Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Κυριακή 10 Ιουλίου 2016

OtoRhinoLaryngology & Medicine,New Articles,July 11th,2016


CDH11 inhibits proliferation and invasion in head and neck cancer

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 λεπτό
[image: cover.gif?v=1&s=fa071a998e1fff64ddf228a0] Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression in HNSCC was evaluated by immunohistochemistry on a tissue microarray (TMA) and immunoblotting and immunofluorescence of cell lines. The functional impact of CDH11 on prolifera... περισσότερα »

CDH11 inhibits proliferation and invasion in head and neck cancer

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 λεπτό
[image: cover.gif?v=1&s=fa071a998e1fff64ddf228a0] Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression in HNSCC was evaluated by immunohistochemistry on a tissue microarray (TMA) and immunoblotting and immunofluorescence of cell lines. The functional impact of CDH11 on prolifera... περισσότερα »

Leukemia

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 13 δευτερόλεπτα
Leukemia: Cancer of the blood cells. Strictly speaking, leukemia should refer only to cancer of the white blood cells (leukocytes), but in practice it can apply to malignancy of any cellular element in the blood or bone marrow, as in red cell leukemia (erythroleukemia). Treatment may involve chemo’therapy, radiation therapy, biological therapy, and/or bone marrow… Continue reading Leukemia

Leukemia

Leukemia: Cancer of the blood cells. Strictly speaking, leukemia should refer only to cancer of the white blood cells (leukocytes), but in practice it can apply to malignancy of any cellular element in the blood or bone marrow, as in red cell leukemia (erythroleukemia). Treatment may involve chemo’therapy, radiation therapy, biological therapy, and/or bone marrow […]

Reality Training: Severe head wound behind home plate

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
How would you treat a baseball umpire's significant head laceration as players, fans and television viewers watch your every move? from EMS via xlomafota13 on Inoreader http://ift.tt/29xLdsm

Reality Training: Severe head wound behind home plate

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
*Incident Date:* June 23, 2016 *Department:* Athletic trainers and Paramedics Plus, the standby medical service for the Oakland A's *What happened:* Home plate umpire Paul Emmel was hit in the head when Angels’ pinch-hitter Jefry Marte lost control of his bat. Emmel immediately fell to the ground. When he removed his hat, blood cascaded into the sand. The sound of the bat hitting Emmel's head was startling to players, and the blood streaming out of a laceration was surely just as frightening for television viewers. Read more about the incident and watch the video of the injury. ... περισσότερα »

Prediction of Post-interventional Outcome in Great Saphenous Vein Incompetence: The Role of Venous Plethysmography with Selective Superficial Vein Occlusion

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Publication date: Available online 9 July 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): POE. Nelzén, J. Skoog, C. Lassvik, T. Länne, H. Zachrisson Objective/BackgroundTo evaluate whether the outcome of radiofrequency ablation (RFA) treatment of great saphenous vein (GSV) incompetence may be predicted using strain-gauge plethysmography (SGP) with selective occlusion of the superficial venous system.MethodsSeventeen patients (20 limbs) underwent endovenous RFA treatment for GSV incompetence (Clinical Etiology Anatomy Pathophysiology classification C2–C5... περισσότερα »

Prediction of Post-interventional Outcome in Great Saphenous Vein Incompetence: The Role of Venous Plethysmography with Selective Superficial Vein Occlusion

Publication date: Available online 9 July 2016 Source:European Journal of Vascular and Endovascular Surgery Author(s): POE. Nelzén, J. Skoog, C. Lassvik, T. Länne, H. Zachrisson Objective/BackgroundTo evaluate whether the outcome of radiofrequency ablation (RFA) treatment of great saphenous vein (GSV) incompetence may be predicted using strain-gauge plethysmography (SGP) with selective occlusion of the superficial venous […]

Emergence and maintenance of excitability: kinetics over structure

Publication date: October 2016 Source:Current Opinion in Neurobiology, Volume 40 Author(s): Shimon Marom The capacity to generate action potentials in neurons and other excitable cells requires tuning of both ionic channel expression and kinetics in a large parameter space. Alongside studies that extend traditional focus on control-based regulation of structural parameters (channel densities), there is […]

When brain rhythms aren’t ‘rhythmic’: implication for their mechanisms and meaning

Publication date: October 2016 Source:Current Opinion in Neurobiology, Volume 40 Author(s): Stephanie R Jones Rhythms are a prominent signature of brain activity. Their expression is correlated with numerous examples of healthy information processing and their fluctuations are a marker of disease states. Yet, their causal or epiphenomenal role in brain function is still highly debated. […]

CDH11 inhibits proliferation and invasion in head and neck cancer

Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression […]

Prediction of Post-interventional Outcome in Great Saphenous Vein Incompetence: The Role of Venous Plethysmography with Selective Superficial Vein Occlusion

Alexandros G. SfakianakisστοΕνδοκρινολογίαΠριν από 35 δευτερόλεπτα
Publication date: Available online 9 July 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): POE. Nelzén, J. Skoog, C. Lassvik, T. Länne, H. Zachrisson Objective/BackgroundTo evaluate whether the outcome of radiofrequency ablation (RFA) treatment of great saphenous vein (GSV) incompetence may be predicted using strain-gauge plethysmography (SGP) with selective occlusion of the superficial venous system.MethodsSeventeen patients (20 limbs) underwent endovenous RFA treatment for GSV incompetence (Clinical Etiology Anatomy Pathophysiology classification C2–C5... περισσότερα »

Effects of Ionizing Radiation on the Heart

AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 46 δευτερόλεπτα
Publication date: Available online 10 July 2016 *Source:*Mutation Research/Reviews in Mutation Research Author(s): Marjan Boerma, Vijayalakshmi Sridharan, Xiao-Wen Mao, Gregory A. Nelson, Amrita K. Cheema, Igor Koturbash, Sharda P. Singh, Alan J. Tackett, Martin Hauer-Jensen This article provides an overview of studies addressing effects of ionizing radiation on the heart. Clinical studies have identified early and late manifestations of radiation-induced heart disease, a side effect of radiation therapy to tumors in the chest when all or part of the heart is situated in the radiati... περισσότερα »

Emergence and maintenance of excitability: kinetics over structure

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 52 δευτερόλεπτα
[image: S09594388.gif] Publication date: October 2016 *Source:*Current Opinion in Neurobiology, Volume 40 Author(s): Shimon Marom The capacity to generate action potentials in neurons and other excitable cells requires tuning of both ionic channel expression and kinetics in a large parameter space. Alongside studies that extend traditional focus on control-based regulation of structural parameters (channel densities), there is a budding interest in self-organization of kinetic parameters. In this picture, ionic channels are continually forced by activity in-and-out of a pool of stat... περισσότερα »

When brain rhythms aren't ‘rhythmic’: implication for their mechanisms and meaning

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 52 δευτερόλεπτα
[image: S09594388.gif] Publication date: October 2016 *Source:*Current Opinion in Neurobiology, Volume 40 Author(s): Stephanie R Jones Rhythms are a prominent signature of brain activity. Their expression is correlated with numerous examples of healthy information processing and their fluctuations are a marker of disease states. Yet, their causal or epiphenomenal role in brain function is still highly debated. We review recent studies showing brain rhythms are not always 'rhythmic', by which we mean representative of repeated cycles of activity. Rather, high power and continuous rhy... περισσότερα »

RESEARCH ON MIDWIFERY STUDENT’S ETHICAL SUSCEPTIBILITY ON PATIENT CARE PRACTICES

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 52 δευτερόλεπτα
2016-07-10T18-38-49Z *Source:* Journal of Contemporary Medicine Yasemin AYDIN, Yurdanur Dikmen, Sare Cansu Kalkan. Objective: Objective of this research is examining last grade students ethical susceptibility includes their susceptibility towards ethics, ethical codes and ethical dilemmas who are candidates to midwifery profession. Method: The research which is planned as descriptive one was carried out with intern students who study at Health College Midwifery Department of a public university between January-February 2016. Sample of the research contains 52 volunteer students. Quest... περισσότερα »

CDH11 inhibits proliferation and invasion in head and neck cancer

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 56 δευτερόλεπτα
[image: cover.gif?v=1&s=fa071a998e1fff64ddf228a0] Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression in HNSCC was evaluated by immunohistochemistry on a tissue microarray (TMA) and immunoblotting and immunofluorescence of cell lines. The functional impact of CDH11 on proliferati... περισσότερα »

Emergence and maintenance of excitability: kinetics over structure

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα
[image: S09594388.gif] Publication date: October 2016 *Source:*Current Opinion in Neurobiology, Volume 40 Author(s): Shimon Marom The capacity to generate action potentials in neurons and other excitable cells requires tuning of both ionic channel expression and kinetics in a large parameter space. Alongside studies that extend traditional focus on control-based regulation of structural parameters (channel densities), there is a budding interest in self-organization of kinetic parameters. In this picture, ionic channels are continually forced by activity in-and-out of a pool of stat... περισσότερα »

When brain rhythms aren't ‘rhythmic’: implication for their mechanisms and meaning

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα
[image: S09594388.gif] Publication date: October 2016 *Source:*Current Opinion in Neurobiology, Volume 40 Author(s): Stephanie R Jones Rhythms are a prominent signature of brain activity. Their expression is correlated with numerous examples of healthy information processing and their fluctuations are a marker of disease states. Yet, their causal or epiphenomenal role in brain function is still highly debated. We review recent studies showing brain rhythms are not always 'rhythmic', by which we mean representative of repeated cycles of activity. Rather, high power and continuous rhy... περισσότερα »

CDH11 inhibits proliferation and invasion in head and neck cancer

Alexandros G. SfakianakisστοHead and Neck DiseasesΠριν από 57 δευτερόλεπτα
[image: cover.gif?v=1&s=fa071a998e1fff64ddf228a0] Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression in HNSCC was evaluated by immunohistochemistry on a tissue microarray (TMA) and immunoblotting and immunofluorescence of cell lines. The functional impact of CDH11 on prolifera... περισσότερα »

Integrin β4 is a major target antigen in pure ocular mucous membrane pemphigoid

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Abstract Background Previous studies of ocular mucous membrane pemphigoid (OMMP) have identified several components of the basement membrane zone to be autoantigens, including integrin β4. However, there are no extensive or definitive reported studies that address this, particularly in pure OMMP. Objectives To clarify the major autoantigens in pure OMMP. Materials and methods In this study, we examined sera from 43 pure OMMP patients for both IgG and IgA antibodies using newly developed immunoblotting analyses with a hemidesmosome-rich fraction and various recombinant proteins of... περισσότερα »

Hair and nail adverse events during treatment with targeted therapies for metastatic melanoma

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
Abstract Background Targeted therapies for melanoma have shown clinical benefit in increasing the survival of metastatic patients. Cutaneous adverse events have been reported, but hair and nail data have been rarely detailed. Materials and methods Patients treated with BRAF andMEKinhibitors for metastatic melanoma underwent dermatological evaluation before the start of each treatment and after every four weeks. Pull test, global photography, dermoscopy/trichoscopy and scalp biopsy were performed. Appendages adverse events were graded using the National Cancer Institute's Common Te... περισσότερα »

Novel nonsense mutation of the TSC2 gene in a case of tuberous sclerosis complex

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/29yj1EI via IFTTT

Erythema papulosa semicircularis recidivans associated with primary pancreas B cell lymphoma

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 1 ώρα
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/29wYzYH via IFTTT

CDH11 inhibits proliferation and invasion in head and neck cancer

Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression […]

Effects of organic acids and initial solution pH on photocatalytic degradation of bisphenol A (BPA) in a photo-Fenton-like process using Goethite (small alpha-FeOOH)

Photochem. Photobiol. Sci., 2016, Accepted Manuscript DOI: 10.1039/C6PP00051G, Paper Guangshan Zhang, Qiao Wang, Wen Zhang, Tian Li, Yixing Yuan, Peng Wang This work investigated the effects of organic acids and initial solution pH on the photodegradation of BPA in a photo-Fenton-like process using [small alpha]-FeOOH as a catalyst. The results showed that… The content of […]

Farewell to life on land – thoracic strength as a new indicator to determine paleoecology in secondary aquatic mammals

Abstract Habitat shifts from land to water have occurred independently in several mammal lineages. However, because we do not know completely about the relationship between skeletal morphology and function, both reliable life reconstructions of each extinct taxon and the timing of those shifts in locomotor strategies are yet to be fully understood. We estimated the […]

Proportions of blood-borne Vδ1+ and Vδ2+ T-cells are associated with overall survival of melanoma patien ts treated with ipilimumab

Publication date: September 2016 Source:European Journal of Cancer, Volume 64 Author(s): Kilian Wistuba-Hamprecht, Alexander Martens, Karin Haehnel, Marnix Geukes Foppen, Jianda Yuan, Michael A. Postow, Phillip Wong, Emanuela Romano, Amir Khammari, Brigitte Dreno, Mariaelena Capone, Paolo A. Ascierto, Ilja Demuth, Elisabeth Steinhagen-Thiessen, Anis Larbi, Bastian Schilling, Dirk Schadendorf, Jedd D. Wolchok, Christian U. Blank, Graham […]

CDH11 inhibits proliferation and invasion in head and neck cancer

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: cover.gif?v=1&s=fa071a998e1fff64ddf228a0] Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression in HNSCC was evaluated by immunohistochemistry on a tissue microarray (TMA) and immunoblotting and immunofluorescence of cell lines. The functional impact of CDH11 on prolifera... περισσότερα »

CDH11 inhibits proliferation and invasion in head and neck cancer

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression… Continue reading CDH11 inhibits proliferation and invasion in head and neck cancer

CDH11 inhibits proliferation and invasion in head and neck cancer

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression… Continue reading CDH11 inhibits proliferation and invasion in head and neck cancer

Effects of organic acids and initial solution pH on photocatalytic degradation of bisphenol A (BPA) in a photo-Fenton-like process using Goethite (small alpha-FeOOH)

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Photochem. Photobiol. Sci., 2016, Accepted Manuscript DOI: 10.1039/C6PP00051G, Paper Guangshan Zhang, Qiao Wang, Wen Zhang, Tian Li, Yixing Yuan, Peng Wang This work investigated the effects of organic acids and initial solution pH on the photodegradation of BPA in a photo-Fenton-like process using [small alpha]-FeOOH as a catalyst. The results showed that… The content of… Continue reading Effects of organic acids and initial solution pH on photocatalytic degradation of bisphenol A (BPA) in a photo-Fenton-like process using Goethite (small alpha-FeOOH)

CDH11 inhibits proliferation and invasion in head and neck cancer

Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression […]

Addition of sodium criterion to SOAR stroke score

Objectives To examine the usefulness of including sodium (Na) levels as a criterion to the SOAR stroke score in predicting inpatient and 7-day mortality in stroke. Materials and Methods Data from the Norfolk and Norwich University Hospital Stroke & TIA register (2003–2015) were analysed. Univariate and then multivariate models controlling for SOAR variables were used […]

Unfavorable Results After Free Tissue Transfer to Head and Neck

Publication date: Available online 9 July 2016Source:Clinics in Plastic Surgery Author(s): Marika Kuuskeri, Anne C. O’Neill, Stefan O.P. Hofer Teaser The purpose of the current article is to provide an overview of the functional and aesthetic unfavorable results of head and neck reconstruction, and provide suggestions on how to address these issues. Understanding the consequences […]

CDH11 inhibits proliferation and invasion in head and neck cancer

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: cover.gif?v=1&s=fa071a998e1fff64ddf228a0] Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression in HNSCC was evaluated by immunohistochemistry on a tissue microarray (TMA) and immunoblotting and immunofluorescence of cell lines. The functional impact of CDH11 on prolifera... περισσότερα »

Unfavorable Results After Free Tissue Transfer to Head and Neck

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 9 July 2016 *Source:*Clinics in Plastic Surgery Author(s): Marika Kuuskeri, Anne C. O'Neill, Stefan O.P. Hofer Teaser The purpose of the current article is to provide an overview of the functional and aesthetic unfavorable results of head and neck reconstruction, and provide suggestions on how to address these issues. Understanding the consequences of an unsuccessful reconstruction provides the foundation for proper planning and personalized approach to reconstruction of lost structures. from #ENT via xlomafota13 on Inoreader http://ift.tt/29NZra... περισσότερα »

Unfavorable Results After Free Tissue Transfer to Head and Neck

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 9 July 2016 *Source:*Clinics in Plastic Surgery Author(s): Marika Kuuskeri, Anne C. O'Neill, Stefan O.P. Hofer Teaser The purpose of the current article is to provide an overview of the functional and aesthetic unfavorable results of head and neck reconstruction, and provide suggestions on how to address these issues. Understanding the consequences of an unsuccessful reconstruction provides the foundation for proper planning and personalized approach to reconstruction of lost structures. from #ENT via xlomafota13 on Inoreader http://ift.tt/29NZra... περισσότερα »

Unfavorable Results After Free Tissue Transfer to Head and Neck

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 9 July 2016 *Source:*Clinics in Plastic Surgery Author(s): Marika Kuuskeri, Anne C. O'Neill, Stefan O.P. Hofer Teaser The purpose of the current article is to provide an overview of the functional and aesthetic unfavorable results of head and neck reconstruction, and provide suggestions on how to address these issues. Understanding the consequences of an unsuccessful reconstruction provides the foundation for proper planning and personalized approach to reconstruction of lost structures. from #ENT via xlomafota13 on Inoreader http://ift.tt/29NZra... περισσότερα »

Risk factors for periprosthetic joint infection following primary total hip or knee arthroplasty: a meta-analysis

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract To identify risk factors for periprosthetic joint infection following primary total joint arthroplasty, a systematic search was performed in Pubmed, Embase and Cochrane library databases. Pooled odds ratios (ORs) or standardised mean differences (SMDs) with 95% confidence intervals (CIs) were calculated. Patient characteristics, surgical-related factors and comorbidities, as potential risk factors, were investigated. The main factors associated with infection after total joint arthroplasty (TJA) were male gender (OR, 1·48; 95% CI, 1.19–1.85), age (SMD, −0·10; 95% CI, −0.1... περισσότερα »

Relationship between maceration and wound healing on diabetic foot ulcers in Indonesia: a prospective study

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract The aim of this study was to clarify the relationship between maceration and wound healing. A prospective longitudinal design was used in this study. The wound condition determined the type of dressings used and the dressing change frequency. A total of 62 participants with diabetic foot ulcers (70 wounds) were divided into two groups: non-macerated (*n* = 52) and macerated wounds (*n* = 18). Each group was evaluated weekly using the Bates–Jensen Wound Assessment Tool, with follow-ups until week 4. The Mann–Whitney *U* test showed that the changes in the wound area in week... περισσότερα »

Risk factors for periprosthetic joint infection following primary total hip or knee arthroplasty: a meta-analysis

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract To identify risk factors for periprosthetic joint infection following primary total joint arthroplasty, a systematic search was performed in Pubmed, Embase and Cochrane library databases. Pooled odds ratios (ORs) or standardised mean differences (SMDs) with 95% confidence intervals (CIs) were calculated. Patient characteristics, surgical-related factors and comorbidities, as potential risk factors, were investigated. The main factors associated with infection after total joint arthroplasty (TJA) were male gender (OR, 1·48; 95% CI, 1.19–1.85), age (SMD, −0·10; 95% CI, −0.1... περισσότερα »

Relationship between maceration and wound healing on diabetic foot ulcers in Indonesia: a prospective study

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract The aim of this study was to clarify the relationship between maceration and wound healing. A prospective longitudinal design was used in this study. The wound condition determined the type of dressings used and the dressing change frequency. A total of 62 participants with diabetic foot ulcers (70 wounds) were divided into two groups: non-macerated (*n* = 52) and macerated wounds (*n* = 18). Each group was evaluated weekly using the Bates–Jensen Wound Assessment Tool, with follow-ups until week 4. The Mann–Whitney *U* test showed that the changes in the wound area in week... περισσότερα »

CDH11 inhibits proliferation and invasion in head and neck cancer

Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression […]

CDH11 inhibits proliferation and invasion in head and neck cancer

Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 1 ώρα
[image: cover.gif?v=1&s=fa071a998e1fff64ddf228a0] Background In this study, we use a bioinformatics-based strategy to nominate a tumor suppressor gene cadherin-11 (CDH11) and investigate its role in growth and invasion in head and neck squamous cell carcinoma (HNSCC). Methods Using the Oncomine™ database to compare HNSCC and normal specimens, CDH11 was nominated as having a role in HNSCC. CDH11 expression in HNSCC was evaluated by immunohistochemistry on a tissue microarray (TMA) and immunoblotting and immunofluorescence of cell lines. The functional impact of CDH11 on prolifera... περισσότερα »

Addition of sodium criterion to SOAR stroke score

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
Objectives To examine the usefulness of including sodium (Na) levels as a criterion to the SOAR stroke score in predicting inpatient and 7-day mortality in stroke. Materials and Methods Data from the Norfolk and Norwich University Hospital Stroke & TIA register (2003–2015) were analysed. Univariate and then multivariate models controlling for SOAR variables were used to assess the association between admission sodium levels and inpatient and 7-day mortality. The prognostic ability of the SOAR and SOAR Na scores for mortality outcomes at both time points were then compared using t... περισσότερα »

Unfavorable Results After Free Tissue Transfer to Head and Neck

Alexandros G. SfakianakisστοHead and Neck DiseasesΠριν από 2 ώρες
Publication date: Available online 9 July 2016 *Source:*Clinics in Plastic Surgery Author(s): Marika Kuuskeri, Anne C. O'Neill, Stefan O.P. Hofer Teaser The purpose of the current article is to provide an overview of the functional and aesthetic unfavorable results of head and neck reconstruction, and provide suggestions on how to address these issues. Understanding the consequences of an unsuccessful reconstruction provides the foundation for proper planning and personalized approach to reconstruction of lost structures. http://ift.tt/29NZraK http://ift.tt/29wTaRl OtoRhinoLaryng... περισσότερα »

Addition of sodium criterion to SOAR stroke score

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 2 ώρες
Objectives To examine the usefulness of including sodium (Na) levels as a criterion to the SOAR stroke score in predicting inpatient and 7-day mortality in stroke. Materials and Methods Data from the Norfolk and Norwich University Hospital Stroke & TIA register (2003–2015) were analysed. Univariate and then multivariate models controlling for SOAR variables were used to assess the association between admission sodium levels and inpatient and 7-day mortality. The prognostic ability of the SOAR and SOAR Na scores for mortality outcomes at both time points were then compared using t... περισσότερα »

Unfavorable Results After Free Tissue Transfer to Head and Neck

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 2 ώρες
Publication date: Available online 9 July 2016 *Source:*Clinics in Plastic Surgery Author(s): Marika Kuuskeri, Anne C. O’Neill, Stefan O.P. Hofer Teaser The purpose of the current article is to provide an overview of the functional and aesthetic unfavorable results of head and neck reconstruction, and provide suggestions on how to address these issues. Understanding the consequences of an unsuccessful reconstruction provides the foundation for proper planning and personalized approach to reconstruction of lost structures. http://ift.tt/29NZraK

Reality Training: Severe head wound behind home plate

How would you treat a baseball umpire's significant head laceration as players, fans and television viewers watch your every move? from EMS via xlomafota13 on Inoreader http://ift.tt/29xLdsm via IFTTT

Design of complex adaptive multiresolution directional filter bank and application to pansharpening

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 2 ώρες
Abstract This paper proposes a new 2-D transform design, namely *complex adaptive multiresolution directional filter bank*, to represent the spatial orientation features of an input image *adaptively*. The proposed design is completely *shift invariant* and represents the input image by one low-pass and multiscale *N* directional band-pass subbands. Here, *N* represents estimated number of dominant directions present in the input image. Our design consists of two main filter bank stages. A fix partitioned complex-valued directional filter bank (CDFB) is at the core of the design f... περισσότερα »

Unfavorable Results After Free Tissue Transfer to Head and Neck

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 2 ώρες
Publication date: Available online 9 July 2016 *Source:*Clinics in Plastic Surgery Author(s): Marika Kuuskeri, Anne C. O'Neill, Stefan O.P. Hofer Teaser The purpose of the current article is to provide an overview of the functional and aesthetic unfavorable results of head and neck reconstruction, and provide suggestions on how to address these issues. Understanding the consequences of an unsuccessful reconstruction provides the foundation for proper planning and personalized approach to reconstruction of lost structures. http://ift.tt/29NZraK

Risk factors for periprosthetic joint infection following primary total hip or knee arthroplasty: a meta-analysis

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 2 ώρες
Abstract To identify risk factors for periprosthetic joint infection following primary total joint arthroplasty, a systematic search was performed in Pubmed, Embase and Cochrane library databases. Pooled odds ratios (ORs) or standardised mean differences (SMDs) with 95% confidence intervals (CIs) were calculated. Patient characteristics, surgical-related factors and comorbidities, as potential risk factors, were investigated. The main factors associated with infection after total joint arthroplasty (TJA) were male gender (OR, 1·48; 95% CI, 1.19–1.85), age (SMD, −0·10; 95% CI, −0.1... περισσότερα »

Relationship between maceration and wound healing on diabetic foot ulcers in Indonesia: a prospective study

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 2 ώρες
Abstract The aim of this study was to clarify the relationship between maceration and wound healing. A prospective longitudinal design was used in this study. The wound condition determined the type of dressings used and the dressing change frequency. A total of 62 participants with diabetic foot ulcers (70 wounds) were divided into two groups: non-macerated (*n* = 52) and macerated wounds (*n* = 18). Each group was evaluated weekly using the Bates–Jensen Wound Assessment Tool, with follow-ups until week 4. The Mann–Whitney *U* test showed that the changes in the wound area in week... περισσότερα »

Does family background impact driving attitudes and risky behaviours? An investigation on Chinese young drivers

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 ώρες
Publication date: October 2016 Source:Accident Analysis & Prevention, Volume 95, Part A Author(s): Zhe Wang, Zuduo Zheng, Judy J. Fleiter The rapid pace of motorisation in China has been well documented, as has the large road trauma burden the Chinese citizens are facing as a result. China’s unique political system represents an important consideration in… Continue reading Does family background impact driving attitudes and risky behaviours? An investigation on Chinese young drivers

The effect of a road safety educational program for kindergarten children on their parents’ behavior and knowledge

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 ώρες
Publication date: October 2016 Source:Accident Analysis & Prevention, Volume 95, Part A Author(s): Tamar Ben-Bassat, Shani Avnieli Road safety education for children is one of the most important means for raising awareness of road safety and for educating children to behave safely as pedestrians, bicycle riders, and vehicle passengers. The current research presents a novel… Continue reading The effect of a road safety educational program for kindergarten children on their parents’ behavior and knowledge

Proportions of blood-borne Vδ1+ and Vδ2+ T-cells are associated with overall survival of melanoma patients treated with ipilimumab

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 2 ώρες
Publication date: September 2016 *Source:*European Journal of Cancer, Volume 64 Author(s): Kilian Wistuba-Hamprecht, Alexander Martens, Karin Haehnel, Marnix Geukes Foppen, Jianda Yuan, Michael A. Postow, Phillip Wong, Emanuela Romano, Amir Khammari, Brigitte Dreno, Mariaelena Capone, Paolo A. Ascierto, Ilja Demuth, Elisabeth Steinhagen-Thiessen, Anis Larbi, Bastian Schilling, Dirk Schadendorf, Jedd D. Wolchok, Christian U. Blank, Graham Pawelec, Claus Garbe, Benjamin Weide Human γδ T-cells possess regulatory and cytotoxic capabilities, and could potentially influence the efficacy of ... περισσότερα »

Unfavorable Results After Free Tissue Transfer to Head and Neck

Publication date: Available online 9 July 2016 Source:Clinics in Plastic Surgery Author(s): Marika Kuuskeri, Anne C. O’Neill, Stefan O.P. Hofer Teaser The purpose of the current article is to provide an overview of the functional and aesthetic unfavorable results of head and neck reconstruction, and provide suggestions on how to address these issues. Understanding the […]

Risk factors for periprosthetic joint infection following primary total hip or knee arthroplasty: a meta-analysis

Abstract To identify risk factors for periprosthetic joint infection following primary total joint arthroplasty, a systematic search was performed in Pubmed, Embase and Cochrane library databases. Pooled odds ratios (ORs) or standardised mean differences (SMDs) with 95% confidence intervals (CIs) were calculated. Patient characteristics, surgical-related factors and comorbidities, as potential risk factors, were investigated. The […]

Relationship between maceration and wound healing on diabetic foot ulcers in Indonesia: a prospective study

Abstract The aim of this study was to clarify the relationship between maceration and wound healing. A prospective longitudinal design was used in this study. The wound condition determined the type of dressings used and the dressing change frequency. A total of 62 participants with diabetic foot ulcers (70 wounds) were divided into two groups: […]

Does family background impact driving attitudes and risky behaviours? An investigation on Chinese young drivers

Publication date: October 2016 Source:Accident Analysis & Prevention, Volume 95, Part A Author(s): Zhe Wang, Zuduo Zheng, Judy J. Fleiter The rapid pace of motorisation in China has been well documented, as has the large road trauma burden the Chinese citizens are facing as a result. China’s unique political system represents an important consideration in […]

The effect of a road safety educational program for kindergarten children on their parents’ behavior and knowledge

Publication date: October 2016 Source:Accident Analysis & Prevention, Volume 95, Part A Author(s): Tamar Ben-Bassat, Shani Avnieli Road safety education for children is one of the most important means for raising awareness of road safety and for educating children to behave safely as pedestrians, bicycle riders, and vehicle passengers. The current research presents a novel […]

Reality Training: Severe head wound behind home plate

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
*Incident Date:* June 23, 2016 *Department:* Athletic trainers and Paramedics Plus, the standby medical service for the Oakland A's *What happened:* Home plate umpire Paul Emmel was hit in the head when Angels’ pinch-hitter Jefry Marte lost control of his bat. Emmel immediately fell to the ground. When he removed his hat, blood cascaded into the sand. The sound of the bat hitting Emmel's head was startling to players, and the blood streaming out of a laceration was surely just as frightening for television viewers. Read more about the incident and watch the video of the injury. ... περισσότερα »

Risk factors for periprosthetic joint infection following primary total hip or knee arthroplasty: a meta-analysis

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 2 ώρες
Abstract To identify risk factors for periprosthetic joint infection following primary total joint arthroplasty, a systematic search was performed in Pubmed, Embase and Cochrane library databases. Pooled odds ratios (ORs) or standardised mean differences (SMDs) with 95% confidence intervals (CIs) were calculated. Patient characteristics, surgical-related factors and comorbidities, as potential risk factors, were investigated. The main factors associated with infection after total joint arthroplasty (TJA) were male gender (OR, 1·48; 95% CI, 1.19–1.85), age (SMD, −0·10; 95% CI, −0.1... περισσότερα »

Relationship between maceration and wound healing on diabetic foot ulcers in Indonesia: a prospective study

Alexandros G. SfakianakisστοΑισθητική ΔερματολογίαΠριν από 2 ώρες
Abstract The aim of this study was to clarify the relationship between maceration and wound healing. A prospective longitudinal design was used in this study. The wound condition determined the type of dressings used and the dressing change frequency. A total of 62 participants with diabetic foot ulcers (70 wounds) were divided into two groups: non-macerated (*n* = 52) and macerated wounds (*n* = 18). Each group was evaluated weekly using the Bates–Jensen Wound Assessment Tool, with follow-ups until week 4. The Mann–Whitney *U* test showed that the changes in the wound area in week... περισσότερα »

Risk factors for periprosthetic joint infection following primary total hip or knee arthroplasty: a meta-analysis

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 2 ώρες
Abstract To identify risk factors for periprosthetic joint infection following primary total joint arthroplasty, a systematic search was performed in Pubmed, Embase and Cochrane library databases. Pooled odds ratios (ORs) or standardised mean differences (SMDs) with 95% confidence intervals (CIs) were calculated. Patient characteristics, surgical-related factors and comorbidities, as potential risk factors, were investigated. The main factors associated with infection after total joint arthroplasty (TJA) were male gender (OR, 1·48; 95% CI, 1.19–1.85), age (SMD, −0·10; 95% CI, −0.1... περισσότερα »

Relationship between maceration and wound healing on diabetic foot ulcers in Indonesia: a prospective study

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 2 ώρες
Abstract The aim of this study was to clarify the relationship between maceration and wound healing. A prospective longitudinal design was used in this study. The wound condition determined the type of dressings used and the dressing change frequency. A total of 62 participants with diabetic foot ulcers (70 wounds) were divided into two groups: non-macerated (*n* = 52) and macerated wounds (*n* = 18). Each group was evaluated weekly using the Bates–Jensen Wound Assessment Tool, with follow-ups until week 4. The Mann–Whitney *U* test showed that the changes in the wound area in week... περισσότερα »

Farewell to life on land – thoracic strength as a new indicator to determine paleoecology in secondary aquatic mammals

Abstract Habitat shifts from land to water have occurred independently in several mammal lineages. However, because we do not know completely about the relationship between skeletal morphology and function, both reliable life reconstructions of each extinct taxon and the timing of those shifts in locomotor strategies are yet to be fully understood. We estimated the […]

Farewell to life on land – thoracic strength as a new indicator to determine paleoecology in secondary aquatic mammals

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 ώρες
Abstract Habitat shifts from land to water have occurred independently in several mammal lineages. However, because we do not know completely about the relationship between skeletal morphology and function, both reliable life reconstructions of each extinct taxon and the timing of those shifts in locomotor strategies are yet to be fully understood. We estimated the strengths of rib cages against vertical compression in 26 extant and four extinct mammal specimens including cetartiodactyls, paenungulates, and carnivorans, representing 11 terrestrial, six semi-aquatic, and nine oblig... περισσότερα »

Farewell to life on land – thoracic strength as a new indicator to determine paleoecology in secondary aquatic mammals

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 3 ώρες
Abstract Habitat shifts from land to water have occurred independently in several mammal lineages. However, because we do not know completely about the relationship between skeletal morphology and function, both reliable life reconstructions of each extinct taxon and the timing of those shifts in locomotor strategies are yet to be fully understood. We estimated the… Continue reading Farewell to life on land – thoracic strength as a new indicator to determine paleoecology in secondary aquatic mammals

A regularized full reference tissue model for PET neuroreceptor mapping

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 3 ώρες
Publication date: 1 October 2016 Source:NeuroImage, Volume 139 Author(s): Joseph B. Mandeville, Christin Y.M. Sander, Hsiao-Ying Wey, Jacob M. Hooker, Hanne D. Hansen, Claus Svarer, Gitte M. Knudsen, Bruce R. Rosen The full reference tissue model (FRTM) is a PET analysis framework that includes both free and specifically bound compartments within tissues, together with rate… Continue reading A regularized full reference tissue model for PET neuroreceptor mapping

Bayesian electromagnetic spatio-temporal imaging of extended sources with Markov Random Field and temporal basis expansion

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 3 ώρες
Publication date: 1 October 2016 Source:NeuroImage, Volume 139 Author(s): Ke Liu, Zhu Liang Yu, Wei Wu, Zhenghui Gu, Yuanqing Li, Srikantan Nagarajan Estimating the locations and spatial extents of brain sources poses a long-standing challenge for electroencephalography and magnetoencephalography (E/MEG) source imaging. In the present work, a novel source imaging method, Bayesian Electromagnetic Spatio-Temporal Imaging… Continue reading Bayesian electromagnetic spatio-temporal imaging of extended sources with Markov Random Field and temporal basis expansion

Effects of aging on low luminance contrast processing in humans

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 3 ώρες
Publication date: 1 October 2016 Source:NeuroImage, Volume 139 Author(s): Emmanuelle Bellot, Véronique Coizet, Jan Warnking, Kenneth Knoblauch, Elena Moro, Michel Dojat Luminance contrast is a fundamental visual cue. Using a dedicated neuroimaging framework, we sought to characterize typical Blood Oxygen Level Dependent (BOLD) responses in two subcortical regions, the superior colliculus (SC) and the lateral… Continue reading Effects of aging on low luminance contrast processing in humans

Reality Training: Severe head wound behind home plate

*Incident Date:* June 23, 2016 *Department:* Athletic trainers and Paramedics Plus, the standby medical service for the Oakland A's *What happened:* Home plate umpire Paul Emmel was hit in the head when Angels' pinch-hitter Jefry Marte lost control of his bat. Emmel immediately fell to the ground. When he removed his hat, blood cascaded into the sand. The sound of the bat hitting Emmel's head was startling to players, and the blood streaming out of a laceration was surely just as frightening for television viewers. Read more about the incident and watch the video of the injury. ... περισσότερα »

Farewell to life on land – thoracic strength as a new indicator to determine paleoecology in secondary aquatic mammals

Abstract Habitat shifts from land to water have occurred independently in several mammal lineages. However, because we do not know completely about the relationship between skeletal morphology and function, both reliable life reconstructions of each extinct taxon and the timing of those shifts in locomotor strategies are yet to be fully understood. We estimated the […]

Farewell to life on land – thoracic strength as a new indicator to determine paleoecology in secondary aquatic mammals

Abstract Habitat shifts from land to water have occurred independently in several mammal lineages. However, because we do not know completely about the relationship between skeletal morphology and function, both reliable life reconstructions of each extinct taxon and the timing of those shifts in locomotor strategies are yet to be fully understood. We estimated the […]

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