Prenatal phthalate exposure associates with low regulatory T cell numbers and atopic dermatitis in early childhood – results from the LINA mother-child study

Publication date: Available online 5 November 2016
Source:Journal of Allergy and Clinical Immunology
Author(s): Gunda Herberth, Arkadiusz Pierzchalski, Ralph Feltens, Mario Bauer, Stefan Röder, Sven Olek, Denise Hinz, Michael Borte, Martin von Bergen, Irina Lehmann

Teaser

Exposure to high concentrations of the phthalate metabolite mono-isobutyl phthalate (MiBP) in the prenatal period is a risk factor for atopic dermatitis in early childhood, presumably by inhibiting the development of regulatory T cells.


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