Head and Neck Medicine by Alexandros G.Sfakianakis: OtoRhinoLaryngology & Medicine,New Articles,July 26th,2016

Δευτέρα 25 Ιουλίου 2016

OtoRhinoLaryngology & Medicine,New Articles,July 26th,2016

Medical therapy versus sinus surgery by using balloon sinus dilation technology

otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 12 δευτερόλεπτα

A prospective multicenter study: Abstract: Background: Although previous studies of sinus surgery that used balloon catheter dilation technology for the paranasal sinuses (balloon sinus dilation [BSD]) demonstrated safety and efficacy, data that compare BSD with continued medical management (MM) are lacking. Objective: To evaluate the outcomes of sinus surgery when using BSD instruments versus MM […]

Two-stage laparoscopic curative resection for synchronous multiple colorectal cancers: A case report

Gastric volvulus with a large bochdalek hernia in an adult successfully treated with emergency endoscopic reduction followed by elective laparoscopic mesh repair: A case study

Three-dimensional printing of large nasal septal perforations

for optimal prosthetic closure: Abstract: Background: Since 1972, patients with large nasal perforations, who were symptomatic, and who were not candidates for surgery, had the option of custom prosthetic closure at Mayo Clinic. Although septal prostheses have helped many patients, 27% of pre-1982 patients chose not to keep the prosthesis in place. Two-dimensional computed tomography […]

Cerebrospinal fluid rhinorrhea secondary to idiopathic intracranial hypertension

Long-term outcomes of endoscopic repairs: Abstract: Background: Endoscopic endonasal repair of cerebrospinal fluid (CSF) rhinorrhea secondary to idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri or benign intracranial hypertension, has varying success rates, from 25‐87%, with minimal morbidity. However, often these series have a relatively short-term follow-up. Given the pathophysiology of IIH, long-term follow-up […]

Considerations in the management of giant frontal mucoceles with significant intracranial extension

A systematic review: Abstract: Background: Giant frontal mucoceles, characterized by significant intracranial and/or intraorbital extension, can present with significant neurologic symptoms. Although typical mucoceles are managed endoscopically, giant mucoceles are often treated with an open or combined approach due to various concerns, including frontal lobe displacement, size, and rapid decompression of the intracranial component. The […]

A comparison of radiographic evidence of frontal sinusitis in middle-turbinate sacrificing versus middle-turbinate sparing approaches to the sella

A comparison of radiographic evidence of frontal sinusitis in middle-turbinate sacrificing versus middle-turbinate sparing approaches to the sella: Abstract: Background: Initial descriptions of endoscopic approaches to the sella and pituitary involved resecting the middle turbinate (MT) to help improve access and visualization. Modifications of these procedures to preserve the MT have since been described, one […]

Comparison of the aesthetic results of two common incisions in external rhinoplasty: A randomized trial

Comparison of the aesthetic results of two common incisions in external rhinoplasty: A randomized trial: Abstract: Objective: To compare the scar outcomes of two common incisions (inverted V and stair step) by using a validated scar-outcome instrument via a randomized clinical trial. Methods: Fifty-eight consecutive cases of external rhinoplasty were randomly divided into two groups […]

Automated identification of an aspirin-exacerbated respiratory disease cohort

Automated identification of an aspirin-exacerbated respiratory disease cohort: An informatics search algorithm can successfully identify diagnosed and undiagnosed cases of aspirin-exacerbated respiratory disease (AERD) in the electronic health record. Katherine N. Cahill, MD , Christina B. Johns, BA , Jing Cui, MD, PhD , Paige Wickner, MD, MPH , David W. Bates, MD, MSc , […]

Simultaneous Bilateral Hypertrophies of The Parotid Gland and Masseter Muscle

: Case Report via Oral and Maxillofacial Surgery Source:Journal of Oral and Maxillofacial SurgeryAuthor(s): Rohan Prabhu, Louis MandelIncreased salivary demand can lead to enlarged parotid salivary glands, while increased activity of the masseter muscles will cause masseter hypertrophy. The authors report a most unusual case of simultaneous bilateral hypertrophies of the parotid gland and masseter muscle […]

Sleep and sleepiness in environmental intolerances

: a population- based study via Sleep Medicine Publication date: Available online 21 July 2016Source:Sleep MedicineAuthor(s): Maria Nordin, Steven NordinBackgroundAbout one fourth of the general population report environmental intolerance (EI) to odorous/pungent chemicals, certain buildings, electromagnetic fields (EMFs) and/or sounds. EI sufferers show various clinical features, of which sleep disturbance is one. Sleep disturbance is common […]

Diffusion Tensor Imaging and Tractography in Surgery of Brainstem Cavernous Malformations

The Usefulness of via World Neurosurgery Publication date: September 2016Source:World Neurosurgery, Volume 93Author(s): Jacob Januszewski, Lauren Albert, Karen Black, Amir R. DehdashtiBackgroundDiffusion tensor imaging (DTI) estimates the course and connectivity patterns of white matter tracts. The objective of this study is to evaluate whether findings in the brain stem modify the preoperative surgical trajectory planning or […]

Exacerbation of Autoimmune Thyroiditis by CTLA-4 Blockade: A Role for IFNγ-Induced Indoleamine 2, 3-Dioxygenase.CTLA-4 blockade exacerbates the iodine-accelerated form of thyroiditis typical of the NOD-H2h4 mouse. The study could also have implications for cancer patients who develop thyroiditis as an immune-related adverse event after CTLA-4 blockade.

Exacerbation of Autoimmune Thyroiditis by CTLA-4 Blockade: A Role for IFNγ-Induced Indoleamine 2, 3-Dioxygenase: Thyroid , Vol. 0, No. 0. Author information Rajni Sharma,1 Giulia Di Dalmazi,1,2 and Patrizio Caturegli1,3 1Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland. 2Department of Medicine, G. d’Annunzio University of Chieti, Cheti, Italy. 3Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School […]

Iodine Status and Prevalence of Thyroid Disorders

Iodine Status and Prevalence of Thyroid Disorders After Introduction of Mandatory Universal Salt Iodization for 16 Years in China: A Cross-Sectional Study in 10 Cities: Thyroid , Vol. 0, No. 0. Author information Zhongyan Shan,1 Lulu Chen,2 Xiaolan Lian,3 Chao Liu,4 Bingyin Shi,5 Lixin Shi,6 Nanwei Tong,7 Shu Wang,8 Jianping Weng,9 Jiajun Zhao,10 Xiaochun Teng,1 Xiaohui Yu,1 Yaxin Lai,1 Weiwei Wang,1Chenyan Li,1 Jinyuan Mao,1 Yongze Li,1 Chenling Fan,1 and Weiping Teng1 1Department of […]

Incidence of Nonthyroidal Primary Malignancy and the Association with 131I Treatment in Patients with Differentiated Thyroid Cancer

Incidence of Nonthyroidal Primary Malignancy and the Association with 131I Treatment in Patients with Differentiated Thyroid Cancer: Thyroid , Vol. 0, No. 0. Author information Dania Hirsch,1,2 Tzippy Shohat,3 Alex Gorshtein,1,2 Eyal Robenshtok,1,2 Ilan Shimon,1,2 and Carlos Benbassat2,4 1Institute of Endocrinology, Rabin Medical Center–Beilinson Hospital, Petach Tikva, Israel. 2Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. 3Statistics Unit, Rabin Medical Center–Beilinson Hospital, […]

Papillary Thyroid Carcinoma: Germline variants not only predispose to PTC but also might impact its clinical course. However, these associations were only moderate, and further large multi-ethnic studies are required to evaluate the usefulness of these germline variants in the clinical stratification of PTC patients.

Papillary Thyroid Carcinoma: Association Between Germline DNA Variant Markers and Clinical Parameters: Thyroid , Vol. 0, No. 0. Author information Jaroslaw Jendrzejewski,1,4 Sandya Liyanarachchi,1 Rebecca Nagy,1 Leigha Senter,1 Paul E. Wakely,2Andrew Thomas,1 Fadi Nabhan,3 Huiling He,1 Wei Li,1 Krzysztof Sworczak,4 Matthew D. Ringel,3Lawrence S. Kirschner,3 and Albert de la Chapelle1 1Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio. 2Department of Pathology, The Ohio […]

A proposal for a new scoring system to predict difficult ventilation through a supraglottic airway

A proposal for a new scoring system to predict difficult ventilation through a supraglottic airway: Background The aim of this study was to propose and validate a new clinical score to predict difficult ventilation through a supraglottic airway device. Methods The score was proposed from our previously reported derivation data, and we prospectively validated the […]

Severe glucose-6-phosphate dehydrogenase deficiency leads to susceptibility to infection and absent NETosis

Severe glucose-6-phosphate dehydrogenase deficiency leads to susceptibility to infection and absent NETosis: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymatic disorder of red blood cells in human subjects, causing hemolytic anemia linked to impaired nicotinamide adenine dinucleotide phosphate (NADPH) production and imbalanced redox homeostasis in erythrocytes. Because G6PD is expressed by a variety of […]

Automated diagnostic system for tuberculosis

An adoption model describing clinician’s acceptance of automated diagnostic system for tuberculosis: Abstract Computerised medical diagnosing systems are very important to all healthcare professionals, especially clinicians who help in clinical decision-making in complex situations. The acceptance of automated or computerised medical diagnosing system for Tuberculosis (TB) among clinicians is very essential for its effective implementation […]

Esophagogastric junction distensibility identifies achalasia subgroup with manometrically normal esophagogastric junction relaxation

otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 3 ώρες

GABA-producing Bifidobacterium dentium modulates visceral sensitivity in the intestine

otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 3 ώρες

Abstract Background Recurrent abdominal pain is a common and costly health-care problem attributed, in part, to visceral hypersensitivity. Increasing evidence suggests that gut bacteria contribute to abdominal pain perception by modulating the microbiome-gut-brain axis. However, specific microbial signals remain poorly defined. γ-aminobutyric acid (GABA) is a principal inhibitory neurotransmitter and a key regulator of abdominal […]

Anatomy of the Eustachian Tube

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 8 δευτερόλεπτα

The eustachian tube consists of 2 compartments: the Rüdinger's safety canal and the auxiliary gap. It is surrounded by a cartilaginous wall on the craniomedial side and a membranous wall on the inferolateral side. The eustachian tube cartilage is firmly attached to the skull base by the lateral and the medial suspensory ligaments, which are separated by the medial Ostmann fat pad. The function of the isometric tensor veli palatini muscle is modulated by hypomochlia, which have an influence on the muscular force vectors. from #ENT via xlomafota13 on Inoreader http://ift.tt/2a7NayK ... περισσότερα »

Endoscopic Management of Middle Ear and Temporal Bone Lesions

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 8 δευτερόλεπτα

Tantamount to the management of temporal bone neoplasms is the ability to visualize the pathology and its relationship with the numerous critical structures housed therein. Transcanal endoscopic ear surgery provides the surgeon with an unparalleled view of the entire middle ear. This article presents the latest information on the usefulness of transcanal endoscopic ear surgery in the management of middle ear and temporal bone neoplasms. from #ENT via xlomafota13 on Inoreader http://ift.tt/2amEjGk via IFTTT

Endoscopic Facial Nerve Surgery

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 8 δευτερόλεπτα

Tympanic facial nerve segment surgery has been traditionally performed using microscopic approaches, but currently, exclusive endoscopic approaches have been performed for traumatic, neoplastic, or inflammatory diseases, specially located at the geniculate ganglion, greater petrosal nerve, and second tract of the facial nerve, until the second genu. The tympanic segment of the facial nerve can be reached and visualized using an exclusive transcanal endoscopic approach, even in poorly accessible regions such as the second genu and geniculate ganglion, avoiding mastoidectomy, bony d... περισσότερα »

Eustachian Tube Function

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 8 δευτερόλεπτα

The fibrocartilaginous eustachian tube is part of a system of contiguous organs including the nose, palate, rhinopharynx, and middle ear cleft. The middle ear cleft consists of the tympanic cavity, which includes the bony eustachian tube (protympanum) and the mastoid gas cells system. The tympanic cavity and mastoid gas cells are interconnected and allow gaseous exchange and pressure regulation. The fibrocartilaginous eustachian tube is a complex organ consisting of a dynamic conduit with its mucosa, cartilage, surrounding soft tissue, peritubal muscles (ie, tensor and levator veli... περισσότερα »

Preoperative and Intraoperative Evaluation of the Eustachian Tube in Chronic Ear Surgery

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 8 δευτερόλεπτα

This article discusses the authors' approach to the assessment of the eustachian tube using opening pressure measurement, endoscopic assessment of the protympanic segment of the eustachian tube, and Valsalva computed tomography. A possible algorithm for the evaluation of eustachian tube obstructive disorders is detailed both preoperatively and intraoperatively. from #ENT via xlomafota13 on Inoreader http://ift.tt/2a7NhdZ via IFTTT

Transnasal Endoscopic Eustachian Tube Surgery

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 8 δευτερόλεπτα

The purpose of this article is to give a contemporary review of transnasal endoscopic surgery for Eustachian tube disorders. The authors' perspective of the relevant anatomy, pathophysiology, and evaluation of Eustachian tube disorders as related to surgical intervention also is provided. from #ENT via xlomafota13 on Inoreader http://ift.tt/2amE2TN via IFTTT

Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα

• Evening reading on a tablet for 2 hours did not alter saliva melatonin levels.• Sleepiness, sleep onset latency, as well as sleep composition remained unaffected.• Tablet reading did not impact power spectral density during slow-wave sleep. from #ENT via xlomafota13 on Inoreader http://ift.tt/2aaW9MT via IFTTT

Abnormal thyroid hormones and non-thyroidal illness syndrome in obstructive sleep apnea, and effects of CPAP treatment

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα

• Non-thyroidal illness syndrome (NTIS) occurred in obstructive sleep apnea (OSA)• NTIS in OSA was associated with severe nocturnal hypoxemia• Low T3 could reduce nocturnal energy expenditure in the most hypoxemic OSA subjects• Free T3 was normalised after CPAP treatment in OSA patients with NTIS• TSH slightly increased after CPAP treatment in subclinically hypothyroid OSA subjects from #ENT via xlomafota13 on Inoreader http://ift.tt/2a9YLY9 via IFTTT

Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα

Abnormal thyroid hormones and non-thyroidal illness syndrome in obstructive sleep apnea, and effects of CPAP treatment

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα

Familial Central Hypothyroidism Caused by a Novel IGSF1 Gene Mutation

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα

Thyroid , Vol. 0, No. 0. from #ENT via xlomafota13 on Inoreader http://ift.tt/2a5YlnJ via IFTTT

Effect of Thyroid Function Variations Within the Laboratory Reference Range on Health Status, Mood, and Cognition in Levothyroxine-Treated Subjects

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα

[image: access_no.gif] Thyroid , Vol. 0, No. 0. from #ENT via xlomafota13 on Inoreader http://ift.tt/2a5Y7gs via IFTTT

Spine Stereotactic Radiosurgery for Patients with Metastatic Thyroid Cancer: Secondary Analysis of Phase I/II Trials

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα

[image: access_no.gif] Thyroid , Vol. 0, No. 0. from #ENT via xlomafota13 on Inoreader http://ift.tt/2acPkI5 via IFTTT

Familial Central Hypothyroidism Caused by a Novel IGSF1 Gene Mutation

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Thyroid , Vol. 0, No. 0. from #ENT via xlomafota13 on Inoreader http://ift.tt/2a5YlnJ via IFTTT

Effect of Thyroid Function Variations Within the Laboratory Reference Range on Health Status, Mood, and Cognition in Levothyroxine-Treated Subjects

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

[image: access_no.gif] Thyroid , Vol. 0, No. 0. from #ENT via xlomafota13 on Inoreader http://ift.tt/2a5Y7gs via IFTTT

Spine Stereotactic Radiosurgery for Patients with Metastatic Thyroid Cancer: Secondary Analysis of Phase I/II Trials

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

[image: access_no.gif] Thyroid , Vol. 0, No. 0. from #ENT via xlomafota13 on Inoreader http://ift.tt/2acPkI5 via IFTTT

IL-4 and IL-15 promotion of virtual memory CD8+ T cells is determined by genetic background

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Virtual memory (VM) CD8+ T cells, which are present in unimmunized mice, yet possess T-cell receptors specific for foreign antigens. To date, VM cells have only been characterized in C57BL/6 mice. Here, we assessed the cytokine requirements for VM cells in C57BL/6 and BALB/c mice. As reported previously, VM cells in C57BL/6 mice rely mostly on IL-15 and marginally on IL-4. In stark contrast, VM cells in BALB/c mice rely substantially on IL-4 and marginally on IL-15. Further, NKT cells are the likely source of IL-4, because CD1d-deficient mice on a BALB/c background have significan... περισσότερα »

IL-4 and IL-15 promotion of virtual memory CD8+ T cells is determined by genetic background

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

The Osteosarcoradionecrosis as an Unfavorable Result Following Head and Neck Tumor Ablation and Microsurgical Reconstruction

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Publication date: Available online 25 July 2016 *Source:*Clinics in Plastic Surgery Author(s): Nidal Farhan AL Deek, Fu-Chan Wei Teaser Osteoradionecrosis is preferably called osteosarcoradionecrosis to adequately cover the scope of the problem: multitissue necrosis. The changes following radiotherapy and leading to necrosis are further classified into 2 phases based on improved understanding of the underlying mechanisms. The reversible-damage phase could respond to the medical treatment, while the irreversible damage phase or osteosarcoradionecrosis may benefit from complete resec... περισσότερα »

The Osteosarcoradionecrosis as an Unfavorable Result Following Head and Neck Tumor Ablation and Microsurgical Reconstruction

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Minimal Margin Extracapsular Dissection: A Viable Alternative Technique for Benign Parotid Lesions?

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα

Objective: Extracapsular dissection (ECD) has become an accepted, less invasive alternative for the removal of select benign parotid lesions that may reduce complications. Minimal margin extracapsular dissection (MECD) with dissection on or closer to the tumor capsule may be a reasonable alternative to ECD. The objective of this study is to review the complications and safety of the MECD technique at a single institution. Subjects and Methods: Medical records for patients who underwent MECD for suspected benign parotid lesions were reviewed. Outcome measurements included intraop... περισσότερα »

Minimal Margin Extracapsular Dissection: A Viable Alternative Technique for Benign Parotid Lesions?

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 2 ώρες

Esophagogastric junction distensibility identifies achalasia subgroup with manometrically normal esophagogastric junction relaxation

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

Abstract Background Manometric criteria to diagnose achalasia are absent peristalsis and incomplete relaxation of the esophagogastric junction (EGJ), determined by an integrated relaxation pressure (IRP) >15 mm Hg. However, EGJ relaxation seems normal in a subgroup of patients with typical symptoms of achalasia, no endoscopic abnormalities, stasis on timed barium esophagogram (TBE), and absent peristalsis on high-resolution manometry (HRM). The aim of our study was to further characterize these patients by measuring EGJ distensibility and assessing the effect of achalasia treatmen... περισσότερα »

GABA-producing Bifidobacterium dentium modulates visceral sensitivity in the intestine

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

Abstract Background Recurrent abdominal pain is a common and costly health-care problem attributed, in part, to visceral hypersensitivity. Increasing evidence suggests that gut bacteria contribute to abdominal pain perception by modulating the microbiome-gut-brain axis. However, specific microbial signals remain poorly defined. *γ*-aminobutyric acid (GABA) is a principal inhibitory neurotransmitter and a key regulator of abdominal and central pain perception from peripheral afferent neurons. Although gut bacteria are reported to produce GABA, it is not known whether the microbial-... περισσότερα »

Contralateral Prophylactic Mastectomy: Higher Complication Rates

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

Women undergoing contralateral prophylactic mastectomy (CPM) and reconstruction have more post-op complications than those who choose unilateral surgery, but they also report more satisfaction with their new breasts, new research reports. *Reuters Health Information* from #ENT via xlomafota13 on Inoreader http://ift.tt/2a9nPhW via IFTTT

Computed Tomography Angiography Allows the Classification of the First Dorsal Metatarsal Arteries

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

J reconstr Microsurg DOI: 10.1055/s-0036-1585464 Background Conventional angiography is an invasive technique. Submillimeter computed tomography angiography (CTA) has been shown to be an effective alternative for peripheral artery branches. This study aimed to assess the use of CTA to guide the choice and design of foot donor area for finger or thumb reconstruction. Methods This was a retrospective study of 79 patients who underwent finger or thumb reconstruction between January, 2011 and March, 2014. All these patients underwent preoperative CTA to determine the exact blood suppl... περισσότερα »

Preliminary Exploration: When Angiosome Meets Prefabricated Flaps

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

J reconstr Microsurg DOI: 10.1055/s-0036-1585468 Background The best known limitation to the use of prefabricated flaps is their limited survival area. One explanation for this is insufficient neovascularization. However, blood flow of prefabricated flaps is through their innate vascular network. This could lead one to conclude that angiosomes may impede blood perfusion. This study aims to settle this contradiction between theory and clinical practice. Methods We performed a two-stage operation of a prefabricated abdominal flap in a rat model. The rats were divided into five group... περισσότερα »

Esophagogastric junction distensibility identifies achalasia subgroup with manometrically normal esophagogastric junction relaxation

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

GABA-producing Bifidobacterium dentium modulates visceral sensitivity in the intestine

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

Abstract Background Recurrent abdominal pain is a common and costly health-care problem attributed, in part, to visceral hypersensitivity. Increasing evidence suggests that gut bacteria contribute to abdominal pain perception by modulating the microbiome-gut-brain axis. However, specific microbial signals remain poorly defined. *γ*-aminobutyric acid (GABA) is a principal inhibitory neurotransmitter and a key regulator of abdominal and central pain perception from peripheral afferent neurons. Although gut bacteria are reported to produce GABA, it is not known whether the microbial-... περισσότερα »

Contralateral Prophylactic Mastectomy: Higher Complication Rates

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

Computed Tomography Angiography Allows the Classification of the First Dorsal Metatarsal Arteries

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

Preliminary Exploration: When Angiosome Meets Prefabricated Flaps

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

The Rolling Fingers Test

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

J reconstr Microsurg DOI: 10.1055/s-0036-1584952 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA. Article in Thieme eJournals: Table of contents | Full text from #ENT via xlomafota13 on Inoreader http://ift.tt/2aalpmm via IFTTT

Assessing worldwide research activity on probiotics in pediatrics using Scopus database: 1994–2014

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

A wide variety of probiotic products has been introduced into the market in the past decade. Research trends and activity on probiotics help understand how these products were evolved and their potential futur... from #ENT via xlomafota13 on Inoreader http://ift.tt/2a5tJmp via IFTTT

Der Freiburger Einsilbertest auf dem Prüfstand

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

from #ENT via xlomafota13 on Inoreader http://ift.tt/2affGwL via IFTTT

Numerische Strömungssimulation

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

Zusammenfassung Die gegenwärtigen Möglichkeiten zur objektiven Beurteilung der Nasenatmung sind begrenzt. Sie beschränken sich auf die Bestimmung des Gesamtwiderstands der Nase. Aussagen über die endonasalen Strömungsverhältnisse können nicht getroffen werden. Die Methode der numerischen Strömungssimulation ist dagegen in der Lage, Detailinformationen des Strömungsfelds innerhalb der Nasenhöhle zu gewinnen. Sie hat das Potenzial, die Nasenströmung umfassend und patientenindividuell zu analysieren. Die Voraussetzung ist lediglich eine Computertomographie der Nasennebenhöhlen. Dem k... περισσότερα »

A preliminary study of the oral microbiota in Chinese patients with Sjögren’s syndrome

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

[image: S00039969.gif] Publication date: October 2016 *Source:*Archives of Oral Biology, Volume 70 Author(s): Miaoran Li, Yan Zou, Qian Jiang, Lindi Jiang, Qiang Yu, Xiaojun Ding, Youcheng Yu ObjectiveTo investigate the oral microbiota in Sjögren's syndrome (SS) as opposed to that of healthy subjects.Study designTen patients with primary SS, [6 patients daily taking stable dosage of hydroxychloroquine (HC) and 4 patients taking hydroxychloroquine combined with Prednisone acetas (HC+PA)], along with 10 age-matched healthy controls were examined in regard of number of teeth, stimulate... περισσότερα »

Lysine-specific proteolytic activity responsible for forsythia detaching factor modification

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

[image: alertIcon.gif] Publication date: November 2016 *Source:*Archives of Oral Biology, Volume 71 Author(s): Hidetomo Onishi, Munehiko Ro, Takafumi Suzuki, Makiko Ishii, Hideharu Otsuka, Kazuhiro Yatabe, Joichiro Hayashi, Junichi Tatsumi, Kitetsu Shin ObjectivesThe objective of the present study was to clarify the lysine-specific proteolytic activity derived from periodontal pathogens responsible for Forsythia detaching factor (FDF) modification.DesignThe activity responsible for FDF modification in Tannerella forsythia and Porphyromonas gingivalis were evaluated by colorimetric a... περισσότερα »

Growth hormone positive effects on craniofacial complex in Turner syndrome

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

[image: S00039969.gif] Publication date: November 2016 *Source:*Archives of Oral Biology, Volume 71 Author(s): Jovana Juloski, Jelena Dumančić, Ivana Šćepan, Tomislav Lauc, Jelena Milašin, Zvonimir Kaić, Miroslav Dumić, Marko Babić ObjectiveTurner syndrome occurs in phenotypic females with complete or partial absence of X chromosome. The leading symptom is short stature, while numerous but mild stigmata manifest in the craniofacial region. These patients are commonly treated with growth hormone to improve their final height. The aim of this study was to assess the influence of long-t... περισσότερα »

The role of food stiffness in dental microwear feature formation

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

[image: S00039969.gif] Publication date: November 2016 *Source:*Archives of Oral Biology, Volume 71 Author(s): David J. Daegling, Li-Cheng Hua, Peter S. Ungar ObjectiveThe etiology of dental microwear is incompletely understood, despite copious documentation of wear patterns from wild and captive specimens across numerous vertebrate taxa. Among the contested issues with respect to microwear formation is the question of whether materials softer than enamel (specifically, foods themselves) can produce wear features.DesignWe examine the creation of enamel microwear features in vitro fr... περισσότερα »

High-fluoride acitivates the FasL signalling pathway and leads to damage of ameloblast ultrastructure

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 4 ώρες

[image: S00039969.gif] Publication date: November 2016 *Source:*Archives of Oral Biology, Volume 71 Author(s): Lin Wang, Yong Zhu, Danyang Wang ObjectiveHigh fluoride can induce stress-mediated apoptosis and degradation of ameloblasts. Fas ligand (FasL) has been regarded as a key regulator in intracellular responses for stress-induced apoptosis in reproductive or cancerous cell lineages. The objective of this study is to explore the role of FasL in the regulation of ameloblast ultrastructure damage.DesignPrimary ameloblasts were isolated from the molar tooth germ of 4-day-old SD rats... περισσότερα »

Smad2 overexpression induces alveolar bone loss and up regulates TNF-α, and RANKL

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 4 ώρες

[image: S00039969.gif] Publication date: November 2016 *Source:*Archives of Oral Biology, Volume 71 Author(s): Mazen K. Alotaibi, Yukiko Kitase, Charles F. Shuler ObjectiveThe aim of the current study was to investigate whether Smad2 overexpression in JE cells induced alveolar bone loss, and to understand the mechanisms regulating the bone loss.MethodsA mouse line was created that used a cytokeratin 14 (K14) promoter to overexpress Smad2 in the epithelium of the transgenic mice (K14-Smad2). Micro CT radiographs (μCT) were used to assess bone loss, bone volume, and bone density. The ... περισσότερα »

Tongue implant for assistive technologies: Test of migration, tissue reactivity and impact on tongue function

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 4 ώρες

[image: S00039969.gif] Publication date: November 2016 *Source:*Archives of Oral Biology, Volume 71 Author(s): Sylive Mimche, Dukju Ahn, Mehdi Kiani, Hassan Elahi, Kyle Murray, Kirk Easley, Alan Sokoloff, Maysam Ghovanloo ObjectiveThe Tongue Drive System (TDS) is a new wearable assistive technology (AT), developed to translate voluntary tongue movements to user-defined computer commands by tracking the position of a titanium-encased magnetic tracer (Ti-Mag) implanted into the tongue. TDS application, however, is constrained by limited information on biological consequence and safety... περισσότερα »

Smad2 overexpression enhances adhesion of gingival epithelial cells

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 4 ώρες

[image: S00039969.gif] Publication date: November 2016 *Source:*Archives of Oral Biology, Volume 71 Author(s): Shoichi Hongo, Tadashi Yamamoto, Keisuke Yamashiro, Masayuki Shimoe, Kazuya Tomikawa, Yuki Ugawa, Shinsuke Kochi, Hidetaka Ideguchi, Hiroshi Maeda, Shogo Takashiba ObjectiveGingival epithelial cells play an important role in preventing the initiation of periodontitis, by their hemidesmosomal adhesion to the tooth root surface. Adhesion requires integrin-extracellular matrix (ECM) interactions that are intricately regulated by transforming growth factor-β (TGF-β) signaling. ... περισσότερα »

Matrix-Gla Protein rs4236 [A/G] gene polymorphism and serum and GCF levels of MGP in patients with subgingival dental calculus

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 4 ώρες

[image: S00039969.gif] Publication date: October 2016 *Source:*Archives of Oral Biology, Volume 70 Author(s): Gülnihal Emrem Doğan, Turgut Demir, Hülya Aksoy, Ebru Sağlam, Esra Laloğlu, Abdulkadir Yildirim AimMatrix-Gla Protein (MGP) is one of the major Gla-containing protein associated with calcification process. It also has a high affinity for Ca2+ and hydroxyapatite. In this study we aimed to evaluate the MGP rs4236 [A/G] gene polymorphism in association with subgingival dental calculus. Also a possible relationship between MGP gene polymorphism and serum and GCF levels of MGP we... περισσότερα »

Evaluation of inflammation during fixed orthodontic treatment

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 4 ώρες

[image: S00039969.gif] Publication date: November 2016 *Source:*Archives of Oral Biology, Volume 71 Author(s): Fundagul Bilgic, Ozlem Akinci Sozer, Oguzhan Ozcan, Ahmet Burak Gurpinar, Hakki Yilmaz, Yazgi Ay ObjectiveThe aim of this study was to assess effects of fixed orthodontic therapy on high-sensitivity C-reactive protein (hs-CRP) level, CBC parameters and levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT), gamma glutamyl transferase (GGT), alkaline phosphatase (ALP), urea, creatinine, sodium (Na), potassium (K), calcium (Ca), total protein (TP), and ... περισσότερα »

Dental pulp cells promote the expression of receptor activator of nuclear factor-κB ligand, prostaglandin E2 and substance P in mechanically stressed periodontal ligament cells

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 4 ώρες

Publication date: October 2016 *Source:*Archives of Oral Biology, Volume 70 Author(s): Taiki Morikawa, Kenichi Matsuzaka, Kei Nakajima, Toshihiko Yasumura, Kenji Sueishi, Takashi Inoue ObjectiveThis study investigated the expression of receptor activator of nuclear factor-κB ligand (RANKL) in periodontal ligament (PDL) cells co-cultured with dental pulp (DP) cells following mechanical stress in vitro. Furthermore, the expression of prostaglandin (PG) E2 and substance P (SP) by the PDL cells and by the DP cells were also examined.DesignPDL and DP cells were obtained from 10 rats. The... περισσότερα »

Assessing worldwide research activity on probiotics in pediatrics using Scopus database: 1994–2014

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 5 ώρες

Der Freiburger Einsilbertest auf dem Prüfstand

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 5 ώρες

from #ENT via xlomafota13 on Inoreader http://ift.tt/2affGwL via IFTTT

Numerische Strömungssimulation

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 5 ώρες

Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 5 δευτερόλεπτα

Publication date: Available online 25 July 2016 *Source:*Sleep Medicine Author(s): Frida H. Rångtell, Emelie Ekstrand, Linnea Rapp, Anna Lagermalm, Lisanne Liethof, Marcela Olaya Búcaro, David Lingfors, Jan-Erik Broman, Helgi B. Schiöth, Christian Benedict BackgroundThe use of electronical devices emitting blue light during evening hours has been associated with sleep disturbances in humans, possibly due to the blue light-mediated suppression of the sleep-promoting hormone melatonin. However, experimental results have been mixed. The present study therefore sought to investigate if ... περισσότερα »

Abnormal thyroid hormones and non-thyroidal illness syndrome in obstructive sleep apnea, and effects of CPAP treatment

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 5 δευτερόλεπτα

[image: S13899457.gif] Publication date: Available online 25 July 2016 *Source:*Sleep Medicine Author(s): Albino Petrone, Flaminio Mormile, Giacomo Bruni, Michela Quartieri, Maria R. Bonsignore, Oreste Marrone ObjectiveWhile the influences of both hypothyroidism and hyperthyroidism on obstructive sleep apnea (OSA) have been studied, the occurrence of non-thyroidal illness syndrome (NTIS) (normal thyroid stimulating hormone (TSH) with low triiodotironine) has not been investigated. We explored the occurrence of NTIS in patients with moderate to severe OSA and its relationship to the ... περισσότερα »

Large-scale population screening for prodromal PD: a way forward becomes clear

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 5 δευτερόλεπτα

[image: alertIcon.gif] Publication date: Available online 25 July 2016 *Source:*Sleep Medicine Author(s): Ronald B. Postuma, Jacques Y Montplaisir from #SleepMedicine via xlomafota13 on Inoreader http://ift.tt/2apSFXX via IFTTT

Two-stage laparoscopic curative resection for synchronous multiple colorectal cancers: A case report

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 5 δευτερόλεπτα

Abstract A 75-year-old man tested positive for occult blood in the stool. A subsequent examination indicated concurrent locally advanced cancer (cT3) at the hepatic flexure and lower rectum cancer in the external anal sphincter. Because of the locally advanced rectal cancer (cT4), preoperative chemoradiotherapy was administered. First, laparoscopic right hemicolectomy and colostomy were performed at the sigmoid colon. Chemoradiotherapy for rectal cancer was initiated on day 18 after the surgeries. Seven weeks after chemoradiotherapy had been completed, laparoscopic abdominoperinea... περισσότερα »

Gastric volvulus with a large bochdalek hernia in an adult successfully treated with emergency endoscopic reduction followed by elective laparoscopic mesh repair: A case study

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 5 δευτερόλεπτα

Abstract We report a case of gastric volvulus with a large Bochdalek hernia successfully treated with emergency endoscopic reduction followed by elective laparoscopic mesh repair. The patient was a 71-year-old woman with no history of trauma. She was referred to our hospital because of nausea and vomiting after eating. Thoracic and abdominal CT showed gastric volvulus and a large Bochdalek hernia. The patient underwent emergency endoscopic reduction and elective laparoscopic surgery. The defect (10 × 12 cm) was reinforced with a Dual Mesh (expanded polytetrafluoroethylene) and fix... περισσότερα »

Two hours of evening reading on a self-luminous tablet vs. reading a physical book does not alter sleep after daytime bright light exposure

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 51 δευτερόλεπτα

• Evening reading on a tablet for 2 hours did not alter saliva melatonin levels.• Sleepiness, sleep onset latency, as well as sleep composition remained unaffected.• Tablet reading did not impact power spectral density during slow-wave sleep. from #SleepMedicine via xlomafota13 on Inoreader http://ift.tt/2aaW9MT via IFTTT

Abnormal thyroid hormones and non-thyroidal illness syndrome in obstructive sleep apnea, and effects of CPAP treatment

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 51 δευτερόλεπτα

• Non-thyroidal illness syndrome (NTIS) occurred in obstructive sleep apnea (OSA)• NTIS in OSA was associated with severe nocturnal hypoxemia• Low T3 could reduce nocturnal energy expenditure in the most hypoxemic OSA subjects• Free T3 was normalised after CPAP treatment in OSA patients with NTIS• TSH slightly increased after CPAP treatment in subclinically hypothyroid OSA subjects from #SleepMedicine via xlomafota13 on Inoreader http://ift.tt/2a9YLY9 via IFTTT

Esophagogastric junction distensibility identifies achalasia subgroup with manometrically normal esophagogastric junction relaxation

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

GABA-producing Bifidobacterium dentium modulates visceral sensitivity in the intestine

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 3 ώρες

Abstract Background Recurrent abdominal pain is a common and costly health-care problem attributed, in part, to visceral hypersensitivity. Increasing evidence suggests that gut bacteria contribute to abdominal pain perception by modulating the microbiome-gut-brain axis. However, specific microbial signals remain poorly defined. *γ*-aminobutyric acid (GABA) is a principal inhibitory neurotransmitter and a key regulator of abdominal and central pain perception from peripheral afferent neurons. Although gut bacteria are reported to produce GABA, it is not known whether the microbial-... περισσότερα »

Eustachian Tube Function

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

Preoperative and Intraoperative Evaluation of the Eustachian Tube in Chronic Ear Surgery

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

Transnasal Endoscopic Eustachian Tube Surgery

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

Stabilization of the Craniovertebral Junction with Clivus Plate Constructs: Biomechanical Comparison with Conventional Technique

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

[image: S18788750.gif] Publication date: October 2016 *Source:*World Neurosurgery, Volume 94 Author(s): Wei Ji, Jie Tong, Zhiping Huang, Minghui Zheng, Xiuhua Wu, Jianting Chen, Qingan Zhu BackgroundVentral defect caused by resection of the lesions involving the upper cervical spine commonly has been reconstructed with a fabricated mesh cage. Recently, a clival screw and plate fitted to the osseous anatomy of the craniovertebral junction was developed for this pathologic status.ObjectiveTo evaluate the stability a clivus plate system fixation (CPSF) for the craniovertebral junction ... περισσότερα »

Lumbar Neuroforaminal Decompression with a Flexible Microblade Shaver System: Results of a Cadaveric Study

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

[image: S18788750.gif] Publication date: October 2016 *Source:*World Neurosurgery, Volume 94 Author(s): Lennart Viezens, Marc Dreimann, Roland Gessler, Martin Stangenberg, Sven Oliver Eicker BackgroundThe lumbar neural foraminal stenosis still is a challenging condition in minimally invasive spine surgery. Because of the anatomic situation a complete decompression of the nerve root often leads to a subtotal facetectomy associated with potential instability and the need for additional instrumentation of the decompressed segment. The iO-Flex system was introduced to address this probl... περισσότερα »

Management Outcome of Brainstem Arteriovenous Malformations: The Role of Radiosurgery

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

[image: S18788750.gif] Publication date: October 2016 *Source:*World Neurosurgery, Volume 94 Author(s): Wuyang Yang, Jose L. Porras, Tomas Garzon-Muvdi, Risheng Xu, Justin M. Caplan, Alice L. Hung, Maria Braileanu, Xiaoming Rong, Geoffrey P. Colby, Alexander L. Coon, Rafael J. Tamargo, Judy Huang IntroductionManagement decisions for brainstem arteriovenous malformations (AVMs) are complicated by balancing the risks of treatment and natural progression to hemorrhage. The present study seeks to compare radiosurgery and conservative management outcomes in brainstem AVMs.MethodsWe perfor... περισσότερα »

Treatment Strategies to Attenuate Perihematomal Edema in Patients With Intracerebral Hemorrhage

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

[image: S18788750.gif] Publication date: October 2016 *Source:*World Neurosurgery, Volume 94 Author(s): Hoon Kim, Nancy J. Edwards, Huimahn A. Choi, Tiffany R. Chang, Kwang Wook Jo, Kiwon Lee Spontaneous intracerebral hemorrhage (SICH) continues to be a significant cause of neurologic morbidity and mortality throughout the world. Although recent advances in the treatment of SICH have significantly decreased mortality rates, functional recovery has not been dramatically improved by any intervention to date. There are 2 predominant mechanisms of brain injury from intracerebral hemorrh... περισσότερα »

Microvascular Decompression for Trigeminal Neuralgia: Technical Refinement for Complication Avoidance

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

[image: S18788750.gif] Publication date: October 2016 *Source:*World Neurosurgery, Volume 94 Author(s): Francesco Tomasello, Felice Esposito, Rosaria V. Abbritti, Filippo F. Angileri, Alfredo Conti, Salvatore M. Cardali, Domenico La Torre BackgroundMicrovascular decompression (MVD) represents the most effective and safe surgical option for the treatment of trigeminal neuralgia since it was first popularized by Jannetta 50 years ago. Despite several advances, complications such as cerebellar and vascular injury, hearing loss, muscular atrophy, cerebrospinal fluid (CSF) leak, postopera... περισσότερα »

Gamma Knife Surgery for Cavernous Sinus Hemanginoma: A Report of 32 Cases

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

[image: S18788750.gif] Publication date: October 2016 *Source:*World Neurosurgery, Volume 94 Author(s): Yi Wang, Peng Li, Xin J. Zhang, Yang Y. Xu, Wei Wang BackgroundCavernous sinus hemangioma (CSH) is a rare type of benign vascular tumor. Microsurgery for CSH treatment usually results in profuse bleeding and cranial nerve injury. Radiosurgery is an alternative treatment for CSH. The objective of this study was to elucidate the efficacy and safety of gamma knife surgery (GKS) for the treatment of CSH.MethodsA total of 32 patients with CSH underwent 34 times of GKS as a primary and ... περισσότερα »

Role of Intraoperative Neurophysiologic Monitoring in the Resection of Thalamic Astrocytomas

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

[image: S18788750.gif] Publication date: October 2016 *Source:*World Neurosurgery, Volume 94 Author(s): Giorgio Carrabba, Giulio Bertani, Filippo Cogiamanian, Gianluca Ardolino, Barbara Zarino, Andrea Di Cristofori, Marco Locatelli, Manuela Caroli, Paolo Rampini BackgroundThe thalamus is a deep-seated and crucial structure for the sensorimotor system. It has been long considered a surgically inaccessible area because of the morbidity associated with surgical resections. Astrocytomas of the thalamus are usually treated with bioptic procedures followed by adjuvant treatments. Intraope... περισσότερα »

Effects of aging on P300 between late young-age and early middle-age adulthood: an electroencephalogram event-related potential study.

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

The aim of this study was to identify age-related changes of P300 peak amplitude and P300 latency between closely separated nonsenile age groups (late young-aged adults and early middle-aged adults) and to investigate whether or not P300 has the potential to be used as a measure of cognitive aging even among nonsenile age groups. Twenty-eight adults (25-55 years old) completed an event-related potential oddball task. The elicitation of both P300 peak amplitude and P300 latency indicated age-related changes of P300. The results of the study showed that the P300 target peak amplitude ... περισσότερα »

Individual variability in verbal fluency correlates with [gamma]-aminobutyric acid concentration in the left inferior frontal gyrus.

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

A particular feature of the inferior frontal gyrus (IFG), which is considered a central region for language processing, is leftward functional/anatomical asymmetry. However, previous studies have not clearly shown lateralization of neurotransmitters in the cortical regions. Using proton magnetic resonance spectroscopy, we measured [gamma]-aminobutyric acid (GABA) concentrations in the bilateral IFG. To evaluate individual variability in linguistic performance, we further used a verbal fluency test. Although GABA+/creatine (Cr) values were not different between the left and the right... περισσότερα »

The glucagon-like peptide-1 analog exendin-4 antagonizes the effect of acyl ghrelin on the respiratory exchange ratio.

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 δευτερόλεπτα

The present study investigated the interaction of hypothalamic arcuate nucleus (ArcN) ghrelin and glucagon-like peptide-1 (GLP-1) signaling on metabolic function. Using indirect calorimetry, we first showed that acylated ghrelin, administered into the ArcN, significantly increased the respiratory exchange ratio (RER) in male Sprague-Dawley rats, representing a shift in fuel utilization toward enhanced carbohydrate oxidation and reduced lipid utilization. In contrast, treatment with similar doses of des-acyl ghrelin failed to induce reliable changes in RER. We then examined the abili... περισσότερα »