Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τετάρτη 10 Αυγούστου 2016

OtoRhinoLaryngology & Medicine,New Articles,August 10th,2016,afternoon


Head and Neck Cancers by Alexandros G. Sfakianakis
A microdeletion at Xq22.2 implicates a glycine receptor GLRA4 involved in intellectual disability, behavioral problems and craniofacial anomalies
Among the 21 annotated genes at Xq22.2, PLP1 is the only known gene involved in Xq22.2 microdeletion and microduplication syndromes with intellectual disability. Using an atypical microdeletion, which does not en... http://ift.tt/2aFLFCK
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
The Influence of Ethanolic Extract of Brazilian Green Propolis Gel on Hygiene and Oral Microbiota in Patients after Mandible Fractures
Maintenance of proper oral hygiene by dental plaque elimination is one of the most important factors affecting the healing process in postoperative oral wounds. Propolis is a substance produced by bees. Ethanolic extract of propolis has bactericidal, fungicidal, anti-inflammatory, and antioxidative properties....
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
The Effect of Neurobehavioral Test Performance on the All-Cause Mortality among US Population
Evidence of the association between global cognitive function and mortality is much, but whether specific cognitive function is related to mortality is unclear. To address the paucity of knowledge on younger populations in the US, we analyzed the association between specific cognitive function and mortality...
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolao
Percutaneous Pedicle Screw Fixation with Polymethylmethacrylate Augmentation for the Treatment of Thoracolumbar Intravertebral Pseudoarthrosis Associated with Kummell’s Osteonecrosis
Purpose. The purpose of our study is to evaluate the therapeutic efficacy of short-segment percutaneous pedicle screw fixation with polymethylmethacrylate (PMMA) augmentation for the treatment of osteoporotic thoracolumbar compression fracture with osteonecrosis. Methods. Osteoporotic thoracolumbar compression...
Θεραπεία
Olaparib for Maintenance Treatment of BRCA 1 or 2 Mutated, Relapsed, Platinum-Sensitive Ovarian, Fallopian Tube and Peritoneal Cancer in People Whose Relapsed Disease has Responded to Platinum-Based Chemotherapy: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
Abstract As part of its Single Technology Appraisal process, the National Institute for Health and Care Excellence (NICE) invited the manufacturer of olaparib (AstraZeneca) to submit evidence on the clinical and cost effectiveness of olaparib for the maintenance treatment of BRCA1/2 mutated (BRCAm),...
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Usage of personal music players in adolescents and its association with noise-induced hearing loss: A cross-sectional analysis of Ohrkan cohort study data
. from #ENT via xlomafota13 on Inoreader http://ift.tt/2aVe6wM via IFTTT
OtoRhinoLaryngology by Alexandros G.Sfakianakis
Estimating audiometric thresholds using simultaneous acquisition of ASSR and ABR from QASSR in patients with sensorineural hearing loss
. from #ENT via xlomafota13 on Inoreader http://ift.tt/2biwLDQ via IFTTT
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer
Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer: Abstract Background The purpose of this study was to investigate the effects of combining the phosphotidylinositol-3-kinase (PI3K)...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
DNA-PkCS expression in oropharyngeal squamous cell carcinoma: Correlations with human papillomavirus status and recurrence after transoral robotic surgery
DNA-PkCS expression in oropharyngeal squamous cell carcinoma: Correlations with human papillomavirus status and recurrence after transoral robotic surgery: Abstract Background Human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (SCC) has improved clinical outcomes compared...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer
Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer: Abstract Background This study is an evaluation of survival in patients with upper aerodigestive tract (UADT) cancer who did not receive guideline-directed therapy. Methods The National Cancer Institute’s...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Predisposing factors for poor prognosis of angiosarcoma of the scalp and face: Systematic review and meta-analysis
Predisposing factors for poor prognosis of angiosarcoma of the scalp and face: Systematic review and meta-analysis: ABSTRACT Background Angiosarcoma of the scalp and face is an aggressive tumor with a high rate of local recurrence. Although many previous studies have demonstrated risk factors for...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Radiotherapy in early-stage tongue squamous cell carcinoma with minor adverse features
Radiotherapy in early-stage tongue squamous cell carcinoma with minor adverse features: Abstract Background Treatment for early-stage tongue squamous cell carcinoma (SCC) is usually surgery alone. There is ambiguity regarding the impact of minor adverse features (MAFs) on outcome and the role of...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Impact of chemotherapy on the outcome of osteosarcoma of the head and neck in adults
Impact of chemotherapy on the outcome of osteosarcoma of the head and neck in adults: Abstract Background There is an ongoing debate about the value of (neo-)adjuvant chemotherapy in high- and intermediate-grade osteosarcoma of the head and neck. Methods All records of patients older than...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Improvement in symptoms of obstructive sleep apnoea in children following tonsillectomy versus tonsillotomy: a systematic review and meta-analysis
Improvement in symptoms of obstructive sleep apnoea in children following tonsillectomy versus tonsillotomy: a systematic review and meta-analysis: Abstract Background Tonsillotomy (or intracapsular tonsillectomy) is a modern technique which is seen by some as potentially superior to traditional...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Comparison of the Motor Performance and Vestibular Function in Infants with a Congenital Cytomegalovirus Infection or a Connexin 26 Mutation: A Preliminary Study.
Comparison of the Motor Performance and Vestibular Function in Infants with a Congenital Cytomegalovirus Infection or a Connexin 26 Mutation: A Preliminary Study.: Objectives: Hearing-impaired children are at risk for vestibular damage and delayed motor development. Two major causes of congenital...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Infant Cortical Auditory Evoked Potentials to Lateralized Noise Shifts Produced by Changes in Interaural Time Difference.
Infant Cortical Auditory Evoked Potentials to Lateralized Noise Shifts Produced by Changes in Interaural Time Difference.: Objectives: Newborns reliably orient to sound location soon after birth; by age 1 month this orienting disappears until after age 4 months. It has been suggested that orienting...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
The Effectiveness and Long-Term Outcome of Conjunctivodacryocystorhinostomy With Frosted Jones Tubes.
The Effectiveness and Long-Term Outcome of Conjunctivodacryocystorhinostomy With Frosted Jones Tubes.: Purpose: To describe success rates and long-term outcomes of conjunctivodacryocystorhinostomy (CDCR) with frosted Jones tubes (FJT) for epiphora with proximal outflow obstruction. Methods: A retrospective...
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Early oral immunotherapy in peanut-allergic preschool children is safe and highly effective
Oral immunotherapy (OIT) is an effective experimental food allergy treatment that is limited by treatment withdrawal and the frequent reversibility of desensitization if interrupted. Newly diagnosed preschool children may have clinical and immunological characteristics more amenable to treatment. from...
health683
Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer
Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer: Abstract Background The purpose of this study was to investigate the effects of combining the phosphotidylinositol-3-kinase (PI3K) inhibitor...
health683
DNA-PkCS expression in oropharyngeal squamous cell carcinoma: Correlations with human papillomavirus status and recurrence after transoral robotic surgery
DNA-PkCS expression in oropharyngeal squamous cell carcinoma: Correlations with human papillomavirus status and recurrence after transoral robotic surgery: Abstract Background Human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (SCC) has improved clinical outcomes compared to...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
The Potential Use of Piglets as Human Pediatric Surrogate for Preclinical Pharmacokinetic and Pharmacodynamic Drug Testing
The Potential Use of Piglets as Human Pediatric Surrogate for Preclinical Pharmacokinetic and Pharmacodynamic Drug Testing: Pediatric drug research is still substandard, not reaching the same quality level as adult drug research. Despite the efforts made by the Food and Drug Administration and European...
health683
Predisposing factors for poor prognosis of angiosarcoma of the scalp and face: Systematic review and meta-analysis
Predisposing factors for poor prognosis of angiosarcoma of the scalp and face: Systematic review and meta-analysis: ABSTRACT Background Angiosarcoma of the scalp and face is an aggressive tumor with a high rate of local recurrence. Although many previous studies have demonstrated risk factors for...
health683
Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer
Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer: Abstract Background This study is an evaluation of survival in patients with upper aerodigestive tract (UADT) cancer who did not receive guideline-directed therapy. Methods The National Cancer Institute’s Surveillance,...
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The allergen Mus m 1.0102: Dissecting the relationship between molecular conformation and allergenic potency
Publication date: Available online 9 August 2016Source:Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics Author(s): Elena Ferrari, Emanuela Casali, Samuele E. Burastero, Alberto Spisni, Thelma A. Pertinhez BackgroundThe species Mus musculus experiences an obligate proteinuria: predominant...
health683
Radiotherapy in early-stage tongue squamous cell carcinoma with minor adverse features
Radiotherapy in early-stage tongue squamous cell carcinoma with minor adverse features: Abstract Background Treatment for early-stage tongue squamous cell carcinoma (SCC) is usually surgery alone. There is ambiguity regarding the impact of minor adverse features (MAFs) on outcome and the role of...
health683
Impact of chemotherapy on the outcome of osteosarcoma of the head and neck in adults
Impact of chemotherapy on the outcome of osteosarcoma of the head and neck in adults: Abstract Background There is an ongoing debate about the value of (neo-)adjuvant chemotherapy in high- and intermediate-grade osteosarcoma of the head and neck. Methods All records of patients older than 16 years...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
A Case Indistinguishable Between Indeterminate Cell Histiocytosis and Cutaneous Rosai-Dorfman Disease
A Case Indistinguishable Between Indeterminate Cell Histiocytosis and Cutaneous Rosai-Dorfman Disease Cutaneous Rosai–Dorfman disease is a distinct clinical entity T Brenn, E Calonje, SR Granter… – The American journal …, 2002 – journals.lww.com … Further special stains revealed focal weak positivity...
health683
Improvement in symptoms of obstructive sleep apnoea in children following tonsillectomy versus tonsillotomy: a systematic review and meta-analysis
Improvement in symptoms of obstructive sleep apnoea in children following tonsillectomy versus tonsillotomy: a systematic review and meta-analysis: Abstract Background Tonsillotomy (or intracapsular tonsillectomy) is a modern technique which is seen by some as potentially superior to traditional...
health683
Comparison of the Motor Performance and Vestibular Function in Infants with a Congenital Cytomegalovirus Infection or a Connexin 26 Mutation: A Preliminary Study.
Comparison of the Motor Performance and Vestibular Function in Infants with a Congenital Cytomegalovirus Infection or a Connexin 26 Mutation: A Preliminary Study.: Objectives: Hearing-impaired children are at risk for vestibular damage and delayed motor development. Two major causes of congenital...
health683
Infant Cortical Auditory Evoked Potentials to Lateralized Noise Shifts Produced by Changes in Interaural Time Difference.
Infant Cortical Auditory Evoked Potentials to Lateralized Noise Shifts Produced by Changes in Interaural Time Difference.: Objectives: Newborns reliably orient to sound location soon after birth; by age 1 month this orienting disappears until after age 4 months. It has been suggested that orienting...
health683
The Effectiveness and Long-Term Outcome of Conjunctivodacryocystorhinostomy With Frosted Jones Tubes.
The Effectiveness and Long-Term Outcome of Conjunctivodacryocystorhinostomy With Frosted Jones Tubes.: Purpose: To describe success rates and long-term outcomes of conjunctivodacryocystorhinostomy (CDCR) with frosted Jones tubes (FJT) for epiphora with proximal outflow obstruction. Methods: A retrospective...
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Quantitative proteome analysis reveals the correlation between endocytosis-associated proteins and hepatocellular carcinoma dedifferentiation
Publication date: Available online 9 August 2016Source:Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics Author(s): Wael Naboulsi, Thilo Bracht, Dominik A. Megger, Henning Reis, Maike Ahrens, Michael Turewicz, Martin Eisenacher, Stephanie Tautges, Ali E. Canbay, Helmut E. Meyer, Frank Weber,...
health683
A Case Indistinguishable Between Indeterminate Cell Histiocytosis and Cutaneous Rosai-Dorfman Disease
A Case Indistinguishable Between Indeterminate Cell Histiocytosis and Cutaneous Rosai-Dorfman Disease Cutaneous Rosai–Dorfman disease is a distinct clinical entity T Brenn, E Calonje, SR Granter… – The American journal …, 2002 – journals.lww.com… Further special stains revealed focal weak positivity...
health683
The Potential Use of Piglets as Human Pediatric Surrogate for Preclinical Pharmacokinetic and Pharmacodynamic Drug Testing
The Potential Use of Piglets as Human Pediatric Surrogate for Preclinical Pharmacokinetic and Pharmacodynamic Drug Testing: Pediatric drug research is still substandard, not reaching the same quality level as adult drug research. Despite the efforts made by the Food and Drug Administration and European...
health683
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar: Objective Persistent dysphonia from vocal fold scar remains a clinical challenge, with current therapies providing inconsistent outcomes. We evaluated voice outcomes after a single office-based steroid injection. Study...
health683
Screening patients for communication difficulty: The diagnostic accuracy of the IFCI staff questionnaire
Screening patients for communication difficulty: The diagnostic accuracy of the IFCI staff questionnaire Abstract Purpose: Many patients have difficulty communicating about their healthcare. At present there is no tool to identify these patients. This research investigated whether the Inpatient Functional...
health683
The six-food elimination diet (SFED), where dairy, wheat, eggs, soy, nuts, and seafood are avoided, is an effective treatment for eosinophilic esophagitis (EoE).
The Six-Food Elimination Diet for Eosinophilic Esophagitis Increases Grocery Shopping Cost and Complexity: Abstract The six-food elimination diet (SFED), where dairy, wheat, eggs, soy, nuts, and seafood are avoided, is an effective treatment for eosinophilic esophagitis (EoE). Patient-related costs...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Screening patients for communication difficulty: The diagnostic accuracy of the IFCI staff questionnaire
Screening patients for communication difficulty: The diagnostic accuracy of the IFCI staff questionnaire Abstract Purpose: Many patients have difficulty communicating about their healthcare. At present there is no tool to identify these patients. This research investigated whether the Inpatient Functional...
health683
Two Sensory Stimulation Strategies After Two Weeks Treatment on Older Patients with Oropharyngeal Dysphagia
A Comparative Study Between Abstract Oropharyngeal dysphagia (OD) is a prevalent geriatric syndrome. Treatment is based on compensatory strategies to avoid complications. New treatments based on sensory stimulation to promote the recovery of the swallowing function have proved effective in acute...
health683
Volume measurements on three-dimensional photogrammetry after extended strip versus total cranial remodeling for sagittal synostosis: A comparative cohort study
Volume measurements on three-dimensional photogrammetry after extended strip versus total cranial remodeling for sagittal synostosis: A comparative cohort study: Surgery for sagittal synostosis aims at correction of skull shape and restoration of growth potential. Small cranial volume is associated with...
health683
Five-Year Speech and Language Outcomes in Children with Cleft Lip-Palate
Five-Year Speech and Language Outcomes in Children with Cleft Lip-Palate: Objective: To investigate 5-year speech and language outcomes in children with cleft lip/palate (CLP).Materials and methods: Thirty-eight children aged 4-7 years and 8 months were recruited for this study. Speech abilities including...
health683
The histamine skin prick test
The histamine skin prick test: Histamine-induced wheals and flares induced by skin prick tests (SPTs) may be used beyond the typical clinical setting as pharmacodynamic markers in clinical trials. The wheal and flare areas may be measured at multiple time points and an area under the curve calculated...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar: Objective Persistent dysphonia from vocal fold scar remains a clinical challenge, with current therapies providing inconsistent outcomes. We evaluated voice outcomes after a single office-based steroid injection. Study...
health683
Evaluation of surgical outcome and influencing risk factors in patients with medication-related osteonecrosis of the jaws
Evaluation of surgical outcome and influencing risk factors in patients with medication-related osteonecrosis of the jaws: Surgical treatment of the medication-related osteonecrosis of the jaw (MRONJ) is still challenging. We examined the outcome of the resection of osteonecrotic lesions and the influence...
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Comparative functional characterization of eugenol synthase from four different Ocimum species: Implications on eugenol accumulation
Publication date: Available online 9 August 2016Source:Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics Author(s): Atul Anand, Ramesha H. Jayaramaiah, Supriya D. Beedkar, Priyanka A. Singh, Rakesh S. Joshi, Fayaj A. Mulani, Bhushan B. Dholakia, Sachin A. Punekar, Wasudeo N. Gade, Hirekodathakallu...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
The six-food elimination diet (SFED), where dairy, wheat, eggs, soy, nuts, and seafood are avoided, is an effective treatment for eosinophilic esophagitis (EoE).
The Six-Food Elimination Diet for Eosinophilic Esophagitis Increases Grocery Shopping Cost and Complexity: Abstract The six-food elimination diet (SFED), where dairy, wheat, eggs, soy, nuts, and seafood are avoided, is an effective treatment for eosinophilic esophagitis (EoE). Patient-related costs...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Two Sensory Stimulation Strategies After Two Weeks Treatment on Older Patients with Oropharyngeal Dysphagia
A Comparative Study Between  Abstract Oropharyngeal dysphagia (OD) is a prevalent geriatric syndrome. Treatment is based on compensatory strategies to avoid complications. New treatments based on sensory stimulation to promote the recovery of the swallowing function have proved effective in acute studies...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
The histamine skin prick test
The histamine skin prick test: Histamine-induced wheals and flares induced by skin prick tests (SPTs) may be used beyond the typical clinical setting as pharmacodynamic markers in clinical trials. The wheal and flare areas may be measured at multiple time points and an area under the curve calculated...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Volume measurements on three-dimensional photogrammetry after extended strip versus total cranial remodeling for sagittal synostosis: A comparative cohort study
Volume measurements on three-dimensional photogrammetry after extended strip versus total cranial remodeling for sagittal synostosis: A comparative cohort study: Surgery for sagittal synostosis aims at correction of skull shape and restoration of growth potential. Small cranial volume is associated with...


health683
Comparison of the Motor Performance and Vestibular Function in Infants with a Congenital Cytomegalovirus Infection or a Connexin 26 Mutation: A Preliminary Study.
Comparison of the Motor Performance and Vestibular Function in Infants with a Congenital Cytomegalovirus Infection or a Connexin 26 Mutation: A Preliminary Study.: Objectives: Hearing-impaired children are at risk for vestibular damage and delayed motor development. Two major causes of congenital...
health683
Infant Cortical Auditory Evoked Potentials to Lateralized Noise Shifts Produced by Changes in Interaural Time Difference.
Infant Cortical Auditory Evoked Potentials to Lateralized Noise Shifts Produced by Changes in Interaural Time Difference.: Objectives: Newborns reliably orient to sound location soon after birth; by age 1 month this orienting disappears until after age 4 months. It has been suggested that orienting...
health683
The Effectiveness and Long-Term Outcome of Conjunctivodacryocystorhinostomy With Frosted Jones Tubes.
The Effectiveness and Long-Term Outcome of Conjunctivodacryocystorhinostomy With Frosted Jones Tubes.: Purpose: To describe success rates and long-term outcomes of conjunctivodacryocystorhinostomy (CDCR) with frosted Jones tubes (FJT) for epiphora with proximal outflow obstruction. Methods: A retrospective...
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Quantitative proteome analysis reveals the correlation between endocytosis-associated proteins and hepatocellular carcinoma dedifferentiation
Publication date: Available online 9 August 2016Source:Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics Author(s): Wael Naboulsi, Thilo Bracht, Dominik A. Megger, Henning Reis, Maike Ahrens, Michael Turewicz, Martin Eisenacher, Stephanie Tautges, Ali E. Canbay, Helmut E. Meyer, Frank Weber,...
health683
A Case Indistinguishable Between Indeterminate Cell Histiocytosis and Cutaneous Rosai-Dorfman Disease
A Case Indistinguishable Between Indeterminate Cell Histiocytosis and Cutaneous Rosai-Dorfman Disease Cutaneous Rosai–Dorfman disease is a distinct clinical entity T Brenn, E Calonje, SR Granter… – The American journal …, 2002 – journals.lww.com… Further special stains revealed focal weak positivity...
health683
The Potential Use of Piglets as Human Pediatric Surrogate for Preclinical Pharmacokinetic and Pharmacodynamic Drug Testing
The Potential Use of Piglets as Human Pediatric Surrogate for Preclinical Pharmacokinetic and Pharmacodynamic Drug Testing: Pediatric drug research is still substandard, not reaching the same quality level as adult drug research. Despite the efforts made by the Food and Drug Administration and European...
health683
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar: Objective Persistent dysphonia from vocal fold scar remains a clinical challenge, with current therapies providing inconsistent outcomes. We evaluated voice outcomes after a single office-based steroid injection. Study...
health683
Screening patients for communication difficulty: The diagnostic accuracy of the IFCI staff questionnaire
Screening patients for communication difficulty: The diagnostic accuracy of the IFCI staff questionnaire Abstract Purpose: Many patients have difficulty communicating about their healthcare. At present there is no tool to identify these patients. This research investigated whether the Inpatient Functional...
health683
The six-food elimination diet (SFED), where dairy, wheat, eggs, soy, nuts, and seafood are avoided, is an effective treatment for eosinophilic esophagitis (EoE).
The Six-Food Elimination Diet for Eosinophilic Esophagitis Increases Grocery Shopping Cost and Complexity: Abstract The six-food elimination diet (SFED), where dairy, wheat, eggs, soy, nuts, and seafood are avoided, is an effective treatment for eosinophilic esophagitis (EoE). Patient-related costs...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Screening patients for communication difficulty: The diagnostic accuracy of the IFCI staff questionnaire
Screening patients for communication difficulty: The diagnostic accuracy of the IFCI staff questionnaire Abstract Purpose: Many patients have difficulty communicating about their healthcare. At present there is no tool to identify these patients. This research investigated whether the Inpatient Functional...
health683
Two Sensory Stimulation Strategies After Two Weeks Treatment on Older Patients with Oropharyngeal Dysphagia
A Comparative Study Between Abstract Oropharyngeal dysphagia (OD) is a prevalent geriatric syndrome. Treatment is based on compensatory strategies to avoid complications. New treatments based on sensory stimulation to promote the recovery of the swallowing function have proved effective in acute...
health683
Volume measurements on three-dimensional photogrammetry after extended strip versus total cranial remodeling for sagittal synostosis: A comparative cohort study
Volume measurements on three-dimensional photogrammetry after extended strip versus total cranial remodeling for sagittal synostosis: A comparative cohort study: Surgery for sagittal synostosis aims at correction of skull shape and restoration of growth potential. Small cranial volume is associated with...
health683
Five-Year Speech and Language Outcomes in Children with Cleft Lip-Palate
Five-Year Speech and Language Outcomes in Children with Cleft Lip-Palate: Objective: To investigate 5-year speech and language outcomes in children with cleft lip/palate (CLP).Materials and methods: Thirty-eight children aged 4-7 years and 8 months were recruited for this study. Speech abilities including...
health683
The histamine skin prick test
The histamine skin prick test: Histamine-induced wheals and flares induced by skin prick tests (SPTs) may be used beyond the typical clinical setting as pharmacodynamic markers in clinical trials. The wheal and flare areas may be measured at multiple time points and an area under the curve calculated...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar: Objective Persistent dysphonia from vocal fold scar remains a clinical challenge, with current therapies providing inconsistent outcomes. We evaluated voice outcomes after a single office-based steroid injection. Study...
health683
Evaluation of surgical outcome and influencing risk factors in patients with medication-related osteonecrosis of the jaws
Evaluation of surgical outcome and influencing risk factors in patients with medication-related osteonecrosis of the jaws: Surgical treatment of the medication-related osteonecrosis of the jaw (MRONJ) is still challenging. We examined the outcome of the resection of osteonecrotic lesions and the influence...
Human Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Comparative functional characterization of eugenol synthase from four different Ocimum species: Implications on eugenol accumulation
Publication date: Available online 9 August 2016Source:Biochimica et Biophysica Acta (BBA) – Proteins and Proteomics Author(s): Atul Anand, Ramesha H. Jayaramaiah, Supriya D. Beedkar, Priyanka A. Singh, Rakesh S. Joshi, Fayaj A. Mulani, Bhushan B. Dholakia, Sachin A. Punekar, Wasudeo N. Gade, Hirekodathakallu...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
The six-food elimination diet (SFED), where dairy, wheat, eggs, soy, nuts, and seafood are avoided, is an effective treatment for eosinophilic esophagitis (EoE).
The Six-Food Elimination Diet for Eosinophilic Esophagitis Increases Grocery Shopping Cost and Complexity: Abstract The six-food elimination diet (SFED), where dairy, wheat, eggs, soy, nuts, and seafood are avoided, is an effective treatment for eosinophilic esophagitis (EoE). Patient-related costs...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Two Sensory Stimulation Strategies After Two Weeks Treatment on Older Patients with Oropharyngeal Dysphagia
A Comparative Study Between  Abstract Oropharyngeal dysphagia (OD) is a prevalent geriatric syndrome. Treatment is based on compensatory strategies to avoid complications. New treatments based on sensory stimulation to promote the recovery of the swallowing function have proved effective in acute studies...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
The histamine skin prick test
The histamine skin prick test: Histamine-induced wheals and flares induced by skin prick tests (SPTs) may be used beyond the typical clinical setting as pharmacodynamic markers in clinical trials. The wheal and flare areas may be measured at multiple time points and an area under the curve calculated...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Volume measurements on three-dimensional photogrammetry after extended strip versus total cranial remodeling for sagittal synostosis: A comparative cohort study
Volume measurements on three-dimensional photogrammetry after extended strip versus total cranial remodeling for sagittal synostosis: A comparative cohort study: Surgery for sagittal synostosis aims at correction of skull shape and restoration of growth potential. Small cranial volume is associated with...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Evaluation of surgical outcome and influencing risk factors in patients with medication-related osteonecrosis of the jaws
Evaluation of surgical outcome and influencing risk factors in patients with medication-related osteonecrosis of the jaws: Surgical treatment of the medication-related osteonecrosis of the jaw (MRONJ) is still challenging. We examined the outcome of the resection of osteonecrotic lesions and the influence...
OtoRhinoLaryngology by Sfakianakis G.Alexandros
Five-Year Speech and Language Outcomes in Children with Cleft Lip-Palate
Five-Year Speech and Language Outcomes in Children with Cleft Lip-Palate: Objective: To investigate 5-year speech and language outcomes in children with cleft lip/palate (CLP).Materials and methods: Thirty-eight children aged 4-7 years and 8 months were recruited for this study. Speech abilities including...
ORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Early oral immunotherapy in peanut-allergic preschool children is safe and highly effective
Oral immunotherapy (OIT) is an effective experimental food allergy treatment that is limited by treatment withdrawal and the frequent reversibility of desensitization if interrupted. Newly diagnosed preschool children may have clinical and immunological characteristics more amenable to treatment. from...
medicinealexandrossfakianakis
Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer
Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer: Abstract Background The purpose of this study was to investigate the effects of combining the phosphotidylinositol-3-kinase (PI3K)...
medicinealexandrossfakianakis
DNA-PkCS expression in oropharyngeal squamous cell carcinoma: Correlations with human papillomavirus status and recurrence after transoral robotic surgery
DNA-PkCS expression in oropharyngeal squamous cell carcinoma: Correlations with human papillomavirus status and recurrence after transoral robotic surgery: Abstract Background Human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (SCC) has improved clinical outcomes compared...
medicinealexandrossfakianakis
Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer
Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer: Abstract Background This study is an evaluation of survival in patients with upper aerodigestive tract (UADT) cancer who did not receive guideline-directed therapy. Methods The National Cancer Institute’s...
medicinealexandrossfakianakis
Predisposing factors for poor prognosis of angiosarcoma of the scalp and face: Systematic review and meta-analysis
Predisposing factors for poor prognosis of angiosarcoma of the scalp and face: Systematic review and meta-analysis: ABSTRACT Background Angiosarcoma of the scalp and face is an aggressive tumor with a high rate of local recurrence. Although many previous studies have demonstrated risk factors for...
medicinealexandrossfakianakis
Radiotherapy in early-stage tongue squamous cell carcinoma with minor adverse features
Radiotherapy in early-stage tongue squamous cell carcinoma with minor adverse features: Abstract Background Treatment for early-stage tongue squamous cell carcinoma (SCC) is usually surgery alone. There is ambiguity regarding the impact of minor adverse features (MAFs) on outcome and the role of...
medicinealexandrossfakianakis
Impact of chemotherapy on the outcome of osteosarcoma of the head and neck in adults
Impact of chemotherapy on the outcome of osteosarcoma of the head and neck in adults: Abstract Background There is an ongoing debate about the value of (neo-)adjuvant chemotherapy in high- and intermediate-grade osteosarcoma of the head and neck. Methods All records of patients older than...
medicinealexandrossfakianakis
Improvement in symptoms of obstructive sleep apnoea in children following tonsillectomy versus tonsillotomy: a systematic review and meta-analysis
Improvement in symptoms of obstructive sleep apnoea in children following tonsillectomy versus tonsillotomy: a systematic review and meta-analysis: Abstract Background Tonsillotomy (or intracapsular tonsillectomy) is a modern technique which is seen by some as potentially superior to traditional...
medicinealexandrossfakianakis
Comparison of the Motor Performance and Vestibular Function in Infants with a Congenital Cytomegalovirus Infection or a Connexin 26 Mutation: A Preliminary Study.
Comparison of the Motor Performance and Vestibular Function in Infants with a Congenital Cytomegalovirus Infection or a Connexin 26 Mutation: A Preliminary Study.: Objectives: Hearing-impaired children are at risk for vestibular damage and delayed motor development. Two major causes of congenital...
medicinealexandrossfakianakis
Infant Cortical Auditory Evoked Potentials to Lateralized Noise Shifts Produced by Changes in Interaural Time Difference.
Infant Cortical Auditory Evoked Potentials to Lateralized Noise Shifts Produced by Changes in Interaural Time Difference.: Objectives: Newborns reliably orient to sound location soon after birth; by age 1 month this orienting disappears until after age 4 months. It has been suggested that orienting...
medicinealexandrossfakianakis
A Case Indistinguishable Between Indeterminate Cell Histiocytosis and Cutaneous Rosai-Dorfman Disease
A Case Indistinguishable Between Indeterminate Cell Histiocytosis and Cutaneous Rosai-Dorfman Disease Cutaneous Rosai–Dorfman disease is a distinct clinical entity T Brenn, E Calonje, SR Granter… – The American journal …, 2002 – journals.lww.com … Further special stains revealed focal weak positivity...
medicinealexandrossfakianakis
The Potential Use of Piglets as Human Pediatric Surrogate for Preclinical Pharmacokinetic and Pharmacodynamic Drug Testing
The Potential Use of Piglets as Human Pediatric Surrogate for Preclinical Pharmacokinetic and Pharmacodynamic Drug Testing: Pediatric drug research is still substandard, not reaching the same quality level as adult drug research. Despite the efforts made by the Food and Drug Administration and European...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Usage of personal music players in adolescents and its association with noise-induced hearing loss: A cross-sectional analysis of Ohrkan cohort study data
Usage of personal music players in adolescents and its association with noise-induced hearing loss: A cross-sectional analysis of Ohrkan cohort study dataAbstractObjective: To describe personal music player (PMP) usage among adolescents, sociodemographic determinants and association with audiometric...
medicinealexandrossfakianakis
Screening patients for communication difficulty: The diagnostic accuracy of the IFCI staff questionnaire
Screening patients for communication difficulty: The diagnostic accuracy of the IFCI staff questionnaire Abstract Purpose: Many patients have difficulty communicating about their healthcare. At present there is no tool to identify these patients. This research investigated whether the Inpatient Functional...
medicinealexandrossfakianakis
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar
Voice Outcomes following a Single Office-Based Steroid Injection for Vocal Fold Scar: Objective Persistent dysphonia from vocal fold scar remains a clinical challenge, with current therapies providing inconsistent outcomes. We evaluated voice outcomes after a single office-based steroid injection. Study...
medicinealexandrossfakianakis
The six-food elimination diet (SFED), where dairy, wheat, eggs, soy, nuts, and seafood are avoided, is an effective treatment for eosinophilic esophagitis (EoE).
The Six-Food Elimination Diet for Eosinophilic Esophagitis Increases Grocery Shopping Cost and Complexity: Abstract The six-food elimination diet (SFED), where dairy, wheat, eggs, soy, nuts, and seafood are avoided, is an effective treatment for eosinophilic esophagitis (EoE). Patient-related costs...
medicinealexandrossfakianakis
Two Sensory Stimulation Strategies After Two Weeks Treatment on Older Patients with Oropharyngeal Dysphagia
A Comparative Study Between  Abstract Oropharyngeal dysphagia (OD) is a prevalent geriatric syndrome. Treatment is based on compensatory strategies to avoid complications. New treatments based on sensory stimulation to promote the recovery of the swallowing function have proved effective in acute studies...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Estimating audiometric thresholds using simultaneous acquisition of ASSR and ABR from QASSR in patients with sensorineural hearing loss
Estimating audiometric thresholds using simultaneous acquisition of ASSR and ABR from QASSR in patients with sensorineural hearing lossAbstractObjectives: To evaluate the accuracy with which the innovative QASSR method predicts behavioral thresholds in adult patients with sensorineural hearing loss....
medicinealexandrossfakianakis
The histamine skin prick test
The histamine skin prick test: Histamine-induced wheals and flares induced by skin prick tests (SPTs) may be used beyond the typical clinical setting as pharmacodynamic markers in clinical trials. The wheal and flare areas may be measured at multiple time points and an area under the curve calculated...
medicinealexandrossfakianakis
Volume measurements on three-dimensional photogrammetry after extended strip versus total cranial remodeling for sagittal synostosis: A comparative cohort study
Volume measurements on three-dimensional photogrammetry after extended strip versus total cranial remodeling for sagittal synostosis: A comparative cohort study: Surgery for sagittal synostosis aims at correction of skull shape and restoration of growth potential. Small cranial volume is associated with...
medicinealexandrossfakianakis
Evaluation of surgical outcome and influencing risk factors in patients with medication-related osteonecrosis of the jaws
Evaluation of surgical outcome and influencing risk factors in patients with medication-related osteonecrosis of the jaws: Surgical treatment of the medication-related osteonecrosis of the jaw (MRONJ) is still challenging. We examined the outcome of the resection of osteonecrotic lesions and the influence...
medicinealexandrossfakianakis
Five-Year Speech and Language Outcomes in Children with Cleft Lip-Palate
Five-Year Speech and Language Outcomes in Children with Cleft Lip-Palate: Objective: To investigate 5-year speech and language outcomes in children with cleft lip/palate (CLP).Materials and methods: Thirty-eight children aged 4-7 years and 8 months were recruited for this study. Speech abilities including...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer
Combination of phosphotidylinositol-3-kinase targeting with cetuximab and irradiation: A preclinical study on an orthotopic xenograft model of head and neck cancer: AbstractBackgroundThe purpose of this study was to investigate the effects of combining the phosphotidylinositol-3-kinase (PI3K) inhibitor...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
DNA-PkCS expression in oropharyngeal squamous cell carcinoma: Correlations with human papillomavirus status and recurrence after transoral robotic surgery
DNA-PkCS expression in oropharyngeal squamous cell carcinoma: Correlations with human papillomavirus status and recurrence after transoral robotic surgery: AbstractBackgroundHuman papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (SCC) has improved clinical outcomes compared to HPV-negative...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer
Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer: AbstractBackgroundThis study is an evaluation of survival in patients with upper aerodigestive tract (UADT) cancer who did not receive guideline-directed therapy.MethodsThe National Cancer Institute's Surveillance,...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Predisposing factors for poor prognosis of angiosarcoma of the scalp and face: Systematic review and meta-analysis
Predisposing factors for poor prognosis of angiosarcoma of the scalp and face: Systematic review and meta-analysis: ABSTRACTBackgroundAngiosarcoma of the scalp and face is an aggressive tumor with a high rate of local recurrence. Although many previous studies have demonstrated risk factors for poor...
OtoRhinoLaryngology - Alexandros G. Sfakianakis
Radiotherapy in early-stage tongue squamous cell carcinoma with minor adverse features
Radiotherapy in early-stage tongue squamous cell carcinoma with minor adverse features: AbstractBackgroundTreatment for early-stage tongue squamous cell carcinoma (SCC) is usually surgery alone. There is ambiguity regarding the impact of minor adverse features (MAFs) on outcome and the role of postoperative...


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