis: [image: gr1.sml] Total thyroidectomy has significantly changed over the years from a morbid procedure to one that is performed routinely on an outpatient basis. This article reviews the history of thyroid surgery with regard to hemostasis, discusses surgical vascular anatomy, and describes the methods of hemostasis. It compares traditional hemostatic surgical techniques with newer techniques such as the Harmonic Scalpel and LigaSure hand pieces. The use of adjunctive hemostatic agents and indications for a drain in thyroid are discussed. [image: Firs... περισσότερα »
Hemostasis in Tonsillectomy
Hemostasis in Tonsillectomy: [image: gr1.sml] Tonsillectomy is a commonly performed procedure with an accepted risk of posttonsillectomy hemorrhage (PTH) approaching 5%, but catastrophic effects of hemorrhage are exceedingly rare. A variety of surgical techniques and hemostatic agents have been used to reduce the rate of hemorrhage, although none eliminate the risk. Numerous patient, surgical, and postoperative care factors have been studied for an association with PTH. The most consistent risk factors for PTH seem to be patient age and coagulopathies. Surgeon skill and surgica... περισσότερα »
Hemostasis in Otologic and Neurotologic Surgery
Hemostasis in Otologic and Neurotologic Surgery: [image: gr1.sml] Hemostasis is a critical component of otologic and neurotologic surgery. In these surgeries the surgical field is small; thus, even a small amount of bleeding can obstruct the view of critical and extremely small structures. Additionally, relatively large vascular structures traverse the area; if they are encroached on by trauma or disease, bleeding must be controlled within a very small space in a meticulous fashion that does not encroach on structures of the middle ear and mastoid. The authors discuss several hemo... περισσότερα »
Hemostasis in Pediatric Surgery
Hemostasis in Pediatric Surgery: [image: main.pdf.png] Hemostasis is an important concept in pediatric otolaryngologic surgery. This article details the considerations the otolaryngologist should take when it comes to clinical evaluation and surgical technique. It begins with the preoperative evaluation, and evolves into the use of different mechanical and chemical methods of operative hemostasis. We detail use of different hemostatic techniques in common pediatric procedures, and finally, we discuss indications for intraoperative and postoperative blood transfusion in pediatri... περισσότερα »
Hemostasis in Endoscopic Sinus Surgery
Hemostasis in Endoscopic Sinus Surgery: [image: main.pdf.png] Intraoperative bleeding during endoscopic sinus surgery poses an additional dimension to an already technically challenging surgical approach because of the narrow sinonasal surgical field, single working hand, and the use of endoscopic instruments. Poor visualization is one of the most important factors that increase the risk of intraoperative complications such as inadvertent injury to major vessels and nerves, and incomplete surgery. This article provide a logical approach to improving the surgical field, minimizi... περισσότερα »
Hemostasis in Laryngeal Surgery
Hemostasis in Laryngeal Surgery: [image: gr1.sml] The larynx is a highly vascularized organ supplied by the superior and inferior laryngeal arteries. Both microphonosurgery and external laryngeal surgery require excellent hemostasis. Topical agents including adrenalin and fibrin-based products as well as surgical instrumentation, such as coagulation devices or in some cases embolization, are in the surgeon’s armamentarium and facilitate efficient and successful surgery. [image: First page of article]
Endovascular Management of Diseases in Relation to Otolaryngology
Endovascular Management of Diseases in Relation to Otolaryngology: [image: gr1.sml] Endovascular techniques can be utilized in many common otolaryngologic conditions. Advancements in in these techniques including but not limited to better distal access catheters, new embolization materials and stents allows this to be a relatively safe and successful procedure. Here we highlighted a few related procedures. [image: First page of article]
Endoscopic endonasal access for the treatment of Vidian nerve schwannoma
: a case report via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Introduction Schwannomas are benign tumors of Schwann cells of the nerve sheath and constitute 8% of intracranial primary neoplasms. The most common origin is the vestibular nerve1 located in the cerebellopontine angle, corresponding to 51% of all tumors of the nerve sheath. The second most frequent type of schwannoma has its origin in the trigeminal nerve and may represent 8% of all schwannomas. Vidian nerve schwannomas are extremely rare lesions and only seven cases have been reported in the lit... περισσότερα »
Nasal liquorrhea
Endoscopic repair of cerebrospinal fluid fistulas in via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online June 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Vladimir Kljajić, Petar Vuleković, Ljiljana Vlaški, Slobodan Savović, Danijela Dragičević, Vladimir Papić IntroductionNasal liquorrhea indicates a cerebrospinal fluid fistula, an open communication between the intracranial cerebrospinal fluid and the nasal cavity. It can be traumatic and spontaneous.ObjectiveThe aim of this study was to assess the outcome of... περισσότερα »
Pediatric lymphedema caused by diffuse cervical lymphadenopathy
: A case report and review of the literature via International Journal of Pediatric Otorhinolaryngology Publication date: August 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 87 Author(s): Sarah A. Gitomer, Carla M. Giannoni, Karina T. Cañadas Pediatric head and neck lymphedema is rare and there have not been any reported cases in children. Here we discuss severe, diffuse head and neck lymphedema in a child caused by compression of the internal jugular veins by lymphadenopathy from Kawasaki's disease. With steroid and intravenous immunoglobulin treatment,... περισσότερα »
Association of Betel Nut with Carcinogenesis
Revisit with a Clinical Perspective: by Rajeshwar N. Sharan, Ravi Mehrotra, Yashmin Choudhury, Kamlesh Asotra Abstract Betel nut (BN), betel quid (BQ) and products derived from them are widely used as a socially endorsed masticatory product. The addictive nature of BN/BQ has resulted in its widespread usage making it the fourth most abused substance by humans. Progressively, several additives, including chewing tobacco, got added to simple BN preparations. This addictive practice has been shown to have strong etiological correlation with human susceptibility to cancer, particula... περισσότερα »
Neonatal cleft lip repair
Treatment outcome after neonatal cleft lip repair in 5-year-old children with unilateral cleft lip and palate via International Journal of Pediatric Otorhinolaryngology Publication date: August 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 87 Author(s): Olga Košková, Jitka Vokurková, Jan Vokurka, Alena Bryšova, Pavel Šenovský, Julie Čefelínová, Darina Lukášová, Petra Dorociaková, Juraj Abelovský IntroductionThe aim of this study was to assess speech outcomes and dental arch relationship of 5-year-old Czech patients with unilateral cleft lip and palate (U... περισσότερα »
Prognostic value of posttreatment neutrophil–lymphocyte ratio
in head and neck squamous cell carcinoma treated by chemoradiotherapy via Auris Nasus Larynx Publication date: Available online June 2016 *Source:*Auris Nasus Larynx Author(s): Do Young Kim, In Su Kim, Sang Gyu Park, Hyojeong Kim, Young Jin Choi, Young Mi Seol ObjectiveAn inflammatory-immunological marker, C-reactive protein (CRP), neutrophil-to-lymphocyte ratio (NLR), was evaluated as a predictive marker of advanced head and neck cancer patients receiving chemoradiotherapy.MethodsThis study included 104 patients with treatment-naïve head and neck cancer who underwent definitive che... περισσότερα »
Botulinum toxin for the treatment of trigeminal and postherpetic neuralgia
The efficacy of botulinum toxin for the treatment of trigeminal and postherpetic neuralgia: a systematic review with meta-analyses.: Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Jul;122(1):61-71 Authors: Shackleton T, Ram S, Black M, Ryder J, Clark GT, Enciso R Abstract OBJECTIVE: To evaluate the efficacy of a botulinum toxin type A (BoTN-A) in treating trigeminal neuralgia (TN) and postherpetic neuralgia (PHN). STUDY DESIGN: Three databases were searched: Medline, Web of Science, and Cochrane Library. The search was restricted to English-language randomized, placebo-controlled... περισσότερα »
Oral lichen planus is a noninfectious, chronic inflammatory condition that involves the oral mucosal stratified squamous epithelium and the underlying lamina propria and may be accompanied by skin lesions
Etiology and pathogenesis of oral lichen planus: an overview.: Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Jul;122(1):72-80 Authors: Kurago ZB Abstract Oral lichen planus is a noninfectious, chronic inflammatory condition that involves the oral mucosal stratified squamous epithelium and the underlying lamina propria and may be accompanied by skin lesions. This overview describes the current understanding of the immunopathologic mechanisms implicated in oral lichen planus. PMID: 27260276 [PubMed - in process]
The Reliability of Oral and Pharyngeal Dimensions Captured with Acoustic Pharyngometry.
*The Reliability of Oral and Pharyngeal Dimensions Captured with Acoustic Pharyngometry.* Dysphagia. 2016 Jun 4; Authors: Molfenter SM Abstract Acoustic Pharyngometry (APh) is a method for quantifying oropharyngeal tract configuration using sound wave reflection and is commonly used in diagnostics and research of sleep apnea. The standard preset output of APh (minimal cross-sectional area) has been established as reliable. However, by conducting post-processing measures on specific breathing tasks, APh data can also reveal oral length, oral volume, pharyngeal length, and pharyng... περισσότερα »
Transposition of lingual thyroid gland to the submandibular region by transoral approach.
*Transposition of lingual thyroid gland to the submandibular region by transoral approach.* Auris Nasus Larynx. 2016 Jun 1; Authors: Akbay E, Simsek G, Kilic R Abstract The purpose of this case report is to demonstrate surgical technique of only functional but symptomatic lingual thyroid gland transposition to submandibular region by transoral approach without mandibulotomy and tongue-splitting. A 37-year-old female patient was admitted to our hospital with dysphagia and apnea symptoms. Physical examination revealed 3cm×3cm lingual thyroid gland was detected at the tongue base. T... περισσότερα »
Quality of life of type 2 diabetes patients in a tertiary care hospital in southern part of India, Shimoga, Karnataka: a cross-sectional study
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
2016-06-06T04-30-34Z *Source:* International Journal of Community Medicine and Public Health Santosh Kumar A, Raghavendraswamy Koppad, Chandrashekar SV, Revathy. Background: Diabetes mellitus is a non-communicable disease which has reached epidemic proportions. According to World Health Organization (WHO) there is an apparent epidemic of diabetes, which is strongly related to lifestyle and economic change. Objective of the study was to measure the quality of life (QOL) of diabetic patients and to study the various factors influencing the QOL of diabetic patients. Methods: A hospital ... περισσότερα »
Surgical intervention during a Can't Intubate Can't Oxygenate (CICO) event: Emergency Front-of-neck Airway (FONA)?
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Surgical intervention during a Can't Intubate Can't Oxygenate (CICO) event: Emergency Front-of-neck Airway (FONA)?* Clin Otolaryngol. 2016 May 30; Authors: Pracy JP, Brennan L, Cook TM, Hartle AJ, Marks RJ, McGrath BA, Narula A, Patel A PMID: 27241316 [PubMed - as supplied by publisher] from Anaesthesiology via xlomafota13 on Inoreader http://ift.tt/1U93IEC via IFTTT
Obstetric Anaesthetists' Association and Difficult Airway Society guidelines for the management of difficult and failed tracheal intubation in obstetrics.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Obstetric Anaesthetists' Association and Difficult Airway Society guidelines for the management of difficult and failed tracheal intubation in obstetrics.* Anaesthesia. 2015 Nov;70(11):1286-306 Authors: Mushambi MC, Kinsella SM, Popat M, Swales H, Ramaswamy KK, Winton AL, Quinn AC, Obstetric Anaesthetists' Association, Difficult Airway Society Abstract The Obstetric Anaesthetists' Association and Difficult Airway Society have developed the first national obstetric guidelines ... περισσότερα »
Indications and results of emergency surgical airways performed by a physician-staffed helicopter emergency service.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Indications and results of emergency surgical airways performed by a physician-staffed helicopter emergency service.* Injury. 2015 May;46(5):787-90 Authors: Peters J, Bruijstens L, van der Ploeg J, Tan E, Hoogerwerf N, Edwards M Abstract BACKGROUND: Airway management is essential in critically ill or injured patients. In a "can't intubate, can't oxygenate" scenario, an emergency surgical airway (ESA), similar to a cricothyroidotomy, is the final step in airway management. This procedure is infrequently performed ... περισσότερα »
The 'Can't intubate can't oxygenate' scenario in pediatric anesthesia: a comparison of the Melker cricothyroidotomy kit with a scalpel bougie technique.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *The 'Can't intubate can't oxygenate' scenario in pediatric anesthesia: a comparison of the Melker cricothyroidotomy kit with a scalpel bougie technique.* Paediatr Anaesth. 2015 Apr;25(4):400-4 Authors: Prunty SL, Aranda-Palacios A, Heard AM, Chapman G, Ramgolam A, Hegarty M, Vijayasekaran S, von Ungern-Sternberg BS Abstract BACKGROUND: While the majority of pediatric intubations are uncomplicated, the 'Can't intubate, Can't Oxygenate' scenario (CICO) does occur. With limited management guidelines available, CICO ... περισσότερα »
Cricothyrotomy performed with the Melker™ set or the QuickTrach™ kit: procedure times, learning curves and operators' preference.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
[image: http:--http://ift.tt/1Qf2q4n] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Cricothyrotomy performed with the Melker™ set or the QuickTrach™ kit: procedure times, learning curves and operators' preference.* G Chir. 2014 Jul-Aug;35(7-8):165-70 Authors: Buonopane CE, Pasta V, Sottile D, Del Vecchio L, Maturo A, Merola R, Panunzi A, Urciuoli P, D'Orazi V Abstract BACKGROUND: Cricothyroidotomy is a surgical airway technique in which an airway device is inserted into the trachea through an incision made at the cricothyroid membrane. It is used for the management of t... περισσότερα »
Percutaneous transtracheal ventilation in an obstructed airway model in post-apnoeic sheep.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Percutaneous transtracheal ventilation in an obstructed airway model in post-apnoeic sheep.* Br J Anaesth. 2014 Dec;113(6):1039-45 Authors: Berry M, Tzeng Y, Marsland C Abstract BACKGROUND: Temporizing oxygenation by percutaneous transtracheal ventilation (PTV) is a recommended emergency technique in 'can't intubate, can't oxygenate' (CICO) situations. Barotrauma risk increases if expiration is obstructed. The Ventrain(®) is a new PTV device that assists expiration. Our aim was to compare key physiological outcom... περισσότερα »
The effects of a displayed cognitive aid on non-technical skills in a simulated 'can't intubate, can't oxygenate' crisis.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-18-Wi] Related Articles *The effects of a displayed cognitive aid on non-technical skills in a simulated 'can't intubate, can't oxygenate' crisis.* Anaesthesia. 2014 Jul;69(7):669-77 Authors: Marshall SD, Mehra R Abstract Guidelines outlining recommended actions are difficult to implement in the stressful, time-pressured situation of an airway emergency. Cognitive aids such as posters and algorithms improve performance during some anaesthetic emergencies; however, their effects on team behaviours have not been determined. In this study, ... περισσότερα »
Low-cost high-fidelity anaesthetic simulation.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
Related Articles *Low-cost high-fidelity anaesthetic simulation.* Anaesth Intensive Care. 2014 May;42(3):371-7 Authors: Hartwell DA, Grayling M, Kennedy RR Abstract Simulation has been advocated as a useful training tool, and specific manikin simulators have been developed for use in this role. Debriefing and repetition have been identified as key to achieving educational goals and, while the technical features of manikin simulators can influence simulation outcomes, their cost and infrastructure requirements reduce their suitability for smaller healthcare facilities. We describe... περισσότερα »
The effect of high-fidelity simulation on the confidence and decision-making ability of anaesthesia trainees in managing subsequent simulated 'can't intubate, can't oxygenate' scenarios.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
Related Articles *The effect of high-fidelity simulation on the confidence and decision-making ability of anaesthesia trainees in managing subsequent simulated 'can't intubate, can't oxygenate' scenarios.* Anaesth Intensive Care. 2014 Mar;42(2):207-12 Authors: McCrossin K, White HT, Sane S Abstract The decision to attempt a percutaneous airway in a recognised 'Can't Intubate, Can't Oxygenate' (CICO) situation may occur too late to avoid a poor outcome. Our study was designed to investigate the effect of high-fidelity simulation on the confidence and decision-making ability of an... περισσότερα »
Failed intubation and failed oxygenation in a child.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
Related Articles *Failed intubation and failed oxygenation in a child.* Anaesth Intensive Care. 2012 Nov;40(6):1056-8 Authors: Santoro AS, Cooper MG, Cheng A Abstract A 'can't intubate, can't oxygenate' scenario in a child is fortunately extremely rare. We report a case of this life-threatening event in a four-year-old boy suffering from a rare genetic disorder, fibrodysplasia ossificans progressiva. He presented for manipulation of his dislocated jaw and was identified preoperatively as having a difficult airway. Despite extensive preparation, a catastrophic loss of airway contr... περισσότερα »
The 'Can't Intubate Can't Oxygenate' scenario in Pediatric Anesthesia: a comparison of different devices for needle cricothyroidotomy.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *The 'Can't Intubate Can't Oxygenate' scenario in Pediatric Anesthesia: a comparison of different devices for needle cricothyroidotomy.* Paediatr Anaesth. 2012 Dec;22(12):1155-8 Authors: Stacey J, Heard AM, Chapman G, Wallace CJ, Hegarty M, Vijayasekaran S, von Ungern-Sternberg BS Abstract BACKGROUND: Little evidence exists to guide the management of the 'Can't Intubate, Can't Oxygenate' (CICO) scenario in pediatric anesthesia. OBJECTIVES: To compare two intravenous cannulae for ease of use, success rate and compli... περισσότερα »
Likelihood of experiencing 'can't intubate, can't oxygenate'.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 16 δευτερόλεπτα
Related Articles *Likelihood of experiencing 'can't intubate, can't oxygenate'.* Anaesth Intensive Care. 2012 Jul;40(4):722-3 Authors: Riley DP PMID: 22813508 [PubMed - indexed for MEDLINE] from Anaesthesiology via xlomafota13 on Inoreader http://ift.tt/25H449k via IFTTT
The Reliability of Oral and Pharyngeal Dimensions Captured with Acoustic Pharyngometry.
*The Reliability of Oral and Pharyngeal Dimensions Captured with Acoustic Pharyngometry.* Dysphagia. 2016 Jun 4; Authors: Molfenter SM Abstract Acoustic Pharyngometry (APh) is a method for quantifying oropharyngeal tract configuration using sound wave reflection and is commonly used in diagnostics and research of sleep apnea. The standard preset output of APh (minimal cross-sectional area) has been established as reliable. However, by conducting post-processing measures on specific breathing tasks, APh data can also reveal oral length, oral volume, pharyngeal length, and pharyng... περισσότερα »
Transposition of lingual thyroid gland to the submandibular region by transoral approach.
*Transposition of lingual thyroid gland to the submandibular region by transoral approach.* Auris Nasus Larynx. 2016 Jun 1; Authors: Akbay E, Simsek G, Kilic R Abstract The purpose of this case report is to demonstrate surgical technique of only functional but symptomatic lingual thyroid gland transposition to submandibular region by transoral approach without mandibulotomy and tongue-splitting. A 37-year-old female patient was admitted to our hospital with dysphagia and apnea symptoms. Physical examination revealed 3cm×3cm lingual thyroid gland was detected at the tongue base. T... περισσότερα »
The Reliability of Oral and Pharyngeal Dimensions Captured with Acoustic Pharyngometry.
*The Reliability of Oral and Pharyngeal Dimensions Captured with Acoustic Pharyngometry.* Dysphagia. 2016 Jun 4; Authors: Molfenter SM Abstract Acoustic Pharyngometry (APh) is a method for quantifying oropharyngeal tract configuration using sound wave reflection and is commonly used in diagnostics and research of sleep apnea. The standard preset output of APh (minimal cross-sectional area) has been established as reliable. However, by conducting post-processing measures on specific breathing tasks, APh data can also reveal oral length, oral volume, pharyngeal length, and pharyng... περισσότερα »
Native language shapes automatic neural processing of speech.
*Native language shapes automatic neural processing of speech.* Neuropsychologia. 2016 Jun 1; Authors: Intartaglia B, White-Schwoch T, Meunier C, Roman S, Kraus N, Schön D Abstract The development of the phoneme kinventory is driven by the acoustic-phonetic properties of one's native language. Neural representation of speech is known to be shaped by language experience, as indexed by cortical responses, and recent studies suggest that subcortical processing also exhibits this attunement to native language. However, most work to date has focused on the differences between tonal an... περισσότερα »
Treatment of dysphasia with rTMS and language therapy after childhood stroke: Multimodal imaging of plastic change.
*Treatment of dysphasia with rTMS and language therapy after childhood stroke: Multimodal imaging of plastic change.* Brain Lang. 2016 Jun 2;159:23-34 Authors: Carlson HL, Jadavji Z, Mineyko A, Damji O, Hodge J, Saunders J, Hererro M, Nowak M, Patzelt R, Mazur-Mosiewicz A, MacMaster FP, Kirton A Abstract Expressive dysphasia accompanies left inferior frontal gyrus (IFG/Broca) injury. Recovery may relate to interhemispheric balance with homologous, contralesional IFG but is unexplored in children. We evaluated effects of inhibitory rTMS to contralesional IFG combined with intensive... περισσότερα »
Effectiveness of Clinical Supervision of Allied Health Professionals: A Survey.
*Effectiveness of Clinical Supervision of Allied Health Professionals: A Survey.* J Allied Health. 2016;45(2):113-121 Authors: Snowdon DA, Millard G, Taylor NF Abstract The practice of clinical supervision (CS) is recommended for allied health professionals. Preliminary evidence suggests that CS can be effective, but it is unknown for which allied health professions it is most effective. METHOD: The effectiveness of CS was measured using the allied health-specific modified Manchester Clinical Supervision Scale (MCSS-26). Subscales of the MCSS-26 were summed for three domain scores... περισσότερα »
The Neural Consequences of Age-Related Hearing Loss.
*The Neural Consequences of Age-Related Hearing Loss.* Trends Neurosci. 2016 Jun 1; Authors: Peelle JE, Wingfield A Abstract During hearing, acoustic signals travel up the ascending auditory pathway from the cochlea to auditory cortex; efferent connections provide descending feedback. In human listeners, although auditory and cognitive processing have sometimes been viewed as separate domains, a growing body of work suggests they are intimately coupled. Here, we review the effects of hearing loss on neural systems supporting spoken language comprehension, beginning with age-relat... περισσότερα »
Awareness and attitudes towards external auditory canal exostosis and its preventability in surfers in the UK: cross-sectional study
Research Articles S Morris, T Martin, D Mccahon, S Bennett The Journal of Laryngology & Otology,FirstView Article(s), 7 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #ENT via xlomafota13 on Inoreader http://ift.tt/1YaJBaM via IFTTT
IJMS, Vol. 17, Pages 889: Could Vitamin D Analogues Be Used to Target Leukemia Stem Cells?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 17 δευτερόλεπτα
Leukemic stem cells (LSCs) are defined as cells that possess the ability to self-renew and give rise to the differentiated cancer cells that comprise the tumor. These LSCs seem to show chemo-resistance and radio-resistance leading to the failure of conventional cancer therapies. Current therapies are directed at the fast growing tumor mass leaving the LSC […]
Absence of ALK and MET alterations in head and neck sarcomatoid carcinoma.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 17 δευτερόλεπτα
Absence of ALK and MET alterations in head and neck sarcomatoid carcinoma. Oral Oncol. 2016 Jun 1; Authors: Perrone F, Bossi P, Cortelazzi B, Dagrada GP, Paielli N, Licitra L, Pilotti S PMID: 27262592 [PubMed – as supplied by publisher] from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/212E8Sc via IFTTT
Robot‐assisted spleen preserving pancreatic surgery in MEN1 patients
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
ConclusionsMinimally invasive spleen‐preserving surgery in MEN1 patients is safe and feasible. Patients who underwent robot‐assisted surgery did not require conversion to open surgery. J. Surg. Oncol. © 2016 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1XwAlif via IFTTT
Surgical intervention during a Can’t Intubate Can’t Oxygenate (CICO) event: Emergency Front-of-neck Airway (FONA)?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Related Articles Surgical intervention during a Can’t Intubate Can’t Oxygenate (CICO) event: Emergency Front-of-neck Airway (FONA)? Clin Otolaryngol. 2016 May 30; Authors: Pracy JP, Brennan L, Cook TM, Hartle AJ, Marks RJ, McGrath BA, Narula A, Patel A PMID: 27241316 [PubMed – as supplied by publisher] from Anaesthesiology via xlomafota13 on Inoreader http://ift.tt/1U93IEC from #Med […]
Transport and dispersal of Stictococcus vayssierei (Homoptera, Stictococcidae) by Anoplolepis tenella (Hymenoptera, Formicidae)
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Dispersal can be a crucial factor affecting fitness in insects. We conducted a series of experiments and observations with the aim of determining the dispersal mode of the African root and tuber scale Stictococcus vayssierei, a pest on cassava in the Congo Basin. We monitored the main options of dispersal that occurred in scale insects: […]
Obstetric Anaesthetists’ Association and Difficult Airway Society guidelines for the management of difficult and failed tracheal intubation in obstetrics.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Related Articles Obstetric Anaesthetists’ Association and Difficult Airway Society guidelines for the management of difficult and failed tracheal intubation in obstetrics. Anaesthesia. 2015 Nov;70(11):1286-306 Authors: Mushambi MC, Kinsella SM, Popat M, Swales H, Ramaswamy KK, Winton AL, Quinn AC, Obstetric Anaesthetists’ Association, Difficult Airway Society Abstract The Obstetric Anaesthetists’ Association and Difficult Airway Society have […]
Boric acid for the suppression of the ant Anoplolepis tenella and effects on an associated scale insect pest Stictococcus vayssierei in cassava fields in the Congo Basin
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
The scale insect, Stictococcus vayssierei, is one of the major pests and constraints to cassava production in the Congo Basin. It is frequently found associated with the ground nesting ant, Anoplolepis tenella, under cassava plant. Amdro fire ant bait granules (contains 7.3 g/kg Hydramethylnon), borax and boric acid solution were evaluated in the laboratory for […]
Indications and results of emergency surgical airways performed by a physician-staffed helicopter emergency service.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Related Articles Indications and results of emergency surgical airways performed by a physician-staffed helicopter emergency service. Injury. 2015 May;46(5):787-90 Authors: Peters J, Bruijstens L, van der Ploeg J, Tan E, Hoogerwerf N, Edwards M Abstract BACKGROUND: Airway management is essential in critically ill or injured patients. In a «can’t intubate, can’t oxygenate» scenario, an emergency […]
Copper sulphate reduces the metabolic activity of Gammarus fossarum in laboratory and field experiments
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
The specialised fauna of freshwater springs is affected by contamination of the water with xenobiotics from human activities in the surrounding landscape. We assessed the effects of exposure to toxins in laboratory and field experiments by using copper sulphate as a model substance and Gammarus fossarum Koch, 1836, as the model organism. This amphipod is […]
The ‘Can’t intubate can’t oxygenate’ scenario in pediatric anesthesia: a comparison of the Melker cricothyroidotomy kit with a scalpel bougie technique.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Related Articles The ‘Can’t intubate can’t oxygenate’ scenario in pediatric anesthesia: a comparison of the Melker cricothyroidotomy kit with a scalpel bougie technique. Paediatr Anaesth. 2015 Apr;25(4):400-4 Authors: Prunty SL, Aranda-Palacios A, Heard AM, Chapman G, Ramgolam A, Hegarty M, Vijayasekaran S, von Ungern-Sternberg BS Abstract BACKGROUND: While the majority of pediatric intubations are uncomplicated, […]
Effects of increased temperatures on Gammarus fossarum under the influence of copper sulphate
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
The specialised fauna of freshwater springs will have to cope with a possible temperature rise owing to Global Change. It is affected additionally by contamination of the water with xenobiotics from human activities in the surrounding landscape. We assessed the combined effects of temperature increase and exposure to toxins in laboratory experiments by using copper […]
Cricothyrotomy performed with the Melker™ set or the QuickTrach™ kit: procedure times, learning curves and operators’ preference.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Related Articles Cricothyrotomy performed with the Melker™ set or the QuickTrach™ kit: procedure times, learning curves and operators’ preference. G Chir. 2014 Jul-Aug;35(7-8):165-70 Authors: Buonopane CE, Pasta V, Sottile D, Del Vecchio L, Maturo A, Merola R, Panunzi A, Urciuoli P, D’Orazi V Abstract BACKGROUND: Cricothyroidotomy is a surgical airway technique in which an airway […]
Awareness of human papilloma virus and cervical cancer prevention among Greek female healthcare workers.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Eur J Cancer Prev. 2016 May 31; Authors: Farazi PA, Hadji P, Roupa Z Abstract The incidence rate of cervical cancer varies by geographic region, with less developed regions showing the highest rates. All risk factors for cervical cancer are actually preventable if appropriate lifestyle changes are adopted. In addition, vaccines protecting against the majority […]
The new 9-valent vaccine for human papillomavirus prevention.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Update on the new 9-valent vaccine for human papillomavirus prevention.: Can Fam Physician. 2016 May;62(5):399-402 Authors: Yang DY, Bracken K Abstract OBJECTIVE: To provide family physicians with information on the efficacy, safety, public health effects, and cost-effectiveness of the 9-valent human papillomavirus (HPV) vaccine. QUALITY OF EVIDENCE: Relevant publications in PubMed up to May 2015 […]
16S rRNA amplicon sequencing identifies microbiota associated with oral cancer, Human Papilloma Virus infection and surgical treatment.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Authors: Guerrero-Preston R, Godoy-Vitorino F, Jedlicka A, Rodríguez-Hilario A, González H, Bondy J, Lawson F, Folawiyo O, Michailidi C, Dziedzic A, Thangavel R, Hadar T, Noordhuis MG, Westra W, Koch W, Sidransky D Abstract Systemic inflammatory events and localized disease, mediated by the microbiome, may be measured in saliva as head and neck squamous cell […]
The ‘Can’t intubate can’t oxygenate’ scenario in pediatric anesthesia
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
a comparison of the Melker cricothyroidotomy kit with a scalpel bougie technique.: Authors: Prunty SL, Aranda-Palacios A, Heard AM, Chapman G, Ramgolam A, Hegarty M, Vijayasekaran S, von Ungern-Sternberg BS Abstract BACKGROUND: While the majority of pediatric intubations are uncomplicated, the ‘Can’t intubate, Can’t Oxygenate’ scenario (CICO) does occur. With limited management guidelines available, CICO […]
Autonomic nervous system function predicts the inflammatory response over three years in newly diagnosed ulcerative colitis patients
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Abstract Background The autonomic nervous system (ANS) modulates intestinal inflammation in animal models. Human evidence confirming such modulating influence is limited. We aimed to investigate whether ANS function is associated with inflammatory parameters at disease onset, and whether it predicts the evolution of inflammation in patients with ulcerative colitis (UC). Methods We prospectively monitored 51 […]
Anticancer Res Table of Contents for June 2016; Vol. 36, No. 6
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 24 δευτερόλεπτα
HOME CURRENT ISSUE PAST ISSUES SUBSCRIBE ALERTS IIAR JOURNALS CONFERENCES CONTACT US HELP Anticancer Research June 2016; 36 (6)
Transport and dispersal of Stictococcus vayssierei (Homoptera, Stictococcidae) by Anoplolepis tenella (Hymenoptera, Formicidae)
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 24 δευτερόλεπτα
Dispersal can be a crucial factor affecting fitness in insects. We conducted a series of experiments and observations with the aim of determining the dispersal mode of the African root and tuber scale Stictococcus vayssierei, a pest on cassava in the Congo Basin. We monitored the main options of dispersal that occurred in scale insects: […]
Boric acid for the suppression of the ant Anoplolepis tenella and effects on an associated scale insect pest Stictococcus vayssierei in cassava fields in the Congo Basin
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 24 δευτερόλεπτα
The scale insect, Stictococcus vayssierei, is one of the major pests and constraints to cassava production in the Congo Basin. It is frequently found associated with the ground nesting ant, Anoplolepis tenella, under cassava plant. Amdro fire ant bait granules (contains 7.3 g/kg Hydramethylnon), borax and boric acid solution were evaluated in the laboratory for […]
Copper sulphate reduces the metabolic activity of Gammarus fossarum in laboratory and field experiments
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 24 δευτερόλεπτα
The specialised fauna of freshwater springs is affected by contamination of the water with xenobiotics from human activities in the surrounding landscape. We assessed the effects of exposure to toxins in laboratory and field experiments by using copper sulphate as a model substance and Gammarus fossarum Koch, 1836, as the model organism. This amphipod is […]
Effects of increased temperatures on Gammarus fossarum under the influence of copper sulphate
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 24 δευτερόλεπτα
The specialised fauna of freshwater springs will have to cope with a possible temperature rise owing to Global Change. It is affected additionally by contamination of the water with xenobiotics from human activities in the surrounding landscape. We assessed the combined effects of temperature increase and exposure to toxins in laboratory experiments by using copper […]
Temperature effects on the feeding and electron transport system (ETS) activity of Gammarus fossarum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 24 δευτερόλεπτα
The effects of an increase in water temperature as a direct consequence of global change on organisms living in springs and spring brooks have rarely been studied in laboratory experiments. In this study, experiments were conducted to test the response of Gammarus fossarum Koch, 1836, as an abundant representative of the European spring fauna, to […]
Macroinvertebrate assemblages of natural springs along an altitudinal gradient in the Bernese Alps, Switzerland
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 24 δευτερόλεπτα
Alpine springs are sensitive ecotones which are inhabited by highly adapted organisms. Studies on how the species assemblages change vertically have not been conducted previously. We investigated 35 natural springs along an altitudinal gradient of about 2000 m in a valley in the Bernese Alps over 2 years. The aim of this study was to […]
Taxes in Cities
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 24 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1X6BDQh via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Schutzwürdigkeit des Embryos: Allgemeine Begründungen und die Konzeption im Entwurf zum Embryo nenforschungsgesetz
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 24 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Zr3nNE via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Regulation of the Pacemaker Activity of Colonic Interstitial Cells of Cajal by Protease-Activated Receptors: Involvement of Hyperpolarization-Activated Cyclic Nucleotide Channels
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 24 δευτερόλεπτα
Background and Purpose: The exact mechanism of protease-activated receptors (PARs) on pacemaker activity of interstitial cells of Cajal (ICCs) has not been reported. We investigated the effects on pacemaker activity by the activation of PARs and its signal mechanisms in colonic ICCs. Methods: The whole-cell patch-clamp technique, RT-PCR and Ca2+ imaging were used in cultured […]
The Reliability of Oral and Pharyngeal Dimensions Captured with Acoustic Pharyngometry.
*The Reliability of Oral and Pharyngeal Dimensions Captured with Acoustic Pharyngometry.* Dysphagia. 2016 Jun 4; Authors: Molfenter SM Abstract Acoustic Pharyngometry (APh) is a method for quantifying oropharyngeal tract configuration using sound wave reflection and is commonly used in diagnostics and research of sleep apnea. The standard preset output of APh (minimal cross-sectional area) has been established as reliable. However, by conducting post-processing measures on specific breathing tasks, APh data can also reveal oral length, oral volume, pharyngeal length, and pharyng... περισσότερα »
The Reliability of Oral and Pharyngeal Dimensions Captured with Acoustic Pharyngometry.
*The Reliability of Oral and Pharyngeal Dimensions Captured with Acoustic Pharyngometry.* Dysphagia. 2016 Jun 4; Authors: Molfenter SM Abstract Acoustic Pharyngometry (APh) is a method for quantifying oropharyngeal tract configuration using sound wave reflection and is commonly used in diagnostics and research of sleep apnea. The standard preset output of APh (minimal cross-sectional area) has been established as reliable. However, by conducting post-processing measures on specific breathing tasks, APh data can also reveal oral length, oral volume, pharyngeal length, and pharyng... περισσότερα »
Native language shapes automatic neural processing of speech.
*Native language shapes automatic neural processing of speech.* Neuropsychologia. 2016 Jun 1; Authors: Intartaglia B, White-Schwoch T, Meunier C, Roman S, Kraus N, Schön D Abstract The development of the phoneme kinventory is driven by the acoustic-phonetic properties of one's native language. Neural representation of speech is known to be shaped by language experience, as indexed by cortical responses, and recent studies suggest that subcortical processing also exhibits this attunement to native language. However, most work to date has focused on the differences between tonal an... περισσότερα »
Treatment of dysphasia with rTMS and language therapy after childhood stroke: Multimodal imaging of plastic change.
*Treatment of dysphasia with rTMS and language therapy after childhood stroke: Multimodal imaging of plastic change.* Brain Lang. 2016 Jun 2;159:23-34 Authors: Carlson HL, Jadavji Z, Mineyko A, Damji O, Hodge J, Saunders J, Hererro M, Nowak M, Patzelt R, Mazur-Mosiewicz A, MacMaster FP, Kirton A Abstract Expressive dysphasia accompanies left inferior frontal gyrus (IFG/Broca) injury. Recovery may relate to interhemispheric balance with homologous, contralesional IFG but is unexplored in children. We evaluated effects of inhibitory rTMS to contralesional IFG combined with intensive... περισσότερα »
Effectiveness of Clinical Supervision of Allied Health Professionals: A Survey.
*Effectiveness of Clinical Supervision of Allied Health Professionals: A Survey.* J Allied Health. 2016;45(2):113-121 Authors: Snowdon DA, Millard G, Taylor NF Abstract The practice of clinical supervision (CS) is recommended for allied health professionals. Preliminary evidence suggests that CS can be effective, but it is unknown for which allied health professions it is most effective. METHOD: The effectiveness of CS was measured using the allied health-specific modified Manchester Clinical Supervision Scale (MCSS-26). Subscales of the MCSS-26 were summed for three domain scores... περισσότερα »
The use of ultrasound to guide time-critical cannula tracheotomy when anterior neck airway anatomy is unidentifiable.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *The use of ultrasound to guide time-critical cannula tracheotomy when anterior neck airway anatomy is unidentifiable.* Eur J Anaesthesiol. 2011 Jul;28(7):506-10 Authors: Dinsmore J, Heard AM, Green RJ Abstract BACKGROUND AND OBJECTIVE: Transtracheal or transcricothyroid placement of a cannula is a practice used in a number of aspects of airway management in anaesthesia and intensive care. In this study, we aimed to investigate whether the use of ultrasound will facilitate cannula placement in a time-critical situ... περισσότερα »
Matteo non ce l’ha fatta, stroncato da un male incurabile a soli 37 anni
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 31 δευτερόλεπτα
Aveva solo 37 anni ed una vita davanti a sè ma un’improvvisa ricaduta gli è stata fatale. Matteo Cesaretto non ce l’ha fatta. Come riporta il quotidiano Il from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1tbtEFJ via IFTTT
Prof Karim Fizazi chairs a discussion on the prostate cancer news from #ASCO16 https://t.co/6bQYCJqcAb https://t.co/VQDyjgGYQf
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 31 δευτερόλεπτα
Prof Karim Fizazi chairs a discussion on the prostate cancer news from #ASCO16 https://t.co/6bQYCJqcAb https://t.co/VQDyjgGYQf from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://twitter.com/ecancer/status/739767574884458496 via IFTTT
New authority to oversee NHS complaints system must be independent, say MPs
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 31 δευτερόλεπτα
The body created to oversee and improve the NHS complaints system must be allowed real independence outside NHS control, MPs have said.MPs on the parliamentary public administration and… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/28f29Lg via IFTTT
Bilateral V-Y flap for a perianal basal cell carcinoma: A case report.
*Bilateral V-Y flap for a perianal basal cell carcinoma: A case report.* Int J Surg Case Rep. 2016 Jun 2;24:153-155 Authors: Rivera-Chavarría JP, Vargas-Villalobos F, Riggioni-Víquez S Abstract BACKGROUND: Basal cell carcinomas are rare in non-sun-exposed skin, and are even rarer in the perianal region. Alertness to the unusual occurrence of this tumor at perianal site, with understanding of its clinical course, can prevent delay in its diagnosis and morbid aggressiveness in the management of the disease. PRESENTATION OF CASE: A 93 year old female, referred to our hospital because... περισσότερα »
A primary cellular fibrohistiocytoma of the lung: Report of a case.
*A primary cellular fibrohistiocytoma of the lung: Report of a case.* Int J Surg Case Rep. 2016 May 11;24:150-152 Authors: Ichiki Y, Kawasaki J, Hamatsu T, Suehiro T, Tanaka F, Hisaoka M, Sugimachi K Abstract INTRODUCTION: Cellular fibrohistiocytoma (CFH) is a type of fibrohistiocytic tumor that commonly occurs in the dermis and superficial subcutis. The designation is used for lesions that show increased cellularity with a fascicular growth pattern and frequent extension. Our search of literature only revealed one case of a primary CFH of the lung. We experienced a rare patient ... περισσότερα »
Inflammatory myofibroblastic tumor presenting as ileocecal intussusception-A case report.
*Inflammatory myofibroblastic tumor presenting as ileocecal intussusception-A case report.* Int J Surg Case Rep. 2016 May 19;24:146-149 Authors: Paiva C, Soares F, da Inez Correia R, Valente V Abstract INTRODUCTION: Inflammatory myofibroblastic tumor (IMFT) is an uncommon mesenchymal solid tumor commonly documented in children and young adults. It is usually located in lungs however, extrapulmonary involvement has also been reported. Here we report a case of IMFT presenting as an ileocecal intussusception. PRESENTATION OF CASE: A 55-year-old man presented with a two months history... περισσότερα »
Sepsis 4.0: Understanding sepsis-HLH overlap syndrome
[image: cytostorm2.gif?resize=750%2C357] Since the 1980s it has been recognized that some patients with sepsis also develop hemophagocytic lymphocytosis. For decades this was believed to be extremely rare. However, currently there is increasing recognition that this combination might represent a significant fraction of sepsis patients. EMCrit by Josh Farkas. from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1U8TFza via IFTTT
Sepsis 4.0: Understanding sepsis-HLH overlap syndrome
[image: cytostorm2.gif?resize=750%2C357] Since the 1980s it has been recognized that some patients with sepsis also develop hemophagocytic lymphocytosis. For decades this was believed to be extremely rare. However, currently there is increasing recognition that this combination might represent a significant fraction of sepsis patients. EMCrit by Josh Farkas. from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1U8TFza via IFTTT
Medication Palatability Affects Physician Prescribing Preferences for Common Pediatric Conditions
[image: cover.gif?v=1&s=a69cedb9789cb8bbbf032b71] Abstract Objectives The objective of this study was to determine if physicians would alter their prescribing preferences after sampling liquid formulations of medications for common pediatric diagnoses. Methods This was a prospective interventional before/after study conducted at an academic medical center in the United States. The participants of interest included emergency, family medicine, and pediatric physicians. Participants initially completed a brief survey for their primary oral liquid medication of choice for the treatmen... περισσότερα »
Efficacy of a Universal Brief Intervention for Violence Among Urban Emergency Department Youth
Abstract Background Violent injury is the leading cause of death among urban youth. Emergency department (ED) visits represent an opportunity to deliver a brief intervention (BI) to reduce violence among youth seeking medical care in high-risk communities. Objective To determine the efficacy of a universally applied Brief Intervention (BI) addressing violence behaviors among youth presenting to an urban ED. Methods ED youth (14-to-20 years-old) seeking medical or injury- related care in a Level-1 ED (October 2011–March 2015) and screening positive for a home address within the inte... περισσότερα »
The Neural Consequences of Age-Related Hearing Loss.
*The Neural Consequences of Age-Related Hearing Loss.* Trends Neurosci. 2016 Jun 1; Authors: Peelle JE, Wingfield A Abstract During hearing, acoustic signals travel up the ascending auditory pathway from the cochlea to auditory cortex; efferent connections provide descending feedback. In human listeners, although auditory and cognitive processing have sometimes been viewed as separate domains, a growing body of work suggests they are intimately coupled. Here, we review the effects of hearing loss on neural systems supporting spoken language comprehension, beginning with age-relat... περισσότερα »
Native language shapes automatic neural processing of speech.
*Native language shapes automatic neural processing of speech.* Neuropsychologia. 2016 Jun 1; Authors: Intartaglia B, White-Schwoch T, Meunier C, Roman S, Kraus N, Schön D Abstract The development of the phoneme kinventory is driven by the acoustic-phonetic properties of one's native language. Neural representation of speech is known to be shaped by language experience, as indexed by cortical responses, and recent studies suggest that subcortical processing also exhibits this attunement to native language. However, most work to date has focused on the differences between tonal an... περισσότερα »
Treatment of dysphasia with rTMS and language therapy after childhood stroke: Multimodal imaging of plastic change.
*Treatment of dysphasia with rTMS and language therapy after childhood stroke: Multimodal imaging of plastic change.* Brain Lang. 2016 Jun 2;159:23-34 Authors: Carlson HL, Jadavji Z, Mineyko A, Damji O, Hodge J, Saunders J, Hererro M, Nowak M, Patzelt R, Mazur-Mosiewicz A, MacMaster FP, Kirton A Abstract Expressive dysphasia accompanies left inferior frontal gyrus (IFG/Broca) injury. Recovery may relate to interhemispheric balance with homologous, contralesional IFG but is unexplored in children. We evaluated effects of inhibitory rTMS to contralesional IFG combined with intensive... περισσότερα »
Effectiveness of Clinical Supervision of Allied Health Professionals: A Survey.
*Effectiveness of Clinical Supervision of Allied Health Professionals: A Survey.* J Allied Health. 2016;45(2):113-121 Authors: Snowdon DA, Millard G, Taylor NF Abstract The practice of clinical supervision (CS) is recommended for allied health professionals. Preliminary evidence suggests that CS can be effective, but it is unknown for which allied health professions it is most effective. METHOD: The effectiveness of CS was measured using the allied health-specific modified Manchester Clinical Supervision Scale (MCSS-26). Subscales of the MCSS-26 were summed for three domain scores... περισσότερα »
The Neural Consequences of Age-Related Hearing Loss.
*The Neural Consequences of Age-Related Hearing Loss.* Trends Neurosci. 2016 Jun 1; Authors: Peelle JE, Wingfield A Abstract During hearing, acoustic signals travel up the ascending auditory pathway from the cochlea to auditory cortex; efferent connections provide descending feedback. In human listeners, although auditory and cognitive processing have sometimes been viewed as separate domains, a growing body of work suggests they are intimately coupled. Here, we review the effects of hearing loss on neural systems supporting spoken language comprehension, beginning with age-relat... περισσότερα »
Awareness and attitudes towards external auditory canal exostosis and its preventability in surfers in the UK: cross-sectional study
Research Articles S Morris, T Martin, D Mccahon, S Bennett The Journal of Laryngology & Otology,FirstView Article(s), 7 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #ENT via xlomafota13 on Inoreader http://ift.tt/1YaJBaM via IFTTT
Awareness and attitudes towards external auditory canal exostosis and its preventability in surfers in the UK: cross-sectional study
Research Articles S Morris, T Martin, D Mccahon, S Bennett The Journal of Laryngology & Otology,FirstView Article(s), 7 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #ENT via xlomafota13 on Inoreader http://ift.tt/1YaJBaM via IFTTT
Autonomic nervous system function predicts the inflammatory response over three years in newly diagnosed ulcerative colitis patients
Abstract Background The autonomic nervous system (ANS) modulates intestinal inflammation in animal models. Human evidence confirming such modulating influence is limited. We aimed to investigate whether ANS function is associated with inflammatory parameters at disease onset, and whether it predicts the evolution of inflammation in patients with ulcerative colitis (UC). Methods We prospectively monitored 51 patients from onset of UC for 3 years. Upon remission of the onset flare, ANS activity was assessed by heart rate variability analysis and compared with healthy controls. Infl... περισσότερα »
Autonomic nervous system function predicts the inflammatory response over three years in newly diagnosed ulcerative colitis patients
Abstract Background The autonomic nervous system (ANS) modulates intestinal inflammation in animal models. Human evidence confirming such modulating influence is limited. We aimed to investigate whether ANS function is associated with inflammatory parameters at disease onset, and whether it predicts the evolution of inflammation in patients with ulcerative colitis (UC). Methods We prospectively monitored 51 patients from onset of UC for 3 years. Upon remission of the onset flare, ANS activity was assessed by heart rate variability analysis and compared with healthy controls. Infl... περισσότερα »
Persistent 'can't intubate, can't oxygenate' crisis despite reversal of rocuronium with sugammadex: the importance of timing.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 44 δευτερόλεπτα
Related Articles *Persistent 'can't intubate, can't oxygenate' crisis despite reversal of rocuronium with sugammadex: the importance of timing.* Anaesth Intensive Care. 2012 Jul;40(4):722 Authors: Curtis RP PMID: 22813507 [PubMed - indexed for MEDLINE] from Anaesthesiology via xlomafota13 on Inoreader http://ift.tt/25H4xYX via IFTTT
A persistent 'can't intubate, can't oxygenate' crisis despite rocuronium reversal with sugammadex.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 44 δευτερόλεπτα
Related Articles *A persistent 'can't intubate, can't oxygenate' crisis despite rocuronium reversal with sugammadex.* Anaesth Intensive Care. 2012 Mar;40(2):344-6 Authors: Kyle BC, Gaylard D, Riley RH Abstract A 'can't intubate, can't oxygenate' airway crisis is a rare event which most anaesthetists will never experience during their career(1,2). This report highlights the outcome of time-critical decisions in a potential airway catastrophe. Rocuronium was used as an alternative muscle relaxant for rapid sequence induction. The use of sugammadex in 'can't intubate, can't oxygena... περισσότερα »
Emergency surgical airway in life-threatening acute airway emergencies--why are we so reluctant to do it?
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 44 δευτερόλεπτα
Related Articles *Emergency surgical airway in life-threatening acute airway emergencies--why are we so reluctant to do it?* Anaesth Intensive Care. 2011 Jul;39(4):578-84 Authors: Greenland KB, Acott C, Segal R, Goulding G, Riley RH, Merry AF Abstract 'Can't intubate, can't oxygenate' scenarios are rare but are often poorly managed, with potentially disastrous consequences. In our opinion, all doctors should be able to create a surgical airway if necessary. More practically, at least all anaesthetists should have this ability. There should be a change in culture to one that encou... περισσότερα »
The use of ultrasound to guide time-critical cannula tracheotomy when anterior neck airway anatomy is unidentifiable.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 44 δευτερόλεπτα
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *The use of ultrasound to guide time-critical cannula tracheotomy when anterior neck airway anatomy is unidentifiable.* Eur J Anaesthesiol. 2011 Jul;28(7):506-10 Authors: Dinsmore J, Heard AM, Green RJ Abstract BACKGROUND AND OBJECTIVE: Transtracheal or transcricothyroid placement of a cannula is a practice used in a number of aspects of airway management in anaesthesia and intensive care. In this study, we aimed to investigate whether the use of ultrasound will facilitate cannula placement in a time-critical situ... περισσότερα »
Simultaneous anterior and posterior serosal mapping of gastric slow wave dysrhythmias induced by vasopressin
Background: High-resolution (HR) mapping enables mechanistic insights into gastric slow wave dysrhythmias and is now achieving clinical translation. However, previous studies have focused mainly on dysrhythmias occurring on the anterior gastric wall. The present study simultaneously mapped the anterior and posterior gastric serosa during episodes of dysrhythmias induced by vasopressin to aid understanding of dysrhythmia initiation, maintenance and termination. Methods: HR mapping (8×16 electrodes on each serosa; 20–74 cm2) was performed in anesthetized subjects. Baseline recording... περισσότερα »
The dynamic relationship between cerebellar Purkinje cell simple spikes and complex spike spikelet number
Purkinje cells are central to cerebellar function as they form the sole output of the cerebellar cortex. They exhibit two distinct types of action potential: simple spikes and complex spikes, and it is widely accepted that interaction between these two types of impulse is central to cerebellar cortical information processing. Previous investigations of the interactions between simple spikes and complex spikes have mainly considered complex spikes as unitary events. However, complex spikes are composed of an initial large spike followed by a number of secondary components, termed s... περισσότερα »
Clinical significance of intra-nodal naevi in sentinel node biopsies for malignant melanoma.
*Clinical significance of intra-nodal naevi in sentinel node biopsies for malignant melanoma.* Eur J Surg Oncol. 2016 May 19; Authors: Smith OJ, Coelho JA, Trevatt AE, Ross GL Abstract BACKGROUND: Intra-nodal naevi (INN) identified during assessment of a sentinel lymph node for melanoma are not an uncommon finding. Little is known about their clinical significance. Patients with INN are treated as sentinel node biopsy (SNB) negative currently. Our aim was to assess the significance of INN in patients who undergo SNB for melanoma. METHODS: 353 melanoma patients who underwent a SNB ... περισσότερα »
Basal cell skin cancer and the risk of second primary cancers: a cancer registry-based study in Lithuania.
*Basal cell skin cancer and the risk of second primary cancers: a cancer registry-based study in Lithuania.* Ann Epidemiol. 2016 May 12; Authors: Krilaviciute A, Vincerzevskiene I, Smailyte G Abstract PURPOSE: The aim of this population-based cohort study was to determine the risk of second primary cancer in basal cell carcinoma (BCC) patients in Lithuania. METHODS: This analysis was based on patients diagnosed with BCC in Lithuania between 1998 and 2007 and followed until 2011. Standardized incidence ratios for subsequent cancers as a ratio of observed number of cancer cases in ... περισσότερα »
Management of High-Risk Squamous Cell Carcinoma of the Skin.
*Management of High-Risk Squamous Cell Carcinoma of the Skin.* Curr Treat Options Oncol. 2016 Jul;17(7):34 Authors: Fu T, Aasi SZ, Hollmig ST Abstract OPINION STATEMENT: Non-melanoma skin cancer (NMSC) is the most common malignancy in the USA, with cutaneous squamous cell carcinomas (cSCCs) constituting approximately 20 % of all NMSC. While cSCCs typically behave in an indolent fashion and can be cured with local destructive or surgical methods, a small subset metastasizes and induces significant morbidity and mortality. Identifying and aggressively treating these "high-risk" cSCC... περισσότερα »
Chemical excitation of electrons: A dark path to melanoma.
*Chemical excitation of electrons: A dark path to melanoma.* DNA Repair (Amst). 2016 Jun 1; Authors: Premi S, Brash DE Abstract Sunlight's ultraviolet wavelengths induce cyclobutane pyrimidine dimers (CPDs), which then cause mutations that lead to melanoma or to cancers of skin keratinocytes. In pigmented melanocytes, we found that CPDs arise both instantaneously and for hours after UV exposure ends. Remarkably, the CPDs arising in the dark originate by a novel pathway that resembles bioluminescence but does not end in light: First, UV activates the enzymes nitric oxide synthase ... περισσότερα »
Nevoid iris melanoma, case report.
*Nevoid iris melanoma, case report.* Arch Soc Esp Oftalmol. 2016 Jun 1; Authors: Saldaña-Garrido JD, Martínez-Hergueta MC, Martínez-Rubio MM Abstract CASE REPORT: The case is presented of a patient with diagnosis of iris nevus in the left eye in youth with a poor follow-up, who referred a decreased visual acuity in that eye. A hyphaema and a 3×4×3mm nodule with irregular pigmentation was observed. Excision of the tumour and histological analysis confirmed the suspicion of iris melanoma in stage Ia. DISCUSSION: Despite the low grade malignancy of iris melanoma and the low frequency... περισσότερα »
Resistance to ursolic acid-induced apoptosis through involvement of melanogenesis and COX-2/PGE2 pathways in human M4Beu melanoma cancer cells.
*Resistance to ursolic acid-induced apoptosis through involvement of melanogenesis and COX-2/PGE2 pathways in human M4Beu melanoma cancer cells.* Exp Cell Res. 2016 Jun 1; Authors: Hassan L, Pinon A, Limami Y, Seeman J, Fidanzi-Dugas C, Martin F, Badran B, Simon A, Liagre B Abstract Melanoma is one of the most aggressive forms of cancer with a continuously growing incidence worldwide and is usually resistant to chemotherapy agents, which is due in part to a strong resistance to apoptosis. Previously, we had showed that B16-F0 murine melanoma cells undergoing apoptosis are able to... περισσότερα »
High-level secretory expression and purification of recombinant human interleukin 1 beta in Pichia pastoris.
*High-level secretory expression and purification of recombinant human interleukin 1 beta in Pichia pastoris.* Protein Pept Lett. 2016 May 30; Authors: Li P, Yang G, Geng X, Li B, Wang Z, Zhang Q, Yang Y, Xu C Abstract As an important pro-inflammatory cytokine, interleukin-1beta (IL-1β) participates in a variety of physiological and pathological responses. In order to obtain higher yielded recombinant human interleukin-1 beta (rhIL-1β), we cloned hIL-1β cDNA sequences based on the coding sequence of human mature IL-1β. After recombinant pPICZαA/hIL-1β was separated and sequenced,... περισσότερα »
Age and clear eyes are associated with an increased risk of cutaneous squamous cell carcinomas in vemurafenib-treated melanoma patients.
Cutaneous squamous cell carcinoma (cSCC) is a frequent side-effect of vemurafenib treatment. The main aim of this study was to identify the clinical risk factors associated with the development of cSCC in melanoma patients treated with vemurafenib. We carried out a retrospective study, including 63 consecutive melanoma patients treated with vemurafenib for BRAF-mutant metastatic melanoma in an oncodermatological department. Clinical and follow-up data were collected and analysed, and a comparison of the subgroups who did and did not develop cSCC was performed. A total of 42.9% of pa... περισσότερα »
Tumor Heterogeneity and Therapeutic Resistance.
*Tumor Heterogeneity and Therapeutic Resistance.* Am Soc Clin Oncol Educ Book. 2016;35:e585-e593 Authors: Lovly CM, Salama AK, Salgia R Abstract The rapidly changing landscape of oncology has brought new light, and with it, new challenges to optimizing therapeutic strategies for patients. Although the concept of patient heterogeneity is well known to any practicing clinician, a more detailed understanding of the biologic changes that underscore the clinical picture is beginning to emerge. Thus, tumor heterogeneity has come to encompass more than just the clinical picture and can ... περισσότερα »
Targeted Therapy in Brain Metastases: Ready for Primetime?
*Targeted Therapy in Brain Metastases: Ready for Primetime?* Am Soc Clin Oncol Educ Book. 2016;35:e123-e130 Authors: Venur VA, Ahluwalia MS Abstract Brain metastasis is a serious complication of cancer that causes significant morbidity for patients. Over the last decade, numerous new driver somatic mutations have been recognized and targeted therapies are changing the landscape of treatment in lung cancer, breast cancer, and melanoma, which are also the three most common cancers that result in brain metastases. The common actionable mutations include the EGFR mutation and anaplas... περισσότερα »
Immune Checkpoint Inhibitors in Brain Metastases: From Biology to Treatment.
*Immune Checkpoint Inhibitors in Brain Metastases: From Biology to Treatment.* Am Soc Clin Oncol Educ Book. 2016;35:e116-e122 Authors: Berghoff AS, Venur VA, Preusser M, Ahluwalia MS Abstract Cancer immunotherapy has been a subject of intense research over the last several years, leading to new approaches for modulation of the immune system to treat malignancies. Immune checkpoint inhibitors (anti-CLTA-4 antibodies and anti-PD-1/PD-L1 antibodies) potentiate the host's own antitumor immune response. These immune checkpoint inhibitors have shown impressive clinical efficacy in adva... περισσότερα »
Surgical Management and Adjuvant Therapy for High-Risk and Metastatic Melanoma.
*Surgical Management and Adjuvant Therapy for High-Risk and Metastatic Melanoma.* Am Soc Clin Oncol Educ Book. 2016;35:e505-e514 Authors: van Akkooi AC, Atkins MB, Agarwala SS, Lorigan P Abstract Wide local excision is considered routine therapy after initial diagnosis of primary melanoma to reduce local recurrences, but it does not impact survival. Sentinel node staging is recommended for melanomas of intermediate thickness, but it has also not demonstrated any indisputable therapeutic effect on survival. The prognostic value of sentinel node staging has been long established an... περισσότερα »
Current State of Immune-Based Therapies for Glioblastoma.
*Current State of Immune-Based Therapies for Glioblastoma.* Am Soc Clin Oncol Educ Book. 2016;35:e132-e139 Authors: Lim M, Weller M, Chiocca EA Abstract Glioblastoma is one of the most aggressive solid tumors, and, despite treatment options such as surgery, radiation, and chemotherapy, its prognosis remains grim. Novel approaches are needed to improve survival. Immunotherapy has proven efficacy for melanoma, lung cancer, and kidney cancer and is now a focus for glioblastoma. In this article, glioblastoma-mediated immunosuppression will be discussed and two exciting immune approac... περισσότερα »
Endocrinological side-effects of immune checkpoint inhibitors
[image: image]Purpose of review: Three mAbs targeting immune checkpoint proteins are available for the treatment of patients with melanoma, lung, and kidney cancer, and their use will likely expand in the future to additional tumor types. We here update the literature on the incidence and pathophysiology of endocrine toxicities induced by these agents, and discuss management guidance. Recent findings: Immune checkpoint inhibition may trigger autoimmune syndromes involving different organs, including several endocrine glands (pituitary, thyroid, adrenals, and endocrine pancreas). Hyp... περισσότερα »
Dermatologic complications of anti-PD-1/PD-L1 immune checkpoint antibodies
[image: image]Purpose of review: The therapeutic use of anti-PD-1/PD-L1 antibodies (nivolumab, pembrolizumab) is rapidly increasing. Given their mechanism of action that triggers T-cell activation, these immune checkpoint inhibitors induce specific adverse events that are mostly of immunologic origin. In this way, cutaneous toxicities represent the most frequent immune-related adverse events (irAEs). The purpose of this review is to summarize the most prevalent dermatologic complications induced by PD-1/PD-L1 immune checkpoint-blocking antibodies and to compare their dermatologic sa... περισσότερα »
Side-effects of checkpoint inhibitor-based combination therapy
[image: image]Purpose of review: After the dramatic and often long-standing response rates of checkpoint inhibitors as single agents, the new era for checkpoint inhibitors is combined therapy (either with other checkpoint inhibitors, chemotherapies, targeted therapies or immunotherapies) that is aiming to do even better. Although one can speculate that these combinations will result in improved results, high cost and potential toxicity are limiting factors for their use. In this review, we plan to report on the different side-effects of the checkpoint inhibitor-based combination the... περισσότερα »
Ocular and orbital side-effects of checkpoint inhibitors: a review article
[image: image]Purpose of review: Checkpoint inhibitors have been increasingly considered as new targets for cancer therapies. Patients receiving checkpoint inhibitors develop many immune-related adverse events (IRAEs). However, ophthalmic IRAEs are rare and have been reported in less than 1% of patients. To date, few case reports evaluating the ophthalmological side-effects of checkpoint inhibitors have been published. In this review, we plan to report the different ocular and orbital side-effects of the checkpoint inhibitors, and to help guide ophthalmologists and oncologists in th... περισσότερα »
European Research on Electrochemotherapy in Head and Neck Cancer (EURECA) project: Results of the treatment of skin cancer
Publication date: August 2016 *Source:*European Journal of Cancer, Volume 63 Author(s): Giulia Bertino, Gregor Sersa, Francesca De Terlizzi, Antonio Occhini, Christina Caroline Plaschke, Ales Groselj, Cristobal Langdon, Juan J. Grau, James A. McCaul, Derrek Heuveling, Maja Cemazar, Primoz Strojan, Remco de Bree, C. Renè Leemans, Irene Wessel, Julie Gehl, Marco Benazzo Electrochemotherapy is an effective and safe method for local treatment of cutaneous and subcutaneous tumours, where electric pulses cause increased permeability of cell membranes in the tumour mass, enabling dramatically... περισσότερα »
Management of High-Risk Squamous Cell Carcinoma of the Skin
Opinion Statement Non-melanoma skin cancer (NMSC) is the most common malignancy in the USA, with cutaneous squamous cell carcinomas (cSCCs) constituting approximately 20 % of all NMSC. While cSCCs typically behave in an indolent fashion and can be cured with local destructive or surgical methods, a small subset metastasizes and induces significant morbidity and mortality. Identifying and aggressively treating these “high-risk” cSCCs (HRcSCCs) is thus paramount. Recent improvements in staging cSCCs appear to offer better risk stratification than earlier staging criteria. Radiologic i... περισσότερα »
Different dose rate-dependent responses of human melanoma cells and fibroblasts to low dose fast neutrons
10.1080/09553002.2016.1186300<br>Claude Dionet from Melanoma via xlomafota13 on Inoreader http://ift.tt/1Y7MLvZ
Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model.* PLoS One. 2015;10(10):e0140744 Authors: Galvan DL, O'Neil RT, Foster AE, Huye L, Bear A, Rooney CM, Wilson MH Abstract Adoptive transfer of gene modified T cells provides possible immunotherapy for patients with cancers refractory to other treatments. We have previously used the non-viral piggyBac transposon system to gene modify human T cells for potential immuno... περισσότερα »
Audiovestibular disorders as autoimmune reaction in patients with melanoma.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Audiovestibular disorders as autoimmune reaction in patients with melanoma.* Med Hypotheses. 2015 Sep;85(3):336-8 Authors: Barozzi S, Ginocchio D, Socci M, Alpini D, Cesarani A Abstract Melanoma is an aggressive form of cancer derived from neuroectodermal melanocytes. Melanocytes are present in the skin and hair follicles, as well as in the eye (iris and choroids), the leptomeninges, the anal canal and the inner ear. In the inner ear melanocytes are found both in the intermediate layer of the stria vascularis of t... περισσότερα »
Sepsis 4.0: Understanding sepsis-HLH overlap syndrome
[image: cytostorm2.gif?resize=750%2C357] Since the 1980s it has been recognized that some patients with sepsis also develop hemophagocytic lymphocytosis. For decades this was believed to be extremely rare. However, currently there is increasing recognition that this combination might represent a significant fraction of sepsis patients. EMCrit by Josh Farkas. from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1U8TFza
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