Host and clinical aspects in patients with benign migratory glossitis

Publication date: January 2017
Source:Archives of Oral Biology, Volume 73
Author(s): Rafaela Scariot, Thiago Beltrami Dias Batista, Marcia Olandoski, Cleber Machado Souza, Paulo Henrique Couto Souza, Antonio Adilson Soares Lima, Paula Cristina Trevilatto
ObjectiveInvestigate the association of clinical, cytological and genetic characteristics with benign migratory glossitis (BMG).Study designSample consisted of 175 patients, 44 with BMG and 131 control patients. Clinical examination and DMFT index were assessed. Cytological evaluation determined cell morphology and morphometry. Genetic evaluation was performed by analysing IL6 polymorphisms by real-time PCR. Univariate and multivariate analyses were performed (p<0.05).ResultsThere was a higher level of anxiety, DMFT score and a prevalence of fissured tongue in BMG group. A high mean nuclear/cytoplasmic area ratio was observed in patients with BMG. There was predominance of Papanicolaou class II I BMG group. IL6 allele G rs2069843 polymorphism was associated with BMG in the dominant model. In multivariate analysis, DMFT and anxiety scale remained associated with BMG.



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