EGFRI-induced papulopustular rosacea-like rash successfully treated with topical ivermectin

Abstract

A 63-year-old Caucasian man presented with a three weeks history of multiple erythematous, rosacea-like, facial and thoracic papules and pustules. No mucosal lesions were present. The patient received a combined therapy for metastatic colon carcinoma with cetuximab 500 mg/m²/week plus capecitabine 500 mg/week; just after the onset he developed the papulopustular rash first on his face with subsequent expansion to the thorax (figure 1, A, B).

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