Anaphylaxis after Zoster Vaccine: Implicating Alpha-Gal Allergy as a Possible Mechanism

Publication date: Available online 14 December 2016
Source:Journal of Allergy and Clinical Immunology
Author(s): Cosby A. Stone, Jonathan A. Hemler, Scott P. Commins, Alexander P. Schuyler, Elizabeth J. Phillips, R. Stokes Peebles, John M. Fahrenholz

Teaser

A patient with alpha-gal allergy presented with anaphylaxis after receiving zoster vaccine. Subsequent testing of selected vaccines revealed the presence of alpha-gal allergen in MMR and zoster vaccines, which have in common a higher content of gelatin and content of bovine calf serum.


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